HIRAO Ichiro 平尾一郎

… Alternative Names

HIRANO Ichiro 平尾一郎

平尾一郎ヒラオイチロウ

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Researcher Number	50173216
External Links
Affiliation (based on the past Project Information) *help	2015: 国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, チームリーダー 2014: 独立行政法人理化学研究所, ライフサイエンス技術基盤研究センター, チームリーダー 2008 – 2010: 独立行政法人理化学研究所, 核酸合成生物学研究チーム, チームリーダー 2007: 独立行政法人理化学研究所, 核酸合成生物学研究チーム、, チームリーダー 2004 – 2005: 東京大学, 先端科学技術研究センター, 科学技術振興特任教員(特任教授) … More 2003: 東京大学, 先端科学技術センター, 科学技術振興特任教員(常勤形態) 1992: 東京薬科大学, 薬学部, 助教授 1990 – 1991: 東京大学, 工学部, 助手 1986 – 1988: 東京大学, 工学部, 助手 Less
Review Section/Research Field	Principal Investigator Chemistry related to living body / Bio-related chemistry / Living organism molecular science Except Principal Investigator 分子遺伝学・分子生理学
Keywords	Principal Investigator 人工塩基対 / アプタマー / ファ-ジG4の複製開始機構 / translation / transcription / replication / artificial proteins / artificial nucleic acids / unnatural base pairs / 飜訳 … More / 翻訳 / 転写 / 複製 / 人工タンパク質 / 人工核酸 / ゼノバイオロジー / 合成生物学 / 遺伝情報拡張技術 / 進化工学 / 核酸 / バイオテクノロジー / 生体分子 / SELEX / in vitroセレクション / PCR / 核酸アプタマー / GCGAAAGC断片 / 複製開始機構 / ファージφX174 / ファージG4 / ミニヘアピン構造 / DNAの安定なヘアピン構造 / in vitroタンパク質合成系 / DNA・RNAの安定なヘアピン構造 / DNAのヘアピン構造 / DNAの異常構造 … More Except Principal Investigator 遺伝子の情報発現 / リボソーム / メッセンジャーRNA(mRNA) / 核酸の化学合成 / 転移RNA(tRNA) / RNA / タンパク質合成 / eukaryote / gene expression / ribosome / messenger RNA (mRNA) / protein synthesis / タンパク貭合成 / 遺伝情報発現の調節 / 真核細胞 / タンパク質合成リボ核酸 / リボ核酸 Less

人工塩基対による遺伝情報の拡張技術の細胞システムへの応用Principal Investigator
- Principal Investigator
  
  平尾一郎
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Institute of Physical and Chemical Research
Creation of highly-functional nucleic acids by unnatural base pair systemsPrincipal Investigator
- Principal Investigator
  
  HIRAO Ichiro
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research
Creation of extra base pairs for the development of novel functional nucleic acidsPrincipal Investigator
- Principal Investigator
  
  HIRANO Ichiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo
安定なヘアピン様構造を形成するRNA断片の合成と構造解析Principal Investigator
- Principal Investigator
  
  平尾一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
一本鎖DNAとして特殊構造を示すDNA配列とタンパク質の特異的相互作用Principal Investigator
- Principal Investigator
  
  平尾一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
一本鎖DNAとして特殊構造を示すDNA配列とタンパク質の特異的相互作用Principal Investigator
- Principal Investigator
  
  平尾一郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
異常に安定なDNAのミニヘアピン構造とタンパク質との特異的相互作用Principal Investigator
- Principal Investigator
  
  平尾一郎
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Pharmacy and Life Science
人工的タンパク質合成系の研究
- Principal Investigator
  
  MIURA Kin-ichiro
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
人工的タンパク質合成系の研究
- Principal Investigator
  
  三浦謹一郎
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
Relationship between efficiency of protein synthesis and structure of messenger RNA
- Principal Investigator
  
  MIURA Kin-ichiro
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo, Faculty of Engineering

