(unregistered) (unregistered) 佐々木永太

… Alternative Names

Sasaki Eita 佐々木永太

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Researcher Number	40762216
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所インフルエンザ研究センター, 主任研究員 2025: 国立健康危機管理研究機構, 国立感染症研究所ワクチン開発研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 主任研究官 2020 – 2021: 国立感染症研究所, 血液・安全性研究部, 主任研究官 2017 – 2018: 国立感染症研究所, 血液・安全性研究部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Medical engineering assessment Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 49050:Bacteriology-related
Keywords	Principal Investigator ワクチン / アジュバント / インフルエンザワクチン / ポックスウイルス / サル痘 / マウス / 天然痘 / エムポックスウイルス / インターフェロン / 呼吸器感染症 … More / 肺 / pDC / インフルエンザウイルス / 経鼻ワクチン / IgA抗体 / 自然免疫 / IgA / 樹状細胞 / 粘膜免疫 / 副反応 / 安全性評価 / 免疫毒性 / 形質細胞様樹状細胞 / バイオマーカー / PBMC / 安全性評価系 … More Except Principal Investigator 粘膜免疫 / ワクチン / 歯周病 / 細菌膜小胞 / 細菌由来膜小胞 / 膜小胞 / 経鼻投与 / CpG / 結核ワクチン / BCG / 遅延型過敏反応 / 結核 / インターフェロンアルファ / CpG-ODN / アジュバント Less

広域感染防御を誘導する免疫抗原とアジュバントを駆使した次世代天然痘ワクチンの開発Principal Investigator
- Principal Investigator
  
  佐々木永太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
天然型CpG DNAを取り入れたBCG免疫を賦活する経鼻結核ワクチンの開発基盤
- Principal Investigator
  
  前山順一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Acceleration of unexplored periodontal disease vaccine development by intranasal administration of bacterial membrane vesicles
- Principal Investigator
  
  中尾龍馬
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  National Institute of Infectious Diseases
Identification and functional elucidation of a novel dendritic cell subset that induces efficient IgA production by nasal vaccinePrincipal Investigator
- Principal Investigator
  
  Sasaki Eita
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Establishment of in vitro evaluation system for vaccine and adjuvant safetyPrincipal Investigator
- Principal Investigator
  
  Sasaki Eita
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical engineering assessment
- Research Institution
  National Institute of Infectious Diseases

All 2023 2022 2021 2020 2018 2017

All Journal Article Presentation Book

[Book] 「Influenza Therapeutics and Challenges」2018,p113-p130 Genomic Approaches Enable Evaluation of the Safety and Quality of Influenza Vaccines and Adjuvants.2018
- Author(s)
  Eita Sasaki, Takuo Mizukami, Isao Hamaguchi
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-17K13046
[Book] 感染症ワクチンおよびアジュバントのレギュレーションと評価法-「感染症ワクチンおよびアジュバントのレギュレーションと評価法」p349-p3542017
- Author(s)
  佐々木永太、水上拓郎、浜口功
- Total Pages
  355
- Publisher
  シーエムシー出版
- ISBN
  9784781312385
- Data Source
  KAKENHI-PROJECT-17K13046
[Journal Article] Systemically inoculated adjuvants stimulate pDC-dependent IgA response in local site2023
- Author(s)
  Sasaki Eita、Asanuma Hideki、Momose Haruka、Furuhata Keiko、Mizukami Takuo、Matsumura Takayuki、Takahashi Yoshimasa、Hamaguchi Isao
- Journal Title
  
  Mucosal Immunology
  
  Volume: - Issue: 3 Pages: 275-286
- DOI
  10.1016/j.mucimm.2023.03.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07545, KAKENHI-PROJECT-22K12901, KAKENHI-PROJECT-20K16269
[Journal Article] Scanning Electron Microscopy of Escherichia coli Encapsulated in a Spacerized Graphene Sandwich2022
- Author(s)
  Sasaki, Yuki; Hirayama, Satoru; Nakao, Ryoma
- Journal Title
  
  Microscopy
  
  Volume: in press Issue: 3 Pages: 175-180
- DOI
  10.1093/jmicro/dfac010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22644, KAKENHI-PROJECT-20H03861, KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164, KAKENHI-PROJECT-19K15404
[Journal Article] A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles2022
- Author(s)
  Nakao Ryoma、Kobayashi Hirotaka、Iwabuchi Yusuke、Kawahara Kazuyoshi、Hirayama Satoru、Ramstedt Madeleine、Sasaki Yuki、Kataoka Michiyo、Akeda Yukihiro、Ohnishi Makoto
- Journal Title
  
  npj Vaccines
  
  Volume: 7 Issue: 1 Pages: 13-13
- DOI
  10.1038/s41541-022-00572-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-22K20988, KAKENHI-PROJECT-21KK0164, KAKENHI-PROJECT-19K15404
[Journal Article] Nasal alum-adjuvanted vaccine promotes IL-33 release from alveolar epithelial cells that elicits IgA production via type 2 immune responses2021
- Author(s)
  Sasaki E, Asanuma H, Momose H, Furuhata K, Mizukami T, Hamaguchi I.
- Journal Title
  
  PLoS Pathog
  
  Volume: 17 Issue: 8 Pages: e1009890-e1009890
- DOI
  10.1371/journal.ppat.1009890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12873, KAKENHI-PROJECT-20K16269
[Journal Article] Pharmacodynamic and safety considerations for influenza vaccine and adjuvant design2020
- Author(s)
  Eita Sasaki, Isao Hamaguchi, Takuo Mizukami
- Journal Title
  
  Expert Opinion on Drug Metabolism & Toxicology.
  
