Yamaguchi Yohei 山口陽平

Researcher Number	40831912
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 名古屋市立大学, 医薬学総合研究院(医学), 助教 2019 – 2023: 旭川医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Basic Section 90110:Biomedical engineering-related Except Principal Investigator Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator 心筋細胞 / メカノバイオロジー / 機械受容チャネル / 血圧 / 静水圧負荷 / 静水圧 / メカニカルストレス / TRPチャネル / バイオメカニクス / TRPC … More / 亜鉛 / TRPCチャネル / フランク・スターリング機構 / 圧力刺激 / 眼内平滑筋 / カルシウムハンドリング / 静水圧刺激 / 毛様体筋細胞 / 筋細胞 … More Except Principal Investigator 細胞死 / 心筋細胞 / メカノバイオロジー / ミトコンドリア膜電位 / 心筋力学 / メカノトランスダクション / 酸化ストレス / 機械的負荷 / 活性酸素 / 機械感受性 Less

隣接細胞における心筋死細胞認識シグナルの解明
- Principal Investigator
  
  金子智之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Asahikawa Medical College
Analyses of the interaction between blood pressure-derived mechano-stress and cardiomyocyte dynamics.Principal Investigator
- Principal Investigator
  
  山口陽平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Nagoya City University
The Role of ROS Signaling in Regulating Myocardial Mechanosensitive Responses and Its Application to Heart Failure Therapy
- Principal Investigator
  
  Iribe Gentaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Asahikawa Medical College
Elucidation of the regulation mechanism of cardiac biomechanics by focusing on TRPC channelsPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yohei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Nagoya City University
  Asahikawa Medical College
Analysis of interaction between intraocular pressure-derived mechano-stress and internal calcium kinetics in ciliary musclesPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yohei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Asahikawa Medical College

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Effect of High Hydrostatic Pressure on Cardiomyocytes2023
- Author(s)
  YAMAGUCHI Yohei、MORIMATSU Masatoshi
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 63 Issue: 5 Pages: 261-262
- DOI
  10.2142/biophys.63.261
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11800, KAKENHI-PROJECT-21K15338
[Journal Article] 高圧力顕微鏡による心筋細胞の収縮イメージング2023
- Author(s)
  西山雅祥，山口陽平，金子智之，森松賢順
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 1134-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15338
[Journal Article] Afterコロナ，After北海道2023
- Author(s)
  山口陽平
- Journal Title
  
  日本生理学会雑誌
  
  Volume: 85 Pages: 64-65
- Data Source
  KAKENHI-PROJECT-21K15338
[Journal Article] 高圧力顕微鏡による心筋細胞の収縮イメージング2023
- Author(s)
  西山雅祥，山口陽平，金子智之，森松賢順
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 1134-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11800
[Journal Article] Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through beta-adrenoreceptors.2022
- Author(s)
  Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, Kato Y, Numaga-Tomita T, Kaneko T, Mangmool S, Kuroda T, Okubo R, Sanbo M, Hirabayashi M, Sato Y, Nakagawa Y, Kuwahara K, Nagata R, Iribe G, mori Y, Nishida M.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Issue: 1 Pages: 6374-6374
- DOI
  10.1038/s41467-022-34194-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08099, KAKENHI-PROJECT-22K12900, KAKENHI-PROJECT-22K19395, KAKENHI-PROJECT-21K15338, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20H03673, KAKENHI-PUBLICLY-22H04814, KAKENHI-PROJECT-23K24035, KAKENHI-PROJECT-23K24078
[Journal Article] High hydrostatic pressure induces slow contraction in mouse cardiomyocytes2022
- Author(s)
  Yamaguchi Yohei、Nishiyama Masayoshi、Kai Hiroaki、Kaneko Toshiyuki、Kaihara Keiko、Iribe Gentaro、Takai Akira、Naruse Keiji、Morimatsu Masatoshi
- Journal Title
  
