Kurebayashi Yutaka 紅林泰

Researcher Number	40805123
Other IDs	https://orcid.org/0000-0003-3773-0851
Affiliation (Current)	2026: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 慶應義塾大学, 医学部(信濃町), 講師 2021: 慶應義塾大学, 医学部(信濃町), 助教 2017 – 2018: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Human pathology
Keywords	Principal Investigator 腫瘍免疫 / 微小環境 / 肝細胞癌 / 病理 / 好中球 / 大腸癌 / 多様性 / 転移 / 進行がん / 肝臓 … More / 予後予測 / 免疫療法 / 病理学 / 免疫学 / 形質細胞 / B細胞 / 免疫 / 肝 Less

空間的遺伝子発現解析を用いたヒトに特徴的な腫瘍微小環境の全体像の解明Principal Investigator
- Principal Investigator
  
  紅林泰
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Keio University
Histopathological classification of the immune microenvironment of hepatocellular carcinoma including all clinical stagesPrincipal Investigator
- Principal Investigator
  
  Kurebayashi Yutaka
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Keio University
Comprehensive analysis of immune microenvironment in hepatocellular carcinoma (HCC)Principal Investigator
- Principal Investigator
  
  Kurebayashi Yutaka
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Human pathology
- Research Institution
  Keio University

All 2025 2024 2023 2022 2021 2018

All Journal Article Presentation

[Journal Article] Chronological changes in etiology, pathological and imaging findings in primary liver cancer from 2001 to 20202025
- Author(s)
  Tsuzaki Junya、Ueno Akihisa、Masugi Yohei、Tamura Masashi、Yamazaki Seiichiro、Matsuda Kosuke、Kurebayashi Yutaka、et al.
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 55 Issue: 4 Pages: 362-371
- DOI
  10.1093/jjco/hyae187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-21K15390
[Journal Article] An organoid library unveils subtype-specific IGF-1 dependency via a YAP-AP1 axis in human small cell lung cancer2025
- Author(s)
  Fukushima T et al.
- Journal Title
  
  Nature Cancer
  
  Volume: - Issue: 5 Pages: 874-891
- DOI
  10.1038/s43018-025-00945-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08290, KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-24K10434, KAKENHI-PROJECT-24K11360
[Journal Article] Molecular Classification of Hepatocellular Carcinoma based on Zoned Metabolic Feature and Oncogenic Signaling Pathway2025
- Author(s)
  Aoki Tomoko、Nishida Naoshi、Kurebayashi Yutaka、Sakai Kazuko、Fujiwara Naoto、Tsurusaki Masakatsu、Hanaoka Kohei、Morita Masahiro、Chishina Hirokazu、Takita Masahiro、Hagiwara Satoru、Ida Hiroshi、Ueshima Kazuomi、Minami Yasunori、et al.
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: - Issue: 3 Pages: 981-1002
- DOI
  10.3350/cmh.2024.1088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-24K10393
[Journal Article] Macrotrabecular hepatocellular carcinoma: Unique immunovascular characteristics2025
- Author(s)
  Kurebayashi Yutaka、Sakamoto Michiie
- Journal Title
  
  Hepatology
  
  Volume: - Issue: 2 Pages: 203-205
- DOI
  10.1097/hep.0000000000001339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15407
[Journal Article] Spatial Dynamics of T- and B-Cell Responses Predicts Clinical Outcome of Resectable and Unresectable Hepatocellular Carcinoma2024
- Author(s)
  Kurebayashi Yutaka、Sugimoto Katsutoshi、Tsujikawa Hanako、Matsuda Kosuke、Nomura Rui、Ueno Akihisa、Masugi Yohei、Yamazaki Ken、Effendi Kathryn、Takeuchi Hirohito、Itoi Takao、Hasegawa Yasushi、Abe Yuta、Kitago Minoru、Ojima Hidenori、Sakamoto Michiie
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 30 Issue: 24 Pages: 5666-5680
- DOI
  10.1158/1078-0432.ccr-24-0479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15407
[Journal Article] Vessels encapsulating tumor clusters contribute to the intratumor heterogeneity of HCC on Gd-EOB-DTPA?enhanced MRI2024
- Author(s)
  Matsuda Kosuke、Ueno Akihisa、Tsuzaki Junya、Kurebayashi Yutaka、Masugi Yohei、Yamazaki Ken、Tamura Masashi、Abe Yuta、Hasegawa Yasushi、Kitago Minoru、Jinzaki Masahiro、Sakamoto Michiie
- Journal Title
  
  Hepatology Communications
  
  Volume: 9 Issue: 1
- DOI
  10.1097/hc9.0000000000000593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-21K15390
[Journal Article] Comparative Immunohistochemical Analysis of Clinicopathological Subgroups in Hepatocellular Carcinomas from Japan and Indonesia2024
- Author(s)
  Effendi Kathryn、Rahadiani Nur、Stephanie Marini、Kurebayashi Yutaka、Tsujikawa Hanako、Jasirwan Chyntia O.M.、Syaiful Ridho A.、Sakamoto Michiie
- Journal Title
  
