Takeda Yukimasa 武田行正

… Alternative Names

Yukimasa Takeda 武田行正

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Researcher Number	40735552
Other IDs
Affiliation (Current)	2025: 近畿大学, 産業理工学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related / Developmental biology Except Principal Investigator Basic Section 90110:Biomedical engineering-related / General medical chemistry
Keywords	Principal Investigator 褐色脂肪細胞 / 再生医療 / 生活習慣病 / 肥満 / 低分子化合物 / ダイレクトリプログラミング / 一細胞遺伝子発現解析 / 糖尿病 / 個別化医療 / 細胞移植治療 … More / インスリン産生細胞 / 神経幹細胞 / シグナル伝達経路 / 人工多能性幹細胞 / 分化全能性 / 母性効果因子 / リプログラミング … More Except Principal Investigator 低分子化合物 / ダイレクトリプログラミング / 筋萎縮性側索硬化症 / パーキンソン病 / ドーパミンニューロン / ドーパミン作動ニューロン / オリゴデンドロサイト / 運動ニューロン / ドーパミン作動性ニューロン / 神経変性疾患 / 糖・脂質代謝 / 糖尿病 / ダイレクトリプログラミン / 再生医学 / 再生医療 / 細胞移植治療 / 褐色脂肪細胞 Less

Development of a novel technology for the proliferation of human brown adipocytes by inducing preadipocytes.Principal Investigator
- Principal Investigator
  
  武田行正
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto Prefectural University of Medicine
Establishment of a novel model for human beige adipocytes converted from smooth muscle-like cellsPrincipal Investigator
- Principal Investigator
  
  Takeda Yukimasa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of non-transgenetic direct reprogramming method for human neuronal subtypes
- Principal Investigator
  
  Dai Ping
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto Prefectural University of Medicine
Direct reprogramming to desired cell types applicable for regenerative medicine in a transgene-free mannerPrincipal Investigator
- Principal Investigator
  
  Takeda Yukimasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto Prefectural University of Medicine
Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds
- Principal Investigator
  
  Dai Ping
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Reprogramming into induced totipotent stem cells by maternal factorsPrincipal Investigator
- Principal Investigator
  
  Yukimasa Takeda
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Precision Medicine　研究者の最新動向「ヒト褐色脂肪細胞を用いた褐色化機構の解明」2023
- Author(s)
  武田行正、戴平
- Total Pages
  86
- Publisher
  株式会社北隆館
- Data Source
  KAKENHI-PROJECT-21K12669
[Book] 「Precision Medicine」2023年1月号6巻　研究者の最新動向「ヒト褐色脂肪細胞を用いた褐色化機構の解明」2023
- Author(s)
  武田行正、戴平
- Total Pages
  86
- Publisher
  株式会社北隆館
- Data Source
  KAKENHI-PROJECT-21K12669
[Book] 「Medical Science Digest」2023年10月号49巻　最先端医療の今「ヒト褐色脂肪細胞モデルを用いたUCP1の発現制御機構の解明」2023
- Author(s)
  武田行正、戴平
- Total Pages
  56
- Publisher
  株式会社ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K12669
[Book] Bio Clinica　BIOLOGY TOPICS 「ヒト皮膚線維芽細胞から誘導される褐色脂肪細胞とその応用」2022
- Author(s)
  武田行正、戴平
- Total Pages
  92
- Publisher
  株式会社北隆館
- Data Source
  KAKENHI-PROJECT-21K12669
[Book] Precision Medicine 研究者の最新動向「ヒト褐色脂肪細胞のケミカルダイレクトリプログラミング」2021
- Author(s)
  武田行正、戴平
- Total Pages
  3
- Publisher
  株式会社北隆館
- Data Source
  KAKENHI-PROJECT-21K12669
[Book] Medical Science Digest2021
- Author(s)
  武田行正、戴平
- Total Pages
  2
- Publisher
  株式会社ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-18K12038
[Book] Medical Science Digest2021
- Author(s)
  武田行正、戴平
- Total Pages
  2
- Publisher
  株式会社ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-19K12788
[Book] Medical Science Digest 最先端医療の今「低分子化合物によるヒト褐色脂肪細胞のダイレクトリプログラミング」2021
- Author(s)
  武田行正、戴平
- Total Pages
  2
- Publisher
  株式会社ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K12669
[Book] ダイレクトリプログラミング-再生医療の新展開　第２編第６章2020
- Author(s)
  武田行正、戴平
- Total Pages
  11
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-19K12788
[Book] ダイレクトリプログラミング-再生医療の新展開　第２編第６章2020
- Author(s)
  武田行正、戴平
- Total Pages
  11
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-18K12038
[Journal Article] Mitochondrial energy metabolism in the regulation of brown fats and human metabolic diseases.2023
- Author(s)
  Takeda Y., Harada Y., Yoshikawa T., and Dai P
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 24 Issue: 2 Pages: 1352-1352
- DOI
  10.3390/ijms24021352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12669, KAKENHI-PROJECT-22K12769
[Journal Article] Capsaicin directly promotes adipocyte browning in the chemical compound-induced brown adipocytes converted from human dermal fibroblasts.2022
- Author(s)
  Takeda Yukimasa, Dai Ping
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 6612-6612
- DOI
  10.1038/s41598-022-10644-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12669, KAKENHI-PROJECT-22K12769
[Journal Article] Chronic Fatty Acid Depletion Induces Uncoupling Protein 1 (UCP1) Expression to Coordinate Mitochondrial Inducible Proton Leak in a Human-Brown-Adipocyte Model.2022
- Author(s)
  Takeda Y. and Dai P
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 13 Pages: 2038-2038
- DOI
  10.3390/cells11132038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12669, KAKENHI-PROJECT-22K12769
[Journal Article] Transcriptome analysis reveals brown adipogenic reprogramming in chemical compound-induced brown adipocytes converted from human dermal fibroblasts2021
- Author(s)
  Takeda Yukimasa, Yoshikawa Toshikazu, Dai Ping
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5061-5061
- DOI
  10.1038/s41598-021-84611-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12788, KAKENHI-PROJECT-18K12038
[Journal Article] A developed serum-free medium and optimized chemical cocktail for direct conversion of human dermal fibroblasts into brown adipocytes2020
- Author(s)
  Takeda Y. and Dai P.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 3775-3775
- DOI
  10.1038/s41598-020-60769-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12038, KAKENHI-PROJECT-19K12788
[Journal Article] Analysis of the Transcriptional Activity of Retinoic Acid-Related Orphan Receptors (RORs) and Inhibition by Inverse Agonists.2019
- Author(s)
  Takeda Y., Kang H.S., and Jetten A.M.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1966 Pages: 193-202
- DOI
  10.1007/978-1-4939-9195-2_15
- ISBN
  9781493991945, 9781493991952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K12038
[Journal Article] Retinoic acid-related Orphan Receptor (ROR): connecting sterol metabolism to regulation of the immune system and autoimmune disease.2018
- Author(s)
  Jetten A.M., Takeda Y., and Kang H.S.
- Journal Title
  
