MACPHERSON TOM マクファーソントム

… Alternative Names

Macpherson Tom マクファーソントム

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Researcher Number	40821898
Other IDs
Affiliation (Current)	2025: 京都大学, 薬学研究科, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 大阪大学, 蛋白質研究所, 助教 2018 – 2019: 大阪大学, 蛋白質研究所, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related Except Principal Investigator Basic Section 51020:Cognitive and brain science-related / Complex systems
Keywords	Principal Investigator Behavior / In-Vivo Imaging / Optogenetics / In-vivo imaging / Basal Ganglia / Nucleus Accumbens / Learning / Aversion / Reward Except Principal Investigator 神経回路 … More / 大脳基底核 / 精神疾患 / ドーパミン / 行動柔軟性 / ドーパミン受容体 / 腹側淡蒼球 / 大脳皮質 / 生理学 / トランスレーショナルリサーチ / 脳神経疾患 / 脳・神経 / 神経科学 / 強化学習 / 意思決定 Less

戦略的な意思決定の神経機構と精神疾患病態の解明
- Principal Investigator
  
  疋田貴俊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Osaka University
Investigation of nucleus accumbens subpopulations controlling reward and aversive learningPrincipal Investigator
- Principal Investigator
  
  Macpherson Tom
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Osaka University
Neuronal circuit mechanisms of reward/goal-directed behavior
- Principal Investigator
  
  HIKIDA Takatoshi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka University
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Dual Roles for Nucleus Accumbens Core Dopamine D1-Expressing Neurons Projecting to the Substantia Nigra Pars Reticulata in Limbic and Motor Control in Male Mice2023
- Author(s)
  Attachaipanich Suthinee、Ozawa Takaaki、Macpherson Tom、Hikida Takatoshi
- Journal Title
  
  eNeuro
  
  Volume: 10 Issue: 6 Pages: 1-12
- DOI
  10.1523/eneuro.0082-23.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18557, KAKENHI-PROJECT-23K21325, KAKENHI-PROJECT-23K22376, KAKENHI-PROJECT-23K24205
[Journal Article] Editorial: Circuit, molecular, and developmental mechanisms in decision-making behavior2023
- Author(s)
  Macpherson Tom、Niwa Minae、Morishita Hirofumi、Hikida Takatoshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 1192237-1192237
- DOI
  10.3389/fnins.2023.1192237
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-23K24205
[Journal Article] Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior in mice2023
- Author(s)
  Nishioka Tadaaki、Attachaipanich Suthinee、Hamaguchi Kosuke、Lazarus Michael、de Kerchove d’Exaerde Alban、Macpherson Tom、Hikida Takatoshi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2284-2284
- DOI
  10.1038/s41467-023-38025-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-21K15210, KAKENHI-PROJECT-23K24205, KAKENHI-PUBLICLY-22H05495, KAKENHI-PROJECT-23K21394, KAKENHI-PROJECT-21H02804
[Journal Article] Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice2023
- Author(s)
  Aomine Yoshiatsu、Oyama Yoshinobu、Sakurai Koki、Macpherson Tom、Ozawa Takaaki、Hikida Takatoshi
- Journal Title
  
