Yamaguchi Teruhide 山口照英

… Alternative Names

YAMAGUCHI Teruhide 山口照英

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Researcher Number	50111117
Other IDs
External Links
Affiliation (Current)	2025: 日本薬科大学, 薬学部, 客員教授 2025: 国立医薬品食品衛生研究所, 衛生微生物部, 客員研究員
Affiliation (based on the past Project Information) *help	2006: National Institute of Health sciences, Division of Biological Chemistry and Biological, Head 2003 – 2005: 国立医薬品食品衛生研究所, 遺伝子細胞医薬部, 部長
Review Section/Research Field	Principal Investigator Biological pharmacy Except Principal Investigator Medical pharmacy
Keywords	Principal Investigator G-CSF / p70S6K / PKCiota / aPKC / HL-60 cell / unequal division / neutrophilic differentiation / PKCι / HL-60細胞 / 不等分裂 / 好中球分化 … More Except Principal Investigator … More magnetofection / adenovirus vector / gene therapy / ポリエチレンイミン / ウイルス検出 / 感染性PCR / 増殖性アデノウイルス / アデノウイルスベクター / 遺伝子治療 / virus detection method / vector sheddine / polyethyleneimineviral / infectivity PCR / replication-competent adenovirus / ウイルス・ベクター排出 / polyethyleneimine / virus detection / infectivity-PCR / repication-competent adenovirus / replication-competent retrovirus / retrovirus vector / ガラスビーズ / ガラスビーズ法 / ポリエチレンイミン磁気ビーズ / 増殖性レトロウイルス / レトロウイルスベクター Less

Development of sensitive detection methods for viral shedding of adenovirus vector and replication-competent adenovirus
- Principal Investigator
  
  UCHIDA Eriko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
The role of un-equal division on regulation of neutrophilic differentiation and the participation of G-CSFPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Teruhide
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
Development of rapid and high sensitivity detection methods for replication-competent viruses contaminated in viral vector products for gene therapy
- Principal Investigator
  
  UCHIDA Eriko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences

All 2007 2005 2004 2003 Other

All Journal Article

[Journal Article] Regulatory Aspects of Oncolytic Virus Products2007
- Author(s)
  Teruhide Yamaguchi, Eriko Uchida
- Journal Title
  
  Current Cancer Drug Targets 7
  
  Pages: 203-208
- Data Source
  KAKENHI-PROJECT-17590141
[Journal Article] Optimization of the virus concentration method using polyethyleneimine-conjugated magnetic beads and its application to the detection of human hepatitis A,B and C viruses2007
- Author(s)
  Eriko Uchida, Mieko Kogi, Tadashi Oshizawa, Koei Satoh, Akiko Iwata, Mitsuhiro Murata, Mikio Hikata, Teruhide Yamaguchi
- Journal Title
  
  Journal of Virological Methods 143
  
  Pages: 95-103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590141
[Journal Article] Regulatory Aspects of Oncolytic Virus Products2007
- Author(s)
  Teruhide Yamaguchi, Eriko Uchida
- Journal Title
  
  Current Cancer Drvg Targets 7
  
  Pages: 203-208
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590141
[Journal Article] 日米EU医薬品規制調和国際会議遺伝子治療専門家会議の活動と遺伝子治療薬の規制における国際動向2007
- Author(s)
  山口照英, 内田恵理子
- Journal Title
  
  Drug Delivery System 22-6
  
  Pages: 651-659
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590141
[Journal Article] 遺伝子治療薬及び細胞治療薬のウイルス安全性確保2007
- Author(s)
  内田恵理子, 石井(渡部) 明子, 山口照英
- Journal Title
  
  臨床とウイルス 35
  
  Pages: 278-290
- NAID
  10019820271
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590141
[Journal Article] Regulatory Aspects of Oncolytic Virus Products2007
- Author(s)
  Yamaguchi, T., Uchida, E.
- Journal Title
  
