OCHIAI Kuniyasu 落合邦康

Researcher Number	50095444
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2018: 日本大学, 歯学部, 特任教授 2005 – 2015: Nihon University, School of Dentistry, Professor, 歯学部, 教授 2002 – 2004: 明海大学, 歯学部, 教授 2000: Meikai University, School of Dentistry, Professor., 歯学部, 教授 1994 – 1999: NIHON UNIVERSITY,SCHOOL OF DENTISTRY AT MATSUDO,ASSISTANT PROFESSOR, 松戸歯学部, 講師 1993: 日本大学, 松戸歯学部, 講師(専任扱) 1987 – 1988: 日本大学, 松戸歯学部, 講師
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry / 病態科学系歯学(含放射線系歯学) Except Principal Investigator Morphological basic dentistry / Social dentistry / 病態科学系歯学(含放射線系歯学) / Pathobiological dentistry/Dental radiology / Surgical dentistry
Keywords	Principal Investigator 酪酸 / 歯周病 / アポトーシス / T細胞 / Butyric acid / Apoptosis / 線維芽細胞 / 脂肪酸 / Porphyromonas / Prevotella … More / IL-1β / 歯周病原細菌 / 短鎖脂肪酸 / Actinobacillus / 歯周病原性菌 / Short-chain fatty acid / Adhesion molecule / Fibroblast / T cell / tight junction / 上皮細胞 / 接着分子 / Adhesion molecules / T-cell Fibroblast / Fatty acids / Anaerobic bacteria. / Periodontitis / 嫌気性菌 / 接着因子 / 歯周病原菌 / Actinobacills / periodontopathic bacteria / 歯周病原生菌 / 膣内細菌 / 腸内細菌叢 / HIV / エピジェネティク制御 / n-酪酸 / 微生物間相互作用 / ウイルス / HDAC / 酸化ストレス / EBV / エピジェネティクス / 組織為害作用 / 組織侵入 / バイオフィルム / サイトカイン / 免疫抑制 … More Except Principal Investigator アポトーシス / 老化 / 医療・福祉 / 口腔ケア / 酪酸 / 揮発性脂肪酸 / T細胞 / CD58 / CD47 / CD44 / T CELLS / APOPTOSIS / P53 / FAS / BAX / Glucosyltransferase / Streptococcus mutans / IL-1alpha / IL-1beta / IL-6 / 高齢者 / 歯周病原性細菌 / ワクチン / インフルエンザ / elderly vaccination / influenza / oral vaccination / vaccine design / antigen:gel ratio / separated antigen / mixed antigen / gingival crevice / oral-supplementation / gel-encapsulated / gingival vaccine / elderly / gingival vaccination / gel vaccine / Inhibition of lactic acid / Dental caries prevention / S.mutans / 乳酸産生阻害 / 乳酸発酵阻害物質 / LDH阻害 / 乳酸生成阻害 / 齲蝕予防 / INFLAMMATORY CYTOKINES / BUTYRIC ACID / FIBR OBLAST / 歯肉 / 炎症性サイトカイン / 繊維芽細胞 / CASPASE / BCL-2 / VOLATILE FATTY ACID / Caspase / bci-2 / caspase / p53 / bcl-2 / immunological diagnostic method / monoclonal antibody / cariogenic plaque formation / transformants / rat model experiment / gtf gene / 免疫学的診断法 / 単クローン抗体 / 齲蝕原性歯垢形成 / 形質転換株 / ラット齲蝕実験 / gtf遺伝子 / Periodontopathic bacteria / Growth / 歯周病原性細菌 / IL-1β / IL-1α / 増殖 / 抗微生物作用 / 老化微生物 / カテキン / 口腔微生物 / 歯学 / 衛生 / サイトカイン / 歯周病原細菌 / 線維芽細胞 / ル-6 / ル-1 / 発育促進 / 病巣感染 / 口腔細菌 Less

Utilizing the sulcular epithelium as a vaccination route ideal for elderly vaccination
- Principal Investigator
  
  Cueno Marni
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Possibility antimicrobial gel to control of oral pathogens and prevent of systemic diseases among elderly
- Principal Investigator
  
  TAMURA Muneaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Oral bacterial control and prevention of systemic disease among elderly : effects and possible applications of oral antimicrobial gel
- Principal Investigator
  
  TAMURA Muneaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Effects of butyric acid producing bacteria on epigenetic gene regulation and systemic diseasesPrincipal Investigator
- Principal Investigator
  
  OCHIAI Kuniyasu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Possibility of the oral microorganism control in the elderly by a gel-entrapped catechin
- Principal Investigator
  
  TAMURA Muneaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Effects of Short-chain fatty acid on biofilm formation and bacterial invasionPrincipal Investigator
- Principal Investigator
  
  OCHIAI Kuniyasu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Apoptosis induced by butyric acid modulates immunoresponses : Role of epitherial cells and fibroblasts in inhibiting butyric acid-induced T cell apoptosisPrincipal Investigator
- Principal Investigator
  
  OCHIAI Kuniyasu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
  Meikai University
Effects of adhesion molecules and mechanism of gingival fibroblast rescue butyric acid-induced T-cell apoptosis.Principal Investigator
- Principal Investigator
  
  OCHIAI Kuniyasu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Attenuation of butyric acid-induced T cell apoptosis by human gingival fibroblast
- Principal Investigator
  
  OCHIAI Tamoko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Purification and molecular basis analysis of IL-1β like substance form periodontopathic bacteria.Principal Investigator
- Principal Investigator
  
  OCHIAI Kuniyasu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
  Nihon University
Analysis of T cell apoptosis induced by volatile fatty acids
- Principal Investigator
  
  OCHIAI Tomoko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
歯周病原細菌代謝産物による歯肉線維芽細胞の増殖及びアポトーシスの制御機構
- Principal Investigator
  
  落合智子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
歯周病原細菌代謝産物によるT細胞アポトーシス誘導機構の解析
- Principal Investigator
  
  OCHIAI Tomoko
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
A. a. 産生免疫抑制物質のT細胞ネットワークに及ぼす影響Principal Investigator
- Principal Investigator
  
  落合邦康
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
ル-1、ル-6の病原惟細菌感染促進機構の解析
- Principal Investigator
  
  追川哲雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Elucidation of the caries-inducing mechanism by S.mutans and development of a diagnostic method to estimate caries-risk.
- Principal Investigator
  
  FUKUSHIMA Kazuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University, School of Dentistry at Matsudo
ENHANCEMENT OF GROWTH OF PERIODONTOPATHIC BACTERIA BY PRO-INFLAMMATORY CYTOKINES
- Principal Investigator
  
