Toki Tsutomu 土岐力

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TOKI Tsutomu 土岐力

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Researcher Number	50195731
Other IDs
External Links
Affiliation (Current)	2025: 弘前大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2016 – 2024: 弘前大学, 医学研究科, 講師 2016: 弘前大学, 大学院医学研究科, 講師 2011 – 2015: 弘前大学, 医学(系)研究科(研究院), 講師 2013: 弘前大学, 大学院医学研究科, 講師 2007 – 2011: Hirosaki University, Graduate School of Medicine, Lecturer 2003 – 2006: 弘前大学, 医学部, 講師 1994 – 2002: 弘前大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Biological Sciences / Medium-sized Section 52:General internal medicine and related fields / Neurology
Keywords	Principal Investigator NF-E2 / 転写因子 / BACH1 / GATA1 / ダウン症 / 白血病 / 赤血球造血 / Transcription factor / 巨核球 / Megakaryocyte … More / BACH2 / ダウン症候群 / 一過性骨髄増殖症 / Bach1 / スプライシング / 急性巨核芽球性白血病 / RUNX1 / 小児白血病 / リボゾーム・タンパク / リボソームタンパク質 / TP53 / ダイアモンド・ブラックファン貧血 / Down's syndrome / Erythropoiesis / Thrombopoiesis / 血小板造血 / 一過性骨髄異常増殖症 / 乳児急性骨髄性白血病 / BACHI / GATA-1 / 急性巨核球性白血病 / c-KIT / bach2 / bach1 / 赤芽球系転写因子 / mafG / mafK / small maf / 組織特異的転写因子 … More Except Principal Investigator ダウン症候群 / GATA1 / 転写因子 / 白血病 / Bach2 / TAM / TMD / Bach1 / 急性巨核球性白血病 / 急性巨核芽球性白血病 / ダウン症 / KIT / 巨核球 / コヒーシン / CRLF2 / JAK2 / 急性リンパ性白血病 / 分子標的療法 / RUNX1 / JAK3 / 21番染色体 / cncファミリー / NF-E2 / 急性骨髄性白血病 / MYC / p53 / MDM2 / Diamond-Blackfan貧血 / 一過性異常骨髄増殖症 / Down syndrome / transcription factor / B cell / B細胞 / GATA-1 / mafG / mafK / Nrf2 / NF-E2転写因子 / GATA転写因子 / 遺伝子改変 / 免疫細胞療法 / 抗体依存性細胞傷害 / 細胞療法 / 遺伝子治療 / 小児がん / 免疫療法 / 分子標的治療 / シグナル伝達 / 小児血液学 / BACH1 / 赤血球造血 / Nrf1 / 造血幹細胞 / 赤血球 / 新規治療法 / 一過性骨髄異常増殖症 / CDKN2A / 骨髄性白血病 / 骨髄病変 / BRAFV600E / BRAFV600E変異 / 測定可能残存病変 / 微小残存病変 / BRAF遺伝子 / ランゲルハンス細胞組織球症 / 組織球症 / 血小板数 / 血小板 / 赤血球分化 / ダウン症関連急性巨核芽球性白血病 / 腫瘍抑制因子 / 血球分化 / ダウン症候群に伴う骨髄性白血病 / IRX1 / 造血不全モデルマウス / 難病プラットフォーム / リボソーム / 悪性腫瘍 / 急性巨核芽性白血病 / 付加的遺伝子異常 / MYC/E2F経路 / リボゾーム蛋白遺伝子 / RNA-seq / マウス胎仔線維芽細胞 / 造血不全 / リボゾームタンパク / リボゾーム / リボゾーム蛋白 / 遺伝子変異 / 肝障害 / 好酸球増多症 / 巨核球系分化 / 巨核球造血 / トランスレーショナルリサーチ / 移植・再生医療 / 免疫学 / 癌 / キメラ受容体 / キメラ型受容体 / MRD / 小児白血病 / Down症候群 / leukemia / transgenic mouse / transcriptional factor / Acute megakaryocytic leukemia / トランスジェニックマウス / cnc family / oncファミリー / Transcription factor / Bach 2 / Bリンパ球 / Nrf3 / NF-E2 transcription factors / GATA transcription factors / CATA転写因子 / Nfr1 / p45 NF-E2 / megakaryocyte / p45NF-E2 / NF-E2 transcription factor / GATA-1 transcription factor / Aplastic anemia / 再生不良性貧血 / MAF FAMILY / NF-E2 TRANSCRIPTION FACTOR / MEGAKARYOCYTES / 組織特異的転写因子 / mafファミリー / 抗体依存性細胞性障害 / T細胞 / 遺伝子改変T細胞療法 / 抗体医療 / 抗体療法 / 抗体依存性細胞障害 / FLT3 / エピゲノム / JAK / RAS / レセプターチロシンキナーゼ / EZH2 / CTCF / BTG1 / IKZF1 / EBF1 / 巨核球性白血病 / 21判染色体 / 自然寛解 / 先天性白血病 / 一過性骨髄増殖性疾患 / 一渦性骨髄増殖性疾患 / 発現量 / GATA1s / 発現クローニング / 一過性白血病 / AMKL / AML1 / STAT3 / WL-DS / 薬剤感受性 / ALL / STI571 / 酸化ストレス / 化学療法 / 薬剤耐性 / Ph1陽性ALL / 血小板造血 / 小脳皮質 / メンケス病モデルマウス / 免疫組織化学 / Ca^<2+>結合蛋白質 / MafG / MafK Less

Understanding of the molecular mechanisms of myeloid leukemia associated with Down syndrome and developing molecular target therapy
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
ダウン症候群の一過性骨髄異常増殖症における新規治療法の開発を目指した基礎的検討
- Principal Investigator
  
  照井君典
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
ダウン症関連白血病における転写因子GATA1スプライシング異常の影響と作用機構Principal Investigator
- Principal Investigator
  
  土岐力
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Diamond-Blackfan貧血に合併する悪性腫瘍発症機構の解明
- Principal Investigator
  
  神尾卓哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jikei University School of Medicine
  Hirosaki University
Elucidation of the function of transcription factor, IRX1, in erythropoesis
- Principal Investigator
  
  Sato Tomohiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Effects of GATA1 mutation types on megakaryocytic differentiation and development of leukemia
- Principal Investigator
  
  Terui Kiminori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Molecular Mechanisms of Bone Marrow Disease in Langerhans cell histiocytosis (LCH)
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Clarification of the mechanism of multistep leukemogenesis of acute megakaryoblastic leukemia associated with Down syndrome and development of the molecular targeted therapy
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Functional analysis of the tandem duplication mutation RUNX1 in leukemogenesisPrincipal Investigator
- Principal Investigator
  
  Toki Tsutomu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Functional analysis of a transcription factor, IRX1, in megakaryocyte differentiation
- Principal Investigator
  
  Sato Tomohiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Effects of GATA1 mutation types on eosinophilia and liver dysfunction
- Principal Investigator
  
  Terui Kiminori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Elucidation of etiology in Diamond-Blackfan anemia focusing on the ribosomal protein genes abnormality
- Principal Investigator
  
  KAMIO TAKUYA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Multistep molecular mechanisms for acute megakaryoblastic leukemia in Down syndrome
- Principal Investigator
  
  Ito Etsuro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hirosaki University
Elucidation of the pathogenesis of diamond-blackfan anemia and identification of novel therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  Toki Tsutomu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Cancer immnotherapy to augment antibody dependent cellular cytotoxicity
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Development of an epoch-making method for identification of Down syndrome patients with TAM who will subsequently develop acute megakaryoblastic leukemia
- Principal Investigator
  
  Ito Etsuro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
The multistep molecular mechanism of acute megakaryoblastic leukemia in Down syndrome
- Principal Investigator
  
  Ito Etsuro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Molecular mechanisms of development of Down syndrome-associated acute lymphoblastic leukemia and novel therapeutic targets for this disease
- Principal Investigator
  
  Terui Kiminori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
a novel adoptive T cell therapy exerting ADCC for pediatric cancer
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Elucidation of molecular mechanism of leukemogenesis with GATA1 and cohesin gene mutations
- Principal Investigator
  
  KANEZAKI RIKA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Investigation of cis-elements recognized by mutatnt GATA1 by chromation immunoprecipitation sequencing analysisPrincipal Investigator
- Principal Investigator
  
  TOKI Tsutomu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
The study on the mechanisms of leukemogenesis caused by qualitative and quantitative abnormalities of GATA1 transcription factor
- Principal Investigator
  
  ITO ETSURO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Molecular mechanisms of abnormal cell proliferation in acute lymphoblastic leukemia of Down syndrome
- Principal Investigator
  
  TERUI KIMINORI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Isolation of novel class I mutation in infantile acute myeloidPrincipal Investigator
- Principal Investigator
  
  TOKI Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
The molecular mechanisms of transient leukemia by GATA1 mutation and development of molecular target therapy
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Molecular mechanisms of abnormal cell proliferation in transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome
- Principal Investigator
  
  TERUI Kiminori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Functional characterization of transcription factor BACH-1 and GATA-1 in phenotype of acute megakaryocytic leukemiaPrincipal Investigator
- Principal Investigator
  
  TOKI Tsutomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Molecular mechanisms of multi-step leukemogenesis in Down syndrome
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
The molecular mechanisms of leukmogenesis by GATA1
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
The differential regulation of target genes by transcription factor BACH 1 in erythroid and megakaryocytic cells.Principal Investigator
- Principal Investigator
  
  TOKI Tsutomu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
ダウン症候群に伴う急性巨核球性白血病の転写因子による発症機構
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
BACH1転写因子活性化を利用した小児白血病の治療法の開発
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
BACH2転写因子活性化を利用したフィラデルフィア染色体陽性白血病の治療法の開発
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Functional analysis of transcription factor BACH1 on thrombopiesis and megakaryocyte diffrentiationPrincipal Investigator
- Principal Investigator
  
  TOKI Tsutomu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Identification of the causative genes fox Down syndrome associated acute megakaryocytic leukemia
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Bach転写因子群による発がんの分子機構
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Study of the function and target genes of BACH transcripton factors.Principal Investigator
- Principal Investigator
  
  TOKI Tsutomu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Bach転写因子群による発がんの分子機構
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
メンケス病マウスの遺伝子治療
- Principal Investigator
  
  吉村教あき
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Study for the mechanism of lymphocyte development by Bach2 transcription factor and clinical analysis of Bach2 gene
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Bach転写因子群による発がんの分子機構
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hirosaki University
トランスジェニック・マウスを用いた転写因子ヒトBach1の機能解析Principal Investigator
- Principal Investigator
  
  土岐力
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Study for the mechanism of lymphocyte development by NF-E2 transcription factors and clinical analysis of NF-E2 gene.
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  HIROSAKI UNIVERSITY
NF-E2関連蛋白による赤血球造血の分子機構
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Asahikawa Medical College
ヒトBach転写因子cDNAのクローニングPrincipal Investigator
- Principal Investigator
  
  土岐力
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Analysis of expression of transcription factors during erythroid development of hematpoietic stem.
- Principal Investigator
  
  YOKOYAMA Masaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  HIROSAKI UNIVERSITY
ヒトsmall maf遺伝子のクローニングPrincipal Investigator
- Principal Investigator
  
  土岐力
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
Megakaryocytic differentiation of hematopoietic stem cell by NF-E2 transcription factors.
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosake University
Analysis of expression of lineage-specific transcription factors during stem cell differentiation in aplastic anemia.
- Principal Investigator
  
  YOKOYAMA Masaru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
巨核球分化にともなう転写因子NF-E2のダウンレギュレーションのしくみPrincipal Investigator
- Principal Investigator
  
  土岐力
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
New classification of infantile leukemia using lineage-specific transcription
- Principal Investigator
  
  ITO Etsuro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  HIROSAKI UNIVERSITY

