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WATANABE Minoru  渡辺 稔

ORCIDConnect your ORCID iD *help
Researcher Number 50012638
Affiliation (based on the past Project Information) *help 1986 – 1999: Nagoya City University, Faculty of Pharmaceutical Sciences (Professor), 薬学部, 教授
1986: 名古屋市大, 薬学部, 教授
1986: Nagoya City University of Pharmacy School, Professor, 藥学部・藥品作用学教室, 教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
Except Principal Investigator
Biological pharmacy / Experimental pathology
Keywords
Principal Investigator
平滑筋 / smooth muscle / RT-PCR法 / AF64A / ムスカリン受容体 / RT-PCR / 心筋 / 虹彩散瞳筋 / mRNA / Kv4.3 … More / relaxation / iris dilator / ラット / PCR法 / クローニング / 冠動脈 / カリウムチャネル / イオンチャネル / 弛緩 / 副交感神経 / ムスカリン様作用 / Ca^<2+>依存性K^+チャネル / リアノジン受容体 / denervation effects / autonomic innervation / high potassium solution / muscarinic effect / Ca mobilization / 除神経効果 / 自律神経支配 / 高カリウム溶液 / Ca動態 / Patch clamp / Iris sphincter / 膜電流 / 単一細胞 / イオン電流 / パッチクランプ / 虹彩平滑筋 / contractile proteins / muscarinic receptors / ciliary gangrionectomy / skinned fiber / parasympathetic denervation / supersensitivity / GTP結合蛋白 / 筋小胞体機構 / ムスカリン受容体サブタイプ / 外科的除神経 / 除神経 / 収縮蛋白 / 定量的PCR / スキンドファイバー / 徐神経 / 虹彩縮瞳筋 / [Ca^<2+>]_i / iris sphincter / parasympathectomy / RT-PCR methods / muscatihic receptor / rat iris / 画像解析 / fura-2 / 虹彩 / 細胞内Ca^<2+>濃度 / 縮瞳筋 / 副交感神経除去 / ラット虹彩 / voltage-dependent Ca^<2+> channel / Ca^<2+>-dependent K^+ channel / arachidonic acid / HEK 293 cell / RT-PCR technique / A-type K current / Ca依存性Kチャネル / 早期不活性型K電流 / 内向き整流性Kチャネル / L型Ca^<2+>チャネル / 早期不活性型K^+電流 / L型Caチャネル / Ca^<2+>依存性K^+チャンネル / アラキドン酸 / HEK293細胞 / AタイプK電流 / PTX / muscarinic receptor / 電気生理 / AF64F / G蛋白質 / Kv1.4 / Kv4.2 / A type K current / heart / Xenopus oocyte / TRKI / IsK / 抗不整脈薬 / in situ hybridization / Kチャネル / intracellular Ca concentration / culrure / synapse formation / cardiac myocyte / autonomic merve / ミクロピアゾン酸 / シナプス形式 / 細胞内カルシウム濃度 / 培養 / シナプス形成 / 自律神経 / drug selectivity / coronary artery / tetraalkyl ammonium / Ca channel / K channel / cardiac muscle / ion channel / クロライドチャネル / 薬物選択性 / 完動脈 / 4級アンモニウム塩 / カルシウムチャネル / norepinephrine / vas deferens / superior cervical ganglion / neuro-muscular junction / cell culture / tissue culture / sympathetic nerve / ノルエピネフリン / 精管 / 上頚神経節 / 神経筋接合部 / 細胞培養 / 組織培養 / 交感神経 / 細胞内Ca濃度 / 高カリウム液 / Ca^<2+>スパーク / 局所遊離Ca^<2+> / 膜直下筋小胞体 / 興奮収縮連関 / レーザー共焦点顕微鏡 / 単離平滑筋細胞 / 電位依存性Caチャネル / Caホットスポット / Ca依存性K電流 / Caスパーク / 共焦点蛍光顕微鏡 / Ca遊離チャネル / 筋小胞体 … More
Except Principal Investigator
Histamine / Adrenaline / Acetylchline / Desensitization / Receptor / Autacoid / Chemical transmitter / コレシストキニン / ヒスタミン / アドレナリン / アセチルコリン / 脱感作用 / オータコイド;受容体 / 伝達物質 / Epithelial cell lines of rat thymus and thymoma / Effects of neonatal thymectomy / Effects of the introduction of athymic nude gene / Atrophy of fast twitch muscles / Dominant inheritance / Spontaneous thymoma / Mna strain / Rat of the Buffalo / 培養液へのデキサメサゾン添加効果 / 胸腺及び胸腺腫上皮細胞株 / 新生仔期胸腺摘出効果 / 無胸腺遺伝子導入効果 / 速筋萎縮 / 優性遺伝 / 自然発生胸腺腫 / Mna系ラット / Buffalo / ruthenium red / cardiac atrial myocyte / CaィイD12+ィエD1-induced CaィイD12+ィエD1 release / CaィイD12+ィエD1-activated ClィイD1-ィエD1 current / CaィイD12+ィエD1 spark / L-type CaィイD12+ィエD1 channel / CaィイD12+ィエD1 activated KィイD1+ィエD1 channel / smooth muscle / SHR / mRNA発現量 / 電流密度 / L型Caチャネル / Ca依存性Kチャネル / 負帰還機構 / Caスパーク / Clチャネル / 平滑筋 / 負帰環機構 / リアノジン受容体 / Caチャネル / BKチャネル / イオンチャネル Less
  • Research Projects

