Fujiwara Takayuki 藤原隆行

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Takayuki Fujiwara 藤原隆行

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Researcher Number	40836441
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 特任助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 特任助教 2020 – 2023: 東京大学, 医学部附属病院, 特任助教 2019: 東京大学, 医学部附属病院, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 肺動脈性肺高血圧症 / 肺高血圧症 / シングルセルRNA解析 / 組織透明化技術 / 血管新生 / 大動脈瘤症候群 / 組織透明化 / 家族性大動脈瘤/解離 / 血管平滑筋細胞 / 血管内皮細胞 … More / DNA損傷 / 三次元可視化 / 多光子励起顕微鏡 / 多光子顕微鏡 … More Except Principal Investigator 空間的発現解析 / シングルセル解析 / モデルマウス / 肺動脈性肺高血圧症 Less

肺細動脈内皮細胞の機能変容に焦点を当てた新規肺高血圧モデルの病態解明と治療法開発
- Principal Investigator
  
  武田憲文
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
三次元可視化システムによる難治性血管疾患の病態解明Principal Investigator
- Principal Investigator
  
  藤原隆行
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
Investigation of pathophysiology of hereditary pulmonary hypertension using novel 3D imaging systemPrincipal Investigator
- Principal Investigator
  
  Fujiwara Takayuki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Three-dimensional pathophysiological analysis of pulmonary hypertension using tissue-clearing method and mutiphoton microscopyPrincipal Investigator
- Principal Investigator
  
  Takayuki Fujiwara
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] The ratio of TAPSE to PASP predicts prognosis in lung transplant candidates with pulmonary arterial hypertension2023
- Author(s)
  Ishii, S. Minatsuki, S. Hatano, M. Saito, A. Yagi, H. Shimbo, M. Soma, K. Fujiwara, T. Itoh, H. Konoeda, C. Sato, M. Takeda, N. Daimon, M. Nakajima, J. Komuro, I.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 3758-3758
- DOI
  10.1038/s41598-023-30924-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08276, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-20K08398
[Journal Article] Prognostic value of follow-up vasoreactivity test in pulmonary arterial hypertension2023
- Author(s)
  Ishii, S. Hatano, M. Maki, H. Minatsuki, S. Saito, A. Yagi, H. Shimbo, M. Soma, K. Numata, G. Fujiwara, T. Takeda, N. Komuro, I.
- Journal Title
  
  Journal of Cardiology
  
  Volume: - Issue: 1 Pages: 69-75
- DOI
  10.1016/j.jjcc.2023.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08276, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-20K08398
[Journal Article] PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice2023
- Author(s)
  Fujiwara T, Takeda N, Hara H, Ishii S, Numata G, Tokiwa H, Katoh M, Maemura S, Suzuki T, Takiguchi H, Yanase T, Kubota Y, Nomura S, Hatano M, Ueda K, Harada M, Toko H, Takimoto E, Akazawa H, Morita H, Nishimura S, Komuro I.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 17 Pages: 162632-162632
- DOI
  10.1172/jci.insight.162632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16066, KAKENHI-PROJECT-22K08276, KAKENHI-PROJECT-23K07473, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02908, KAKENHI-PROJECT-23K27352
[Journal Article] Gender Difference Between Female and Male Cardiologists2022
- Author(s)
  Nakayama Atsuko、Kodera Satoshi、Morita Hiroyuki、Fujiwara Takayuki、Takeda Norifumi、Komuro Issei
- Journal Title
  
  Int. Heart J.
  