  OCHIAI Tomoko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  NIHON UNIVERSITY
An Investigation of Inhibitory Agent against Acid Production of Oral Bacteria
- Principal Investigator
  
  IKEDA Tadashi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University School of Dentistry at Matsudo

[Book] 腸内細菌・口腔細菌と全身疾患2015
- Author(s)
  田村宗明，落合邦康
- Total Pages
  259
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15K11456
[Book] 腸内共生系のバイオサイエンス（財団法人日本ビフィズス菌センター編）2011
- Author(s)
  落合邦康
- Publisher
  丸善出版社株式会社
- Data Source
  KAKENHI-PROJECT-23592714
[Book] 腸内共生系のバイオサイエンス(財団法人日本ピフィズス菌センター編)2011
- Author(s)
  落合邦康
- Publisher
  丸善出版社株式会社
- Data Source
  KAKENHI-PROJECT-23592714
[Book] 化学療法の領域　「序　口腔感染症の意味論－口腔内細菌による全身疾患と口腔ケア－」2011
- Author(s)
  落合邦康
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-23592714
[Book] 口腔微生物学2008
- Author(s)
  落合邦康
- Total Pages
  435
- Publisher
  学建書院
- Data Source
  KAKENHI-PROJECT-18592011
[Book] Effects of short-chain fatty acids on the expression of adhesion molecules in Inhibiting butyric-acid induced T-cell apoptosis.2007
- Author(s)
  K. Ochiai
- Total Pages
  350
- Publisher
  Medimond, Bologna, Italy
- Data Source
  KAKENHI-PROJECT-18592011
[Book] A role of reactive oxygen species in mitochondria-, TNF-, and endoplasmic Reticulum stress-mediated apoptosis induces by butyric acid.2007
- Author(s)
  T. Kurita-Ochiai
- Total Pages
  350
- Publisher
  Medimond, Bologna, Italy
- Data Source
  KAKENHI-PROJECT-18592011
[Book] 唾液腺(唾液の成分と作用)2006
- Author(s)
  天野修(編)落合邦康
- Publisher
  学建書院
- Data Source
  KAKENHI-PROJECT-18592011
[Book] 口腔微生物学-感染と免疫-2006
- Author(s)
  落合邦康他編集
- Total Pages
  426
- Publisher
  学建書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591834
[Book] 口腔微生物学感染と免疫
- Author(s)
  梅本敏夫, 小川知彦, 落合邦康, 上西秀則, 清浦有祐, 藤村節夫, 前田伸子(編)
- Publisher
  学建書院
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] Gingival Periodontal Disease (PD) Level-Butyric Acid Affects the Systemic Blood and Brain Organ: Insights Into the Systemic Inflammation of Periodontal Disease2018
- Author(s)
  Marni E. Cueno, Kuniyasu Ochiai
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 1-13
- DOI
  10.3389/fimmu.2018.01158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11525
[Journal Article] Periodontal disease- level butyric acid putatively contributes to the ageing blood: A proposed linked between periodontal diseases and the ageing process2017
- Author(s)
  Cueno ME, Seki K, Ochiai K, Imai K
- Journal Title
  
  Mechanisms of Aging and Development
  
  Volume: 162 Pages: 100-105
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11525
[Journal Article] Porphyromonas gingivalis Suppresses Trophoblast Invasion by Soluble Factors.2017
- Author(s)
  Hirohata N, Komine-Aizawa S, Tamura M, Ochiai K, Sugitani M, Hayakawa S. .
- Journal Title
  
  J Periodontol
  
  Volume: 88 Issue: 12 Pages: 1366-1373
- DOI
  10.1902/jop.2017.170193
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04341, KAKENHI-PROJECT-15K11456
[Journal Article] Utilizing the age-related widening of the gingival crevice as a potential non-invasive vaccination route: prospects for elderly vaccination.2016
- Author(s)
  Cueno ME, Tamura M, Seki K, Ohya M, Ochiai K
- Journal Title
  
  Experimental Gerontology
  
  Volume: 75 Pages: 37-41
- DOI
  10.1016/j.exger.2015.11.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K11456, KAKENHI-PROJECT-26861580
[Journal Article] Middle-aged rats orally supplemented with gel-encapsulated catechin favourably increases blood cytosolic NADPH levels.2015
- Author(s)
  Cueno ME, Tamura M, Ochiai K
- Journal Title
  
  Phytomedicine
  
  Volume: 22 Issue: 4 Pages: 425-430
- DOI
  10.1016/j.phymed.2015.01.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K11456
[Journal Article] Passive ultrasonic irrigation in the presence of a low concentration of hydrogen peroxide enhances hydroxyl radical generation and bactericidal effect against <i>Enterococcus faecalis </i>2014
- Author(s)
  Kobayashi Y, Hayashi M, Yoshino F, Tamura M, Yoshida A, Ibi H, Lee M-C, Ochiai K, Ogiso B
- Journal Title
  
  Journal of Oral Science
  
  Volume: 56 Issue: 1 Pages: 35-39
- DOI
  10.2334/josnusd.56.35
- NAID
  130003393076
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23660047, KAKENHI-PROJECT-24593168, KAKENHI-PROJECT-24792045
[Journal Article] Similar physiological in Porphyromonas gingivalis ATCC33277 under hemin-excess and hemin-limited concentrations are putatively associated to different hydrogen peroxide function.2014
- Author(s)
  Cueno ME, Tamura M, Ohya M, Ochiai K
- Journal Title
  
  Anaerobe
  
  Volume: 28 Pages: 178-181
- DOI
  10.1016/j.anaerobe.2014.06.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24593168
[Journal Article] Ab initio modeling approach towards establishing the structure and docking orientation of the Porphyromonas gingivalis FimA.2014
- Author(s)
  Cueno ME, Nagano K, Imai K, Tamura M, Yoshimura F, Ochiai K
- Journal Title
  
  Journal of Molecular Graphics and Modelling
  
  Volume: 15 Pages: 65-71
- DOI
  10.1016/j.jmgm.2014.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24593168
[Journal Article] Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease.2014
- Author(s)
  Cueno ME, Imai K, Tamura M, Ochiai K
- Journal Title
  
  Cell Stress Chaperon
  
  Volume: 19 Issue: 2 Pages: 295-298
- DOI
  10.1007/s12192-013-0462-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24593168
[Journal Article] Structural significance of the β1K396 residue found in the Porphyromonas gingivalis sialidase β-propeller domain : A computational study with implications for novel therapeutics against periodontal disease.2014
- Author(s)
  Cueno ME, Kamio N, Imai K, Ohya M, Tamura M, Ochiai K
- Journal Title
  
