MINABE SHIORI 美辺詩織

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Minabe Shiori 美辺詩織

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Researcher Number	40781571
Other IDs	https://orcid.org/0000-0001-7902-925X
Affiliation (Current)	2026: 東北大学, 東北メディカル・メガバンク機構, 講師
Affiliation (based on the past Project Information) *help	2026: 岩手医科大学, いわて東北メディカル・メガバンク機構, 特命助教 2021 – 2023: 岩手医科大学, いわて東北メディカル・メガバンク機構, 特命助教 2020: 日本医科大学, 大学院医学研究科, 学振特別研究員
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Basic Section 45010:Genetics-related / Basic Section 48020:Physiology-related
Keywords	Principal Investigator ゴナドトロピン / 視床下部 / 神経内分泌学 / 世代継承 / 三世代コホート / 東北メディカル・メガバンク / EWAS / ゲノムコホート / DOHaD / エピゲノム … More / 月経異常 / 男性不妊症 / キスペプチン / 神経内分泌 / 生殖 / 肥満 / GnRH / Kisspeptin / 胎児プログラミング / 性成熟 / 思春期早発症 Less

日本人三世代マルチオミックス解析による非遺伝的DNAメチル化継承の検証Principal Investigator
- Principal Investigator
  
  美辺詩織
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Iwate Medical University
３世代7人家族の網羅的DNAメチル化解析によるエピゲノム世代継承の証明Principal Investigator
- Principal Investigator
  
  美辺詩織
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Iwate Medical University
Neuroendocrine mechanism of precocious puberty caused by fetal stress in uteroPrincipal Investigator
- Principal Investigator
  
  Minabe Shiori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Iwate Medical University
  Nippon Medical School
肥満を基盤とした生殖機能低下を惹起する神経内分泌メカニズムと脳内神経炎症の相関Principal Investigator
- Principal Investigator
  
  美辺詩織
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Iwate Medical University
  Nippon Medical School

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] 東北メディカル・メガバンク（TMM）計画におけるDNAメチル化解析によるDOHaD研究に向けた取り組み2024
- Author(s)
  美辺詩織、小巻翔平、大桃秀樹、清水厚志
- Journal Title
  
  DOHaD研究
  
  Volume: 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14437
[Journal Article] Deterioration of mitochondrial biogenesis and degradation in the endometrium is a cause of subfertility in cows2023
- Author(s)
  Matsuyama Shuichi、Nakamura Sho、Minabe Shiori、Sakatani Miki、Takenouchi Naoki、Sasaki Takuya、Inoue Yuki、Iwata Hisataka、Kimura Koji
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 90 Issue: 3 Pages: 141-152
- DOI
  10.1002/mrd.23670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15650, KAKENHI-PROJECT-20K16123
[Journal Article] Central injection of neuropeptide B induces luteinizing hormone release in male and female rats2023
- Author(s)
  Watanabe Youki、Iwata Kinuyo、Minabe Shiori、Nakao Nobuhiro、Ishii Hirotaka、Ozawa Hitoshi
- Journal Title
  
  Peptides
  
  Volume: 168 Pages: 171064-171064
- DOI
  10.1016/j.peptides.2023.171064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05961, KAKENHI-PROJECT-23K06350, KAKENHI-PROJECT-22K14986, KAKENHI-PROJECT-23K14437
[Journal Article] 生殖制御神経内分泌制御機構への胎児プログラミングの影響2023
- Author(s)
  美辺詩織、小澤一史
- Journal Title
  
  月刊臨床神経科学(Clinical Neuroscience)
  
  Volume: 41 Pages: 1398-1399
- Data Source
  KAKENHI-PROJECT-23K14437
[Journal Article] Long-term effects of prenatal undernutrition on female rat hypothalamic KNDy neurons2023
- Author(s)
  Minabe Shiori、Iwata Kinuyo、Watanabe Youki、Ishii Hirotaka、Ozawa Hitoshi
- Journal Title
  