[Book] 遺伝性骨髄不全症診療ガイドライン20232023
- Author(s)
  伊藤悦朗、土岐力、照井君典、その他
- Total Pages
  91
- Publisher
  診断と治療社
- ISBN
  9784787825599
- Data Source
  KAKENHI-PROJECT-23K21429
[Book] Hematologica disorders in children2017
- Author(s)
  Ito E. Terui K, Toki T et al.
- Total Pages
  269
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26253061
[Book] ダウン症に合併した一過性骨髄異常増殖症におけるGATA1変異と急性白血病への進展. Annual Review血液2012.高久史麿ら編2012
- Author(s)
  土岐力,伊藤悦朗
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591527
[Book] 造血器腫瘍:Down 症候群に伴う急性巨核球性白血病の分子機構.2007
- Author(s)
  伊藤悦朗, 土岐力
- Publisher
  日本臨床社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Book] 新小児がんの診断と治療:白血病 iv)その他白血病類縁疾患.2007
- Author(s)
  伊藤悦朗, 土岐力
- Publisher
  診断と治療社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome2024
- Author(s)
  Tanaka Tatsuhiko、Kudo Ko、Kanezaki Rika、Yuzawa Kentaro、Toki Tsutomu、Okuse Ryo、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Experimental Hematology
  
  Volume: 132 Pages: 104179-104179
- DOI
  10.1016/j.exphem.2024.104179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms2024
- Author(s)
  Sato Tomohiko、Yoshida Kenichi、...、Matsuo Hidemasa、...、Ito Etsuro
- Journal Title
  
  Blood
  
  Volume: - Issue: 25 Pages: 2627-2643
- DOI
  10.1182/blood.2023022247
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-22K08508, KAKENHI-PROJECT-23K07847, KAKENHI-PROJECT-21K07766, KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-22K16320
[Journal Article] Transient erythroblastopenia due to a GATA1 variant in an infant female2023
- Author(s)
  Yamashita Motoi、Tomoda Takahiro、Mizuo Ami、Isoda Takeshi、Egawa Makiko、Yoshida Masayuki、Toki Tsutomu、Kudo Ko、Terui Kiminori、Ito Etsuro、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 71 Issue: 3
- DOI
  10.1002/pbc.30834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond‐Blackfan anaemia2022
- Author(s)
  Kobayashi Akie、Ohtaka Ryusei、Toki Tsutomu、Hara Junichi、Muramatsu Hideki、Kanezaki Rika、Takahashi Yuka、Sato Tomohiko、Kamio Takuya、Kudo Ko、Sasaki Shinya、Yoshida Taro、Utsugisawa Taiju、Kanno Hitoshi、Yoshida Kenichi、Nannya Yasuhito、Takahashi Yoshiyuki、Kojima Seiji、Miyano Satoru、Terui Kiminori、et al.
- Journal Title
  
  eJHaem
  
  Volume: 3 Issue: 1 Pages: 163-167
- DOI
  10.1002/jha2.374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly2022
- Author(s)
  Matsumori Haruka、Watanabe Kenji、Tachiwana Hiroaki、Fujita Tomoko、Ito Yuma、Tokunaga Makio、Sakata-Sogawa Kumiko、Osakada Hiroko、Haraguchi Tokuko、Awazu Akinori、Ochiai Hiroshi、Sakata Yuka、Ochiai Koji、Toki Tsutomu、Ito Etsuro、Goldberg Ilya G、Tokunaga Kazuaki、Nakao Mitsuyoshi、Saitoh Noriko
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 7 Pages: 1-18
- DOI
  10.26508/lsa.202101045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06612, KAKENHI-PROJECT-20K15755, KAKENHI-PLANNED-18H05528, KAKENHI-PUBLICLY-21H05753, KAKENHI-PROJECT-19H03192, KAKENHI-PROJECT-20H03223, KAKENHI-PROJECT-20H03520, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-20K07578, KAKENHI-PROJECT-21K06124, KAKENHI-PROJECT-21K18234, KAKENHI-PROJECT-20KK0185, KAKENHI-PLANNED-18H05531, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-23K23845
[Journal Article] Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report2022
- Author(s)
  Kudo Ko、Kubota Yasuo、Toki Tsutomu、Kanezaki Rika、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Sasaki Shinya、Shiba Norio、Tomizawa Daisuke、Adachi Souichi、Yoshida Kenichi、Ogawa Seishi、Seki Masafumi、Takita Junko、Ito Etsuro、Terui Kiminori
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 10 Pages: 3162-3166
- DOI
  10.1182/bloodadvances.2021006383
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-23K21429
[Journal Article] Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders2022
- Author(s)
  Kanezaki Rika、Toki Tsutomu、Terui Kiminori、Sato Tomohiko、Kobayashi Akie、Kudo Ko、Kamio Takuya、Sasaki Shinya、Kawaguchi Koji、Watanabe Kenichiro、Ito Etsuro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20587-20587
- DOI
  10.1038/s41598-022-25046-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.2022
- Author(s)
  Ko Kudo, Tsutomu Toki, Rika Kanezaki, and Etsuro Ito
- Journal Title
  
  Haematologica
  
  Volume: epub ahead Issue: 7 Pages: 000-000
- DOI
  10.3324/haematol.2021.279857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K06938, KAKENHI-PROJECT-20K07442, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-23K24297
[Journal Article] Predictive factors for the development of leukemia in patients with transient abnormal myelopoiesis and Down syndrome2021
- Author(s)
  Yamato G, Deguchi T, Terui K, Toki T, Watanabe T, Imaizumi T, Hama A, Iwamoto S, Hasegawa D, Ueda T, Yokosuka T, Tanaka S, Yanagisawa R, Koh K, Saito AM, Horibe K, Hayashi Y, Adachi S, Mizutani S, Taga T, Ito E, Watanabe K, Muramatsu H.
- Journal Title
  
  Leukemia.
  
  Volume: 35 Issue: 5 Pages: 1480-1484
- DOI
  10.1038/s41375-021-01171-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08744, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-21K07771, KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-20K17414, KAKENHI-PROJECT-23K21429
[Journal Article] Post-induction MRD by FCM and GATA1-PCR are significant prognostic factors for myeloid leukemia of Down syndrome2021
- Author(s)
  Taga Takashi, Terui Kiminori、Toki Tsutomu、Ito Etsuro、et al.
- Journal Title
  
  Leukemia
  
  Volume: - Issue: 9 Pages: 2508-2516
- DOI
  10.1038/s41375-021-01157-w
- NAID
  120006988564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] A Case of Congenital Leukemia With MYB-GATA1 Fusion Gene in a Female Patient2021
- Author(s)
  Ozono Shuichi、Yano Shoichiro、Oishi Saori、Mitsuo Miho、Nakagawa Shinichiro、Toki Tsutomu、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 44 Issue: 1 Pages: e250-e252
- DOI
  10.1097/mph.0000000000002119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia2021
- Author(s)
  Kudo Ko、Sato Tomohiko、Takahashi Yuka、Yuzawa Kentaro、Kobayashi Akie、Kamio Takuya、Sasaki Shinya、Shimada Jun、Otani Katsuki、Tusjimoto Shinichi、Kato Motohiro、Toki Tsutomu、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 43 Issue: 8 Pages: e1173-e1176
- DOI
  10.1097/mph.0000000000002085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-23K21429
[Journal Article] Enzymatic Changes in Red Blood Cells of Diamond-Blackfan Anemia2021
- Author(s)
  Utsugisawa T, Uchiyama T, Toki T, Shimojima-Yamamoto K, Ohga S, Ito E, Kanno H
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 255 Issue: 1 Pages: 49-55
- DOI
  10.1620/tjem.255.49
- NAID
  130008088766
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21429
[Journal Article] New insights into inherited bone marrow failure syndrome2021
- Author(s)
  Ito E, Toki T, Kamio T, Terui K
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 62 Issue: 10 Pages: 1455-1464
- DOI
  10.11406/rinketsu.62.1455
- NAID
  130008113168
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21429
[Journal Article] Down syndrome-related transient abnormal myelopoiesis is attributed to a specific erythro-megakaryocytic subpopulation with GATA1 mutation.2021
- Author(s)
  Nishinaka-Arai Y, Niwa A, Matsuo S, Kazuki Y, Yakura Y, Hiroma T, Toki T, Sakuma T, Yamamoto T, Ito E, Oshimura M, Nakahata T, Saito MK.
- Journal Title
  
  Haematologica
  
  Volume: 106(2) Issue: 2 Pages: 635-640
- DOI
  10.3324/haematol.2019.242693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17358, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-19K16111
[Journal Article] Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in <i>RPS19</i>2021
- Author(s)
  Takafuji Satoru、Mori Takeshi、Nishimura Noriyuki、Yamamoto Nobuyuki、Uemura Suguru、Nozu Kandai、Terui Kiminori、Toki Tsutomu、Ito Etsuro、Muramatsu Hideki、Takahashi Yoshiyuki、Matsuo Masafumi、Yamamura Tomohiko、Iijima Kazumoto
- Journal Title
  
  Pediatric Hematology and Oncology
  
  Volume: 38 Issue: 6 Pages: 515-527
- DOI
  10.1080/08880018.2021.1887984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-23K21429
[Journal Article] Outcome of colorectal cancer in Diamond-Blackfan syndrome with a ribosomal protein S19 mutation2020
- Author(s)
  Kimura Kazuya、Shimazu Kazuhiro、Toki Tsutomu、Misawa Momoko、Fukuda Koji、Yoshida Taichi、Taguchi Daiki、Fukuda Sho、Iijima Katunori、Takahashi Naoto、Ito Etsuro、Nanjyo Hiroshi、Shibata Hiroyuki
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 13 Issue: 6 Pages: 1173-1177
- DOI
  10.1007/s12328-020-01176-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039
[Journal Article] Clinical, cytogenetic, and molecular analyses of 17 neonates with transient abnormal myelopoiesis and nonconstitutional trisomy 212020
- Author(s)
  Yuzawa Kentaro、Terui Kiminori、Toki Tsutomu、Kanezaki Rika、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Kudo Ko、Sasaki Shinya、Endo Mikiya、Ozono Shuichi、Nomura Keiko、Ito Etsuro
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 67 Issue: 4
- DOI
  10.1002/pbc.28188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07782, KAKENHI-PROJECT-18K07810
[Journal Article] Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond?Blackfan anemia2020
- Author(s)
  Koyamaishi Shun、Ogawa Seishi et al.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 56 Issue: 5 Pages: 1013-1020
- DOI
  10.1038/s41409-020-01056-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07868, KAKENHI-PROJECT-23K21429
[Journal Article] Comprehensive genetic analyses of relapsed B-cell precursor acute lymphoblastic leukemia in children2019
- Author(s)
  Kaori Kubo, Ko Kudo, Tsutomu Toki, Rika Kanezaki, Fumika Ikeda, Tatsuya Ito, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Shinya Sasaki, Kiminori Terui, Etsuro Ito
- Journal Title
  
  Hirosaki Medical Journal
  
  Volume: 70 Pages: 13-13
- NAID
  130007757470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10095
[Journal Article] Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome2019
- Author(s)
  Kubota Yasuo、Ogawa Seishi., et al.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 10 Pages: 3358-3367
- DOI
  10.1111/cas.14160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-18K19467
[Journal Article] Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.2019
- Author(s)
  Watanabe A, Inukai T, Kagami K, Abe M, Takagi M, Fukushima T, Fukushima H, Nanmoku T, Terui K, Ito T, Toki T, Ito E, Fujimura J, Goto H, Endo M, Look T, Kamps M, Minegishi M, Takita J, Inaba T, Takahashi H, Ohara A, Harama D, Shinohara T, Somazu S, Oshiro H, Akahane K, Goi K, Sugita K.
- Journal Title
  
  Cancer Med.
  