  OMIC A Journal of Integrative Biology
  
  Volume: 18 Issue: 9 Pages: 591-599
- DOI
  10.1089/omi.2013.0152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24593168, KAKENHI-PROJECT-25862088
[Journal Article] Bactericidal effect of hydroxyl radicals generated from a low concentration hydrogen peroxide with ultrasound in endodontic treatment2014
- Author(s)
  Y. Kobayashi, M. Hayashi, F. Yoshino, M. Tamura, A. Yoshida, H. Ibi, MC. Lee, K. Ochiai and B. Ogiso
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 54 Issue: 3 Pages: 161-165
- DOI
  10.3164/jcbn.13-86
- NAID
  130004466753
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592814, KAKENHI-PROJECT-23660047, KAKENHI-PROJECT-24593168
[Journal Article] 歯周疾患の発症と進展におけるウイルスの関与第3回：ウイルスと歯周病との関連2013
- Author(s)
  小方頼昌, 加藤彩子, 今井健一, 落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73 Pages: 143-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Butyric acid retension in gingival tissue induces oxidative stress in jugular blood mitochondria2013
- Author(s)
  Marni E. Cueno
- Journal Title
  
  Cell Stress and Chaperones
  
  Volume: 18 Issue: 5 Pages: 661-665
- DOI
  10.1007/s12192-013-0409-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390398, KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-24792010
[Journal Article] Overlapping glycosylation sequon influences the glycosylation pattern of a chimeric protein expressed in tomato leaf and callus2013
- Author(s)
  Cueno ME, Imai K, Okamoto T, Ochiai K
- Journal Title
  
  J Biotechnol
  
  Volume: 164 Issue: 1 Pages: 9-12
- DOI
  10.1016/j.jbiotec.2012.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24792010
[Journal Article] Higher prevalence of Epstein-Barr virus DNA in deeper periodontal pockets of chronic periodontitis in Japanese patients2013
- Author(s)
  Kato A, Imai K, Ochiai K, Ogata Y
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 8 Pages: 1-5
- DOI
  10.1371/journal.pone.0071990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-25463229
[Journal Article] BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7 cells2013
- Author(s)
  Tsuda H, Zhao N, Imai K, Ochiai K, Yang P, Suzuki N
- Journal Title
  
  Bosn J Basic Med Sci
  
  Volume: 13 Pages: 271-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Orally supplemented catechin increases heme amounts and catalase activities in rat heart blood mitochondoria: A comparison between middle-aged and young rats.2013
- Author(s)
  Cueno ME, Tamura M, Imai K, Ochiai K
- Journal Title
  
  Experimental Gerontology
  
  Volume: 48 Pages: 1319-1322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593168
[Journal Article] 歯周疾患の発症と発展におけるウイルスの関与第2回：根尖性歯周炎とヘルペスウイルス感染2013
- Author(s)
  武市収, 小木曽文内, 今井健一, 落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73 Pages: 130-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Effect of microbial coinfection with HIV-1 and butyric acid-producing anaerobic bacteria on AIDS progression2013
- Author(s)
  Imai K,Ochiai K
- Journal Title
  
  J 0ral Biosci
  
  Volume: vol.55 Issue: 2 Pages: 55-60
- DOI
  10.1016/j.job.2013.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 病原細菌供給源としての口腔感染症―ラット口腔カンジダ感染モデルを用いた検討―2013
- Author(s)
  田村宗明，大屋　学，長船奈津美，落合邦康
- Journal Title
  
  無菌生物 J Germfree Life gnotobiol
  
  Volume: 43 Pages: 76-81
- Data Source
  KAKENHI-PROJECT-24593168
[Journal Article] Orally supplemented catechin increases heme amounts and catalase activities in rat heart blood mitochondoria: A comparison between middle-aged and young rats2013
- Author(s)
  Cueno ME, Tamura M, Imai K, Ochiai K
- Journal Title
  
  Experimental Gerontology
  
  Volume: 48 Issue: 11 Pages: 1319-1322
- DOI
  10.1016/j.exger.2013.08.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 歯周病の潜伏感染ウイルスの再活性化とがん細胞転移への影響2013
- Author(s)
  落合邦康
- Journal Title
  
  日大医学雑誌
  
  Volume: 72 Pages: 178-179
- NAID
  10031190212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7 cells2013
- Author(s)
  Tsuda H,Zhao N,Imai K,Ochiai K,Yang P,Suzuki N
- Journal Title
  
  Bosn J Basic Med Sci
  
  Volume: vol.13 Pages: 271-275
- URL
  http://www.bjbms.org/archives/2013-4/11-Tsuda.pdf#search
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 歯周病原細菌の産生する短鎖脂肪酸と難治性全身疾患2013
- Author(s)
  落合邦康
- Journal Title
  
  静脈経腸栄養
  
  Volume: 28 Pages: 945-952
- NAID
  130004487314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] 歯周疾患の発症と進展におけるウイルスの関与　第１回：歯周疾患の病因論におけるウイルスの意義.2013
- Author(s)
  今井健一，落合邦康
- Journal Title
  
  日本歯科評論
  
  Volume: 73 Pages: 151-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Cytokinin dehydrogenase differentially regulates cytokinin and indirectly affects hydrogen peroxidase accumulation in tomato leaf.2012
- Author(s)
  Cueno ME et al.
- Journal Title
  
  J. plant. physi
  
  Volume: 169(8) Issue: 8 Pages: 834-838
- DOI
  10.1016/j.jplph.2012.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843, KAKENHI-PROJECT-24792010
[Journal Article] Exploring the possible application of catechin(gel) for oral care of the elderly and disabled individuals2012
- Author(s)
  Tamura M, Ochiai K
- Journal Title
  
  JDSR
  
  Volume: (in press)
- NAID
  10030957811
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Exploring the possible application of catechin (gel) for oral care of the elderly and disabled individuals.2012
- Author(s)
  Tamura M et al.
- Journal Title
  
  JDSR
  
  Volume: 48 Issue: 2 Pages: 126-134
- DOI
  10.1016/j.jdsr.2012.02.004
- NAID
  10030957811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria.2012
- Author(s)
  Imai K et al.
- Journal Title
  
  Cell. Mol. Life Sci.
  