All 2015 2014 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

[Book] Synthetic Biology (Synthetic Genetic Polymers Functioning to Store and Propagate Information by Genetic alphabet expansion.)2015
- Author(s)
  I. Hirao (ed. Robert A. Meyers)
- Total Pages
  742
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-26248043
[Book] The Chemical Biology of Nucleic Acids (Creation of Unnatural Base Pair Systems Toward New DNA/RNA Biotechnologies.)2014
- Author(s)
  I. Hirao and M. Kimoto (eds V.A. Erdmann, W.T. Markiewicz, J. Barciszewski)
- Total Pages
  599
- Publisher
  Splinger
- Data Source
  KAKENHI-PROJECT-26248043
[Book] 核酸化学のニュートレンド2011
- Author(s)
  平尾一郎
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-19201046
[Book] 核酸実験の原理とプロトコール2011
- Author(s)
  平尾一郎・胡桃坂仁志編著
- Total Pages
  264
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19201046
[Book] 医学のあゆみ2011
- Author(s)
  平尾一郎
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19201046
[Book] The Chemical Biology of Nucleic Acids, Expansion of the Genetic Alphabet in Nucleic Acids by Creating New Base Pairs2010
- Author(s)
  平尾一郎
- Publisher
  John Wiley & Sons(in press)
- Data Source
  KAKENHI-PROJECT-19201046
[Book] Methods in Molecular Biology, Site-Specific Incorporation of Extra Components into RNA by Transcription Using Unnatural Base Pair Systems2010
- Author(s)
  平尾一郎
- Publisher
  Humana Press(in press)
- Data Source
  KAKENHI-PROJECT-19201046
[Book] The Chemical Biology of Nucleic Acids2010
- Author(s)
  I. Hirao, M. Kimoto
- Data Source
  KAKENHI-PROJECT-19201046
[Book] Protein Engineering. (eds C. Kohrer, U. L. RajBhandary, Cell-free synthesis of proteins with unnatural amino acids. The PURE system and expansion of the genetic code.)2009
- Author(s)
  I. Hirao, T. Kanamori, T. Ueda
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19201046
[Book] Protein Engineering2009
- Author(s)
  I. Hirao, T. Kanamori, T. Ueda
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19201046
[Book] 遺伝子医学MOOK、最新RNAと疾患研究2009
- Author(s)
  平尾一郎
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-19201046
[Book] 遺伝子医学MOOK RNAと創薬2006
- Author(s)
  平尾一郎
- Total Pages
  228
- Publisher
  アプタマー創薬アプタマーによるシグナル伝達の阻害と制癌戦略
- Data Source
  KAKENHI-PROJECT-15350097
[Book] バイオニクス2006
- Author(s)
  村上裕, 菅裕明, 平尾一郎
- Total Pages
  92
- Publisher
  セントラルドグマを作り変える.
- Data Source
  KAKENHI-PROJECT-15350097
[Book] RNAと創薬2006
- Author(s)
  平尾一郎
- Total Pages
  228
- Publisher
  アプタマーによるシグナル伝達の阻害と制癌戦略
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Book] 機能性 Non-coding RNA2006
- Author(s)
  平尾一郎
- Total Pages
  255
- Publisher
  人工塩基対システムの開発 : 機能性RNAの創製を目指して
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Book] バイオニクス2006
- Author(s)
  村上裕, 菅裕明, 平尾一郎
- Total Pages
  92
- Publisher
  セントラルドグマを作り変える
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Book] 日経サイエンス2005
- Author(s)
  平尾一郎
- Total Pages
  140
- Publisher
  汎用性の高い人口塩基対を応用した高機能バイオポリマーの開発
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Book] ゲノムケミストリー2003
- Author(s)
  平尾一郎
- Total Pages
  240
- Publisher
  ポリメラーゼ認識能をもつ人工塩基対
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] DNAの文字を増やす合成生物学―Xenobiologyに向けて2015
- Author(s)
  平尾一郎、木本路子
- Journal Title
  
  生化学
  
  Volume: 87 Pages: 101-111
- NAID
  40020383673
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26248043
[Journal Article] Architecture of high-affinity unnatural-base DNA aptamers toward pharmaceutical applications.2015
- Author(s)
  K. Matsunaga, M. Kimoto, C. Hanson, M. Sanford, H.A. Young, I. Hirao
- Journal Title
  
  Scientific Reports
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26248043
[Journal Article] DNA aptamer generation by genetic alphabet expansion SELEX (EXSELEX) using an unnatural base pair system2015
- Author(s)
  M. Kimoto, K. Matsunaga, I. Hirao
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26248043
[Journal Article] Site-specific labeling of RNA by combining genetic alphabet expansion transcription and copper-free click chemistry.2015
- Author(s)
  T. Someya, A. Ando, M. Kimoto, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: ４３ Pages: 6665-6676
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26248043
[Journal Article] 遺伝情報の拡張とその応用技術2014
- Author(s)
  平尾一郎・木本路子・松永賢一郎
- Journal Title
  
  高分子
  
  Volume: 6月号 Pages: 394-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26248043
[Journal Article] Unnatural base pair systems for sensing and diagnostic applications2011
- Author(s)
  M. Kimoto, R. S. Cox 3rd, I. Hirao
- Journal Title
  
  Expert Rev. Mol. Diagn.
  
  Volume: 11 Pages: 321-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Monitoring the site-specific incorporation of dual fluorophore-quencher base analogues for target DNA detection by an unnatural base pair system. Org2011
- Author(s)
  R. Yamashige, M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Biomol. Chem.
  
  Volume: 412 Pages: 325-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] 人工塩基対の開発によるDNAテクノロジーの進歩2010
- Author(s)
  平尾一郎
- Journal Title
  
  医学の歩み
  
  Volume: 232 Pages: 933-934
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A unique fluorescent base analogue for the expansion of the genetic alphabet2010
- Author(s)
  M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 132 Pages: 4988-4989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific incorporation of extra components into RNA by transcription using unnatural base pair systems2010
- Author(s)
  M. Kimoto, I. Hirao
- Journal Title
  
  Methods, Mol. Biol.
  
  Volume: 634 Pages: 355-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article]2010
- Author(s)
  平尾一郎
- Journal Title
  
  医学のあゆみ、Vol.232, No.9, 人工塩基対の開発によるDNAテクノロジーの進歩(医師薬出版株式会社)
  
  Pages: 933-934
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis2010
- Author(s)
  Y. Hikida, M. Kimoto, S. Yokoyama, I. Hirao
- Journal Title
  
  Nature Protocols
  
  Volume: 5 Pages: 1312-1323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A unique fluorescent base analogue for the expansion of the genetic alphabet2010
- Author(s)
  M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 4988-4989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A new unnatural base pair system between fluorophore and quencher base analogues for nucleic acid-based imaging technology2010
- Author(s)
  M. Kimoto, T. Mitsui, R. Yamashige, A. Sato, S. Yokoyama, I. Hirao
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 132 Pages: 15418-15426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] アプタマーの可能性を広げる合成生物学2009
- Author(s)
  平尾一郎
- Journal Title
  
  Cytometry Research 19(2)
  
  Pages: 9-17
- NAID
  10026084379
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article]2009
- Author(s)
  平尾一郎
- Journal Title
  
  遺伝子医学MOOK15、最新RNAと疾患研究、新規アプタマー創製へのチャレンジ・人工塩基対技術(メディカルドゥ)
  
