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HIMENO Kunisuke  姫野 國祐

ORCIDConnect your ORCID iD *help
… Alternative Names

姫野 国祐  ヒメノ クニスケ

HIMENO Kunisuki  姫野 国祐

姫野 国裕

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Researcher Number 50112339
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2006 – 2008: 九州大学, 医学研究院, 教授
2007: Kyushu University, 大学院・医学研究院, 教授
2005: Kyushu University, Faculty of Medicine, Professor, 大学院医学研究院, 教授
2001 – 2005: 九州大学, 大学院・医学研究院, 教授
2001: 九州大学, 医学部, 教授 … More
1991 – 2000: 徳島大学, 医学部, 教授
1995 – 1996: 徳島大学, 医学部・寄生虫学講座, 教授
1988 – 1989: 徳島大学, 医学部, 教授
1987: 九州大学, 生体防御医学研究所, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / 寄生虫学(含医用動物学) / Parasitology (including Sanitary zoology) / 寄生虫学(含医用動物学) / Dermatology
Except Principal Investigator
寄生虫学(含医用動物学) / 内分泌・代謝学 / General surgery / Functional basic dentistry / Orthopaedic surgery … More / Virology / Bacteriology (including Mycology) / Parasitology (including Sanitary zoology) / Dermatology / Immunology Less
Keywords
Principal Investigator
熱ショック蛋白質 / 病原性 / トキソプラズマ / DNAワクチン / 原虫感染免疫 / HSP90 / CD8^+T細胞 / 原虫感染 / HSP65 / マラリア … More / γδT細胞 / PA28ノックアウトマウス / プロテアソーム阻害剤 / ユビキチン融合遺伝子 / マラリア原虫 / 感染防御 / リーシュマニア / 細胞内寄生原虫 / フュージョンDNA / ユビキチン遺伝子 / TRP-2 / メラノーマ / Heat shock protein / ユビキチンプロテアソーム / SAG-1 / ユビキチンプロテアソーム系 / 分子シャペロン / 原虫 / proteasome inhibitor / proteasome KO mice / ubiquitin-proteasome / ubiquitin / gene gun / DNA vaccine / intracellular protozoa / プロテアソームKOマウス / 遺伝子銃 / 細胞内寄生病原虫 / Plasmodium yoelii / HSP 90 / Heat shock proteins / NKT細胞 / low and high virulence / γδ型T細胞 / 弱毒株と強毒株 / Protective immunity / アポトーシス / T細胞 / αβT細胞 / エスケープ機構 / CD84T cell / CD8^+ T cell / host-defense / opportunistic HSP expression / evasion of protozoa / mouse malaria / NK細胞 / αβ型T細胞 / 宿主防御 / 日和見的HSP発現 / 原虫エスケープ / Resistace to infection / Malaria / Protozoa infection / Resistance to infection / delta T cells / gamma / Protection to protozoa infection / Toxoplasma gondii / マクロファージ / HSP / 細胞性寄生性 / 感染抵抗性 / 原虫感染防御 / gammadelta T cell / Virulence / Leishmania / Toxoplasma / Protozoan infection / 防御免疫 / host macrophage / gamma delta T cells / escape / protective immunity / protozoa / heat shock protein / 宿主マクロファージ / エスケープ / Toxoplasma infection / Cytokine / CD4^+ T deficient rat / 日和見感染症 / T細胞系幹抵抗異常 / ヌ-ドラットへの胎児胸腺移植 / インタ-ロイキン2 / 免疫不全症 / CD4^+ヘルパ-T細胞欠損ラット / CD4^十T欠損ラット / 感染防御能 / トキソプラズマ感染 / サイトカイン / CD4^+欠損ラット / 3LL肺癌 / 抗腫瘍免疫 / MUT1遺伝子 / 3LL 肺癌 / DNA ワクチン / 抗腫傷免疫 / フージョンDNA / MHCクラスI / 細胞内寄生病原体 / 融合ワクチンベクター / 遺伝子治療 / 感染制御 / コンビネーションDNAワクチン / IL-12 / サイトカイン遺伝子治療 / HSP70 / 抗腫腸免疫 / サイトカイン遺伝子 / Renca腫腸 / HPS90 / リーシュマニア症 / Th2 / Th1 / 抗原プロセッシング / カテプシン / Tリンパ球 / カテプシンB / システインプロテアーゼ / 熱シッョク蛋白質 … More