  Volume: 63 Issue: 2 Pages: 264-270
- DOI
  10.1536/ihj.21-451
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2022-03-30
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10479, KAKENHI-PROJECT-19K19828, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-21K11211
[Journal Article] Factors associated with left ventricular reverse remodelling after percutaneous coronary intervention in patients with left ventricular systolic dysfunction2021
- Author(s)
  Adachi Y、Kiyosue A、Ando J、Kawahara T、Kodera S、Minatsuki S、Kikuchi H、Inaba T、Kiriyama H、Hirose K、Shinohara H、Saito A、Fujiwara T、Hara H、Ueda K、Sakakura K、Hatano M、Harada M、Takimoto E、Akazawa H、Morita H、Momomura S、Fujita H、Komuro I
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 239-239
- DOI
  10.1038/s41598-020-80491-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08097, KAKENHI-PROJECT-19K17667, KAKENHI-PROJECT-18K08096, KAKENHI-PROJECT-21H02908
[Journal Article] Late-onset right ventricular failure after continuous-flow left ventricular assist device implantation: case presentation and review of the literature2021
- Author(s)
  Hatano Masaru、Jimba Takahiro、Fujiwara Takayuki、Tsuji Masaki、Bujo Chie、Ishida Junichi、Amiya Eisuke、Kinoshita Osamu、Ono Minoru
- Journal Title
  
  Journal of Cardiology
  
  Volume: 21 Issue: 2 Pages: 364-6
- DOI
  10.1016/j.jjcc.2021.12.009
- Data Source
  KAKENHI-PROJECT-21K16110
[Journal Article] An Autopsy Case of Pulmonary Veno-Occlusive Disease Complicated with Chronic Obstructive Pulmonary Disease and Severe Pulmonary Hypertension2021
- Author(s)
  Suzuki Takaaki、Hirose Kimihiko、Tabei Fumiko、Sugishita Yasuyuki、Oka Teruaki、Ishii Satoshi、Fujiwara Takayuki、Takeda Norifumi、Komuro Issei、Itoh Nobuhiko
- Journal Title
  
  Int. Heart J.
  
  Volume: 62 Issue: 5 Pages: 1186-1190
- DOI
  10.1536/ihj.21-133
- NAID
  130008094039
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2021-09-29
- Language
  English
- Data Source
  KAKENHI-PROJECT-21K16110
[Journal Article] CXCR7 ameliorates myocardial infarction as a β arrestin-biased receptor2021
- Author(s)
  Ishizuka et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 3426-3426
- DOI
  10.1038/s41598-021-83022-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08510, KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19J13042, KAKENHI-PROJECT-19K17667
[Journal Article] Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice2021
- Author(s)
  Fujiwara Takayuki、Takeda Norifumi、Hara Hironori、Ishii Satoshi、Numata Genri、Tokiwa Hiroyuki、Maemura Sonoko、Suzuki Takaaki、Takiguchi Hiroshi、Kubota Yoshiaki、Seo Kinya、Sakata Asuka、Nomura Seitaro、Hatano Masaru、Ueda Kazutaka、Komuro Issei
- Journal Title
  
  Circulation
  
  Volume: 144 Issue: 17 Pages: 1452-1455
- DOI
  10.1161/circulationaha.121.056219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08096, KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-21H02908
[Journal Article] Omega-3 fatty acid prevents the development of heart failure by changing fatty acid composition in the heart2020
- Author(s)
  Toko Haruhiro、Morita Hiroyuki、Katakura Masanori、Hashimoto Michio、Ko Toshiyuki、Bujo Satoshi、Adachi Yusuke、Ueda Kazutaka、Murakami Haruka、Ishizuka Masato、Guo Jiaxi、Zhao Chunxia、Fujiwara Takayuki、Hara Hironori、Takeda Norifumi、Takimoto Eiki、Shido Osamu、Harada Mutsuo、Komuro Issei
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15553-15553
- DOI
  10.1038/s41598-020-72686-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-19K17667
[Journal Article] Balloon Valvuloplasty to Treat Adult Symptomatic Pulmonary Valve Stenosis with Sequential Follow-Up Using Cardiac Magnetic Resonance Imaging in Combination with Echocardiography2020
- Author(s)
  Ishii Satoshi、Fujiwara Takayuki、Ando Jiro、Takeda Norifumi、Inaba Toshiro、Inuzuka Ryo、Komuro Issei
- Journal Title
  
  Int. Heart J.
  
