YAMASAKI Tomohiro 山崎友裕

… Alternative Names

Yamasaki Tomohiro 山崎友裕

山崎友裕ヤマサキトモヒロ

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Researcher Number	40781050
Other IDs	https://orcid.org/0000-0002-9858-9049
Affiliation (Current)	2025: 浜松医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 浜松医科大学, 医学部, 助教 2018 – 2019: 浜松医科大学, 医学部附属病院, 助教 2016 – 2017: 浜松医科大学, 医学部附属病院, 診療助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Tumor therapeutics Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Medium-sized Section 48:Biomedical structure and function and related fields / Surgical dentistry
Keywords	Principal Investigator 脳腫瘍学 / Muse細胞 / PET / 脂肪滴 / 悪性転化 / Stearoyl CoA desaturase / IDH変異神経膠腫 / HSVtk遺伝子 / glioma / 自殺遺伝子幹細胞療法 … More / HSVtk / HSVtk幹細胞 / 生体モニタリング / ガンシクロビル / 単純ヘルペスチミジンキナーゼ / 遺伝子細胞治療 / 自殺遺伝子療法 / 自殺遺伝子細胞療法 / FHBG … More Except Principal Investigator 脳動脈瘤 / 中枢神経 / 浸潤 / PDX / 遺伝子細胞治療 / TK/GCV / SHED / PDXモデル / 自殺遺伝子治療 / 脳腫瘍 / 乳児歯髄幹細胞 / 腫瘍溶解ウイルス / マウス脳動脈瘤モデル / SCD1 / フェロトーシス / 脂肪酸代謝 / 脳血管障害学 / 動物モデル / クモ膜下出血 / エストロゲン / エストロゲン受容体β / 腸内細菌 / 植物性エストロゲン / 自殺遺伝子療法 / 脳腫瘍学 / HSVtk/GCV system / エピソーマルベクター / HSVtk / non-viral vector / ＰｉｇｇｙＢａｃ　system / HSVｔｋ/GCV　ｓｙｓｔｅｍ / 自殺遺伝子幹細胞療法 Less

The role of lipid metabolism in the development of intracranial aneurysm formation and rupture.
- Principal Investigator
  
  神尾佳宣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hamamatsu University School of Medicine
中枢神経系リンパ膜構造の実態と関連疾患病態の解明
- Principal Investigator
  
  山岸覚
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Hamamatsu University School of Medicine
New phase of brain tumor therapy: development of gene and cell therapy with SHED
- Principal Investigator
  
  黒住和彦
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hamamatsu University School of Medicine
細胞小器官脂質解析によるIDH変異神経膠腫の悪性化機序の解明と治療標的分子の探索Principal Investigator
- Principal Investigator
  
  山崎友裕
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hamamatsu University School of Medicine
Treatment strategy using Multilineage-differentiating stress-enduring (Muse) cells transduced with HSVtk gene monitored by in vivo Positron Emission Tomography imaging in mouse glioma modelsPrincipal Investigator
- Principal Investigator
  
  Yamasaki Tomohiro
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
自殺遺伝子幹細胞療法による口腔扁平上皮癌新規治療戦略
- Principal Investigator
  
  山崎佳寿美
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hamamatsu University School of Medicine
Dietary Phytoestrogen Reduces Intracranial Aneurysm Formation in Ovariectomized Female Mice
- Principal Investigator
  
  Hiramatsu Hisaya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
HSVｔｋ遺伝子導入Muse細胞の生体モニタリングと安全性の検証Principal Investigator
- Principal Investigator
  
  山崎友裕
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Tumor therapeutics
- Research Institution
  Hamamatsu University School of Medicine
Development of suicide gene stem cell therapy by non-viral gene transfer method and application to glioma therapy
- Principal Investigator
  
  sameshima tetsuro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine

All 2023 2022 2018 2017 2016

All Journal Article Presentation

[Journal Article] Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study2023
- Author(s)
  Yamasaki Fumiyuki、Fudaba Hirotaka、Asano Kenichiro、(著者省略)、Yasutomo Momii、Kawasaki Yukari、Kakuta Kiyohide、Katayama Kosuke、Tanaka Kazuhiro、Nagashima Hiroaki、Tsukamoto Yoshihiro、Ideguchi Makoto、Nishizaki Takafumi、Kurozumi Kazuhiko、Hosoya Tomohiro、Akita Tomoyuki、Kambe Atsushi
- Journal Title
  