  Biophysical Journal
  
  Volume: 121 Issue: 17 Pages: 3286-3294
- DOI
  10.1016/j.bpj.2022.07.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12598, KAKENHI-PROJECT-21K12645, KAKENHI-PROJECT-21K15338, KAKENHI-PUBLICLY-22H05697, KAKENHI-PLANNED-21H05128, KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-23K23190
[Journal Article] Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells2021
- Author(s)
  Yamaguchi Yohei、Allegrini Benoit、Rapetti-Mauss Raphael、Picard Veronique、Garcon Loic、Kohl Peter、Soriani Olivier、Peyronnet Remi、Guizouarn Helene
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 12
- DOI
  10.3389/fphys.2021.736585
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16485, KAKENHI-PROJECT-21K15338
[Presentation] 心筋細胞の収縮能への高静水圧負荷の影響2024
- Author(s)
  山口陽平，金子智之，張夏智，村田影星，入部玄太郎，西山雅祥，大矢進
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K11800
[Presentation] TRPC6 modulates Zinc mobilization to regulate stretch-induced increases in myocardial contractility2024
- Author(s)
  Yohei Yamaguchi, Toshiyuki Kaneko, Keiji Naruse, Gentaro Iribe, Susumu Ohya
- Organizer
  The 2024 Biophysical Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] TRPC6 modulates Zinc mobilization to regulate stretch-induced increase in myocardial contractility2024
- Author(s)
  Yohei Yamaguchi, Toshiyuki Kaneko, Keiji Naruse, Gentaro Iribe, Susumu Ohya
- Organizer
  The 2024 Biophysical Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11800
[Presentation] マウス心筋細胞におけるTRPC6による力学特性の制御機構2023
- Author(s)
  山口陽平，金子智之，成瀬恵治，大矢進，入部玄太郎
- Organizer
  第17回トランスポーター研究会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] マウス心筋のTRPC6によるZn2+を介した伸展誘発性収縮力増加反応の制御2023
- Author(s)
  山口陽平，金子智之，入部玄太郎，大矢進
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] マウス心筋細胞の力学特性に対するTRPC6ノックアウトの影響2023
- Author(s)
  山口陽平，金子智之，成瀬恵治，大矢進，入部玄太郎
- Organizer
  生理学研究所研究会「TRP研究会2023」
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] Suppression of TRPC6 augments Frank-Starling mechanism in mouse cardiomyocyte2023
- Author(s)
  Yohei Yamaguchi, Kaneko Toshiyuki, Iribe Gentaro
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 心筋細胞における生理的レベルの圧負荷のカルシウムハンドリングへの影響2023
- Author(s)
  山口陽平，金子智之，大矢進，西山雅祥
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K11800
[Presentation] マウス心筋細胞で認める高静水圧誘発性緩徐収縮2022
- Author(s)
  Yohei Yamaguchi, Masayoshi Nishiyama, Hiroaki Kai, Toshiyuki Kaneko, Keiko Kaihara, Gentaro Iribe, Akira Takai, Keiji Naruse, Masatoshi Morimatsu
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] マウス心筋細胞における伸展誘発性張力変化現象におけるTRPC6の役割2022
- Author(s)
  山口陽平, 金子智之, 入部玄太郎
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 高静水圧で誘発される心筋細胞の緩徐な収縮現象2022
- Author(s)
  山口陽平, 西山雅祥, 甲斐廣彬, 金子智之, 入部玄太郎, 成瀬恵治, 森松賢順
- Organizer
  生体運動研究合同班会議2022
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 高静水圧で誘発されるマウス心筋細胞の緩徐な収縮現象2022
- Author(s)
  山口陽平, 西山雅祥, 甲斐寛彬, 金子智之, 貝原恵子, 入部玄太郎, 高井章, 成瀬恵治, 森松賢順
- Organizer
  第102回日本生理学会北海道地方会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 高静水圧で誘発される心筋細胞の緩徐な収縮現象2022
- Author(s)
  山口陽平、西山雅祥、甲斐廣彬、金子智之、入部玄太郎、成瀬恵治、森松賢順
- Organizer
  生体運動研究合同班会議2022
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] マウス心筋細胞における伸展誘発性張力変化現象におけるTRPC6の役割2022
- Author(s)
  山口陽平、金子智之、入部玄太郎
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] Potential role of TRPC6 channels on single cell mechanics in mouse cardiomyocytes2022
- Author(s)
  Yohei Yamaguchi, Toshiyuki Kaneko, Keiji Naruse, Gentaro Iribe
- Organizer
  9th World Congress of Biomechanics 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 高圧力により誘発される心筋細胞の非典型的収縮2021
- Author(s)
  山口陽平, 西山雅祥, 金子智之, 入部玄太郎, 成瀬恵治, 森松賢順
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 高圧力下で誘起される心筋細胞の収縮運動2021
- Author(s)
  山口陽平, 西山雅祥, 金子智之, 入部玄太郎, 成瀬恵治, 森松賢順
- Organizer
  第62回高圧討論会
- Data Source
  KAKENHI-PROJECT-21K15338
[Presentation] 細胞内カルシウム濃度変化非依存的に生じるマウス心筋細胞の圧誘発性収縮2021
- Author(s)
  山口陽平，西山雅祥，入部玄太郎，森松賢順
- Organizer
  第5回日本メカノバイオロジー学会学術大会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] 高圧力下で誘起される心筋細胞の収縮運動2021
- Author(s)
  山口陽平、西山雅祥、金子智之、入部玄太郎、成瀬恵治、森松賢順
- Organizer
  第62回高圧討論会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] 心筋の力学現象におけるTRPCチャネル複合体の生理機能2021
- Author(s)
  山口陽平、成瀬恵治、入部玄太郎
- Organizer
  第126回日本解剖学会総会・全国学術集会／第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] 高圧力により誘発される心筋細胞の非典型的収縮2021
- Author(s)
  山口陽平、西山雅祥、金子智之、入部玄太郎、成瀬恵治、森松賢順
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] Intracellular Calcium Concentration-independent Cardiomyocyte Contraction Triggered by High Hydrostatic Pressure2021
- Author(s)
  Yohei Yamaguchi, Masayoshi Nishiyama, Gentaro Iribe, Keiji Naruse, Masatoshi Morimatsu
- Organizer
  65th Annual Meeting Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] High Hydrostatic Pressure induces Cardiomyocyte Contraction2020
- Author(s)
  Yohei Yamaguchi, Masayoshi Nishiyama, Hiroaki Kai, Gentaro Iribe, Keiji Naruse, Masatoshi Morimatsu
- Organizer
  第59回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] The role of TRPC3 and TRPC6 in a stretch-induced slow force response in cardiomyocytes2020
- Author(s)
  山口陽平、入部玄太郎、成瀬恵治、高井章
- Organizer
  第97回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] 心筋細胞のバイオメカニクス制御におけるTRPC6の役割2020
- Author(s)
  山口陽平、高井章、入部玄太郎
- Organizer
  2019年度日本生物物理北海道支部会例会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] Role of TRPC6 on single cell mechanics in mouse cardiomyocytes2020
- Author(s)
  Yohei Yamaguchi, Gentaro Iribe, Keiji Naruse, Akira Takai
- Organizer
  64th Annual Meeting Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] 細胞内カルシウム濃度変化非依存的に生じる心筋細胞の圧誘発性収縮2020
- Author(s)
  山口陽平，西山雅祥，入部玄太郎，森松賢順
- Organizer
  第100回北海道医学大会生理系分科会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] Role of TRPC channels on single cell mechanics in mouse cardiomyocyte2020
- Author(s)
  山口陽平、入部玄太郎、成瀬恵治、高井章
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K16485
[Presentation] 心筋細胞のマイクロバイオメカニクスにおけるTRPC6の役割2019
- Author(s)
  山口陽平、入部玄太郎、高井章
- Organizer
  2019年度日本生理学会北海道地方会
- Data Source
  KAKENHI-PROJECT-19K16485