  Volume: 16(11) Issue: 11 Pages: 1051-1061
- DOI
  10.1080/17425255.2020.1807936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12873, KAKENHI-PROJECT-20K16269
[Journal Article] Immunogenicity and Toxicity of Different Adjuvants Can Be Characterized by Profiling Lung Biomarker Genes After Nasal Immunization2020
- Author(s)
  Eita Sasaki, Hideki Asanuma, Haruka Momose, Keiko Furuhata, Takuo Mizukami, Isao Hamaguchi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1-19
- DOI
  10.3389/fimmu.2020.02171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12873, KAKENHI-PROJECT-20K16269
[Journal Article] In vitro marker gene expression analyses in human peripheral blood mononuclear cells: A tool to assess safety of influenza vaccines in humans2018
- Author(s)
  Sasaki Eita、Momose Haruka、Hiradate Yuki、Ishii Ken J.、Mizukami Takuo、Hamaguchi Isao
- Journal Title
  
  Journal of Immunotoxicology
  
  Volume: 15 Issue: 1 Pages: 53-62
- DOI
  10.1080/1547691x.2018.1447052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K13046
[Journal Article] Establishment of a novel safety assessment method for vaccine adjuvant development2018
- Author(s)
  Sasaki Eita、Momose Haruka、Hiradate Yuki、Mizukami Takuo、Hamaguchi Isao
- Journal Title
  
  Vaccine
  
  Volume: 36 Issue: 46 Pages: 7112-7118
- DOI
  10.1016/j.vaccine.2018.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13046
[Presentation] Systemically inoculated adjuvants stimulate pDC-dependent IgA response in local site.2023
- Author(s)
  Eita Sasaki
- Organizer
  日米医学協力計画汎太平洋新興・再興感染症(EID)国際会議
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16269
[Presentation] 外来性莢膜多糖を発現するプロバイオティクス大腸菌が作る膜小胞ワクチンの特性評価2021
- Author(s)
  Ryoma Nakao, Hiroaki Kobayashi, Yusuke Iwabuchi, Yusuke Sasaki, Madeleine Ramstedt, Satoru Hirayama, Makoto Ohnishi
- Organizer
  第15回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 遺伝子マーカーを用いたアジュバント含有経鼻ワクチンの細胞傷害性と有効性評価2020
- Author(s)
  佐々木　永太、浅沼秀樹、百瀬　暖佳、古畑　啓子、水上　拓郎、浜口功
- Organizer
  日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K16269
[Presentation] ヒトPBMCと末梢血ヒト化マウスを用いたワクチンの安全性評価とアジュバント開発への応用2018
- Author(s)
  佐々木永太、百瀬暖佳、浅沼秀樹、古畑啓子、水上拓郎、浜口功
- Organizer
  第25回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K13046
[Presentation] マーカー遺伝子と統計学的手法を用いた新規アジュバント安全性評価系の構築2017
- Author(s)
  佐々木永太, 百瀬暖佳, 平舘裕希, 古畑啓子, 山田宏, 石井健, 水上拓郎, 浜口功
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K13046
[Presentation] ワクチン接種時の初期免疫反応を捉えるヒト化マウスモデルの作出ならびにワクチン安全性評価法への応用とその評価2017
- Author(s)
  佐々木永太、百瀬暖佳、平舘裕希、古畑啓子、水上拓郎、浜口功
- Organizer
  第24回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K13046

1. 前山順一 (40199641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 井坂雅徳 (40336673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中尾龍馬 (10370959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 相内章 (10572133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 泉福英信 (20250186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 野村暢彦 (60292520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 井上智 (90213157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山口雄大 (40726080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 水上拓郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 高橋宜聖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 平山悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

(unregistered) (unregistered) 佐々木 永太

Sasaki Eita 佐々木 永太

Research Projects

Research Products

Co-Researchers

広域感染防御を誘導する免疫抗原とアジュバントを駆使した次世代天然痘ワクチンの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

天然型CpG DNAを取り入れたBCG免疫を賦活する経鼻結核ワクチンの開発基盤

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Acceleration of unexplored periodontal disease vaccine development by intranasal administration of bacterial membrane vesicles

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional elucidation of a novel dendritic cell subset that induces efficient IgA production by nasal vaccinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of in vitro evaluation system for vaccine and adjuvant safetyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「Influenza Therapeutics and Challenges」2018,p113-p130 Genomic Approaches Enable Evaluation of the Safety and Quality of Influenza Vaccines and Adjuvants.2018

Author(s)

Publisher

Data Source

[Book] 感染症ワクチンおよびアジュバントのレギュレーションと評価法-「感染症ワクチンおよびアジュバントのレギュレーションと評価法」p349-p3542017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Systemically inoculated adjuvants stimulate pDC-dependent IgA response in local site2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Scanning Electron Microscopy of Escherichia coli Encapsulated in a Spacerized Graphene Sandwich2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nasal alum-adjuvanted vaccine promotes IL-33 release from alveolar epithelial cells that elicits IgA production via type 2 immune responses2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacodynamic and safety considerations for influenza vaccine and adjuvant design2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunogenicity and Toxicity of Different Adjuvants Can Be Characterized by Profiling Lung Biomarker Genes After Nasal Immunization2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro marker gene expression analyses in human peripheral blood mononuclear cells: A tool to assess safety of influenza vaccines in humans2018

Author(s)

Journal Title

DOI

Data Source

(unregistered) (unregistered) 佐々木永太

Sasaki Eita 佐々木永太