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Kubo Fumi  久保 郁

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KUBO Fumi  久保 郁

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Researcher Number 40786373
Other IDs
Affiliation (Current) 2026: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help 2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームディレクター
2022 – 2024: 国立遺伝学研究所, 遺伝形質研究系, 准教授
2022 – 2023: 国立遺伝学研究所, 大学共同利用機関等の部局等, 特命准教授
2020 – 2022: 国立遺伝学研究所, 新分野創造センター, 准教授
Review Section/Research Field
Principal Investigator
Basic Section 46010:Neuroscience-general-related / Biological Sciences
Except Principal Investigator
Medium-sized Section 38:Agricultural chemistry and related fields / Biological Sciences
Keywords
Principal Investigator
ゼブラフィッシュ / 前視蓋 / 視覚 / オプティックフロー / 神経回路 / 方位選択性 / 社会行動 / 視覚行動 / 神経回路ネットワーク / DMD … More / ANTs / ハブ / 光遺伝学 / 視覚情報処理 / 神経ネットワーク / FuGIMA / カルシウムイメージング / 電子顕微鏡画像解析 / コネクトーム / Ca^<2+>イメージング / 視覚情報 … More
Except Principal Investigator
ユビキチン / プロテインノックダウン / 発現制御 / デグロン / タンパク質分解 / 発現調節 / 神経回路 / シナプス可塑性 / 記憶 Less
  • Research Projects

    (5 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (14 People)
  •  視覚による社会性行動制御の神経基盤Principal Investigator

    • Principal Investigator
      久保 郁
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  記憶メカニズムの多次元解析 - nmからメゾスケール/ミリ秒から日スケールまで

    • Principal Investigator
      林 康紀
    • Project Period (FY)
      2022 – 2028
    • Research Category
      Fund for the Promotion of Joint International Research (International Leading Research )
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Visual processing hub that triggers wide-spread network activityPrincipal Investigator

    • Principal Investigator
      Kubo Fumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      National Institute of Genetics
  •  Development of advanced foundational technology for the AID2 method enabling rapid protein degradation in cells and animals.

    • Principal Investigator
      Kanemaki Masato
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      National Institute of Genetics
  •  Investigation of mechanisms underlying visual processing and behaviorPrincipal Investigator

    • Principal Investigator
      KUBO Fumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics

All 2025 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Multiphasic protein condensation governed by shape and valency2025

    • Author(s)
      Pandey Vikas、Hosokawa Tomohisa、Hayashi Yasunori、Urakubo Hidetoshi
    • Journal Title

      Cell Reports

      Volume: 44 Issue: 4 Pages: 115504-115504

    • DOI

      10.1016/j.celrep.2025.115504

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H04981, KAKENHI-PROJECT-20K12062, KAKENHI-PROJECT-22K21353
  • [Journal Article] Live imaging of center of calcification formation during septum development in primary polyps of Acropora digitifera2024

    • Author(s)
      Ohno Yoshikazu、Takahashi Anan、Tsutsumi Motosuke、Kubota Azusa、Iguchi Akira、Iijima Mariko、Mizusawa Nanami、Nakamura Takashi、Suzuki Atsushi、Suzuki Michio、Yasumoto Jun、Watabe Shugo、Sakai Kazuhiko、Nemoto Tomomi、Yasumoto Ko
    • Journal Title

      Frontiers in Marine Science

      Volume: 11 Pages: 1-13

    • DOI

      10.3389/fmars.2024.1406446

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05771, KAKENHI-PROJECT-23H00339, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-22K21353
  • [Journal Article] Establishment and characterization of mouse lines useful for endogenous protein degradation via an improved auxin‐inducible degron system (AID2)2024

    • Author(s)
      Makino‐Itou Hatsune、Yamatani Noriko、Okubo Akemi、Kiso Makoto、Ajima Rieko、Kanemaki Masato T.、Saga Yumiko
    • Journal Title