  BMJ Open
  
  Volume: 13 Issue: 4 Pages: e071350-e071350
- DOI
  10.1136/bmjopen-2022-071350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16663, KAKENHI-PROJECT-22K09284, KAKENHI-PROJECT-23K08520, KAKENHI-PROJECT-23K27710
[Journal Article] Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth2023
- Author(s)
  Horikawa M, Koizumi S, Oishi T, Yamamoto T, Ikeno M, Ito M, Yamasaki T, Amano S, Sameshima T, Mitani Y, Otani Y, Yan Y, Suzuki T, Namba H, Kurozumi K
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 30 Issue: 1 Pages: 85-95
- DOI
  10.1038/s41417-022-00527-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07289, KAKENHI-PROJECT-19K07761, KAKENHI-PROJECT-20K09325, KAKENHI-PROJECT-21K20803, KAKENHI-PROJECT-17K10861
[Journal Article] Migration Capacity of Stem Cells from Human Exfoliated Deciduous Teeth Towards Glioma2022
- Author(s)
  Yamamoto Taisuke、Koizumi Shinichiro、Oishi Tomoya、Horikawa Makoto、Asakawa Tetsuya、Yamasaki Tomohiro、Sameshima Tetsuro、Mitani Yasuyuki、Namba Hiroki、Kurozumi Kazuhiko
- Journal Title
  
  Journal of Integrative Neuroscience
  
  Volume: 22 Issue: 1 Pages: 1-1
- DOI
  10.31083/j.jin2201001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09325, KAKENHI-PROJECT-17K10861
[Journal Article] Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases2022
- Author(s)
  Oishi Tomoya、Ito Masahiko、Koizumi Shinichiro、Horikawa Makoto、Yamamoto Taisuke、Yamagishi Satoru、Yamasaki Tomohiro、Sameshima Tetsuro、Suzuki Tetsuro、Sugimura Haruhiko、Namba Hiroki、Kurozumi Kazuhiko
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 26 Pages: 253-265
- DOI
  10.1016/j.omtm.2022.07.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09325, KAKENHI-PROJECT-20K21499, KAKENHI-PROJECT-23K21369, KAKENHI-PROJECT-17K10861
[Journal Article] Anaplastic changes of diffuse leptomeningeal glioneuronal tumor with polar spongioblastoma pattern2018
- Author(s)
  Yamasaki Tomohiro、Sakai Naoto、Shinmura Kazuya、Kawaji Hiroshi、Koizumi Shinichiro、Samashima Tetsuro、Namba Hiroki
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 35 Issue: 4 Pages: 209-216
- DOI
  10.1007/s10014-018-0326-z
- Data Source
  KAKENHI-PROJECT-17K10861
[Journal Article] Genetically Engineered Multilineage-Differentiating Stress-Enduring Cells as Cellular Vehicles against Malignant Gliomas.2017
- Author(s)
  Tomohiro Yamasaki
- Journal Title
  
