Fujimoto Kazuma 藤本一眞

… Alternative Names

FUJIMOTO Kazuma 藤本一眞

KAZUMA Fujimoto 藤本一眞

藤本一真フジモトカズマ

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Researcher Number	50181392
Other IDs
External Links
Affiliation (Current)	2025: 国際医療福祉大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019: 佐賀大学, 医学部, 客員研究員 2017 – 2018: 佐賀大学, 医学部, 教授 2012 – 2014: 佐賀大学, 医学部, 教授 2006 – 2010: 佐賀大学, 医学部, 教授 2003 – 2004: 佐賀大学, 医学部, 教授 … More 1997 – 2000: Saga Med.School, Intern.Med., Prof., 医学部, 教授 1996: Faculty of Med.Associate Prof., 医学部, 助教授 1994 – 1995: 佐賀医科大学, 医学部, 講師 1987 – 1989: 九州大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / General internal medicine(including psychosomatic medicine) / 応用薬理学・医療系薬学 / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Gastroenterology / 内分泌・代謝学
Keywords	Principal Investigator アポトーシス / 中枢神経 / 視床下部 / ischemia-reperfusion / 摂食行動 / 中性脂肪 / 虚血再灌流 / cell death / 細胞死 / hypothalamus … More / central nervous system / 小腸粘膜 / 増殖因子 / 増殖機構 / 小腸 / 迷走神経 / 消化吸収 / 代謝調節 / 食欲 / 消化管機能 / 食事 / 発癌抑制 / 消化管 / 脂質 / 培養細胞 / 大腸粘膜 / 発がんモデル動物 / 大腸発がん / Neuronal Histamine / Feeding Behavior / Paraventricular Nucleus / Ventromedial Hypothalamus / Hypothalamus / Histamine H_1-receptor / ニューロン活動 / α-fluoromethylhistidine / H_1受容体 / 視索前野-前視床下野 / 視床下部背内側核 / 外側視床下野 / ヒスタミンH_1受容体拮抗薬 / αーfluoromethylhistidine / 神経性分泌ヒスタミン / 室傍核 / 視床下部腹内側核 / ヒスタミンH_1受容体 / digestion / absorption / appetite / metabolism / jejunum / ileum / ミトコンドリア / 回腸 / 空腸 / olive oil / corn oil / fish oil / beef oil / satuated fatty acid / carcinoma in situ / azoxymethane / Colon cancer / アベラントクリプト / 発癌因子 / 大腸腺腫 / オリーブ油 / コーン油 / 魚油 / 動物性油 / 飽和脂肪酸 / 粘膜内癌 / アゾキシメタン / 大腸癌 / immunohistochemical stain / long chain fatty acids / lipid absorption / intestinal function / 粘膜肥厚 / 糖尿病 / 絨毛 / 免疫組織染色 / 長鎖脂肪酸 / 脂質吸収 / 小腸機能 / circadian variation / mucosal growth / 日内リズム / 粘膜増殖 / vagal nerve / intestine / ornithine / 粘膜修復 / 十二指腸粘膜 / オルニチン脱炭酸酵素 / 膵臓 / シグナル伝達 / 脂肪摂取 / 消化管粘膜 / 肝臓 / 小腸培養 / グレリン / レプチン / 糖類 / アミン類 / 満腹中枢 / 摂食中枢 / 粘膜 / 生活習慣 / メタボリック症候群 / 生理作用 / 小腸粘膜増殖 … More Except Principal Investigator 視床下部 / phosphatidylcholine / Duodenal ulcer / Gastric ulcer / Phospholipids / Apoptosis / Helicobacter pylori / スナネズミ / 胃癌 / 十二指腸潰瘍 / 胃潰瘍 / ホスファチジルコリン / アポトーシス / ヘリコバクターピロリ / リン脂質 / Zucker obese rat / apolipoprtein A-IV / feeding center / feeding / Lipid meal / 小腸 / 肥満症 / 脂質吸収 / Zucker肥満ラット / アポ蛋白A-IV / 摂食中枢 / 摂食行動 / 脂質摂取 / アミノ酸 / HPLC / Histidine decarboxylase / ヒスチジン / 神経ヒスタミン / 神経性食欲不振症 / 神経細胞壊死 / 記憶障害 / CA1錐体細胞 / 海馬 / 脳虚血 / サル Less