  Volume: 7 Issue: 11 Pages: 5274-5288
- DOI
  10.1002/cam4.2356
- NAID
  120007159553
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
[Journal Article] Highly sensitive detection of GATA1 mutations in patients with myeloid leukemia associated with Down syndrome by combining Sanger and targeted next generation sequencing.2019
- Author(s)
  Terui K, Toki T, Taga T, Iwamoto S, Miyamura T, Hasegawa D, Moritake H, Hama A, Nakashima K, Kanezaki R, Kudo K, Saito AM, Horibe K, Adachi S, Tomizawa D, Ito E.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: - Issue: 3 Pages: 160-167
- DOI
  10.1002/gcc.22816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04110
[Journal Article] De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome2018
- Author(s)
  Toki Tsutomu、Yoshida Kenichi、Wang RuNan、Okuno Yusuke、Kataoka Keisuke、Shiraishi Yuichi、Ohga Shouichi、Kuramitsu Madoka、Hamaguchi Isao、Ohara Akira、Kanno Hitoshi、Miyano Satoru、Kojima Seiji、Ishiguro Akira、Sugita Kanji、Kenmochi Naoya、Takahashi Satoru、Eto Koji、Ogawa Seishi、Ito Etsuro
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 103 Issue: 3 Pages: 440-447
- DOI
  10.1016/j.ajhg.2018.07.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10041, KAKENHI-PROJECT-17K10093, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07868, KAKENHI-PROJECT-18H04164
[Journal Article] Two siblings with familial neuroblastoma with distinct clinical phenotypes harboring an ALK germline mutation.2018
- Author(s)
  Kudo K, Ueno H, Sato T, Kubo K, Kanezaki R, Kobayashi A, Kamio T, Sasaki S, Terui K, Kurose A, Yoshida K, Shiozawa Y, Toki T, Ogawa S, Ito E.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: 57 Issue: 12 Pages: 665-669
- DOI
  10.1002/gcc.22676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039
[Journal Article] Atypical erythroblastosis in a patient with Diamond-Blackfan anemia who developed del(20q) myelodysplasia.2018
- Author(s)
  Sonoda M, Ishimura M, Ichimiya Y, Terashi E, Eguchi K, Sakai Y, Takada H, Hama A, Kanno H, Toki T, Ito E, Ohga S.
- Journal Title
  
  Int J Hematol.
  
  Volume: 印刷中 Issue: 2 Pages: 228-231
- DOI
  10.1007/s12185-018-2424-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-16K10041
[Journal Article] Effective response to azacitidine in a child with a second relapse of myeloid leukemia associated with Down syndrome after bone marrow transplantation.2018
- Author(s)
  Uemura S, Mori T, Nagano C, Takafuji S, Nishimura N, Toki T, Terui K, Ito E, Iijima K
- Journal Title
  
  Pediatr Blood Cancer.
  
  Volume: 0 Issue: 12
- DOI
  10.1002/pbc.27414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039
[Journal Article] Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.2017
- Author(s)
  Ikeda F, Yoshida K, Toki T, Uechi T, Ishida S, Nakajima Y, Sasahara Y, Okuno Y, Kanezaki R, Terui K, Kamio T, Kobayashi A, Fujita T, Sato-Otsubo A, Shiraishi Y, Tanaka H, Chiba K, Muramatsu H, Kanno H, Ohga S, Ohara A, Kojima S, Kenmochi N, Miyano S, Ogawa S, Ito E.
- Journal Title
  
  Haematologica.
  
  Volume: - Issue: 3 Pages: e93-e96
- DOI
  10.3324/haematol.2016.153932
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-25291003, KAKENHI-PROJECT-15K09656, KAKENHI-PROJECT-15K15367, KAKENHI-PROJECT-16K10041, KAKENHI-PROJECT-15K09647
[Journal Article] Purification of leukemic blast cells from blood smears using laser microdissection.2017
- Author(s)
  Matsuo H, Shiga S, Imai T, Kamikubo Y, Toki T, Terui K, Ito E, Adachi S.
- Journal Title
  
  Int J Hematol.
  
  Volume: 印刷中 Issue: 1 Pages: 55-59
- DOI
  10.1007/s12185-017-2227-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15K15384, KAKENHI-PROJECT-16K19193
[Journal Article] Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing2017
- Author(s)
  Ichimura T, Yoshida K, Okuno Y, Yujiri T, Nagai K, Nishi M, Shiraishi Y, Ueno H, Toki T, Chiba K, Tanaka H, Muramatsu H, Hara T, Kanno H, Kojima S, Miyano S, Ito E, Ogawa S, Ohga S.
- Journal Title
  
  Int J Hematol.
  
  Volume: 105 Issue: 4 Pages: 515-520
- DOI
  10.1007/s12185-016-2151-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-26461421, KAKENHI-PROJECT-16K10041, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-15K09647
[Journal Article] ALDH2 polymorphism in patients with Diamond-Blackfan anemia in Japan.2016
- Author(s)
  Ikeda F, Toki T, Kanezaki R, Terui K, Yoshida K, Kanno H, Ohga S, Ohara A, Kojima S, Ogawa S, Ito E.
- Journal Title
  
  Int J Hematol.
  
  Volume: 103 Issue: 1 Pages: 112-114
- DOI
  10.1007/s12185-015-1891-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-25461609, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K10041
[Journal Article] Erythrocyte glutathione is a novel biomarker of Diamond-Blackfan anemia2016
- Author(s)
  Utsugisawa T, Uchiyama T, Toki T, Ogura H, Aoki T, Hamaguchi I, Ishiguro A, Ohara A, Kojima S, Ohga S, Ito E, Kanno H
- Journal Title
  
  Blood Cells, Molecules and Diseases
  
  Volume: 59 Pages: 31-36
- DOI
  10.1016/j.bcmd.2016.03.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461609, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-16K10041
[Journal Article] Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan.2016
- Author(s)
  Taga T, Watanabe T, Tomizawa D, Kudo K, Kiminori Terui K, Moritake H, Kinoshita A, Iwamoto S, Nakayama H, Takahashi H, Shimada A MD, Taki T, Toki T, Ito E, Goto H, Koh K, Saito AM, Horibe K, Nakahata T, Tawa A, Adachi S.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 63 Issue: 2 Pages: 248-54
- DOI
  10.1002/pbc.25789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15384, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15K09486
[Journal Article] Systematic cellular disease models reveal synergistic interactions of trisomy 21 and GATA1 mutations in hematopoietic abnormalities2016
- Author(s)
  K. Banno, S. Omori, K. Hirata, N. Nawa, N. Nakagawa, K. Nishimura, M. Ohtaka, M. Nakanishi, T. Sakuma, T. Yamamoto, T. Toki, E. Ito, T. Yamamoto, C. Kokubu, J. Takeda, H. Taniguchi, H. Arahori, K. Wada, Y. Kitabatake and K. Ozono
- Journal Title
  
  Cell Reports
  
  Volume: 15 Issue: 6 Pages: 1-15
- DOI
  10.1016/j.celrep.2016.04.031
- NAID
  120007135439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461583, KAKENHI-PROJECT-14J04075, KAKENHI-PROJECT-24591601, KAKENHI-PROJECT-25461546, KAKENHI-PROJECT-25461643, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15K15384, KAKENHI-PROJECT-26860799, KAKENHI-PROJECT-16K10090, KAKENHI-PROJECT-16K18478
[Journal Article] ダウン症候群に伴うTAM発症の分子機構2015
- Author(s)
  照井君典, 金崎里香, 土岐力, 伊藤悦朗
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 25 Pages: 49-54
- Data Source
  KAKENHI-PROJECT-26461559
[Journal Article] Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.2015
- Author(s)
  Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, et al.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 168 Issue: 6 Pages: 854-864
- DOI
  10.1111/bjh.13229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591556, KAKENHI-PROJECT-25291003, KAKENHI-PROJECT-25461601, KAKENHI-PROJECT-25461609, KAKENHI-PROJECT-25860798, KAKENHI-PROJECT-26253061
[Journal Article] Transient myeloproliferative disorder with partial trisomy 21.2015
- Author(s)
  Takahashi T, Inoue A, Yoshimoto J, Kanamitsu K, Taki T, Imada M, Yamada M, Ninomiya S, Toki T, Terui K, Ito E, Shimada A.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 62 Issue: 11 Pages: 2021-2024
- DOI
  10.1002/pbc.25624
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09486, KAKENHI-PROJECT-15K15384, KAKENHI-PROJECT-26253061
[Journal Article] Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children.2015
- Author(s)
  1. Ono R, Hasegawa D, Hirabayashi S, Kamiya T, Yoshida K, Yonekawa S, Ogawa C, Hosoya R, Toki T, Terui K, Ito E, Manabe A.
- Journal Title
  
  Eur J Pediatr.
  
  Volume: 174 Issue: 4 Pages: 525-531
- DOI
  10.1007/s00431-014-2430-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26253061
[Journal Article] Gene alterations involving the CRLF2-JAK pathway and recurrent gene deletions in Down syndrome-associated acute lymphoblastic leukemia in Japan.2014
- Author(s)
  Hanada I, Terui K, Ikeda F, Toki T, Kanezaki R, Sato T, Kamio T, Kudo K, Sasaki S, Takahashi Y, Hayashi Y, Inukai T, Kojima S, Koike K, Kosaka Y, Kobayashi M, Imaizumi M, Mitsui T, Hori H, Hara J, Horibe K, Nagai J, Goto H, Ito E.
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 53 Issue: 11 Pages: 902-910
- DOI
  10.1002/gcc.22201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24591539, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-26461560, KAKENHI-PROJECT-26461598, KAKENHI-PROJECT-26461599
[Journal Article] 非ダウン症小児急性巨核芽球性白血病にみとめられた新規GATA1インフレーム変異2014
- Author(s)
  王汝南, 金崎里香, 土岐力, 照井君典, 佐々木伸也, 工藤耕, 神尾卓哉, 佐藤知彦, 池田史圭, 荒木亮, 落合英俊, 伊藤悦朗
- Journal Title
  
  弘前医学
  
  Volume: 65 Pages: 227-237
- NAID
  110009838312
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461559
[Journal Article] 非ダウン症小児急性巨核芽球性白血病にみとめられた新規GATA1インフレーム変異2014
- Author(s)
  王汝南, 金崎里香, 土岐力, 照井君典, 佐々木伸也, 工藤耕, 神尾卓哉, 佐藤智彦, 池田史圭, 荒木亮, 落合英俊, 伊藤悦朗
- Journal Title
  
  弘前医学
  
  Volume: 65 Pages: 227-237
- NAID
  110009838312
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461579
[Journal Article] Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome2013
- Author(s)
  Saida S, Watanabe K, Sato-Otsubo A, Terui K, Yoshida K, Okuno Y, Toki T, Wang R, Shiraishi Y, Miyano S, Kato I, Morishima T, Fujino H, Umeda K, Hiramatsu H, Adachi S, Ito E, Ogawa S, Ito M, Nakahata T, Heike T.
- Journal Title
  
  Blood
  
  Volume: 121 Pages: 4377-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] The landscape of somatic mutations in Down syndrome-related myeloid disorders.2013
- Author(s)
  Yoshida K
- Journal Title
  
  Nature Genet.
  
  Volume: 45 Issue: 11 Pages: 1293-1200
- DOI
  10.1038/ng.2759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-22134006, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23390273, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24390262, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-24700272, KAKENHI-PROJECT-24791054, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670446, KAKENHI-PROJECT-25670482
[Journal Article] The landscape of somatic mutations in Down syndrome-related myeloid disorders2013
- Author(s)
  Yoshida K, Toki T, Okuno Y, Kanezaki R, Shiraishi Y, Sato-Otsubo A, Sanada M, Park MJ, Terui K, Suzuki H, Kon A, Nagata Y, Sato Y, Wang R, Shiba N, Chiba K, Tanaka H, Hama A, Muramatsu H, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kato K, Nishimura R, Izraeli S, Hayashi Y, Miyano S, Kojima S, Ito E, Ogawa S.
- Journal Title
  
  Nat Genet
  
  Volume: 45 Pages: 1293-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome.2013
- Author(s)
  Saida, S., K. Watanabe, A. Sato-Otsubo, K. Terui, K. Yoshida, Y. Okuno, T. Toki, R. Wang, Y. Shiraishi, S. Miyano, I. Kato, T. Morishima, H. Fujino, K. Umeda, H. Hiramatsu, S. Adachi, E. Ito, S. Ogawa, M. Ito, T. Nakahata, and T. Heike.
- Journal Title
  
  Blood
  
  Volume: 121 Issue: 21 Pages: 4377-4387
- DOI
  10.1182/blood-2012-12-474387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23890092, KAKENHI-PROJECT-24659496, KAKENHI-PLANNED-22134006
[Journal Article] ダウン症候群関連急性リンパ性白血病におけるJAK2およびCRLF2遺伝子異常2013
- Author(s)
  照井君典,花田勇,土岐力,伊藤悦朗
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 50 Pages: 11-14
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome2013
- Author(s)
  Toki T, Kanezaki R, Kobayashi E, Kaneko H, Suzuki M, Wang R, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adachi S, Hayashi Y, Yamamoto M, Shimizu R, Ito E.
- Journal Title
  
