SASAKI Hideki 佐々木秀樹

Researcher Number	50106316
External Links
Affiliation (based on the past Project Information) *help	2001: Yokohama City University, Dept of Pediatrics, assistant Professor, 医学部, 助教授 1999: Yokohama City University School of Medicine, Pediatrics, Associate Professor, 医学部・付属病院, 助教授 1997 – 1998: 横浜市立大学, 医学部・小児科, 助教授 1994 – 1998: Yokohama City University School of Medicine, Associate Professor, 医学部, 助教授 1996: YCKOHAMA CITY UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF PEDIATRICS, ASSISTANT PROFESSOR, 医学部・小児科学, 助教授 … More 1996: 横浜市立大学, 医学部・小児科学講座, 助教授 1991 – 1992: Yokohama City Univ. School of Medicine, Pediatrics, Associate Professor, 医学部, 助教授 1991: 横浜市立大学, 医学部・小児科学教室, 講師 1991: 横浜市立大学, 医学部・小児科学構座, 講師 1991: Yokohama City Univ. Med. Assistant Professer., 医学部・小児科学講座, 講師 1989 – 1991: 横浜市立大学, 医学部, 講師 1990: 横浜市立大学, 医学部小児科学講座, 講師 1988: Dept. of Pediatrics, Yokohama City University School of Medicine, 医学部小児科学教室, 助手 1987: 横浜市立大学, 医学部・小児科学教室, 助手 1986: Assay of hemopoietic stem cells and analysis of lymphocytes., 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Experimental pathology
Keywords	Principal Investigator p53 / TGF / thrombopoietin / stem cell / cell line / megakaryocyte / 造血幹細胞 / apoptosis / TGF-beta / hematopoietic stem cell … More / Hematopoletic progenitor / アポトーシス / TGF-β / cytokine / サイトカイン / 無蛋白培養 / 細胞株 / 巨核球 / Erythropoietin / Leukemia Inhibitory Factor / Stem Cell Factor / Interleukin 6 / Interleukin / Hemopoietic Stem Cells / CD_<34> / 免疫磁気ビ-ズ / 老化 / 幹細胞増殖因子 / 白血病阻害因子 / インタ-ロイキン6 / インタ-ロイキン3 / エリスロポイエチン / LIF / SCF / ILー6 / ILー3 / 血液幹細胞 / 細胞死 / 増殖機構 / 遺伝子導入 / myc遺伝子 … More Except Principal Investigator RT-PCR / 造血幹細胞 / PBSCT / Hemopoietic stem cells / acute leukemia / CD34 / CFU-GM / サイトカイン / 遺伝子導入 / CFU-S / thrombopoietin / chimeric RNA / TCR / MRD / PBSC / アポトーシス / FISH / MTG8 / ERG / FUS / TLS / HLF / E2A / AML1 / 放射線感受性 / CFUーS / 神経芽腫 / neuroblastoma / refractory acute leukemia / High-dose chemotherapy / 白血病 / BFU-E / 臍帯血 / 多能性造血幹細胞 / がん遺伝子 / transgenic mouse / spleen colony forming cells / リンパ球系前駆細胞 / 胸腺組織支持細胞 / 放射線抵抗性亜分画 / 細胞加齢 / 分裂寿命 / トランスジェニックマウス / 脾コロニー / Fibroblast / Aplastic anemia / Tリンパ球 / 骨髄Fibroblast / 再生不良性貧血 / SERUM-FREE CULTURE / HIGH PROLIFERATIVE POTENTIAL COLONY FORMING CELLS / HEMATOPOIETIC PROGENITORS / 増殖動態 / 幼若マウス / 加齢マウス / 増殖分化動態 / HPP-CFC / serum-free culture / high proliferative colony forming cells / hematopoietic progenitous / cell cycle / drug resistance / apoptosis / topoisomerase II / 細胞周期 / 薬剤耐性 / トポイソメラーゼ / IgH / AML / ALL / 遺伝子再構成 / 微少残存白血病 / 自家末梢血幹細胞移植 / FgH / hematopoietic progenitor cells / TGF-β / sytokine / p53-deficient mice / 骨髄造血前駆細胞 / TGFβ / P53欠失マウス / Spontaneous regression / Neuroblastoma / Cell lines / Small round celltumors / Translocation / Chromosome abnormality / 骨髄移植 / 小児白血病 / 小児がん疫学 / 小児肝がん / 小児腫瘍 / 自然退縮 / 神経芽種 / 細胞株 / 小円形細胞腫瘍 / 転座 / 染色体異常 / ALK / EVI1 / 末梢血幹細胞移植 / 微小残存病変 / AIK / EVI-1 / IFN-therapy / Liver Biopsy / Hepatitis C / Malignant diseases / HCV subtype / HCV-RNA / C型肝炎 / ウイルスコピー数 / ウイルスRNA / IFN / HCV / Geneticengineering / Complementarity-determiningregion III / Minimalresidual disease / Leukemia / PCR法 / 微少残存白血病細胞 / Bリンパ系白血病 / 遺伝子工学 / 免疫グロブリン超可変領域 / 微少残存病変 / Radiation sensitivity / spleen colonies. / CFU-S (colony forming Unit S) / 脾コロニ- / Nearoblastoma / GーCSF / CD34抗体 / 急性非リンパ性白血病 / CFUーmix / CFUーGM / 未梢血幹細胞移植(PBSCT) / CFU-Mix / BVA / Mitoxantrone / G-CSF / Myelomonocytic leukemia / Induction of differentiation / 無血清培養 / 分化誘導 / 白血症 / 造血幹細胞移植 / LTC-IC / HLA / 非血縁臍帯血移植 / 受容体サブユニット / IL-3受容体 / サイトカイン受容体 / 脾コロニー法 / サイトカイン・レセプター遺伝子 / 脾コロニ-法 / サイトカイン・レセプタ-遺伝子 / 夛能性造血幹細胞 Less

