ONO TAKEHITO 小野岳人

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ONO Takehito 小野岳人

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Researcher Number	40772471
Other IDs	https://orcid.org/0000-0003-2445-4253
Affiliation (Current)	2025: 岡山理科大学, 獣医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 岡山理科大学, 獣医学部, 講師 2018 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 57070:Developmental dentistry-related / Basic Section 57010:Oral biological science-related
Keywords	Principal Investigator 運動器科学 / 破骨細胞 / 骨芽細胞 / 筋 / 骨 / メカニカルストレス / 骨代謝 / 歯根膜 / 骨吸収 / バイオメカニクス … More / 矯正歯科治療 / 骨代謝学 / 歯根膜細胞 / 骨細胞 / 骨免疫学 / 歯科矯正学 / 筋細胞 / 咀嚼運動 / 口腔機能 / 筋代謝 / 咀嚼 Less

Health promotion by locomomimetismPrincipal Investigator
- Principal Investigator
  
  小野岳人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Okayama University of Science
Analyses of the mechanism underlying alveolar bone remodeling from the viewpoint of mechanobiology of the periodontal ligamentPrincipal Investigator
- Principal Investigator
  
  Ono Takehito
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tokyo Medical and Dental University
Regulation of locomotor tissues in the maxillofacial region under mechanical stimuliPrincipal Investigator
- Principal Investigator
  
  ONO Takehito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokyo Medical and Dental University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] Encyclopedia of Bone Biology 1st Edition (分担執筆)2020
- Author(s)
  Mikihito Hayashi, Takehito Ono, and Tomoki Nakashima
- Total Pages
  2374
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-18K17014
[Book] 運動器産生分子がつなぐ臓器連環と動的恒常性2019
- Author(s)
  中島友紀, 小野岳人, 林幹人
- Total Pages
  213
- Publisher
  羊土社
- ISBN
  9784758103787
- Data Source
  KAKENHI-PROJECT-18K17014
[Journal Article] Bone remodeling induced by mechanical force during orthodontic treatment2023
- Author(s)
  Ono Takehito
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 158 Issue: 3 Pages: 258-262
- DOI
  10.1254/fpj.22110
- ISSN
  0015-5691, 1347-8397
- Year and Date
  2023-05-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21K17154
[Journal Article] The interleukin-6 signal regulates orthodontic tooth movement and pain2023
- Author(s)
  Toyama Naomi、Ono Takehito、Ono Takashi、Nakashima Tomoki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 684 Pages: 149068-149068
- DOI
  10.1016/j.bbrc.2023.09.096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17154, KAKENHI-PROJECT-20H00551
[Journal Article] 骨粗鬆症における骨代謝回転2023
- Author(s)
  小野岳人, 中島友紀
- Journal Title
  
  日本臨牀
  
  Volume: 81 Pages: 58-63
- Data Source
  KAKENHI-PROJECT-21K17154
[Journal Article] 骨のメカノバイオロジー2023
- Author(s)
  小野岳人, 中島友紀
- Journal Title
  
  BIO Clinica
  
  Volume: 38 Pages: 21-25
- Data Source
  KAKENHI-PROJECT-21K17154
[Journal Article] Oral bone biology2022
- Author(s)
  Ono Takehito、Nakashima Tomoki
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 64 Issue: 1 Pages: 8-17
- DOI
  10.1016/j.job.2022.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17154, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-21K19554
[Journal Article] Simultaneous augmentation of muscle and bone by locomomimetism through calcium-PGC-1α signaling2022
- Author(s)
  Ono Takehito、Denda Ryosuke、Tsukahara Yuta、Nakamura Takashi、Okamoto Kazuo、Takayanagi Hiroshi、Nakashima Tomoki
- Journal Title
  
  Bone Research
  
  Volume: 10 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41413-022-00225-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17154, KAKENHI-PROJECT-21H05046, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-21K19554, KAKENHI-PROJECT-23K24454
[Journal Article] 【フレイル対策;骨と骨格筋からの心身の健康】骨による心身の健康の維持2021
- Author(s)
  小野岳人, 中島友紀
- Journal Title
  
