SAJI Makoto 佐治眞理

… Alternative Names

SAIJI Makoto 佐治真理

佐治眞理サジマコト

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Researcher Number	50114179
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010 – 2011: 北里大学, 医療衛生学部, 教授 2001 – 2004: 北里大学, 医療衛生学部, 教授 2001 – 2002: 北里大学, 医療衛生学部, 教助 1999: 北里大学, 医療衛生部, 教授 1998: Kitasato Univ.Sch.of Allied Health Sciences, Dept.of Physiology, Professor, 医療衛生学部, 教授 1995 – 1997: 鳥取大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Neurology / Cerebral neurosurgery Except Principal Investigator Pediatrics / Psychiatric science / Neurology / General physiology
Keywords	Principal Investigator 神経細胞障害 / シナプシンI / アンチセンスDNA / abnormal synaptic plasticity / motor dysfunction / nigral knockdown / dopamine depletion / HVJ-liposome vector / early Parkinson's disease / synaptotagmin I … More / antisense / 運動疾患 / シンタキシン / ドーパミン放出 / 遺伝子発現抑制 / 回転運動異常 / パーキンソン病 / シナプトタグミン / シナプトタグミン I / 運動障害 / 黒質 / ノックダウン / ドーパミン枯渇 / HVJ-リポソームベクター / 早期パーキンソン病 / シナプトタグミンI / アンチセンス / kainic acid / hypothalamo-hippocampal afferent / synapsin I / antisense DNA / neuron death / hippocampal pyramidal cell / temporallobe epilepsy / 海馬内情報伝搬 / ゲーティング機構 / 上乳頭核-海馬系 / カイニン酸 / 視床下部-海馬入力 / 神経細胞死 / 海馬錐体細胞 / 側頭葉てんかん発作 / Hippocampus / Neuronal damage / Synapsin I / Brain ischemia / Synaptic transmission / Antisense DNA / 軸索輸送 / 海馬神経細胞死 / 海馬 / 脳虚血 / シナプス伝達 / NMDA-RサブユニットNR2Bアンタゴニスト / NMDA-R依存LTP誘導強化 / 運動症状改善後効果 / バーキンソン病モデル / 運動症状改善効果 / 視床下核(STN) / 深部脳刺激(DBS) / 片側パーキンソン病モデ / 基底核回路 / NMDA受容体NR2Bアンタゴニスト / 運動症状改善 / 視床下核 / 深部脳刺激 / 片側パーキンソン病モデル … More Except Principal Investigator dehydrodolichol reductase / asiolotransferrin / disialotransferrion / carbohydrate-deficient glycoprotein syndrome / シーター波 / 海馬 / PPI / behavior / nitric oxide / learning / knock down / NMDA receptor / プレパルスインヒビション / 行動 / 一酸化窒素 / 学習 / ノックダウンラット / NMDA受容体 / Carbohydrate-deficient / 遺伝病 / ドリコール / 小胞体 / 糖鎖 / 糖蛋白 / pre-pulse inhibition test / 中脳腹側被蓋野 / 認知機能 / 視床下核脳深部刺激療法 / パーキンソン病 / シータ波 / テレメーター / 自由行動 / 脳波 / 視床下部上乳頭核 / ゲーティング機構 / 記憶 / 歯状回 / CA2 / 上乳頭体核 / ライソゾーム病 / 神経遺伝病 / 神経細胞移植 / 神経前駆細胞 / 遺伝子治療 Less

パーキンソン病モデル動物での視床下核刺激による認知機能変化の検討
- Principal Investigator
  
  TAKIYAMA Youko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
Reorganization of basal ganglia circuitry in animal model of parkinson's disease by stimulation of subthalamic nucleusPrincipal Investigator
- Principal Investigator
  
  SAJI Makoto
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kitasato University
記憶情報処理における海馬ゲーティング機構の役割解明
- Principal Investigator
  
  AKITA Hisanao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Kitasato University
Study on Parkinson's disease model rats with antisense-induced nigral knockdown of synaptotagmin IPrincipal Investigator
- Principal Investigator
  
  SAJI Makoto
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
Hippocampal knock down of NMDA receptor induces deficit of PPI
- Principal Investigator
  
  SUZUKI Eiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kitasato University
視床下部神経活動による海馬内ニューロネットワークの制御機構
- Principal Investigator
  
  関野祐子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
Mechanism for hippocampal neuron damage following intra-amygdaloid kainic acid-induced limbic seizuresPrincipal Investigator
- Principal Investigator
  
  SAJI Makoto
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kitasato University
  Tottori University
Development of therapeutics for ischemic brain damge by interrupting synaptic transmissions with the intraventricular infusion of antisense DNAPrincipal Investigator
- Principal Investigator
  
  SAJI Makoto
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tottori University
Research on the basic defect of carbohydrate-deficient glycoprotein syndrome
- Principal Investigator
  
  OHNO Kousaku
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tottori University
遺伝子治療の基礎的研究:小児神経疾患のモデル動物を用いた神経細胞移植
- Principal Investigator
  
  OHNO Kousaku
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tottori University

All 2012 2011 2010

All Journal Article Presentation

[Journal Article] Evaluation of neurotoxicity of artificial dura mater and dura mater containing a high concentration of dibutyltin in rats after intracranial implantation2012
- Author(s)
  Tsunoda M, Ikeuchi R, Tsuji M, Inoue Y, Ito K, Katagiri H, Akita H, Saji M., Yuba T, Yamada T, Tsuchiya T, Aizawa Y
- Journal Title
  