Can long-term oral intake of olive oil inhibit promotion of colon cancer? : in vivo and in vitro trialsPrincipal Investigator
- Principal Investigator
  
  Fujimoto Kazuma
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Saga University
Regulation of metabolism related to the gastrointestinal tract via hypothalamus and autonomic nerves: in vivo and in vitro studiesPrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kazuma
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Saga University
Effect of central nervous system on small intestinal cell growth And apoptosisPrincipal Investigator
- Principal Investigator
  
  KAZUMA Fujimoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga University
Apoptotic pathway in the rat small intestinal mucosa is different between physiological conditions and ischemia-reperfusionPrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kazuma
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga University
Long-term oil ingestion promotes invasive colon cancer by inhibiting in azoxymethane-treated ratsPrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kazuma
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga University
  佐賀医科大学
Relationship between apoptosis and lipid absorption in rat intestinePrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kazuma
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga Medical School
EFFECT OF Helicobacter pylori infection Normalization in phospholipids concentration of the gastric mucosa after eradication of in patients with peptic ulcer.
- Principal Investigator
  
  IWAKIRI Ryuichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga Medical School
The effect of the central nervous system on apoptosis in the rat intestinePrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kazuma
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga Medical School
Feeding supression after a lipid meal in normal and obese rats
- Principal Investigator
  
  IWAKIRI Ryuichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga Medical School
神経性食欲不振症の難治化する脳内ヒスタミン機能亢進とその治療法の開発
- Principal Investigator
  
  TOSHIIE Sakata
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  大分医科大学
Effet of CNS on ODC activity in rat intestinePrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kazuma
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga Medical School
サルの脳虚血による海馬CA1錐体細胞の選択的破壊と記憶障害の解析
- Principal Investigator
  
  西条寿夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Institution
  Toyama Medical and Pharmaceutical University
Modulation of feeding behavior through brain histamine Hl-receptorPrincipal Investigator
- Principal Investigator
  
  KAZUMA Fujimoto
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Faculty of Medicine, Kyushu University

[Book] In : Olives and Olive Oil in Health and Disease Prevention(Azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling and the effects of the olive oil.)(edited by Preedy VR and Watson RR.)2010
- Author(s)
  Fujise T, Iwakiri R, Shiraishi R, Fujimoto K
- Publisher
  Academic Press.Oxford
- Data Source
  KAKENHI-PROJECT-20590728
[Book] Azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling and the effects of the olive oil. In : Olives and Olive Oil in Health and Disease Prevention2010
- Author(s)
  Fujise T, Iwakiri R, Fujimoto K
- Publisher
  Academic press Oxford
- Data Source
  KAKENHI-PROJECT-20590728
[Book] 生理(消化管・膵・腹膜の疾患).杉本恒明, 矢崎義雄, 総編集:内科学(第9版)2007
- Author(s)
  藤本一真
- Total Pages
  5
- Publisher
  朝倉書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Book] 生理 (消化管・膵・腹膜の疾患).杉本恒明, 矢崎義雄, 総編集: 内科学 (第9版)2007
- Author(s)
  藤本一真
- Total Pages
  5
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Risk factors for delayed hemorrhage after colonic endoscopic mucosal resection in patients who did not receive antithrombotic therapy: retrospective analysis of 3844 polyps of 1660 patients2019
- Author(s)
  Tsuruta S, Tominaga N, Ogata S, Tsuruoka N, Sakata Y, Shimoda R, Eguchi Y, Anzai K, Hara M, Fujimoto K
- Journal Title
  
  Digestion
  
  Volume: 100 Issue: 2 Pages: 86-92
- DOI
  10.1159/000494455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09307
[Journal Article] Management of patients on antithrombotic agents undergoing emergency and elective endoscopy: joint Asian Pacific Association of Gastroenterology (APAGE) and Asian Pacific Society for Digestive Endoscopy (APSDE) practice guidelines2018
- Author(s)
  Chan FKL, Goh KL, Reddy N, Fujimoto K, Ho KY, Hokimoto S, Jeong YH, Kitazono T, Lee HS, Mahachai V, Tsoi KKF, Wu MS, Yan BP, Sugano K
- Journal Title
  