  Psychopharmacology
  
  Volume: 241 Issue: 1 Pages: 89-96
- DOI
  10.1007/s00213-023-06465-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18557, KAKENHI-PROJECT-23K22376, KAKENHI-PROJECT-23K24205
[Journal Article] Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice2022
- Author(s)
  Aomine Yoshiatsu、Sakurai Koki、Macpherson Tom、Ozawa Takaaki、Miyamoto Yoichi、Yoneda Yoshihiro、Oka Masahiro、Hikida Takatoshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 1-13
- DOI
  10.3389/fnins.2022.905991
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18557, KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-21K15210, KAKENHI-PUBLICLY-21H00311, KAKENHI-PROJECT-23K22376, KAKENHI-PROJECT-23K24205
[Journal Article] Nucleus Accumbens Core Dopamine D2 Receptor-Expressing Neurons Control Reversal Learning but Not Set-Shifting in Behavioral Flexibility in Male Mice2022
- Author(s)
  Macpherson Tom、Kim Ji Yoon、Hikida Takatoshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 885380-885380
- DOI
  10.3389/fnins.2022.885380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-21K15210, KAKENHI-PROJECT-23K21325, KAKENHI-PROJECT-23K24205
[Journal Article] Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex2020
- Author(s)
  Hikida Takatoshi、Yao Shuhei、Macpherson Tom、Fukakusa Ayumi、Morita Makiko、Kimura Haruhide、Hirai Keisuke、Ando Tatsuya、Toyoshiba Hiroyoshi、Sawa Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1838-1838
- DOI
  10.1038/s41598-020-58711-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542
[Journal Article] Neurotransmission through dopamine D1 receptors is required for aversive memory formation and Arc activation in the cerebral cortex2020
- Author(s)
  Saito Nae、Tainaka Kazuki、Macpherson Tom、Hikida Takatoshi、Yamaguchi Shun、Sasaoka Toshikuni
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 58-65
- DOI
  10.1016/j.neures.2020.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04937, KAKENHI-PROJECT-20K21246, KAKENHI-PLANNED-16H06568, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02542
[Journal Article] Response to ‘Mood and Affect’2019
- Author(s)
  Macpherson Tom、Hikida Takatoshi
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 73 Issue: 6 Pages: 347-347
- DOI
  10.1111/pcn.12845
- Open Access
- Data Source
  KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542
[Journal Article] Role of basal ganglia neurocircuitry in the pathology of psychiatric disorders2019
- Author(s)
  Macpherson Tom、Hikida Takatoshi
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 印刷中 Issue: 6 Pages: 289-301
- DOI
  10.1111/pcn.12830
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14579, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542
[Journal Article] Preproenkephalin-expressing ventral pallidal neurons control inhibitory avoidance learning. 2019 (in press)2019
- Author(s)
  Macpherson T, Mizoguchi H, Yamanaka A, Hikida T
- Journal Title
  
  Neurochem Int
  
  Volume: 126 Pages: 11-18
- DOI
  10.1016/j.neuint.2019.02.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0223, KAKENHI-PLANNED-16H06568, KAKENHI-PUBLICLY-17H05563, KAKENHI-PUBLICLY-17H06053, KAKENHI-PUBLICLY-18H05124, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-16K14579, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K21811, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532
[Journal Article] Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice2019
- Author(s)
  Hikida Takatoshi、Morita Makiko、Kuroiwa Mahomi、Macpherson Tom、Shuto Takahide、Sotogaku Naoki、Niwa Minae、Sawa Akira、Nishi Akinori
- Journal Title
  
  Neuroscience Research
  
  Volume: in press Pages: 38-45
- DOI
  10.1016/j.neures.2019.02.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05135, KAKENHI-PROJECT-16K14579, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-19H03410
[Journal Article] Nucleus Accumbens Dopamine D1-Receptor-Expressing Neurons Control the Acquisition of Sign-Tracking to Conditioned Cues in Mice2018
- Author(s)
  Macpherson Tom、Hikida Takatoshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 418-418
- DOI
  10.3389/fnins.2018.00418
- NAID
  120006491925
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-16K14579
[Journal Article] 認知学習における大脳基底核神経回路機構2017
- Author(s)
  疋田貴俊、森田真規子、Macpherson Tom
- Journal Title
  
  日本神経精神薬理学雑誌
  
  Volume: 37 Pages: 35-38
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06568
[Journal Article] Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCage.2016
- Author(s)
  Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A and Hikida T.
- Journal Title
  
  Learning and Memory
  
  Volume: 23 Issue: 7 Pages: 359-364
- DOI
  10.1101/lm.042507.116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01606, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-15H04275, KAKENHI-PROJECT-15F15107, KAKENHI-PROJECT-26290029, KAKENHI-PROJECT-16K14579
[Journal Article] Neural mechanism of the nucleus accumbens circuit in reward and aversive learning.2016
- Author(s)
  Hikida T, Morita M, Macpherson T
- Journal Title
  
  Neurosci. Res.
  
