Yanagisawa Ken 柳澤健

… Alternative Names

YANAGISAWA Ken 柳澤健

柳沢健ヤナギサワケン

柳澤健ヤナギサワケン

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Researcher Number	50182366
Other IDs
External Links
Affiliation (Current)	2025: 天使大学, 看護栄養学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2016: 自治医科大学, 医学部, 教授 2009: 自治医科大学, 医学部, 教授 2008: 自治医科大学, 医学部, 准教授 1996 – 1998: 自治医科大学, 医学部, 助教授 1991: 自治医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator General medical chemistry / Cell biology Except Principal Investigator Functional biochemistry / Pathological medical chemistry
Keywords	Principal Investigator CD14 / IL-33 / MD2 / TLR4 / 炎症反応 / 細胞形質転換 / LPS受容体 / 細胞がん化 / シグナル伝達 / LPS … More / ST2 / サイクリン依存性キナーゼインヒビッター / 接触阻害 / サンクリン依存性キナーゼインヒビッター / リポソーム / コンタクトインヒビション … More Except Principal Investigator ST2L / ST2 / 細胞増殖 / promoter / IL-1 receptor family / モノクローナル抗体 / プロモーター / IL-1受容体ファミリー / 免疫学 / 糖鎖 / タンパク質 / シグナル伝達 / アレルギー・ぜんそく / 抗炎症作用 / 糖鎖修飾 / ST2遺伝子 / 細胞間相互作用 / 分泌タンパク質 / G_1移行期 / G_0 / 細胞周期 / インタ-ロイキン1受容体 / イミュノグロブリンス-パ-ファミリ- Less

Investigation on inhibitory mechanism of soluble ST2 protein (secreted IL-33 receptor) against LPS signalPrincipal Investigator
- Principal Investigator
  
  Yanagisawa Ken
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Jichi Medical University
Identification of functional regions the soluble ST2 protein against inflammation, and its possible application for novel drugs.
- Principal Investigator
  
  TOMINAGA Shinichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Jichi Medical University
Functional analysis of the Interleukin-1 Receptor-Related ST2 Gene Products
- Principal Investigator
  
  IWAHANA Hiroyuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Jichi Medical School
コンタクトインヒビションに関与する細胞表面タンパク質の精製とクローニングPrincipal Investigator
- Principal Investigator
  
  柳沢健
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Jichi Medical University
細胞増殖開始過程で特異的に発現されるST2遺伝子産物の生物学的機能
- Principal Investigator
  
  TOMINAGA Shinichi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University

All 2017 2016 2015 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] STAT3 and ERK pathways are involved in cell growth stimulation of the ST2/IL1RL1 promoter2017
- Author(s)
  Tago K, Ohta S, Funakoshi-Tago M, Aoki-Ohmura C, Matsugi J, Tominaga SI, Yanagisawa K
- Journal Title
  
  FEBS Open Bio
  
  Volume: 7(2) Issue: 2 Pages: 293-302
- DOI
  10.1002/2211-5463.12192
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-26460376, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17K08286
[Journal Article] Intracellular NF-HEV/IL-33 harbors essential roles in Ras-induced cellular transformation by contributing to cyclin D1 protein synthesis.2016
- Author(s)
  S. Ohta, K. Tago, M. Funakoshi-Tago, J. Matsugi, K. Yanagisawa
- Journal Title
  
  Cellular Signalling
  
  Volume: 0 Issue: 8 Pages: 0-0
- DOI
  10.1016/j.cellsig.2016.04.013
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460376, KAKENHI-PROJECT-26440062
[Journal Article] ST2 gene expression is proliferation-dependent and its ligand, IL-33, induces inflammatory reaction in endothelial cells2010
- Author(s)
  Aoki, S., Hayakawa, M., Ozaki, H., Takezako, N., Obata, H., Ibaraki, N., Tsuru, T., Tominaga, S., Yanagisawa, K.
- Journal Title
  