  Current Cancer Drug Targets 7
  
  Pages: 203-208
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590141
[Journal Article] Suppression of proliferation of poliovirus and porcine parvovirus by novel phenoxazine, 2-amino-4, 4a-dihydro-4a-7-dimethyl-3H-phenoxazine and 3-amino-1, 4a- dihydro-4a-8-dimethyl-2H-phenoxazine-2-one.2005
- Author(s)
  Iwata, A., Sato, K., Yamaguchi, T., Yoshiake, N., Tomoda, A
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 905-907
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Approaches to Improving the kinetics of adnovirus-delivered genes and gene products.2005
- Author(s)
  Xu, Z., Mizuguchi, H., Sakurai, F., Koizumi, N., Hosono, T., Kawabata, K., Watanabe, Y., Yamaguchi, T., Hayakawa, T.
- Journal Title
  
  Adv Drug Del Rev. 57
  
  Pages: 781-802
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] HX531, RXR antagonist inhibited the 9-cis retinoic acid-induced binding with cofactor.2005
- Author(s)
  Kanayasu-Toyoda, T., Fujino, T., Oshizawa, T., Suzuki, T., Nishimaki-Mogami, T., Sato, Y., Sawada, J., Inoue, K., Shudo, K., Yamaguchi, T.
- Journal Title
  
  J Steroid.Biochem.Molec.Biol. 94
  
  Pages: 305-309
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Two-dimensional electrophoresis of disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis.2005
- Author(s)
  Yamamoto, Y, Akita, Y, Tai, S., Fukasaku, S., Yamaguchi, T., Oshizawa, T., Yamaoka, K., Shimamura, M, Hazato, T.
- Journal Title
  
  J.Elecctrophoresis 49
  
  Pages: 23-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Two-dimensional electrophoresisof disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis2005
- Author(s)
  Yamamoto, Y., Akita, Y., Tai, S., Fukasaku, S., Yamaguchi, T., Oshizawa, T., Yamaoka, K., Shimamura, M., Hazato, T.
- Journal Title
  
  J.Elecctrophoresis 49
  
  Pages: 23-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Approaches to Improving the kinetics of adnovirus-delivered genes and gene products.2005
- Author(s)
  Xu, Z., Mizuguchi, H., Sakurai, F., Koizumi, N., Hosono, T., Kawabata, K, Watanabe, Y., Yamaguchi, T., Hayakawa, T.
- Journal Title
  
  Adv Drug Deliv Rev 57
  
  Pages: 781-802
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] HX531,RXR antagonist inhibited the 9-cis retinoic acid-induced binding with cofactor.2005
- Author(s)
  Kanayasu-Toyoda, T., Fujino, T., Oshizawa, T., Suzuki, T., Nishimaki-Mogami, T., Sato, Y., Sawada, J., Inoue, K., Shudo, K., Yamaguchi, T.
- Journal Title
  
  J.Steroid Biochem Mol. 94
  
  Pages: 303-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Suppression of proliferation of poliovirus and porcine parvovirus by novel phenoxazine, 2-amino-4,4a-dihydro-4a-7-dimethyl-3H-phenoxazine and 3-amino-1,4a-dihydro-4a-8-dimethyl-2H-phenoxazine-2-one.2005
- Author(s)
  Iwata, A.Sato, K., Yamaguchi, T., Yoshiake, N., Tomoda, A
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 905-907
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] An improved method for detection of replication competent retrovirus in retrovirus vector products2004
- Author(s)
  Uchida E., Sato K., Iwata A., Ishii-Watabe A., Mizuguchi H., Hikata M., Murata M., Yamaguchi T., Hayakawa T.
- Journal Title
  
  Biologicals. 32
  
  Pages: 139-146
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library.2004
- Author(s)
  Kusui K., Sasaki H., Adachi R., Matsui S., Yamamoto K., Yamaguchi T., Kasahara T., Suzuki K.
- Journal Title
  
  Bio Mol.Cell.Biochem 262
  
  Pages: 187-193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] An improved method for detection of replication competent retrovirus in retrovirus vector products.2004
- Author(s)
  Uchida E, Sato K., Iwata A., Ishii-Watabe A., Mizuguchi H., Hikata M., Murata M., Yamaguchi T., Hayakawa T.
- Journal Title
  
  Biologicals 32
  
  Pages: 139-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library.2004
- Author(s)
  Kusui K., Sasaki H., Adachi R., Matsui S., Yamamoto K., Yamaguchi T., Kasahara T., Suzuki K.
- Journal Title
  
