Murayama Masakazu 村山正和

… Alternative Names

MURAYAMA Masakazu 村山正和

Less

Researcher Number	40927802
Other IDs
Affiliation (Current)	2026: 昭和医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2026: 昭和医科大学, 医学部, 助教 2022 – 2024: 昭和大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 頭頸部癌 / 腫瘍微小環境 / 癌免疫療法 / 腸内細菌 / 短鎖脂肪酸 / イソ酪酸

イソ酪酸のマクロファージへの作用機序解明とイソ酪酸基質バリンの抗腫瘍効果の検討Principal Investigator
- Principal Investigator
  
  村山正和
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Showa Medical University
Mechanistic Insights into Isobutyric Acid-Mediated Cancer Immune Responses in the Tumor MicroenvironmentkkPrincipal Investigator
- Principal Investigator
  
  MURAYAMA Masakazu
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Showa University

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice2025
- Author(s)
  Funayama Eiji, Kuramasu Atsuo et al.
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 182 Pages: 117749-117749
- DOI
  10.1016/j.biopha.2024.117749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08902, KAKENHI-PROJECT-22K09675, KAKENHI-PROJECT-23K18223, KAKENHI-PROJECT-23K14663, KAKENHI-PROJECT-23K27409, KAKENHI-PROJECT-23K14419
[Journal Article] Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit2024
- Author(s)
  Hosonuma Masahiro、Hirasawa Yuya、Kuramasu Atsuo、他
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 3 Pages: 752-762
- DOI
  10.1111/cas.16061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08902, KAKENHI-PROJECT-22K09675, KAKENHI-PROJECT-20K17431, KAKENHI-PROJECT-21K08785, KAKENHI-PROJECT-23K14663
[Journal Article] Butyricimonas is a key gut microbiome component for predicting postoperative recurrence of esophageal cancer2024
- Author(s)
  Otsuka Koji、Isobe Junya、Asai Yoshiyuki、Nakano Tomohisa、Hattori Kouya、et al.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 73 Issue: 2 Pages: 23-23
- DOI
  10.1007/s00262-023-03608-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14663, KAKENHI-PROJECT-22K08902, KAKENHI-PROJECT-22K09675, KAKENHI-PROJECT-20K17431, KAKENHI-PROJECT-23K27409, KAKENHI-PROJECT-21K08785, KAKENHI-PROJECT-23K18223
[Journal Article] Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody2024
- Author(s)
  Murayama Masakazu, Kuramasu Atsuo et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 11325-11325
- DOI
  10.1038/s41598-024-59677-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08902, KAKENHI-PROJECT-22K09675, KAKENHI-PROJECT-23K14663
[Journal Article] MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2DLow T cells2024
- Author(s)
  Toyoda Hitoshi, Kuramasu Atsuo et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 23401-23401
- DOI
  10.1038/s41598-024-73712-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08902, KAKENHI-PROJECT-22K09675, KAKENHI-PROJECT-23K14663, KAKENHI-PROJECT-23K14419
[Journal Article] Turicibacter and Acidaminococcus predict immune-related adverse events and efficacy of immune checkpoint inhibitor2023
- Author(s)
  Hamada Kazuyuki、Isobe Junya、Hattori Kouya、Horiike Atsushi、Kim Yun-Gi、Tsunoda Takuya、Yoshimura Kiyoshi et al.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1164724-1164724
- DOI
  10.3389/fimmu.2023.1164724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18223, KAKENHI-PROJECT-23K14663, KAKENHI-PROJECT-22K08902, KAKENHI-PROJECT-22K09675, KAKENHI-PROJECT-20K17431, KAKENHI-PROJECT-23K27409
[Presentation] 頭頸部癌微小環境に対する腸内細菌代謝産物短鎖脂肪酸の免疫学的影響2023
- Author(s)
  村山正和、細沼雅弘、倉増敦朗、吉村清
- Organizer
  第124回日本耳鼻咽喉科頭頸部外科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K09675
[Presentation] Effect of Short-Chain Fatty Acids on Head and Neck Cancer2023
- Author(s)
  村山正和、細沼雅弘、倉増敦朗、吉村清
- Organizer
  AAO-HNSF 2023 Annual Meeting & OTO Experience
- Data Source
  KAKENHI-PROJECT-22K09675
[Presentation] 短鎖脂肪酸による頭頸部癌微小環境に対する免疫学的修飾の試み2022
- Author(s)
  村山正和、細沼雅弘、倉増敦朗、吉村清
- Organizer
  第123回日本耳鼻咽喉科学会総会学術講演会
- Data Source
  KAKENHI-PROJECT-22K09675
[Presentation] 腸内細菌代謝産物短鎖脂肪酸AはT細胞活性化およびM1マクロファージ誘導を介して頭頸部がんに対する抗PD-1抗体療法の作用を増強する2022
- Author(s)
  村山正和、細沼雅弘、倉増敦朗、吉村清
- Organizer
  第7回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K09675
[Presentation] Short-chain fatty acid A, metabolites of intestinal bacteria, enhances the efficacy of anti-PD-1 therapy for head and neck cancer through activation of T cells and M1 macrophages.2022
- Author(s)
  村山正和、細沼雅弘、倉増敦朗、吉村清
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K09675

1. 吉村清 (30346564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 倉増敦朗 (90302091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. 細沼雅弘 (20836457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 金倫基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murayama Masakazu 村山 正和

MURAYAMA Masakazu 村山 正和

Research Projects

Research Products

Co-Researchers

イソ酪酸のマクロファージへの作用機序解明とイソ酪酸基質バリンの抗腫瘍効果の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanistic Insights into Isobutyric Acid-Mediated Cancer Immune Responses in the Tumor MicroenvironmentkkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Butyricimonas is a key gut microbiome component for predicting postoperative recurrence of esophageal cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2DLow T cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Turicibacter and Acidaminococcus predict immune-related adverse events and efficacy of immune checkpoint inhibitor2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] 頭頸部癌微小環境に対する腸内細菌代謝産物短鎖脂肪酸の免疫学的影響2023

Author(s)

Organizer

Data Source

[Presentation] Effect of Short-Chain Fatty Acids on Head and Neck Cancer2023

Author(s)

Organizer

Data Source

[Presentation] 短鎖脂肪酸による頭頸部癌微小環境に対する免疫学的修飾の試み2022

Author(s)

Organizer

Data Source

[Presentation] 腸内細菌代謝産物短鎖脂肪酸AはT細胞活性化およびM1マクロファージ誘導を介して頭頸部がんに対する抗PD-1抗体療法の作用を増強する2022

Author(s)

Organizer

Data Source

[Presentation] Short-chain fatty acid A, metabolites of intestinal bacteria, enhances the efficacy of anti-PD-1 therapy for head and neck cancer through activation of T cells and M1 macrophages.2022

Author(s)

Organizer

Data Source

Murayama Masakazu 村山正和

MURAYAMA Masakazu 村山正和