  Volume: 69(15) Issue: 15 Pages: 2583-2592
- DOI
  10.1007/s00018-012-0936-2
- NAID
  10029976312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] Exploring the possible application of catechin (gel) for oral care of the elderly and disabled individuals.2012
- Author(s)
  Tamura M, Ochiai K
- Journal Title
  
  JDSR
  
  Volume: 48 Pages: 126-134
- NAID
  10030957811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593168
[Journal Article] Microbial Interaction of Periodontopathic Bacterium Porphyromonas gingivalis and HIV -Possible Causal Link of Periodontal Diseases to AIDS Progression-2012
- Author(s)
  Imai K et al.
- Journal Title
  
  Current HIV Research
  
  Volume: 10 Issue: 3 Pages: 213-220
- DOI
  10.2174/157016212800618183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] Microbial interaction between HIV-1 and anaerobic bacteria producing butyric acid: its potential implication in AIDS progression.2012
- Author(s)
  Imai K et al.
- Journal Title
  
  Future virology
  
  Volume: 7(10) Issue: 10 Pages: 1005-1014
- DOI
  10.2217/fvl.12.92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714, KAKENHI-PROJECT-24592843
[Journal Article] Microbial Interaction of Periodontopathic Bacterium Porphyromonas gingivalis and HIV -Possible Causal Link of Periodontal Diseases to AIDS Progression2011
- Author(s)
  Imai K,Victriano AF,Ochiai K,Okamoto T
- Journal Title
  
  J. 0ral Biosci
  
  Volume: vol.53(3) Issue: 3 Pages: 213-220
- DOI
  10.1016/s1349-0079(11)80004-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Antimicrobial activity of gel-entrapped catechins toward oral microorganisms2011
- Author(s)
  Tamura M, Saito H, Kikuchi K, Ishigami T, Toyama Y, Takami M, Ochiai K
- Journal Title
  
  Biol Pharm Bull
  
  Volume: vol.34(5) Pages: 638-643
- NAID
  130000657773
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Hydroxyapatite不織布を用いたラット歯周病実験モデルの開発2011
- Author(s)
  田村宗明, 齋藤秀雄, 阿部和正, 石上友彦, 清水典佳, 落合邦康
- Journal Title
  
  日大歯学
  
  Volume: 85(3) Pages: 125-128
- NAID
  10031146278
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Novel histone deacetylase inhibitor NCH-51 activates latent HIV-1 gene expression2011
- Author(s)
  Ann Florence B
- Journal Title
  
  Fed.Eur.Biochem.Soc.Lett
  
  Volume: 585 Issue: 7 Pages: 1103-1111
- DOI
  10.1016/j.febslet.2011.03.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034, KAKENHI-PROJECT-23592714
[Journal Article] Butyric acid effects in the development of periodontitis and systemic diseases2011
- Author(s)
  Ochiai K, Imai K, Tamura M, Kurita-Ochiai T
- Journal Title
  
  J Oral Biosci
  
  Volume: 53(3) Pages: 213-220
- NAID
  10029494848
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Butyric acid effects in the development of periodontitis and systemic diseases.2011
- Author(s)
  Ochiai K
- Journal Title
  
  J Oral Biosci.
  
  Volume: 53 Pages: 213-220
- NAID
  10029494848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] Butyric acid effects in the development of periodontitis and systemic diseases2011
- Author(s)
  Ochiai K
- Journal Title
  
  J Oral Biosci
  
  Volume: 第53巻 Pages: 213-220
- NAID
  10029494848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Role of histone modification on transcriptional regulation and HIV-1 gene expression: possible mechanisms of periodontal diseases in AIDS progression2011
- Author(s)
  Imai K,Ochiai K
- Journal Title
  
  Journal of Oral Science
  
  Volume: 53 Issue: 1 Pages: 1-13
- DOI
  10.2334/josnusd.53.1
- NAID
  130000659030
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592714
[Journal Article] カテキンジェルの新開発とその有効性～口腔内の細菌に対する抗菌薬療法～2010
- Author(s)
  田村宗明, 落合邦康
- Journal Title
  
  難病と在宅ケア
  
  Volume: 第16巻 Pages: 60-62
- Data Source
  KAKENHI-PROJECT-21592664
[Journal Article] Zink and copper play a role in coaggregation in-hibiting actionof Porphyromonas gingiva-lis2009
- Author(s)
  M. Tamura, K. Ochiai
- Journal Title
  
  Oral Microbiol. Immunol 24
  
  Pages: 56-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] 歯周病原菌代謝産物・短鎖脂肪酸のプラーク形成菌遷移に及ぼす影響2008
- Author(s)
  田中一, 落合邦康
- Journal Title
  
  Journal of Germfree Life and Gnotobiology 38
  
  Pages: 120-123
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] Glycosylation of theOMP85 homolog of Porphyromonas gingivalis and its involvement in biofilm formation2008
- Author(s)
  R. Nakao, Y. Tashiro, N. Nomura, S. Kosono, K. Ochiai, H. Yonezawa, H. Wata-nabe, H. Senpuku.
- Journal Title
  
  Biochem. Biophys. Res. Communi 365
  
  Pages: 784-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] Butyric acid induces apoptosis in human fibroblasts.2008
- Author(s)
  T. Kurita-Ochiai
- Journal Title
  
  Journal of dental Research 87
  
  Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] Increased susceptibility to tumor necrosis factor-α in butyric acid-inducedapoptosis is caused by down-regulation of FLIP expression in Jurkat T cells2008
- Author(s)
  S. Seto, T. Kurita-Ochiai, K. Ochiai
- Journal Title
  
  Microbiol. Immunol 52
  
  Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] Butyric acid induces apoptosis in human fibroblasts2008
- Author(s)
  T. Kurita-Ochiai, S. Seto, M. Yamamoto, K. Otsuka, K. Abe, K. Ochiai
- Journal Title
  
  J. Dent. Res. 87
  
  Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] 口腔トレポネーマの膿瘍形成におよぼす短鎖脂肪酸の影響2007
- Author(s)
  菊池邦好, 黒田亘一郎、落合邦康
- Journal Title
  
  J. Germfree Life Gnotobiology 37
  
  Pages: 74-77
- NAID
  10019906785
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] 歯周病における短鎖脂肪酸の為害作用2007
- Author(s)
  落合邦康
- Journal Title
  
  日大歯学 81
  
  Pages: 213-221
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] 歯周病における短鎖脂肪酸の為害作用2007
- Author(s)
  落合邦康、阿部和正、落合智子
- Journal Title
  
  日大歯学 81
  
  Pages: 213-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] Characterization of the effects of butyric acid on cell proliferation, cell cycle, distribution and apoptosis.2006
- Author(s)
  T.Kurita-Ochiai
- Journal Title
  
  FEMS Immunol. Med. Microbiol. 47
  
  Pages: 67-74
- Data Source
  KAKENHI-PROJECT-18592011
[Journal Article] The immune system2006
- Author(s)
  Ochiai, K., Ochiai, T.
- Journal Title
  
  Oral Microbiology, 1^<st> Edition (Edited by Umemoto, T., Ogawa, T, Ochiai, K., et al.)
  
