Suetomi Takeshi 末冨建

… Alternative Names

末冨建スエトミタケシ

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Researcher Number	40749842
Other IDs	https://orcid.org/0000-0002-5257-9865
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2023: 山口大学, 大学院医学系研究科, 助教 2021 – 2023: 山口大学, 医学部附属病院, 助教 2019 – 2020: 山口大学, 医学部附属病院, 診療助教(4日/週) 2015: 山口大学, 医学部, 特別医学研究員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / 0902:General internal medicine and related fields / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator インフラマソーム / マクロファージ / HFpEF / 線維化 / カルモジュリン依存キナーゼ / カルモジュリンキナーゼ / 炎症 / 心不全 / 細胞外小胞 / 左室拡張能 … More / リモデリング / 自然炎症 / 心筋リモデリング / 圧負荷 / 慢性炎症 / 心筋細胞 / カルモジュリン依存性キナーゼ / パクリタキセル / 光干渉断層法 / 薬剤溶出バルーン / 冠動脈ステント再狭窄 … More Except Principal Investigator 小胞体Ca制御 / スキャホールド / 光干渉断層法 / 不安定プラーク / 心筋梗塞 Less

カルモジュリンキナーゼを標的とした炎症抑制・線維化抑制による新規心不全治療の探索Principal Investigator
- Principal Investigator
  
  末冨建
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yamaguchi University
心筋梗塞ハイリスク病変に対する血管小胞体Ca制御による新規プラーク安定化療法の開発
- Principal Investigator
  
  岡村誉之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yamaguchi University
Novel treatment for heart failure by inflammasome regulation targeting calcium-calmodulin dependent protein kinase IIPrincipal Investigator
- Principal Investigator
  
  Suetomi Takeshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yamaguchi University
Anti-inflammatory approach targeting calcium/calmodulin-dependent protein kinase as a novel therapeutic strategy to the heart failurePrincipal Investigator
- Principal Investigator
  
  Suetomi Takeshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Yamaguchi University
三次元光干渉断層法を用いた薬剤塗布デバイスの性能評価と治療への応用Principal Investigator
- Principal Investigator
  
  末冨建
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Yamaguchi University

All 2023 2022 2021 2020 2019 2016

All Journal Article Presentation Book

[Book] Medical Science Digest 2022年10月号予防を科学する：炎症細胞社会学 The Science of Prevention: Inflammatory Cell Sociology2022
- Author(s)
  末冨　建ほか
- Total Pages
  55
- Publisher
  北隆館ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K17119
[Journal Article] RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure2023
- Author(s)
  Fujii Shohei、Kobayashi Shigeki、Chang Yaowei、Nawata Junya、Yoshitomi Ryosuke、Tanaka Shinji、Kohno Michiaki、Nakamura Yoshihide、Ishiguchi Hironori、Suetomi Takeshi、Uchinoumi Hitoshi、Oda Tetsuro、Okuda Shinichi、Okamura Takayuki、Yamamoto Takeshi、Yano Masafumi
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 178 Pages: 36-50
- DOI
  10.1016/j.yjmcc.2023.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03677, KAKENHI-PROJECT-20K17119, KAKENHI-PROJECT-21K08128, KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-22K15686
[Journal Article] Stabilizing cardiac ryanodine receptor with dantrolene treatment prevents left ventricular remodeling in pressure-overloaded heart failure mice2023
- Author(s)
  Yano Yasutake、Kobayashi Shigeki、Uchida Tomoyuki、Chang Yaowei、Nawata Junya、Fujii Shohei、Nakamura Yoshihide、Suetomi Takeshi、Uchinoumi Hitoshi、Oda Tetsuro、Yamamoto Takeshi、Yano Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 642 Pages: 175-184
- DOI
  10.1016/j.bbrc.2022.12.063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-21K08128, KAKENHI-PROJECT-22K15686, KAKENHI-PROJECT-20H03677, KAKENHI-PROJECT-20K17119
[Journal Article] Dantrolene improves left ventricular diastolic property in mineralcorticoid-salt-induced hypertensive rats2023
- Author(s)
  Nawata Junya、Yamamoto Takeshi、Tanaka Shinji、Yano Yasutake、Uchida Tomoyuki、Fujii Shohei、Nakamura Yoshihide、Suetomi Takeshi、Uchinoumi Hitoshi、Oda Tetsuro、Kobayashi Shigeki、Yano Masafumi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 34 Pages: 101449-101449
- DOI
  10.1016/j.bbrep.2023.101449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-22K15686, KAKENHI-PROJECT-20H03677, KAKENHI-PROJECT-20K17119, KAKENHI-PROJECT-21K08128
[Journal Article] Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice2022
- Author(s)
  Sakai Chihiro、Mikawa Mei、Yamamoto Takeshi、Uchida Tomoyuki、Nakamura Yoshihide、Akase Hideaki、Suetomi Takeshi、Tominaga Naoomi、Inamitsu Masako、Oda Tetsuro、Okamura Takayuki、Kobayashi Shigeki、Yano Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 623 Pages: 51-58
- DOI
  10.1016/j.bbrc.2022.07.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-21K08128, KAKENHI-PROJECT-22K15686, KAKENHI-PROJECT-20K17119
[Journal Article] Stabilization of RyR2 maintains right ventricular function, reduces the development of ventricular arrhythmias, and improves prognosis in pulmonary hypertension.2022
- Author(s)
  Tanaka S, Yamamoto T, Mikawa M, Nawata J, Fujii S, Nakamura Y, Kato T, Fukuda M, Suetomi T, Uchinoumi H, Oda T, Okuda S, Okamura T, Kobayashi S, Yano M.
- Journal Title
  