      Development, Growth and Differentiation

      Volume: 66 Issue: 7 Pages: 384-393

    • DOI

      10.1111/dgd.12942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04719
  • [Journal Article] Spontaneous activity in whisker-innervating region of neonatal mouse trigeminal ganglion2022

    • Author(s)
      Banerjee Piu、Kubo Fumi、Nakaoka Hirofumi、Ajima Rieko、Sato Takuya、Hirata Tatsumi、Iwasato Takuji
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 16311-16311

    • DOI

      10.1038/s41598-022-20068-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18245, KAKENHI-PROJECT-20H03346, KAKENHI-PROJECT-21K19281, KAKENHI-PROJECT-20H03345, KAKENHI-PROJECT-21H02586
  • [Journal Article] RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells2022

    • Author(s)
      Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.
    • Journal Title

      Commun Biol

      Volume: 5 Issue: 1 Pages: 1420-1420

    • DOI

      10.1038/s42003-022-04369-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22H00457, KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-22KJ3105, KAKENHI-PROJECT-21K19419, KAKENHI-PROJECT-20K16344, KAKENHI-PROJECT-19H03156, KAKENHI-PLANNED-18H05532, KAKENHI-PLANNED-17H06426, KAKENHI-PUBLICLY-22H05599, KAKENHI-PROJECT-23K23810, KAKENHI-PROJECT-20H00524, KAKENHI-PROJECT-21H04719
  • [Journal Article] 脳全体のイメージングからわかること2022

    • Author(s)
      久保郁
    • Journal Title

      生体の科学 連載講座 ヒトを知るモデル動物としてのゼブラフィッシュ-3

      Volume: 73 Pages: 81-85

    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Journal Article] Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain2022

    • Author(s)
      Fabian Svara, Dominique Foerster, Fumi Kubo, Michal Januszewski, Marco dal Maschio, Philipp J. Schubert, Joergen Kornfeld, Adrian A. Wanner, Eva Laurell, Winfried Denk, Herwig Baier
    • Journal Title

      Nature Methods

      Volume: 19 Issue: 11 Pages: 1357-1366

    • DOI

      10.1038/s41592-022-01621-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Journal Article] Circuit Organization Underlying Optic Flow Processing in Zebrafish2021

    • Author(s)
      Matsuda K and Kubo F
    • Journal Title

      Front. Neural Circuits

      Volume: 15 Pages: 709048-709048

    • DOI

      10.3389/fncir.2021.709048

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02586, KAKENHI-PROJECT-20K15906
  • [Journal Article] 特集 「目」の神経学 錯視を生じる脳のしくみ-ゼブラフィッシュの運動残効から2021

    • Author(s)
      久保郁
    • Journal Title

      BRAIN and NERVE

      Volume: 73 Issue: 11 Pages: 1237-1241

    • DOI

      10.11477/mf.1416201923

    • ISSN
      1344-8129, 1881-6096
    • Year and Date
      2021-11-01
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Journal Article] An Optical Illusion Pinpoints an Essential Circuit Node for Global Motion Processing2020

    • Author(s)
      Yunmin Wu, Marco dal Maschio, Fumi Kubo, Herwig Baier
    • Journal Title

      Neuron

      Volume: 108 Issue: 4 Pages: 722-734

    • DOI

      10.1016/j.neuron.2020.08.027

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Journal Article] A calibrated optogenetic toolbox of stable zebrafish opsin lines2020

    • Author(s)
      Antinucci P, Dumitrescu A, Deleuze C, Morley HJ, Leung K, Hagley T, Kubo F, Baier H, Bianco IH, Wyart C.
    • Journal Title

      eLife

      Volume: 9

    • DOI

      10.7554/elife.54937

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Journal Article] A Cellular-Resolution Atlas of the Larval Zebrafish Brain2019

    • Author(s)
      Kunst M, Laurell E, Mokayes N, Kramer A, Kubo F, Fernandes AM, Förster D, Dal Maschio M, Baier H.
    • Journal Title

      Neuron

      Volume: 103 Issue: 1 Pages: 21-38

    • DOI

      10.1016/j.neuron.2019.04.034

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Journal Article] 視覚による行動選択の神経基盤2019