  Gut
  
  Volume: 67 Pages: 405-417
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09307
[Journal Article] Cancer-adipose tissue interaction and fluid flow synergistically modulate cell kinetics, HER2 expression, and trastuzumab efficacy in gastric cancer2018
- Author(s)
  Akutagawa T, Aoki S, Yamamoto H,Rikitake M, Iwakiri R, Fujimoto K, Toda S
- Journal Title
  
  Gastric Cancer
  
  Volume: 2１ Pages: 946-955
- NAID
  40021694578
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09307
[Journal Article] High-density collagen patch prevents stricture after endoscopic circumferential submucosal dissection of the esophagus: a porcine model2017
- Author(s)
  Aoki S, Sakata Y, Shimoda R, Takezawa T, Oshikata-Miyazaki A, Kimura H, Yamamoto M, Iwakiri R, Fujimoto K, Toda S
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 85 Issue: 5 Pages: 1076-1085
- DOI
  10.1016/j.gie.2016.10.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460941, KAKENHI-PROJECT-16K09284, KAKENHI-PROJECT-17K09307, KAKENHI-PROJECT-17K09352
[Journal Article] Feeding with olive oil attenuates inflammation in dextran sulfate sodium-induced colitis in rat.2014
- Author(s)
  Takashima T, Sakata Y, Iwakiri R, Shiraishi R, Oda Y, Inoue N, Nakayama A, Toda S, Fujimoto K.
- Journal Title
  
  J. Nutr. Biochem.
  
  Volume: 25 Pages: 186-192
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590889
[Journal Article] 小腸粘膜のアポトーシスはどのように制御されているのか2013
- Author(s)
  大谷顕史、藤本一眞
- Journal Title
  
  分子消化器病
  
  Volume: 10 Pages: 22-26
- Data Source
  KAKENHI-PROJECT-24590889
[Journal Article] Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population2012
- Author(s)
  Sumida Y, Yoneda M, Hyogo H, Itoh Y, Ono M, Fujii H, Eguchi Y, Suzuki Y, Aoki N, Kanemasa K, Fujita K, Chayama K, Saibara T, Kawada N, Fujimoto K, Kohgo Y, Yoshikawa T, Okanoue T
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 12 Pages: 2-9
- NAID
  120005122663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590889
[Journal Article] Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study.2012
- Author(s)
  Eguchi Y, Hyogo H, Ono M, Mizuta T, Ono N, Fujimoto K, Chayama K, Saibara T, JSG-NAFLD.
- Journal Title
  
  J. Gastroenterol.
  
  Volume: 47 Pages: 586-595
- NAID
  10030650741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590889
[Journal Article] The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells.2012
- Author(s)
  Xia J, Matsuhashi S, Hamajima H, Iwane S, Takahashi H, Eguchi Y, Mizuta T, Fujimoto K, Kuroda S, Ozaki I.
- Journal Title
  
  J. Nutr. Biochem.
  
  Volume: 23 Pages: 1668-1775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590889
[Journal Article] 生活習慣と消化器疾患・治療薬2012
- Author(s)
  藤瀬剛弘、藤本一眞
- Journal Title
  
  メディシーナル
  
  Volume: 2 Pages: 6-15
- Data Source
  KAKENHI-PROJECT-24590889
[Journal Article] The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease.2011
- Author(s)
  Eguchi Y, Mizuta T, Sumida Y, Ishibashi E, Kitajima Y, Isoda H, Horie H, Tashiro T, Iwamoto E, Takahashi H, Kwashiorkor T, Soejima S, Kawaguchi Y, Oda Y, Emura S, Iwakiri R, Ozaki I, Euchar T, Ono N, Anza K, Fujimoto K, Koizumi S.
- Journal Title
  
  J Gastroenterol. 46Suppl.1
  
  Pages: 70-78
- NAID
  10029030366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Post-allenge hyperglycemia is a significant risk factor for the development of hepatocellular carcinoma in patients with chronic hepatitis C.2011
- Author(s)
  Takahashi H, Mizuta T, Eguchi Y, Kawaguchi Y, Kuwashiro T, Oeda S, Isoda H, Oza N, Iwane S, Izumi K, Anzai K, Ozaki I, Fujimoto K.
- Journal Title
  
  J Gastroenterol. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow.2010
- Author(s)
  Shiraishi R, Iwakiri R, Fujise T, Kuroki T, Kakimoto T, Takashima T, Sakata Y, Tsunada S, Nakashima Y, Yanagita T, Fujimoto K.
- Journal Title
  