Except Principal Investigator
IL-10 / サイトカイン / 熱ショック蛋白質 / 遺伝子銃 / DNAワクチン / HLA / 遺伝子 / MHC-I / Nef / Vpr / Vif / Env / Gag / HIV / Toxoplasma gondii / HSP65 / 感染防御 / paracrine secretion / lymphocytes / cytokine / IDDM / pancreatic islet B-cell / gene therapy / リンパ球 / I型糖尿病 / 糖尿病 / 遺伝子治療 / FK506 / ユビキチン / アイソザイム / 病型 / 中南米 / Trypanosoma cruzi / シャーガス病 / マラリア / Thymus-grafted nude mice / bone marrow chimera / Thymus / T cell differentiation / T cell receptor / T cells / 長期培養骨髄細胞 / 骨髄キメラマウス / T細胞抗原レセプター(α,β,γ,δ鎖)遺伝子 / 胸腺移植ヌードマウス / 放射線照射骨髄移植キメラマウス / T細胞抗原レセプター / 胸腺移植ヌ-ドマウス / 放射線照射骨髄移植マウス / T細胞レセプタ- / 胸腺 / トレランス / T細胞分化 / Electrocardiogram / Genetic exchange / Mega colon / Cardiac Chagas / Heterogeneity / Susceptibility / Chagas Disease / 分離培養原虫株 / 心臓シャーガス / 南アメリカ / 中央アメリカ / 巨大結腸症 / ラテンアメリカ / 遺伝子多型 / 二次元電気泳動 / 種内変異 / 疾患感受性 / プロテオーム / 感染性 / 遺伝多型 / クルーズトリパノソーマ / 遺伝子交換 / 慢性シャーガス病 / 多様性 / クルーストリパノソーマ / host-genetic factors in malaria severity / malaria diagnosis / Phage-display method / Thailand-Myanmar Border / falciparum malaria / Hainan Island / Thailand / トロンボキサン / プロスタグランデイン / 遺伝的素因 / マラリア診断 / マラリア重症化 / 重症化の遺伝的素因 / マラリア臨床診断 / ファージ・ディスプレイ法 / タイ・ミャンマー国境 / 熱帯熱マラリア / 海南島 / タイ国 / gene gun / cartilage / gene / 軟骨細胞 / 軟骨 / Apoptosis / キャプシド / アポトーシス / anti-apoptosis action / ischemic-reperfusion injury / heat shock protein / immuno-tolerance / liver transplantation / small bowel transplantation / ドナー抗原 / リンパ球混合培養試験 / GVHD / ドナー脾細胞 / microchimerism / 免疫寛容 / 免疫寛客 / 抗アポトシス作用 / 肝虚血再潅流障害 / 熱シロック蛋白質 / 免疫免容 / 肝移植 / 小腸移植 / SCID mouse / Protective immunity / gammadelta T cells / Heat Shock Potein / SCIDマウス / γδ型T細胞 / Host defense / Infection / Macrophages / Protozoa / Bacteria / Intracellular parasitism / 感染 / マクロファージ / 原虫 / 細菌 / 細胞内寄生 / diabetes / トランスジェニックマウス / 膵ランゲルハンス島 / IFNγ / deabetes / レトロウィルスベクター / Tリンパ球 / インターフェロンγ / インターロイキン10 / 自己免疫疾患 / 膵ラ島B細胞 / 免疫制御体 / ドナー細胞移植前投与 / 移植臓器拒絶反応 / Drung-induced Tolerance / リンパ組織選択的X線照射 / OKT3 / 杭イディオタイプ抗体 / donor特異的術前輸血 / ナチュラルキラー様細胞傷害活性 / 老齢マウス / 新生児胸腺摘出マウス / ヌードマウス / β鎖遺伝子 / T細胞抗原レセプターγ / 肝臓内型 / 赤血球内型 / ユビキチンプロテアソーム系 / マラリア強毒株 / CD8^+T細胞 / プロテアソーム / TRP2遺伝子 / 抗腫瘍免疫 / ユビキチンプロテアソーム / メラノーマ / colon26 / AQP-1 / 血管新生因子 / ubiquitin-proteasome system / CTL / 悪性メラノーマ / 世界寄生虫学会 / Federation of Asian Parasitologists / アジア / 寄生虫学 / 寄生虫学者 / アジア寄生虫学者連盟 / 熱ショック蛋白質90 / 遺伝子解析 / H_2O_2 / NO / HSP 90 / マラリア原虫 / 遺伝的多型 / 後期適応免疫 / 早期誘導反応 / 自然免疫 / ノックアウトマウス / 感染免疫 / MAP-1 / SERA Less
  • Research Projects

