NAKAYAMA Hitoshi 中山均

Researcher Number	50133195
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006 – 2008: 奈良県立医科大学, 医学部, 講師 1999 – 2000: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology Except Principal Investigator General pharmacology
Keywords	Principal Investigator CREB / MAP kinase / NGF / cAMP / nicotinic / nicotine / protein phosphorylation / acetylcholine receptor / PC12細胞 / ニコチン性 / ニコチン / 蛋白リン酸化 / アセチルコリン受容体 … More Except Principal Investigator … More TNF-α / Big MAP kinase 1 / MAPキナーゼ / インスリン抵抗性 / メタボリックシンドローム / blood flow / vascular injury / Diabetes Mellitus / insulin resistance / Metabolic Syndrome / MAP kinases / 炎症 / アンジオテンシンII / 血流 / 血管障害 / 糖尿病 / 抗酸化療法 / 薬理学 / BMK1 / シグナル伝達 / 酸化ストレス Less

Investigation of the involvement of oxidative stress in metabolic syndrome and the development of new anti-oxidants
- Principal Investigator
  
  YOSHIZUMI Masanori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nara Medical University
Physiological significance of big mitogen-activated protein kinase 1 in metabolic syndrome
- Principal Investigator
  
  YOSHIZUMI Masanori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nara Medical University
Studies on signal transduction mechanisms from nicotinic acetylcholine receptors to nucleusPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Hitoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nara Medical University

All 2011 2010 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 平成21年度住居医学共同研究成果報告集2010
- Author(s)
  中山均、吉栖正典
- Total Pages
  287
- Publisher
  奈良県立医科大学住居医学大和ハウス寄附講座
- Data Source
  KAKENHI-PROJECT-20590258
[Journal Article] Big Mitogen-activated Protein Kinase 1 Protects Cultured Rat Aortic Smooth Muscle Cells from Oxidative Damage.2011
- Author(s)
  Jing Zhao, Yoji Kyotani, Satoyasu Itoh, Hitoshi Nakayama, Minoru Isosaki, Masanori Yoshizumi
- Journal Title
  
  J.Pharmacol.Sci. 115 印刷中
- NAID
  10029894630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590258
[Journal Article] Olmesartan inhibits angiotensin II-induced migration of vascular smooth muscle cells through Src and MAP kinase pathways.2010
- Author(s)
  Yoji Kyotani, Jing Zhao, Sayuko Tomita, Hitoshi Nakayama, Minoru Isosaki, Masayuki Uno, Masanori Yoshizumi
- Journal Title
  
  J.Pharmacol.Sci. 113(2)
  
  Pages: 161-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590258
[Journal Article] Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells2009
- Author(s)
  Nakayama H, ほか
- Journal Title
  
  Clin.Exp.Pharmacol.Physiol. 36
  
  Pages: 1183-1185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590258
[Journal Article] Neuroprotective effects of pramipexole against tunicamycin-induced celldeath in PC12 cells.2009
- Author(s)
  Nakayama H, Zhao J, Amany El-Fakharany, Isosaki M, Satoh H, Kyotani Y, Yoshizumi M.
- Journal Title
  
  Clin.Exp.Pharmacol.Physiol. 36
  
  Pages: 1183-1185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590258
[Journal Article] ER stress is the initial response to polyglutamine toxicity in PC12 cells2008
- Author(s)
  Nakayama H, ほか
- Journal Title
  
  Biochem. Biophys. Res. Commun. 377(2)
  
  Pages: 550-555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590258
[Journal Article] ER stress is the initial response to polyglutamine toxicity in PC12 cells.2008
- Author(s)
  Nakayama H, Hamada M, Fujikake N, Nagai Y, Zhao J, Hatano O, Shimoke K, Isosaki M, Yoshizumi M, Ikeuchi T.
- Journal Title
  
  Biophys.Res.Commun. 377(2)
  