  J.Gastroenterol. 45
  
  Pages: 625-635
- NAID
  10027216628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Metabolic factors are associated with serum alanine aminotransferase levels in patients with chronic hepatitis C.2010
- Author(s)
  Kobayashi Y, Kawaguchi Y, Mizuta T, Kwashiorkor T, Ode S, Ooze N, Takahashi H, Inane S, Euchar Y, Anza K, Ozaki I, Fujimoto K.
- Journal Title
  
  J Gastroenterol. [Epub ahead of print]
- NAID
  10029028740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Regulation of tumor suppressor PDCD4 by novel protein kinase C isoforms.2010
- Author(s)
  Nakashima M, Hamajima H, Xia J, Iwane S, Kawaguchi Y, Eguchi Y, Mizuta T, Fujimoto K, Ozaki I, Matsuhashi S.
- Journal Title
  
  Biochem.Biophys.Acta. 1803
  
  Pages: 1020-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Age-related fat deposition in multifidus muscle could be a marker for nonalcoholic fatty liver disease.2010
- Author(s)
  Kitajima Y, Eguchi Y, Ishibashi E, Nakashita S, Aoki S, Toda S, Mizuta T, Ozaki I, Ono N, Eguchi T, Arai K, Iwakiri R, Fujimoto K.
- Journal Title
  
  J Gastroenterol. 45
  
  Pages: 218-224
- NAID
  10027214665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Increased lipid absorption and transport in the small intestine of Zucker obese rats.2009
- Author(s)
  Anzai K, Fukagawa K, Iwakiri R, Fujimoto K, Akashi K, Tso P.
- Journal Title
  
  J Clin Biochem Nutr 45
  
  Pages: 82-85
- NAID
  130004466565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche.2009
- Author(s)
  Ootani A, Li X, Sangiorgi E, Ho OT, Ueno H, Toda S, Sugihara H, Fujimoto K, Weissman IL, Capecchi MR, Kuo CJ.
- Journal Title
  
  Nature Med 15
  
  Pages: 701-706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Higher arterial stiffness, greater peripheral vascular resistance and lower blood flow in lower-leg arteries are associated with long-term hyperglycaemia in type 2 diabetic patients with normal ankle-brachial index.2009
- Author(s)
  Suzuki E, Yoshimura T, Omura Y, Sakaguchi M, NishioY, Maegawa H, Hisatomi A, Fujimoto K, Takeda J, Kashiwaki A.
- Journal Title
  
  Diabetes Metab Res Rev 25
  
  Pages: 363-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Down regulation of cyclooxygenase-1 is involved in gastric mucosal apoptosis via death signaling in portal hypertensive rats.2009
- Author(s)
  Wu B, Zeng L, Lin Y, Wen Z, Chen G, Iwakiri R, Fujimoto K.
- Journal Title
  
  Cell Res. 19
  
  Pages: 1269-1278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Modulation of the transforming growth factor-beta1-induced Smad phosphorylation by the extracellular matrix receptor beta1-integrin.2009
- Author(s)
  Hamajima H, Ozaki I, Zhang H, Iwane S, Kawaguchi Y, Eguchi Y, Matsuhashi S, Mizuta T, Matsuzaki K, Fujimoto K.
- Journal Title
  
  Int J Oncol. 35
  
  Pages: 1441-1447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Long-term ingestion of reduced glutathione suppressed an accelerating effect of beef tallow diet on colon carcinogenesis in rats.2009
- Author(s)
  Shiraishi R, Fujise T, Kuroki T, Kakimoto T, Miao L, Sakata Y, Tsunada S, Noda T, Iwakiri R, Fujimoto K.
- Journal Title
  
  J Gastroenterol. 44
  
  Pages: 1026-1035
- NAID
  10025581768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Inhibition of matrix metalloproteinase expression by menatetrenone, a vitamin K2 analogue.2009
- Author(s)
  Ide Y, Zhang H, Hamajima H, Kawaguchi Y, Eguchi Y, Mizuta T, Yamamoto K, Fujimoto K, Ozaki I.
- Journal Title
  
  Oncol Rep. 22
  
  Pages: 599-604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Hepatitis C virus infection enhances insulin resistance induced by visceral fat accumulation.2009
- Author(s)
  Eguchi Y, Mizuta T, Ishibashi E, Kitajima Y, Oza N, Nakashita S, Hara M, Iwane S, Takahashi H, Akiyama T, Ario K, Kawaguchi Y, Yasutake T, Iwakiri R, Ozaki I, Hisatomi A, Eguchi T, Ono T, Fujimoto K.
- Journal Title
  