    • Author(s)
      久保 郁
    • Journal Title

      生体の科学 特集「脳神経回路のダイナミクスから探る脳の発達・疾患・老化」

      Volume: 70 Pages: 53-57

    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Journal Article] Neuronal Architecture of a Visual Center that Processes Optic Flow2019

    • Author(s)
      Kramer A, Wu Y, Baier H, Kubo F.
    • Journal Title

      Neuron

      Volume: 103 Issue: 1 Pages: 118-132

    • DOI

      10.1016/j.neuron.2019.04.018

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Journal Article] Optogenetic precision toolkit to reveal form, function and connectivity of single neurons2018

    • Author(s)
      Förster D, Kramer A, Baier H, Kubo F.
    • Journal Title

      Methods

      Volume: 50 Pages: 42-48

    • DOI

      10.1016/j.ymeth.2018.08.012

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Molecular targeting and functional analysis of neuronal subtypes of the optic flow processing circuit in larval zebrafish2024

    • Author(s)
      久保 郁
    • Organizer
      Neuro2024シンポジウム
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] 視覚の情報処理と行動を支える神経回路2024

    • Author(s)
      久保 郁
    • Organizer
      京都大学生命科学研究科創立25周年記念シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] ゼブラフィッシュにおける神経ネットワーク解析:大規模神経活動イメージングとそれに直交するアプローチ2024

    • Author(s)
      久保 郁
    • Organizer
      生理研研究会「大規模脳活動計測 我々は何を測り、どこへ行くのか?」
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] Neural network analysis using activity-based cell labeling and transcriptome analysis in zebrafish2024

    • Author(s)
      久保 郁
    • Organizer
      第97回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] 小型脊椎動物モデルを用いた視覚研究2024

    • Author(s)
      久保 郁
    • Organizer
      Neuro2024教育講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] 神経活動依存的な細胞標識とトランスクリプトーム解析を用いた神経ネットワーク解析2023

    • Author(s)
      久保 郁
    • Organizer
      第46回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] 神経活動依存的な細胞標識とトランスクリプトーム解析を用いた神経ネットワーク解析2023

    • Author(s)
      久保 郁
    • Organizer
      第46回日本分子生物学会 2023年12月 口頭発表、招待有り
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] Intersectional genetics for investigating putative pretectal hub neurons in the optic flow processing circuit2023

    • Author(s)
      Chung-Han Wang, Fumi Kubo.
    • Organizer
      Cold Spring Harbor Laboratory Meeting, Zebrafish Neurobiology 2023 Nov. Poster
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] Genetically targeted pretectal neurons constitute inhibitory circuits for optic flow processing2023

    • Author(s)
      Koji Matsuda, Carolina Fiallos Oliveros, Tomoya Shiraki, Koichi Kawakami, Fumi Kubo
    • Organizer
      Cold Spring Harbor Laboratory Meeting, Zebrafish Neurobiology 2023 Nov. Poster
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] 動きの視覚情報処理を担う神経回路2023

    • Author(s)
      久保 郁
    • Organizer
      第5回 三融会・武田神経科学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] Genetically targeted pretectal neurons constitute inhibitory circuits for optic flow processing2023

    • Author(s)
      久保 郁
    • Organizer
      Cold Spring Harbor Laboraotory meeting Zebrafish Neurobiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] Functional and morphological characterization of zebrafish retinal ganglion cell subtypes expressing the transcription factor Satb22023

    • Author(s)
      Ayjan Urazbayeva, Fumi Kubo.
    • Organizer
      Cold Spring Harbor Laboratory Meeting, Zebrafish Neurobiology 2023 Nov. Poster
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K21353
  • [Presentation] 錯視反応を用いた動きの視覚情報処理と予測を担う神経回路の解析2022

    • Author(s)
      久保 郁
    • Organizer
      Neuro2022
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] ゼブラフィッシュ脳のイメージングから探る視覚機能2022

    • Author(s)
      久保 郁
    • Organizer
      Neuro2022 ソーラボジャパン株式会社 ランチョンセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] 動きの視覚情報処理を担う神経回路:錯視反応を用いた解析から2022