    (16 results)
  • Co-Researchers

    (22 People)
  •  細胞内情報伝達系における局所Ca^<2+>動態の画像解析とイオンチャネル活性化制御Principal Investigator

    • Principal Investigator
      渡辺 稔
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya City University
  •  EXPRESSION OF IONIC CHANNELS DURING CARDIOVASCULAR DISEASE

    • Principal Investigator
      IMAIZUMI Yuji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biological pharmacy
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  The mechanisms underlying nonspecific supersensitivity induced by parasympathetic denervation in rat iris sphincterPrincipal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  細胞内情報伝達系における局所Ca^<2+>動態の画像解析とイオンチャンネル活性化制御機構Principal Investigator

    • Principal Investigator
      渡辺 稔
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  Molecular Diversity of K Channels in Cardiovascular System.Principal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  Molecular analysis of muscarinic receptors and regulation mechanism of dilation in the rat iris.Principal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  Molecular biology of vascular and cordiac k channelsPrincipal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  Molecular piolcgical analysises of muscarinic receptore in the rat iris dilatorPrincipal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  Vascular and cardiac ionic channels and drug specificityPrincipal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  Pharmacology of peconstitued synapses in co-culture of autonomic neurons and smooth mescle cellsPrincipal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  Measurement of synaptic currents and changes in intracellular Ca concentration in smooth muscle cells co-cultured with autonomic nerve cells.Principal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University, Faculty of Pharmaceutical Science
  •  哺乳動物虹彩散瞳筋におけるCa動態とムスカリン様作用薬による弛緩Principal Investigator

    • Principal Investigator
      渡辺 稔
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Institution
      Nagoya City University
  •  Cellular Ca mobilization and muscarinic relaxation in mammalian iris dilator muscle.Principal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University, Faculty of Pharmaceutical Science
  •  Pharmaco-mechanical coupling in the iris sphincter musclePrincipal Investigator

    • Principal Investigator
      WATANABE Minoru
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  Studies on the Drug-Receptor Mechanisms of Chemical Transmitters and Autacoids

    • Principal Investigator
      ISHIDA Yukio
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokushima, Faculty of Pharmaceutical Sciences
  •  Pathogenetic relationship between spontaneous developments of thymoma and muscle abnormality in Buffalo/Mna rats.

    • Principal Investigator
      MATSUYAMA Mutsushi
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Aichi Cancer Center
  • 1.  IMAIZUMI Yuji (60117794)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 2.  OHYA Susumu (70275147)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  MURAKI Katsuhiko (20254310)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  KAWAI Tomoyuki (60152906)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  GILES Wayne
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  TAKEI Satomi (20188147)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  WALSH Michael
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MATSUYAMA Mutsushi (80073112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NISHI Yoshimi (50073101)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MASUDA Akira (50157202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ISHIDA Yukio (50035531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  GOMI Yasuo (80004563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKAYANAGI Issei (70012599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KIMURA Masayasu (60019099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  FUKUDA Hideomi (50080172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  山原 なつき (40226535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MICHAEL walsh
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  WAYNE giles
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  UYAMA Yoshiaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ANTHONY Kana
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  WALSH Michoe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  WALSH Micha
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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