  Pages: 224-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591834
[Journal Article] Bacterial infection2006
- Author(s)
  Ochiai, K.
- Journal Title
  
  Oral Microbiology, 1^<st> Edition (Edited by Umemoto, T., Ogawa, T, Ochiai, K., et al.)
  
  Pages: 70-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591834
[Journal Article] Apoptosis induced by short-chain fatty acids modulates immunoresponses : Role of cell-to-cell communication in inhibiting butyric acid-induced T cell apoptosis.2005
- Author(s)
  K.Ochiai, T.Kurita-Ochiai
- Journal Title
  
  Bioscience Microflora 24・3
  
  Pages: 91-95
- NAID
  10016674500
- Data Source
  KAKENHI-PROJECT-16591834
[Patent] 口腔内嫌気性細菌用静菌剤2012
- Inventor(s)
  伊藤秀行，山田益巳，前野正夫，落合邦康，川戸貴行，田村宗明
- Industrial Property Rights Holder
  伊藤秀行，山田益巳，前野正夫，落合邦康，川戸貴行，田村宗明
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-01
- Data Source
  KAKENHI-PROJECT-24593168
[Patent] 口腔内好気性細菌用静菌剤2012
- Inventor(s)
  伊藤秀行，山田益巳，前野正夫，落合邦康，川戸貴行，田村宗明
- Industrial Property Rights Holder
  伊藤秀行，山田益巳，前野正夫，落合邦康，川戸貴行，田村宗明
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-01
- Data Source
  KAKENHI-PROJECT-24593168
[Patent] 保存安定性に優れた口腔用抗菌剤および口腔ケア用組成物2012
- Inventor(s)
  齋藤洋祐、高見正雄、草間なぎさ、田村宗明、落合邦康
- Industrial Property Rights Holder
  齋藤洋祐、高見正雄、草間なぎさ、田村宗明、落合邦康
- Industrial Property Rights Type
  特許
- Filing Date
  2012-12-27
- Overseas
- Data Source
  KAKENHI-PROJECT-24593168
[Patent] 保存安定性に優れた口腔用抗菌剤および口腔ケア用組成物2011
- Inventor(s)
  齋藤洋祐, 高見正雄, 草間なぎさ, 田村宗明, 落合邦康
- Industrial Property Rights Holder
  株式会社明治
- Patent Publication Number
  2011-287441
- Filing Date
  2011-12-28
- Data Source
  KAKENHI-PROJECT-21592664
[Patent] 保存安定性に優れた口腔用抗菌剤および口腔ケア用組成物2011
- Inventor(s)
  齋藤洋祐、高見正雄、草間なぎさ、田村宗明、落合邦康
- Industrial Property Rights Holder
  株式会社明治、日本大学
- Patent Publication Number
  2011-287441
- Filing Date
  2011-12-28
- Data Source
  KAKENHI-PROJECT-21592664
[Patent] 口腔常在菌叢調整剤およびこれを用いた口腔常在菌叢調整方法2008
- Inventor(s)
  高見正雄、外山義雄、田村宗明、落合邦康
- Industrial Property Rights Holder
  明治乳業株式会社、日本大学
- Patent Publication Number
  2010-064961
- Filing Date
  2008-09-09
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] S-PRGフィラーイオン水がCandida albicansに及ぼす影響－バイオフィルム形成抑制効果と酸化ストレスについて－2018
- Author(s)
  田村宗明，落合邦康
- Organizer
  第3回生体機能性材料’’S-PRGフィラー’’研究会
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 酪酸がNGF処理PC12細胞のストレス関連シグナルに及ぼす影響2017
- Author(s)
  関啓介，神尾宜昌，クエノマーニ，田村宗明，落合邦康，今井健一
- Organizer
  第60回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 慢性歯周炎患者に対するカテキンゲルの有効性2017
- Author(s)
  高井英樹，田村宗明，相羽悠喜子，中山洋平，落合邦康，今井健一，小方頼昌
- Organizer
  第60回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 次世代シークエンサーによる口腔ケア剤使用時における健康高齢者および障害者口腔細菌数の網羅的解析2016
- Author(s)
  田村宗明，大屋　学，関　啓介，阿部和正，落合邦康
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] Varying hemin concentrations affect Porphyromonas gingivalis strains differently2016
- Author(s)
  大屋　学，田村宗明，Marni Cueno，落合邦康
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 次世代シークエンサを用いた口腔ケア剤塗布による障害者口腔細菌叢の網羅的解析2016
- Author(s)
  田村宗明，藤井　航，落合邦康
- Organizer
  第31回日本静脈栄養経腸学会
- Place of Presentation
  マリンメッセ福岡（福岡県福岡市）
- Year and Date
  2016-02-25
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] ELIS とS-PRGジェルが歯周病原菌および一般病原菌に及ぼす影響2016
- Author(s)
  田村宗明，落合邦康
- Organizer
  第2回生体機能性材料’’S-PRGフィラー’’研究会
- Place of Presentation
  松風研修センター（京都府京都市）
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] アリルイソチオシアネートがCandida albicansに及ぼす影響2016
- Author(s)
  田村宗明，落合邦康，今井健一
- Organizer
  第58回歯科基礎医学会学術大会・総会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 健康高齢者口腔細菌数の網羅的解析－口腔ケア剤使用による影響－2016
- Author(s)
  田村宗明，落合邦康
- Organizer
  第49回　日本無菌生物ノートバイオロジー学会
- Place of Presentation
  仙台ガーデンパレス（宮城県仙台市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 茶カテキン含有口腔ジェルが障害者口腔の微生物叢に及ぼす影響2015
- Author(s)
  田村宗明，落合邦康
- Organizer
  第59回日本細菌学会関東支部総会
- Place of Presentation
  東京歯科大学新館血脇ホール（東京都千代田区）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 歯周病と老化との関連性：歯周病で見られる酪酸濃度が血液老化に及ぼす影響2015
- Author(s)
  クエノマーニ，田村宗明，落合邦康
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 新規バイオマテリアルS-PRGフィラーのCandida albicansの増殖と病原性に及ぼす影響2015
- Author(s)
  田村宗明，落合邦康
- Organizer
  私立大学戦略的研究基盤形成支援事業　26年度研究成果報告会
- Place of Presentation
  日本大学歯学部（東京都千代田区）
- Year and Date
  2015-03-14
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] S-PRGフィラーがCandida albicansに及ぼす影響2015
- Author(s)
  田村宗明，落合邦康
- Organizer
  第1回生体機能性材料’’S-PRGフィラー’’研究会
- Place of Presentation
  松風研修センター（京都府京都市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 茶カテキンを応用した口腔ジェルが障害者の口腔内歯周病原菌およびカンジダ菌数に及ぼす影響2015
- Author(s)
  田村宗明，藤井　航，吉田幸弘，相澤　恒，落合邦康
- Organizer
  第21回日本摂食・嚥下リハビリテーション学会学術大会
- Place of Presentation
  国立京都国際会議場（京都府京都市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 茶カテキン配合口腔湿潤ジェルの終末期患者への臨床効果について2015
- Author(s)
  永田千里，藤井　航，金森大輔，坂口貴代美，田村宗明，渡邉理沙，落合邦康，松尾浩一郎
- Organizer
  第10回日本歯科衛生学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-09-20
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] Periodontal disease and cellular aging: how are both connected?2015
- Author(s)
  Cueno ME, Tamura M, Ochiai K
- Organizer
  International Association of Gerontology and Geriatrics Congress 2015
- Place of Presentation
  チェンマイ（タイ）
- Year and Date
  2015-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 新規バイオマテリアルS-PRGフィラーのCandida albicansに及ぼす影響2015
- Author(s)
  田村宗明，大屋　学，関　啓介，阿部和正，落合邦康
- Organizer
  第48回　日本無菌生物ノートバイオロジー学会
- Place of Presentation
  広島大学（広島県広島市）
- Year and Date
  2015-01-30
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 要介護高齢者の口腔細菌叢コントロールを目的とした口腔ケア剤の開発2015
- Author(s)
  田村宗明, 藤井　航, 永田千里, 坂口貴代美, 落合邦康
- Organizer
  第26回日本老年歯科医学会総会・学術大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 障害者に対する口腔ケアジェルの臨床応用について2015
- Author(s)
  田村宗明，大屋　学，関　啓介，阿部　和正，落合邦康
- Organizer