  Mol.Cell.Biochem. 262
  
  Pages: 187-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Adenovirus vector-mediated doxycycline-inducible RNA interference.2004
- Author(s)
  Hosono T., Mizuguchi H., Katayama K., Xu Z.L., Sakurai F., Ishii-Watabe A., Kawabata K., Yamaguchi T., Nakagawa S., Mayumi T., Hayakawa T.
- Journal Title
  
  Hum.Gene Ther. 15
  
  Pages: 813-819
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] An improved method for detection of replication competent retrovirus in retrovirus vector products2004
- Author(s)
  Uchida E, Sato K., Iwata A., Ishii-Watabe A., Mizuguchi H., Hikata M., Murata M., Yamaguchi T., Hayakawa T.
- Journal Title
  
  Biologicals. 32
  
  Pages: 139-146
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] An improved method for detection of replication competent retrovirus in retrovirus vector products2004
- Author(s)
  Uchida E, Sato K., Iwata A., Ishii-Watabe A., Mizuguchi H., Hikata M., Murata M., Yamaguchi T., Hayakawa T.
- Journal Title
  
  Biologicals 32
  
  Pages: 139-146
- Data Source
  KAKENHI-PROJECT-15590150
[Journal Article] The role of c-Myc on granulocyte colony-stimulating factor-dependent neutrophilic proliferation and differentiation of HL-60 cells.2003
- Author(s)
  Kanayasu-Toyoda T, Yamaguchi T, Oshizawa T, Uchida E, Hayakawa T
- Journal Title
  
  Biochem.Pharmacol. 66
  
  Pages: 133-140
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Virus Concentration Using Polyethyleneimine- conjugated Magnetic Beads for Improvement of Sensitivity in Nucleic Acid Amplification Tests.2003
- Author(s)
  Satoh, K., Iwata, A., Murata, M., Hikata, M., Hayakawa, T., Yamaguchi, T.
- Journal Title
  
  J Virol, Methods 114
  
  Pages: 11-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Virus Concentration Using Polyethyleneimine-conjugated Magnetic Beads for Improvement of Sensitivity in Nucleic Acid Amplification Tests.2003
- Author(s)
  Satoh, K., Iwata, A., Murata, M., Hikata, M., Hayakawa, T., Yamaguchi, T.
- Journal Title
  
  J Virol, Methods 114
  
  Pages: 11-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Possible Involvement of Optimally Phosphorylated L-plastin in Activation of Superoxide Generating NADPH Oxidase.2003
- Author(s)
  Oshizawa, T., Yamaguchi1, T, Suzuki, K., Yamamoto, Y., Hayakawa, T.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 827-834
- NAID
  50000393691
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Reduction of natural adenovirus tropism to mice liver by fiber-shaft exchange in combination with both CAR- and v integrin-binding ablation.2003
- Author(s)
  Koizumi, N., Mizuguchi, H., Sakurai, F, Yamaguchi, T., Watanabe, Y., Hayakawa, T.
- Journal Title
  
  J Virol. 77
  
  Pages: 13062-13072
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Reduction of natural adenovirus tropism to mice liver by fiber-shaft exchange in combination with both CAR- and v integrin-binding ablation.2003
- Author(s)
  Koizumi, N., Mizuguchi, H., Sakurai, F., Yamaguchi, T., Watanabe, Y., Hayakawa, T.
- Journal Title
  
  J Virol. 77
  
  Pages: 13062-13072
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] CD31 (PECAM-1)-bright cells derived from AC133-positive cells in human peripheral blood as endothelial-precursor cells.2003
- Author(s)
  Kanayasu-Toyoda T, Yamaguchi T, Oshizawa T, Hayakawa T
- Journal Title
  
  J Cell.Physiol. 195
  
  Pages: 119-129
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Characterization of in vitro and in vivo gene transfer properties of adenovirus serotype 35 vector.2003
- Author(s)
  Sakurai F., Mizuguchi H., Yamaguchi T., Hayakawa T.
- Journal Title
  
  Mol.Ther. 8
  
  Pages: 813-821
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] 生物薬品のウイルス安全性を目的とした核酸増幅検査(NAT)のフィージビリティースタディー2003
- Author(s)
  山口照英, 内田恵理子
- Journal Title
  