  Heart Rhythm.
  
  Volume: S1547 Issue: 6 Pages: 00119-00119
- DOI
  10.1016/j.hrthm.2022.02.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03677, KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-21K08128, KAKENHI-PROJECT-20K17119
[Journal Article] Endoplasmic reticulum stress promotes nuclear translocation of calmodulin, which activates phenotypic switching of vascular smooth muscle cells2022
- Author(s)
  Uchida Tomoyuki、Oda Tetsuro、Yamamoto Takeshi、Inamitsu Masako、Sakai Chihiro、Uchinoumi Hitoshi、Suetomi Takeshi、Nakamura Yoshihide、Okamoto Yoko、Tateda Satomi、Fujii Shohei、Tanaka Shinji、Nawata Junya、Okamura Takayuki、Kobayashi Shigeki、Yano Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 628 Pages: 155-162
- DOI
  10.1016/j.bbrc.2022.08.069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-21K08128, KAKENHI-PROJECT-22K15686, KAKENHI-PROJECT-20H03677, KAKENHI-PROJECT-20K17119
[Journal Article] Inflammation in nonischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling2019
- Author(s)
  Suetomi Takeshi、Miyamoto Shigeki、Joan Heller Brown
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 317 Issue: 5 Pages: H877-H890
- DOI
  10.1152/ajpheart.00223.2019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23969
[Presentation] George E. Brown Memorial Lecture: Mediation of inflammation through Ca2+/ Calmodulin-dependent protein kinase II (CaMKII) in macrophage is essential for pressure overload-induced adverse cardiac remodeling2022
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  American Heart Association Scientific Sessions
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Mediation of inflammation through Ca2+/ Calmodulin-dependent protein kinase II (CaMKII) in macrophage is essential for pressure overload-induced adverse cardiac remodeling2022
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Anti-inflammatory approach targeting CaMKIIδ as a novel therapeutic strategy to the heart failure2022
- Author(s)
  Takeshi Suetomi, Masafumi Yano
- Organizer
  The 5th JCS Council Forum on Basic CardioVascular Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Sterile inflammation through Ca2+/ Calmodulin-dependent protein kinase II (CaMKII) signaling is essential for adverse cardiac remodeling2022
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  International Society for Heart Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Sterile inflammation through Ca2+/ Calmodulin-dependent protein kinase II signaling is essential for adverse cardiac remodeling2022
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  ESC Congress 2021 - European Society of Cardiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Anti-inflammatory approach targeting CaMKIIδ as a novel therapeutic strategy to the heart failure2021
- Author(s)
  Takeshi Suetomi, Masafumi Yano
- Organizer
  The 5th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Sterile inflammation through Ca2+/ Calmodulin-dependent protein kinase II signaling is essential for adverse cardiac remodeling2021
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  European Society of Cardiology Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Sterile inflammation through Ca2+/ Calmodulin-dependent protein kinase II (CaMKII) signaling is essential for adverse cardiac remodeling2021
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  the 38th Annual Scientific Meeting of the Japanese Section of the International Society for Heart Research (ISHR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Sterile Inflammation through Ca2+/ Calmodulin-Dependent Protein Kinase II is Essential for Adverse Cardiac Remodeling2021
- Author(s)
  Takeshi Suetomi, Shinichi Okuda, Yoko Okamoto, Satomi Tateda, Michiaki Kono, Toshiro Kajii, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano.
- Organizer
  The 85th Annual Scientific Meeting of the Japanese Circulation Society (JCS2021)
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Anti-inflammatory approach for heart failure targeting Calcium-Calmodulin dependent protein kinase2020
- Author(s)
  Takeshi Suetomi
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K23969
[Presentation] Sterile Inflammation through CaMKII Signaling in non-ischemic heart failure2020
- Author(s)
  Takeshi Suetomi
- Organizer
  The 4th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Sterile Inflammation through CaMKII Signaling in non-ischemic heart failure2020
- Author(s)
  Takeshi Suetomi
- Organizer
  The 4th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-19K23969
[Presentation] Anti-inflammatory approach for heart failure targeting Calcium-Calmodulin dependent protein kinase2020
- Author(s)
  Takeshi Suetomi
- Organizer
  The 84th Annual Scientific Meeting of the Japanese Circulation Society (JCS2020)
- Data Source
  KAKENHI-PROJECT-20K17119
[Presentation] Calcium/calmodulin-dependent Protein Kinase II (CaMKII) Signaling in Cardiomyocytes Initiates Inflammasome Required for Adverse Cardiac Remodeling in Response to Pressure Overload2019
- Author(s)
  Takeshi Suetomi, Andrew Willeford, Cameron Brand, Shigeki Miyamoto, Joan Heller Brown
- Organizer
  American Heart Association Scientific Sessions 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23969
[Presentation] Correlation between OCT Finding and Tissue Paclitaxel Concentration: Does the OCT Finding work as the predictor of restenosis after DCB?2016
- Author(s)
  Takeshi Suetomi, Takayuki Okamura, Jutaro Yamada, Tetsuro Oda, Mamoru Mochizuki, Tatsuhiro Fujimura, Yosuke Miyazaki, Akihiro Hino, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano
- Organizer
  第80回　日本循環器学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K19380