  FOOD Style 21
  
  Volume: 25 Pages: 34-38
- Data Source
  KAKENHI-PROJECT-21K17154
[Journal Article] Identification of a KLF5-dependent program and drug development for skeletal muscle atrophy2021
- Author(s)
  Liu L, Koike H, Ono T, Hayashi S, Kudo F, Kaneda A, Kagechika H, Manabe I, Nakashima T, Oishi, Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 118 Issue: 35
- DOI
  10.1073/pnas.2102895118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03679, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-20H04938, KAKENHI-PUBLICLY-20H04956, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-19H03648, KAKENHI-PROJECT-21H03331, KAKENHI-PROJECT-21K06961, KAKENHI-PROJECT-21K19554, KAKENHI-PROJECT-21K17154
[Journal Article] RANKL biology: bone metabolism, the immune system, and beyond2020
- Author(s)
  Ono Takehito、Hayashi Mikihito、Sasaki Fumiyuki、Nakashima Tomoki
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 40 Issue: 1
- DOI
  10.1186/s41232-019-0111-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17014
[Journal Article] 顎口腔系におけるメカニカルストレス2020
- Author(s)
  小野岳人, 中島友紀
- Journal Title
  
  口腔病学会雑誌
  
  Volume: 87 Pages: 9-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17014
[Journal Article] The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR42020
- Author(s)
  Tsuchiya Yosuke、Hayashi Mikihito、Nagamatsu Katashi、Ono Takehito、Kamakura Masaki、Iwata Takanori、Nakashima Tomoki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 34 Pages: 12224-12232
- DOI
  10.1074/jbc.ra120.013821
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23020, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-18K17014
[Journal Article] The regulation of RANKL by mechanical force2020
- Author(s)
  Sasaki Fumiyuki、Hayashi Mikihito、Ono Takehito、Nakashima Tomoki
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 39 Issue: 1 Pages: 34-44
- DOI
  10.1007/s00774-020-01145-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17014, KAKENHI-PROJECT-19K18452
[Journal Article] 矯正歯科治療における骨リモデリング2019
- Author(s)
  小野岳人、中島友紀
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 48(6)
- NAID
  40021950279
- Data Source
  KAKENHI-PROJECT-18K17014
[Journal Article] Forceful mastication activates osteocytes and builds a stout jawbone2019
- Author(s)
  Masamu Inoue、Takehito Ono、Yoshitaka Kameo、Fumiyuki Sasaki、Takashi Ono、Taiji Adachi、Tomoki Nakashima
- Journal Title
  
