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Otake Shigeo  大嶽 茂雄

ORCIDConnect your ORCID iD *help
Researcher Number 40796984
Other IDs
Affiliation (based on the past Project Information) *help 2019 – 2022: 山梨大学, 大学院総合研究部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49010:Pathological biochemistry-related
Keywords
Principal Investigator
転写因子 / 癌 / EMT / E-cadherin / ZEB1 / CtBP / HDAC / TGF-β / がん悪性化 / PKC / Ras
  • Research Projects

    (2 results)
  • Research Products

    (3 results)
  •  Study on the functional regulation of ZEB1 by TGF-beta signalingPrincipal Investigator

    • Principal Investigator
      Otake Shigeo
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      University of Yamanashi
  •  Study on the functional regulation of the tumor-promoting transcription factor ZEB1Principal Investigator

    • Principal Investigator
      Otake Shigeo
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      University of Yamanashi

All 2022 2020

All Journal Article Presentation

  • [Journal Article] ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus‐dependent E‐cadherin downregulation2020

    • Author(s)
      Otake Shigeo、Itoh Yuka、Omata Chiho、Saitoh Masao、Miyazawa Keiji
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 1 Pages: 205-216

    • DOI

      10.1111/cas.14701

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16537
  • [Presentation] TGF-β downregulates CDH1 expression via the CtBP-independent ZEB1 pathway2022

    • Author(s)
      Shigeo Otake, Masao Saitoh, Keiji Miyazawa
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K15371
  • [Presentation] Novel mechanism of E-cadherin downregulation by ZEB1 and oncogenic Ras2020

    • Author(s)
      Shigeo Otake, Masao Saitoh, Keiji Miyazawa
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K16537

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