1. 岡村誉之 (70380011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 南和幸 (00229759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 矢野雅文 (90294628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 山本健 (50363122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 小林茂樹 (90397993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 小田哲郎 (40569290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Suetomi Takeshi 末冨 建

末冨 建 スエトミ タケシ

Research Projects

Research Products

Co-Researchers

カルモジュリンキナーゼを標的とした炎症抑制・線維化抑制による新規心不全治療の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心筋梗塞ハイリスク病変に対する血管小胞体Ca制御による新規プラーク安定化療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel treatment for heart failure by inflammasome regulation targeting calcium-calmodulin dependent protein kinase IIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-inflammatory approach targeting calcium/calmodulin-dependent protein kinase as a novel therapeutic strategy to the heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

三次元光干渉断層法を用いた薬剤塗布デバイスの性能評価と治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Medical Science Digest 2022年10月号 予防を科学する：炎症細胞社会学 The Science of Prevention: Inflammatory Cell Sociology2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stabilizing cardiac ryanodine receptor with dantrolene treatment prevents left ventricular remodeling in pressure-overloaded heart failure mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dantrolene improves left ventricular diastolic property in mineralcorticoid-salt-induced hypertensive rats2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stabilization of RyR2 maintains right ventricular function, reduces the development of ventricular arrhythmias, and improves prognosis in pulmonary hypertension.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endoplasmic reticulum stress promotes nuclear translocation of calmodulin, which activates phenotypic switching of vascular smooth muscle cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammation in nonischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] George E. Brown Memorial Lecture: Mediation of inflammation through Ca2+/ Calmodulin-dependent protein kinase II (CaMKII) in macrophage is essential for pressure overload-induced adverse cardiac remodeling2022

Author(s)

Organizer

Data Source

[Presentation] Mediation of inflammation through Ca2+/ Calmodulin-dependent protein kinase II (CaMKII) in macrophage is essential for pressure overload-induced adverse cardiac remodeling2022

Suetomi Takeshi 末冨建

末冨建スエトミタケシ

[Book] Medical Science Digest 2022年10月号予防を科学する：炎症細胞社会学 The Science of Prevention: Inflammatory Cell Sociology2022