Saito Shinji 斎藤慎二

… Alternative Names

Researcher Number	50195989
Other IDs
Affiliation (Current)	2021: 常磐大学, 人間科学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2019: 常磐大学, 人間科学部, 教授 2017: 筑波大学, 医学医療系, 准教授 2015: 筑波大学, 医学医療系, 准教授 2013: 筑波大学, 医学医療系, 准教授 2001 – 2006: 自治医科大学, 医学部, 助手 1991 – 1998: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Otorhinolaryngology Except Principal Investigator 細菌学 / Bacteriology (including Mycology) / Pediatrics / Pediatrics / Bacteriology (including Mycology)
Keywords	Principal Investigator マクロファージ / LPS / LSP / CD14 / NO / 鼻腔上皮細胞 / IL-12 / MAPK / ERK / サイトカイン … More Except Principal Investigator エンドトキシン / Microcystin / TSS / TSST-1 / NTED / MRSA / 腫瘍壊死因子(TNF) / Microcystis aeruginosa / エンドトキシンショック / エンドトキシントレランス / 合成リピドA類縁化合物 / リポ多糖(LPS) / 細菌感染 / 細菌リポ多糖(LPS) / マクロファージ / 蛋白リン酸化 / サルモネラ / インターロイキン6 / gamma-linolenic acid / 腫瘍壊死因子 / Interleukin-6 / リボ多糖 / リポ多糖 / LPS / TNF / IL-6 / Endotoxin / IL-12 / IL-18 / スーパー抗原 / 新生児TSS様発疹症 / 川崎病 / superantigen / Kawasaki disease / リポポリサッカライド / 細菌内毒素 / プラスチン / レジオネラ / モノカイン / 緑膿菌 / マクロファ-ジ / Lーアルギニン / Bacterial Infection / Bacterial Lipopolysaccharide (LPS) / Macrophages / Protein Phosphorylation / Plastin / Legionella / Salmonella / Monokine / シアノバクテリア / ミクロシスチン / 抗菌活性物質 / 培養法 / モノクローナル抗体 / γ-linolenic acid / ミクロキスチス / 凍結保存法 / ミクロキスチン / Cyanobacteria / antibacterial substance / culture method / monoclonal antibody / インターロイキン10 / 活性酸化窒素 / モノクロナール抗体 / Microcystis / microcystin / インターロイキン 6 / インターロイキン 10 / microcystis / Interleukin-10 / Monoclonal antibody / BACTERIAL INFECTION / PROTEIN PHOSPHORYLATION / SALMONELLA / ENDOTOXIN / LIPOPOLYSACCHARIDE / MACROPHAGE / リピドA / ヒトマクロファージ / TNF-α / Lipopolysaccharide / Lipid A / Human macrophages / 細菌リポ多糖 / インターフェロン-γ / 一酸化窒素 / Lipopolysaccharidc / Interferon-γ / Nitric oxide / 新生児 / neonatal TSS-like exanthematous disease / neonates / サイトカイン / cytokine / 内毒素 / IL-12発現調節 / LPSアンタゴニスト / lipopolysaccharide (LPS) / endotoxin / regulation of IL-12 expression / LPS antagonist Less

The construction of the human nasal epithelium environment model and search of novel allergic regulationPrincipal InvestigatorOngoing
- Principal Investigator
  
  斎藤慎二
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tokiwa University
  University of Tsukuba
The pathophysiologic influence of Staphylococcus aureus and other flora on allergic rhinitis.Principal Investigator
- Principal Investigator
  
  Saito Shinji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Tsukuba
Mechanisms for regulation of excessive host responses to LPS
- Principal Investigator
  
  MATSUURA Motohiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University
Immunological investigation for pathophysiology of infectious diseases induced by bacterial superantigens in neonates and childhood
- Principal Investigator
  
  TAKAHASHI Naoto
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Pathopysiological aspects of Neonatal TSS-like exanthematous disease and Kawasaki disease
- Principal Investigator
  
  TAKAHASHI Naoto
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  JICHI MEDICAL SCHOOL
Endogenous interferon-γ induced by bacterial lipopolysaccbaride ; its production mechanism and roles as a mediator
- Principal Investigator
  
  MATSUURA Motohiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical School
Elucidation of signaling molecules involved in macrophage activation by bacterial lipopolysaccharidePrincipal Investigator
- Principal Investigator
  
  SAITO Shinji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical School
Studies on regulatory mechanisms of LPS signal transductions in human cells.
- Principal Investigator
  
