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TSUBOYAMA KOTARO  坪山 幸太郎

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Tsuboyama Kotaro  坪山 幸太郎

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Researcher Number 40850681
Affiliation (Current) 2026: 東京大学, 生産技術研究所, 講師
2026: 大阪大学, 蛋白質研究所, 特任講師(常勤)
Affiliation (based on the past Project Information) *help 2023 – 2026: 東京大学, 生産技術研究所, 講師
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (III) / Transformative Research Areas, Section (IV) / Basic Section 43040:Biophysics-related / Basic Section 43040:Biophysics-related / Medium-sized Section 48:Biomedical structure and function and related fields / Transformative Research Areas, Section (II) / 0701:Biology at molecular to cellular levels, and related fields
Except Principal Investigator
Basic Section 44010:Cell biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords
Principal Investigator
人工タンパク質 / 大規模測定法 / 機械学習 / タンパク質安定性 / 血液脳関門 BBB / タンパク質恒常性 / Heroタンパク質 / 共有結合 / 深層学習 / タンパク質 / 構造安定性 … More
Except Principal Investigator
… More 大規模スクリーニング / 生体膜 / タンパク質 / 両親媒性αヘリックス / 脂質結合ドメイン / CLiB assay / エンハンサー / 天然変性領域 / アクティベーター / 転写因子 / 転写制御 Less
  • Research Projects

    (10 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (3 People)
  •  任意の寿命を持つ人工タンパク質を生成するAI開発Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2026 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  De novoタンパク質によるタンパク質相互作用最適化過程の全容解明Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2026 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (IV)
    • Research Institution
      The University of Tokyo
  •  超解像イメージングと大規模定量技術による転写因子動作原理の解明

    • Principal Investigator
      深谷 雄志
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo
  •  人工タンパク質とAIによる、タンパク質寿命決定の分子メカニズム解析Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      The University of Tokyo
  •  大規模データとAIによる、GPCRの折り畳み・輸送制御規則の解析Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      The University of Tokyo
  •  自然を超える、「新奇」共有結合形成酵素の創成Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      The University of Tokyo
  •  機能性超天然変性タンパク質の網羅的探索とその分子機構解明Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  血液脳関門の透過性の超大規模解析とその予測AIモデル構築Principal Investigator

    • Principal Investigator
      坪山 幸太郎
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      The University of Tokyo
  •  タンパク質-膜結合メカニズムの基本原理を理解するための膜結合モジュール大規模解析

    • Principal Investigator
      西村 多喜
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Osaka University
  •  Highly precise prediction model on protein folding stabilityPrincipal Investigator

    • Principal Investigator
      Tsuboyama Kotaro
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0701:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo

All 2025 2024

All Presentation

  • [Presentation] High-throughput screening for the development of lipid-binding probes2025

    • Author(s)
      Taki Nishimura, Kotaro Tsuboyama, Yuki Nakagaki, Eiji Yamamoto, Noboru Mizushima
    • Organizer
      IPR International Conference 2025
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K02019
  • [Presentation] Development and Engineering of Lipid Binding Probes2024

    • Author(s)
      Taki Nishimura, Kotaro Tsuboyama
    • Organizer
      Cell Bio 2024 Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K02019
  • 1.  深谷 雄志 (00786163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  西村 多喜 (70552991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  JI JIA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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