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KITANO YUKI  北野 雄希

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Kitano Yuki  北野 雄希

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Researcher Number 40814760
Other IDs
Affiliation (Current) 2025: 熊本大学, 病院, 特任助教
Affiliation (based on the past Project Information) *help 2023 – 2025: 熊本大学, 病院, 特任助教
2022: 熊本大学, 大学院生命科学研究部(医), 特定研究員
2019: 熊本大学, 病院, 非常勤診療医師
2018: 熊本大学, 医学部附属病院, 非常勤診療医師
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
腫瘍免疫 / がん代謝 / PGC1α / MYC / 癌代謝 / 肝細胞癌 / CD8 T細胞 / 膵癌 / CD8+ T細胞 / PD-L1 … More / Nrf2 / 肝胆膵領域癌 / バイオマーカー / 免疫チェックポイント … More
Except Principal Investigator
lactate / neural cells / LDHA / tumor microenvironment / pancratic cancer / バイオマーカー / 予後 / Molecular gene signature / 膵癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (15 People)
  •  Examination of metabolic remodeling in pancreatic cancer microenvironment for therapeutic strategies

    • Principal Investigator
      北村 文優
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kumamoto University
  •  Gene signatureによる膵癌化学療法の治療効果予測及び新規治療標的の検証

    • Principal Investigator
      中川 茂樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kumamoto University
  •  Development of Innovative Hepatocellular Carcinoma Therapies Targeting Cancer Metabolism and Tumor Immunity Regulated by MYC and PGC1aPrincipal Investigator

    • Principal Investigator
      Kitano Yuki
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kumamoto University
  •  Functional analysis and development of novel treatment targeting for Nrf2 in hapatobiliary pancreatic cancerPrincipal Investigator

    • Principal Investigator
      Kitano Yuki
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kumamoto University

All 2022 2019 2018 2017

All Journal Article

  • [Journal Article] Cancer-associated fibroblast senescence and its relation with tumour-infiltrating lymphocytes and PD-L1 expressions in intrahepatic cholangiocarcinoma2022

    • Author(s)
      2.Lan C, Kitano Y, Yamashita YI, Yamao T, Kajiyama K, Yoshizumi T, Fukuzawa K, Sugimachi K, Ikeda Y, Takamori H, Miyanari N, Hirota M, Baba H
    • Journal Title

      British Journal of Cancer

      Volume: 126 Issue: 2 Pages: 219-227

    • DOI

      10.1038/s41416-021-01569-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15545, KAKENHI-PROJECT-21K15534
  • [Journal Article] Survival impact of immune cells infiltrating peritumoral area of hepatocellular carcinoma2022

    • Author(s)
      Yusa Toshihiko、Yamashita Yo‐ichi、Okabe Hirohisa、Nakao Yosuke、Itoyama Rumi、Kitano Yuki、Kaida Takayoshi、Miyata Tatsunori、Mima Kosuke、Imai Katsunori、Hayashi Hiromitsu、Baba Hideo
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 12 Pages: 4048-4058

    • DOI

      10.1111/cas.15437

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08829, KAKENHI-PROJECT-22K15545
  • [Journal Article] Conophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts2019

    • Author(s)
      N. Ishii, K. Araki, T. Yokobori, K. Hagiwara, G. Dolgormaa, T. Yamanaka, T. Handa, M. Tsukagoshi, T. Igarashi, A. Watanabe, N. Kubo, N. Harimoto, A. Masamune, K. Umezawa, H. Kuwano, K. Shirabe
    • Journal Title

      Cancer Science

      Volume: 10 Issue: 1 Pages: 334-434

    • DOI

      10.1111/cas.13874

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K01967, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-17K10704
  • [Journal Article] Clinical significance of preoperative hepatocellular carcinoma with high lens culinaris agglutinin-reactive fraction of alpha-fetoprotein, but low alpha-fetoprotein.2019