  Pages: 167-173
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules2009
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] 新規アプタマー創製へのチャレンジ・人工塩基対技術2009
- Author(s)
  平尾一郎
- Journal Title
  
  遺伝子医学MOOK 15
  
  Pages: 167-173
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article]2009
- Author(s)
  平尾一郎
- Journal Title
  
  Protein Engineering, Cell-Free Synthesis of Proteins with Unnatural Amino Acids.The PURE System and Expansion of the Genetic Code(Springer)
  
  Pages: 271-290
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules2009
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res. 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  平尾一郎
- Journal Title
  
  Cytometry Res. 19
  
  Pages: 9-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An efficient unnatural base pair for PCR amplification.2007
- Author(s)
  I.Hirao
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 129 Pages: 15549-15555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] 人工塩基対による遺伝情報の拡張2007
- Author(s)
  平尾一郎
- Journal Title
  
  高分子
  
  Volume: 56 Pages: 191-195
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] 人工塩基対による遺伝情報の拡張技術2007
- Author(s)
  平尾一郎
- Journal Title
  
  化学と生物
  
  Volume: 45 Pages: 672-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] 複製・転写可能な人工塩基対の創出2007
- Author(s)
  平尾一郎
- Journal Title
  
  バイオテクノロジージャーナル
  
  Volume: 1/2 Pages: 79-83
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Fluorescent probing for RNA molecules by an unnatural base-pair system2007
- Author(s)
  M. Kimoto, T. Mitsui, Y. Harada, A. Sato, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 35 Pages: 5360-5369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An efficient unnatural base pair for PCR amplification2007
- Author(s)
  I. Hirao, T. Mitsui, M. Kimoto, S. Yokoyama
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 129 Pages: 15549-15555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Inhibition of the signal transduction and cancer therapy by aptamers.2006
- Author(s)
  I.Hirao
- Journal Title
  
  RNA and drug discovery
  
  Pages: 228-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Development of unnatural base pair systems-toward the creation of novel functional RNA molecules.2006
- Author(s)
  I.Hirao
- Journal Title
  
  Functional non-coding RNA
  
  Pages: 255-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Development of novel functional biopolymers by unnatural base pair systems.2006
- Author(s)
  I.Hirao
- Journal Title
  
  Nikkei-science 5
  
  Pages: 140-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Re-creation of the central dogma.2006
- Author(s)
  H.Murakami, H.Suga, I.Hirao
- Journal Title
  
  Bionics 3
  
  Pages: 92-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Non-hydrogen-bonded base pairs for specific transcription.2005
- Author(s)
  I.Hirao, T.Mitsui, M.Kimoto, R.Kawai, A.Sato, S.Yokoyama
- Journal Title
  
  Nucleic Acids Symp. Ser. 49
  
  Pages: 33-34
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific fluorescent labeling of RNA molecules by specific transcription using unnatural base pairs.2005
- Author(s)
  R.Kawai, M.Kimoto, S.Ikeda, T.Mitsui, M.Endo, S.Yokoyama, J.Hirao
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 17286-17295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific fluorescent labeling of RNA molecules by specific transcription using unnatural base pairs.2005
- Author(s)
  R.Kawai, M.Kimoto, S.Ikeda, T.Mitsui, M.Endo, S.Yokoyama, I.Hirao
- Journal Title
  
  J. Am. Chem. Soc. 127
  
  Pages: 17286-17295
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Fluorescent properties of an unnatural nucleobase, 2-amino-6-(2-thienyl)purine, in DNA and RNA fragments.2005
- Author(s)
  T.Mitsui, M.Kimoto, S.Yokoyama, I.Hirao
- Journal Title
  
  Nucleic Acids Symp. Ser. 49
  
  Pages: 285-286
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] In vitroセレクション〜標的タンパク質に結合するRNAアプタマーの作成〜2005
- Author(s)
  平尾一郎
- Journal Title
  
  生命化学研究レター 19
  
  Pages: 21-25
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific biotinylation of RNA molecules by transcription using unnatural base pairs.2005
- Author(s)
  K.Moriyama, M.Kimoto, T.Mitsui, S.Yokoyama, I.Hirao
- Journal Title
  
  Nucleic Acids Res. 33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] DNA/RNAアプタマー〜その作成から臨床応用まで、2005
- Author(s)
  平尾一郎
- Journal Title
  
  医薬ジャーナル 41
  
  Pages: 2015-2022
- NAID
  40006810988
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific incorporation of fluorescent probes into RNA by specific transcription using unnatural base pairs.2005
- Author(s)
  M.Kimoto, R.Kawai, T.Mitsui, Y.Harada, A.Sato, S.Yokoyama, I.Hirao
- Journal Title
  
  Nucleic Acids Symp. Ser. 49
  
  Pages: 287-288
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] An efficient unnatural base pair for a base-pair-expanded transcription system.2005
- Author(s)
  T.Mitsui, M.Kimoto, Y.Harada, S.Yokoyama, I.Hirao
- Journal Title
  
  J. Am. Chem. Soc 127
  
  Pages: 8652-8658
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] DNA/RNA aptamers : from preparation to pharmaceutical applications.2005
- Author(s)
  I.Hirao
- Journal Title
  
  Iyaku J. 41
  
  Pages: 2015-2022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific biotinylation of RNA molecules by transcription using unnatural base pairs.2005
- Author(s)
  K.Moriyama, M.kimoto, T.Mitsui, S.Yokoyama, I.Hirao
- Journal Title
  
  Nucleic Acids Res. 33
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] In vitro selection-Preparation of RNA aptamers that bind to target proteins.2005
- Author(s)
  I.Hirao
- Journal Title
  
