Yoshimura Teizo 吉村禎造

Researcher Number	50174991
Affiliation (Current)	2025: 岡山大学, 医歯薬学総合研究科, 非常勤研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 岡山大学, 医歯薬学総合研究科, 非常勤研究員 2018 – 2019: 岡山大学, 医歯薬学総合研究科, 准教授
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 白血球遊走因子レセプター / 乳がん / 白血球遊走因子 / 乳癌 / ケモカイン / がん微小環境 / 腫瘍免疫 / 臓器移植 / ケモカインレセプター / Formylpeptide receptor … More / Leukocytes / Tumor microenvironment / Chemoattractant receptor / Chemoattractant / Breast cancer / がん転移 / Formylpeptideレセプター / 遊走因子レセプター / 白血球 / 血管新生 / 好中球 / 線維芽細胞 / マクロファージ / マウスモデル … More Except Principal Investigator 低分子医薬 / がん幹細胞性 / 上皮間葉系移行 / SPFED2 / 低分子医療 / Spred2 / 炎症とがん / シグナル伝達・抑制 / オートファジー / がん / ERK-MAPK / SPRED2 / 微小腫瘍環境 / がん肝細胞性 / 上皮間葉移行 / 内因性抑制因子 / シグナル伝達 Less

Analysis of the mechanisms by which FPRs play a role in the immune regulation against cancer and organ transplantation and its application to treatmentsPrincipal Investigator
- Principal Investigator
  
  吉村禎造
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Okayama University
Role of Spred2 in the pathogenesis of cancer and its application for cancer thepapy
- Principal Investigator
  
  MATSUKAWA AKIHIRO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Okayama University
Inhibition of formylpeptide receptors for treatment of breast cancerPrincipal Investigator
- Principal Investigator
  
  Yoshimura Teizo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Okayama University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells2023
- Author(s)
  Gao T, Yang X, Fujisawa M, Ohara T, Wang T, Tomonobu N, Sakaguchi M, Yoshimura T, Matsukawa A
- Journal Title
  
  Int J Mol Sci
  
  Volume: 24 Issue: 5 Pages: 4996-4996
- DOI
  10.3390/ijms24054996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19562, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-21H02988, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923
[Journal Article] The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis2023
- Author(s)
  Yoshimura Teizo、Li Chunning、Wang Yuze、Matsukawa Akihiro
- Journal Title
  
  Cellular & Molecular Immunology
  
  Volume: 20 Issue: 7 Pages: 714-738
- DOI
  10.1038/s41423-023-01013-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19562, KAKENHI-PROJECT-21H02988
[Journal Article] Spred2 controls the severity of Concanavalin A-induced liver damage by limiting interferon-gamma production by CD4+ and CD8+ T cells2021
- Author(s)
  Sun C, Fujisawa M, Ohara T, Liu Q, Cao C, Yang X, Yoshimura T, Kunkel SL, Matsukawa A.
- Journal Title
  
  J Adv Res
  
  Volume: 35 Pages: 71-86
- DOI
  10.1016/j.jare.2021.03.014
- NAID
  120007183228
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02988
[Journal Article] Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder2021
- Author(s)
  Oda S, Fujisawa M, Chunning L, Ito T, Yamaguchi T, Yoshimura T, Matsukawa A.
- Journal Title
  