  医薬品研究 34
  
  Pages: 763-769
- Data Source
  KAKENHI-PROJECT-15590150
[Journal Article] Detection of Replication-Competent Adenoviruses Spiked into Recombinant Adenovirus Vector Products by Infectivity-PCR2003
- Author(s)
  Ishii-Watabe A., Uchida E., Iwata A., Nagata R., Satoh K., Fan K., Murata M., Mizuguchi H., Kawasaki N., kawanishi T., Yamaguchi T., Hayakawa T.
- Journal Title
  
  Molecular Therapy 8
  
  Pages: 1009-1016
- Data Source
  KAKENHI-PROJECT-15590150
[Journal Article] Possible Involvement of Optimally Phosphorylated L-plastin in Activation of Superoxide Generating NADPH Oxidase.2003
- Author(s)
  Oshizawa, T., Yamaguchi, T., Suzuki, K., Yamamoto, Y., Hayakawa, T.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 827-834
- NAID
  50000393691
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Suppression of proliferation of poliovirus and porcine, parvovirus by novel phenoxazine, 2-amino-4,4a-dihydro-4a-7-dimethyl-3H-phenoxazine and 3-amino-1,4a-dihydro-4a-8-dimethyl-2H-phenoxazine-2-one.
- Author(s)
  Iwata, A., Sato, K., Yamaguchi, T., Yoshiake, N., Tomoda, A
- Journal Title
  
  Biol.Pharm.Bull. (In press)
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] HX531, RXR antagonist inhibited the 9-cis retinoic acid-induced binding with cofactor.
- Author(s)
  Kanayasu-Toyoda, T., Fujino, T., Oshizawa, T., Suzuki, T., Nishimaki-Mogami T., Sato, Y., Sawada, J., Inoue K., Shudo, K., Yamaguchi, T.
- Journal Title
  
  J Steroid Biochem.Molec.Biol. (in press)
- Data Source
  KAKENHI-PROJECT-15590091
[Journal Article] Approaches to Improving the kinetics of adnovirus-delivered genes and gene products.
- Author(s)
  Xu, Z., Mizuguchi, H., Sakurai, F., Koizumi, N., Hosono, T., Kawabata, K., Watanabe, Y., Yamaguchi, T., Hayakawa, T.
- Journal Title
  
  Adv Drug Del Rev. (In press)
- Data Source
  KAKENHI-PROJECT-15590091

1. UCHIDA Eriko (80176685)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. NAGATA Ryuji (20370942)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. ISHII Akiko (50291117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Yamaguchi Teruhide 山口 照英

YAMAGUCHI Teruhide 山口 照英

Research Projects

Research Products

Co-Researchers

Development of sensitive detection methods for viral shedding of adenovirus vector and replication-competent adenovirus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of un-equal division on regulation of neutrophilic differentiation and the participation of G-CSFPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of rapid and high sensitivity detection methods for replication-competent viruses contaminated in viral vector products for gene therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Regulatory Aspects of Oncolytic Virus Products2007

Author(s)

Journal Title

Data Source

[Journal Article] Optimization of the virus concentration method using polyethyleneimine-conjugated magnetic beads and its application to the detection of human hepatitis A,B and C viruses2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Regulatory Aspects of Oncolytic Virus Products2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] 日米EU医薬品規制調和国際会議遺伝子治療専門家会議の活動と遺伝子治療薬の規制における国際動向2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] 遺伝子治療薬及び細胞治療薬のウイルス安全性確保2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Regulatory Aspects of Oncolytic Virus Products2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Suppression of proliferation of poliovirus and porcine parvovirus by novel phenoxazine, 2-amino-4, 4a-dihydro-4a-7-dimethyl-3H-phenoxazine and 3-amino-1, 4a- dihydro-4a-8-dimethyl-2H-phenoxazine-2-one.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Approaches to Improving the kinetics of adnovirus-delivered genes and gene products.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] HX531, RXR antagonist inhibited the 9-cis retinoic acid-induced binding with cofactor.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Two-dimensional electrophoresis of disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Two-dimensional electrophoresisof disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Approaches to Improving the kinetics of adnovirus-delivered genes and gene products.2005

Author(s)

Yamaguchi Teruhide 山口照英

YAMAGUCHI Teruhide 山口照英