  Journal of Clinical and Experimental Hepatology
  
  Volume: 14 Issue: 6 Pages: 101451-101451
- DOI
  10.1016/j.jceh.2024.101451
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15407
[Journal Article] Immunovascular microenvironment in relation to prognostic heterogeneity of WNT/β‐catenin‐activated hepatocellular carcinoma2023
- Author(s)
  Matsuda Kosuke、Kurebayashi Yutaka、Masugi Yohei、Yamazaki Ken、Ueno Akihisa、Tsujikawa Hanako、Ojima Hidenori、Kitago Minoru、Itano Osamu、Shinoda Masahiro、Abe Yuta、Sakamoto Michiie
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 4 Pages: 344-356
- DOI
  10.1111/hepr.13869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-21K15390, KAKENHI-PROJECT-21K15408
[Journal Article] IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis2023
- Author(s)
  Fujimori Sota、Chu Po-Sung、Teratani Toshiaki、Harada Yosuke、Suzuki Takahiro、Amiya Takeru、Taniki Nobuhito、Kasuga Ryosuke、Mikami Yohei、Koda Yuzo、Ichikawa Masataka、Tabuchi Takaya、Morikawa Rei、Yamataka Karin、Noguchi Fumie、Tsujikawa Hanako、Kurebayashi Yutaka、Sakamoto Michiie、Kanai Takanori、Nakamoto Nobuhiro
- Journal Title
  
  JHEP Reports
  
  Volume: - Issue: 7 Pages: 100757-100757
- DOI
  10.1016/j.jhepr.2023.100757
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-21H02906
[Journal Article] Tumor steatosis and glutamine synthetase expression in patients with advanced hepatocellular carcinoma receiving atezolizumab plus bevacizumab therapy2023
- Author(s)
  Kurebayashi Yutaka、Tsujikawa Hanako、Sugimoto Katsutoshi、Yunaiyama Daisuke、Araki Yoichi、Saito Kazuhiro、Takahashi Hiroshi、Kakegawa Tatsuya、Wada Takuya、Tomita Yusuke、Abe Masakazu、Yoshimasu Yu、Takeuchi Hirohito、Hirata Taiki、Sakamaki Kentaro、Kakimi Kazuhiro、Nagao Toshitaka、Itoi Takao、Sakamoto Michiie
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 10 Pages: 1008-1020
- DOI
  10.1111/hepr.13933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15407, KAKENHI-PROJECT-23K06432
[Journal Article] Immunovascular classification of HCC reflects reciprocal interaction between immune and angiogenic tumor microenvironments2021
- Author(s)
  Kurebayashi Yutaka、Matsuda Kosuke、Ueno Akihisa、Tsujikawa Hanako、Yamazaki Ken、Masugi Yohei、Kwa Wit Thun、Effendi Kathryn、Hasegawa Yasushi、Yagi Hiroshi、Abe Yuta、Kitago Minoru、Ojima Hidenori、Sakamoto Michiie
- Journal Title
  
  Hepatology
  
  Volume: 75 Issue: 5 Pages: 1139-1153
- DOI
  10.1002/hep.32201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15390, KAKENHI-PROJECT-21K15407
[Journal Article] Landscape of immune microenvironment in hepatocellular carcinoma and its additional impact on histological and molecular classification.2018
- Author(s)
  Yutaka Kurebayashi, Hidenori Ojima, Hanako Tsujikawa, Naoto Kubota, Junki Maehara, Yuta Abe, Minoru Kitago, Masahiro Shinoda, Yuko Kitagawa, and Michiie Sakamoto
- Journal Title
  