  第88回細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] Butyric acid-based oral infection induces aging-related immunosenescence2015
- Author(s)
  Cueno ME, Tamura M, Ochiai K
- Organizer
  6th Congress of the Federation of Immunological Societies of Asia Oceania
- Place of Presentation
  シンガポール（シンガポール）
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 障害者におけるプラークコントロールレコードについて第2報：カテキンジェルの効果2015
- Author(s)
  今井光子，青柳康子，三田千和子，遠山和子，吉田幸弘，内田琢也，田村宗明，落合邦康，相澤　恒
- Organizer
  第32回日本障害者歯科学会総会および学術大会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] Gingival Mucosa as an Alternative Vaccination Route: Implications for Elderly Vaccination2015
- Author(s)
  Cueno ME, Tamura M, Ochiai K
- Organizer
  The International Conference on Multimodel Interraction, CMI2015
- Place of Presentation
  ベルリン（ドイツ）
- Year and Date
  2015-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 要介護高齢者の誤嚥性肺炎予防と健康維持を目的とした新規口腔ケア法2015
- Author(s)
  田村宗明，落合邦康
- Organizer
  第89回日本感染症学会学術講演会
- Place of Presentation
  国立京都国際会議場（京都府京都市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 次世代シークエンスを用いた口腔ケア剤使用時における健康高齢者口腔細菌数の網羅的解析2015
- Author(s)
  田村宗明，阿部和正，大屋　学，関　啓介，落合邦康
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11456
[Presentation] 茶カテキンを応用した口腔ジェルが経口および経管栄養高齢者の口腔細菌数に及ぼす影響2014
- Author(s)
  田村宗明、藤井　航、永田千里、坂口貴代美、大屋　学、落合邦康
- Organizer
  第20回日本摂食・嚥下リハビリテーション学会・共催学術大会
- Place of Presentation
  新宿NSビル（東京都新宿区）
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] A possible correlation between oral butyric acid and aging2014
- Author(s)
  落合邦康、Marni Cueno
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀、東京
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 新規口腔ケア剤による高齢者の口腔内カンジダ数減少効果2014
- Author(s)
  田村宗明，大屋　学，落合邦康
- Organizer
  第47回　日本無菌生物ノートバイオロジー学会
- Place of Presentation
  アルカディア市ヶ谷（東京）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 口腔細菌はインフルエンザウィルス感染を促進する2014
- Author(s)
  神尾宜目、今井健一、田村宗明、Marni Cueno、粛藤夕子、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀、東京
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔細菌のウィルス感染症促進作用　－ＥＢＶおよびインフルエンザ感染に及ぼす影響－2014
- Author(s)
  今井健一、神尾宜昌、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 新規植物抽出成分のCandida albicans病原性抑制効果2014
- Author(s)
  田村宗明，大屋　学，関　啓介，阿部　和正，落合邦康
- Organizer
  第87回細菌学会総会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 新規バイオマテリアルS-PRGフィラーによるCandida albicans に及ぼす影響2014
- Author(s)
  阿部　和正，田村宗明，大屋　学，関　啓介，落合邦康
- Organizer
  第87回細菌学会総会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] Orally supplemented catechin has more beneficial effects to middle-aged rats2014
- Author(s)
  Cueno ME, Tamura M, Ochiai K
- Organizer
  第63回日本口腔衛生学会・総会
- Place of Presentation
  熊本市民会館（熊本県熊本市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 口腔細菌のウイルス感染症促進作用ーEBVおよびインフルエンザ感染に及ぼす影響ー2014
- Author(s)
  今井健一、神尾宜目、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀、東京
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔細菌はインフルエンザウィルス感染を促進する2014
- Author(s)
  神尾宜昌、今井健一、田村宗明、Ｍａｒｎｉ　Ｃｕｅｎｏ、齋藤夕子、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Ｐｅｒｉｏｄｏｎｔａｌ　ｂａｃｔｅｒｉａｌ　ｍｅｔａｂｏｌｉｔｅ　ｉｎｄｕｃｅｓ　ｒａｔ　ｂｌｏｏｄ　ａｐｏｐｔｏｔｉｃ　ａｎｄ　ｐｙｒｏｐｔｏｔｉｃ　ｃａｓｐａｓｅ　ａｃｔｉｖｉｔｉｅｓ2014
- Author(s)
  Ｍａｒｎｉ　Ｃｕｅｎｏ、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Ｓｔｒｕｃｔｕｒａｌ　ｓｉｇｎｉｆｉｃａｎｃｅ　ｏｆ　ｔｈｅ　ｂｅｔａ1ｋ396 residue found in the Porphyromonas gingivalis sialidase2014
- Author(s)
  齋藤夕子、Ｍａｒｎｉ　Ｃｕｅｎｏ、神尾宜昌、今井健一、田村宗明、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 新規バイオマテリアルS-PRGフィラーによるCandida albicansの付着と菌糸型変換に及ぼす影響2014
- Author(s)
  田村宗明、阿部和正、大屋　学、関　啓介、落合邦康
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 要介護高齢者に有効な口腔ケア法の開発2014
- Author(s)
  田村宗明、藤井　航、永田千里、坂口貴代美、大屋　学、落合邦康
- Organizer
  第97回日本細菌学会関東支部総会
- Place of Presentation
  東京ドームホテル（東京都文京区）
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] Ａ　ｐｏｓｓｉｂｌｅ　ｃｏｒｒｅｌａｔｉｏｎ　ｂｅｔｗｅｅｎ　ｏｒａｌ　ｂｕｔｙｒｉｃ　ａｃｉｄ　ａｎｄ　ａｇｉｎｇ2014
- Author(s)
  落合邦康、Ｍａｒｎｉ　Ｃｕｅｎｏ
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 食品用乳化剤は口腔細菌の増殖を抑制する2014
- Author(s)
  田村宗明，川戸貴行)，伊藤秀行，山田益巳，小口久雄，唐鎌史行，落合邦康，前野正夫
- Organizer
  第63回日本口腔衛生学会・総会
- Place of Presentation
  熊本市民会館（熊本県熊本市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] Ｈｅｍｉｎ濃度がＰｏｒｐｈｙｒｏｍｏｎａｓ　ｇｉｎｇｉｖａｌｉｓ増殖に及ぼす影響2014
- Author(s)
  大屋学、田村宗明、Ｍａｒｎｉ　Ｃｕｅｎｏ、落合邦康
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔ケアジェルによる口腔内カンジダ症および消化管移行抑制効果2013
- Author(s)
  田村宗明，大屋　学，阿部和正，落合邦康
- Organizer
  第55回歯科基礎医学会学術大会・総会
- Place of Presentation
  岡山コンベンションセンター（岡山)
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 歯周病原細菌代謝産物・酪酸の歯周組織に及ぼす影響と潜伏感染ウイルスの再活性化2013
- Author(s)
  落合邦康、今井健一、落合智子
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ国際会議場、千葉
- Year and Date
  2013-03-20
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 新規植物抽出成分による口腔微生物発育抑制効果2013
- Author(s)
  大屋　学，田村宗明，今井健一，落合邦康
- Organizer
  第55回歯科基礎医学会学術大会・総会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 食品用乳化剤の口腔細菌に対する静菌作用について2013
- Author(s)
  川戸貴行，田村宗明，伊藤秀行，山田益巳，落合邦康，前野正夫
- Organizer
  第19回日本摂食・嚥下リハビリテーション学会学術大会
- Place of Presentation
  川崎福祉大学（岡山）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] Orally-applied catechin increases heme levels in rat blood mitchondria2013
- Author(s)
  Cueno ME, Tamura M, Imai K, Ochiai K
- Organizer
  20th IAGG World Congress of Gerontology and Geriatrics
- Place of Presentation
  ソウル（韓国）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 歯周病を誘因とする全身疾患2013
- Author(s)
  落合邦康
- Organizer
  第17回日本腸内細菌学会
- Place of Presentation
  北里大学コンベンションホール,東京
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] EBV-歯周病原細菌間相互作用による潜伏感染EBVの再活性化と病態への関与2012
- Author(s)
  今井健一、落合邦康
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2012-11-14
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 抗菌ジェルによる要介護者口腔微生物数のコントロール効果2012
- Author(s)
  田村宗明、落合邦康
- Organizer
  第54回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  奥羽大学、福島
