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Nakajima Kohei  中島 孝平

ORCIDConnect your ORCID iD *help
Researcher Number 40907771
Other IDs
Affiliation (Current) 2025: 北海道大学, 薬学研究院, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 北海道大学, 薬学研究院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / 0801:Pharmaceutical sciences and related fields
Except Principal Investigator
Basic Section 53010:Gastroenterology-related / Basic Section 49030:Experimental pathology-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
光化学反応 / 光感受性化合物 / がん / 光免疫療法 / 免疫チェックポイント阻害剤 / 生体イメージング
Except Principal Investigator
光免疫療法 / 内視鏡 / 癌関連線維芽細胞 / 膵癌 … More / マスト細胞 / 近赤外光線免疫療法 / 小児がん / 神経芽腫 / 抗GD2抗体 Less
  • Research Projects

    (5 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (12 People)
  •  マスト細胞を標的とした光免疫療法のアレルギー疾患への応用

    • Principal Investigator
      片岡 竜貴
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Iwate Medical University
  •  がん光免疫療法の光化学反応を促進する分子を利用した新規治療薬の開発Principal Investigator

    • Principal Investigator
      中島 孝平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Hokkaido University
  •  Development of endoscopic dual photoimmunotherapy targeting pancreatic cancer cells and cancer-associated fibroblasts

    • Principal Investigator
      桑谷 将城
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Hokkaido University
  •  がん特異的糖鎖抗原を用いた小児がんに対する近赤外光線免疫療法の確立:前臨床モデル

    • Principal Investigator
      長 祐子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Hokkaido University
  •  In vivo imaging of immune and inflammatory responses during cancer photoimmunotherapyPrincipal Investigator

    • Principal Investigator
      Nakajima Kohei
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Hokkaido University

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] In vivo imaging of acute physiological responses after treatment of cancer with near-infrared photoimmunotherapy2023

    • Author(s)
      Nakajima Kohei、Sugikawa Akiyo、Yasui Hironobu、Higashikawa Kei、Suzuki Chie、Natsume Takahiro、Suzuki Motofumi、Takakura Hideo、Tomita Mayu、Takahashi Sachi、Hirata Kenji、Magata Yasuhiro、Kuge Yuji、Ogawa Mikako
    • Journal Title

      Molecular Imaging and Biology

      Volume: 25 Issue: 4 Pages: 648-658

    • DOI

      10.1007/s11307-023-01822-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K18259, KAKENHI-PROJECT-23K14332, KAKENHI-PROJECT-23K24270, KAKENHI-PROJECT-23K24994
  • [Journal Article] Near-infrared photoimmunotherapy and anti-cancer immunity2023

    • Author(s)
      Nakajima Kohei、Ogawa Mikako
    • Journal Title

      International Immunology

      Volume: 36 Issue: 2 Pages: 57-64

    • DOI

      10.1093/intimm/dxad042

    • Data Source
      KAKENHI-PROJECT-23K14332
  • [Journal Article] Application of Imaging for Antibody-Based Cancer Therapies : Photoimmunotherapy and Immune Checkpoint Blockade Therapy2022

    • Author(s)
      Kohei Nakajima, Mikako Ogawa
    • Journal Title

      NIHON GAZO GAKKAISHI (Journal of the Imaging Society of Japan)

      Volume: 61 Issue: 6 Pages: 643-651

    • DOI

      10.11370/isj.61.643

    • ISSN
      1344-4425, 1880-4675
    • Year and Date
      2022-12-10
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Journal Article] PD1 blockade alters cell-cycle distribution and affects 3′-deoxy-3′-[18F]fluorothymidine uptake in a mouse CT26 tumor model2022

    • Author(s)
      Suzuki Motofumi、Matsuda Takuma、Nakajima Kohei、Yokouchi Yuta、Kuge Yuji、Ogawa Mikako
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 36 Issue: 11 Pages: 931-940

    • DOI

      10.1007/s12149-022-01782-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16813, KAKENHI-PROJECT-21K20706
  • [Journal Article] Reduction of tumor hypoxia by anti-PD-1 therapy assessed using pimonidazole and [18F]FMISO2022

    • Author(s)
      Nakajima Kohei、Homma Mitsunori、Suzuki Motofumi、Yokouchi Yuta、Matsuda Takuma、Takakura Hideo、Hirata Kenji、Kuge Yuji、Ogawa Mikako
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 108-109 Pages: 85-92