  Volume: - Pages: 1-5
- DOI
  10.1016/j.neures.2016.01.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23120011, KAKENHI-PROJECT-15F15107, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-15H04275, KAKENHI-PROJECT-16K14579
[Presentation] 恐怖条件づけ中のマウス脳内における領域特異的なドーパミン放出動態2024
- Author(s)
  小澤貴明、梅本和宏、中村萌、岩本涼太郎、松本悠真、柴田智弘、尾山賀信、マクファーソン　トム、疋田貴俊
- Organizer
  第101回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] アルコール関連行動異常を引き起こす核ー細胞質間輸送メカニズム2024
- Author(s)
  青峰良淳、櫻井航輝、マクファーソントム、小澤貴明、宮本洋一、米田悦啓、岡正啓、疋田貴俊.
- Organizer
  第46回日本分子生物学会年会.
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Dual roles for nucleus accumbens core dopamine D1-expressing neurons projecting to the substantia nigra pars reticulata in limbic and motor control2023
- Author(s)
  Suthinee Attachaipanich, Takaaki Ozawa, Tom Macpherson, Takatoshi Hikida
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior.2023
- Author(s)
  Tom Macpherson, Tadaaki Nishioka, Suthinee Attachaipanich, Kosuke Hamaguchi, Michael Lazarus, Alban de Kerchove d'Exaerde, Takatoshi Hikida.
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Extracellular sugar modification regulates neuronal signaling in the nucleus accumbens.2023
- Author(s)
  Masu M, Miya K, Masu K, Okada T, Ohta K, Macpherson T, Hikida T, Suzuki E, Momiyama T.
- Organizer
  日本生理学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Error-related signaling in D2 receptor-expressing medium spiny neurons of the nucleus accumbens guides inhibition-based choice behavior in mice.2023
- Author(s)
  Takatoshi Hikida, Tadaaki Nishioka, Suthinee Attachaipanich, Kosuke Hamaguchi, Michael Lazarus, Alban de Kerchove d'Exaerde, Tom Macpherson.
- Organizer
  62nd Annual Meeting of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] マウスにおける手がかりを用いた求餌行動時の内側前頭前皮質と側坐核の特異なドーパミン・ダイナミクスの観察2023
- Author(s)
  松本悠真、小澤貴明、尾山賀信、岩本涼太郎、Macpherson Tom、疋田貴俊
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] アルコール関連行動異常の根底にある核ー細胞質間輸送メカニズム2023
- Author(s)
  青峰良淳、櫻井航輝、マクファーソントム、小澤貴明、宮本洋一、米田悦啓、岡正啓、疋田貴俊
- Organizer
  第53回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Cell-type-specific control of reward and aversive signaling in the nucleus accumbens.2023
- Author(s)
  Macpherson T, Attachaipanich S, Nishioka T, Ozawa T, Hikida T
- Organizer
  日本生理学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Dopamine neurotransmission mechanisms in the nucleus accumbens for flexible cognitive behavior.2023
- Author(s)
  Hikida T, Nishioka T, Macpherson T, Hamaguchi K
- Organizer
  日本生理学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] 報酬予測中のマウスにおける線条体ドーパミン放出動態の学習依存的な変化2023
- Author(s)
  柴田智弘、小澤貴明、松本悠真、岩本涼太郎、尾山賀信、Macpherson Tom、疋田貴俊
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] アルコール関連行動異常を引き起こす核ー細胞質間輸送メカニズムの解析2023
- Author(s)
  青峰良淳、櫻井航輝、マクファーソントム、小澤貴明、宮本洋一、米田悦啓、岡正啓、疋田貴俊.
- Organizer
  第45回日本生物学的精神医学会年会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Importin α3 (Kpna3) deficiency induces sexually dimorphic aberrations in alcohol-related behaviors.2023
- Author(s)
  Yoshiatsu AOMINE, Koki SAKURAI, Tom MACPHERSON, Takaaki OZAWA, Yoichi MIYAMOTO, Yoshihiro YONEDA, Masahiro OKA, Takatoshi HIKIDA
- Organizer
  RIKEN International Symposium on Nuclear Structure and Function.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural mechanism of salt and umami seeking behavior2023
- Author(s)
  Ozawa T, Shibata T, Oyama Y, Abe M, Goto K, Yonemaru H, Matsumoto Y, Iwamoto R, Sakurai K, Macpherson T, Hikida T
- Organizer
  日本生理学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] インポーチンα3欠損マウスのアルコール関連行動およびその分子メカニズムの解析2023
- Author(s)
  青峰良淳、櫻井航輝、マクファーソントム、小澤貴明、宮本洋一、米田悦啓、岡正啓、疋田貴俊
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Dual roles for nucleus accumbens core dopamine D1-expressing neurons projecting to the substantia nigra pars reticulata in limbic and motor control.2023
- Author(s)
  Suthinee Attachaipanich, Takaaki Ozawa, Tom Macpherson, Takatoshi Hikida
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Cell-type-specific control of reward and aversive signaling in the Nucleus Accumbens2023
- Author(s)
  Tom Macpherson
- Organizer
  Physiological Society of Japan (PSJ) Meeting 2023
- Invited
- Data Source
  KAKENHI-PROJECT-21K15210
[Presentation] 恐怖条件づけ中のマウス前頭皮質・側坐核・扁桃体におけるドーパミン動態の解析2023
- Author(s)
  梅本和宏、小澤貴明、中村萌、岩本遼太郎、柴田智弘、尾山賀信、Tom Macpherson、疋田貴俊
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Pathway-specific roles of subthalamic nucleus projection neurons in motor and limbic functions.2023
- Author(s)
  Tianchang Zhao, Tadaaki Ozawa, Tom Macpherson, Takatoshi Hikida
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Analysis of dopamine dynamics in cortex, striatum, and amygdala during differential auditory fear conditioning in mice.2023