  Curr. Opin. Toxicol.
  
  Volume: 8 Issue: 1 Pages: 66-80
- DOI
  10.1038/s41598-017-10202-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12038
[Journal Article] Chemical compound-based direct reprogramming for future clinical applications.2018
- Author(s)
  Takeda Y., Harada Y., Yoshikawa T., Dai P.
- Journal Title
  
  Bioscience Reports
  
  Volume: 38 Issue: 3
- DOI
  10.1042/bsr20171650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15222, KAKENHI-PROJECT-18K12038
[Journal Article] 低分子化合物を用いた再生医療用細胞のダイレクトリプログラミング2018
- Author(s)
  戴平、武田行正
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 127 Pages: 1-12
- NAID
  40021465056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15222
[Journal Article] 低分子化合物を用いた再生医療用細胞のダイレクトリプログラミング2018
- Author(s)
  戴平、武田行正
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 127 Pages: 1-12
- NAID
  40021465056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12038
[Journal Article] Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds.2017
- Author(s)
  Takeda Y., Harada Y., Yoshikawa T., Dai P.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4304-4304
- DOI
  10.1038/s41598-017-04665-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15222
[Journal Article] The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells.2016
- Author(s)
  Kang H.S., Takeda Y., Jeon K., and Jetten A.M.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 6 Pages: e0157138-e0157138
- DOI
  10.1371/journal.pone.0157138
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18546, KAKENHI-PROJECT-16K15222
[Journal Article] Development of a Topical Treatment for Psoriasis Targeting ROR: From Bench to Skin.2016
- Author(s)
  Smith S.H., Peredo C.E., Takeda Y., Bui T., Neil J., Rickard D., Millerman E., Therrien J.P., Nicodeme E., Brusq J.M., Birault V., Viviani F., Hofland H., Jetten A.M., and Cote-Sierra J.
- Journal Title
  