Research Projects
(21 results)
Co-Researchers
(18 People)

Control of hematopoietic progenitors and molecular mechanism Influencing cell cyclePrincipal Investigator
- Principal Investigator
  
  IKUTA Koichiro, 佐々木秀樹
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Intracellular damage caused by anti-cancer drugs and radiation, analysis of regulatory mechanism of apoptosis in topoisomerase mutant cells
- Principal Investigator
  
  FUNABIKI Tetsunori
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University School op Medicine
CLINICO-PATHOLOGICAL STUDY OF PEDIATRIC TUMORS
- Principal Investigator
  
  NAGASHIMA Yojl, MISUGI Kazuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Signal transduction mediated by hematopoietic factors and TGF-β in p53-deficient mice
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
Characterization of hematopoietic stem cells in p53-deficient micePrincipal Investigator
- Principal Investigator
  
  SASAKI Hideki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  YOKOHAMA CITY UNIVERSITY
Minimal residual leukemia in autologous peripheral blood stem cell transplantation
- Principal Investigator
  
  IKUTA Koichiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  YOKOHAMA CITY UNIVERSITY
臍帯血造血幹細胞移植に関する基礎的研究
- Principal Investigator
  
  NATSUYAMA Shusuke
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Detection and analysis of the function of fusion gene in childhood leukemia with chromosomal translocation.
- Principal Investigator
  
  FUNABIKI Tetsunori
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
myc遺伝子導入造血幹細胞における増殖と細胞死シグナルの解析Principal Investigator
- Principal Investigator
  
  佐々木秀樹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
造血幹細胞へのサイトカイン受容体遺伝子導入による造血調節因子作用機構に関する研究
- Principal Investigator
  
  井上達
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Studies on regulatory mechanisms of megakaryocytepoiesis using the cell line grown in protein-free culture.Principal Investigator
- Principal Investigator
  
  SASAKI Hideki
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University School of Medicine
Basic and Clinical Research for Hepatitis C Virus Infection with Malignant Disease in Childhood
- Principal Investigator
  
  IKUTA Koichiro
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
多能性造血幹細胞への遺伝子導入とその機能発現
- Principal Investigator
  
  井上達
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Detectionof Minimal Residual Disease in Childhood Leukemia by Polymerase Chain Reaction
- Principal Investigator
  
  MATSUYAMA Shusuke
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
多能性造血幹細胞への遺伝子導入と、その機能発現
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Basic and Clinical Research for Peripheral Blood Stem Cell Transplantation
- Principal Investigator
  
  IKUTA Koichiro
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Study on a fraction with relative radioresistency from murine pluripotent hemopoietic stem cells.
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yokohama City University, Sohool of Medicine
Studies on the Action of the Induction of Differentiation in Leukemia Cells by G-CSF and Mitoxatoxantrone
- Principal Investigator
  
  NATSUYAMA Shusuke
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
The mechanisms of proliferation and differentiation of hematopoietic multipotent stem cells.Principal Investigator
- Principal Investigator
  
  SASAKI Hideki
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University, School of Medicine
Study on proliferation and Differentiation of pluripotent hemopoietic stem cells (CFU-S).
- Principal Investigator
  
  INOUE Tohru M.D.
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Department of Pathology, Yokohama City University School of Medicine
Researches on Pathogenesis of Aplastic Anemia
- Principal Investigator
  
  MATSUYAMA Shusuke
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University School of Medicine

1. IKUTA Koichiro (80159590)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
2. INOUE Tohru (50100110)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. NATSUYAMA Shusuke (20045983)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
4. FUNABIKI Tetsunori (20264616)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
5. HIRABAYASHI Yoko (30291115)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 木内吉寛 (80012764)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 横田崇 (50134622)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. NAGASHIMA Yojl (10217995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MISUGI Kazuki (50106332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 甲斐純夫 (10233644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SUMITA Hiroko (10254202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYAGI Yohei (00254194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKAGI Atsuya (00179417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIROSE Akihiko (90228833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 渡辺真一郎 (00240490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 梅村隆志 (50185071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAJIGAYA Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 関口晴之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAKI Hideki 佐々木 秀樹

Research Projects

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Control of hematopoietic progenitors and molecular mechanism Influencing cell cyclePrincipal Investigator

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Characterization of hematopoietic stem cells in p53-deficient micePrincipal Investigator

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myc遺伝子導入造血幹細胞における増殖と細胞死シグナルの解析Principal Investigator

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Studies on regulatory mechanisms of megakaryocytepoiesis using the cell line grown in protein-free culture.Principal Investigator

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SASAKI Hideki 佐々木秀樹