  Blood
  
  Volume: 121(16) Issue: 16 Pages: 3181-3184
- DOI
  10.1182/blood-2012-01-405746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23390273, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24790957, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482, KAKENHI-PUBLICLY-23118501
[Journal Article] 新生児科医のためのTAM診療ガイドラインTAM発症の分子機構2013
- Author(s)
  伊藤悦朗,金崎理香,王汝南,照井君典,土岐力
- Journal Title
  
  日本周産期・新生児医学会雑誌
  
  Volume: 49 Pages: 20-22
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome2013
- Author(s)
  Toki T, Kanezaki R, Kobayashi E, Kaneko H, Suzuki M, Wang R, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adachi S, Hayashi Y, Yamamoto M, Shimizu R, Ito E.
- Journal Title
  
  Blood
  
  Volume: 121 Pages: 3181-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Down syndrome associated myeloid disorders2013
- Author(s)
  伊藤悦朗,土岐力
- Journal Title
  
  血液フロンティア
  
  Volume: 24 Pages: 47-53
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Down症に伴う骨髄増殖症2012
- Author(s)
  伊藤悦朗,土岐力
- Journal Title
  
  日本臨床
  
  Volume: 70 Pages: 687-91
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia2012
- Author(s)
  Takashi Yokoyama, Tsutomu TokiTakashi Yokoyama, Tsutomu Toki, Yoshihiro Aoki, Rika Kanezaki, Myoung-ja Park, Yohei Kanno, Myoung-ja Park, Yohei Kanno, Etsuro Ito, Yasuhide Hayashi, Takuro Nakamura
- Journal Title
  
  Blood
  
  Volume: 119(11) Pages: 208-2611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591344
[Journal Article] Extensive gene deletions in Japanese patients with Diamond-Blackfananemia2012
- Author(s)
  Kuramitsu M, Toki T, Ito E, 他22名
- Journal Title
  
  Blood
  
  Volume: 119(10) Pages: 2376-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390266
[Journal Article] A novel mutation of ribosomal protein S10 gene in a Japanese patient with diamond-Blackfan anemia2012
- Author(s)
  Yazaki M, Kamei M, Ito Y, Konno Y, Wang R, Toki T, Ito E.
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 34 Pages: 293-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] A novel mutation of ribosomal protein s10 gene in a Japanese patient with diamond-blackfan anemia2012
- Author(s)
  Yazaki M, Kamei M, Ito Y, Konno Y, Wang R, Toki T, Ito E
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 34(4) Issue: 4 Pages: 293-5
- DOI
  10.1097/mph.0b013e31824a20ab
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390266, KAKENHI-PUBLICLY-23118501
[Journal Article] Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia2012
- Author(s)
  Kuramitsu M, Sato-Otsubo A, Morio T, Takagi M, Toki T, Terui K, Wang R, Kanno H, Ohga S, Ohara A, Kojima S, Kitoh T, Goi K, Kudo K, Matsubayashi T, Mizue N, Ozeki M, Masumi A, Momose H, Takizawa K, Mizukami T, Yamaguchi K, Ogawa S, Ito E, Hamaguchi I.
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 2376-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia2012
- Author(s)
  Yokoyama T, Toki T, Aoki Y, Kanezaki R, Park MJ, Kanno Y, Takahara T, Yamazaki Y, Ito E, Hayashi Y, Nakamura T.
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 11 Pages: 2608-2611
- DOI
  10.1182/blood-2010-12-324806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-23790451, KAKENHI-PROJECT-24390268, KAKENHI-PUBLICLY-23118501
[Journal Article] Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia2012
- Author(s)
  Yokoyama T, Toki T, Ito E, 他7名
- Journal Title
  
  Blood
  
  Volume: 119(11) Pages: 2608-2611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390266
[Journal Article] 一過性骨髄異常増殖症(TAM)発症の分子機構2011
- Author(s)
  土岐力,伊藤悦朗
- Journal Title
  
  日本小児血液学会雑誌
  
  Volume: 25 Pages: 171-8
- Data Source
  KAKENHI-PROJECT-23591527
[Journal Article] Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia2011
- Author(s)
  Kuramitsu M, Matsubara A, Morio T, Takagi M, Toki T, Terui K, RuNan W, Kanno H, Ohga S, Ohara A, Kitoh T, Sugita K, Kudo K, Matsubayashi T, Mizue N, Ozeki M, Masumi A, Momose H, Takizawa K, Mizukami T, Yamaguchi K, Ogawa S, Ito E, Hamaguchi I
- Journal Title
  
  Blood
  
  Volume: (in press) Issue: 10 Pages: 2376-84
- DOI
  10.1182/blood-2011-07-368662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591388, KAKENHI-PROJECT-22591071, KAKENHI-PROJECT-22790922, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23791093, KAKENHI-PROJECT-23791162, KAKENHI-PUBLICLY-23118501
[Journal Article] Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia.2010
- Author(s)
  Kanezaki R, Toki T, Terui K, Xu G, Wang RN, Shimada A, Hama A, Kanegane H, Kawakami K, Endo M, Hasegawa D, Kogawa K, Adachi S, Ikeda Y, Iwamoto S, Taga T, Kosaka Y, Kojima S, Hayashi Y, Ito E.
- Journal Title
  
  Blood 116(22)
  
  Pages: 4631-8
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia.2010
- Author(s)
  Konno Y, Toki T, Tandai S, Xu G, Wang R, Terui K, Ohga S, Hara T, Hama A, Kojima S, Hasegawa D, Kosaka Y, Yanagisawa R, Koike K, Kanai R, Imai T, Hongo T, Park MJ, Sugita K, Ito E
- Journal Title
  
  Haematologica 95
  
  Pages: 1293-1299
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] Molecular pathogenesis in Diamond-Blackfan anemia.2010
- Author(s)
  Ito E, Konno Y, Toki T, Terui K
- Journal Title
  
  Int J Hematol 92
  
  Pages: 413-418
- NAID
  10027673188
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] Molecular pathogenesis in Diamond-Blackfan anemia2010
- Author(s)
  Ito E, Konno Y, Toki T, Terui K.
- Journal Title
  
  Int J Haematol
  
  Volume: 92(3) Pages: 413-418
- NAID
  10027673188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] Molecular pathogenesis in Diamond-Blackfan anemia (review).2010
- Author(s)
  Ito E, Konno Y, Toki T, Terui K
- Journal Title
  
  Int J Hematol. 92(3)
  
  Pages: 413-8
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder : mutation classes correlate with progression to myeloid leukemia.2010
- Author(s)
  Kanezaki R, Toki T, Terui K, Xu G, Wang R, Shimada A, Hama A, Kanegane H, Kawakami K, Endo M, Hasegawa D, Kogawa K, Adachi S, Ikeda Y, Iwamoto S, Taga T, Kosaka Y, Kojima S, Hayashi Y, Ito E
- Journal Title
  
  Blood 116
  
  Pages: 4631-4638
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder : mutation classes correlate with progression to myeloid leukemia2010
- Author(s)
  Rika Kanezaki, Tsutomu Toki, Kiminori Terui, Gang Xu, RuNan Wang, Akira Shimada, Asahito Hama, Hirokazu Kanegane, Kiyoshi Kawakami, Mikiya Endo, Daisuke Hasegawa, Kazuhiro Kogawa, Souichi Adachi, Yasuhiko Ikeda, Shotaro Iwamoto, Takashi Taga, Yoshiyuki Kosaka, Seiji Kojima, Yasuhide Hayashi, Etsuro ItoAdachi, Yasuhiko Ikeda, Shotaro Iwamoto, Takashi Taga, Yoshiyuki Kosaka, Seiji Kojima, Yasuhide Hayashi, Etsuro Ito
- Journal Title
  
  Blood
  
  Volume: 116(22) Pages: 4631-4638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591344
[Journal Article] Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia.2010
- Author(s)
  Konno Y, Toki T, Tandai S, Xu G, Wang RN, Terui K, Ohga S, Hara T, Hama A, Kojima S, Hasegawa D, Kosaka Y, Yanagisawa R, Koike K, Kanai R, Imai T, Hongo T, Park MJ, Sugita K, Ito E
- Journal Title
  
  Haematologica 95(8)
  
  Pages: 1293-9
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia.2010
- Author(s)
  Konno Y, Toki T, Tandai S, Xu G, Wang RN, Terui K, Ohoga S, Hara T, Hama A, Kojima S, Hasegawa D, Kosaka Y, Yanagisawa R, Koike K, Kanai R, Imai T, Hongo T, Park MJ, Sugita K, Ito E.
- Journal Title
  
  Haematologica (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] 小児科領域の血液疾患一過性骨髄増殖性疾患2009
- Author(s)
  伊藤悦朗,土岐力,金崎理香,佐藤知彦,照井君典,足立壮一
- Journal Title
  
  日本検査血液学会雑誌 10
  
  Pages: 457-464
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia.2009
- Author(s)
  Toki T, Ito E, et. al.
- Journal Title
  
  Leukemia 23巻
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia2009
- Author(s)
  Toki T Ito E, et.al.
- Journal Title
  
  Leukemia 23
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia.2009
- Author(s)
  Toki T, Kanezaki R, Adachi S, Fujino H, Xu G, Sato T, Suzuki K, Tauchi H, Endo M, Ito E
- Journal Title
  
  Leukemia 23
  
  Pages: 95-103
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] The key role of stem cell factor/KIT signaling in the prolife ration of blast cells from Down syndrome-related leukemia2009
- Author(s)
  Tsutomu TOKI
- Journal Title
  
  Leukemia 23
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591236
[Journal Article] The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia.2009
- Author(s)
  Toki T, Ito E, et al.
- Journal Title
  
  Leukemia 23
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] 一過性骨髄増殖症2009
- Author(s)
  土岐力
- Journal Title
  
  小児疾患診療のための病態生理小児内科増刊号 41
  
  Pages: 1183-1186
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] 一過性骨髄増殖症.小児疾患診療のための病態生理2009
- Author(s)
  土岐力、照井君典、伊藤悦朗
- Journal Title
  
  小児内科増刊号 41
  
  Pages: 1183-1186
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia2009
- Author(s)
  Toki T, Ito E, et al.
- Journal Title
  
  Leukemia 23
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome.2008
- Author(s)
  Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kanegane H, Miura M, Adachi S, Migita M, Morinaga S, Nakano T, Endo M, Kojima S, Kiyoi H, Mano H, Ito E
- Journal Title
  
  Br J Haematol 141
  
  Pages: 681-688
- Data Source
  KAKENHI-PROJECT-20591241
[Journal Article] Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome.2008
- Author(s)
  Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kanegane H, Miura M, Adachi S, Migita M, Morinaga S, Nakano T, Endo M, Kojima S, Kiyoi H, Mano H, Ito E
- Journal Title
  
  Brit J Haematol. 141
  
  Pages: 681-688
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome.2008
- Author(s)
  Sato T, Toki T, Kanezaki R, Ito E, at. al.
- Journal Title
  
  Brit J Haematol 141巻
  
  Pages: 681-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Functional analysis of JAK3 mutations in transient myelopro liferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome2008
- Author(s)
  Sato T, Toki T, Kanezaki R, Ito E et. al.
- Journal Title
  
  Brit J Haematol 141
  
  Pages: 681-688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome.2008
- Author(s)
  Sato T, Toki T, Ito E et a1.
- Journal Title
  
  Brit J Haematol. 141
  
  Pages: 681-688
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia2008
- Author(s)
  Tsutomu Toki, Rika Kanezaki, Souichi Adachi, Hisanori Fujino, Gang Xu, Tomohiko Sato, Kahori Suzuki, Hisamichi Tauchi, Mikiya Endo, Etsuro Ito
- Journal Title
  
  Leukemia 23巻
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591236
[Journal Article] Functional analysis of JAK3 mutations in transient myeloproliferative disorder order and acute megakaryoblastic leukemia accompanying Down syndrome2008
- Author(s)
  Sato T, Toki T, Kanezaki R, Ito E, et.al.
- Journal Title
  