    (47 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (67 People)
  •  DNA vaccine targeting both liver and blood stage of virulent strain PlasmodiumPrincipal Investigator

    • Principal Investigator
      HAMANO Shinjiro, 姫野 国祐
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Kyushu University
  •  ユピキチンプロテアソーム系の応用による2段階肺癌遺伝子ワクチンPrincipal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  ユビキチンプロテアソーム系の応用によるメラノーマに対する2段階DNAワクチン

    • Principal Investigator
      古江 増隆
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Kyushu University
  •  Development of DNA vaccine against intracellular protozoa bored on ubiquitin-proteasome systemPrincipal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      KYUSHU UNIVERSITY
  •  ユビキチンプロテアソーム系の応用による細胞内寄生原虫に対するDNAワクチンの開発Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  ユビキチンプロテアソームシステムの応用による癌遺伝子ワクチンの開発研究Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  ユビキチンプロテアソーム系の応用によるメラノーマに対するDNAワクチン法の開発Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Kyushu University
  •  Development of DNA vaccine against intracellular protozoa bored on ubiquitin-proteasome systemPrincipal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      KYUSHU UNIVERSITY
  •  免疫調節遺伝子とのフュージョンDNAワクチンによる細胞内寄生原虫感染制御の新戦略Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  メラノーマに対するフュージョン及びコンビネーションDNAワクチン療法の新規開発Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  免疫調節遺伝子とのフュージョンDNAワクチンによる細胞内寄生原虫感染制御の新戦略Principal Investigator

    • Principal Investigator
      姫野 国祐
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  メラノーマに対するフュージョン及びコンビネーションDNAワクチン療法の新規開発Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Pathogenic factors for the development of chronic Chagas disease in Latin America

    • Principal Investigator
      HIRAYAMA Kenji
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Nagasaki University
      Saitama Medical University
  •  マラリア原虫の病原性に係わる熱ショック蛋白質の機能Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  マラリア原虫の病原性(エスケープ)に係わる分子シャペロンHSP90の機能Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  クルーズ・トリパノソーマの遺伝的多型性と病原性に関する研究

    • Principal Investigator
      多田 功
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Kyushu University
  •  マラリアの病原性に関与する熱ショック蛋白質90の遺伝子解析

    • Principal Investigator
      前川 洋一, 高島 美和
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokushima
  •  アジア寄生虫学者連盟の設立企画

    • Principal Investigator
      多田 功
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Kyushu University
  •  Basic studies on strategy against HIV

    • Principal Investigator
      ADACHI Akio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Virology
    • Research Institution
      The University of Tokushima
  •  Direct Gene Transfer Into Articular Cartilage By Gene Gun

    • Principal Investigator
      UMEHARA Takashi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokushima
  •  Complicated falciparum malaria

    • Principal Investigator
      AIKAWA Masamichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokai University
  •  マラリア原虫の病原性に係わる熱ショック蛋白質の機能Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  Th分化を調節する抗原提示細胞内酵素・カテプシンBPrincipal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  分子シャペロンHSP90のマラリア原虫の病原性における機能の解析Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  感染免疫の分子基盤の新展開