  Forum of Biomol.Chem.Lett. 19
  
  Pages: 21-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] DNA/RNA アプタマー-その作成から臨床応用まで-2005
- Author(s)
  平尾一郎
- Journal Title
  
  医薬ジャーナル 41
  
  Pages: 2015-2022
- NAID
  40006810988
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific fluorescent labeling of RNA molecules by specific transcription using unnatural base pairs.2005
- Author(s)
  R.Kawai, M.Kimoto, S.Ikeda, T.Mitsui, M.Endo, S.Yokoyama, I.Hirao
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 17286-17295
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] In vitro セレクション-標的タンパク質に結合するRNAアプタマーの作成-2005
- Author(s)
  平尾一郎
- Journal Title
  
  生命化学研究レター 19
  
  Pages: 21-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] An efficient unnatural base pair for a base-pair-expanded transcription system.2005
- Author(s)
  T.Mitsui, M.Kimoto, Y.Harada, S.Yokoyama, I.Hirao
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 8652-8658
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs between 2- and 6-substituted purines and 2-oxo(1H)pyridine for expansion of the genetic alphabet.2004
- Author(s)
  I.Hirao, T.Fujiwara, M.Kimoto, S.Yokoyama
- Journal Title
  
  Bioorg.Med.Chem.Soc. 14
  
  Pages: 4887-4890
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs between 2- and 6-substituted purines and 2- oxo(1H)pyridine for expansion of the genetic alphabet.2004
- Author(s)
  I.Hirao, T.Fujiwara, M.Kimoto, S.Yokoyama
- Journal Title
  
  Bioorg. Me. Chem. Lett. 14
  
  Pages: 4887-4890
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] A quantitative, non-radioactive single-nucleotide insertion assay for analysis of DNA replication fidelity by using an automated DNA sequencer.2004
- Author(s)
  M.Kimoto, S.Yokoyama, I.Hirao
- Journal Title
  
  Biotechnol.Lett. 26
  
  Pages: 999-1005
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] A two-unnatural-base-pair system toward the expansion of the genetic code.2004
- Author(s)
  I.Hirao, Y.Harada, M.Kimoto, T.Mitsui, T.Fujiwara, S.Yokoyama
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 13298-13305
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] In vitro selection of RNA aptamers that bind to colicin E3 and structurally resemble the decoding site of 16S ribosomal RNA.2004
- Author(s)
  I.Hirao, Y.Harada, T.Nojima, Y.Osawa, H.Masaki, S.Yokoyama
- Journal Title
  
  Biochemistry 43
  
  Pages: 3214-3221
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] A quantitative, non-radioactive single-nucleotide insertion assay for analysis of DNA replication fidelity by using an automated DNA sequencer.2004
- Author(s)
  K.Michiko, S.Yokoyama, I.Hirao
- Journal Title
  
  Biotechnol. Lett. 26
  
  Pages: 999-1005
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] A two-unnatural-base-pair system toward the expansion of the genetic code.2004
- Author(s)
  I.Hirao, Y.Harada, M.Kimoto, T.Mitsui, T.Fujiwara, S.Yokoyama
- Journal Title
  
  J. Am. Chem. Soc. 126
  
  Pages: 13298-13305
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific incorporation of a photo-crosslinking component into RNA by T7 transcription mediated by unnatural base pairs.2004
- Author(s)
  M.kimoto, M.Endo, T.Mitsui, T.Okuni, I.Hirao, S.Yokoyama
- Journal Title
  
  Chem. Biol. 11
  
  Pages: 47-55
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs mediate the site-specific incorporation of an unnatural hydrophobic component into RNA transcripts.2004
- Author(s)
  M.Endo, T.Mitsui, T.Okuni, M.Kimoto, I.Hirao, S.Yokoyama
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 2593-2596
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific fluorescent labeling of RNA by a base-pair expanded transcription system.2004
- Author(s)
  R.Kawai, M.Kimoto, T.Mitsui, S.Yokoyama, I.Hirao
- Journal Title
  
  Nucleic Acids Symp.Ser. 48
  
  Pages: 35-36
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] A quantitative, non-radioactive single-nucleotide insertion assay for analysis of DNA replication fidelity by using an automated DNA sequencer.2004
- Author(s)
  K.Michiko, S.Yokoyama, I.Hirao
- Journal Title
  
  Biotechnology Lett. 26
  
  Pages: 999-1005
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] A two-unnatural-base-pair system toward the expansion of the genetic code.2004
- Author(s)
  I.Hirao, Y.Harada, M.Kimoto, T.Mitsui, T.Fuiiwara, S.Yokoyama
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 13298-13305
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs between 2- and 6-substituted purines and 2-oxo(1H)pyridine for expansion of the genetic alphabet.2004
- Author(s)
  I.Hirao, T.Fujiwara, M.Kimoto, S.Yokoyama
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 4887-4890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs mediate the site-specific incorporation of an unnatural hydrophobic component into RNA transcripts.2004
- Author(s)
  M.Endo, T.Mitsui, T.Okuni, M.Kimoto, I.Hirao, S.Yokoyama
- Journal Title
  
  Bioorg.Med.Chem.Soc. 14
  
  Pages: 2593-2596
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Site-specific incorporation of a photo-crosslinking component into RNA by T7 transcription mediated by unnatural base pairs.2004
- Author(s)
  M.Kimoto, M.Endo, T.Mitsui, T.Okuni, I.Hirao, S.Yokoyama
- Journal Title
  