  PLoS One
  
  Volume: 11
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18546
[Presentation] 肥満による脱共役タンパク質UCP1の発現フィードバック制御2023
- Author(s)
  武田行正
- Organizer
  第44回日本肥満学会（仙台）
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 公募シンポジウム：1PS-15「肥満を反映した遊離脂肪酸によるヒト褐色脂肪細胞の恒常的熱産生機構の解明」2023
- Author(s)
  武田行正
- Organizer
  第46回日本分子生物学会年会（神戸）
- Invited
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 一般講演「幹細胞応用」O-11-5　ヒトベージュ細胞モデルを用いた褐色化因子の同定2023
- Author(s)
  武田行正
- Organizer
  第22回日本再生医療学会総会（京都）
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 概日リズムと糖・脂肪代謝、褐色脂肪細胞と食品成分2023
- Author(s)
  武田行正
- Organizer
  福井県立大学生物資源学科特別講演（福井）
- Invited
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 無血清培地を用いた低分子化合物誘導性褐色脂肪細胞ciBAの誘導とそのキャラクタリゼーション2022
- Author(s)
  武田行正
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 新規ヒトベージュ細胞モデルによる褐色化因子の同定2022
- Author(s)
  武田行正
- Organizer
  第３３回小野医学研究財団研究成果発表会
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] ヒトベージュ細胞モデルを用いた褐色化因子の同定2022
- Author(s)
  武田行正
- Organizer
  第２２回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] カプサイシンによるヒト褐色脂肪細胞モデルの褐色化2022
- Author(s)
  武田行正
- Organizer
  第４３回日本肥満学会
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 概日リズムと糖・脂肪代謝、褐色脂肪細胞と食品成分2022
- Author(s)
  武田行正
- Organizer
  福井県立大学生物資源学科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] ワークショップ：1AW-08-2　Capsaicinによる褐色化効果の解明2022
- Author(s)
  武田行正
- Organizer
  第４５回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] 非遺伝子導入型細胞運命変換によるヒト線維芽細胞から機能的な褐色脂肪細胞の誘導2021
- Author(s)
  武田行正
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K12669
[Presentation] シグナル伝達経路制御によるヒト線維芽細胞から褐色脂肪細胞へのダイレクトリプログラミング2018
- Author(s)
  武田行正、原田義規、戴平
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K15222
[Presentation] シグナル伝達経路制御によるヒト線維芽細胞から褐色脂肪細胞へのダイレクトリプログラミング2018
- Author(s)
  武田行正
- Organizer
  第１７回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K12038
[Presentation] Small molecule-based direct reprogramming from human dermal fibroblasts into brown adipocytes.2018
- Author(s)
  Takeda Y., Harada Y., and Dai P.
- Organizer
  5th TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12038
[Presentation] 低分子化合物を用いたダイレクトリプログラミングによるヒト線維芽細胞から褐色脂肪細胞への直接誘導2017
- Author(s)
  武田行正、原田義規、戴平
- Organizer
  第40回日本分子生物学会年会・2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16K15222
[Presentation] レチノイン酸関連オーファン核内受容体RORは脂質代謝に関わる遺伝子の１日における転写を制御する2015
- Author(s)
  武田行正
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会・合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K18546

1. Dai Ping (20291924)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results

Takeda Yukimasa 武田 行正

Yukimasa Takeda 武田 行正

Research Projects

Research Products

Co-Researchers

Development of a novel technology for the proliferation of human brown adipocytes by inducing preadipocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a novel model for human beige adipocytes converted from smooth muscle-like cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of non-transgenetic direct reprogramming method for human neuronal subtypes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Direct reprogramming to desired cell types applicable for regenerative medicine in a transgene-free mannerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reprogramming into induced totipotent stem cells by maternal factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Precision Medicine 研究者の最新動向「ヒト褐色脂肪細胞を用いた褐色化機構の解明」2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 「Precision Medicine」2023年1月号6巻 研究者の最新動向「ヒト褐色脂肪細胞を用いた褐色化機構の解明」2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 「Medical Science Digest」2023年10月号49巻 最先端医療の今「ヒト褐色脂肪細胞モデルを用いたUCP1の発現制御機構の解明」2023

Author(s)

Total Pages

Publisher

Data Source

[Book] Bio Clinica BIOLOGY TOPICS 「ヒト皮膚線維芽細胞から誘導される褐色脂肪細胞とその応用」2022

Author(s)

Total Pages

Publisher

Data Source

[Book] Precision Medicine 研究者の最新動向「ヒト褐色脂肪細胞のケミカルダイレクトリプログラミング」2021

Author(s)

Total Pages

Publisher

Data Source

[Book] Medical Science Digest2021

Author(s)

Total Pages

Publisher

Data Source

[Book] Medical Science Digest2021

Author(s)

Total Pages

Publisher

Data Source

[Book] Medical Science Digest 最先端医療の今「低分子化合物によるヒト褐色脂肪細胞のダイレクトリプログラミング」2021

Author(s)

Total Pages

Publisher

Takeda Yukimasa 武田行正

Yukimasa Takeda 武田行正

[Book] Precision Medicine　研究者の最新動向「ヒト褐色脂肪細胞を用いた褐色化機構の解明」2023

[Book] 「Precision Medicine」2023年1月号6巻　研究者の最新動向「ヒト褐色脂肪細胞を用いた褐色化機構の解明」2023

[Book] 「Medical Science Digest」2023年10月号49巻　最先端医療の今「ヒト褐色脂肪細胞モデルを用いたUCP1の発現制御機構の解明」2023

[Book] Bio Clinica　BIOLOGY TOPICS 「ヒト皮膚線維芽細胞から誘導される褐色脂肪細胞とその応用」2022

[Book] ダイレクトリプログラミング-再生医療の新展開　第２編第６章2020

[Book] ダイレクトリプログラミング-再生医療の新展開　第２編第６章2020