Hanajiri Ryo 葉名尻良

Researcher Number	40861810
Other IDs
Affiliation (Current)	2026: 名古屋大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2026: 名古屋大学, 医学部附属病院, 助教 2021 – 2024: 名古屋大学, 医学部附属病院, 助教 2020: 名古屋大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator キメラ抗原受容体 / HLA / 免疫細胞療法 / CRISPRスクリーニング / CAR-T細胞療法 / 成人T細胞白血病 / 臍帯血 / 抗原特異的T細胞 / 細胞療法 / 免疫療法

CD4/CD8二重陰性CAR-T細胞の分子基盤解明と持続性向上への応用Principal Investigator
- Principal Investigator
  
  葉名尻良
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
CRISPR screening of B-cell lymphoma to enhance CAR-T therapyPrincipal Investigator
- Principal Investigator
  
  葉名尻良
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Adoptive immunotherapy for adult T-cell leukemia/lymphoma with ex vivo expanded multi-tumor associated antigen specific cytotoxic T-cellsPrincipal Investigator
- Principal Investigator
  
  Hanajiri Ryo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Simple and early prediction of severe CAR-T-related adverse events after Axi-cel infusion by initial high fever2025
- Author(s)
  Wakabayashi H, Terakura S, Ishigiwa K, Ohara F, Hirano S, Yokota H, Kuwano S, Furukawa K, Shimada K, Sato T, Hanajiri R, Kiyoi H.
- Journal Title
  
  Int J Hematol
  
  Volume: - Issue: 1 Pages: 106-116
- DOI
  10.1007/s12185-025-03957-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K15323
[Journal Article] Development and optimization of Eva1 (MPZL2) targeting chimeric antigen receptor T cells2025
- Author(s)
  Osaki Masahide、Terakura Seitaro、Hirano Shiho、Iwasa Takuma、Hatanaka Kanako C、Hatanaka Yutaka、Sunagawa Masaki、Kokuryo Toshio、Adachi Yoshitaka、Takeuchi Yuki、Hanajiri Ryo、Sakanaka Chie、Murata Makoto、Ebata Tomoki、Kiyoi Hitoshi
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 13 Issue: 5 Pages: e009825-e009825
- DOI
  10.1136/jitc-2024-009825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15323
[Journal Article] Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway2024
- Author(s)
  Adachi Y, Terakura S, Osaki M, Okuno Y, Sato Y, Sagou K, Takeuchi Y, Yokota H, Imai K, Steinberger P, Leitner J, Hanajiri R, Murata M, Kiyoi H.
- Journal Title
  
  Nat Commun
  
  Volume: 15(1) Issue: 1 Pages: 10376-10376
- DOI
  10.1038/s41467-024-54794-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-23K24140, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-24K11557, KAKENHI-PROJECT-23K15323
[Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023
- Author(s)
  Takagi Erina、Terakura Seitaro、Fujigaki Hidetsugu、Okamoto Akinao、Miyao Kotaro、Sawa Masashi、Morishita Takanobu、Goto Tatsunori、Ozawa Yukiyasu、Nishida Tetsuya、Fukushima Nobuaki、Ozeki Kazutaka、Hanajiri Ryo、Saito Kuniaki、Murata Makoto、Tomita Akihiro、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 4 Pages: 462-471
- DOI
  10.1007/s12185-023-03648-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15323, KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K27843
[Journal Article] Dual CAR-T Cells Targeting CD19 and CD37 Are Effective in Target Antigen Loss B-cell Tumor Models2023
- Author(s)
  Imai Kanae、Takeuchi Yuki、Terakura Seitaro、Okuno Shingo、Adachi Yoshitaka、Osaki Masahide、Umemura Koji、Hanajiri Ryo、Shimada Kazuyuki、Murata Makoto、Kiyoi Hitoshi
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 23 Issue: 3 Pages: 381-393
- DOI
  10.1158/1535-7163.mct-23-0408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K15323
[Journal Article] Cellular kinetics and outcome of tisagenlecleucel for diffuse large B-cell lymphoma2023
- Author(s)
  葉名尻良、古川勝也、中島麻梨絵、牛島洋子、島田和之、石川裕一、寺倉精太郎、村田誠、清井仁
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 3 Pages: 167-174
- DOI
  10.11406/rinketsu.64.167
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17375, KAKENHI-PROJECT-23K15323
[Journal Article] Risk factors for CAR-T cell manufacturing failure among DLBCL patients: A nationwide survey in Japan2023
- Author(s)
  Jo T, Yoshihara S, Okuyama Y, Fujii K, Henzan T, Kahata K, Yamazaki R, Takeda W, Umezawa Y, Fukushima K, Ashida T, Yamada-Fujiwara M, Hanajiri R, Yonetani N, Tada Y, Shimura Y, Nishikii H, Shiba N, Mimura N, Ando J, Sato T, Nakashima Y, Ikemoto J, Iwaki K, Fujiwara SI, Ri M, Nagamura-Inoue T, Tanosaki R, Arai Y.
- Journal Title
  