  Chem.Biol. 11
  
  Pages: 47-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs mediate the site-specific incorporation of an unnatural hydrophobic component into RNA transcripts.2004
- Author(s)
  M.Endo, T.Mitsui, T.Okuni, M.Kimoto, I.Hirao, S.Yokoyama
- Journal Title
  
  Bioorg. Med. Chem. Lett. 14
  
  Pages: 2593-2596
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] An unnatural hydrophobic base, 4-propynylpyrrole-2-carbaldehyde, as an efficient pairing partner of 9-methylimidazo[(4, 5)-b]pyridine.2003
- Author(s)
  M.Mitsui, M.Kimoto, A.Sato, S.Yokoyama, I.Hirao
- Journal Title
  
  Bioorg.Med.Chem.Lett. 13
  
  Pages: 4515-4518
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] An unnatural hydrophobic base pair with shape complementarity between pyrrole-2-carbaldehyde and 9-methylimidazo[(4,5)-b]pyridine.2003
- Author(s)
  T.Mitsui, A.Kitamura, M.Kimoto, T.To, A.Sato, I.Hirao, S.Yokoyama
- Journal Title
  
  J. Am. Chem. Soc. 125
  
  Pages: 5298-5307
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Unnatural base pairs capable of being recognized by polymerases.2003
- Author(s)
  I.Hirao
- Journal Title
  
  Genome Chemistry
  
  Pages: 240-240
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Creation of extra-terrestrial genetic materials.2003
- Author(s)
  I.Hirao
- Journal Title
  
  Chem.Edu. 51
  
  Pages: 410-413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Creation of artificial genes.2003
- Author(s)
  I.Hirao, S.Yokoyama
- Journal Title
  
  Tanpakushitsu Kakusan Koso 48
  
  Pages: 1496-1502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] 新規遺伝子の人工創製2003
- Author(s)
  平尾一郎, 横山茂之
- Journal Title
  
  蛋白質・核酸・酵素 48
  
  Pages: 1496-1502
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] 新しい医薬 : 核酸アプタマー2003
- Author(s)
  平尾一郎, 木本路子
- Journal Title
  
  バイオマテリアル・生体材料 21
  
  Pages: 270-277
- NAID
  10011629707
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Novel therapeutic and diagnostic reagents : nucleic acid aptamers.2003
- Author(s)
  I.Hirao, M.Kimoto
- Journal Title
  
  J.Jpn.Soc.Biomaterials 21
  
  Pages: 270-277
- NAID
  10011629707
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] An unnatural hydrophobic base pair with shape complementarity between pyrrole-2-carbaldehyde and 9-methylimidazo[(4, 5)-b]pyridine.2003
- Author(s)
  M.Mitsui, A.Kitamura, M.Kimoto, T.To, A.Sato, I.Hirao, S.Yokoyama
- Journal Title
  
  J.Am.Chem.Soc. 125
  
  Pages: 5298-5307
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] An unnatural hydrophobic base, 4-propynylpyrrole-2-carbaldehyde, as an efficient pairing partner of 9-methylimidazo[(4,5)-b]pyridine.2003
- Author(s)
  T.Mitsui, M.Kimoto, A.Sato, S.Yokoyama, I.Hirao
- Journal Title
  
  Bioorg. Med. Chem. Lett. 13
  
  Pages: 4515-4518
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] "宇宙人"の遺伝子を作る2003
- Author(s)
  平尾一郎
- Journal Title
  
  化学と教育 51
  
  Pages: 410-413
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Placing extra components into RNA by specific transcription using unnatural base pair systems.
- Author(s)
  I.Hirao
- Journal Title
  
  Bio Texhniques (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Expansion of the genetic information by using artificial base pairs.
- Author(s)
  I.Hirao
- Journal Title
  
  Tanpakushitsu Kakusan Koso (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Natural vs artificial creation of base pairs in DNA : origin of nucleobases from the perspectives of unnatural base pair studies
- Author(s)
  I. Hirao, M. Kimoto, R. Yamashige
- Journal Title
  
  Acc. Chem. Res.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Highly specific unnatural base pair systems as a third base pair for PCR amplification
- Author(s)
  R. Yamashige, M. Kimoto, Y. Takezawa, A. Sato, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis
- Author(s)
  Y. Hikida, M. Kimoto, S. Yokoyama, I. Hirao
- Journal Title
  
  Nature Protocols (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] 人工塩基対による遺伝情報の拡張
- Author(s)
  平尾一郎
- Journal Title
  
  蛋白質・核酸・酸素 (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Journal Article] Placing extra components into RNA by specific transcription using unnatural base pair systems.
- Author(s)
  I.Hirao
- Journal Title
  