    • Author(s)
      久保 郁
    • Organizer
      日本視覚学会 2022年度 夏季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] ゼブラフィッシュにおけるオプティックフロー情報処理の神経回路基盤2022

    • Author(s)
      久保 郁
    • Organizer
      視覚科学フォーラム・生理研研究会「機能と構造の視覚科学研究会」
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] 動きの視覚情報処理を担う神経回路:錯視反応を用いた解析から2022

    • Author(s)
      久保 郁
    • Organizer
      第45回日本分子生物学会 ワークショップ「多様なモデル生物を用いた発生・行動・進化神経科学の最前線」
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] ゼブラフィッシュ前視蓋におけるオプティックフロー情報処理回路の機能と神経接続2021

    • Author(s)
      久保 郁
    • Organizer
      第43回日本神経科学大会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] Cracking the visual motion processing circuit using optical illusion2021

    • Author(s)
      久保 郁
    • Organizer
      遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム2021」
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02586
  • [Presentation] ゼブラフィッシュにおける錯視反応とその視覚情報処理回路2020

    • Author(s)
      久保 郁
    • Organizer
      第18回 北海道大学脳科学研究教育センターシンポジウム 「感覚と運動の神経基盤の進化 ~非哺乳類脳から学ぶ計算原理~」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] 錯視反応を用いた動きの視覚情報処理を担う神経回路の解析2020

    • Author(s)
      久保 郁
    • Organizer
      第43回 日本神経科学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] ゼブラフィッシュにおける視覚情報処理と行動制御メカニズム2019

    • Author(s)
      久保 郁
    • Organizer
      感覚器研究イニシアチブ・シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Function and connectivity of a visual circuit underlying optic flow processing in zebrafish2019

    • Author(s)
      久保 郁
    • Organizer
      The Joint Symposium on Fusion of Biomedical and Physical/Informational Sciences in Neurobiology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] オプティックフロー情報処理に関わる神経回路の解剖学的基盤2019

    • Author(s)
      久保 郁
    • Organizer
      Neuro2019、シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Neuronal architecture of a visual center that processes optic flow2019

    • Author(s)
      久保 郁
    • Organizer
      第42回日本分子生物学会年会、ワークショップ
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] 視運動の情報処理に関わる神経ネットワークのイメージング解析2019

    • Author(s)
      久保 郁
    • Organizer
      第13回バイオイメージングフォーラム&基生研重点共同利用合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] 全脳にわたる包括的な神経ネットワーク解析とその先2019

    • Author(s)
      久保 郁
    • Organizer
      Neuro2019、大会長企画シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Cellular composition of the optic flow processing circuit in the zebrafish pretectum2018

    • Author(s)
      久保 郁
    • Organizer
      国立遺伝学研究所・研究会「哺乳類脳の機能的神経回路の構築メカニズム」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Function and connectivity of optic flow processing circuit in the zebrafish pretectum2018

    • Author(s)
      久保 郁
    • Organizer
      第41回神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Function and connectivity of optic flow processing circuit in the zebrafish pretectum2018

    • Author(s)
      久保 郁
    • Organizer
      第24回小型魚類研究会
    • Data Source
      KAKENHI-PROJECT-17K20147
  • [Presentation] Function and connectivity of optic flow processing circuit in the zebrafish pretectum2018

    • Author(s)
      久保 郁
    • Organizer
      Cold Spring Harbor Asia Conference “Latest Advances in Development & Function of Neuronal Circuits”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20147
  • 1.  Kanemaki Masato (20444507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  林 康紀 (90466037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  池谷 裕二 (10302613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  柚崎 通介 (40365226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  根本 知己 (50291084)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  米原 圭祐 (80510619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  三國 貴康 (90786477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  林 謙一郎 (30289136)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  西野 達哉 (50533155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KITAGAWA Mako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  FIALLOS OLIVEROS Carolina
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKUBO Keiyo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  岩里 琢治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  鈴木 道生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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