  Mol. Cell. Biochem. 335
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] IL-33前駆体は、がん化型Ras変異体が誘導する形質転換とサイクリンD1タンパク質合成に必須の役割を担う2015
- Author(s)
  太田　聡、多胡　憲治、多胡　めぐみ、松儀　実広、柳澤　健
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460376
[Presentation] 新規IL-33シグナル調節蛋白質IFITM3の同定2015
- Author(s)
  多胡　憲治、多胡　めぐみ、太田　聡、松儀　実広、柳澤　健
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26460376
[Presentation] IL-33 induces inflammatory reaction in endothelial cells, and its receptor, ST2L is expressed in growth-dependent manner. (IL-33は内皮細胞に炎症反応を惹起し, その受容体のST2Lは増殖依存性に内皮細胞に発現する. )2009
- Author(s)
  柳澤健, 太田聡, 松儀実広, 富永眞一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] IL-33は内皮細胞に炎症反応を惹起し、その受容体のST2Lは増殖依存性に内皮細胞に発現する2009
- Author(s)
  柳澤健, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] ST2遺伝子と病気2008
- Author(s)
  富永眞一, 早川裕子, 早川盛禎, 柳澤健
- Organizer
  3学会合同大会2008自然免疫の最前線第73回日本インターフェロン・サイトカイン学会学術集会/第19回日本生体防御学会学術集会/第45回補体シンポジウム3学会合同集会
- Place of Presentation
  札幌
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] Incadronate can induce apoptosis in monocytic cells2007
- Author(s)
  Miwa, A., Takezako, N., Hayakawa, M., Yanagisawa, K., Tominaga, S.
- Organizer
  XIth International Myeloma Workshop and the IVth International Workshop on Waldenstrom's Macroglobulinemia
- Place of Presentation
  Kos Island, Greece
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] 分泌型ST2タンパク質による単球系細胞の樹状細胞への分化抑制作用について2007
- Author(s)
  竹迫直樹, 早川裕子, 早川盛禎, 松儀実広, 柳澤健, 村尾捷利, 富永眞一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590318

1. TOMINAGA Shinichi (70155571)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. OHTA Satoshi (40528428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. TAKEZAKO Naoki (80424026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. IWAHANA Hiroyuki (80291623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 多胡憲治 (20306111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 小坂明子 (10281297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yanagisawa Ken 柳澤 健

YANAGISAWA Ken 柳澤 健

柳沢 健 ヤナギサワ ケン

柳澤 健 ヤナギサワ ケン

Research Projects

Research Products

Co-Researchers

Investigation on inhibitory mechanism of soluble ST2 protein (secreted IL-33 receptor) against LPS signalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of functional regions the soluble ST2 protein against inflammation, and its possible application for novel drugs.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of the Interleukin-1 Receptor-Related ST2 Gene Products

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

コンタクトインヒビションに関与する細胞表面タンパク質の精製とクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞増殖開始過程で特異的に発現されるST2遺伝子産物の生物学的機能

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] STAT3 and ERK pathways are involved in cell growth stimulation of the ST2/IL1RL1 promoter2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intracellular NF-HEV/IL-33 harbors essential roles in Ras-induced cellular transformation by contributing to cyclin D1 protein synthesis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ST2 gene expression is proliferation-dependent and its ligand, IL-33, induces inflammatory reaction in endothelial cells2010

Author(s)

Journal Title

Data Source

[Presentation] IL-33前駆体は、がん化型Ras変異体が誘導する形質転換とサイクリンD1タンパク質合成に必須の役割を担う2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 新規IL-33シグナル調節蛋白質IFITM3の同定2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IL-33 induces inflammatory reaction in endothelial cells, and its receptor, ST2L is expressed in growth-dependent manner. (IL-33は内皮細胞に炎症反応を惹起し, その受容体のST2Lは増殖依存性に内皮細胞に発現する. )2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IL-33は内皮細胞に炎症反応を惹起し、その受容体のST2Lは増殖依存性に内皮細胞に発現する2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ST2遺伝子と病気2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Yanagisawa Ken 柳澤健

YANAGISAWA Ken 柳澤健

柳沢健ヤナギサワケン

柳澤健ヤナギサワケン