  BioTechniques (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 人工塩基を含むライブラリーを用いた機能性核酸の製造方法2011
- Inventor(s)
  平尾一郎、平尾路子、山重りえ、横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2011-253357
- Filing Date
  2011-11-18
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 核酸アプタマーの作成方法2011
- Inventor(s)
  平尾一郎、平尾路子、横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2011-117122
- Filing Date
  2011-08-12
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 消光性ならびに蛍光性の塩基類似体とその利用2010
- Inventor(s)
  平尾一郎、平尾路子、横山茂之、三井雅雄、山重りえ
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2010-098319
- Filing Date
  2010-04-19
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 新規な核酸塩基対2010
- Inventor(s)
  平尾一郎、石川正英、藤原健志、横山茂之
- Industrial Property Rights Holder
  科学技術振興機構
- Acquisition Date
  2010-02-23
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 機能性核酸の安定化法2010
- Inventor(s)
  平尾一郎、平尾路子、劉爽、野澤厳
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2010-096520
- Filing Date
  2010-04-19
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 消光性ならびに蛍光性の核酸塩基類似体とその応用2010
- Inventor(s)
  平尾一郎、平尾路子、横山茂之、三井雅雄
- Industrial Property Rights Holder
  理化学研究所、タグシクスバイオ株式会社
- Industrial Property Number
  2010-098319
- Filing Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 機能性核酸の安定化2010
- Inventor(s)
  平尾一郎、平尾路子、劉爽、野澤巌
- Industrial Property Rights Holder
  理化学研究所、タグシクスバイオ株式会社
- Industrial Property Number
  2010-096520
- Filing Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 新規蛍光性人工塩基対2009
- Inventor(s)
  平尾一郎, 平尾路子, 横山茂之, 三井雅雄
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2009-232776
- Filing Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 新規蛍光性人工塩基対2009
- Inventor(s)
  平尾一郎、平尾路子、三井雅雄、横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2009-232776
- Filing Date
  2009-10-06
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] イミダゾピリジン誘導体2009
- Inventor(s)
  平尾一郎、横山茂之
- Industrial Property Rights Holder
  理化学研究所
- Acquisition Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 特異な塩基対を形成する人工塩基対2009
- Inventor(s)
  平尾一郎、平尾路子、横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2009-232851
- Filing Date
  2009-10-06
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 特異な塩基対を形成する人工塩基対2009
- Inventor(s)
  平尾一郎, 平尾路子, 横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2009-232851
- Filing Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 新規蛍光性人工塩基2009
- Inventor(s)
  平尾一郎、平尾路子、横山茂之、三井雅雄
- Industrial Property Rights Holder
  理化学研究所、タグシクスバイオ株式会社
- Industrial Property Number
  2009-232776
- Filing Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 高選択・高効率でPCR増幅が可能な新規DNA2008
- Inventor(s)
  平尾一郎、平尾路子、横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクス・バイオ株式会社
- Industrial Property Number
  2008-094255
- Filing Date
  2008-03-31
- Overseas
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] イミダゾピリミジン誘導体2005
- Inventor(s)
  平尾一郎, 横山茂之
- Industrial Property Rights Holder
  東京大学, 理化学研究所
- Filing Date
  2005-01-20
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 抗がん剤2005
- Inventor(s)
  平尾, 横山
- Industrial Property Rights Holder
  理化学研究所, 東京大学
- Patent Publication Number
  2005-232079
- Filing Date
  2005-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 新規人工塩基対及びその利用2005
- Inventor(s)
  平尾, 横山
- Industrial Property Rights Holder
  理化学研究所, 東京大学
- Industrial Property Number
  2005-226492
- Filing Date
  2005-08-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 核酸の複製の方法及び新規人工塩基対2005
- Inventor(s)
  平尾, 横山
- Industrial Property Rights Holder
  理化学研究所, 東京大学
- Industrial Property Number
  2005-356883
- Filing Date
  2005-12-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] イミダゾピリジン誘導体2005
- Inventor(s)
  平尾, 横山
- Industrial Property Rights Holder
  理化学研究所
- Industrial Property Number
  2005-012585
- Filing Date
  2005-01-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 新規人工塩基対及びその利用2005
- Inventor(s)
  平尾一郎, 横山茂之
- Industrial Property Rights Holder
  東京大学, 理化学研究所
- Industrial Property Number
  2005-226492
- Filing Date
  2005-08-04
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 核酸の複製の方法及び新規人工塩基対2005
- Inventor(s)
  平尾一郎, 横山茂之
- Industrial Property Rights Holder
  東京大学, 理化学研究所
- Industrial Property Number
  2005-356883
- Filing Date
  2005-12-09
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 非天然型塩基を有するヌクレオシド又はヌクレオチド及びその利用2005
- Inventor(s)
  平尾, 横山
- Industrial Property Rights Holder
  理化学研究所, 東京大学
- Filing Date
  2005-03-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Patent] 新規なヌクレオチド若しくはヌクレオチド誘導体及びその利用2005
- Inventor(s)
  平尾, 横山
- Industrial Property Rights Holder
  理化学研究所, 東京大学
- Filing Date
  2005-11-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350097
[Presentation] 人工塩基対技術による高機能核酸医薬品の創出2015
- Author(s)
  I. Hirao
- Organizer
  千里ライフサイエンス新適塾
- Place of Presentation
  大阪、千里ライフサイエンスセンタービル
- Year and Date
  2015-07-29
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Creation of a Genetic Alphabet Expansion System Using Unnatural Base Pairs and its Applications Toward Diagnostics and Therapeutics2015
- Author(s)
  I. Hirao
- Organizer
  Institute of Bioengineering and Nanotechnology Seminar
- Place of Presentation
  Singapore, Biopolis
- Year and Date
  2015-05-05
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Genetic alphabet expansion by unnatural base pair systems and its diagnostic and therapeutic applications2015
- Author(s)
  I. Hirao
- Organizer
  日本分子生物学会年会（BMB2015）
- Place of Presentation
  神戸、ポートアイランド
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Unnatural-Base DNA Aptamers Targeting VEGF165 toward Diagnostics and Therapeutics2015
- Author(s)
  M. Kimoto, I. Hirao
- Organizer
  日本分子生物学会年会（BMB2015）
- Place of Presentation
  神戸、ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Unnatural-Base DNA Aptamers Targeting VEGF165 toward Diagnostics and Therapeutics2015
- Author(s)
  M. Kimoto, K. Matsunaga, M. Nakamura, I. Hirao
- Organizer
  ISNAC2015 第４２回国際核酸化学シンポジウム
- Place of Presentation
  姫路、イーグレひめじ
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Genetic alphabet expansion by an unnatural base pair system toward diagnostic and therapeutic applications using xeno-nucleic acids2015
- Author(s)
  I. Hirao
- Organizer
  IHES Conference
- Place of Presentation
  France, Bures-sur-Yvette
- Year and Date
  2015-12-14
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Creation of high affinity DNA aptamers using a genetic alphabet expansion toward diagnostic and therapeutic applications2015
- Author(s)
  I. Hirao
- Organizer
  Pachifichem 2015
- Place of Presentation
  USA, Hawaii
- Year and Date
  2015-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Creation of unnatural bases pairs and their application to DNA aptamers2015
- Author(s)
  I. Hirao
- Organizer
  RIKEN Symposium
- Place of Presentation
  神戸、理研
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] High Affinity DNA Aptamers by a genetic alphabet expansion as an antibody drug candidate2015
- Author(s)
  I. Hirao
- Organizer
  VIB Conference
- Place of Presentation
  Belgium, Gent
- Year and Date
  2015-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] インターフェロンγに特異的に結合する人工塩基DNAアプタマー技術2015
- Author(s)
  I. Hirao
- Organizer
  第８０回日本インターフェロン•サイトカイン学会
- Place of Presentation
  東京、東工大大岡山キャンパス
- Year and Date
  2015-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] New biotechnology by the expansion of the genetic alphabet using unnatural base pairs2011
- Author(s)
  I. Hirao
- Organizer
  European Genomics-2011 Meeting
- Place of Presentation
  Rome/Italy
- Year and Date
  2011-10-11
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Fluorescently unique unnatural base pairs for the expansion of the genetic alphabet2011