  Liver Int 29
  
  Pages: 213-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Fujimoto Suppression of intestinal mucosal apoptosis by ghrelin in fasted rats2008
- Author(s)
  Park, JM., Kakimoto, T., Kuroki, T., Shiraishi, R., Fujise, T., Iwakiri R., Fujimoto, K
- Journal Title
  
  Exp Biol Med 233
  
  Pages: 48-56
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Fujimoto Indigestible material attenuated changes in apoptosis in the fasted rat jejunal mucosa2008
- Author(s)
  Kakimoto, T., Fujise, T., Shiraishi, R., Kuroki, T., Park, JM., Ootani, A., Sakata, Y., Tsunada, S., Iwakiri, R., Fujimoto K
- Journal Title
  
  Exp Biol Med 233
  
  Pages: 310-316
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Suppression of intestinal mucosal apoptosis by ghrelin in fasted rats.2008
- Author(s)
  Park JM, Kakimoto T, Kuroki T, Shiraishi R, Fujise T, Iwakiri R, Fujimoto K.
- Journal Title
  
  Exp Biol Med 233
  
  Pages: 48-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Indigestible material attenuated changes in apoptosis in the fasted rat jejunal mucosa.2008
- Author(s)
  Kakimoto T, Fujise T, Shiraishi R, Kuroki T, Park JM, Ootani A, Sakata Y, Tsunada S, Iwakiri R, Fujimoto K.
- Journal Title
  
  Exp Biol Med 233
  
  Pages: 310-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Journal Article] Adipocytes and preadipocytes promote the proliferation of colon cancer cells in vitro2007
- Author(s)
  Amemori, S., Ootani, A., Aoki, S., Fujise, T., Shimoda, R., Kakimoto, T., Shiraishi, R., Sakata, Y., Tsunada, S., Iwakiri, R., Fujimoto, K
- Journal Title
  
  Am. J. Physiol 292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Differentiation of Gastric Surface Mucous Cells(GSM06) Induced by Air Liquid Interface Is Regulated' Partly through Mitogen-Activated Protein Kinase Pathway2007
- Author(s)
  Yokoyama, F., Sakata, Y., Ootani, A., Fujise, T., Kakimoto, T., Amemori, S., Kuroki, T., Tsunada, S., Iwakiri, R., Fujimoto, K
- Journal Title
  
  J. Gastroenterol. Hepatol 22
  
  Pages: 2310-2315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Long term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/β-catenin signaling in rats2007
- Author(s)
  Fujise, T., Iwakiri, R., Kakimoto, T., Shiraishi, R., Sakata, Y., Wu, B., Tsunada, S., Ootani, A., Fujimoto, K
- Journal Title
  
  Am J Physiol 292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Apoptotic pathway in the rat small intestinal mucosa is different between fasting and ischemia-reperfusion2006
- Author(s)
  Fujise, T., Iwakiri, R., Wu, B., Amemori, S., Kakimoto, T., Yokoyama, F., Sakata, Y., Tsunada, S., Fujimoto, K
- Journal Title
  
  Am. J. Physio 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590690
[Journal Article] Ischemic preconditioning attenuates ischemia-repermsion-induced mucosal apoptosis by inhibiting the mitochondria-dependent pathway in rat small intestine.2004
- Author(s)
  Wu B, Ootani A, Iwakiri R, Fujise T, Tsunada S, Toda S, Fujimoto K.
- Journal Title
  
  Am.J.Physiol. 286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590658
[Journal Article] Dietary corn oil promotes colon cancer by inhibiting mitochondria-dependent apoptosis in azoxymethane-treated rats.2004
- Author(s)
  Wu B, Iwakiri R, Ootani A, Tsunada S, Fujise T, Sakata Y, Sakata H, Toda S, Fujimoto K.
- Journal Title
  
  Exp.Biol.Med. 229
  
  Pages: 1017-1025
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590658
[Journal Article] Platelet-activating factor promotes mucosal apoptosis via FasL-mediating caspase-9 active pathway in rat small intestine after ischemia-reperfusion.2003
- Author(s)
  Wu B, Iwakiri R, Ootani A, Fujise T, Tsunada S, Fujimoto K.
- Journal Title
  