  Volume: 61 Issue: 5 Pages: 1075-1078
- DOI
  10.1536/ihj.20-106
- NAID
  130007911321
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2020-09-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17667
[Journal Article] Remote cardiac rehabilitation is a good alternative of outpatient cardiac rehabilitation in the COVID-19 era2020
- Author(s)
  Nakayama Atsuko、Takayama Naoko、Kobayashi Momoko、Hyodo Kanako、Maeshima Naomi、Takayuki Fujiwara、Morita Hiroyuki、Komuro Issei
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: 25 Issue: 1 Pages: 1-1
- DOI
  10.1186/s12199-020-00885-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K19828, KAKENHI-PROJECT-19K17667
[Journal Article] Inhibition of transforming growth factor-β signaling in myeloid cells ameliorates aortic aneurysmal formation in Marfan syndrome2020
- Author(s)
  Hara Hironori、Maemura Sonoko、Fujiwara Takayuki、Takeda Norifumi、Ishii Satoshi、Yagi Hiroki、Suzuki Takaaki、Harada Mutsuo、Toko Haruhiro、Kanaya Tsubasa、Ijichi Hideaki、Moses Harold L.、Takimoto Eiki、Morita Hiroyuki、Akazawa Hiroshi、Komuro Issei
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 11 Pages: e0239908-e0239908
- DOI
  10.1371/journal.pone.0239908
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08484, KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-18K08097, KAKENHI-PROJECT-19K17667
[Journal Article] Cause or Result?2020
- Author(s)
  Fujiwara Takayuki、Takeda Norifumi
- Journal Title
  
  Int. Heart J.
  
  Volume: 61 Issue: 4 Pages: 633-635
- DOI
  10.1536/ihj.20-417
- NAID
  130007882194
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2020-07-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17667
[Journal Article] Effect of Treatment by Female Cardiologists on Short-Term Readmission Rates of Patients Hospitalized With Cardiovascular Diseases2019
- Author(s)
  Nakayama A, Morita H, Fujiwara T, Komuro I
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 9 Pages: 1937-1943
- DOI
  10.1253/circj.CJ-19-0357
- NAID
  130007695017
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-08-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17667, KAKENHI-PROJECT-19K19828, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-17H04061
[Journal Article] Activation of TGF-β signaling in an aortic aneurysm in a patient with Loeys-Dietz syndrome caused by a novel loss-of-function variant of TGFBR1.2019
- Author(s)
  Hara H, Takeda N, Fujiwara T, Yagi H, Maemura S, Kanaya T, et al.
- Journal Title
  
  Hum Genome Var
  
  Volume: 6 Issue: 1 Pages: 6-6
- DOI
  10.1038/s41439-019-0038-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17667
[Journal Article] Unique Mechanism by Which <i>TGFBR1</i> Variants Cause 2 Distinct System Diseases　― Loeys-Dietz Syndrome and Multiple Self-Healing Squamous Epithelioma ―2019
- Author(s)
  Fujiwara Takayuki、Takeda Norifumi、Ishii Satoshi、Morita Hiroyuki、Komuro Issei
- Journal Title
  