1. 金子智之 (80638643)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. Iribe Gentaro (90284885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 貝原恵子 (60638641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 千葉弓子 (70835777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAGAWA Yasuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 錦見俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 桑原宏一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 成瀬恵治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaguchi Yohei 山口 陽平

Research Projects

Research Products

Co-Researchers

隣接細胞における心筋死細胞認識シグナルの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of the interaction between blood pressure-derived mechano-stress and cardiomyocyte dynamics.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Role of ROS Signaling in Regulating Myocardial Mechanosensitive Responses and Its Application to Heart Failure Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the regulation mechanism of cardiac biomechanics by focusing on TRPC channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of interaction between intraocular pressure-derived mechano-stress and internal calcium kinetics in ciliary musclesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Effect of High Hydrostatic Pressure on Cardiomyocytes2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] 高圧力顕微鏡による心筋細胞の収縮イメージング2023

Author(s)

Journal Title

Data Source

[Journal Article] Afterコロナ，After北海道2023

Author(s)

Journal Title

Data Source

[Journal Article] 高圧力顕微鏡による心筋細胞の収縮イメージング2023

Author(s)

Journal Title

Data Source

[Journal Article] Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through beta-adrenoreceptors.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High hydrostatic pressure induces slow contraction in mouse cardiomyocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 心筋細胞の収縮能への高静水圧負荷の影響2024

Author(s)

Organizer

Data Source

[Presentation] TRPC6 modulates Zinc mobilization to regulate stretch-induced increases in myocardial contractility2024

Author(s)

Organizer

Data Source

[Presentation] TRPC6 modulates Zinc mobilization to regulate stretch-induced increase in myocardial contractility2024

Author(s)

Organizer

Data Source

Yamaguchi Yohei 山口陽平