  PLoS One
  
  Volume: 16(11) Issue: 11 Pages: e0254289-e0254289
- DOI
  10.1371/journal.pone.0254289
- NAID
  120007192061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02988
[Journal Article] Cancer cell-derived granulocyte-macrophage colony-stimulating factor Is dispensable for the progression of 4T1 murine breast cancer2020
- Author(s)
  Yoshimura, T., Nakamura, K., Li, Chunning, Fujisawa, M, Shiina, T, Imamura, M., Li, T., Mukaida, N., Matsukawa, A.
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 20 Issue: 24 Pages: 1-13
- DOI
  10.3390/ijms20246342
- NAID
  120006816648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08571
[Presentation] ホストのSpred2欠損は、マウスの乳がんモデルにおけるがんの進行を抑制する2024
- Author(s)
  Miao Tian、吉村禎造、李春寧、大原利章、藤澤真義、松川昭博
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] SPRED2 promotes autophagy via mTORC1 signaling pathway in hepatocellular carcinom2024
- Author(s)
  Tianyi Wang, Tong Gao, Toshiaki Ohara, Masayoshi Fujisawa, Teizo Yoshimura, Akihiro Matsukawa
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] SPRED2の欠損はマウスの腫瘍においてオートファジーとマイトファジーを抑制する2024
- Author(s)
  王天一、高桐、藤澤真義、大原利章、吉村禎造、松川昭博
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] マウス閉塞性細気管支炎モデルにおける Formyl peptide receptor (Fpr)の役割解明2024
- Author(s)
  中村薫、大原利章、吉村禎造、松川昭博
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K08070
[Presentation] Spred2 deficiency in the host suppresses the progression of cancer in mouse breast cancer models2024
- Author(s)
  Miao TIAN, Teizo Yoshimura, Chunning Li, Toshiaki Ohara, Masayoshi Fujisawa, Akihiro Matsukawa
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] SPRED2は食道がん細胞のマクロファージをエクソソームのIL-6/STAT3を介して、M2表現形に変化させる2023
- Author(s)
  高桐、田ミョウ、藤澤真義、大原利章、王天偉、李春寧、王宇沢、トウンティンダニン、吉村禎造、松川昭博
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] 腫瘍環境のSpred2欠損は乳がんの増殖と転移を抑制する2023
- Author(s)
  Tian Miao、吉村禎造、李春寧、大原利章、藤澤真義、松川昭博
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] HCC細胞のオートファジーにおけるSpred2の機能及びmTORC1活性化との関係2023
- Author(s)
  王天偉、高桐、藤澤真義、大原利章、吉村禎造、松川昭博
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] HCC細胞のオートファジーにおけるSpred2の機能及びmTOR活性化との関係2022
- Author(s)
  Tianyi Wang, Tong Gao, Masayoshi Fujisawa, Toshiaki Ohara, Teizo Yoshimura, Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] 肺腺癌におけるSpred2の発現と増殖・浸潤の関係2022
- Author(s)
  Yoko Ota, Gao Tong, Sumardika I Wayan, Masayoshi Fujisawa, Teizo Yoshimura, Masakiyo Sakaguchi and Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] 肺腺癌におけるSpred2の発現と増殖・浸潤の関係2022
- Author(s)
  Yoko Ota, Gao Tong, Sumardika I Wayan, Masayoshi Fujisawa, Teizo Yoshimura, Masakiyo Sakaguchi, Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] HCC細胞のオートファジーにおけるSpred2の機能及びmTOR活性化との関係2022
- Author(s)
  Tianyi Wang, Tong Gao, Masayoshi Fujisawa, Toshiaki Ohara, Teizo Yoshimura,Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] Spred2 downregulates cancer stemness in HCC cells, targeting on miR-506-3p and its downstream KLF4.2022
- Author(s)
  Tong Gao, Sahio Ito, Masahiro Fujisawa, Toshiaki Ohara, Teizo Yoshimura, Tianyi Wang, Akihiro Matsukawa
- Organizer
  第51回日本免疫学会総会・学術総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] Spred2 は部分的にmiR-506-3p/KLF4/Stat3シグナルをターゲットとしてHCCにおいて幹細胞性を制御する2022
- Author(s)
  Tong Gao, Sachio Ito, Aye Moh Moh Aung, Masahiro Fujisawa, Toshiaki Ohara, Teizo Yoshimura, Tianyi Wang, Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] Spred2 regulates cancer stemness in HCC cells, targeting on miR-506-3p and its downstream KLF42021
- Author(s)
  Tong Gao, Aye Moh Moh Aung, Masahiro Fujisawa, Toshiaki Ohara, Teizo Yoshimura, Sachio Ito, Akihiro Matsukawa
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] 肺腺癌におけるSpred2の発現の検討と増殖、浸潤との関連2021
- Author(s)
  太田陽子、藤澤真義、吉村禎造、IWayan Ｓ、しえん和彦、阪口政清、豊岡伸一、松川昭博
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] 腫瘍環境のSpred2欠損は4T1乳がん細胞の増殖と転移を抑制する2021
- Author(s)
  Miao Tian、吉村禎造、李春寧、大原利章、藤澤真義、松川昭博
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] HCC細胞のオートファジーにおけるSpred2の役割とERK活性化との関係2021
- Author(s)
  王天一、藤澤真義、大原利章、吉村禎造、高桐、松川昭博
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] Spred2はHCCで幹細胞性をmiR-506-3pによって一部負に抑制する2021
- Author(s)
  高桐、藤澤真義、大原利章、吉村禎造、王天一、伊藤佐智夫、松川昭博
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] Formylpeptide receptor 2 (Fpr2)-deficiency in Non-tumor Cells Decreases Lung Metastasis of 4T1 Murine Breast Cancer Cells2019
- Author(s)
  吉村禎造
- Organizer
  日本病理学会
- Data Source
  KAKENHI-PROJECT-18K08571

1. MATSUKAWA AKIHIRO (90264283)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. 伊藤嘉浩 (40192497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 宮武秀行 (50291935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 阪口政清 (70379840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Yoshimura Teizo 吉村 禎造

Research Projects

Research Products

Co-Researchers

Analysis of the mechanisms by which FPRs play a role in the immune regulation against cancer and organ transplantation and its application to treatmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Spred2 in the pathogenesis of cancer and its application for cancer thepapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inhibition of formylpeptide receptors for treatment of breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spred2 controls the severity of Concanavalin A-induced liver damage by limiting interferon-gamma production by CD4+ and CD8+ T cells2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Cancer cell-derived granulocyte-macrophage colony-stimulating factor Is dispensable for the progression of 4T1 murine breast cancer2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] ホストのSpred2欠損は、マウスの乳がんモデルにおけるがんの進行を抑制する2024

Author(s)

Organizer

Data Source

[Presentation] SPRED2 promotes autophagy via mTORC1 signaling pathway in hepatocellular carcinom2024

Author(s)

Organizer

Data Source

[Presentation] SPRED2の欠損はマウスの腫瘍においてオートファジーとマイトファジーを抑制する2024

Author(s)

Organizer

Data Source

[Presentation] マウス閉塞性細気管支炎モデルにおける Formyl peptide receptor (Fpr)の役割解明2024

Author(s)

Organizer

Data Source

[Presentation] Spred2 deficiency in the host suppresses the progression of cancer in mouse breast cancer models2024

Author(s)

Organizer

Data Source

[Presentation] SPRED2は食道がん細胞のマクロファージをエクソソームのIL-6/STAT3を介して、M2表現形に変化させる2023

Author(s)

Organizer

Data Source

[Presentation] 腫瘍環境のSpred2欠損は乳がんの増殖と転移を抑制する2023

Author(s)

Organizer

Data Source

[Presentation] HCC細胞のオートファジーにおけるSpred2の機能及びmTORC1活性化との関係2023

Author(s)

Yoshimura Teizo 吉村禎造