  Endocrine Connections
  
  Volume: 12 Issue: 1
- DOI
  10.1530/ec-22-0307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14986, KAKENHI-PROJECT-19K15966, KAKENHI-PROJECT-20K16123
[Journal Article] Effect of a neurokinin 3 receptor-selective agonist administration on the embryos recovered from superovulated cows2023
- Author(s)
  Matsuyama Shuichi、Nakamura Sho、Minabe Shiori、Ohkura Satoshi、Kimura Koji
- Journal Title
  
  Biology of Reproduction
  
  Volume: 108 Issue: 6 Pages: 936-944
- DOI
  10.1093/biolre/ioad039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14437
[Journal Article] Single neonatal estrogen implant sterilizes female animals by decreasing hypothalamic KISS1 expression2023
- Author(s)
  Park Chan Jin、Minabe Shiori、Hess Rex A.、Lin Po-Ching Patrick、Zhou Sherry、Bashir Shah Tauseef、Barakat Radwa、Gal Arnon、Ko CheMyong Jay
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-36727-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14437
[Journal Article] Evaluation of short-term epigenetic age fluctuation2022
- Author(s)
  Komaki Shohei、Ohmomo Hideki、Hachiya Tsuyoshi、Sutoh Yoichi、Ono Kanako、Furukawa Ryohei、Umekage So、Otsuka-Yamasaki Yayoi、Minabe Shiori、Takashima Akira、Tanno Kozo、Sasaki Makoto、Shimizu Atsushi
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 14 Issue: 1 Pages: 76-76
- DOI
  10.1186/s13148-022-01293-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16123
[Journal Article] <i>Kiss1</i>-dependent and independent release of luteinizing hormone and testosterone in perinatal male rats2022
- Author(s)
  Chen Jing、Minabe Shiori、Munetomo Arisa、Magata Fumie、Sato Marimo、Nakamura Sho、Hirabayashi Masumi、Ishihara Yasuhiro、Yamazaki Takeshi、Uenoyama Yoshihisa、Tsukamura Hiroko、Matsuda Fuko
- Journal Title
  
  Endocr J
  
  Volume: 69 Issue: 7 Pages: 797-807
- DOI
  10.1507/endocrj.EJ21-0620
- NAID
  130008157963
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15646, KAKENHI-PROJECT-19K21166, KAKENHI-PROJECT-20J40270, KAKENHI-PROJECT-20K12182, KAKENHI-PROJECT-21K19186, KAKENHI-PROJECT-20K16123, KAKENHI-PROJECT-22KJ0504, KAKENHI-PROJECT-20K15650, KAKENHI-PROJECT-21H05031, KAKENHI-PROJECT-23K21260, KAKENHI-PROJECT-23K23759
[Journal Article] Testosterone regulation on quiescin sulfhydryl oxidase 2 synthesis in the epididymis2021
- Author(s)
  Wang Tse-En、Minabe Shiori、Matsuda Fuko、Li Sheng-Hsiang、Tsukamura Hiroko、Maeda Kei-Ichiro、Smith Lee、O’Hara Laura、Gadella Bart M、Tsai Pei-Shiue
- Journal Title
  
  Reproduction
  
  Volume: 161 Issue: 5 Pages: 593-602
- DOI
  10.1530/rep-20-0629
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06206, KAKENHI-PROJECT-18H03973, KAKENHI-PROJECT-20J40270, KAKENHI-PROJECT-20K16123, KAKENHI-PROJECT-21H05031, KAKENHI-PROJECT-23K21260
[Journal Article] Gene-expression profile and postpartum transition of bovine endometrial side population cells†2021
- Author(s)
  Tatebayashi Ryoki、Nakamura Sho、Minabe Shiori、Furusawa Tadashi、Abe Ryoya、Kajisa Miki、Morita Yasuhiro、Ohkura Satoshi、Kimura Koji、Matsuyama Shuichi
- Journal Title
  
  Biology of Reproduction
  
  Volume: 104 Issue: 4 Pages: 850-860
- DOI
  10.1093/biolre/ioab004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15650, KAKENHI-PROJECT-20J40270, KAKENHI-PROJECT-20K16123
[Journal Article] Morphological Analysis of the Hindbrain Glucose Sensor-Hypothalamic Neural Pathway Activated by Hindbrain Glucoprivation2021
- Author(s)
  Sato Marimo、Minabe Shiori、Sakono Takahiro、Magata Fumie、Nakamura Sho、Watanabe Youki、Inoue Naoko、Uenoyama Yoshihisa、Tsukamura Hiroko、Matsuda Fuko
- Journal Title
  
