Kosuge Aika 小菅愛加

Researcher Number	40973293
Other IDs
Affiliation (Current)	2025: 愛知淑徳大学, 健康医療科学部, 助教
Affiliation (based on the past Project Information) *help	2024 – 2025: 愛知淑徳大学, 健康医療科学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related Except Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator 脳内炎症 / 血液脳関門 / うつ病 Except Principal Investigator 末梢免疫細胞 / 炎症性サイトカイン / 免疫応答 / うつ病バイオマーカー / 骨髄由来免疫抑制細胞MDSC / 炎症系サイトカイン / うつ病

血管内皮細胞由来CXCL7が惹起する血液脳関門破綻に着目したうつ病発症機構の解明Principal Investigator
- Principal Investigator
  
  小菅愛加
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Aichi Shukutoku University
Mechanisms of peripheral-CNS immune responses in the development of major depressive disorder induced by stress
- Principal Investigator
  
  鍋島俊隆
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Fujita Health University

All 2024

All Journal Article Presentation

[Journal Article] Chronic social defeat stress induces the down‐regulation of the <scp>Nedd4L‐GLT</scp>‐1 ubiquitination pathway in the prefrontal cortex of mice2024
- Author(s)
  Kosuge Aika、Kunisawa Kazuo、Iida Tsubasa、Wulaer Bolati、Kawai Tomoki、Tanabe Moeka、Saito Kuniaki、Nabeshima Toshitaka、Mouri Akihiro
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 168 Issue: 9 Pages: 2479-2494
- DOI
  10.1111/jnc.16100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27534
[Journal Article] Ido2 Deficiency Exacerbates Motor Impairment and Reduces Aryl Hydrocarbon Receptor Activity through Decreased Kynurenine in a Chronic Demyelinating Mouse Model2024
- Author(s)
  Kunisawa Kazuo、Hara Mitsuki、Yoshidomi Koyo、Kon Yuki、Yamamoto Yasuko、Fujigaki Suwako、Wulaer Bolati、Kosuge Aika、Tanabe Moeka、Saitoh Sei、Takahashi Kazuo、Saito Kuniaki、Nabeshima Toshitaka、Mouri Akihiro
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 62 Issue: 1 Pages: 109-122
- DOI
  10.1007/s12035-024-04263-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-23K27534
[Journal Article] Adolescent social isolation decreases colonic goblet cells and impairs spatial cognition through the reduction of cystine2024
- Author(s)
  Tanabe Moeka、Kunisawa Kazuo、Saito Imari、Kosuge Aika、Tezuka Hiroyuki、Kawai Tomoki、Kon Yuki、Yoshidomi Koyo、Kagami Akari、Hasegawa Masaya、Kubota Hisayoshi、Ojika Haruto、Fujii Tadashi、Tochio Takumi、Hirooka Yoshiki、Saito Kuniaki、Nabeshima Toshitaka、Mouri Akihiro
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 30 Issue: 5 Pages: 2137-2151
- DOI
  10.1038/s41380-024-02826-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27534, KAKENHI-PROJECT-24KJ2127
[Presentation] 社会的隔離ストレスによる大腸杯細胞の減少は腸内細菌叢を変容させ、空間認知機能障害を誘発する.2024
- Author(s)
  國澤和生、田辺萌夏、齋藤いまり、小菅愛加、河合智貴、窪田悠力、齋藤邦明、鍋島俊隆、毛利彰宏.
- Organizer
  第28回腸内細菌学会学術集会.
- Data Source
  KAKENHI-PROJECT-23K27534
[Presentation] 膜貫通型糖蛋白質Gpnmbは多発性硬化症の炎症反応に関与する.2024
- Author(s)
  國澤和生、今勇貴、吉富航洋、小菅愛加、鍋島俊隆、毛利彰宏.
- Organizer
  第36回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27534
[Presentation] ストレスにより惹起されるうつ病発症における末梢-中枢連関の関与.2024
- Author(s)
  國澤和生、小菅愛加、鍋島俊隆、毛利彰宏.
- Organizer
  第 74 回脳の医学・生物学研究会第 3 回日本神経化学会若手 KYOUEN 合同大会
- Data Source
  KAKENHI-PROJECT-23K27534
[Presentation] The spatial cognitive dysfunction and microglial activation induced by adolescent social isolation through the hypoproduction of cystine by the damage of colonic goblet cells2024
- Author(s)
  Moeka Tanabe, Kazuo Kunisawa, Imari Saito, Aika Kosuge, Hiroyuki Tezuka, Tomoki Kawai, Masaya Hasegawa, Hisayoshi Kubota, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri..
- Organizer
  World Congress Collegium Internationale Neuro-Psychopharmacologicum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27534
[Presentation] The involvement of splenic immune cells in the depression-like behaviors induced by chronic social defeat stress.2024
- Author(s)
  Moeka Ogawa, Kazuo Kunisawa, Aika Kosuge, Hiroyuki Tezuka, Toshitaka Nabeshima, Akihiro Mouri.
- Organizer
  World Congress Collegium Internationale Neuro-Psychopharmacologicum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27534

1. 鍋島俊隆 (70076751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 毛利彰宏 (20597851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 國澤和生 (60780773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 齋藤邦明 (80262765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 斉藤邦明

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. 山本康子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 藤垣英嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kosuge Aika 小菅 愛加

Research Projects

Research Products

Co-Researchers

血管内皮細胞由来CXCL7が惹起する血液脳関門破綻に着目したうつ病発症機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of peripheral-CNS immune responses in the development of major depressive disorder induced by stress

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Chronic social defeat stress induces the down‐regulation of the <scp>Nedd4L‐GLT</scp>‐1 ubiquitination pathway in the prefrontal cortex of mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ido2 Deficiency Exacerbates Motor Impairment and Reduces Aryl Hydrocarbon Receptor Activity through Decreased Kynurenine in a Chronic Demyelinating Mouse Model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adolescent social isolation decreases colonic goblet cells and impairs spatial cognition through the reduction of cystine2024

Author(s)

Journal Title

DOI

Data Source

[Presentation] 社会的隔離ストレスによる大腸杯細胞の減少は腸内細菌叢を変容させ、空間認知機能障害を誘発する.2024

Author(s)

Organizer

Data Source

[Presentation] 膜貫通型糖蛋白質Gpnmbは多発性硬化症の炎症反応に関与する.2024

Author(s)

Organizer

Data Source

[Presentation] ストレスにより惹起されるうつ病発症における末梢-中枢連関の関与.2024

Author(s)

Organizer

Data Source

[Presentation] The spatial cognitive dysfunction and microglial activation induced by adolescent social isolation through the hypoproduction of cystine by the damage of colonic goblet cells2024

Author(s)

Organizer

Data Source

[Presentation] The involvement of splenic immune cells in the depression-like behaviors induced by chronic social defeat stress.2024

Author(s)

Organizer

Data Source

Kosuge Aika 小菅愛加