  Kitasato Med J
  
  Volume: 42 Pages: 67-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659264
[Journal Article] Enhanced inhibitory effects of TBT chloride on the development of F_1 rats2010
- Author(s)
  Asakawa H, Tsunoda M, Kaido T, Hosokawa M, Sugaya C, Inouue Y, Kudo Y, Satoh T, Katagiri H, Akita H, Saji M, Wakasa M, Negish T, Tashiro T, Aizawa Y
- Journal Title
  
  Arch Environ ContamTaxicol
  
  Volume: 58 Pages: 1065-1073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659264
[Journal Article] Activation of the NMDA receptor involved in the alleviating after-effect of repeated stimulation of the subthalamic nucleus on motor deficits in hemiparkinsonia rats2010
- Author(s)
  Akita H, Honda Y, Ogata M, Noda K, Saji M
- Journal Title
  
  Brain Res
  
  Volume: 1306 Pages: 159-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] Switching from learning behavior to thigmotaxis in mater maze induced by in vivo delivery of antibody against AMPA receptor GluA1-C terminus via HVJ-E vector into hippocampal neurons in rats2011
- Author(s)
  Saji M, Shimizu D, Ogata M, Noda K, Suzuki N, Akita H
- Organizer
  41st annual meeting of society for neuroscience
- Place of Presentation
  Washington DC
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] Loss of motivation for learning in water maze by in vivo delivery of antibody to AMPA receptor GluR1-C terminus via HVJ-E vector into hippocampal CA1 neurons in rats2011
- Author(s)
  Saji M, Ogata M, Noda K, Suzuki N, Akita H
- Organizer
  IBRO world congress of neuroscience
- Place of Presentation
  Firenze, Italy
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] The neurotoxic effects of tributylin on mele F1 rats by continuous exposurefrom the fetal stage through their developing stages2011
- Author(s)
  Ikeuchi R, Kido T, Sugaya C, Tsunoda M, Katagiri H, Uchimura A, Akita H, Saji M, Aizawa Y
- Organizer
  50th annual meeting for societyof toxicology
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] NMDA receotpr-mediated plasticity in the alleviating after-effect of subthalamic stimulation on akinetic motor deficit in rat models of Parkinson's disease2010
- Author(s)
  Akita H, Honda Y, Ogata, Noda K, Saji M
- Organizer
  40th annual meeting of society for neuroscience
- Place of Presentation
  San Diego
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] NMDAR-mediated synaptic plasticity involved in the alleviating after-effect of STN-DBS on akinetic motor deficits in Parkinson's model rats.2010
- Author(s)
  Akita H, Honda Y, Ogata M, Ogura T, Saji M
- Organizer
  Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] Paclitaxel-induced hyperalgesia modulates NR1 receptor expression in the frontal cortex and negative affective component of pain in rats2010
- Author(s)
  Noda K, Akita H, Ogata M, Saji M
- Organizer
  13th world congress on pain
- Place of Presentation
  Montreal
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-22659264
[Presentation] Evaluation of TBT neurotoxicity in developing male F1 rats by open field tests2010
- Author(s)
  Tsunoda M, Kado T, Ikeuchi R, Hosokawa M, Sugaya C, Inoue Y, Kudo Y, Akita H, Saji M, Takeuchi Y, Yoshioka R, Tashiro T, Aizawa Y
- Organizer
  49th Annual Meeting for Society of Toxicology
- Place of Presentation
  Salt Lake City
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-22659264

1. OHNO Kousaku (70112109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. AKITA Hisanao (70118777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NODA Kazuko (60050704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAKIYAMA Youko (60265593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SATO Sumito (40266052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HIGAKI Katsumi (90294321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUZUKI Nobuyuki (10050650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZUKI Eiji (60226496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NIBUYA Masashi (00228256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIYAOKA Hitoshi (40209862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石田玄 (30252860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 関野祐子 (70138866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 白尾智明 (20171043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 緒形雅則 (20194425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐藤正弘 (10273898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAJI Makoto 佐治 眞理

SAIJI Makoto 佐治 真理

佐治 眞理 サジ マコト

Research Projects

Research Products

Co-Researchers

パーキンソン病モデル動物での視床下核刺激による認知機能変化の検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reorganization of basal ganglia circuitry in animal model of parkinson's disease by stimulation of subthalamic nucleusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

記憶情報処理における海馬ゲーティング機構の役割解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on Parkinson's disease model rats with antisense-induced nigral knockdown of synaptotagmin IPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hippocampal knock down of NMDA receptor induces deficit of PPI

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

視床下部神経活動による海馬内ニューロネットワークの制御機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Mechanism for hippocampal neuron damage following intra-amygdaloid kainic acid-induced limbic seizuresPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of therapeutics for ischemic brain damge by interrupting synaptic transmissions with the intraventricular infusion of antisense DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the basic defect of carbohydrate-deficient glycoprotein syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝子治療の基礎的研究:小児神経疾患のモデル動物を用いた神経細胞移植

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Evaluation of neurotoxicity of artificial dura mater and dura mater containing a high concentration of dibutyltin in rats after intracranial implantation2012

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced inhibitory effects of TBT chloride on the development of F_1 rats2010

Author(s)

Journal Title

Data Source

[Journal Article] Activation of the NMDA receptor involved in the alleviating after-effect of repeated stimulation of the subthalamic nucleus on motor deficits in hemiparkinsonia rats2010

Author(s)

Journal Title

Data Source

[Presentation] Switching from learning behavior to thigmotaxis in mater maze induced by in vivo delivery of antibody against AMPA receptor GluA1-C terminus via HVJ-E vector into hippocampal neurons in rats2011

Author(s)

Organizer

SAJI Makoto 佐治眞理

SAIJI Makoto 佐治真理

佐治眞理サジマコト