  Circulation Reports
  
  Volume: 1 Issue: 11 Pages: 487-492
- DOI
  10.1253/circrep.CR-19-0098
- NAID
  130007742756
- ISSN
  2434-0790
- Year and Date
  2019-11-08
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08484, KAKENHI-PROJECT-19K17667
[Presentation] Investigation of the mechanism of microvessel remodeling in pulmonary hypertension using spatiotemporal multi-scale imaging system2023
- Author(s)
  Takayuki Fujiwara
- Organizer
  第7回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-23K07473
[Presentation] PGC-1a mediated angiogenesis ameliorates pulmonary hypertension in mice2022
- Author(s)
  Takayuki Fujiwara
- Organizer
  第86回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16110
[Presentation] Three-dimensional visualization of adaptive angiogenic response in pulmonary hypertension2022
- Author(s)
  Takayuki Fujiwara
- Organizer
  心血管代謝週間2022
- Invited
- Data Source
  KAKENHI-PROJECT-21K16110
[Presentation] Investigation of the mechanism of microvessel remodeling in pulmonary hypertension using spatiotemporal multi-scale imaging system2021
- Author(s)
  Takayuki Fujiwara
- Organizer
  第5回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-21K16110
[Presentation] 新たな三次元病理病態解析が解き明かす肺高血圧症における微小血管リモデリングの意義とその治療応用2021
- Author(s)
  藤原隆行
- Organizer
  第50回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-21K16110
[Presentation] PGC-1a mediated angiogenesis ameliorates pulmonary hypertension in mice2021
- Author(s)
  Takayuki Fujiwara
- Organizer
  第5回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-21K16110
[Presentation] A novel three-dimensional visualization system revealed an essential adaptive angiogenic response in pulmonary hypertension2021
- Author(s)
  藤原　隆行
- Organizer
  第28回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元病理病態解析が解き明かす肺高血圧症における微小血管リモデリングの意義とその治療応用2020
- Author(s)
  藤原　隆行
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 三次元イメージングで解き明かす肺高血圧症の微小血管新生の意義2020
- Author(s)
  藤原　隆行
- Organizer
  第5回肺高血圧症肺循環学会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元的形態解析手法によって明らかとなった肺高血圧症の病態初期の微小血管リモデリングの意義2020
- Author(s)
  藤原　隆行
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元的形態解析手法によって明らかとなった肺高血圧症の微小血管リモデリングとその治療的意義2020
- Author(s)
  藤原　隆行
- Organizer
  第257回日本循環器学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元イメージングが解き明かす肺高血圧症の病態初期の微小血管リモデリングの意義とその治療応用2020
- Author(s)
  藤原　隆行
- Organizer
  第61回日本脈管学会総会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元病理病態解析が解き明かす肺高血圧症における微小血管リモデリングの意義とその治療応用2020
- Author(s)
  藤原　隆行
- Organizer
  第56回高血圧疾患モデル学会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元的形態解析手法によって明らかとなった肺高血圧症の病態初期の微小血管リモデリングの意義2019
- Author(s)
  藤原隆行
- Organizer
  第23回日本心血管内分泌代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] 新たな三次元的形態解析手法によって明らかとなった肺高血圧症の微小血管リモデリングの意義2019
- Author(s)
  藤原隆行
- Organizer
  脳心血管抗加齢研究会2019
- Data Source
  KAKENHI-PROJECT-19K17667
[Presentation] A novel three-dimensional visualization system demonstrates an essential adaptive angiogenic response in the early phase of pulmonary hypertension2019
- Author(s)
  藤原隆行
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K17667

1. 武田憲文 (60436483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. AKAZAWA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 東口治弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 中山敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 上田和孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 常盤洋之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujiwara Takayuki 藤原 隆行

Takayuki Fujiwara 藤原 隆行

Research Projects

Research Products

Co-Researchers

肺細動脈内皮細胞の機能変容に焦点を当てた新規肺高血圧モデルの病態解明と治療法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

三次元可視化システムによる難治性血管疾患の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of pathophysiology of hereditary pulmonary hypertension using novel 3D imaging systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Three-dimensional pathophysiological analysis of pulmonary hypertension using tissue-clearing method and mutiphoton microscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The ratio of TAPSE to PASP predicts prognosis in lung transplant candidates with pulmonary arterial hypertension2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic value of follow-up vasoreactivity test in pulmonary arterial hypertension2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gender Difference Between Female and Male Cardiologists2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Factors associated with left ventricular reverse remodelling after percutaneous coronary intervention in patients with left ventricular systolic dysfunction2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Late-onset right ventricular failure after continuous-flow left ventricular assist device implantation: case presentation and review of the literature2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Autopsy Case of Pulmonary Veno-Occlusive Disease Complicated with Chronic Obstructive Pulmonary Disease and Severe Pulmonary Hypertension2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] CXCR7 ameliorates myocardial infarction as a β arrestin-biased receptor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice2021

Author(s)

Journal Title

DOI

Fujiwara Takayuki 藤原隆行

Takayuki Fujiwara 藤原隆行

[Journal Article] Unique Mechanism by Which <i>TGFBR1</i> Variants Cause 2 Distinct System Diseases　― Loeys-Dietz Syndrome and Multiple Self-Healing Squamous Epithelioma ―2019