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SHIMONOSONO Masataka  下之薗 将貴

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Shimonosono Masataka  下之薗 将貴

下之薗 将貴  シモノソノ マサタカ

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Researcher Number 40814322
Affiliation (Current) 2025: 鹿児島大学, 医歯学域医学系, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 鹿児島大学, 鹿児島大学病院, 医員
2018: 鹿児島大学, 附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related / 0901:Oncology and related fields
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords
Principal Investigator
オルガノイド / 食道癌 / 薬剤スクリーニング / 発癌 / 食道扁平上皮癌 / オルガノイド培養 / 遺伝子プロファイル / 薬剤感受性試験 / 遺伝子解析
Except Principal Investigator
ゲノム … More / 膵癌 / 胃癌 / リキッドバイオプシー診断 / マイクロ流体チップ / オルガノイド / コンパニオン診断 / ポリマーCTCチップ / Circulating Tumor Cell / 循環腫瘍細胞 / リキッドバイオプシー / 遺伝子変異 / リスク低減 / マイクロバーオーム / 消化器癌治療耐性因子 / ATAC-seq / クロマチン変化 / マイクロバイオ―タ / IPMN / 細菌叢 / マイクロバイオータ / 早期診断 / 発癌 Less
  • Research Projects

    (7 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (16 People)
  •  High-throughput drug screening realize a precision medicine for esophageal cancerPrincipal Investigator

    • Principal Investigator
      下之薗 将貴
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  クロマチン変化の時間軸に着目した消化器癌治療耐性因子の解明

    • Principal Investigator
      喜多 芳昭
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  Would comprehensive analyses of genome and microbiome establish the strategy for decreasing the risk of pancreatic cancer?

    • Principal Investigator
      大塚 隆生
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  Liquid Biopsy Diagnosis Using Microfluidic Chip Technology Revolutionizes Gastric Cancer Treatment

    • Principal Investigator
      有上 貴明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  Why does whole pancreas become risk zone for cancer development? Assessment of microbiota and the challenge for early diagnosis of pancreatic cancer.

    • Principal Investigator
      大塚 隆生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kagoshima University
  •  Esophageal cancer organoid culture leads to the developement of new drug to prevent the occurrence of cancerPrincipal Investigator

    • Principal Investigator
      Shimonosono Masataka
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Kagoshima University
  •  食道扁平上皮癌オルガノイド・マイクロRNA解析による治療抵抗性分子経路の解明Principal Investigator

    • Principal Investigator
      下之薗 将貴
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-132024

    • Author(s)
      Masuda Mia Y.、Shimonosono Masataka、Flashner Samuel、Morimoto Masaki、Pai Rish K.、Rank Matthew A.、Nakagawa Hiroshi、Kita Hirohito、Wright Benjamin L.、Doyle Alfred D.
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: - Issue: 5 Pages: 1355-1368

    • DOI

      10.1016/j.jaci.2024.01.017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] Evaluation of Quality of Life and Prognosis of Gastric Cancer Patients After Laparoscopic Subtotal Gastrectomy2023

    • Author(s)
      SHIMONOSONO MASATAKA、ARIGAMI TAKAAKI、MATSUSHITA DAISUKE、TSURUDA YUSUKE、SASAKI KEN、BABA KENJI、UCHIKADO YASUTO、KURAHARA HIROSHI、OHTSUKA TAKAO
    • Journal Title

      Anticancer Research

      Volume: 44 Issue: 1 Pages: 387-396

    • DOI

      10.21873/anticanres.16823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment2023

    • Author(s)
      Flashner Samuel、Shimonosono Masataka、Tomita Yasuto、Matsuura Norihiro、Ohashi Shinya、Muto Manabu、Klein-Szanto Andres J、Alan Diehl J、Chen Che-Hong、Mochly-Rosen Daria、Weinberg Kenneth I、Nakagawa Hiroshi
    • Journal Title