  But J Haematol 141
  
  Pages: 681-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390289
[Journal Article] Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen2007
- Author(s)
  Tono C, Ito E, Toki T, et. al.
- Journal Title
  
  Bone Marrow Transplant. 39
  
  Pages: 801-804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Leukemia (leukemia-related disorders)2007
- Author(s)
  Ito E, Toki T.
- Journal Title
  
  New Diagnosis and Treatment of Pediatric Malignancy (In Bessho F, Sugimoto T and Yokomori K(eds).) (Shindan To Chiryo Sha)
  
  Pages: 217-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Molecular mechanism of Down syndrome-related A cute Megakaryoblastic Leukemia2007
- Author(s)
  Ito E, Toki T.
- Journal Title
  
  Hematological Oncology (In Ohno R(eds). Nippon Rinsho Sha)
  
  Pages: 728-732
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen.2007
- Author(s)
  Tono C, Takahashi Y, Toki T, Ito E , et. al.
- Journal Title
  
  Bone Marrow Transplant. 39
  
  Pages: 801-804
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Development of Acute Megakaryoblastic Leukemia From a Minor Clone in a Down Syndrome Patient With Clinically Overt Transient Myeloproliferative Disorder2006
- Author(s)
  Xu G, Kato K, Toki T, Takahashi Y, Terui K, Ito E
- Journal Title
  
  J Pediatr Hematol Oncol. 28
  
  Pages: 696-698
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Cloning and Characterization of the Novel Chimeric Gene p53/FXR2 in the Acute Megakaryoblastic Leukemia Cell Line CMK11-52006
- Author(s)
  Kanezaki R, Toki T, Xu G, Narayanan R, Ito E.
- Journal Title
  
  Tohoku J Exp Med 209
  
  Pages: 169-80
- NAID
  10019253497
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Development of Acute Megakaryoblastic Leukemia From a Minor Clone in a Down Syndrome Patient With Clinically Overt Transient Myeloproliferative Disorder.2006
- Author(s)
  Xu G, Kato K, Toki T, Ito E, et. al.
- Journal Title
  
  J Pediatr Hematol Oncol. 28
  
  Pages: 696-698
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Cloning and Characterization of the novel chimeric gene p53/FXR2 in the acute megakaryoblastic leukemia cell line CMK 11-52006
- Author(s)
  R.Kanezaki, T.Toki, G.Xu, R.Narayanan, E.Ito
- Journal Title
  
  Tohoku J. Exp. Med 209・3
  
  Pages: 169-180
- NAID
  10019253497
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome.2006
- Author(s)
  G.Xu, R.Kanezaki, T.Toki, S.Watanabe, Y.Takahashi, K.Terui, I.Kitabayashi, Ito E.
- Journal Title
  
  Leukemia 20・6
  
  Pages: 1002-1008
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Development of A cute Megakaryoblastic Leukemia From a Minor Clone in a Down Syndrome Patient With Clinically Overt Transient Myeloproliferative Disorder2006
- Author(s)
  Xu G, Kato K, Toki T, Takahashi Y, Terui K, Ito E.
- Journal Title
  
  J Pediatr Hematol Oncol 28
  
  Pages: 696-698
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome.2006
- Author(s)
  Xu G, Kanezaki R, Toki T, Watanabe S, Takahashi Y, Terui K, Kitabayashi I, Ito E.
- Journal Title
  
  Leukemia 20巻
  
  Pages: 1002-1008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome2006
- Author(s)
  Xu G, Kanezaki R, Toki T, Watanabe S, Ito E et. al.
- Journal Title
  
  Leukemia 20
  
  Pages: 1002-1008
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Cloning and Characterization of the Novel Chimeric Gene p53/FXR2 in the Acute Megakaryoblastic Leukemia Cell Line CMK11-5.2006
- Author(s)
  Kanezaki R, Toki T, Xu G, Narayanan R, Ito E.
- Journal Title
  
  Tohoku J Exp Med. 209巻
  
  Pages: 169-180
- NAID
  10019253497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Development of Acute Megakaryoblastic Leukemia From a Minor Clone in a Down Syndrome Patient With Clinically Overt Transient Myeloproliferative Disorder2006
- Author(s)
  Xu G, Kato K, Toki T, Takahashi Y, Terui K, Ito E
- Journal Title
  
  J Pediatr Hematol Oncol. 28
  
  Pages: 696-698
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Cloning and Charaterization of the novel chimeric gene p53/FXR2 in the acute megakaryoblastic leukemia cell line CMK 11-52006
- Author(s)
  R.Kanezaki, T.Toki, G.Xu, R.Narayanan, E.Ito
- Journal Title
  
  Tohoku J. Exp. Med 209・3
  
  Pages: 169-180
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome.2006
- Author(s)
  Xu G, Kanezaki R, Toki T, Takahashi Y, Ito E , et. al.
- Journal Title
  
  Leukemia 20
  
  Pages: 1002-1008
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Physical association of the patient-specitic GATAI mutants with RUNXI in acute megakaryoblastic leukemia accompanying Down syndrome.2006
- Author(s)
  G.Xu, R.Kanezaki, T.Toki, S.Watanabe, Y.Takahashi, K.Terui, I.Kitabayashi, Ito E.
- Journal Title
  
  Leukemia 20・6
  
  Pages: 1002-1008
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Development Acute Megakaryoblastic Leukemia From a Minor Clone in a Down Syndrome Patient With Clinically Overt Transient Myeloproliferative Disorder.2006
- Author(s)
  Xu G, Kato K, Toki T, Takahashi Y, Terui K, Ito E.
- Journal Title
  
  J Pediatr Hematol Oncol 28巻
  
  Pages: 696-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Cloning and Characterization of the Novel Chimeric Gene p53/FXR2 in the Acute Megakaryoblastic Leukemia Cell Line CMK11-5.2006
- Author(s)
  Kanezaki R, Toki T, Ito E, et. al.
- Journal Title
  
  Tohoku J Exp Med 209
  
  Pages: 169-180
- NAID
  10019253497
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] JAK2 Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia2005
- Author(s)
  Tono C, Xu G, Toki T, Takahashi Y, Sasaki S, Terui K, and Ito E.
- Journal Title
  
  Leukemia 19
  
  Pages: 1843-1844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] JAK2 Val617 Pheactivating tyrosine kinase mutation in juvenile myelomonocytic leukemia.2005
- Author(s)
  Tono C, Xu G, Toki T, Takahashi Y, Sasaki S, Terui K, Ito E.
- Journal Title
  
  Leukemia 19巻
  
  Pages: 1843-1844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Transgenic expression of BACH1 transcription factor esults in megakaryocytic impairment.2005
- Author(s)
  Tsutomu Toki
- Journal Title
  
  Blood 105
  
  Pages: 3100-3108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591079
[Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  Toki T, Katsuoka F, Kanezaki R, Xu G, Kurotaki H, Sun J, Kamio T, Watanabe S, Tandai S, Terui K, Yagihashi S, Komatsu N, Igarashi K, Yamamoto M, Ito E.
- Journal Title
  
  Blood 105巻
  
  Pages: 3100-3108
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] JAK2 Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia2005
- Author(s)
  Tono C, Xu G, Toki T, Takahashi Y, Sasaki S, Terui K, Ito E.
- Journal Title
  
  Leukemia 19・10
  
  Pages: 1843-1844
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] JAK2 Va1617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia.2005
- Author(s)
  Tono C, Xu G, Toki T, Ito E , et. al.
- Journal Title
  
  Leukemia 19
  
  Pages: 1843-1844
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment2005
- Author(s)
  Tsutomu Toki
- Journal Title
  
  BLOOD 105
  
  Pages: 3100-3108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591079
[Journal Article] The proto-oncogene ERG in megakaryoblastic leukemias.2005
- Author(s)
  Rainis L, Toki T, Pimanda JE, Rosenthal E, Machol K, Strehl S, Gottgens B, Ito E, Izraeli S.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7596-7602
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment2005
- Author(s)
  Toki T, Katsuoka F, Kanezaki R, Xu G, Ito E et. al.
- Journal Title
  
  Blood 105
  
  Pages: 3100-3108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  Toki T, Katsuoka F, Kanezaki R, Xu G, Ito E , et. al.
- Journal Title
  
  Blood 105
  
  Pages: 3100-3108
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment2005
- Author(s)
  Toki T, Katsuoka F, Ito E et al.
- Journal Title
  
  Blood 105
  
  Pages: 3100-3108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] The proto-oncogene ERG in megakaryoblastic leukemias.2005
- Author(s)
  Rainis L, Toki T, Ito E , et. al.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7596-7602
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  Toki T, Katusuoka F, Kanezaki R, Xu G, Kurotaki H, Sun J, Kamio T, Watanabe S, Tandai S, Terui K, Yagihashi S, Komatsu N, Igarashi K, Yamamoto M, Ito E.
- Journal Title
  
  Blood 105
  
  Pages: 3100-3108
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] JAK2 Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia2005
- Author(s)
  Tono C, Xu G, Toki T, Takahashi Y, Sasaki S, Terui K, Ito E.
- Journal Title
  
  Leukemia 19・10
  
  Pages: 1843-1844
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  Toki T, Katsuoka F, Kanezaki R, Xu G, Kurotaki H, Sun J, Kamio T, Watanabe S, Tandai S, Terui K, Yagihashi S, Komatsu N, Igarashi K, Yamamoto M, Ito E.
- Journal Title
  
  Blood 105
  
  Pages: 3100-3108
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  Toki T, Katsuoka F, et al.
- Journal Title
  
  Blood 105(8)
  
  Pages: 3100-3108
- Data Source
  KAKENHI-PROJECT-17591066
[Journal Article] The proto-oncogene ERG in megakaryoblastic leukemias.2005
- Author(s)
  Rainis L, Toki T, Pimanda JE, Rosenthal E, Machol K, Strehl S, Gottgens B, Ito E, Izraeli S.
- Journal Title
  
  Cancer Res. 65巻
  
  Pages: 7596-7602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] The proto-oncogene ERG in megakaryoblastic leukemias2005
- Author(s)
  Rainis L, Toki T, Pimanda JE, Rosenthal E, Ito E et. al.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7596-7602
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] The proto-oncogene ERG in megakaryoblastic leukemias.2005
- Author(s)
  Rainis L, Toki T, Pimanda JE, Rosenthal E, Machol K, Strehl S, Gottgens B, Ito E, Izraeli S.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7596-7602
- Data Source
  KAKENHI-PROJECT-17390295
[Journal Article] Fetal origin of the GATA-1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down's syndrome.2004
- Author(s)
  Shimada A, Toki T, Ito E et al.
- Journal Title
  
  Blood 103・1
  
  Pages: 366-366
- Data Source
  KAKENHI-PROJECT-16022203
[Journal Article] The GATA-1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down's syndrome.2004
- Author(s)
  Harigae H, Toki T, Ito E et al.
- Journal Title
  
  Blood 103
  
  Pages: 3242-3243
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] The GATA-1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down's syndrome2004
- Author(s)
  Harigae H, Toki T, Ito E et al.
- Journal Title
  
  Blood 103
  
  Pages: 3242-3243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] Fetal origin of the GATA-1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down's syndrome.2004
- Author(s)
  Shimada A, Toki T, Ito E et al.
- Journal Title
  
  Blood 103・1
  
  Pages: 366-366
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] The GATA-1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down's syndrome.2004
- Author(s)
  Harigae H, Toki T, Ito E et al.
- Journal Title
  
  Blood 103・8
  
  Pages: 3242-3243
- Data Source
  KAKENHI-PROJECT-16022203
[Journal Article] The GATA-1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down's syndrome.2004
- Author(s)
  Harigae H, Toki T, Ito E et al.
- Journal Title
  
  Blood 103・8
  
  Pages: 3242-3243
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] Fetal origin of the GATA-1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down's syndrome.2004
- Author(s)
  Shimada A, Toki T, Ito E et al.
- Journal Title
  
  Blood 103
  
  Pages: 366-366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] The B cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs.2003
- Author(s)
  Kamio T, Toki T, Terui K, Ito E et al.
- Journal Title
  
  Blood 102
  
  Pages: 3317-3322
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down's syndrome.2003
- Author(s)
  Xu G, Toki T, Ito E et al.
- Journal Title
  