- Author(s)
  Takaaki Ozawa, Kazuhiro Umemoto, Moe Nakamura, Ryotaro Iwamoto, Yuma Matsumoto, Tomohiro Shibata, Yoshinobu Oyama, Tom Macpherson, Takatoshi Hikida.
- Organizer
  IRCN-iPlasticity International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Effects of Importin α1(KPNA1) depletion and adolescent social stress on psychiatric disorder-associated behaviors in mice.2022
- Author(s)
  Sakurai K, Kasahara E, Ozawa T, Macpherson T, Miyamoto Y, Yoneda Y, Sekiyama A, Oka M, Hikida T.
- Organizer
  Neuroscience 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural mechanisms in reward and aversion signaling2022
- Author(s)
  Tom Macpherson
- Organizer
  Japan Neuroscience Society (JNS) Meeting 2022
- Invited
- Data Source
  KAKENHI-PROJECT-21K15210
[Presentation] Analysis of dopamine release dynamics during temporal reward prediction.2022
- Author(s)
  Yuma Matsumoto, Tomohiro Shibata, Yoshinobu Oyama, Ryotaro Iwamoto, Tom Macpherson, Takatoshi Hikida, Takaaki Ozawa
- Organizer
  International Symposium on Chronogenesis: How the Mind Generates Time.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Striatal mechanisms of discrimination learning and their dysfunction in schizophrenia model mice.2022
- Author(s)
  Tom Macpherson
- Organizer
  Neuroscience 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Motivational increase and brain network variation based on functional connectivity in Importin α3 (KPNA3) deficient mice.2022
- Author(s)
  Aomine Y, Sakurai K, Macpherson T, Ozawa T, Miyamoto Y, Yoneda Y, Oka M, Hikida T
- Organizer
  Neuroscience 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural mechanisms in reward and aversion signaling2022
- Author(s)
  Tom Macpherson
- Organizer
  National Institute of Physiological Science (NIPS) Emotion Conference
- Invited
- Data Source
  KAKENHI-PROJECT-21K15210
[Presentation] Neural circuit mechanisms in behavioral flexibility2022
- Author(s)
  Tom Macpherson
- Organizer
  International Symposium on Artificial Intelligence and Brain Science 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural Mechanisms of Reward and Aversion Signaling2022
- Author(s)
  Tom Macpherson
- Organizer
  生理学研究所研究会2022『情動の本質を捉える最先端アプローチ』
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural mechanisms of reward and aversive signaling.2022
- Author(s)
  Tom Macpherson, Takatoshi Hikida
- Organizer
  Neuro2022
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] 恐怖条件づけ中のマウス脳内ドーパミン動態の解析2022
- Author(s)
  小澤貴明、中村萌、松本悠真、柴田智弘、岩本涼太郎、尾山賀信、Tom Macpherson、疋田貴俊.
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] 行動柔軟性における側坐核の並列神経回路機構2022
- Author(s)
  疋田貴俊、マクファーソントム.
- Organizer
  Neuro2022
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Striatal mechanisms of discrimination learning and their dysfunction in schizophrenia model mice2022
- Author(s)
  Tom Macpherson
- Organizer
  Society for Neuroscience (SfN) Meeting 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15210
[Presentation] Motivational increase and brain network variation based on functional connectivity in Importin α3 (KPNA3) deficient mice.2022
- Author(s)
  Hikida T, Aomine Y, Sakurai K, Macpherson T, Ozawa T, Miyamoto Y, Yoneda Y, Oka M.
- Organizer
  61st Annual Meeting of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Cell type-specific control of reward learning in the brain.2022
- Author(s)
  Tom Macpherson, Takatoshi Hikida
- Organizer
  The 17th International Symposium of the Institute Network for Biomedical Sciences.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] ネガティブな選択を回避する意思決定の神経機構2022
- Author(s)
  西岡忠昭、トムマクファーソン、濱口航介、疋田貴俊
- Organizer
  Neuro2022
- Invited
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Nucleus accumbens subpopulations cooperatively signal reward and aversion.2022
- Author(s)
  Tom Macpherson, Suthinee Attachaipanich, Tadaaki Nishioka, Takatoshi Hikida.
- Organizer
  4th Japan-UK Neuroscience Symposium 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural mechanisms for the strategy to avoid a choice that leads to negative outcome in visual discrimination learning.2022
- Author(s)
  Takatoshi Hikida, Tadaaki Nishioka, Tom Macpherson, Kosuke Hamaguchi
- Organizer
  4th International Touchscreen Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24205
[Presentation] Neural Mechanisms in Reward and Aversion2021
- Author(s)
  Tom Macpherson
- Organizer
  Osaka University Institute for Protein Research Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-21K15210
[Presentation] A role for Enkephalin-expressing ventral pallidal neurons in controlling aversive Pavlovian Conditioning2020