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 歯周病原細菌による潜伏感感染EBVの再活性化と病態への関与2012
- Author(s)
  落合邦康
- Organizer
  第55回日本歯周病学会秋季学術大会
- Place of Presentation
  つくば国際会議場、茨城
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Candida albicansに対する抗菌ジェルの病原性抑制効果と臨床応用2012
- Author(s)
  田村宗明、齋藤秀雄、今井健一、落合邦康
- Organizer
  第85回細菌学会総会
- Place of Presentation
  長崎ブリックホール・長崎県
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 新開発口腔ケア剤の口腔微生物に対する抗菌効果と臨床応用の可能性2011
- Author(s)
  田村宗明, 落合邦康
- Organizer
  第44回日本無菌生物ノートバイオロジー学会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] カテキンジェルの口腔微生物叢に及ぼす影響と要介護高齢者の口腔ケアへの応用2011
- Author(s)
  田村宗明、落合邦康
- Organizer
  第27回歯科医学を中心とした総合的な研究を推進する集い
- Place of Presentation
  日本歯科医師会館・東京都
- Year and Date
  2011-01-08
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] BIX01294はRAW264.7細胞のRANKL誘導破骨細胞分化を抑制する2011
- Author(s)
  津田啓方、今井健一、落合邦康、鈴木直人
- Organizer
  第53回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  長良川国際会議場、岐阜
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] Clinical application of gel-entrapped catechin against the oral microorganisms2011
- Author(s)
  Tamura M, Saito H, Ochiai K
- Organizer
  IUMS 2011 & 第84回細菌学会総会
- Place of Presentation
  札幌コンベンションセンター・北海道
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 歯周病原菌に対するカテキンジェルの抗菌効果(発表確定)2010
- Author(s)
  田村宗明, 落合邦康
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 高齢者ならびに要介護者の口腔細菌による難治性疾患予防法の開発2010
- Author(s)
  田村宗明, 落合邦康
- Organizer
  平成22年度日本大学学部連携研究推進シンポジウム
- Place of Presentation
  日大会館(東京都)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] カテキンジェルの口腔微生物に対する抗菌効果と臨床応用の可能性2010
- Author(s)
  田村宗明、落合邦康
- Organizer
  第16回日本摂食・嚥下リハビリテーション学会学術大会シンポジウム1摂食・嚥下リハビリテーションの新しい臨床を開く基礎研究
- Place of Presentation
  新潟朱鷺メッセ・新潟県
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] カテキンジェルの口腔微生物に対する抗菌効果と臨床応用の可能性2010
- Author(s)
  田村宗明, 落合邦康
- Organizer
  第16回日本摂食・嚥下リハビリテーション学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 歯周病原菌に対するカテキンジェルの抗菌効果2010
- Author(s)
  田村宗明, 落合邦康
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 口腔細菌叢に対するカテキンジェルの抗菌活性と口腔ケアへの応用について2009
- Author(s)
  田村宗明, 落合邦康
- Organizer
  第6回日本口腔ケア学会総会・学術大会
- Place of Presentation
  栃木総合文化センター(栃木県)
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] Antimicrobial action of gel entrapping catechin on oral microorganisms2009
- Author(s)
  田村宗明, 落合邦康
- Organizer
  87^<th> General Session & Exhibition of the IADR
- Place of Presentation
  Miami Beach Convention Center, Fla.USA
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] Antimicrobial action of GEC to evaluate the possible clinical application2009
- Author(s)
  田村宗明, 落合邦康
- Organizer
  2^<nd> Meeting of the IADR PAPF, 1^<st> Meeting of the IADR APR
- Place of Presentation
  Shangri-La Hotel, Wuhan, China
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21592664
[Presentation] 歯周病原性菌の産生する短鎖脂肪酸の作用と全身疾患2008
- Author(s)
  落合邦康
- Organizer
  第41回日本無菌生物ノートバイオロジー学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-01-25
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] 歯周病原性菌の産生する短鎖脂肪酸の作用と全身疾患2008
- Author(s)
  落合邦康
- Organizer
  第41回日本無菌生物ノートバイオロジー学会総会
- Place of Presentation
  神戸学院大学, 神戸市
- Year and Date
  2008-01-25
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] Effects of short-chain fatty acid on cell-cell communication in inhibiting butyric acid induced T-cell apoptosis2007
- Author(s)
  K. Ochiai
- Organizer
  13^<th> International Con-gress of Mucosal Immunology
- Place of Presentation
  品川プリンスホテル, 東京
- Year and Date
  2007-06-10
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] Effects of short-chain fatty acid on the expression of adhesion molecules in inhibiting butyric-acid induced T-cell apoptosis.2007
- Author(s)
  落合邦康
- Organizer
  第90回日本細菌学会関東支部会総会
- Place of Presentation
  東京
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] Effects of short-chain fatty acid on cell-cell communication in inhibiting butyric acid induced T-cell apoptosis.2007
- Author(s)
  K. Ochiai
- Organizer
  13th International Congress of Mucosal Immunology
- Place of Presentation
  東京
- Year and Date
  2007-06-10
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] 酪酸誘導T細胞apoptosis解除機構における短鎖脂肪酸のCD44発現に及ぼす影響2007
- Author(s)
  落合邦康
- Organizer
  第44回日本消化器免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-07-08
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] 歯周病原菌代謝産物・短鎖脂肪酸の粘膜・免疫組織に及ぼす影響-口腔細菌と腸内細菌研究の接点2006
- Author(s)
  落合邦康
- Organizer
  第48回歯科基礎医学総会
- Place of Presentation
  鶴見大学歯学部, 横浜市
- Year and Date
  2006-09-22
- Data Source
  KAKENHI-PROJECT-18592011
[Presentation] 抗菌ジェルによる要介護者口腔微生物数のコントロール効果
- Author(s)
  田村宗明，落合邦康
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  奥羽大学（福島県）
- Data Source
  KAKENHI-PROJECT-24593168
[Presentation] 新たな視点から歯周病原菌に対するリスクマネージメントを考える-歯周病研究における嫌気性菌代謝産物の意義-
- Author(s)
  落合邦康
- Organizer
  第５５回日本歯周病学会学術大会
- Place of Presentation
  つくば国際会議場 (茨城）
- Invited
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] P.gingivalis-produced butryic acid: effects on periodontal tissue and reactivation of latently infected viruses
- Author(s)
  落合邦康他
- Organizer
  First International Conference on Porphyromonas gingivalis and Related Bacterial Species.
- Place of Presentation
  長崎大学 (長崎)
- Invited
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 歯周病を誘因とする全身疾患
- Author(s)
  落合邦康
- Organizer
  第17回日本腸内細菌学会
- Place of Presentation
  北里大学コンベンションホール，東京
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 歯周病原細菌代謝産物・酪酸の歯周組織に及ぼす影響と潜伏感染ウイルスの再活性化
- Author(s)
  落合邦康他
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ (千葉)
- Invited
- Data Source
  KAKENHI-PROJECT-23592714
[Presentation] 口腔ケア剤による口腔ならびに全身疾患の発症予防
- Author(s)
  田村宗明，落合邦康
- Organizer
  第29回日本障害者歯科学会総会および学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-24593168