  Blood 102・8
  
  Pages: 2960-2968
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down's syndrome.2003
- Author(s)
  Xu G, Toki T, Ito E et al.
- Journal Title
  
  Blood 102
  
  Pages: 2960-2968
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] The B cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs.2003
- Author(s)
  Kamio T, Toki T, Terui K, Ito E et al.
- Journal Title
  
  Blood 102・9
  
  Pages: 3317-3322
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] The B cell-specific transcription factor BACH2 modifies the cytotoxic effects of ticancer drugs.2003
- Author(s)
  Kamio T, Toki T, Terui K, Ito E et al.
- Journal Title
  
  Blood 102
  
  Pages: 3317-3322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370238
[Journal Article] Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome
- Author(s)
  Sato T, Toki T, Ito E, et. al.
- Journal Title
  
  Brit J Haematol (In press)
- Data Source
  KAKENHI-PROJECT-17013004
[Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment
- Author(s)
  Toki T, Ito E et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-16659268
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.
- Author(s)
  Toki T, Katsuoka F, Ito E et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-16022203
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.
- Author(s)
  Toki T, Katsuoka F, Ito E et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-14370238
[Presentation] Clinical characteristics of infants with transient abnormal myelopoiesis and two GATA1 mutations: A report from the JPLSG TAM-10 study2023
- Author(s)
  Kana Soma, Tomohiko Sato, Tsutomu Toki, Rika Kanezaki, Ko Kudo, Genki Yamato, Hideki Muramatsu, Kenichiro Watanabe, Etsuro Ito, Kiminori Terui
- Organizer
  第65回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07790
[Presentation] BRAFV600E-POSITIVE PRECURSORS AS MOLECULAR MARKERS OF BONE MARROW INVOLVEMENT IN PEDIATRIC LANGERHANS CELL HISTIOCYTOSIS.2019
- Author(s)
  Ko Kudo, Rika Kanezaki, Masaru Imamura, Chihaya Imai, Masahiro Irie, Yoji Sasahara, Kumiko Ando, Harumi Kakuda, Takehiko Doi, Hiroshi Kawaguchi, Kazuko Kudo, Hirokazu Kanegane, Tsutomu Toki, and Etsuro Ito.
- Organizer
  35th Annual Meeting of the Histiocyte Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039
[Presentation] Post-induction minimal residual disease measured by flow cytometry and deep sequencing of mutant GATA1 are both significant prognostic factors for children with myeloid leukemia and Down syndrome: a nationwide prospective study of the Japanese Pediatric Leukemia/Lymphoma Study Group.2019
- Author(s)
  Takashi Taga, Shiro Tanaka,, Kiminori Terui, Tsutomu Toki, Etsuro Ito, et al.
- Organizer
  American Society of Hematology 61th Annual Meetin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039
[Presentation] ダイアモンド・ブラックファン貧血におけるミスセンス変異の新規機能解析法2019
- Author(s)
  小林明恵, 金崎里香, 池田史圭, 佐藤知彦, 照井君典, 佐々木伸也, 工藤耕, 神尾卓哉, 土岐力, 伊藤悦朗
- Organizer
  第81回日本血液学会
- Data Source
  KAKENHI-PROJECT-17K10093
[Presentation] ダウン症児に発症する巨核芽球性白血病におけるエピゲノム異常2018
- Author(s)
  渡辺　亮、才田　聡、中村　正裕、土岐　力、金崎　里香、照井　君典、渡邉　健一郎、伊藤　悦朗
- Organizer
  第80回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04039
[Presentation] Integrated genetic and epigenetic analysis elucidated expression and methylation profiles of acute lymphoblastic leukemia in Down syndrome2018
- Author(s)
  Yasuo Kubota, Kumiko Uryu, Tatsuya Ito, Tomoko Kawai, Masafumi Seki, Tomoya Isobe, Tsutomu Toki, Kenichi Yoshida, Keisuke Kataoka, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Akira Oka, Yasuhide Hayashi, Seishi Ogawa, Kiminori Terui, Atsushi Sato, Kenichiro Hata, Etsuro Ito, Junko Takita.
- Organizer
  The 23th Congress of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039
[Presentation] ダイアモンド・ブラックファン貧血におけるリボソーム蛋白遺伝子のGATA1結合部位の変異解析2018
- Author(s)
  小林明恵, 久保かほり, 金崎里香, 佐藤知彦, 土岐力, 伊藤悦朗, 他
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10093
[Presentation] Integrated genetic/epigenetic analysis revealed high heterogeneity of acute lymphoblastic leukemia in Down syndrome2017
- Author(s)
  Yasuo Kubota, Kumiko Uryu, Tatsuya Ito, Tomoko Kawai, Masafumi Seki, Tomoya Isobe, Tsutomu Toki, Kenichi Yoshida, Keisuke Kataok), Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Akira Oka, Yasuhide Hayashi, Seishi Ogawa, Kiminori Terui, Atsuhi Sato, Kenichiro Hata, Etsuro Ito, Junko Takita
- Organizer
  59th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] Clinical impact of GATA1 mutation types in infants with Down syndrome and TAM: JPLSG TAM-10 study.2017
- Author(s)
  Kiminori Terui, Tsutomu Toki, Asahito Hama, Hideki Muramatsu, Daisuke Hasegawa, Myoung-ja Park, Shotaro Iwamoto, Takashi Taga, Ryu Yanagisawa, Katsuyoshi Koh, Akiko M. Saito, Keizo Horibe, Yasuhide Hayashi, Souichi Adachi Shuki Mizutani, Kenichiro Watanabe and Etsuro Ito
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] 本邦におけるDiamond-Blacfan 貧血の診断的ターゲットおよびエクソームシーケンス解析2017
- Author(s)
  土岐　力
- Organizer
  第79回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10093
[Presentation] Gene expression profiles and methylation analysis in Down syndrome related acute lymphoblastic leukemia2016
- Author(s)
  Kubota Y, Uryu K, Kawai T, Ito T, Hanada I, Toki T, Seki M, Yoshida K, Kataoka K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Oka A, Hayashi Y, Ogawa S, Terui K, Sato A, Hata K, Ito E and Takita J
- Organizer
  58th American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, United States of America
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461560
[Presentation] Analysis of GATA1 mutations in Down syndrome infants with transient abnormal myelopoiesis and clinical impacts of GATA1 mutation types: A report from the JPLSG TAM-10 study.2016
- Author(s)
  Kiminori Terui, Tsutomu Toki, Asahito Hama, Hideki Muramatsu, Daisuke Hasegawa, Myoung-ja Park, Shotaro Iwamoto, Takashi Taga, Ryu Yanagisawa, Katsuyoshi Koh, Akiko M. Saito, Keizo Horibe, Yasuhide Hayashi, Souichi Adachi Shuki Mizutani, Kenichiro Watanabe and Etsuro Ito
- Organizer
  American Society of Hematology 58th Annual Meeting
- Place of Presentation
  SanDiego, CA, USA
- Year and Date
  2016-12-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15384
[Presentation] Analysis of GATA1 mutations in Down syndrome infants with transient abnormal myelopoiesis and clinical impacts of GATA1 mutation types: A report from the JPLSG TAM-10 study.2016
- Author(s)
  Kiminori Terui, Tsutomu Toki, Asahito Hama, Hideki Muramatsu, Daisuke Hasegawa, Myoung-ja Park, Shotaro Iwamoto, Takashi Taga, Ryu Yanagisawa7, Katsuyoshi Koh, Akiko M. Saito, Keizo Horibe, Yasuhide Hayashi, Souichi Adachi, Shuki Mizutani, Kenichiro Watanabe and Etsuro Ito
- Organizer
  American Society of Hematology 58th Annual Meeting
- Place of Presentation
  SanDiego, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] Genetic and Epigenetic Alterations in Acute Megakaryoblastic Leukemia in Down Syndrome.2016
- Author(s)
  Etsuro Ito, Kenichi Yoshida, Tsutomu Toki, Satoshi Saida, Kenichiro Watanabe, Masahiro Nakamura, Kiminori, Terui, Tatsutoshi Nakahata, Satoru Miyano, Akira Watanabe, Seishi Ogawa
- Organizer
  Fifth JCA- AACR Special Joint Conference -The Latest Advances in Hematological Cancer Research: From Basic Science to Therapeutics.
- Place of Presentation
  Tokyo Bay Maihama Hotel, Urayasu, Chiba
- Year and Date
  2016-07-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15384
[Presentation] Dysregulation of the KIT gene expression by GATA1s in Down syndrome related myeloid disorders.2016
- Author(s)
  金崎里香, 土岐力, 照井君典, 佐々木伸也, 工藤耕, 神尾卓哉, 佐藤知彦, 池田史圭, 伊藤悦朗
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461559
[Presentation] 小児急性リンパ性白血病再発例に頻発するRAS経路の体細胞突然変異2016
- Author(s)
  久保かほり, 土岐力, 金崎里香, 伊東竜也, 池田史圭, 佐藤知彦, 神尾卓哉, 工藤耕, 佐々木伸也, 照井君典, 伊藤悦朗
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川プリンスホテル（東京都）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-26461560
[Presentation] Genetic and Epigenetic Alterations in Acute Megakaryoblastic Leukemia in Down Syndrome.2016
- Author(s)
  Etsuro Ito, Kenichi Yoshida, Tsutomu Toki, Satoshi Saida, Kenichiro Watanabe, Masahiro Nakamura, Kiminori, Terui, Tatsutoshi Nakahata, Satoru Miyano, Akira Watanabe, Seishi Ogawa
- Organizer
  Fifth JCA-AACR Special Joint Conference -The Latest Advances in Hematological Cancer Research: From Basic Science to Therapeutics.
- Place of Presentation
  Tokyo Bay Maihama Hotel, Urayasu, Chiba
- Year and Date
  2016-07-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] Gene expression profiles and methylation analysis in Down syndrome related acute lymphoblastic leukemia2016
- Author(s)
  Yasuo Kubota, Kumiko Uryu, Tomoko Kawai, Tatsuya Ito, Isamu Hanada, Tsutomu Toki, Masafumi Seki, Kenichi Yoshida, Yusuke Sato, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Akira Oka, Yasuhide Hayashi, Seishi Ogawa, Kiminori Teru), Atsushi Sato, Kenichiro Hata, Etsuro Ito, Junko Takita
- Organizer
  American Society of Hematology 58th Annual Meeting
- Place of Presentation
  SanDiego, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] ダウン症候群児における急性リンパ性白血病のメチル化解析2016
- Author(s)
  久保田泰央, 瓜生久美子, 河合智子, 伊東竜也, 花田勇, 土岐力, 関正史, 吉田健一, 佐藤悠佑, 白石友一, 千葉健一, 田中洋子, 宮野悟, 岡明, 林泰英, 小川誠司, 照井君典, 佐藤篤, 秦健一郎, 伊藤悦朗, 滝田順子
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川プリンスホテル（東京都）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-26461560
[Presentation] ダウン症候群関連急性リンパ性白血病におけるRAS経路の遺伝子変異2015
- Author(s)
  伊東竜也, 照井君典, 花田勇, 池田史佳, 土岐力, 金崎里香, 佐藤知彦, 神尾卓哉, 工藤耕, 佐々木伸也, 高橋良博, 林泰秀, 犬飼岳史, 堀浩樹, 伊藤悦朗
- Organizer
  第57回日本小児血液・がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル（山梨県・甲府市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26461560
[Presentation] DNA methylation state correlates with progression of myeloid leukemia in Down syndrome2015
- Author(s)
  Saida S, Nakamura M, Toki T, Arai Y, Terui K, Yoshida Y, Ogawa S, Nakahata T, Heike T, Watanabe K, Watanabe A, Ito E
- Organizer
  第57回アメリカ血液学会
- Place of Presentation
  オーランド（米国）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] Prospective study of 168 infants with transient abnormal myelopoiesis with Down syndrome: Japan Pediatric Leukemia/Lymphoma Study Group, TAM-10 study2015
- Author(s)
  Muramatsu H, Watanabe T, Hasegawa D, Park M, Iwamoto S, Taga T, Ito E, Toki T, Terui K, Yanagisawa R, Koh K, Saito A, Horibe K, Hayashi Y, Adachi S, Mizutani S, Watanabe K.
- Organizer
  第57回アメリカ血液学会
- Place of Presentation
  オーランド（米国）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15384
[Presentation] DNA methylation state correlates with progression of myeloid leukemia in Down syndrome.2015
- Author(s)
  Saida S, Nakamura M, Toki T, Arai Y, Terui K, Yoshida Y, Ogawa S, Nakahata T, Heike T, Watanabe K, Watanabe A, Ito E.
- Organizer
  第57回アメリカ血液学会
- Place of Presentation
  オーランド（米国）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15384
[Presentation] Prospective study of 168 infants with transient abnormal myelopoiesis with Down syndrome: Japan Pediatric Leukemia/Lymphoma Study Group, TAM-10 study2015
- Author(s)
  Muramatsu H, Watanabe T, Hasegawa D, Park M, Iwamoto S, Taga T, Ito E, Toki T, Terui K, Yanagisawa R, Koh K, Saito A, Horibe K, Hayashi Y, Adachi S, Mizutani S, Watanabe K
- Organizer
  第57回アメリカ血液学会
- Place of Presentation
  オーランド（米国）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061
[Presentation] RAS pathway mutations in Down syndrome-associated acute lymphoblastic leukemia in Japan2015
- Author(s)
  Ito T, Terui K, Hanada I, Ikeda F, Toki T, Kanezaki R, Sato T, Kamio T, Kudo K, Sasaki S, Takahashi Y, Hayashi Y, Inukai T, Hori H and Ito E
- Organizer
  57th American Sciety of Hematology Annual Meeting
- Place of Presentation
  Orlando, United States of America
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461560
[Presentation] Insight into the clonal evolution of Down syndrome-associated myeloid leukemia2015
- Author(s)
  土岐　力
- Organizer
  第57回日本小児血液・がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル、常磐ホテル（山梨県・甲府市）
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25461579
[Presentation] Gene alterations in Down syndrome-associated acute lymphoblastic leukemia in Japan2015
- Author(s)
  Terui K, Hanada I, Ikeda F, Ito T, Toki T, Kanezaki R, Sato T, Kamio T, Kudo K, Sasaki S, Takahashi Y, Hayashi Y, Inukai T, Hori H, Ito E
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂外（石川県・金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461560
[Presentation] Genetic basis of myeloid leukemogenesis in Down syndrome2013
- Author(s)
  Yoshida K, Toki T, Park M, Okuno Y, Shiraishi Y, Sanada M, Kon A, Nagata Y, Sato-Otsubo A, Sato Y, Wang R, Terui K, Kanezaki R, Shiba N, Chiba K, Tanaka H, Hama A, Muramatsu H, Hasegawa D, Nakamura K , Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kojima S, Izraeli S, Miyano S, Hayashi Y, Ito E, Ogawa S
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Genetic basis of myeloid leukemogenesis in Down syndrome.2013
- Author(s)
  Kenichi Yoshida, Tsutomu Toki, Myoung-ja Park, Yusuke Okuno , Yuichi Shiraishi, et al.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Identification of a novel causative gene, RPL27, in Diamond-Blackfan Anemia (Diamond-Blackfan貧血における新規原因遺伝子 RPL27の同定)2013
- Author(s)
  Wang R, Yoshida K, Okuno Y, Sato-Otsubo A, Toki T, Kudo K, Kanezaki R, Shiraishi Y, Chiba K, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kamimaki I, Hara J, Sugita K, Matsubara K, Koike K, Ishiguro A, Kawano Y, Kanno H, Kojima S, Sawada T, Uechi T, Kenmochi N, Miyano S, Ogawa S, Ito E
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Identification of two new DBA genes, RPS27 and RPL27, by Whole-Exome Sequencing in Diamond-Blackfan Anemia patients2012
- Author(s)
  Ito E, Yoshida K, Okuno Y, Sato-Otsubo A, Toki T, Miyano S, Shiraishi Y, Chiba K, Terui T, Wang R, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kudo K, Kamimaki I, Hara J, Sugita K, Matsubara K, Koike K, Ishiguro A, Kawano Y, Kanno H, Kojima S and Ogawa S
- Organizer
  第54回アメリカ血液学会
- Place of Presentation
  アトランタ
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Genetic basis of myeloid proliferation related to Down syndrome2012
- Author(s)
  Yoshida K, Toki T, Park MJ, Okuno Y, Shiraishi Y, Sanada M, Kon A, Nagata Y, Sato-Otsubo A, Sato Y, Wang RN, Terui K, Kanezaki R, Shiba N, Chiba K, Tanaka H, Hama A, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Miyano S, Kojima S, Izraeli S, Hayashi Y, Ito E, and Ogawa S.
- Organizer
  54th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  Atlanta, GA.