  Endocrinology
  
  Volume: 162 Issue: 9 Pages: 1-18
- DOI
  10.1210/endocr/bqab125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15646, KAKENHI-PROJECT-19K21166, KAKENHI-PROJECT-19H03103, KAKENHI-PROJECT-20J40270, KAKENHI-PROJECT-21K19186, KAKENHI-PROJECT-19K15966, KAKENHI-PROJECT-20K15650, KAKENHI-PROJECT-20K16123, KAKENHI-PROJECT-21H05031, KAKENHI-PROJECT-23K21260
[Journal Article] Effect of diet-induced obesty Kiss1/Tac3/Pdyn gene expression in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male and female rats.2021
- Author(s)
  10.10.16/j.peptides.2021.170546
- Journal Title
  
  Peptides
  
  Volume: in press Pages: 170546-170546
- DOI
  10.1016/j.peptides.2021.170546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06860, KAKENHI-PROJECT-18H03973, KAKENHI-PROJECT-20J40270, KAKENHI-PROJECT-20K16123, KAKENHI-PROJECT-21K19186, KAKENHI-PROJECT-21H05031
[Journal Article] Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice2020
- Author(s)
  Shiori Minabe, Sho Nakamura, Eri Fukushima, Marimo Sato, Kana Ikegami, Teppei Goto, Makoto Sanbo, Masumi Hirabayashi, Junko Tomikawa, Takuya Imamura, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura, Kei-Ichiro Maeda, Fuko Matsuda
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: Epub Issue: 4 Pages: 369-375
- DOI
  10.1262/jrd.2019-164
- NAID
  130007888724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22368, KAKENHI-PROJECT-19K16270, KAKENHI-PROJECT-19H03138, KAKENHI-PROJECT-17K07248, KAKENHI-PROJECT-18K19267, KAKENHI-PROJECT-20K06605, KAKENHI-PROJECT-20K15650, KAKENHI-PROJECT-16H06206, KAKENHI-PROJECT-18H03973, KAKENHI-PROJECT-20J40270, KAKENHI-PROJECT-20K16123, KAKENHI-PROJECT-19H03103
[Presentation] 新生児臍帯血の網羅的エピゲノム解析による妊娠初期までの喫煙経験が次世代に及ぼす影響2023
- Author(s)
  美辺詩織、小巻翔平、高嶋聰、小野加奈子、山_弥生、須藤洋一、大桃秀樹、小原拓、熊田和貴、石黒真美、工藤久智、田高周、水野聖士、木下賢吾、勝岡史城、荻島創一、菅原準一、栗山進一、清水厚志
- Organizer
  第11回日本DOHaD学会学術集会
- Data Source
  KAKENHI-PROJECT-23K14437
[Presentation] 三世代出生コホートにおける7人家族のエピゲノム研究基盤構築2023
- Author(s)
  美辺詩織、小巻翔平、高嶋聰、小野加奈子、山_弥生、須藤洋一、大桃秀樹、小原拓、熊田和貴、石黒真美、工藤久智、田高周、水野聖士、木下賢吾、勝岡史城、荻島創一、菅原準一、栗山進一、清水厚志
- Organizer
  第23回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-23K14437
[Presentation] 発達期の栄養環境が生殖神経内分泌機構に及ぼす影響2023
- Author(s)
  美辺詩織、岩田衣世、渡辺雄貴、石井寛高、小澤一史
- Organizer
  第49回日本神経内分泌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14437
[Presentation] 発達期環境ストレスによる生殖機能不全をもたらす神経内分泌メカニズム2022
- Author(s)
  美辺詩織、岩田衣世、渡辺雄貴、石井寛高、井上直子、上野山賀久、束村博子、小澤一史
- Organizer
  日本内分泌学会第 40 回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K16123
[Presentation] 発達期エストロゲン曝露による生殖機能不全をもたらす神経内分泌メカニズム2022
- Author(s)
  美辺詩織、井上直子、上野山賀久、小澤一史、束村博子
- Organizer
  第94回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16123
[Presentation] 発達期環境ストレスと神経内分泌メカニズム2022
- Author(s)
  美辺詩織、井上直子、上野山賀久、小澤一史、束村博子
- Organizer
  第22回日本内分泌学会関東甲信越支部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16123
[Presentation] 発達期エストロゲン曝露による生殖機能不全をもたらす神経内分泌メカニズム2022
- Author(s)
  美辺詩織、井上直子、上野山賀久、小澤一史、束村博子
- Organizer
  第94回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20J40270
[Presentation] 発達期環境ストレスと神経内分泌メカニズム2022
- Author(s)
  美辺詩織、井上直子、上野山賀久、小澤一史、束村博子
- Organizer
  第22回日本内分泌学会関東甲信越支部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20J40270
[Presentation] Effects of Diet-Induced Obesity on Hypothalamic Kisspeptin-Neurokinin B-Dynorphin (KNDy) Neurons and Luteinizing Hormone Secretion in Sex Hormone-Primed Male and Female Rats2021
- Author(s)
  Minabe, S., Iwata, K. and Ozawa, H.
- Organizer
  ENDO2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16123
[Presentation] Neonatal exposure to estrogen causes irreversible infertility via specific suppressive action on hypothalamic Kiss1 neurons in male and female rodents2021
- Author(s)
  美辺詩織、井上直子、上野山賀久、小澤一史、束村博子
- Organizer
  第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16123
[Presentation] Neonatal exposure to estrogen causes irreversible infertility via specific suppressive action on hypothalamic Kiss1 neurons in male and female rodents2021
- Author(s)
  美辺詩織、井上直子、上野山賀久、小澤一史、束村博子
- Organizer
  第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20J40270
[Presentation] Effects of Diet-Induced Obesity on Hypothalamic Kisspeptin-Neurokinin B-Dynorphin (KNDy) Neurons and Luteinizing Hormone Secretion in Sex Hormone-Primed Male and Female Rats2021
- Author(s)
  Minabe, S., Iwata, K. and Ozawa, H.
- Organizer
  ENDO2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20J40270