    • Author(s)
      Yamao T, Yamashita Y, Imai K, Umezaki N, Tsukamoto M, Kitano Y, Arima K, Miyata T, Nakagawa S, Okabe H, Hayashi H, Chikamoto A, Ishiko T, Baba H
    • Journal Title

      Anticancer Res

      Volume: 39(2) Issue: 2 Pages: 883-889

    • DOI

      10.21873/anticanres.13189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] A case of acute perforated cholecystitis with intracystic tumor thrombus of hepatocellular carcinoma.2019

    • Author(s)
      Nakao Y, Okabe H, Yamashita Y, Itoyama R, Yusa T, Kitano Y, Arima K, Miyata T, Nakagawa S, Imai K, Chikamoto A, Baba H
    • Journal Title

      Int Canc Conf J

      Volume: 8(1) Pages: 43-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Clinical Significance of PD-L1 Expression in Both Cancer and Stroma Cells of Cholangiocarcinoma Patients2019

    • Author(s)
      Kitano Yuki、Yamashita Yo-ichi、Nakao Yosuke、Itoyama Rumi、Yusa Toshihiko、Umezaki Naoki、Tsukamoto Masayo、Yamao Takanobu、Miyata Tatsunori、Nakagawa Shigeki、Okabe Hirohisa、Imai Katsunori、Chikamoto Akira、Ishiko Takatoshi、Baba Hideo
    • Journal Title

      Annals of Surgical Oncology

      Volume: 27 Issue: 2 Pages: 599-607

    • DOI

      10.1245/s10434-019-07701-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Clinical role of fludeoxyglucose (18F) positron emission tomography/computed tomography ((18)F-FDG PET/CT) in patients with pancreatic neuroendocrine tumors.2019

    • Author(s)
      Matsumoto T, Okabe H, Yamashita Y, Yusa T, Itoyama R, Nakao Y, Yamao T, Umzaki N, Tsukamoto M, Kitano Y, Miyata T, Arima K, Nitta H, Hayashi H, Imai K, Chikamoto A, Baba H
    • Journal Title

      Surg Today

      Volume: 49(1) Issue: 1 Pages: 21-26

    • DOI

      10.1007/s00595-018-1703-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Multidisciplinary approach of liver metastases from colorectal cancer.2019

    • Author(s)
      Adam R, Kitano Y
    • Journal Title

      Ann Gastroenterol Surg

      Volume: 3 Issue: 1 Pages: 50-56

    • DOI

      10.1002/ags3.12227

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Effectiveness of surgery for recurrent cholangiocarcinoma: A single center experience and brief literature review2019

    • Author(s)
      Kitano Yuki、Yamashita Yo-ichi、Nakagawa Shigeki、Okabe Hirohisa、Imai Katsunori、Chikamoto Akira、Baba Hideo
    • Journal Title

      The American Journal of Surgery

      Volume: 219 Issue: 1 Pages: 175-180

    • DOI

      10.1016/j.amjsurg.2019.02.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] A case of 15-year recurrence-free survival after microwave coagulation therapy for liver metastasis from gastric cancer.2018

    • Author(s)
      Kinoshita K, Beppu T, Miyata T, Kuramoto K, Yoshida Y, Umesaki N, Kitano Y, Nakagawa S, Okabe H, Nitta H, Imai K, Hayashi H, Yamashita Y, Komori H, Horino K, Misumi A, Baba H
    • Journal Title

      Anticancer Res

      Volume: 38(3) Pages: 1595-1598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Controlling Nutritional Status (CONUT) score is a prognostic marker for gastric cancer patients after curative resection. Gastric Cancer.2018

    • Author(s)
      Kuroda D, Sawayama H, Kurashige J, Iwatsuki M, Eto T, Tokunaga R, Kitano Y, Yamamura K, Ouchi M, Nakamura K, Baba Y, Sakamoto Y, Yamashita Y, Yoshida N, Chikamoto A, Baba H
    • Journal Title

      Gastric Cancer.