  British Journal of Haematology
  
  Volume: - Issue: 2 Pages: 256-266
- DOI
  10.1111/bjh.18831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17375, KAKENHI-PROJECT-21K16267, KAKENHI-PROJECT-23K15323
[Journal Article] Myelodysplastic syndrome with trisomy 8 presenting periodic fever and multiple MEFV gene variants outside exon 10: a case report2023
- Author(s)
  Noriyuki Takahashi, Ryo Hanajiri, Masashi Suzuki, Chise Anan, Atsushi Inagaki, Dai Kishida, Shohei Ozawa, Sho Kohri, Nobuhide Kamiya, Motoki Sato, Juichi Sato
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 85 Issue: 1 Pages: 195-203
- DOI
  10.18999/nagjms.85.1.195
- ISSN
  0027-7622
- URL
  https://nagoya.repo.nii.ac.jp/records/2004930
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10375, KAKENHI-PROJECT-20K17375
[Journal Article] Downregulation of HLA class II is associated with relapse after allogeneic stem cell transplantation and alters recognition by antigen-specific T cells2022
- Author(s)
  Adachi Yoshitaka、Sakai Toshiyasu、Terakura Seitaro、Shiina Takashi、Suzuki Shingo、Hamana Hiroshi、Kishi Hiroyuki、Sasazuki Takehiko、Arase Hisashi、Hanajiri Ryo、Goto Tatsunori、Nishida Tetsuya、Murata Makoto、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 3 Pages: 371-381
- DOI
  10.1007/s12185-021-03273-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17375, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-18H05279
[Journal Article] Composite CD79A/CD40 costimulatory endodomain enhances CD19CAR-T cell proliferation and survival2021
- Author(s)
  Julamanee Jakrawadee、Terakura Seitaro、Umemura Koji、Adachi Yoshitaka、Miyao Kotaro、Okuno Shingo、Takagi Erina、Sakai Toshiyasu、Koyama Daisuke、Goto Tatsunori、Hanajiri Ryo、Hudecek Michael、Steinberger Peter、Leitner Judith、Nishida Tetsuya、Murata Makoto、Kiyoi Hitoshi
- Journal Title
  
