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Terasaka Naohiro  寺坂 尚紘

ORCIDConnect your ORCID iD *help
Researcher Number 40830071
Other IDs
Affiliation (Current) 2025: 東京科学大学, 未来社会創成研究院, 特任准教授
Affiliation (based on the past Project Information) *help 2025: 東京科学大学, 未来社会創成研究院, 特任准教授
2023 – 2024: 東京工業大学, 地球生命研究所, 特任准教授
2022: 東京大学, 大学院理学系研究科(理学部), 助教
2019 – 2021: 東京大学, 大学院理学系研究科(理学部), 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 37030:Chemical biology-related / Transformative Research Areas, Section (III) / Medium-sized Section 28:Nano/micro science and related fields / Transformative Research Areas, Section (II) / Basic Section 45020:Evolutionary biology-related
Except Principal Investigator
Basic Section 28050:Nano/micro-systems-related / Transformative Research Areas, Section (III) / Medium-sized Section 38:Agricultural chemistry and related fields / Transformative Research Areas, Section (II)
Keywords
Principal Investigator
タンパク質工学 / 分子進化 / 合成生物学 / 無細胞翻訳系 / ハイスループットスクリーニング / バイオインフォマティクス / メタボロン / 分子進化工学 / 核酸工学 / DNAオリガミ … More / 自己集合タンパク質 / タンパク質 / マイクロデバイス / 非天然アミノ酸 / 蛋白質工学 / マイクロ流体デバイス / RNA ワールド / アミノアシル化 / RNAワールド / ペプチド / リボザイム … More
Except Principal Investigator
無細胞翻訳系 / マイクロ流路 / 液滴流路 / バイオセンサー / 生合成 / 天然物化学 / ウイルス模倣粒子 / 出芽酵母 / Casタンパク質 / CRISPR-Cas系 / メタゲノム / 耐熱性Casタンパク質 / 小型Casタンパク質 / ゲノム編集 / CRISPR-Cas / 分子進化 / 人工酵素 / 分子進化法 / タンパク質集合体 / タンパク質デザイン / タンパク質工学 Less
  • Research Projects

    (9 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (12 People)
  •  特化メタボロン・総括班

    • Principal Investigator
      森 貴裕
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  Development of artificial specialized metabolonPrincipal Investigator

    • Principal Investigator
      寺坂 尚紘
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Institute of Science Tokyo
  •  Development of a high-throughput directed evolution method for biosensors

    • Principal Investigator
      磯崎 瑛宏
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 28050:Nano/micro-systems-related
    • Research Institution
      Ritsumeikan University
  •  Development of cell-free evolution system to rapidly produce drug canditatesPrincipal Investigator

    • Principal Investigator
      寺坂 尚紘
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Institute of Science Tokyo
  •  独自に発見したCRISPR-Casエフェクターの機能構造解析と新たなゲノム編集技術の開発

    • Principal Investigator
      沼田 倫征
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      Kyushu University
  •  Construction of ribonucleoprotein nanoarchitecture in cellsPrincipal Investigator

    • Principal Investigator
      寺坂 尚紘
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 28:Nano/micro science and related fields
    • Research Institution
      Tokyo Institute of Technology
  •  Droplet-based microfluidics for directed evolution of higher-order protein assemblies containing noncanonical amino acidsPrincipal Investigator

    • Principal Investigator
      寺坂 尚紘
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Tokyo Institute of Technology
      The University of Tokyo
  •  Superior Protein Engineering by Evolution and Design

    • Principal Investigator
      鈴木 雄太
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Kyoto University
  •  In vitro evolution of a peptide-ribozyme complex catalyzing aminoacylationPrincipal Investigator

    • Principal Investigator
      Terasaka Naohiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 45020:Evolutionary biology-related
    • Research Institution
      The University of Tokyo

All 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch2020

    • Author(s)
      Ishida Satoshi、Terasaka Naohiro、Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Nature Chemical Biology

      Volume: 16 Issue: 6 Pages: 702-709

    • DOI

      10.1038/s41589-020-0500-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16200, KAKENHI-PROJECT-20H05618, KAKENHI-PLANNED-16H06444
  • [Presentation] Aminoacylation ribozymes evolved from a natural riboswitch2022

    • Author(s)
      Naohiro Terasaka
    • Organizer
      Symposium on Evolution and Emergence of Living Systems: from Geochemistry to Synthetic Biology(
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21H05116
  • [Presentation] 分子進化によるタンパク質・RNA 高次複合体の創成2022

    • Author(s)
      寺坂尚紘
    • Organizer
      第1回 発動分子科学サロン 「発動分子と生体材料」
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21H05116
  • [Presentation] 原始ウイルスの進化を実験室内で再現する2022

    • Author(s)
      寺坂尚紘
    • Organizer
      日本進化学会年大会 第24回沼津大会
    • Data Source
      KAKENHI-ORGANIZER-21H05116
  • [Presentation] 実験室内進化によるウイルス模倣粒子の創成2022

    • Author(s)
      寺坂尚紘
    • Organizer
      第47回 生命の起原および進化学会学術講演会
    • Data Source
      KAKENHI-ORGANIZER-21H05116
  • [Presentation] 分子進化によるタンパク質集合体の構築2022

    • Author(s)
      寺坂尚紘
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-ORGANIZER-21H05116
  • [Presentation] An aminoacylation ribozyme evolved from a natural tRNA sensing riboswitch2020

    • Author(s)
      寺坂尚紘、石田啓、加藤敬行、菅 裕明
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K16200
  • [Presentation] 天然リボスイッチ配列から進化させ、翻訳系中で働くアミノア シル tRNA合成リボザイム2019

    • Author(s)
      寺坂 尚紘, 石田啓, 加藤敬行, 菅裕明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K16200
  • [Presentation] T-box リボスイッチをベースにした tRNA 認識アミノアシル化リボザイムの創出2019

    • Author(s)
      石田啓, 寺坂 尚紘, 加藤敬行, 菅裕明
    • Organizer
      第21回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-19K16200
  • [Presentation] An aminoacylation ribozyme evolved from a natural tRNA sensing riboswitch2019

    • Author(s)
      Terasaka Naohiro、Ishida Satoshi、Katoh Takayuki、Suga Hiroaki
    • Organizer
      The 24th Annual Meeting of the RNA Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16200
  • 1.  古林 太郎 (20902620)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  鈴木 雄太 (00827743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  岡本 泰典 (50843405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  沼田 倫征 (10401564)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  岡田 悟 (30734488)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  酒井 雄介 (10895501)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  森 貴裕 (60734564)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  佐々木 栄太 (00803157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  和氣 駿之 (10793705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  中野 祥吾 (80748541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  磯崎 瑛宏 (10732555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  那須 雄介 (60831328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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