    • Principal Investigator
      YOSHIKAI Yasunobu
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Nagoya University
  •  Role of Heat Shock Protein against Protozoan InfectionPrincipal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokushima University
  •  Clarification of evasion mechanisms of protozoa on the basis of expression pattern of heat shock proteins in parasites and hosts.Principal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokushima University
  •  マラリア原虫感染における原虫および宿主の熱ショック蛋白質の機能Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  分子シャペロンHSP65による原虫感染宿主細胞のアポトーシスの抑制と感染防御Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  遺伝子鏡を用いたマラリア感染に対するDNAワクチネーションの基礎的研究

    • Principal Investigator
      酒井 敲 (酒井 徹)
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokushima
  •  ANALYSIS OF MICROCHIMERISM BY TRANSPLANT PRETREATMENT OF ALLOANTIGEN OR XENOANTIGEN IN LIVER AND SMALL BOWEL TRANSPLANTATION

    • Principal Investigator
      TASHIRO Seiki
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      THE UNIVERSITY OF TOKUSHIMA
  •  マラリア原虫の病原性に係わる分子としての熱ショック蛋白質の機能Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  システインプロテアーゼによるリーシュマニア感染T細胞機能的分化の新しい制御理論Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokushima
  •  Role of Heat Shock Protein against Protozoan InfectionPrincipal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      University of Tokushima
  •  Basic Research on the escape mechanism of intracellular parasites and the host response in infection

    • Principal Investigator
      MITSUYAMA Masao
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Niigata University
  •  EXPRESSION OF HEAT SHOCK PROTEIN WHICH CONTROLS THE INFECTIVITY OF TOXOPLASMA AND HOST RESISTANCE AGAINST INFECTION

    • Principal Investigator
      NAGASAWA Hideyuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE
  •  原虫の毒力の差による熱ショック蛋白質発現の相違と原虫エスケープ・宿主防御機構Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Role of HSP65 in host protection against intracellular protozoan infection.Principal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokushima University
  •  原虫の毒力の差による熱ショック蛋白質発現の相違と原虫エスケープ・宿主防御機構Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  トキソプラズマ感染防御に係わるT細胞による宿主MΦへのHSP65発現機序の解明Principal Investigator

    • Principal Investigator
      姫野 國祐
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokushima
  •  Analysis of Immunological Destruction Mechanism of Pancreatic Islet B Cells Using a Transgenic Mouse Model

    • Principal Investigator
      ITAKURA Mitsuo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokushima
  •  Role of heat shock protein expressed on protozoa and hostsPrincipal Investigator

    • Principal Investigator
      HIMENO Kunisuke, 姫野 国祐
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tokushima University
  •  Development of Gene Therapy for Type I Diabetes Using Cytokine Gene and Pancreatic Islet B Cell-Specific Lymphocytes

    • Principal Investigator
      ITAKURA Mitsuo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokishima
  •  Mechanisms of opportunistic infection with protozoa in CD4^+T cell deficient ratsPrincipal Investigator

    • Principal Investigator
      HIMENO Kunisuke
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokushima
  •  移植臓器拒絶反応の免疫学的制御

    • Principal Investigator
      柏木 登
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General surgery
    • Research Institution
      Kitasato University
  •  抗腫瘍免疫を担うTリンパ球のT細胞レセプター遺伝子の解析

    • Principal Investigator
      吉開 泰信
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  Analysis of molecular mechanisms of T cell differentiation

    • Principal Investigator
      YOSHIKAI Yasunobu
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University

All 2008 2007

All Journal Article

  • [Journal Article] Antigen-specific CD8+T cells induced by the ubiquitin fusion degradation pathway.2008

    • Author(s)
      Imai T, Duan X, Hisaeda H, Himeno K.
    • Journal Title

      Biochem Biophys Res Commun 365

      Pages: 758-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Antigen-specific CD8^+ T cells induced by the ubiquitin fusion degradation pathway2008

    • Author(s)
      Imai T, Duan X, Hisaeda H, Himeno K
    • Journal Title

      Biochem Biophys Res Commun 365(4)