      Volume: 21(2) Issue: 2 Pages: 204-212

    • DOI

      10.1007/s10120-017-0744-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19942, KAKENHI-PROJECT-18K16261, KAKENHI-PROJECT-18K16370
  • [Journal Article] Hepatic resection followed by hepatic arterial infusion chemotherapy for hepatocellular carcinoma with intrahepatic dissemination.2018

    • Author(s)
      Kuramoto K, Beppu T, Nitta H, Imai K, Masuda T, Miyata T, Koga Y, Kitano Y, Kaida T, Nakagawa S, Okabe H, Hayashi H, Hashimoto D, Yamashita Y, Chikamoto A, Kikuchi K, Baba H
    • Journal Title

      Anticancer Res

      Volume: 38(1) Pages: 525-531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Cystic gastric metastasis from pancreatic cancer.2018

    • Author(s)
      Umezaki N, Hashimoto D, Nakagawa S, Yamao T, Tsukamoto M, Kitano Y, Arima K, Yamamura K, Miyata T, Okabe H, Chikamoto A, Matsumura F, Baba H
    • Journal Title

      Surg Case Rep

      Volume: 4(1) Issue: 1 Pages: 31-31

    • DOI

      10.1186/s40792-018-0443-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Prognostic value of LINE-1 methylation level in 321 patients with primary liver cancer including hepatocellular carcinoma and intrahepatic cholangiocarcinoma.2018

    • Author(s)
      Miyata T, Yamashita Y, Baba Y, Harada K, Yamao T, Umezaki N, Tsukamoto M, Kitano Y, Yamamura K, Arima K, Nakagawa S, Okabe H, Imai K, Hashimoto D, Chikamoto A, Shimokawa M, Baba H
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 29 Pages: 20795-20806

    • DOI

      10.18632/oncotarget.25124

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10104, KAKENHI-PROJECT-16K19944, KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-18K16370
  • [Journal Article] Predicting Poorly Differentiated Hepatocellular Carcinoma that Meets the Milan Criteria2018

    • Author(s)
      KOGA YUKI、BEPPU TORU、MIYATA TATSUNORI、KITANO YUKI、TSUJI AKIRA、NAKAGAWA SHIGEKI、ARIMA KOTA、KURAMOTO KUNITAKA、OKABE HIROHISA、IMAI KATSUNORI、HAYASHI HIROMITSU、NITTA HIDETOSHI、YAMASHITA YO-ICHI、CHIKAMOTO AKIRA、ISHIKO TAKATOSHI、BABA HIDEO
    • Journal Title

      Anticancer Research

      Volume: 38 Issue: 7 Pages: 4093-4099

    • DOI

      10.21873/anticanres.12699

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-18K16370
  • [Journal Article] Tumor-infiltrating inflammatory and immune cells in patients with extrahepatic cholangiocarcinoma.2018

    • Author(s)
      Kitano Y, Okabe H, Yamashita YI, Nakagawa S, Saito Y, Umezaki N, Tsukamoto M, Yamao T, Yamamura K, Arima K, Kaida T, Miyata T, Mima K, Imai K, Hashimoto D, Komohara Y, Chikamoto A, Ishiko T, Baba H
    • Journal Title

      Br J Cancer

      Volume: 118(2) Issue: 2 Pages: 171-180

    • DOI

      10.1038/bjc.2017.401

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19936, KAKENHI-PROJECT-18K16369, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-17K16570
  • [Journal Article] Multiple primary cancers in patients with pancreatic cancer.2018

    • Author(s)
      Yamamura K, Hashimoto D, Kitano Y, Kuroda D, Eto T, Arima K, Kaida T, Miyata T, Nakagawa S, Imai K, Yamashita Y, Chikamoto A, Matsumura F, Baba H
    • Journal Title

      Am Surg

      Volume: 84(12)

    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Complete remission of advanced hepatocellular carcinoma following transient chemoembolization and portal vein ligation.2018