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] NOGマウスを用いたTAMの病態解析2012
- Author(s)
  才田聡,渡邉健一郎,佐藤亜以子,照井君典,吉田健一,奥野友介,土岐力,王汝南,白石友一,宮野悟,加藤格,森嶋達也,梅田雄嗣,平松英文,藤野寿典,足立壮一,丹羽明,中畑龍俊,伊藤悦朗,小川誠司,平家俊男
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] 小児科悪性腫瘍Down症候群に伴うTAM発症の分子機構2012
- Author(s)
  伊藤悦朗,金崎里香,王汝南,佐藤知彦,照井君典,土岐力
- Organizer
  第22回日本産婦人科・新生児血液学会学術集会
- Place of Presentation
  津市
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] Genetic Basis of Myeloid Proliferation Related to Down Syndrome2012
- Author(s)
  Yoshida K, Toki T, Ito E, Ogawa S et al.
- Organizer
  第54回アメリカ血液学会
- Place of Presentation
  米国・アトランタ
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Frequent mutations in the RPS17 gene in Japanese DBA Patients2012
- Author(s)
  Sato T, Kuramitsu M, Matsubara A, Yoshida K, Toki T, Terui K, Wang R, Kanno H, Morio T, Ohga S, Ohara A, Kitoh T, Kudo T, Kojima S, Ogawa S, Hamaguchi I, Ito E
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Quantitative or Qualitative Effect of mutant GATA1 factor on Phenotype of Transient Abnormal myelopoiesis2012
- Author(s)
  Toki T, Ito E
- Organizer
  第3回JSH国際シンポジウム
- Place of Presentation
  川越
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] 新生児科医のためのTAM診療ガイドラインTAM発症の分子機構2012
- Author(s)
  伊藤悦朗,金崎理香,王汝南,照井君典,土岐力
- Organizer
  第48回日本周産期・新生児医学会学術集会
- Place of Presentation
  大宮市
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] Novel GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down Syndrome2011
- Author(s)
  Tsutomu Toki, Eri Kobayashi, Rika Kanezaki, Runan Wang, Kiminori Terui, Hirokazu Kanegane, Miho Maeda, Takayoshi Koike, Mikiya Endo, Souichi Adachi, Yasuhide Hayashi, Ritsuko Shimizu, Masayuki Yamamoto, Etsuro Ito
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] GATA1 mutants lacking Rb-binding motif observed in transient abnormal myelopoiesis in Down syndrome2011
- Author(s)
  Tsutomu Toki
- Organizer
  53^<rd> American society of hematology annual meeting and exposition
- Place of Presentation
  San Diego Convention Center (San Diego, CA)
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] 先天性赤芽球.(Diamond-Blackfan貧血)の効果的診断法の確立関する研究2011
- Author(s)
  伊藤悦朗,照井君典,土岐力,小島勢二,小原明,大賀正一,森尾友宏,浜口功,倉光球,菅野仁,小川誠司,佐藤亜以子
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] Lower incidence of CRLF2 rearrangements in Down syndrome-associated acute lymphoblastic leukemia in Japan2011
- Author(s)
  Hanada I, Toki T, Ito E, 他12名
- Organizer
  全米血液学会
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] GATA1 mutants lacking Rb-binding motif observed in transient abnormal myelopoiesis in Down syndrome2011
- Author(s)
  Toki T, Ito E, 他12名
- Organizer
  全米血液学会
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] 小児ALLにおけるCRLF2、IKZF1、JAK2遺伝子の臨床的意義ダウン症候群関連ALLの発症におけるJAK2、およびCRLF2遺伝子異常の解析2011
- Author(s)
  花田勇,照井君典,土岐力,工藤耕,佐藤知彦,神尾卓哉,佐々木伸也,高橋良博,林泰秀,杉田完爾,小島勢二,小池健一,小阪嘉之,小林正夫,伊藤悦朗
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] ダウン症候群関連ALLにおけるJAK2およびCRLF2遺伝子異常の解析2011
- Author(s)
  花田勇、照井君典、土岐力、工藤耕、佐藤知彦、神尾卓哉、佐々木伸也、高橋良博、林泰秀、杉田完爾、小島勢二、小池健一、小阪嘉之、小林正夫、伊藤悦朗
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋市
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] JAK2 mutations and CRLF2 rearrangements in Down syndrome-associated acute lymphoblastic leukemia in Japan2011
- Author(s)
  Hanada I, Terui K, Toki T, Kudo K, Sato T, Kamio T, Sasaki S, Takahashi Y, Hayashi Y, Sugita K, Kojima S, Koike K, Kosaka Y, Kobayashi M, and Ito E.
- Organizer
  53th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] JAK2 mutations and CRLF2 rearrangements in Down syndrome-associated acute lymphoblastic leukemia in Japan.2011
- Author(s)
  Hanada I, Terui K, Toki T, Kudo K, Sato T, Kamio T, Sasaki S, Takahashi Y, Hayashi Y, Sugita K, Kojima S, Koike K, Kosaka Y, Kobayashi M, and Ito E.
- Organizer
  53rd American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] ダウン症候群に合併した一過性骨髄増殖症(TAM)および急性巨核芽球性白血病(AMKL)の全エクソンシーケンス2011
- Author(s)
  吉田健一,土岐力,朴明子,永田安伸,王汝南,白石友一,真田昌,昆彩菜,佐藤亜衣子,長崎正朗,宮野悟,金兼弘和,川上清,加藤剛二,小島勢二,林泰秀,伊藤悦朗,小川誠司
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] Novel GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome2011
- Author(s)
  Toki T, Kobayashi E, Kanezaki R, Wang RN, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adachi S, Hayashi Y, Shimizu R, Yamamoto M, and Ito E
- Organizer
  第73回日本血液学会学術集
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] GATA1 mutants lacking Rb-binding motif observed in transient abnormal myelopoiesis in Down syndrome2011
- Author(s)
  Tsutomu Toki, Eri Kobayashi, Rika Kanezaki, RuNan Wang, Kiminori Terui , Hirokazu Kanegane, Miho Maeda, Mikiya Endo, Tatsuki Mizuochi, Souichi Adachi, Yasuhide Hayashi, Ritsuko Shimizu, Masayuki Yamamoto, Etsuro Ito
- Organizer
  第53回米国血液学会
- Place of Presentation
  San Diego Convention Center, California
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] Extensive gene deletions in Japanese patients with Diamond.Blackfan anemia2011
- Author(s)
  Kuramitsu M, Matsubara A, Morio T, Takagi M, Toki T, Terui K, RuNan Wang, Kanno H, Ohga S, Ohara A, Kojima S, Kitoh T, Goi K, Kudo K, Matsubayashi T, Mizue N, Ozeki M, Masumi A, Momose H, Takizawa K, Mizukami T, Yamaguchi K, Ogawa S, ItoE, Hamaguchi I
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] ダウン症-過性異常骨髄増殖症にみられた新たな内部欠損変異GATA12011
- Author(s)
  土岐力
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] 先天性赤芽球瘻(Diamond-Blackfan貧血)の効果的診断法の確立関する研究2011
- Author(s)
  伊藤悦朗, 照井君典, 土岐力, 他8名
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-23390266
[Presentation] シンポジウム「TAMにみられたGATA1遺伝子異常の最近の話題」2011
- Author(s)
  土岐力
- Organizer
  第114回日本小児科学会学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] GATA1 mutants lacking Rb-binding motif observed in transient abnormal myelopoiesis in Down syndrome2011
- Author(s)
  Toki T, Kobayashi E, Kanezaki R, Wang RN, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adachi S, Hayashi Y, Shimizu R, Yamamoto M, and Ito E.
- Organizer
  53th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-23591527
[Presentation] Internal deletions of transcription factor GATA1 observed in transient abnormal myelopoiesis.2010
- Author(s)
  Toki T, Kanezaki R, Wang R, Terui K, Hayashi Y, Miura M, Maeda M, Ito E.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] Transient abnormal myelopoiesis and acute myeloid leukemia in Down syndrome(血液プレジデンシャルシンポジウム)2010
- Author(s)
  伊藤悦朗, 土岐力
- Organizer
  第52回日本小児血液学会総会
- Place of Presentation
  大阪国際会議場、大阪市
- Data Source
  KAKENHI-PROJECT-20390289
[Presentation] TAMの分子診断(シンポジウム:小児血液疾患の分子診断の進歩とその臨床応用)2010
- Author(s)
  伊藤悦朗、照井君典、土岐力
- Organizer
  第113回日本小児科学会学術集会
- Place of Presentation
  盛岡市
- Data Source
  KAKENHI-PROJECT-20390289
[Presentation] 典型例とは異なる緩徐な臨床経過を示し、リボソームタンパク遺伝子RPL11の変異の検出により診断したDiamond-Blackfan貧血の1例2010
- Author(s)
  佐野弘純,朴明子,外松学,今野友貴,土岐力,伊藤悦朗,林泰秀
- Organizer
  第52回日本小児血液学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] 小児血液疾患の分子診断の進歩とその臨床応用TAM発症の分子診断2010
- Author(s)
  伊藤悦朗,照井君典,佐藤知彦,土岐力
- Organizer
  第113回日本小児科学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder : mutation classes affect the phenotype of the disorder.2010
- Author(s)
  Etsuro Ito, Rika Kanezaki, Kiminori Terui, RuNan Wang, Tsutomu Toki
- Organizer
  5^<th> International Symposium on GATA factors (9^<th> Japanese Biochimical Society (JBS) Bio-Frontier Symposium 2010).
- Place of Presentation
  Gonryo-Hall, Sendai
- Data Source
  KAKENHI-PROJECT-20390289
[Presentation] ダウン症候群に発症する一過性骨髄異常増殖症(TAM)TAMにみられたGATA1遺伝子異常の最近の話題2010
- Author(s)
  土岐力,伊藤悦朗
- Organizer
  第52回日本小児血液学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] Internal deletions of transcription factor GATA1 observed in transient abnormal myelopoiesis2009
- Author(s)
  Tsutomu Toki, Rika Kanezaki, Ru Nan Wang , Kiminori Terui, Yasuhide Hayashi, Masayoshi Miura, Miho Maeda, Eturo Ito
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] GATA1、JAK3、JAK2変異を有するダウン症関連急性巨核芽球性白血病由来細胞株(CHYNA)の樹立2009
- Author(s)
  濱麻人,松本公一,土岐力,村松秀城,西尾信博,永田俊人,高橋義行,伊藤悦朗,小島勢二
- Organizer
  第51回日本小児血液学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] Mutations in ribosomal protein genes of Diamond-Blackfan anemia patients in Japan.2009
- Author(s)
  Konno Y, Toki T, Tandai S, Xu G, Terui K, Ohga S, Kojima S, Yanagisawa R, Koike K, Hasegawa D, Kosaka Y, Kanei R, Imai T, Hongo T, Park MJ, Watanabe A, Ito E
- Organizer
  51st American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] 小児血液腫瘍の発症リスクと先天異常ダウン症候群と血液腫瘍2009
- Author(s)
  土岐力,伊藤悦朗
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] 新規KIT選択的阻害剤KI-328の抗白血病細胞効果の検討2009
- Author(s)
  辻村朱音,塩津行正,清井仁,石川裕一,森裕美子,石田広志,新美圭子,土岐力,伊藤悦朗,直江知樹
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] ダウン症候群と血液腫瘍2009
- Author(s)
  土岐力
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] 本邦のDiamond-Blackfan貧血患者におけるリボゾームタンパク遺伝子の変異2009
- Author(s)
  今野友貴,丹代諭,徐剛,土岐力,工藤耕,照井君典,大賀正一,小島勢二,長谷川大一郎,青木由貴,金井理恵,今井剛,本郷輝明,朴明子,柳沢龍,伊藤悦朗
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] 小児科領域の血液疾患一過性骨髄増殖性疾患2009
- Author(s)
  伊藤悦朗,土岐力,金崎里香,佐藤知彦,照井君典,足立壮一
- Organizer
  第10回日本検査血液学会
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] シンポジウム「ダウン症候群と血液腫瘍」2009
- Author(s)
  土岐力
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-21591344
[Presentation] ダウン症候群と血液腫瘍2009
- Author(s)
  土岐力
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都市
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] Activating JAK3 Mutations in Transient Myeloproliferative Disorder and Acute Megakaryoblastic Leukemia Accompanying Down Syndrome.2008
- Author(s)
  Toki T, Ito E, et. al.
- Organizer
  The 50th Mnnual meeting of American Society of Hematology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-17013004
[Presentation] ダウン症関連白血病細胞の増殖におけるStem cell factor/KITシグナリング2008
- Author(s)
  土岐力,金崎里香,足立壮一,徐剛,佐藤知彦,鈴木か, ほり,田内久道,遠藤幹也,伊藤悦朗
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] t(1;16;8)を有する新生児AMLの自然寛解例で認められたMOZ-CBP融合遺伝子の新規variant2008
- Author(s)
  照井君典,佐藤知彦,神尾卓哉,工藤耕,佐々木伸也,土岐力,高橋良博,菊地陽,伊藤悦朗
- Organizer
  第50回日本小児血液学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] The Essential Role of Stem Cell Factor/KIT Signaling in the Proliferation and Survival of Blast Cells from Transient Leukemia in Neonates with Down Syndrome2008
- Author(s)
  Tsutomu TOKI
- Organizer
  50^<th> American Society of Hematology Ann ual Meeting
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19591236
[Presentation] Activating JAK3 Mutations in Transient Myeloprolifetative Disorder and Acute Megalcaryoblastic Leukemia Accompanying Down Syndrome2008
- Author(s)
  Toki T, Ito E, et.al.
- Organizer
  The 50^<th> Mnnual meeting of American Society of HematologY
- Place of Presentation
  サンフランシスコ(米国)
- Year and Date
  2008-12-08
- Data Source
  KAKENHI-PROJECT-20390289
[Presentation] The Essential Role of Stem Cell Factor/KIT Signaling in the Proliferation and Survival of Blast Cells from Transient Leukemia in Neonates Tith Down Syndrome2008
- Author(s)
  Tsutomu TOKI
- Organizer
  50^<th> American Society of Hematology Annual Meeting
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19591236
[Presentation] ダウン症関連白血病およびTMDにおけるJAK3遺伝子変異の機能解析2008
- Author(s)
  佐藤知彦,土岐力,金崎里香,徐剛,照井君典,金兼弘和,三浦正義,足立壮一,右田昌宏,森永信吾,中野崇秀,遠藤幹也,小島勢二,清井仁,間野博行,伊藤悦朗
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591241
[Presentation] 一過性骨髄増殖症のマイナークローンから発生したダウン症関連急性巨核球性白血病2007
- Author(s)
  土岐力
- Organizer
  第69回日本血液学会第49回日本臨床血液学会合同総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19591236
[Presentation] Activating JAK3 Mutations in Transient Myeloproliferative Disorder and Acute Megakaryoblastic Leukemia Accompanying Down Syndrome.2007
- Author(s)
  Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kamio T, Kojima S, Kiyoi H, Mano H, Ito E.
- Organizer
  The 49^<th> ASH meeting
- Place of Presentation
  Atlanta, Georgia
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] Molecular mechanisms of TAM development2007
- Author(s)
  Ito E, Xu G, Kanezaki R, Toki T.
- Organizer
  The 17^<th> Annual meeting of Japanese Society for Obstetrics and Gynecology, and Pediatric Hematology
- Place of Presentation
  Toyama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] Activating JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome.2007
- Author(s)
  Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kamio T, Kiyoi H, Mano H, Ito E.
- Organizer
  The 49th Mnnual meeting of American Society of Hematology
- Place of Presentation
  アトランタ
- Data Source
  KAKENHI-PROJECT-17013004
[Presentation] Activating JAK3 Mutations in Transient Myeloproliferative Disorder and Acute Megakaryoblastic Leukemia Accompanying Down Syndrome2007
- Author(s)
  Sato T, Toki T. Ito E, et. al.
- Organizer
  The 49th Mnnual meeting of American Society of Hematology
- Place of Presentation
  アトランタ(米国)
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] 一過性骨随増殖症のマイナークローンから発生したダウン症関連急性巨核球性白血病2007
- Author(s)
  土岐力
- Organizer
  第69回日本血液学会第49回日本臨床血液学会合同総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19591236
[Presentation] Activating JAK3 Mutations in Transient Myeloproliferative Disorder and Acute Megakaryoblastic Leukemia Accompanying Down Syndrome2007
- Author(s)
  Sato T, Toki T, Kanezaki R, Xu G, Ito E, ed. al.
- Organizer
  The 49^<th> ASH meeting, December 8-11
- Place of Presentation
  Atlanta, Georgia, USA.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] Activating JAK3 Mutations in Transient Myeloproliferative Disorder and Acute Megakaryoblastic Leukemia Accompanying Down Syndrome2007
- Author(s)
  Sato T, Toki T, Ito E, et. al.
- Organizer
  The 49th Mnnual meeting of American Society of Hematology
- Place of Presentation
  アトランタ(米国)
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-17013004
[Presentation] TAM発症の分子機構 (シンポジウム)2007
- Author(s)
  伊藤悦朗、徐剛、金崎理香、土岐力
- Organizer
  第17回日本産婦人科・新生児血液学会
- Place of Presentation
  富山市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] Molecular mechanisms of TAM development2006
- Author(s)
  Ito E, Xu G, Kanezaki R, Terui K, Toki T.
- Organizer
  The 51th Annual Meeting of Japan Society for Premature and Newborn Medicine
- Place of Presentation
  Saitama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] TAM発症の分子機構(シンポジウム).2006
- Author(s)
  伊藤悦朗、徐剛、金崎理香、照井君典、土岐力
- Organizer
  第51回日本未熟児新生児学会
- Place of Presentation
  さいたま市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390295
[Presentation] In-frame deletion of GATA1 in pediatric acute megakaryoblastic leukemia without Down syndrome.
- Author(s)
  金崎里香, 王汝南, 土岐力, 照井君典, 佐々木伸也, 工藤耕, 神尾卓哉, 池田史圭, 伊藤悦朗
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461559