  Molecular Therapy
  
  Volume: － Issue: 9 Pages: 2677-2690
- DOI
  10.1016/j.ymthe.2021.04.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] 大細胞型B細胞リンパ腫患者に対するCAR-T細胞療法の高齢者と若年者における効果と安全性の比較2025
- Author(s)
  葉名尻　良, 佐藤貴彦, 古川勝也, 牛島洋子, 島田和之, 石川裕一, 寺倉精太郎, 清井仁
- Organizer
  第47回日本造血・免疫細胞療法学会総会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] Axi-cel投与後早期の発熱による重症CAR-AEの予測2025
- Author(s)
  若林浩也, 寺倉精太郎, 石際康平, 小原史也, 平野志帆, 横田裕史, 桑野史穂美, 古川勝也, 島田和之, 佐藤貴彦, 葉名尻良, 清井仁
- Organizer
  第47回日本造血・免疫細胞療法学会総会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] CD79A/CD40を共刺激ドメインとするCD19CAR-Tのメタボローム解析を用いた包括的代謝検討2024
- Author(s)
  竹内裕貴, 寺倉精太郎, 平野志帆, 横田裕史, 桑野史穂美, 尾崎正英, 安達慶高, 今井奏衣, ジャクラワディー・ジュラマニー , 葉名尻良, 村田誠, 清井仁
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] CAR-T輸注時にCMRのDLBCL患者におけるCAR-Tの増殖と治療成績2024
- Author(s)
  葉名尻良, 佐藤貴彦, 古川勝也, 牛島洋子, 島田和之, 石川裕一, 寺倉精太郎, 清井仁
- Organizer
  第46回日本造血・免疫細胞療法学会総会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] 末梢血CAR T細胞におけるCD4/CD8比がB細胞リンパ腫の治療効果と毒性に与える影響2024
- Author(s)
  葉名尻　良, 佐藤貴彦, 古川勝也, 牛島洋子, 島田和之, 石川裕一, 寺倉精太郎, 清井仁
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] 重症サイトカイン放出症候群はB細胞リンパ腫に対するCAR-T療法の遷延性血球減少症と関連している2023
- Author(s)
  葉名尻良, 佐藤貴彦, 古川勝也, 牛島洋子, 島田和之, 石川裕一, 寺倉精太郎, 清井仁
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] CD79A/CD40を共刺激ドメインに持つCD19-CAR-Tの分子メカニズムの解明2023
- Author(s)
  竹内裕貴, 寺倉精太郎, 横田裕史, 桑野史穂美, 安達慶高, 今井奏衣, ジャクラワディージュラマニー, 葉名尻良, 村田誠, 清井仁
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15323
[Presentation] チサゲンレクルユーセル輸注後におけるCAR-Tの体内動態と治療成績の検討2022
- Author(s)
  竹内裕貴, 葉名尻良, 牛島洋子, 島田和之, 石川裕一, 後藤尚絵, 寺倉精太郎, 村田誠, 冨田章裕, 清井仁
- Organizer
  第11回日本血液学会東海地方会
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] The optimal signal can be obtained by fine-tuning the spacer length of CD37CAR-T cells2021
- Author(s)
  安達慶高, 奥野真吾, 寺倉精太郎, Julamanee Jakrawadee, 堺寿保, 宮尾康太郎, 梅村晃史, 村瀬篤史, 島田和之, 葉名尻良, 西田徹也, 村田誠, 清井仁
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] 高IgE症候群に併発したDLBCLの化学療法中に膿瘍を合併するもドレナージ術にて安全に治療可能であった１例2021
- Author(s)
  葉名尻良, 川島直実, 牛島洋子, 島田和之, 石川裕一, 寺倉精太郎, 西田徹也, 村田誠, 清井仁
- Organizer
  第10回日本血液学会東海地方会
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] Genome-wide CRISPR-Cas9 screening to identify the genes regulating human CAR-T cells proliferation2021
- Author(s)
  安達慶高, 寺倉精太郎, 奥野友介, 佐藤好隆, 尾崎正英, 今井奏衣, 梅村晃史, 堺寿保, 葉名尻良, 西田徹也, 村田誠, 清井仁
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] 高IgE症候群に併発したDLBCLの化学療法中に膿瘍を合併するもドレナージ術にて安全に治療可能であった１例2021
- Author(s)
  葉名尻良、川島直実、牛島洋子、島田和之、石川裕一、寺倉精太郎、西田徹也、村田誠、清井仁
- Organizer
  第10回日本血液学会東海地方会
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] CD37CAR-T細胞のスペーサーの長さを微調整することで最適なシグナルを得ることができる2021
- Author(s)
  安達慶高, 奥野真吾, 寺倉精太郎, Julamanee Jakrawadee, 堺寿保, 宮尾康太郎, 村瀬篤史, 尾﨑正英, 今井奏衣, 梅村晃史, 葉名尻良, 島田和之, 西田徹也, 村田誠, 清井仁
- Organizer
  第13回日本血液疾患免疫療法学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17375
[Presentation] 造血幹細胞移植におけるHLA 抗体の臨床的意義2021
- Author(s)
  葉名尻良
- Organizer
  第4回東海北陸HLA研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17375

1. 寺倉精太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Hanajiri Ryo 葉名尻 良

Research Projects

Research Products

Co-Researchers

CD4/CD8二重陰性CAR-T細胞の分子基盤解明と持続性向上への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CRISPR screening of B-cell lymphoma to enhance CAR-T therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Adoptive immunotherapy for adult T-cell leukemia/lymphoma with ex vivo expanded multi-tumor associated antigen specific cytotoxic T-cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Simple and early prediction of severe CAR-T-related adverse events after Axi-cel infusion by initial high fever2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development and optimization of Eva1 (MPZL2) targeting chimeric antigen receptor T cells2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual CAR-T Cells Targeting CD19 and CD37 Are Effective in Target Antigen Loss B-cell Tumor Models2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular kinetics and outcome of tisagenlecleucel for diffuse large B-cell lymphoma2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Risk factors for CAR-T cell manufacturing failure among DLBCL patients: A nationwide survey in Japan2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myelodysplastic syndrome with trisomy 8 presenting periodic fever and multiple MEFV gene variants outside exon 10: a case report2023

Author(s)

Journal Title

DOI

ISSN

URL

Language

Data Source

[Journal Article] Downregulation of HLA class II is associated with relapse after allogeneic stem cell transplantation and alters recognition by antigen-specific T cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Composite CD79A/CD40 costimulatory endodomain enhances CD19CAR-T cell proliferation and survival2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 大細胞型B細胞リンパ腫患者に対するCAR-T細胞療法の高齢者と若年者における効果と安全性の比較2025

Author(s)

Organizer

Hanajiri Ryo 葉名尻良