    • DOI

      10.1016/j.nucmedbio.2022.03.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16813, KAKENHI-PROJECT-21K20706
  • [Presentation] 光免疫療法のメカニズム解明および新規治療薬剤の開発に向けた検討2024

    • Author(s)
      中島 孝平, 吉田 藍子, 平田 甫, 宮崎 風香, 桒谷 将城, 坂本 直哉, 大場 雄介, 小川 美香子
    • Organizer
      北海道大学フォトエキサイトニクス研究拠点 第6回研究会
    • Data Source
      KAKENHI-PROJECT-23K14332
  • [Presentation] がんの新たな光治療法「光免疫療法」の細胞傷害メカニズム2024

    • Author(s)
      中島孝平, 小川美香子
    • Organizer
      日本薬学会 第144年会
    • Data Source
      KAKENHI-PROJECT-23K14332
  • [Presentation] Photoimmunotherapy using anti-GD2 antibody for neuroblastoma2023

    • Author(s)
      Jimei Zhao, Masahiro Ueki, Kohei Nakajima, Yuko Cho, Mikako Ogawa, Atsushi Manabe
    • Organizer
      Advances in Neuroblastoma Research meeting (ANR)2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07884
  • [Presentation] Influence of anti-PD-1 therapy on tumor hypoxia assessed with pimonidazole and [18F]FMISO2022

    • Author(s)
      Kohei Nakajima, Mitsunori Homma, Motofumi Suzuki, Yuta Yokouchi, Takuma Matsuda, Hideo Takakura, Kenji Hirata, Yuji Kuge, Mikako Ogawa
    • Organizer
      13th Congress of the World Federation of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Presentation] 抗PD-1抗体が腫瘍内の低酸素状態に及ぼす影響に関する低酸素PETイメージング剤を用いた検討2022

    • Author(s)
      中島 孝平, 本間 充憲, 鈴木 基史, 横内 勇太, 松田 拓真, 高倉 栄男, 平田 健司, 久下 裕司, 小川 美香子
    • Organizer
      第34回 バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Presentation] Anti-PD-1 therapy reduces tumor hypoxia: evaluation with pimonidazole and [18F]fluoromisonidazole as hypoxia probes2022

    • Author(s)
      Kohei Nakajima, Mitsunori Homma, Motofumi Suzuki, Yuta Yokouchi, Takuma Matsuda, Hideo Takakura, Kenji Hirata, Yuji Kuge, Mikako Ogawa
    • Organizer
      12th AACR-JCA joint conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Presentation] 腫瘍内の低酸素状態に抗PD-1療法が及ぼす影響に関する検討2022

    • Author(s)
      中島 孝平, 鈴木 基史, 高倉 栄男, 久下 裕司, 小川 美香子
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Presentation] PET and MR imaging of physiological responses after near-infrared photoimmunotherapy of cancer2021

    • Author(s)
      Kohei Nakajima, Akiyo Sugikawa, Hironobu Yasui, Kei Higashikawa, Hideo Takakura, Chie Suzuki, Yasuhiro Magata, Yuji Kuge, Mikako Ogawa
    • Organizer
      The 11th China-Japan-Korea Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Presentation] Evaluation of biological characteristics in photoimmunotherapy-treated tumors using PET and MRI2021

    • Author(s)
      中島 孝平, 安井 博宣, 東川 桂, 高倉 栄男, 間賀田 泰寛, 久下 裕司, 小川 美香子
    • Organizer
      第80回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20706
  • [Presentation] 光免疫療法が腫瘍に及ぼす機能的変化に関するFDG-/FMISO-PETおよびMRIを用いた検討2021

    • Author(s)
      中島孝平, 杉川晃代, 安井博宣, 東川桂, 高倉栄男, 鈴木千恵, 間賀田泰寛, 久下裕司, 小川美香子
    • Organizer
      第61回 日本核医学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20706
  • 1.  長 祐子 (50507952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  真部 淳 (20292849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  小川 美香子 (20344351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  樋田 泰浩 (30399919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  植木 将弘 (30815288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  片岡 竜貴 (20343254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  桑谷 将城 (50431375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  川久保 和道 (80633578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HIRATA Kenji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  鈴木 基史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  久下 裕司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  安井 博宣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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