- Author(s)
  Macpherson Tom、Mizoguchi Hiroyuki 、Yamanaka Akihiro、Hikida Takatoshi
- Organizer
  第97回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex.2020
- Author(s)
  Tom Macpherson, Shuhei Yao, Ayumi Fukakusa, Makiko Morita, Haruhide Kimura, Keisuke Hirai, Tatsuya Ando, Hiroyoshi Toyoshiba, Akira Sawa, Takatoshi Hikida
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens D2-receptor-expressing neurons regulate reversal learning in the Attentional Set Shifting Test2020
- Author(s)
  Takatoshi Hikida, Jiyoon Kim, Tom Macpherson
- Organizer
  59th Annual Meeting of the American College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] A role for nucleus accumbens D1-/D2-neuron pathways in controlling learning impaired in psychiatric disorders2019
- Author(s)
  Macpherson Tom、Hikida Takatoshi
- Organizer
  第42回日本神経科学学会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T, Mizoguchi H, Yamanaka A, Hikida T.
- Organizer
  The 11th Meeting of the Federation of European Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T, Mizoguchi H, Yamanaka A, Hikida T.
- Organizer
  The 41th Annual Meeting of the Japan NeuroscienceSociety
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Enkephalin-Expressing Ventral Pallidal Neurons Control Aversive Learning.2018
- Author(s)
  Hikida T, Macpherson T, Mizoguchi H, Yamanaka A.
- Organizer
  57th Annual Meeting of the American College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T, Mizoguchi H, Yamanaka A, Hikida T.
- Organizer
  The 48th Annual Meeting of the Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens dopamine D1-receptor-expresing neurons control Pavlovian approach behaviour2017
- Author(s)
  Macpherson T, Hikida T
- Organizer
  The 44th Naito Conference, Decision Making in the Brain -Motivation, Prediction, and Learning
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens D1 receptor expressing neurons control sutoshaping behavior.2017
- Author(s)
  Macpherson T, Hikida T
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens dopamine D1-receptor-expresing neuron control of Pavlovian associative learning.2017
- Author(s)
  Macpherson T, Hikida T
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Dopamine D2L receptors control behavioral flexibility2017
- Author(s)
  Macpherson T, Hikida T
- Organizer
  OU-ANU 2nd joint symposium Protein Structure and Function
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens dopamine D1-receptor-expresing neurons control incentive salience to reward-predictive cues.2017
- Author(s)
  Macpherson T, Hikida T
- Organizer
  26th Annual Meeting of the International Behavioral Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens dopamine D1-receptor-expresing neurons control attribution of incentive salience in an autoshaping task.2017
- Author(s)
  Macpherson T, Hikida T
- Organizer
  EBPS Biennial meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] D2L receptor-expressing striatal neurons control visual discrimination learning in a touchscreen operant system.2017
- Author(s)
  Hikida T, Morita M, Macpherson T
- Organizer
  26th Annual Meeting of the International Behavioral Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Learning deficits involving nucleus accumbens D2-receptor expressing neurons in a DISC1 mouse model.2016
- Author(s)
  Morita M, Macpherson T, Sawa A, Hikida T
- Organizer
  Neuroscience 2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place learning task.2016
- Author(s)
  Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A, Hikida T
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Activity in dopamine D2-receptor-expressing nucleus accumbens is necessary for behavioral flexibility in an IntelliCage place discrimination task.2016
- Author(s)
  Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A, Hikida T
- Organizer
  Neuroscience 2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Activity in dopamine D2-receptor-expressing nucleus accumbens neurons is necessary for behavioral flexibility in an IntelliCage place discrimination task.2016
- Author(s)
  Tom Macpherson, Makiko Morita, Yanyan Wang, Toshikuni Sasaoka, Akira Sawa, Takatoshi Hikida
- Organizer
  日本生理学会第109回近畿生理学談話会
- Place of Presentation
  大阪市立大学医学研究科（大阪府・大阪市）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PLANNED-16H06568
[Presentation] Nucleus accumbens dopamine D2-receptor expressing neurons control behavioural flexibility in a place learning task in the IntelliCage.2016
- Author(s)
  Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A, Hikida T
- Organizer
  10th FENS Forum of Neuroscience
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06568

