SHINOYAMA Yuhei 下山雄平

Researcher Number	50123948
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Affiliation *help	2006 – 2008 : 室蘭工業大学, 工学部, 教授 1996 – 2003 : 北海道教育大学, 教育学部, 教授 1995 – 2001 : 北海道教育大学, 教育学部・函館校, 教授 1997 : 北海道教育大学教育学部, 函館枝, 教授 1995 – 1996 : Hokkaido University of Education, Faculty of Education Professor, 教育学部函館校, 教授 … More
Review Section/Research Field	Principal Investigator Applied materials science/Crystal engineering / Applied materials / Applied physics, general Except Principal Investigator Measurement engineering / Applied veterinary science / 高分子物性 / Applied materials / Electronic materials/Electric materials / Applied materials science/Crystal engineering / Biological Sciences
Keywords	Principal Investigator Vector ESR / Pulse-ESR / 生体オキシメトリー / 空間次元 / ホワイトノイズ磁場変調 / ホワイト・ノイズ変調 / 飽和移動電子スピン共鳴 / 位相信号 / continuous wave / ベクトル信号 … More Except Principal Investigator EPR / ESR / 電子常磁性共鳴 / 部位特異的スピンラベル法 / AMC / ATC / 構造生物学 / プリオン / CJD / FM / インビボ / スピンラベル法 / 磁界 / 電子スピン共鳴 / 電子スピン共鳴(ESR) / 共振器 / ループ・ギャップ共振器 / ELECTRON SPIN RESONANCE (ESR) / homogeneity / RELAXATION TIME CONSTANT / Solid-State Polymerization / 振動 / in-situ Observation / Vibration / エレクトロン / waveguide with flange / 切り離し導波管 / スペクトロメータ / Amplitude Spectrum / PEDRI / 異常型プリオン / magnetic field / 癌 / LB Method / マイクロ波アプリケータ / 磁界変調 / 脳機能 / 高周波パルス増幅器 / フランジ付導波管 / 蛍光顕微鏡 / IN VIVO MEARSUREMENT / サーフェイスコイル共振器 / 二重共鳴 / Differential Interference Microscope / ELECTRON SPIN ECHO (ESE) / ELECTRON PARAMAGNETIC RESONANCE (EPR) / プロトン・エレクトロン二重共鳴 / 電子スピン共鳴法 / 銅イオン / 連続波 / 動的構造変化 / TE_<101> cavity resonator / 強度スペクトル / Electron Spin Echo (ESE) / AFM / AFC / dog head / 周波数変調 / 好中球 / 磁気共鳴 / Phase Spectrum / Moleculau Orientation / プロトン / 自動チューニング回路 / PULSE / 単分子膜 / プリオンタンパク質 / Polyacetylene / マルチ変調 / Vector ESR / 生体計測 / Large Domain / ポリジアセチレン / cerebral function / Polydiacetylene Monolayer / 有機単分子膜 / モノドメイン / パルスESR / NADPHオキシダーゼ / パルス / 蛋白リン酸化酵素 / 突然変異 / BSE / resonator / 格子終端TE_<101>空胴共振器 / 位相スペクトル / リン酸化 / 犬頭部 / microwave applicator / マルチ変調法 / Saturation Transfer / CW / Spin-lattice relaxation / ラジオ波 / NMR / Fluorescence Microscope / イメージング / cut waveguide / 距離情報 / 蛍光偏光 / 水面上単分子膜 / 光重合 / ESE(電子スピンエコー) / 距離計測 / 双極子相互作用 / 直接観察 / 共振周波数 / EPRI / スピン-スピン緩和 / マレイミド / ポリアセチレン / 細隙開口導波管 / Multiple Modulation / conducting plate / Double resonance / 飽和移動 / マイクロ波 / 電子スビン共鳴(ESR) / 老化 / ベクトルESR分光法 / パルスシーケンス / 主体計測 / スピン-格子緩和 / LB膜 / 人畜共通感染症 / 結晶成長 / 緩和時定数 / 同時共鳴 / ベクトルESR / 電子スピンエコー / MRI Less

Molecular imaging of prion protein by atomic force microscop yand a novel electro-spin-resonance techniques
- Principal Investigator
  