  FASEB J. 17
  
  Pages: 1156-1158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590658
[Journal Article] Redox imbalance in the colonic mucosa of ulcerative colitis.2003
- Author(s)
  Tsunada S, Iwakiri R, Ootani H, Aw TY, Fujimoto K.
- Journal Title
  
  Scand.J.Gastroenterol 38
  
  Pages: 1002-1003
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590658
[Journal Article] Foveolar differentiation of mouse gastric mucosa invitro.2003
- Author(s)
  Ootani A, Toda S, Fujimoto K, Sugihara H.
- Journal Title
  
  Am.J.Pathol. 162
  
  Pages: 1905-1912
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590658
[Journal Article] Effect of antioxidative agents on apoptosis induced by ischemia-reperfusion in rat intestinal mucosa.2003
- Author(s)
  Kojima M, Iwakiri R, Wu B, Fujise T, Watanabe K, Lin T, Amemori S, Sakata H, Shimoda R, Ogusu T, Ootani A, Tsunada S, Fujimoto K.
- Journal Title
  
  Aliment.Pharmacol.Therap. 18(supple 1)
  
  Pages: 139-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590658
[Journal Article] The interaction between adipose tissue stromal cells and gastric cancer cells : roles of the stromal cells in the progression and HER2-targeted therapy of the cancer.
- Author(s)
  Nomoto N, Aoki S, Uchihashi K, Matsunobu A, Koike E, Ootani A, Yonemitsu N, Fujimoto K, Toda S.
- Journal Title
  
  Cancer Sci in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 研究におけるデータ管理2020
- Author(s)
  藤本一眞
- Organizer
  第16回日本消化管学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09307
[Presentation] Fluid flow stress modulates gastric carcinoma cell kinetics in cancer-adipose tissue interactions2018
- Author(s)
  Akutagawa T, Aoki S, Sakata Y, Fujimoto K, Toda S
- Organizer
  Digestive Disease Week 2018 (AGA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09307
[Presentation] 大腸癌発育進展におけるFusobacterium属の役割とエピゲノム胃常、免疫応答との関連2018
- Author(s)
  樋髙秀憲、東元　健、古賀靖大、岩切龍一、能城浩和、藤本一眞、副島英伸
- Organizer
  第14回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-17K09307
[Presentation] Fluid flow stress amplifies the proliferation of gastric carcinoma cells promoted by adipose tissue2017
- Author(s)
  Akutagawa T, Fujimoto K, Aoki S, Toda S.
- Organizer
  Asian Pacific Digestive Week (APDS)2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09307
[Presentation] 肥満、代謝異常と消化管疾患、病態解明への新たなアプローチ:脂肪組織由来間質細胞はCOX-2非依存性にMARK(pERK-1/2)活性化およびHER2発現抑制を介して、胃癌の進展に関与する2011
- Author(s)
  野本菜実絵、戸田修二、藤本一眞
- Organizer
  第7回日本消化管学会総会学術集会抄録集255(ワークショップ)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 肝疾患での間質実質相互作用、形質転換から見た治療戦略:細胞接着因子β1-インテグリンによる増殖因子のシグナル伝達への関与の解明2010
- Author(s)
  岩根紳治、尾崎岩太、藤本一眞
- Organizer
  第52回日本消化器病学会大会日消誌107(Suppl):A79 (ワークショップ)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] Visceral fat accumulation is the first and second hit pathogenesis for development of nonalcoholic fatty liver disease.2010
- Author(s)
  Eguchi Y, Mizuta T, Kawaguchi Y, Ozaki I, Ono N, Eguchi T, Fujimoto K.
- Organizer
  The Second International Forum of Japanese Society of Gastroenterology.日消誌107:A61(Plenary Oral Presentation)
- Place of Presentation
  Niigata
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 生活習慣病と消化管疾患:生活習慣病と大腸発癌について、ラット発癌モデルでの検討2010
- Author(s)
  冨永直之、白石良介、岩切龍一、藤本一眞
- Organizer
  第6回日本消化管学会総会学術集会抄録集250(ワークショップ)
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 消化器臓器における幹細胞研究の進歩 : In vivo analysis of intestinal stem cells2009
- Author(s)
  大谷顕史、藤本一眞、Kuo K.
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 大腸癌の予防:脂肪長期摂取と大腸発癌ラット発癌モデルでの検討2009
- Author(s)
  白石良介、岩切龍一、藤本一眞
- Organizer
  第95回日本消化器病学会総会日消誌106:A105(ワークショップ)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] Long term treatment of dyspepsia and GERD with PPI.2009
- Author(s)
  藤本一眞
- Organizer
  13^<th> International Conference on Gastrointestinal Research.(Split, Croatia) Abstract 33 (Invited Lecture)
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 消化器臓器における幹細胞研究の進歩:In vivo analysis of intestinal stem cells.2009
- Author(s)
  大谷顕史、藤本一眞、Kuo K.
- Organizer
  第95回日本消化器病学会総会日消誌 106:A68(パネルディカスッション)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] What regulates appetite, glucose or apo A-IV?2009
- Author(s)
  藤本一眞
- Organizer
  Second Karuizawa Seminar.Abstract 5 (Lecture)
- Place of Presentation
  Karuizawa
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 消化吸収機能における小腸粘膜の形態維持と中枢神経との関連について2008
- Author(s)
  藤瀬剛弘、野田隆博、藤本一眞
- Organizer
  第39回日本消化吸収学会総会日消誌 105:A628(パネルディカスッション)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] Recapitulation of the Wnt-dependent intestinal stem cell niche in long-term culture2008
- Author(s)
  大谷顕史、藤本一眞、Calvin Kuo.
- Organizer
  第94回日本消化器病学会総会日消誌 105: A102(パネルディカスッション)
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590728
[Presentation] 生活習慣病と脂質・胆汁酸代謝：脂肪組織はIGF-１を介して食道扁平上皮癌の増殖、浸潤、分化を促進し、アポトーシスを抑制する
- Author(s)
  中山敦史、岩切龍一、藤本一眞
- Organizer
  第56回日本消化器病学会大会　シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-24590889