- Author(s)
  I. Hirao
- Organizer
  XVth symposium on chemistry of nucleic acid components
- Place of Presentation
  Cesky Krumlov, Czech
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems for DNA/RNA biotechnology.2010
- Author(s)
  Ichiro Hirao
- Organizer
  Pachifichem 2010
- Place of Presentation
  米国・ハワイ
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural Base Pair Systems for Diagnostic Applications2010
- Author(s)
  I. Hirao
- Organizer
  TIDES : 2010
- Place of Presentation
  Boston, USA
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 核酸の起源:非天然型ヌクレオチドの可能性2010
- Author(s)
  平尾一郎
- Organizer
  BMB2010 第33回日本分子生物学会年会・第63回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural Base Pair Systems for the Expansion of the Genetic Alphabet2010
- Author(s)
  I. Hirao
- Organizer
  IRT2010 : International Roundtable on NNN
- Place of Presentation
  Lyon/France
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対技術による標的遺伝子の検出2010
- Author(s)
  平尾一郎
- Organizer
  第231回液体クロマトグラフィー研究懇談会
- Place of Presentation
  東京
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural Base Pair Systems for the Expansion of the Genetic Alphabet.2010
- Author(s)
  Ichiro Hirao
- Organizer
  IRT2010 : International Roundtable on NNN
- Place of Presentation
  フランス・リヨン
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural base pairs for the expansion of the genetic alphabet.2010
- Author(s)
  Ichiro Hirao
- Organizer
  EVOLVING DNA POLYMERASES : CHEMISTRY MEETS BIOLOGY
- Place of Presentation
  スイス・モンテヴェリタ
- Year and Date
  2010-05-11
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] DNAの文字を増やす:人工塩基対の創出2010
- Author(s)
  平尾一郎
- Organizer
  日本生化学会北陸支部第28回大会
- Place of Presentation
  福井
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 核酸塩基の起源-人工塩基対の創出2010
- Author(s)
  平尾一郎
- Organizer
  日本進化学会第12回東京大会
- Place of Presentation
  東京
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems for DNA/RNA biotechnology2010
- Author(s)
  I. Hirao
- Organizer
  Pachifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural Base Pair Systems for Diagnostic Applications.2010
- Author(s)
  Ichiro Hirao
- Organizer
  TIDES : 2010
- Place of Presentation
  米国・ボストン
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural base pairs for the expansion of the genetic alphabet2010
- Author(s)
  I. Hirao
- Organizer
  Evolving DNA Polymerases : Chemistry Meets Biology
- Place of Presentation
  Monte Verita/Switzerland
- Year and Date
  2010-05-11
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 遺伝情報の拡張を目指した人工塩基対の開発2010
- Author(s)
  平尾一郎
- Organizer
  産総研ゲノムファクトリー:異分野ネットワーク
- Place of Presentation
  札幌
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural base pair systems toward new biotechnology2009
- Author(s)
  Ichiro Hirao
- Organizer
  ASIA TIDE
- Place of Presentation
  東京
- Year and Date
  2009-02-23
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural base pair systems toward new biotechnology2009
- Author(s)
  Ichiro Hirao
- Organizer
  ACS 237th National Meeting
- Place of Presentation
  米国ユタ
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural base pair systems toward new biotechnology2009
- Author(s)
  I. Hirao
- Organizer
  ACS 237th National Meeting
- Place of Presentation
  Utah/USA
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems toward nucleic acid technologies2009
- Author(s)
  平尾一郎
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] The development of unnatural base pair systems for expansion of the genetic alphabet2008
- Author(s)
  I.Hirao
- Organizer
  XIVth symposium on chemistry of nucleic acid components
- Place of Presentation
  Czech Republic
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems for DNA/RNA-based biotechnology2008
- Author(s)
  Ichiro Hirao
- Organizer
  TIDE
- Place of Presentation
  米国ラスベガス
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems for DNA/RNA-based biotechnology2008
- Author(s)
  I. Hirao
- Organizer
  TIDES : 2008, IBC's 4th International Nucleic Acids Technologies for Diagnostics
- Place of Presentation
  Las Vegas/USA
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Expansion of the genetic alphabet by unnatural base pair systems2008
- Author(s)
  I.Hirao
- Organizer
  Organic Chemistry Seminar in Stanford
- Place of Presentation
  Stanford University
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural base pair systems toward new biotechnology2008
- Author(s)
  I. Hirao
- Organizer
  ACS 237th National Meeting
- Place of Presentation
  Philadelphia/USA
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] アプタマーの可能性を広げる合成生物学2008
- Author(s)
  平尾一郎
- Organizer
  第18回日本サイトメトリー学会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] The development of unnatural base pair systems for expansion of the genetic alphabet2008
- Author(s)
  I. Hirao
- Organizer
  XIVth symposium on chemistry of nucleic acid components
- Place of Presentation
  Cesky Krumlov, Czech
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Efficient PCR amplification by an unnatural base pair system2008
- Author(s)
  I.Hirao
- Organizer
  ACS 236th National Meeting
- Place of Presentation
  Philadelphia
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対システムの創製2008
- Author(s)
  平尾一郎
- Organizer
  日本生物工学会北日本支部札幌シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems for DNA/RNA-based biotechnology2008
- Author(s)
  I.Hirao
- Organizer
  TIDES Oligonucleotide and peptide
- Place of Presentation
  Las Vegas
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Unnatural base pair systems for expansion of the genetic alphabet2008
- Author(s)
  Ichiro Hirao
- Organizer
  ACS 236th National Meeting
- Place of Presentation
  米国フィラデルフィア
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対による遺伝情報の拡張2007
- Author(s)
  平尾一郎
- Organizer
  平成19年度バイオ・高分子研究会
- Place of Presentation
  蒲郡
- Year and Date
  2007-09-22
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] セントラルドグマのケミカルバイオテクノロジー2007
- Author(s)
  平尾一郎
- Organizer
  グローバルCOE物質科学イノベーション講演会
- Place of Presentation
  札幌
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] セントラルドグマの合成生物学-人工塩基対の創製2007
- Author(s)
  平尾一郎
- Organizer
  名古屋大学遺伝子実験施設公開セミナー
- Place of Presentation
  名古屋
- Year and Date
  2007-12-19
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of an unnatural base pair for efficient PCR amplification.2007
- Author(s)
  平尾一郎
- Organizer
  第5回国際核酸化学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対の開発と創薬への応用2007
- Author(s)
  平尾一郎
- Organizer
  第49回今掘フォーラム
- Place of Presentation
  東京
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対による遺伝情報の拡張2007
- Author(s)
  平尾一郎
- Organizer
  ケミカルバイオロジー研究勉強会
- Place of Presentation
  埼玉
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Generation of high affinity DNA aptamers using a genetic alphabet expansion toward diagnostic and therapeutic applications
- Author(s)
  Ichiro Hirao
- Organizer
  66th Indian Pharmaceutical Congress
- Place of Presentation
  Hyderabad, India
- Year and Date
  2015-01-23 – 2015-01-25
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] New approach for nucleic acid diagnostics and therapeutics
- Author(s)
  Ichiro Hirao
- Organizer
  Nucleic Acid Workshop
- Place of Presentation
  Colorado, USA
- Year and Date
  2014-07-28 – 2014-08-01
- Invited
- Data Source
  KAKENHI-PROJECT-26248043
[Presentation] Site-specific enzymatic incorporation of extra components into functional DNA and RNA molecules by genetic alphabet expansion
- Author(s)
  Ichiro Hirao
- Organizer
  Fluorescent Biomolecules and their Building Blocks - Design and Applications
- Place of Presentation
  CA, USA
- Year and Date
  2014-08-06 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-26248043