  Morecular Therapy oncolytics
  
  Volume: 6 Pages: 45-56
- DOI
  10.1016/j.omto.2017.06.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10861, KAKENHI-PROJECT-26293058
[Presentation] The combinational effect of inhibitor for a fatty acid desaturase and a fatty acid transporter on glioma growth2023
- Author(s)
  Tomohiro Yamasaki, Lumin Zhang, Tyrone Dowdy, Adrian Lita, Kurozumi Kazuhiko, Mioara Larion
- Organizer
  2023The Society of Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08539
[Presentation] Stearoyl-CoA desaturase inhibitor induces apoptosis via enhancing lipolysis in IDH mutant glioma2023
- Author(s)
  Tomohiro Yamasaki
- Organizer
  日本脳腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K10861
[Presentation] グリオーマに対する脂肪酸トランスポーター阻害効果2023
- Author(s)
  山崎友裕, 神尾佳宣, Liu Zhitong, 小泉慎一郎, 黒住和彦, Larion Mioara
- Organizer
  2023日本脳神経外科学会
- Data Source
  KAKENHI-PROJECT-23K08539
[Presentation] Stearoyl-CoA desaturase inhibitor suppresses IDH mutant glioma growth2023
- Author(s)
  Tomohiro Yamasaki, Lumin Zhang, Tyrone Dowdy, Adrian Lita, Mioara Larion
- Organizer
  第82回日本癌学会
- Data Source
  KAKENHI-PROJECT-23K08539
[Presentation] Stearoyl-CoA desaturase inhibitor suppresses IDH mutant glioma growth via enhancing lipolysis2022
- Author(s)
  Tomohiro Yamasaki
- Organizer
  The Society of Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10861
[Presentation] アスピリンのマウス脳動脈瘤破裂予防効果2018
- Author(s)
  山崎友裕
- Organizer
  第43回日本脳卒中学術集会
- Data Source
  KAKENHI-PROJECT-17K10824
[Presentation] 悪性グリオーマの遺伝子細胞療法におけるMuse細胞の腫瘍指向性の検討2017
- Author(s)
  山崎友裕
- Organizer
  第16回　日本再生医療学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16H06849
[Presentation] HSVtk発現プラスミド導入幹細胞を用いたグリオーマ標的 enzyme/prodrugシステムの開発2017
- Author(s)
  山崎友裕
- Organizer
  第76回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10861
[Presentation] Targeted enzyme/drug delivery system for glioma using iPSC-derived NSCs by integration-free HSVtk gene transfer method2017
- Author(s)
  山崎友裕
- Organizer
  第75回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10861
[Presentation] iPSC-derived neural stem cells transfected with HSVtk gene using integration-free method as a feasible carrier for targeted delivery of phosphorylated ganciclovir into glioma cells2017
- Author(s)
  Tomohiro Yamasaki
- Organizer
  The 23rd Annual Meeting of Japan Society of Gene and Cell Therapy
- Data Source
  KAKENHI-PROJECT-17K10861
[Presentation] Muse細胞を用いたグリオーマ自殺遺伝子治療2017
- Author(s)
  山崎友裕
- Organizer
  第15回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K10752
[Presentation] Targeted enzyme/drug delivery system for glioma using iPSC-derived NSCs by virus-free HSVtk gene transfer method2017
- Author(s)
  Tomohiro Yamasaki
- Organizer
  The 14th Meeting of the Asian Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10861
[Presentation] integration-free 幹細胞はグリオーマに対するHSVtk遺伝子産物の適した媒体となる2016
- Author(s)
  山崎友裕
- Organizer
  第34回日本脳腫瘍学会学術集会
- Place of Presentation
  甲府富士屋ホテル
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-16H06849
[Presentation] integration-free 幹細胞はグリオーマに対するHSVtk遺伝子産物の適した媒体となる2016
- Author(s)
  山崎友裕
- Organizer
  第34回日本脳腫瘍学会学術集会
- Place of Presentation
  甲府富士屋ホテル
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-16K10752
[Presentation] Genetically engineered multilineage-differentiating stress-enduring (Muse) cells as cellular assassins against gliomas2016
- Author(s)
  山崎友裕
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  PACIFICO Yokohama
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H06849
[Presentation] New treatment strategy for malignant glioma utilizing tumor-tropic capability of Muse cells transduced with HSVtk gene2016
- Author(s)
  山崎友裕
- Organizer
  The 21st ANNUAL MEETING AND EDUCATION DAY OF THE SOCIETY FOR NEURO-ONCOLOGY
- Place of Presentation
  Scottsdale Fairmont Princess Hotel
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06849
[Presentation] MULTILINEAGE-DIFFERENTIATING STRESS-ENDURING (MUSE) CELLS MIGRATE A LONG DISTANCE TO THE GLIOMA IN THE MOUSE BRAIN2016
- Author(s)
  山崎友裕
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  Nippondaira Hotel, Shizuoka, Japan
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06849
[Presentation] New treatment strategy for malignant gliomautilizing tumor-tropic capability of Muse cells transduced with HSVtk gene2016
- Author(s)
  山崎友裕
- Organizer
  The 21st ANNUAL MEETING AND EDUCATION DAY OF THE SOCIETY FOR NEURO-ONCOLOGY
- Place of Presentation
  Scottsdale Fairmont Princess Hotel
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10752

1. 難波宏樹 (60198405)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 小泉慎一郎 (10456577)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. sameshima tetsuro (00295213)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 神尾佳宣 (10829716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 黒住和彦 (20509608)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 大石知也 (50972428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 山岸覚 (40372362)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Hiramatsu Hisaya (70447803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山崎佳寿美 (90794983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 加藤文度 (60204492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 根木宏明 (10750193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IKENO Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 札場博貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMASAKI Tomohiro 山崎 友裕

Yamasaki Tomohiro 山崎 友裕

山崎 友裕 ヤマサキ トモヒロ

Research Projects

Research Products

Co-Researchers

The role of lipid metabolism in the development of intracranial aneurysm formation and rupture.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

中枢神経系リンパ膜構造の実態と関連疾患病態の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New phase of brain tumor therapy: development of gene and cell therapy with SHED

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞小器官脂質解析によるIDH変異神経膠腫の悪性化機序の解明と治療標的分子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment strategy using Multilineage-differentiating stress-enduring (Muse) cells transduced with HSVtk gene monitored by in vivo Positron Emission Tomography imaging in mouse glioma modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自殺遺伝子幹細胞療法による口腔扁平上皮癌新規治療戦略

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dietary Phytoestrogen Reduces Intracranial Aneurysm Formation in Ovariectomized Female Mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HSVｔｋ遺伝子導入Muse細胞の生体モニタリングと安全性の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of suicide gene stem cell therapy by non-viral gene transfer method and application to glioma therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Migration Capacity of Stem Cells from Human Exfoliated Deciduous Teeth Towards Glioma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases2022

Author(s)

Journal Title

DOI

Data Source

YAMASAKI Tomohiro 山崎友裕

Yamasaki Tomohiro 山崎友裕

山崎友裕ヤマサキトモヒロ