1. IWAKIRI Ryuichi (70232642)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
2. TODA Syuji (80188755)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. TOSHIIE Sakata (50037420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAKATA Hiroyuki (90253608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 西条寿夫 (00189284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中村清実 (20143860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 福田正治 (60126547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小野武年 (50019577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤靖史 (50178779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 吉松博信 (00166993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂田資尚 (50404158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 鶴岡ななえ (90535759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Fujimoto Kazuma 藤本 一眞

FUJIMOTO Kazuma 藤本 一眞

KAZUMA Fujimoto 藤本 一眞

藤本 一真 フジモト カズマ

Research Projects

Research Products

Co-Researchers

Can long-term oral intake of olive oil inhibit promotion of colon cancer? : in vivo and in vitro trialsPrincipal Investigator

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Regulation of metabolism related to the gastrointestinal tract via hypothalamus and autonomic nerves: in vivo and in vitro studiesPrincipal Investigator

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Effect of central nervous system on small intestinal cell growth And apoptosisPrincipal Investigator

Principal Investigator

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Apoptotic pathway in the rat small intestinal mucosa is different between physiological conditions and ischemia-reperfusionPrincipal Investigator

Principal Investigator

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Long-term oil ingestion promotes invasive colon cancer by inhibiting in azoxymethane-treated ratsPrincipal Investigator

Principal Investigator

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Relationship between apoptosis and lipid absorption in rat intestinePrincipal Investigator

Principal Investigator

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EFFECT OF Helicobacter pylori infection Normalization in phospholipids concentration of the gastric mucosa after eradication of in patients with peptic ulcer.

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The effect of the central nervous system on apoptosis in the rat intestinePrincipal Investigator

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Feeding supression after a lipid meal in normal and obese rats

Principal Investigator

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神経性食欲不振症の難治化する脳内ヒスタミン機能亢進とその治療法の開発

Principal Investigator

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Effet of CNS on ODC activity in rat intestinePrincipal Investigator

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サルの脳虚血による海馬CA1錐体細胞の選択的破壊と記憶障害の解析

Principal Investigator

Project Period (FY)

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Modulation of feeding behavior through brain histamine Hl-receptorPrincipal Investigator

Principal Investigator

Fujimoto Kazuma 藤本一眞

FUJIMOTO Kazuma 藤本一眞

KAZUMA Fujimoto 藤本一眞

藤本一真フジモトカズマ

[Book] 生理(消化管・膵・腹膜の疾患).杉本恒明, 矢崎義雄, 総編集:内科学(第9版)2007