1. MITSUI Tsuneo (60345155)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. MIURA Kin-ichiro (30000227)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KUMAGAI Izumi (10161689)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KIMOTO Michiko (20415144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
5. 渡辺公綱 (00134502)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KAWAI Rie (10415135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. IKEDA Shuji (80336320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 森山圭 (60345163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

HIRAO Ichiro 平尾 一郎

HIRANO Ichiro 平尾 一郎

平尾 一郎 ヒラオ イチロウ

Research Projects

Research Products

Co-Researchers

人工塩基対による遺伝情報の拡張技術の細胞システムへの応用Principal Investigator

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Creation of highly-functional nucleic acids by unnatural base pair systemsPrincipal Investigator

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Creation of extra base pairs for the development of novel functional nucleic acidsPrincipal Investigator

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安定なヘアピン様構造を形成するRNA断片の合成と構造解析Principal Investigator

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一本鎖DNAとして特殊構造を示すDNA配列とタンパク質の特異的相互作用Principal Investigator

Principal Investigator

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一本鎖DNAとして特殊構造を示すDNA配列とタンパク質の特異的相互作用Principal Investigator

Principal Investigator

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異常に安定なDNAのミニヘアピン構造とタンパク質との特異的相互作用Principal Investigator

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人工的タンパク質合成系の研究

Principal Investigator

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人工的タンパク質合成系の研究

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Relationship between efficiency of protein synthesis and structure of messenger RNA

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[Book] Synthetic Biology (Synthetic Genetic Polymers Functioning to Store and Propagate Information by Genetic alphabet expansion.)2015

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[Book] The Chemical Biology of Nucleic Acids (Creation of Unnatural Base Pair Systems Toward New DNA/RNA Biotechnologies.)2014

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[Book] 核酸化学のニュートレンド2011

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[Book] 核酸実験の原理とプロトコール2011

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[Book] 医学のあゆみ2011

HIRAO Ichiro 平尾一郎

HIRANO Ichiro 平尾一郎

平尾一郎ヒラオイチロウ