1. HIKIDA Takatoshi (70421378)

# of Collaborated Projects: 2 results

# of Collaborated Products: 59 results
2. 小澤貴明 (90625352)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
3. 山口隆司 (40724258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHUTO Takahide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. KUROIWA Mahomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 笹岡俊邦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 山中章弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 西昭徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 外角直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MACPHERSON TOM マクファーソン トム

Macpherson Tom マクファーソン トム

Research Projects

Research Products

Co-Researchers

戦略的な意思決定の神経機構と精神疾患病態の解明

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Research Institution

Investigation of nucleus accumbens subpopulations controlling reward and aversive learningPrincipal Investigator

Principal Investigator

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Research Institution

Neuronal circuit mechanisms of reward/goal-directed behavior

Principal Investigator

Project Period (FY)

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[Journal Article] Dual Roles for Nucleus Accumbens Core Dopamine D1-Expressing Neurons Projecting to the Substantia Nigra Pars Reticulata in Limbic and Motor Control in Male Mice2023

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[Journal Article] Editorial: Circuit, molecular, and developmental mechanisms in decision-making behavior2023

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[Journal Article] Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior in mice2023

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[Journal Article] Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice2023

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[Journal Article] Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice2022

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[Journal Article] Nucleus Accumbens Core Dopamine D2 Receptor-Expressing Neurons Control Reversal Learning but Not Set-Shifting in Behavioral Flexibility in Male Mice2022

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[Journal Article] Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex2020

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[Journal Article] Neurotransmission through dopamine D1 receptors is required for aversive memory formation and Arc activation in the cerebral cortex2020

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[Journal Article] Response to ‘Mood and Affect’2019

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[Journal Article] Role of basal ganglia neurocircuitry in the pathology of psychiatric disorders2019

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[Journal Article] Preproenkephalin-expressing ventral pallidal neurons control inhibitory avoidance learning. 2019 (in press)2019

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[Journal Article] Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice2019

Author(s)

MACPHERSON TOM マクファーソントム

Macpherson Tom マクファーソントム