Ishizuka Shinya 石塚真哉

Researcher Number	40813316
Affiliation (Current)	2025: 名古屋大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 名古屋大学, 医学部附属病院, 講師 2018 – 2021: 名古屋大学, 医学部附属病院, 病院助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator ヒアルロン酸 / 変形性膝関節症 / HAS2 / DMM / マウス / HAS２ / Hyaluronan / Osteoarthritis / 4-MU Except Principal Investigator orthopaedic disease … More / drug repositioning / 健康長寿 / 長期縦断研究 / 地域住民健診 / 認知機能評価 / 要介護 / 死亡 / 疫学研究 / ロコモーティブ症候群 / 地域在住高齢者 / 認知機能検診 / 運動機能検診 / 生活習慣アンケート評価 / 血液生化学評価 / 死亡と介護の頻度 / 高次脳機能評価 / 運動機能評価 Less

ヒアルロン酸合成酵素の遺伝子導入による新たな変形性膝関節症の治療に向けてPrincipal Investigator
- Principal Investigator
  
  石塚真哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
整形外科領域の新規治療に向けたdrug repositioning戦略
- Principal Investigator
  
  今釜史郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
Long-term follow-up study of mortality and social care for community living eldery peoples
- Principal Investigator
  
  長谷川幸治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kansai University of Welfare Sciences
ヒアルロン酸合成酵素の遺伝子導入による新たな変形性膝関節症の治療に向けてPrincipal Investigator
- Principal Investigator
  
  石塚真哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
For treatment of knee osteoarthritis with HAS2 transgenePrincipal Investigator
- Principal Investigator
  
  Ishizuka Shinya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2019

All Journal Article Presentation

[Journal Article] Association between locomotive syndrome and fall risk in the elderly individuals in Japan: The Yakumo study.2024
- Author(s)
  Iida H, Seki T, Takegami Y, Osawa Y, Kato D, Takemoto G, Ando K, Ishizuka S, Hasegawa Y, Imagama S
- Journal Title
  
  .J Orthop Sci. 2024 Jan;29(1):327-333.
  
  Volume: 29 Issue: 1 Pages: 327-333
- DOI
  10.1016/j.jos.2022.11.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09388, KAKENHI-PROJECT-22K11853
[Journal Article] Do Postural and Walking Stabilities Change over a Decade by Aging? A Longitudinal Study.2024
- Author(s)
  Segi N, Nakashima H, Ito S, Ouchida J, Oishi R, Yamauchi I, Miyairi Y, Morita Y, Takegami Y, Ishizuka S, Seki T, Hasegawa Y, Imagama S.
- Journal Title
  
  J Clin Med.
  
  Volume: 13 Issue: 4 Pages: 1081-1081
- DOI
  10.3390/jcm13041081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09388, KAKENHI-PROJECT-22K11853
[Journal Article] Obesity Is Associated with Asymptomatic Vertebral Fractures: A Yakumo Study.2024
- Author(s)
  Miyairi Y, Nakashima H, Ito S, Segi N, Ouchida J, Oishi R, Yamauchi I, Machino M, Seki T, Ishizuka S, Takegami Y, Hasegawa Y, Imagama S.
- Journal Title
  
  J Clin Med.
  
  Volume: 13 Issue: 7 Pages: 2063-2063
- DOI
  10.3390/jcm13072063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09388
[Journal Article] Association between Locomotive Syndrome and Hearing Loss in Community-Dwelling Adults.2023
- Author(s)
  Ito S, Nakashima H, Segi N, Ouchida J, Ishizuka S, Takegami Y, Yoshida T, Hasegawa Y, Imagama S.
- Journal Title
  
  J Clin Med.
  
  Volume: 12 Issue: 17 Pages: 5626-5626
- DOI
  10.3390/jcm12175626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09388
[Journal Article] The prevalence and characteristics of diffuse idiopathic skeletal hyperostosis in the community-living middle-aged and elderly population: The Yakumo study.2023
- Author(s)
  Ohshima K, Nakashima H, Segi N, Ito S, Ouchida J, Takegami Y, Ishizuka S, Hasegawa Y, Imagama S.
- Journal Title
  
  J Orthop Sci. 2023 Oct 21:S0949-2658(23)00277-4.
  
  Volume: 29 Issue: 6 Pages: 277-277
- DOI
  10.1016/j.jos.2023.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09388
[Journal Article] Comparison of the Relationship between Visual Acuity and Motor Function in Non-Elderly and Elderly Adults2023
- Author(s)
  Sadayuki Ito, Hiroaki Nakashima, Masaaki Machino, Naoki Segi, Shinya Ishizuka, Yasuhiko Takegami, Jun Takeuchi, Jun Ouchida, Yukiharu Hasegawa, Shiro Imagama
- Journal Title
  
  J Clin Med.
  