  I NANAML Osamu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
プリオンと銅イオン相互作用の新しいパルス電子スピン共鳴法を用いたアプローチ
- Principal Investigator
  
  稲波修
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
Development of an EPR imager for the cerebral function analysis
- Principal Investigator
  
  ONO Mitsuhiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Measurement engineering
- Research Institution
  Yamagata University
NADPHオキシダーゼコンポーネントp47^<phox>のSH3Aドメインの構造解析 ―部位特異的スピンラベル法と飽和移動法による研究―
- Principal Investigator
  
  I NANAML Osamu
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
ヒューマン・ホールボディ電子常磁性共鳴イメージング
- Principal Investigator
  
  ONO Mitsuhiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Measurement engineering
- Research Institution
  Yamagata University
Development of a FM-EPR instrument
- Principal Investigator
  
  ONO Mitsuhiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Measurement engineering
- Research Institution
  Yamagata University
液体電子スピン量子計算機-電子常磁性共鳴によるアプローチPrincipal Investigator
- Principal Investigator
  
  下山雄平
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied physics, general
- Research Institution
  Hokkaido University of Education
Study of PEDRI (Proton Electron Double Resonance Imaging)
- Principal Investigator
  
  ONO Mitsuhiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Measurement engineering
- Research Institution
  Yamagata University
DEVELOPMENT OF 350MHz PULSED EPR SPECTROMETER
- Principal Investigator
  
  ONO Mitsuhiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied materials science/Crystal engineering
- Research Institution
  YAMAGATA UNIVERSITY
Growth Mechanism of Polydiacetylene Monolayer at the Air-Water Interface
- Principal Investigator
  
  YAMADA Susumu
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Electronic materials/Electric materials
- Research Institution
  TOMAKOMAI NATIONAL COLLEGE OF TECHNOLOGY
Development of Multi-frequency Vector EPR Spectrometer by White-noise Field Modulation Method.Principal Investigator
- Principal Investigator
  
  SHIMOYAMA Yuhei
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied materials science/Crystal engineering
- Research Institution
  Hokkaido University of Education
Dynamic Structure of Biosupramole cular System.Principal Investigator
- Principal Investigator
  
  SHIMOYAMA Yuhei, 亘弘
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  HOKKAIDO UNIVERSITY OF EDUCATION
  Okazaki National Research Institutes
Development of Vector ESR Spectrometer with Multiple Modulation ProtocolPrincipal Investigator
- Principal Investigator
  
  MATSUKI Kiyoshi, 下山雄平
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Applied materials
- Research Institution
  Hokkaido University of Education, Hakodate
ベクトル概念による飽和移動電子スピン共鳴法の開発Principal Investigator
- Principal Investigator
  
  下山雄平
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Applied materials
- Research Institution
  Hokkaido University of Education
Electron Spin Echo (ESE) Studies on Electronic State of Polyacetylene
- Principal Investigator
  
  JUNKICHI Sohma
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  高分子物性
- Research Institution
  Hokkaido University

All 2008 2007 2006

All Journal Article Presentation

[Journal Article] Instability of familial spongiform encephalopathy-related prion mutants2008
- Author(s)
  Watanabe Y, Hiraoka.W, Shimoyama Y,Horiuchi M, Kuwabara M. and Inanami O.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 366
  
  Pages : 244-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380172
[Journal Article] 2008. Dynamics and local ordering of spin-labeled prion protein : an ESR simulationstudy of a highly PH-sensitive site2008
- Author(s)
  Chiang Y.W, Otoshima Y, Watanabe Y, Inanami O, Shimoyama Y
- Journal Title
  
  J. Biomol. Struct Dyn 26
  
  Pages : 355-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380172
[Journal Article] Instability of familial spongiform encephalopathy-related prionmutants2008
- Author(s)
  Watanabe, Y., Hiraoica, W., Shimoyama, Y., Horiuchi, M., Kuwabara. M. and Inanami. O.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 366
  
  Pages : 244-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380172
[Journal Article] Identification of pH-sensitive regions in the mouse prion by the cysteine-scanning spin-labeling ESR technique.2006
- Author(s)
  Watanabe Y, nanami O, Horiuchi M, Hiraoka W, Shimoyama d, Fuyuhiko Y, Inagaki F, Kuwabara M
- Journal Title
  