  Scientific Reports
  
  Volume: 9(1) Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-019-40463-3
- NAID
  120006773166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17014, KAKENHI-PROJECT-16H05506, KAKENHI-PROJECT-16K17980
[Journal Article] Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation2018
- Author(s)
  Kim Yusoon、Hayashi Mikihito、Ono Takehito、Yoda Tetsuya、Takayanagi Hiroshi、Nakashima Tomoki
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 1 Pages: 1-8
- DOI
  10.1080/14397595.2018.1553266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17014, KAKENHI-PROJECT-16H05506, KAKENHI-PROJECT-15H05703
[Presentation] 骨が心を守るメカニズムの解明2023
- Author(s)
  小野岳人
- Organizer
  第41回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] IL-6シグナルは矯正歯科治療における歯の動きと痛みを制御する2023
- Author(s)
  外山奈緒美 , 小野岳人 , 小野卓史 , 中島友紀
- Organizer
  第88回口腔病学会
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] IL-6シグナルは矯正歯科治療における歯の動きと痛みを制御する2023
- Author(s)
  外山奈緒美 , 小野岳人 , 中島友紀 , 小野卓史
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] 骨や筋の強化を介した全身の健康の向上の可能性2023
- Author(s)
  小野岳人
- Organizer
  第41回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] IL-6 regulates orthodontic tooth movement and pain2023
- Author(s)
  Takehito Ono , Naomi Toyama , Takashi Ono , Tomoki Nakashima
- Organizer
  The 71st Annual Meeting of Japanese Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] Augmentation of musculoskeletal tissues by locomomimetism2023
- Author(s)
  Takehito Ono
- Organizer
  The 19th Bone Biology Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] 進行性骨化性線維異形成症(FOP)における異所性骨化発生メカニズムの解析2022
- Author(s)
  尹文強, 寺島明日香, 岡本一男, 小野岳人, 高柳広
- Organizer
  日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] 運動模倣薬LAMZによる筋と骨の強化2022
- Author(s)
  小野岳人, 傳田良亮, 塚原悠太, 中村貴, 岡本一男, 高柳広, 中島友紀
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] Osteocyte RANKL and Mechanical Stress2022
- Author(s)
  小野岳人
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] Analysis of the mechanism of heterotopic ossification and immune response in fibrodysplasia ossificans progressiva(FOP)2022
- Author(s)
  Terashima Asuka, Yin Wengqiang, Okamoto Kazuo, Ono Takehito, Takayanagi Hiroshi
- Organizer
  日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K17154
[Presentation] 咀嚼による脳機能制御機構を運動器科学の視点から再考する2020
- Author(s)
  小野岳人
- Organizer
  第62回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 外傷誘導性異所性骨化モデルマウスの確立2019
- Author(s)
  尹文強, 岡本一男, 寺島明日香, 小野岳人, 高柳広
- Organizer
  第5回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 骨細胞による顎骨リモデリング制御2019
- Author(s)
  小野岳人
- Organizer
  口腔器官の再構築から器官の発生・再生の統一原理の解明 2018年度セミナーシリーズ
- Invited
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 咀嚼強化は骨細胞のサイトカインバランスを調節し頑強な顎骨を形造る2019
- Author(s)
  小野岳人, 井上雅, 佐々木文之, 中島友紀
- Organizer
  第5回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 咀嚼強化は骨細胞のサイトカインバランスを調節し頑強な顎骨を形造る2019
- Author(s)
  小野岳人、井上維、佐々木文之、中島友紀
- Organizer
  日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 非受容体型チロシンキナーゼHck阻害剤は炎症に関連した骨破壊を抑制する2019
- Author(s)
  林幹人, 金裕純, 小野岳人, 高柳広, 中島友紀
- Organizer
  第5回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 成長期の咀嚼強化が下顎骨に与える影響の解析2019
- Author(s)
  井上維, 小野岳人, 中島友紀, 小野卓史
- Organizer
  第78回東京矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 骨補填材料に求められる免疫学的要件2019
- Author(s)
  小野岳人
- Organizer
  第41回日本バイオマテリアル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K17014
[Presentation] 成長期の咀嚼強化が下顎骨に与える影響の解析2018
- Author(s)
  井上維、小野岳人、中島友紀、小野卓史
- Organizer
  日本矯正歯科学会
- Data Source
  KAKENHI-PROJECT-18K17014

1. 大石由美子

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# of Collaborated Products: 1 results
2. 土谷洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ONO TAKEHITO 小野 岳人

ONO Takehito 小野 岳人

Research Projects

Research Products

Co-Researchers

Health promotion by locomomimetismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of the mechanism underlying alveolar bone remodeling from the viewpoint of mechanobiology of the periodontal ligamentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of locomotor tissues in the maxillofacial region under mechanical stimuliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Encyclopedia of Bone Biology 1st Edition (分担執筆)2020

Author(s)

Total Pages

Publisher

Data Source

[Book] 運動器産生分子がつなぐ臓器連環と動的恒常性2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Bone remodeling induced by mechanical force during orthodontic treatment2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] The interleukin-6 signal regulates orthodontic tooth movement and pain2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 骨粗鬆症における骨代謝回転2023

Author(s)

Journal Title

Data Source

[Journal Article] 骨のメカノバイオロジー2023

Author(s)

Journal Title

Data Source

[Journal Article] Oral bone biology2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous augmentation of muscle and bone by locomomimetism through calcium-PGC-1α signaling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 【フレイル対策;骨と骨格筋からの心身の健康】骨による心身の健康の維持2021

Author(s)

Journal Title

Data Source

[Journal Article] Identification of a KLF5-dependent program and drug development for skeletal muscle atrophy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RANKL biology: bone metabolism, the immune system, and beyond2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 顎口腔系におけるメカニカルストレス2020

ONO TAKEHITO 小野岳人

ONO Takehito 小野岳人