  Volume: 1２(5): 2008. Issue: 5 Pages: 2008-2008
- DOI
  10.3390/jcm12052008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09388, KAKENHI-PROJECT-18K09048, KAKENHI-PROJECT-18K09102
[Journal Article] Circulating miRNA-122 is associated with knee osteoarthritis progression: A 6-year longitudinal cohort study in the Yakumo study.2023
- Author(s)
  Funahashi H, Takegami Y, Osawa Y, Nakashima H, Ishizuka S, Fujii R, Yamada H, Suzuki K, Hasegawa Y, Imagama S.
- Journal Title
  
  J Orthop Sci.
  
  Volume: 23 Issue: 6 Pages: 276-276
- DOI
  10.1016/j.jos.2023.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09388
[Journal Article] Metabolic syndrome reduces spinal range of motion: The Yakumo study2023
- Author(s)
  Kanbara Shunsuke、Ando Kei、Kobayashi Kazuyoshi、Nakashima Hiroaki、Machino Masaaki、Seki Taisuke、Ishizuka Shinya、Ito Sadayuki、Inoue Taro、Yamaguchi Hidetoshi、Koshimizu Hiroyuki、Segi Naoki、Tomita Hiroyuki、Hasegawa Yukiharu、Imagama Shiro
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 28 Issue: 3 Pages: 547-553
- DOI
  10.1016/j.jos.2022.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09102, KAKENHI-PROJECT-22K09388, KAKENHI-PROJECT-22K11853
[Journal Article] Nutritional Influences on Locomotive Syndrome.2022
- Author(s)
  Sadayuki Ito, Hiroaki Nakashima, Kei Ando, Masaaki Machino, Taisuke Seki, Shinya Ishizuka, Yasuhiko Takegami, Kenji Wakai, Yukiharu Hasegawa, Shiro Imagama.
- Journal Title
  
  J Clin Med. 2022 Feb; 11(3): 610.
  
  Volume: 11 Issue: 3 Pages: 610-610
- DOI
  10.3390/jcm11030610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09048, KAKENHI-PROJECT-18K09102, KAKENHI-PROJECT-22K09388
[Journal Article] Spinopelvic Imbalance Is Associated With Increased Sway in the Center of Gravity: Validation of the “Cone of Economy” Concept in Healthy Subjects2021
- Author(s)
  Segi Naoki、Nakashima Hiroaki、Ando Kei、Kobayashi Kazuyoshi、Seki Taisuke、Ishizuka Shinya、Takegami Yasuhiko、Machino Masaaki、Ito Sadayuki、Koshimizu Hiroyuki、Tomita Hiroyuki、Hasegawa Yukiharu、Imagama Shiro
- Journal Title
  
  Global Spine Journal
  
  Volume: 26 Issue: 6 Pages: 1-8
- DOI
  10.1177/21925682211038897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09102, KAKENHI-PROJECT-22K09388, KAKENHI-PROJECT-22K11853
[Journal Article] 4-Methylumbelliferone suppresses catabolic activation in anterior cruciate ligament-derived cells via a mechanism independent of hyaluronan inhibition2021
- Author(s)
  Masaru Idota ,Shinya Ishizuka ,et al.
- Journal Title
  
  J Orthop Surg Res .
  
  Volume: 16 Issue: 1 Pages: 507-507
- DOI
  10.1186/s13018-021-02637-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16652
[Journal Article] Hyaluronan synthase 2 (HAS2) overexpression diminishes the procatabolic activity of chondrocytes by a mechanism independent of extracellular hyaluronan.2019
- Author(s)
  Ishizuka S, Tsuchiya S, Ohashi Y, Terabe K, Askew EB, Ishizuka N, Knudson CB, Knudson W.
- Journal Title
  
