Kurosawa Ryo 黒澤亮

Researcher Number	40836384
Other IDs
Affiliation (Current)	2025: 東北大学, 東北メディカル・メガバンク機構, 助教 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員研究員
Affiliation (based on the past Project Information) *help	2025: 東北大学, 東北メディカル・メガバンク機構, 助教 2022 – 2023: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2022: 東北大学, 医学系研究科, JSPS特別研究員(PD) 2020 – 2021: 東北大学, 医学系研究科, 大学院非常勤講師 2019: 東北大学, 医学系研究科, JSPS特別研究員(PD) 2019: 東北大学, 東北メディカル・メガバンク機構, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator ゲノムワイド関連解析 / 弁膜症 / 冠攣縮性狭心症 / 肺動脈平滑筋細胞 / セラストラマイシン / 化合物スクリーニング / 肺動脈性肺高血圧症 Except Principal Investigator 肺高血圧症 / 肺動脈性肺高血圧症 / 肺高血圧

弁膜症とそのサブタイプに対する世界初のゲノムワイド関連解析による遺伝的基盤の解明Principal Investigator
- Principal Investigator
  
  黒澤亮
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tohoku University
冠攣縮性狭心症に対する世界初のゲノムワイド関連解析による遺伝要因の同定Principal Investigator
- Principal Investigator
  
  黒澤亮
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Institute of Physical and Chemical Research
Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension High-Throughput Screening of 5562 Compounds.Principal Investigator
- Principal Investigator
  
  Kurosawa Ryo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tohoku University
Extraction of Pulmonary Hypertension Pathogenic Proteins and Development of Therapeutic Methods for Achieving Next-Generation Preventive Medicine
- Principal Investigator
  
  Satoh Kimio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tohoku University

All 2021 2020 2019

All Journal Article Presentation Book

[Book] 肺高血圧症とPRO2020
- Author(s)
  黒澤亮、佐藤公雄、下川宏明
- Total Pages
  72
- Publisher
  メディカルレビュー社
- ISBN
  9784779225109
- Data Source
  KAKENHI-PROJECT-19K17549
[Journal Article] Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A)2021
- Author(s)
  Kurosawa R, Satoh K, Nakata T, Shindo T, Kikuchi N, Satoh T, Siddique MAH, Omura J, Sunamura S, Nogi M, Takeuchi Y, Miyata S, Shimokawa H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 41 Issue: 3 Pages: 1205
- DOI
  10.1161/atvbaha.120.315731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-21K19469
[Journal Article] Identification of the novel variants in patients with chronic thromboembolic pulmonary hypertension2020
- Author(s)
  Yaoita N, Satoh K, Tatebe S, Yasuda S, Shimokawa H et al.
- Journal Title
  
  J Am Heart Assoc .
  
  Volume: 9 Issue: 21 Pages: 1-12
- DOI
  10.1161/jaha.120.015902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08531, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-21K19469
[Journal Article] Checkpoint kinase 1 promotes the development of pulmonary arterial hypertension2019
- Author(s)
  Satoh K, Kikuchi N, Kurosawa R, Shimokawa H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 39 Issue: 8 Pages: 1504-1506
- DOI
  10.1161/atvbaha.119.312969
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647
[Journal Article] Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension: Novel Effects of an Old Drug2019
- Author(s)
  Siddique MAH, Satoh K, Kurosawa R, Kikuchi N, Elias-Al-Mamun M, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Ueda H, Tokuyama H, Shimokawa H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 39 Issue: 11 Pages: 2367
- DOI
  10.1161/atvbaha.119.313309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11847, KAKENHI-PUBLICLY-18H04231, KAKENHI-PUBLICLY-18H04379, KAKENHI-PUBLICLY-18H04642, KAKENHI-PROJECT-18H02549, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-17K08204
[Journal Article] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension: class FormattedString { value: High-Throughput Screening of 5562 Compounds }2019
- Author(s)
  Kurosawa R, Satoh K, Kikuchi N, Kikuchi H, Saigusa D, Elias-Al-Mamun M, Siddique MAH, Omura J, Satoh T, Sunamura S, Nogi M, Numano K, Miyata S, Uruno A, Kano K, Matsumoto Y, Doi T, Aoki J, Oshima Y, Yamamoto M, Shimokawa H
- Journal Title
  
  Circ Res
  
  Volume: 125 Issue: 3 Pages: 309
- DOI
  10.1161/circresaha.119.315229
- URL
  https://localhost/en/publications/3bf98e64-b6ae-4674-853e-45a8a1820fca
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19K17549, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-16KK0195
[Journal Article] Identification of Adipsin as a Novel Prognostic Biomarker in Patients With Coronary Artery Disease2019
- Author(s)
  Ohtsuki T, Satoh K, Shimizu T, Ikeda S, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Sunamura S, Yaoita N, Omura J, Aoki T, Tatebe S, Sugimura K, Takahashi J, Miyata S, Shimokawa H.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 8 Issue: 23
- DOI
  10.1161/jaha.119.013716
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647
[Journal Article] ADAMTS8 promotes the development of pulmonary arterial hypertension and right ventricular failure a possible novel therapeutic target2019
- Author(s)
  Omura J, Satoh K, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Ohtsuki T, Elias-Al-Mamun M, Siddique MAH, Yaoita N, Sunamura S, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H
- Journal Title
  
