Hashimoto Taiki 橋本大輝

Researcher Number	40773875
Other IDs	https://orcid.org/0000-0003-3148-9243
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師 2025: 国立研究開発法人国立がん研究センター, 中央病院, 医員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立がん研究センター, 中央病院, 医員 2017 – 2022: 国立研究開発法人国立がん研究センター, 中央病院, 医員 2016: 国立研究開発法人国立がん研究センター, 中央病院, がん専門修練医
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Human pathology
Keywords	Principal Investigator 大腸癌 / WNT / 鋸歯状病変 / 遺伝子 / Wntシグナル / carcinogenesis / RSPO / 分子病理学 / R-spondin / 臨床 … More / ゲノム / 病理学 / MLH1 / RNF43 / 癌 / SSA/P / 大腸腫瘍 Less

R-spondin依存性大腸癌の全体像の解明Principal Investigator
- Principal Investigator
  
  橋本大輝
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
Clinicopathological analysis of RSPO fusion-positive colorectal carcinomaPrincipal Investigator
- Principal Investigator
  
  Hashimoto Taiki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
Analysis of WNT pathway gene alteration in colorectal serrated lesionsPrincipal Investigator
- Principal Investigator
  
  Hashimoto Taiki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
Pathways of colorectal carcinogenesis from serrated lesions (especially from traditional serrated adenomas).Principal Investigator
- Principal Investigator
  
  Hashimoto Taiki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Japan

All 2022 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer2022
- Author(s)
  Hashimoto T.、Takayanagi D.、Yonemaru J.、Naka T.、Nagashima K.、Yatabe Y.、Shida D.、Hamamoto R.、Kleeman S. O.、Leedham S. J.、Maughan T.、Takashima A.、Shiraishi K. and Sekine S.
- Journal Title
  
  Br J Cancer
  
  Volume: 127 Issue: 6 Pages: 1043-1050
- DOI
  10.1038/s41416-022-01880-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-20K07382
[Journal Article] Acquisition of WNT Pathway Gene Alterations Coincides With the Transition From Precursor Polyps to Traditional Serrated Adenomas.2019
- Author(s)
  Hashimoto T, Ogawa R, Yoshida H, Taniguchi H, Kojima M, Saito Y, Sekine S.
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 43 Issue: 1 Pages: 132-139
- DOI
  10.1097/pas.0000000000001149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07035, KAKENHI-PROJECT-18K15109
[Journal Article] EIF3E‐RSPO2 and PIEZO1‐RSPO2 fusions in colorectal traditional serrated adenoma2019
- Author(s)
  Hashimoto Taiki、Ogawa Reiko、Yoshida Hiroshi、Taniguchi Hirokazu、Kojima Motohiro、Saito Yutaka、Sekine Shigeki
- Journal Title
  
  Histopathology
  
  Volume: 印刷中 Issue: 2 Pages: 266-273
- DOI
  10.1111/his.13867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15109, KAKENHI-PROJECT-18K07035
[Journal Article] Superficially serrated adenoma: a proposal for a novel subtype of colorectal serrated lesion2018
- Author(s)
  Hashimoto T, Tanaka Y, Ogawa R, Mori T, Yoshida H, Taniguchi H, Hiraoka N, Kojima M, Oono Y, Saito Y, Sekine S.
- Journal Title
  
  Modern Pathology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19097
[Journal Article] WNT Pathway Gene Mutations Are Associated With the Presence of Dysplasia in Colorectal Sessile Serrated Adenoma/Polyps2017
- Author(s)
  Hashimoto Taiki、Yamashita Satoshi、Yoshida Hiroshi、Taniguchi Hirokazu、Ushijima Toshikazu、Yamada Tesshi、Saito Yutaka、Ochiai Atsushi、Sekine Shigeki、Hiraoka Nobuyoshi
- Journal Title
  