      Pages: 758-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Concurrent infection with Heligmosomoides polygyrus modulates murine host response against Plasmodium berghei ANKA infection.2008

    • Author(s)
      Tetsutani K, Ishiwata K, Torii M, Hamano S, Hisaeda H, Himeno K.
    • Journal Title

      Am J Trop Med Hyg 79

      Pages: 819-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells2008

    • Author(s)
      Hisaeda H, Tetsutani K, Imai T, Moriya C, Tu L, Hamano S, Duan X, Chou B, Ishida H, Aramaki A, Shen J, Ishii KJ, Coban C, Akira S, Takeda K, Yasutomo K, Torii M, Himeno K
    • Journal Title

      J Immunol 180(4)

      Pages: 2496-503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Ubiquitin-fusion degradation pathway : a new strategy for inducing CD8 cells specific for mycobacterial HSP65.2008

    • Author(s)
      Shen J, Hisaeda H, Chou B, Yu Q, Tu L, Himeno K.
    • Journal Title

      Biochera Biophys Res Commun 10

      Pages: 241-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells.2008

    • Author(s)
      Hisaeda H, Tetsutani K, Imai T, Moriya C, Tu L, Hamano S, Duan X, Chou B, Ishida H, Aramaki A, Shen J, Ishii KJ, Coban C, Akira S, Takeda K, Yasutomo K, Torii M, Himeno K.
    • Journal Title

      J Immunol 180

      Pages: 2496-503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Critical contribution of immunoproteasomes in the induction of protective immunity against Trypanosoma cruzi in mice vaccinated with a plasmid encoding a CTL epitope fused to green fluorescence protein2008

    • Author(s)
      Chou B, Hisaeda H, Shen J, Duan X, Imai T, Tu L, Murata S, Tanaka K, Himeno K
    • Journal Title

      Microbes Infect 10(3)

      Pages: 241-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Concurrent infection with Heligmosomoides polygyrus modulates murine host response against Plasmodium berghei ANKA infection2008

    • Author(s)
      Tetsutani K, Ishiwata K, Torii M, Hamano S, Hisaeda H, Himeno K
    • Journal Title

      Am J Trop Med Hyg 79(6)

      Pages: 819-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Ubiquitin-fusion degradation pathway : a new strategy for inducing CD8 cells specific for mycobacterial HSP652008

    • Author(s)
      Shen J, Hisaeda H, Chou B, Yu Q, Tu L, Himeno K
    • Journal Title

      Biochem Biophys Res Commun 365(4)

      Pages: 621-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Critical contribution of immunoproteasomes in the in duction of protective immunity against Trruzi in mice vaccinated with a plasmid encoding a CTL epitope fused to green fluorescence protein.2008

    • Author(s)
      Chou B, Hisaeda H, Shen J, Duan X, Imai T, Tu L, Murata S, Tanaka K, Himeno K.
    • Journal Title

      Microbes Infect 10

      Pages: 241-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Identification of Trypanosoma cruzi sublineages by the simple method of single-stranded conformation DNA polymorphism (SSCP)2007

    • Author(s)
      Higo H, Miura S, Agatsuma T, Mimori T, Yanagi T, Iwagami M, de Arias AR, Matta V, Hirayama K, Takeuchi T, Tada I, HimenoK
    • Journal Title

      Parasitol Res 100(5)

      Pages: 1023-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Immune therapy against tumors based on the ubiquitin-proteasome pathway2007

    • Author(s)
      Himeno K, Hisaeda H
    • Journal Title

      Fukuoka Igaku Zasshi(Review. Japanese) 98(8)

      Pages: 312-9

    • NAID

      120000987727

    • Data Source
      KAKENHI-PROJECT-19590429
  • [Journal Article] Malaria parasite induces tryptophan-related immune suppression inmice2007

    • Author(s)
      Tetsutani K, To H, Torii M, Hisaeda H, Himeno K
    • Journal Title

      Parasitology 134(Pt7)

      Pages: 923-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590429
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