  HEPATOLOGY
  
  Volume: 印刷中 Issue: 3 Pages: 1025-1041
- DOI
  10.1002/hep.29904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H07089
[Presentation] 肝細胞癌における抗腫瘍免疫応答の形質・空間的全体像と複合免疫療法の治療効果との関係2024
- Author(s)
  紅林　泰
- Organizer
  第60回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌の腫瘍微小環境と免疫療法の治療効果の関係について2024
- Author(s)
  紅林　泰
- Organizer
  第44回日本画像医学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌における病理学・腫瘍免疫学の統合的理解と複合免疫療法の治療効果予測への応用2024
- Author(s)
  紅林　泰
- Organizer
  第50回日本急性肝不全研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌における抗腫瘍免疫応答の形質・空間的全体像の解明2024
- Author(s)
  紅林泰, 松田紘典, 辻川華子, 上野彰久, kathryn Effendi, 山崎剣, 眞杉洋平, 尾島英知, 坂元亨宇
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌の免疫微小環境の解明と治療効果予測への応用ならびにWnt/β-catenin経路の関与について2024
- Author(s)
  紅林　泰
- Organizer
  第10回久留米消化器Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌における抗腫瘍免疫応答の形質・空間的全体像の解明2024
- Author(s)
  紅林　泰
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] Classification of Immune and Immunovascular Tumor Microenvironment of Hepatocellular Carcinoma through Detailed Histopathological Analysis2023
- Author(s)
  紅林　泰
- Organizer
  14th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌に対する抗腫瘍免疫応答の発達・疲弊過程の時空間的解析と臨床病理学的意義2023
- Author(s)
  紅林泰, 松田紘典, 辻川華子, 上野彰久, kathryn Effendi, 山崎剣, 眞杉洋平, 尾島英知, 坂元亨宇
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 腫瘍内脂肪化とグルタミン合成酵素発現は進行肝細胞癌に対する複合免疫療法の治療効果予測因子である2023
- Author(s)
  紅林　泰
- Organizer
  第59回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌における免疫微小環境の発達・疲弊過程の時空間的解析と原発巣・転移巣間多様性2023
- Author(s)
  紅林　泰
- Organizer
  第59回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌最適医療に向けた腫瘍免疫・血管微小環境に基づく分類（Immuno-vascular Subtype）ワークショップ9 肝疾患における免疫病態の解明と治療応用2022
- Author(s)
  紅林　泰
- Organizer
  第30回日本消化器関連学会週間（JDDW）
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌の免疫・血管微小環境に基づく分類：免疫チェックポイント阻害剤併用療法の効果予測を見据えて（一般口演 15 肝胆膵2）2022
- Author(s)
  紅林　泰
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌の病理学と腫瘍免疫学の統合的理解に向けて2022
- Author(s)
  紅林　泰
- Organizer
  第64回肝癌症例検討会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 特別企画9 キャリア支援・ダイバーシティ推進委員会第２部：論文アクセプト体験記～トップジャーナルに挑む～2022
- Author(s)
  紅林　泰
- Organizer
  第58回日本肝臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌の免疫微小環境と免疫学的サブタイプ分類：ワークショップ3 臨床免疫領域における画像・組織による診断・病型分類の役割2022
- Author(s)
  紅林　泰
- Organizer
  第50回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌腫瘍免疫・血管微小環境の病理学的分類：肝癌免疫併用療法の治療効果予測と層別化に向けて（パネルディスカッション5 肝癌免疫療法の治療成績向上を目指して）2022
- Author(s)
  紅林　泰
- Organizer
  第58回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] Hepatocellular Carcinoma Tumor Microenvironment (LCSGJ-KLCA Joint Symposium: Updates on Molecular Signatures of Hepatocellular Carcinoma)2021
- Author(s)
  Yutaka Kurebayashi
- Organizer
  The Liver Week 2021 (Seoul, South Korea)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 免疫チェックポイント阻害剤併用療法の効果予測を見据えた肝細胞癌の腫瘍微小環境の解析と分類について2021
- Author(s)
  紅林泰, 辻川華子, 尾島英知, 坂元亨宇
- Organizer
  第57回日本肝癌研究会（鹿児島）
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌における免疫微小環境の病理学的多様性について2021
- Author(s)
  紅林泰
- Organizer
  第57回日本肝癌研究会（鹿児島）
- Invited
- Data Source
  KAKENHI-PROJECT-21K15407
[Presentation] 肝細胞癌において、組織学的・分子生物学的分類に加えて免疫微小環境を評価する意義について2018
- Author(s)
  紅林泰、尾島英知、辻川華子、久保田直人、前原純樹、坂元亨宇
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H07089

1. UENO Akihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kurebayashi Yutaka 紅林 泰

Research Projects

Research Products

Co-Researchers

空間的遺伝子発現解析を用いたヒトに特徴的な腫瘍微小環境の全体像の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Histopathological classification of the immune microenvironment of hepatocellular carcinoma including all clinical stagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of immune microenvironment in hepatocellular carcinoma (HCC)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chronological changes in etiology, pathological and imaging findings in primary liver cancer from 2001 to 20202025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An organoid library unveils subtype-specific IGF-1 dependency via a YAP-AP1 axis in human small cell lung cancer2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular Classification of Hepatocellular Carcinoma based on Zoned Metabolic Feature and Oncogenic Signaling Pathway2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Macrotrabecular hepatocellular carcinoma: Unique immunovascular characteristics2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatial Dynamics of T- and B-Cell Responses Predicts Clinical Outcome of Resectable and Unresectable Hepatocellular Carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vessels encapsulating tumor clusters contribute to the intratumor heterogeneity of HCC on Gd-EOB-DTPA?enhanced MRI2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparative Immunohistochemical Analysis of Clinicopathological Subgroups in Hepatocellular Carcinomas from Japan and Indonesia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunovascular microenvironment in relation to prognostic heterogeneity of WNT/β‐catenin‐activated hepatocellular carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor steatosis and glutamine synthetase expression in patients with advanced hepatocellular carcinoma receiving atezolizumab plus bevacizumab therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunovascular classification of HCC reflects reciprocal interaction between immune and angiogenic tumor microenvironments2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Landscape of immune microenvironment in hepatocellular carcinoma and its additional impact on histological and molecular classification.2018

Author(s)

Journal Title

Kurebayashi Yutaka 紅林泰

[Presentation] 肝細胞癌の腫瘍微小環境と免疫療法の治療効果の関係について2024

[Presentation] 特別企画9 キャリア支援・ダイバーシティ推進委員会第２部：論文アクセプト体験記～トップジャーナルに挑む～2022