1. MATSUDA Fuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. NAKAO Nobuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 中村翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 渡辺雄貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 真方文絵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 今村拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MINABE SHIORI 美辺 詩織

Minabe Shiori 美辺 詩織

Research Projects

Research Products

Co-Researchers

日本人三世代マルチオミックス解析による非遺伝的DNAメチル化継承の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

３世代7人家族の網羅的DNAメチル化解析によるエピゲノム世代継承の証明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neuroendocrine mechanism of precocious puberty caused by fetal stress in uteroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肥満を基盤とした生殖機能低下を惹起する神経内分泌メカニズムと脳内神経炎症の相関Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 東北メディカル・メガバンク（TMM）計画におけるDNAメチル化解析によるDOHaD研究に向けた取り組み2024

Author(s)

Journal Title

Data Source

[Journal Article] Deterioration of mitochondrial biogenesis and degradation in the endometrium is a cause of subfertility in cows2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Central injection of neuropeptide B induces luteinizing hormone release in male and female rats2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 生殖制御神経内分泌制御機構への胎児プログラミングの影響2023

Author(s)

Journal Title

Data Source

[Journal Article] Long-term effects of prenatal undernutrition on female rat hypothalamic KNDy neurons2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of a neurokinin 3 receptor-selective agonist administration on the embryos recovered from superovulated cows2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single neonatal estrogen implant sterilizes female animals by decreasing hypothalamic KISS1 expression2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of short-term epigenetic age fluctuation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>Kiss1</i>-dependent and independent release of luteinizing hormone and testosterone in perinatal male rats2022

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Testosterone regulation on quiescin sulfhydryl oxidase 2 synthesis in the epididymis2021

Author(s)

Journal Title

DOI

Data Source

MINABE SHIORI 美辺詩織

Minabe Shiori 美辺詩織