  The American Journal of Surgical Pathology
  
  Volume: 41 Issue: 9 Pages: 1188-1197
- DOI
  10.1097/pas.0000000000000877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08711, KAKENHI-PROJECT-16K19097
[Journal Article] WNT pathway gene mutations are associated with the presence of dysplasia in colorectal sessile serrated adenoma/polyps2017
- Author(s)
  Taiki Hashimoto, Satoshi Yamashita, Hiroshi Yoshida, Hirokazu Taniguchi, Toshikazu Ushijima, Tesshi Yamada, Yutaka Saito, Atsushi Ochiai, Shigeki Sekine, and Nobuyoshi Hiraoka
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K19097
[Presentation] 鋸歯状腺腫におけるEIF3E-RSPO2およびPIEZO1-RSPO2融合遺伝子の同定2020
- Author(s)
  橋本大輝, 小川玲子, 吉田裕, 谷口浩和, 小嶋基寛, 斎藤豊, 関根茂樹
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15109
[Presentation] WNT経路遺伝子異常の獲得は前駆病変から鋸歯状腺腫への進展に伴う2019
- Author(s)
  橋本大輝、小川玲子、吉田裕、谷口浩和、小嶋基寛、斎藤豊、関根茂樹
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15109
[Presentation] 大腸鋸歯状病変の分子病理学的解析2019
- Author(s)
  橋本大輝
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15109
[Presentation] Superficially serrated adenoma：大腸鋸歯状病変の新たなサブタイプの提案2019
- Author(s)
  橋本大輝, 田中優作, 森泰昌, 吉田裕, 谷口浩和, 平岡伸介, 小嶋基寛, 大野康寛, 斎藤豊, 関根茂樹
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15109
[Presentation] 大腸鋸歯状病変の分子病理学的解析2019
- Author(s)
  橋本大輝
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15109
[Presentation] Superficially serrated adenoma：大腸鋸歯状病変の新たなサブタイプの提案2019
- Author(s)
  橋本大輝、田中優作、森泰昌、吉田裕、谷口浩和、平岡伸介、小嶋基寛、大野康寛、斎藤豊、関根茂樹
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15109
[Presentation] Dysplasiaを伴う大腸SSA/PにおけるWNT関連遺伝子変異2017
- Author(s)
  橋本大輝、山下聡、吉田裕、谷口浩和、牛島俊和、山田哲司、斎藤豊、落合淳志、関根茂樹、平岡伸介
- Organizer
  第106回日本病理学会
- Data Source
  KAKENHI-PROJECT-16K19097
[Presentation] Dysplasia を伴う大腸 SSA/P における WNT 関連遺伝子変異2017
- Author(s)
  橋本大輝
- Organizer
  第 106回日本病理学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2017-04-27
- Data Source
  KAKENHI-PROJECT-16K19097

1. KOJIMA Motohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 関根茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 加島淳平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 谷田部恭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Taiki 橋本 大輝

Research Projects

Research Products

Co-Researchers

R-spondin依存性大腸癌の全体像の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinicopathological analysis of RSPO fusion-positive colorectal carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of WNT pathway gene alteration in colorectal serrated lesionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathways of colorectal carcinogenesis from serrated lesions (especially from traditional serrated adenomas).Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acquisition of WNT Pathway Gene Alterations Coincides With the Transition From Precursor Polyps to Traditional Serrated Adenomas.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EIF3E‐RSPO2 and PIEZO1‐RSPO2 fusions in colorectal traditional serrated adenoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Superficially serrated adenoma: a proposal for a novel subtype of colorectal serrated lesion2018

Author(s)

Journal Title

Data Source

[Journal Article] WNT Pathway Gene Mutations Are Associated With the Presence of Dysplasia in Colorectal Sessile Serrated Adenoma/Polyps2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WNT pathway gene mutations are associated with the presence of dysplasia in colorectal sessile serrated adenoma/polyps2017

Author(s)

Journal Title

Data Source

[Presentation] 鋸歯状腺腫におけるEIF3E-RSPO2およびPIEZO1-RSPO2融合遺伝子の同定2020

Author(s)

Organizer

Data Source

[Presentation] WNT経路遺伝子異常の獲得は前駆病変から鋸歯状腺腫への進展に伴う2019

Author(s)

Organizer

Data Source

[Presentation] 大腸鋸歯状病変の分子病理学的解析2019

Author(s)

Organizer

Data Source

[Presentation] Superficially serrated adenoma：大腸鋸歯状病変の新たなサブタイプの提案2019

Author(s)

Organizer

Data Source

[Presentation] 大腸鋸歯状病変の分子病理学的解析2019

Author(s)

Organizer

Data Source

[Presentation] Superficially serrated adenoma：大腸鋸歯状病変の新たなサブタイプの提案2019

Author(s)

Organizer

Data Source

Hashimoto Taiki 橋本大輝