Parrish Nicholas ＰａｒｒｉｓｈＮｉｃｈｏｌａｓ

Researcher Number	40833851
Other IDs
Affiliation (Current)	2026: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員主管研究員
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員主管研究員 2020 – 2023: 国立研究開発法人理化学研究所, 生命医科学研究センター, 理研白眉研究チームリーダー
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related Except Principal Investigator Broad Section F
Keywords	Principal Investigator 潜伏感染 / テロメア / 抗ウイルス免疫 / 内在性ウイルス様エレメント / ヘルペスウイルス / 大規模解析 / 再活性化 / ヒトゲノム / ヒトヘルペスウイルス6 / 内在性ウイルス … More / WGS / Disease association / Endogenous virus / HHV-6 … More Except Principal Investigator 抗ウイルス作用 / 内在性RNAウイルス / ウイルス免疫 / ゲノム多様性 / 共進化 / ゲノム免疫 / ボルナウイルス / 内在性ウイルス Less

ヘルペスウイルスのゲノムへの組み込みと再活性化: 大規模解析から探る疾患との関連Principal Investigator
- Principal Investigator
  
  Parrish Nicholas
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Institute of Physical and Chemical Research
Genome immunity: elucidation of the antiviral activity of endogenous bornaviruses and their utilization as functional resources
- Principal Investigator
  
  Tomonaga Keizo
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section F
- Research Institution
  Kyoto University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection2025
- Author(s)
  Rie Koide, Takaya Abe, Taichi Harimoto, Anselmo Jiro Kamada, Yuka Saito, Matteo Guerrini, Asami Fujii, Erica Parrish, Masayuki Horie, Hiroshi Kiyonari, Kazuhiko Yamamoto, Keizo Tomonaga, Nicholas F Parrish
- Journal Title
  
  PLoS Pathogens
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05682
[Journal Article] Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk2023
- Author(s)
  6.Kojima S, Koyama S, Ka M, Saito Y, Parrish EH, Endo M, Takata S, Mizukoshi M, Hikino K, Takeda A, Gelinas AF, HeatonSM, Koide R, Kamada AJ, Noguchi M, Hamada M; Biobank Japan Project Consortium; Kamatani Y, Murakawa Y, Ishigaki K,Nakamura Y, Ito K, Terao C, Momozawa Y, Parrish NF
- Journal Title
  
  Nature Genetics
  
  Volume: 55 Issue: 6 Pages: 939-951
- DOI
  10.1038/s41588-023-01390-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0209, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22K15385, KAKENHI-PROJECT-20H05682, KAKENHI-PROJECT-23K24373
[Journal Article] Mammalian antiviral systems directed by small RNA2021
- Author(s)
  Takahashi Tomoko、Heaton Steven M.、Parrish Nicholas F.
- Journal Title
  
  PLOS Pathogens
  
  Volume: 17 Issue: 12 Pages: e1010091-e1010091
- DOI
  10.1371/journal.ppat.1010091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05682
[Journal Article] Virus-derived variation in diverse human genomes2021
- Author(s)
  Kojima Shohei、Kamada Anselmo Jiro、Parrish Nicholas F.
- Journal Title
  