  Circ Res
  
  Volume: 125 Issue: 10 Pages: 884
- DOI
  10.1161/circresaha.119.315398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647
[Journal Article] Diagnostic and Prognostic Significance of Serum Levels of SeP (Selenoprotein P) in Patients with Pulmonary Hypertension2019
- Author(s)
  Nobuhiro Kikuchi, Kimio Satoh, Taijyu Satoh, Nobuhiro Yaoita, Mohammad Abdul Hai Siddique, Junichi Omura, Ryo Kurosawa, Masamichi Nogi, Shinichiro Sunamura, Satoshi Miyata, Hirofumi Misu, Yoshiro Saito, Hiroaki Shimokawa
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 39 Issue: 12 Pages: 2553
- DOI
  10.1161/atvbaha.119.313267
- URL
  https://localhost/en/publications/be0d8f72-5974-4474-907e-2c1b5325427e
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-19K22480, KAKENHI-PROJECT-17H03821
[Presentation] スクリーニングによる新規肺高血圧症治療薬Celastramycinの発見2020
- Author(s)
  黒澤亮、佐藤公雄、菊地順裕、佐藤大樹、Mohammad A. H. Siddique、大村淳一、砂村慎一郎、野木正道、下川宏明
- Organizer
  第5回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17549
[Presentation] 化合物スクリーニングによる新規肺高血圧症治療薬の発見2020
- Author(s)
  黒澤亮, 佐藤公雄, 菊地順裕, 大村淳一, 佐藤大樹, M. A. H. Siddique, Md. E. A. Mamun, 砂村慎一郎, 野木正道, 下川宏明
- Organizer
  第84回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17549
[Presentation] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds-2019
- Author(s)
  Ryo Kurosawa, Kimio Satoh, Nobuhiro Kikuchi, Taijyu Satoh, Junichi Omura, Masamichi Nogi, Shinichiro Sunamura, Nobuhiro Yaoita, Mohammad Abdul Hai Siddique, Elias Al-Mamun, Toru Shimizu, Hiroaki Shimokawa
- Organizer
  欧州心臓病学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17549
[Presentation] スクリーニングによる新規肺高血圧症治療薬Celastramycinの発見2019
- Author(s)
  黒澤亮、佐藤公雄、菊地順裕、大村淳一、佐藤大樹、Mohammad Abdul Hai Siddique、Md. Elias Al-Mamun、砂村慎一郎、野木正道、下川宏明
- Organizer
  第４回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17549
[Presentation] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds.2019
- Author(s)
  Kurosawa R, Satoh K, et al.
- Organizer
  American Heart Association (AHA) Scientific Sessions (Philadelphia, Pennsylvania , USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03647
[Presentation] Identification of celastramycin as a novel therapeutic agent for pulmonary arterial hypertension -high-throughput screening of 5,562 compounds.2019
- Author(s)
  Kurosawa R, Satoh K, et al.
- Organizer
  ESC Congress 2019 (Paris, France)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03647
[Presentation] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds-2019
- Author(s)
  Ryo Kurosawa, Kimio Satoh, Nobuhiro Kikuchi, Taijyu Satoh, Junichi Omura, Masamichi Nogi, Shinichiro Sunamura, Nobuhiro Yaoita, Mohammad Abdul Hai Siddique, Elias Al-Mamun, Toru Shimizu, Hiroaki Shimokawa
- Organizer
  米国心臓協会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17549

1. Satoh Kimio (80436120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 宮田敏 (60360343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 菊地順裕 (70816454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 伊藤薫 (50375664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kurosawa Ryo 黒澤 亮

Research Projects

Research Products

Co-Researchers

弁膜症とそのサブタイプに対する世界初のゲノムワイド関連解析による遺伝的基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

冠攣縮性狭心症に対する世界初のゲノムワイド関連解析による遺伝要因の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension High-Throughput Screening of 5562 Compounds.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Extraction of Pulmonary Hypertension Pathogenic Proteins and Development of Therapeutic Methods for Achieving Next-Generation Preventive Medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 肺高血圧症とPRO2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of the novel variants in patients with chronic thromboembolic pulmonary hypertension2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Checkpoint kinase 1 promotes the development of pulmonary arterial hypertension2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension: Novel Effects of an Old Drug2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension: class FormattedString { value: High-Throughput Screening of 5562 Compounds }2019

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Journal Article] Identification of Adipsin as a Novel Prognostic Biomarker in Patients With Coronary Artery Disease2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAMTS8 promotes the development of pulmonary arterial hypertension and right ventricular failure a possible novel therapeutic target2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnostic and Prognostic Significance of Serum Levels of SeP (Selenoprotein P) in Patients with Pulmonary Hypertension2019

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Presentation] スクリーニングによる新規肺高血圧症治療薬Celastramycinの発見2020

Author(s)

Kurosawa Ryo 黒澤亮