1. ITO Etsuro (20168339)

# of Collaborated Projects: 28 results

# of Collaborated Products: 131 results
2. TERUI Kiminori (00333740)

# of Collaborated Projects: 12 results

# of Collaborated Products: 67 results
3. KANEZAKI RIKA (60722882)

# of Collaborated Projects: 9 results

# of Collaborated Products: 10 results
4. Kudo Ko (20455728)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
5. Sato Tomohiko (70587005)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. WATANABE Seiji (10241449)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. YOKOYAMA Masaru (60003480)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAKAHASHI Yoshihiro (10333725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. KAMIO TAKUYA (50587011)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 佐々木伸也 (10344590)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ARAI Koji (40232011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 吉村教あき (60018893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 杉山一夫 (00006719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 畠山幸紀 (80241454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 種田晃人 (70332492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Dario Campana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 北澤淳一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ITO Ryoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. PARK Myoung-Ja

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. KITABATAKE Yasuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
22. 江藤浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 佐藤悠佑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 大賀正一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 菅野仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 落合博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 松尾英将

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 林泰秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
29. 中畑龍俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 伊藤守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 上地珠代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 清水律子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 西中瑶子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 野津寛大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Toki Tsutomu 土岐 力

TOKI Tsutomu 土岐 力

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ダウン症関連白血病における転写因子GATA1スプライシング異常の影響と作用機構Principal Investigator

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Functional analysis of the tandem duplication mutation RUNX1 in leukemogenesisPrincipal Investigator

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Elucidation of the pathogenesis of diamond-blackfan anemia and identification of novel therapeutic targetsPrincipal Investigator

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Toki Tsutomu 土岐力

TOKI Tsutomu 土岐力