  PLOS Genetics
  
  Volume: 17 Issue: 4 Pages: e1009324-e1009324
- DOI
  10.1371/journal.pgen.1009324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21442
[Journal Article] Virus-like insertions with sequence signatures similar to those of endogenous non-retroviral RNA viruses in the human genome.2021
- Author(s)
  Kojima S, Yoshikawa K, Ito J, Nakagawa S, Parrish NF, Horie M, Kawano S, Tomonaga K.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 118 Issue: 5
- DOI
  10.1073/pnas.2010758118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PLANNED-16H06430, KAKENHI-PUBLICLY-19H04843, KAKENHI-PROJECT-20H05682, KAKENHI-PROJECT-20H00662, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04833, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-20K15767
[Presentation] Inherited Chromosomally-Integrated or Endogenous human herpesvirus 6 as a disease risk factor2025
- Author(s)
  Nicholas Parrish, Shohei Kojima, Rie Koide, Noah Sasa, Alexander Bick
- Organizer
  12th International Conference on HHV-6 & 7
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] Role of immune response against endogenous human herpesvirus 6 in autoimmunity2025
- Author(s)
  Rie Koide, Shohei Kojima, Noah Sasa, Yukinori Okada, Nicholas Parrish
- Organizer
  12th International Conference on HHV-6 & 7
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] Immune response to endogenous human herpesvirus 6 in autoimmune disease patients2024
- Author(s)
  小出りえ、小嶋将平、佐々暢亜、岡田随象、ニコラス・パリッシュ
- Organizer
  第26回日本進化学会神奈川大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] 内在性ヒトヘルペスウイルス6に対する自己免疫応答の評価2024
- Author(s)
  小出りえ、小嶋将平、佐々暢亜、岡田随象、ニコラス・パリッシュ
- Organizer
  第71回日本ウイルス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] Potential involvement of endogenous HHV-6 in lymphangioleiomyomatosis2022
- Author(s)
  Hayakawa K, Kojima S, Parrish NF.
- Organizer
  45th Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] Viruses make us who we are2022
- Author(s)
  Parrish NF.
- Organizer
  Vanderbilt University Medical Center Section of Surgical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] Screening for human herpesvirus 6 integrated in human genomes using biobank- scale sequencing data.2021
- Author(s)
  Kojima, S., Parrish, N.F.
- Organizer
  68th Japan Society for Virology annual meeting.
- Data Source
  KAKENHI-PROJECT-23K21442
[Presentation] A mouse model to test for EVE-derived antiviral activity against Borna disease virus.2021
- Author(s)
  Koide R, Abe T, Kamada AJ, Saito Y, Guerrini M, Fujii A, Parrish EH, Horie M, Kiyonari H, Koyasu S, Yamamoto K, Tomonaga K, Parrish NF.
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20H05682

1. Tomonaga Keizo (10301920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 村川泰裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Parrish Nicholas Ｐａｒｒｉｓｈ Ｎｉｃｈｏｌａｓ

Research Projects

Research Products

Co-Researchers

ヘルペスウイルスのゲノムへの組み込みと再活性化: 大規模解析から探る疾患との関連Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome immunity: elucidation of the antiviral activity of endogenous bornaviruses and their utilization as functional resources

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection2025

Author(s)

Journal Title

Data Source

[Journal Article] Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mammalian antiviral systems directed by small RNA2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Virus-derived variation in diverse human genomes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Virus-like insertions with sequence signatures similar to those of endogenous non-retroviral RNA viruses in the human genome.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Inherited Chromosomally-Integrated or Endogenous human herpesvirus 6 as a disease risk factor2025

Author(s)

Organizer

Data Source

[Presentation] Role of immune response against endogenous human herpesvirus 6 in autoimmunity2025

Author(s)

Organizer

Data Source

[Presentation] Immune response to endogenous human herpesvirus 6 in autoimmune disease patients2024

Author(s)

Organizer

Data Source

[Presentation] 内在性ヒトヘルペスウイルス6に対する自己免疫応答の評価2024

Author(s)

Organizer

Data Source

[Presentation] Potential involvement of endogenous HHV-6 in lymphangioleiomyomatosis2022

Author(s)

Organizer

Data Source

[Presentation] Viruses make us who we are2022

Author(s)

Organizer

Data Source

[Presentation] Screening for human herpesvirus 6 integrated in human genomes using biobank- scale sequencing data.2021

Author(s)

Organizer

Data Source

[Presentation] A mouse model to test for EVE-derived antiviral activity against Borna disease virus.2021

Author(s)

Organizer

Data Source

Parrish Nicholas ＰａｒｒｉｓｈＮｉｃｈｏｌａｓ