      Carcinogenesis

      Volume: 45 Issue: 1-2 Pages: 95-106

    • DOI

      10.1093/carcin/bgad085

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis2022

    • Author(s)
      Takeo Hara, Yuta Kasagi, Joshua Wang, Masaru Sasaki, Bailey Aaron, Adam Karami, Masataka Shimonosono, Rieko Shimonosono, Hisatsugu Maekawa, Lauren Dolinsky, Benjamin Wilkins, Jeremy Klein, Jane Wei, Kathryn Nunes, Kristle Lynch, Kathryn E Hamilton, Tatiana A Karakasheva, Kelly A Whelan, Hiroshi Nakagawa, Amanda B Muir
    • Journal Title

      Cellular and Molecular Gastroenterology and Hepatology

      Volume: 13 Issue: 5 Pages: 1449-1467

    • DOI

      10.1016/j.jcmgh.2022.01.018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma2021

    • Author(s)
      Angela J Yoon, Regina M Santella, Shuang Wang, David I Kutler, Richard D Carvajal, Elizabeth Philipone, Tian Wang, Scott M Peters, Claire R Stewart, Fatemeh Momen-Heravi, Scott Troob, Matt Levin, Zohreh AkhavanAghdam, Austin J Shackelford, Carleigh R Canterbury, Masataka Shimonosono, Hiroshi Nakagawa
    • Journal Title

      Journal of Oncology

      Volume: 2021 Pages: 1-11

    • DOI

      10.1155/2021/8292453

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy2021

    • Author(s)
      Shimonosono Masataka、Tanaka Koji、Flashner Samuel、Takada Satoshi、Matsuura Norihiro、Tomita Yasuto、Sachdeva Uma M.、Noguchi Eishi、Sangwan Veena、Ferri Lorenzo、Momen-Heravi Fatemeh、Yoon Angela J.、Klein-Szanto Andres J.、Diehl J. Alan、Nakagawa Hiroshi
    • Journal Title

      Biomolecules

      Volume: 11 Issue: 10 Pages: 1479-1479

    • DOI

      10.3390/biom11101479

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] Understanding the cellular origin and progression of esophageal cancer using esophageal organoids2021

    • Author(s)
      Sachdeva Uma M.、Shimonosono Masataka、Flashner Samuel、Cruz-Acuna Ricardo、Gabre Joel T.、Nakagawa Hiroshi
    • Journal Title

      Cancer Letters

      Volume: 509 Pages: 39-52

    • DOI

      10.1016/j.canlet.2021.03.031

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Journal Article] Clinical impact of creatine phosphokinase and c-reactive protein as predictors of postgastrectomy complications in patients with gastric cancer2021

    • Author(s)
      Okubo Keishi、Arigami Takaaki、Matsushita Daisuke、Kijima Takashi、Shimonosono Masataka、Uenosono Yoshikazu、Yanagita Shigehiro、Kurahara Hiroshi、Mori Shinichiro、Ohtsuka Takao、Natsugoe Shoji
    • Journal Title

      BMC Cancer

      Volume: 21 Issue: 1 Pages: 95-95

    • DOI

      10.1186/s12885-021-07801-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20842
  • [Presentation] アルコール暴露は頭頸部・食道癌腫瘍内でオートファジー活性の高い癌幹細胞分画の増加を誘導する2022

    • Author(s)
      下之薗将貴
    • Organizer
      日本外科学会総会
    • Data Source
      KAKENHI-PROJECT-21K20842
  • 1.  大塚 隆生 (20372766)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  関 直彦 (50345013)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  谷本 昭英 (10217151)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  杉浦 剛 (40322292)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  田上 聖徳 (50721031)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  松下 大輔 (10724205)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  夏越 祥次 (70237577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  蔵原 弘 (70464469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  喜多 芳昭 (30570692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  馬場 研二 (30642615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  鶴田 祐介 (70812767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  和田 真澄 (60836112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  井手野 昇 (90883421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  有上 貴明 (40527058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  大永 崇 (10416133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  中嶋 太極 (30974646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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