  Biochemical and Biophysical Research Communications. 350(3)
  
  Pages : 549-556
- Data Source
  KAKENHI-PROJECT-18658118
[Presentation] Characterization of Cu (II) binding site in C-terminal domain of mouse prion : Site-directed spin labeling study2008
- Author(s)
  Osamu INANAMI, Yasuko WATANABE, Wakako HIROOKA, Yuhei SHIMOYAMA, Motohiro HORIUCHI and Mikinori KUWABARA
- Organizer
  EPR2008 (Biomedical Redox Navigation)
- Place of Presentation
  JAL Resort Sea Hawk Hotel Fukuoka, Kyushu Japan
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] Characterization of Cu(II)binding site in C-terminal domain of mouse prion : Site-directed spin labeling study EPR2008 (Biomedical Redox Navigation2008
- Author(s)
  Osamu INANAMI,Yasuko WATANABE,Wakako HIROOKA,Yuhei SHIMOYAMA,Motohiro HORIUCHI and Mikinori KUWABARA
- Organizer
  JAL Resort Sea Hawk Hotel Fukuoka
- Place of Presentation
  Kyushu Japan
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] Analysis of pH-sensitivity and conformational stability in mouse prion protein by cysteine-scanning site-directed spin labeling2007
- Author(s)
  Watanabe Y, Hiraoka W, Shimoyama Y, Horiuchi M, Kuwabara M, and Inanami O.
- Organizer
  Society of Electron Spin Scoence and Technology(ISESS-SEST)2007
- Place of Presentation
  Granship(Shizuoka, Japan)
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-18658118
[Presentation] プリオンタンパク質C末端領域の新たなCu^<2+>結合構造の同定2007
- Author(s)
  稲波修、渡辺康子、堀内基広、平岡和佳子、下山雄平、桑原幹典、
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  酪農学園大学(江別市)
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-18658118
[Presentation] Analysis of pH-sensitivity and conformational stability in mouse prion protein by cysteine-scanning site-directed spin labeling2007
- Author(s)
  Watanabe Y, Hiraoka W, Shimoyama Y, Ho riuchi M, Kuwabara M and Inanami O.
- Organizer
  Society of Electron Spin Scoence and Technology (ISESS -SEST)
- Place of Presentation
  Granship (Shizuoka, Japan)
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] プリオンタンパク質C末端領域の新たなCu^2+結合構造の同定2007
- Author(s)
  稲波修、渡辺康子、堀内基広、平岡和佳子、下山雄平、桑原幹典、
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  酪農学園大学(江別市)
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] Identication of Cu(II) b inding site incarb ox y-terminal domain of mouse PrPsc Site-directed spin lab study2007
- Author(s)
  Inanami O, Watanabe Y, Hiraoka W, Shimoyama Y, Horiuchi M, Inagaki F and Kuwabara M.
- Organizer
  Society of Electron Spin Scoence and Technology (ISESS SEST)
- Place of Presentation
  Granship (Shizuoka, Japan)
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] Identication of Cu(II)b inding site incarb ox y-terminal domain of mouse PrP^sc Site-directed spin lab study2007
- Author(s)
  Inanami O, Watanabe Y, Hiraoka W, Shimoyama Y, Horiuchi M, Inagaki F and Kuwabara M.
- Organizer
  Society of Electron Spin Scoence and Technology(ISESS-SEST)2007
- Place of Presentation
  Granship(Shizuoka, Japan)
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] プリオンタンパク質のpH感受性における塩橋とヒスチジン残基の役割2007
- Author(s)
  渡辺康子、平岡和佳子、下山雄平、堀内基広、桑原幹典、稲波修
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  酪農学園大学(江別市)
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] プリオンタンパク質のpH感受性における塩橋とヒスチジン残基の役割2007
- Author(s)
  渡辺康子、平岡和佳子、下山雄平、堀内基広、桑原幹典、稲波修
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  酪農学園大学(江別市)
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] プリオンタンパク質C末端領域の新たなCu2+結合構造の同定2007
- Author(s)
  稲波修、渡辺康子、堀内基広、平岡和佳子、下山雄平、桑原幹典
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  酪農学園大学(江別市)
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19380172
[Presentation] プリオンタンパク質のpH感受性における塩橋とヒスチジン残基の役割2007
- Author(s)
  渡辺康子、平岡和佳子、下山雄平、堀内基広、桑原幹典、稲波修
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  酪農学園大学(江別市)
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-18658118
[Presentation] Identication of Cu(II)b inding site incarb ox y-terminal domain of mouse PrP^Sc Site-directed spin lab study2007
- Author(s)
  Inanami O, Watanabe Y, Hiraok a W, Shimoyama Y, Horiuchi M, Inagaki F and Kuwabara M.
- Organizer
  Society of Electron Spin Scoence and Technology(ISESS-SEST)2007
- Place of Presentation
  Granship(Shizuoka, Japan)
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-18658118
[Presentation] Analysis of pH-sensitivity and conformational stability in mouse prion protein by cysteine-scanning site-directed spin labeling2007
- Author(s)
  Watanabe Y, Hiraoka W, Shimoyama Y, Horiuchi M, Kuwabara M, and Inanami O.
- Organizer
  Society of Electron Spin Scoence and Technology(ISESS-SEST)2007
- Place of Presentation
  Granship(Shizuoka, Japan)
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19380172