1. OCHIAI Tomoko (20130594)

# of Collaborated Projects: 11 results

# of Collaborated Products: 2 results
2. TAMURA Muneaki (30227293)

# of Collaborated Projects: 5 results

# of Collaborated Products: 73 results
3. SENPUKU Hidenobu (20250186)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. FUKUSHIMA Kazuo (20009327)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAGAWA Yumi (20348189)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. IMAI Kenichi (60381810)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
7. UEDA Kouichiro (80313518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. AMANO Shigeru (90167958)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KIKUCHI Kuniyoshi (10169823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TANAKA Hajime (40188321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. KURODA Kouichiro (70318450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. YAMADA Kiyoshi (30313076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TSUDA Hiromasa (60325470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. TAKEUCI Takeo (90171610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKESHITA Akira (70236454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. AMANO Osamu (60193025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SETO Shintaro (50383203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. IKEDA Tadashi (10050006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKADA Kazuko (20120496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HIRASAWA Masatomo (60095453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Cueno Marni (20569967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 追川哲雄 (90050020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. AIZAWA Shihoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 早川智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OCHIAI Kuniyasu 落合 邦康

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Effects of butyric acid producing bacteria on epigenetic gene regulation and systemic diseasesPrincipal Investigator

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Effects of Short-chain fatty acid on biofilm formation and bacterial invasionPrincipal Investigator

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Apoptosis induced by butyric acid modulates immunoresponses : Role of epitherial cells and fibroblasts in inhibiting butyric acid-induced T cell apoptosisPrincipal Investigator

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Effects of adhesion molecules and mechanism of gingival fibroblast rescue butyric acid-induced T-cell apoptosis.Principal Investigator

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Purification and molecular basis analysis of IL-1β like substance form periodontopathic bacteria.Principal Investigator

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A. a. 産生免疫抑制物質のT細胞ネットワークに及ぼす影響Principal Investigator

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OCHIAI Kuniyasu 落合邦康

[Book] 化学療法の領域　「序　口腔感染症の意味論－口腔内細菌による全身疾患と口腔ケア－」2011