  J Biol Chem
  
  Volume: 294 Issue: 37 Pages: 13562-13579
- DOI
  10.1074/jbc.ra119.008567
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16655
[Presentation] Effects Of Hyaluronan Synthase 2 (HAS2) Gene Transfer In A Mouse Model Of Knee Osteoarthritis2024
- Author(s)
  Sei Fujii,Shinya Ishizuka
- Organizer
  Orthopaedic research society 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16652
[Presentation] 加齢による筋力低下が運動機能に及ぼす影響　Yakumo study.2022
- Author(s)
  伊藤定行、安藤圭、中島宏彰、町野正明、関泰輔、石塚真哉、竹上靖彦、長谷川幸治、今釜史郎
- Organizer
  第９５回日本整形外科学術総会
- Data Source
  KAKENHI-PROJECT-22K09388
[Presentation] 一般住民の転倒リスク　ロコモ、フレイルの相関．2022
- Author(s)
  今釜史郎、安藤圭、中島宏彰、町野正明、伊藤定行、関泰輔、石塚真哉、世木直喜、長谷川幸治
- Organizer
  第９５回日本整形外科学術総会
- Data Source
  KAKENHI-PROJECT-22K09388
[Presentation] 一般中高齢者におけるロコモ度テスト　転倒第９５回日本整形外科学術総会や重心動揺のロコモ度別評価.2022
- Author(s)
  今釜史郎、安藤圭、中島宏彰、町野正明、伊藤定行、関泰輔、竹上靖彦、大澤郁介、石塚真哉、世木直喜、長谷川幸治
- Organizer
  第９５回日本整形外科学術総会
- Data Source
  KAKENHI-PROJECT-22K09388
[Presentation] 高齢者における聴力とロコモの関連2022
- Author(s)
  伊藤定行、今釜史郎、安藤圭、中島宏彰、町野正明、伊藤定行、関泰輔、竹上靖彦、大澤郁介、石塚真哉、世木直喜、長谷川幸治安藤圭、中島宏彰、町野正明、関泰輔、石塚真哉、竹上靖彦、長谷川幸治、今釜史郎
- Organizer
  第５１回日本脊椎脊髄病学会
- Data Source
  KAKENHI-PROJECT-22K09388
[Presentation] Anti-inflammatory effect of 4-methylumbelliferone (4-MU) in human ACL-derived cells2021
- Author(s)
  Idota M, Ishizuka S
- Organizer
  2021 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16655
[Presentation] ヒト前十字靱帯由来細胞における4-Methylumbelliferone(4-MU)およびヒアルロン酸合成酵素2(HAS2)過剰発現による抗炎症作用2021
- Author(s)
  井戸田大, 平岩秀樹, 石塚真哉
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K16655
[Presentation] HAS2 Overexpression in Chondrocytes Downregulates Cytokine Activated Metabolism2019
- Author(s)
  Saho Tsuchiya, Shinya Ishizuka, Warren Knudson
- Organizer
  Orthpaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16655
[Presentation] HAS2 Overexpression in Chondrocytes Downregulates Cytokine Activated Metabolism2019
- Author(s)
  Saho Tsuchiya, Shinya Ishizuka, Kenya Terabe, Yoshifumi Ohashi, Naoko Ishizuka, Emily B. Askew, Cheryl B. Knudson, Warren Knudson
- Organizer
  2019 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16655

1. 今釜史郎 (40467288)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. 長谷川幸治 (50208500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. 八田武志 (80030469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 坂口健史 (00896053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 寺部健哉 (10816870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大羽宏樹 (20837314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三島健一 (40646519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹上靖彦 (50755345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松下雅樹 (60721115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中島宏彰 (70710101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ANDO Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 小林和克

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ishizuka Shinya 石塚 真哉

Research Projects

Research Products

Co-Researchers

ヒアルロン酸合成酵素の遺伝子導入による新たな変形性膝関節症の治療に向けてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

整形外科領域の新規治療に向けたdrug repositioning戦略

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Long-term follow-up study of mortality and social care for community living eldery peoples

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒアルロン酸合成酵素の遺伝子導入による新たな変形性膝関節症の治療に向けてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

For treatment of knee osteoarthritis with HAS2 transgenePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Association between locomotive syndrome and fall risk in the elderly individuals in Japan: The Yakumo study.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Do Postural and Walking Stabilities Change over a Decade by Aging? A Longitudinal Study.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Obesity Is Associated with Asymptomatic Vertebral Fractures: A Yakumo Study.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between Locomotive Syndrome and Hearing Loss in Community-Dwelling Adults.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The prevalence and characteristics of diffuse idiopathic skeletal hyperostosis in the community-living middle-aged and elderly population: The Yakumo study.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of the Relationship between Visual Acuity and Motor Function in Non-Elderly and Elderly Adults2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circulating miRNA-122 is associated with knee osteoarthritis progression: A 6-year longitudinal cohort study in the Yakumo study.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic syndrome reduces spinal range of motion: The Yakumo study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nutritional Influences on Locomotive Syndrome.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spinopelvic Imbalance Is Associated With Increased Sway in the Center of Gravity: Validation of the “Cone of Economy” Concept in Healthy Subjects2021

Ishizuka Shinya 石塚真哉

[Presentation] 加齢による筋力低下が運動機能に及ぼす影響　Yakumo study.2022

[Presentation] 一般住民の転倒リスク　ロコモ、フレイルの相関．2022

[Presentation] 一般中高齢者におけるロコモ度テスト　転倒第９５回日本整形外科学術総会や重心動揺のロコモ度別評価.2022