1. ONO Mitsuhiro (60007010)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
2. HIRATA Hiroshi (60250958)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
3. I NANAML Osamu (10193559)

# of Collaborated Projects : 3results

# of Collaborated Products : 17results
4. YAMAMOTO Tetsuya (30312755)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. WATARI Hiroshi (10079692)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. MATSUKI Kiyoshi (00157281)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
7. SUZUKI Hirosuke

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
8. KUWABARA Mikinori (10002081)

# of Collaborated Projects : 2results

# of Collaborated Products : 12results
9. HIRAOKA Wakako (00212168)

# of Collaborated Projects : 2results

# of Collaborated Products : 11results
10. AKATSUKA Takao (80091875)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
11. YOSHIDA Ekuo

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
12. FUJII Kanae

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
13. INABA Mutsumi (00183179)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. HORIUTCHI Motohiro (30219216)

# of Collaborated Projects : 1results

# of Collaborated Products : 11results
15. ASANUMA Katetoshi (40332473)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. FUJII Hirotada (70209013)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. ERA Seiichi (30152002)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. OOYA Hiroaki (00025389)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. MAKINO Keisuke (50159141)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. NISHIKAWA Hiroyasu (40079695)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. YAMADA Susumu (80182533)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. JUNKICHI Sohma (00001115)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. SHIOTANI Masaru (80002137)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. TABATA Masayoshi (50091476)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. OHNO Keiichi (00001298)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. YOSHIDA Hiroshi (20027410)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. 太田利男 (20176895)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. 湯浅哲也 (30240146)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
29. HANIWA Masatoshi

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
30. HYDE Jim

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
31. BUDIL Dave B

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
32. SWARTZ Harol

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
33. EHRNBERG And

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
34. BERLINER Lau

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
35. FREED Jack

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
36. HAROLD Swartz

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
37. LAURENCE Berliner

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
38. ANDES Ehrenberg

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
39. JACK Freed

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
40. DAVE Budil

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
41. JIM Hyde

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
42. HYDE J.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
43. BUDIL D.B.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
44. SWARTZ H.M.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
45. KOSCIELNIAK

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
46. EHRNBERG A.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
47. BERLINER L.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
48. FREED J.H.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

SHINOYAMA Yuhei 下山 雄平

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液体電子スピン量子計算機-電子常磁性共鳴によるアプローチPrincipal Investigator

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Development of Multi-frequency Vector EPR Spectrometer by White-noise Field Modulation Method.Principal Investigator

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Dynamic Structure of Biosupramole cular System.Principal Investigator

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Development of Vector ESR Spectrometer with Multiple Modulation ProtocolPrincipal Investigator

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ベクトル概念による飽和移動電子スピン共鳴法の開発Principal Investigator

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SHINOYAMA Yuhei 下山雄平