    • Author(s)
      Koga Y, Beppu T, Imai K, Kuramoto K, Miyata T, Kitano Y, Nakagawa S, Okabe H, Okabe K, Yamashita Y, Chikamoto A, Baba H
    • Journal Title

      Surg Case Rep

      Volume: 4(1) Issue: 1 Pages: 102-102

    • DOI

      10.1186/s40792-018-0510-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K16370
  • [Journal Article] Enhancer of zeste homolog 2 (EZH2) regulates tumor angiogenesis and predicts recurrence and prognosis of intrahepatic cholangiocarcinoma2018

    • Author(s)
      Nakagawa Shigeki、Okabe Hirohisa、Ouchi Mayuko、Tokunaga Ryuma、Umezaki Naoki、Higashi Takaaki、Kaida Takatoshi、Arima Kota、Kitano Yuki、Kuroki Hideyuki、Mima Kosuke、Nitta Hidetoshi、Imai Katsunori、Hashimoto Daisuke、Yamashita Yo-ichi、Chikamoto Akira、Baba Hideo
    • Journal Title

      HPB

      Volume: 20 Issue: 10 Pages: 939-948

    • DOI

      10.1016/j.hpb.2018.03.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-18K16369, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16K19939
  • [Journal Article] Number of acinar cells at the pancreatic stump predicts pancreatic fistula after pancreaticoduodenectomy.2018

    • Author(s)
      Umezaki N, Hashimoto D, Nakagawa S, Kitano Y, Yamamura K, Chikamoto A, Matsumura F, Baba H
    • Journal Title

      Surg Today

      Volume: 48(8) Issue: 8 Pages: 790-795

    • DOI

      10.1007/s00595-018-1656-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16K10604
  • [Journal Article] Microvascular invasion of single small hepatocellular carcinoma ?3 cm: Predictors and optimal treatments2018

    • Author(s)
      Yamashita Yo-ichi、Imai Katsunori、Yusa Toshihiko、Nakao Yosuke、Kitano Yuki、Nakagawa Shigeki、Okabe Hirohisa、Chikamoto Akira、Ishiko Takatoshi、Yoshizumi Tomoharu、Aishima Shinichi、Maehara Yoshihiko、Baba Hideo
    • Journal Title

      Annals of Gastroenterological Surgery

      Volume: 2 Issue: 3 Pages: 197-203

    • DOI

      10.1002/ags3.12057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-18K16370
  • [Journal Article] Nrf2 promotes oesophageal cancer cell proliferation via metabolic reprogramming and detoxification of reactive oxygen species.2018

    • Author(s)
      Kitano Y, Baba Y, Nakagawa S, Miyake K, Iwatsuki M, Ishimoto T, Yamashita YI, Yoshida N, Watanabe M, Nakao M, Baba H.
    • Journal Title

      J Pathol.

      Volume: 244(3) Issue: 3 Pages: 346-357

    • DOI

      10.1002/path.5021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-18K16370
  • [Journal Article] Clinical usefulness of postoperative C-reactive protein/albumin ratio in pancreatic ductal adenocarcinoma.2017

    • Author(s)
      Arima K, Yamashita YI, Hashimoto D, Nakagawa S, Umezaki N, Yamao T, Tsukamoto M, Kitano Y, Yamamura K, Miyata T, Okabe H, Ishimoto T, Imai K, Chikamoto A, Baba H.
    • Journal Title

      Am J Surg.

      Volume: Aug 26 Issue: 1 Pages: 111-115

    • DOI

      10.1016/j.amjsurg.2017.08.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-17K16570
  • 1.  中川 茂樹 (10594872)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  岡部 弘尚 (40573621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  伊東山 瑠美 (50868172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  北村 文優 (90897068)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  YOSHIDA Naoya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  梅沢 一夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  澤山 浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  今井 克憲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 9.  林 洋光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  黒木 秀幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  東 孝暁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  馬場 祥史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  石本 崇胤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  遊佐 俊彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  山下 洋市
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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