  Pages: 550-555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] PC12細胞における細胞表面膜受容体のビオチン化2011
- Author(s)
  中山均、趙晶、吉栖正典
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜(誌上開催)
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] 酸化ストレスによる血管平滑筋細胞死におけるSrcとBMK1/ERK5の役割2011
- Author(s)
  趙晶、京谷陽司、富田小優子、中山均、磯崎稔、佐藤広康、吉栖正典
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜(誌上開催)
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] 酸化ストレスによる血管平滑筋細胞死におけるBMK1/ERK5の役割2010
- Author(s)
  趙晶、京谷陽司、富田小優子、中山均、佐藤広康、磯崎稔、吉栖正典
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] PC12細胞における細胞表面膜受容体の同定2010
- Author(s)
  中山均、吉栖正典
- Organizer
  第33回日本分子生物学会年回・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] 喫煙が細胞膜受容体に与える影響-外膜蛋白質の特異的定量法の検討2010
- Author(s)
  中山均、吉栖正典
- Organizer
  2010年度「住居医学」共同研究成果報告会
- Place of Presentation
  奈良県立医科大学
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] アンジオテンシンIIによるSrcおよびMAPキナーゼを介した血管平滑筋細胞の遊走に対するオルメサルタンの阻害作用2010
- Author(s)
  京谷陽司、趙晶、富田小優子、佐藤広康、中山均、磯崎稔、宇野雅之、吉栖正典
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] 酸化ストレスによる培養ラット大動脈平滑筋細胞死におけるSrc及びBMK1/ERK5の役割の検討2010
- Author(s)
  趙晶、京谷陽司、富田小優子、中山均、磯崎稔、佐藤広康、吉栖正典
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] ウォルトマンニン活性に対するSH還元剤の影響2009
- Author(s)
  磯崎稔、中山均、佐藤広康、吉栖正典
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] PC12細胞におけるポリグルタミン酸誘導小胞体ストレスおよび細胞内シグナリングに対するポリグルタミン鎖長の影響2009
- Author(s)
  中山均、エルファカラニイアマニイ、趙晶、磯崎稔、佐藤広康、吉栖正典
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] Angiotensin IIによる血管平滑筋細胞の遊走に対するOlmesartanの阻害効果2009
- Author(s)
  京谷陽司、趙晶、富田小優子、佐藤広康、中山均、磯崎稔、宇野雅之、吉栖正典
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] 酸化ストレスによる培養ラット大動脈平滑筋細胞死におけるBMK1/ERK5の役割の検討2009
- Author(s)
  趙晶、京谷陽司、富田小優子、中山均、磯崎稔、佐藤広康、吉栖正典
- Organizer
  第116回日本薬理学会近畿部会
- Place of Presentation
  大津
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] ボリグルタミン発現PC12細胞におけるプロテアソーム障害と小胞体ストレスの関係2008
- Author(s)
  中山均, ほか
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] ポリグルタミン発現PC12細胞におけるプロテアソーム障害と小胞体ストレスの関係2008
- Author(s)
  中山均, ほか
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] Relationship between the proteasome impairment And the ER stress in polyglutamine-expressed PC12 cells.2008
- Author(s)
  Hitoshi, Nakayama, et. al.
- Organizer
  81th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] PC12h細胞におけるツニカマイシンによる細胞死に対するプラミペキソールの影響2008
- Author(s)
  趙晶、中山均、京谷陽司、磯崎稔、佐藤広康、吉栖正典
- Organizer
  第114回日本薬理学会近畿部会
- Place of Presentation
  神戸
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-20590258
[Presentation] Effects of proteasome inhibitor on tunicamycin thapsigargin, and polyglutamine-induced ER stress in PC12 cells2007
- Author(s)
  Hitoshi, Nakayama, et. al.
- Organizer
  80th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Nagoya, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] PC12細胞におけるツニカマイシン、タプシガルギン、ポリグルタミン誘導小胞体ストレスに対するプロテアソーム阻害剤の影響2007
- Author(s)
  中山均, ほか
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] Effects of proteasome inhibitor on tunicamycin-, Thapsigargin-, and polyglutamine-induced ER stress and cell death in PC12 cells.2007
- Author(s)
  Hitoshi, Nakayama, et. al.
- Organizer
  50th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] PC12細胞におけるッニカマイシン、タプシガルギン、ポリグルタミン誘導ERストレスに対するプロテアソーム阻害剤の影響2007
- Author(s)
  中山均, ほか
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] Effect of pramipexole on oxidative stress and ER stress in PC12 cells2006
- Author(s)
  Hitoshi Nakayama, ほか
- Organizer
  10th International Congress of Parklnson Dlsease and Movement Disorders
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590238
[Presentation] Effect of pramipexole on oxidative stress and ER stress in PC12 cells2006
- Author(s)
  Hitoshi, Nakayama, et. al.
- Organizer
  10th International Congress of Parkinson Disease and Movement Disorders
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590238

1. YOSHIZUMI Masanori (60294667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. SATOH Hiroyasu (90150309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. ISOSAKI Minoru (60159811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. HATANAKA Hiroshi (14401859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ZHAO Jing

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
6. KYOTANI Yoji

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. NAKAGAWA Tokiwa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAYAMA Hitoshi 中山 均

Research Projects

Research Products

Co-Researchers

Investigation of the involvement of oxidative stress in metabolic syndrome and the development of new anti-oxidants

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological significance of big mitogen-activated protein kinase 1 in metabolic syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on signal transduction mechanisms from nicotinic acetylcholine receptors to nucleusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 平成21年度住居医学共同研究成果報告集2010

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Big Mitogen-activated Protein Kinase 1 Protects Cultured Rat Aortic Smooth Muscle Cells from Oxidative Damage.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Olmesartan inhibits angiotensin II-induced migration of vascular smooth muscle cells through Src and MAP kinase pathways.2010

Author(s)

Journal Title

Data Source

[Journal Article] Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells2009

Author(s)

Journal Title

Data Source

[Journal Article] Neuroprotective effects of pramipexole against tunicamycin-induced celldeath in PC12 cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] ER stress is the initial response to polyglutamine toxicity in PC12 cells2008

Author(s)

Journal Title

Data Source

[Journal Article] ER stress is the initial response to polyglutamine toxicity in PC12 cells.2008

Author(s)

Journal Title

Data Source

[Presentation] PC12細胞における細胞表面膜受容体のビオチン化2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 酸化ストレスによる血管平滑筋細胞死におけるSrcとBMK1/ERK5の役割2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 酸化ストレスによる血管平滑筋細胞死におけるBMK1/ERK5の役割2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PC12細胞における細胞表面膜受容体の同定2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 喫煙が細胞膜受容体に与える影響-外膜蛋白質の特異的定量法の検討2010

Author(s)

Organizer

Place of Presentation

Year and Date

NAKAYAMA Hitoshi 中山均