  MATSUURA Motohiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical School
細菌感染,細菌内毒素によるマクロファージ活性化に関与するシグナル伝達分子の解析Principal Investigator
- Principal Investigator
  
  斎藤慎二
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University
細菌感染,細菌内毒素によるマクロファージ活性化における分子機序の解析Principal Investigator
- Principal Investigator
  
  斉藤慎二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University
細菌感染,細菌内毒素によるマクロファージ活性化における分子機序の解析Principal Investigator
- Principal Investigator
  
  斎藤慎二
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University
エンドトキシンショックの抑制機構に関する分子生物学的研究
- Principal Investigator
  
  松浦基博
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University
マクロファージの刺激応答および活性化における分子機序の解析Principal Investigator
- Principal Investigator
  
  斎藤慎二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University
Analysis of specific protein phosphorylation after infection with bacteria
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical School
内毒素の素性に対するトレランス誘導機構の分子生物学的研究
- Principal Investigator
  
  MATSUURA Motohiro
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical University
Toxic action of Mycrocystis, a causative bacteria for water pollution
- Principal Investigator
  
  NAKANO Yasunobu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School
Molecular biology on murine macrophage activated by bacterial infection or bacterial components
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School
Gross culture system for cyanobacteria & its application for medication
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School

All 2018 2017 2015 2006 2005

All Journal Article

[Journal Article] Antioxidative Nanoparticles Significantly Enhance Therapeutic Efficacy of an Antibacterial Therapy against Listeria monocytogenes Infection2018
- Author(s)
  Ikeda Yutaka、Shoji Kazuhiro、Feliciano Chitho P.、Saito Shinji、Nagasaki Yukio
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Pages: 1126-1132
- DOI
  10.1021/acs.molpharmaceut.7b00995
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11352, KAKENHI-PROJECT-18H04160
[Journal Article] Sodium Polyanethol Sulfonate Modulates Natural Transformation of SigH-Expressing Staphylococcus aureus2017
- Author(s)
  Nguyen Le Thuy Thi、Takemura Aya J.、Ohniwa Ryosuke L.、Saito Shinji、Morikawa Kazuya
- Journal Title
  
  Current Microbiology
  
  Volume: 75 Pages: 499-504
- DOI
  10.1007/s00284-017-1409-5
- NAID
  120006463924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11352
[Journal Article] Staphylococcus aureus dry stress survivors have a heritable fitness advantage in subsequent dry exposure2015
- Author(s)
  Maudsdotter L, Imai S, Ohniwa RS, Saito S, and Morikawa K
- Journal Title
  
  Microbes and Infection
  
  Volume: 17 Pages: 456-461
- DOI
  10.1016/j.micinf.2015.02.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462659, KAKENHI-PROJECT-25840002
[Journal Article] Regulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK pathway2006
- Author(s)
  S.Saito, et al.
- Journal Title
  
  Clin.Vaccine Immunol. 13-8
  
  Pages: 876-883
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590397
[Journal Article] Regulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK patway2006
- Author(s)
  S.Saito
- Journal Title
  
  Clin. Vaccine Immunol. 13・8
  
  Pages: 876-883
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590397
[Journal Article] Regulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK pathway2006
- Author(s)
  S.Saito
- Journal Title
  
  Clin. Vaccine Immunol. 13・8
  
  Pages: 876-883
- Data Source
  KAKENHI-PROJECT-17590397
[Journal Article] Hyperactivation of the ERK pathway plays a role in suppressive mechanisms of LPS-induced IL-12p40 production2005
- Author(s)
  S.Saito, et al.
- Journal Title
  
  Proceedings of Toxin Symposium 52
  
  Pages: 140-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590397
[Journal Article] ERK1/2経路の過剰活性化によるLPS誘導IL-12p40の抑制調節機構2005
- Author(s)
  斎藤慎二, 松浦基博, 平井義一
- Journal Title
  
  第52回毒素シンポジウム予稿集(ISSN-1334-934) 52
  
  Pages: 140-145
- Data Source
  KAKENHI-PROJECT-17590397
[Journal Article] ERK1/2経路の過剰活性化によるLPS誘導IL-12p40の抑制調節機構2005
- Author(s)
  斎藤慎二
- Journal Title
  
  第52回毒素シンポジウム予稿集 (ISSN-1344-934) 52
  
  Pages: 140-145
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590397

1. MATSUURA Motohiro (20150089)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. NAKANO Masayasu (70048958)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. GUNJI Yuuji (90245043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KIRIKAE Teruo (50192563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKANO Yasunobu (70207851)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKAHASHI Naoto (50197159)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HONMA Youko (10238826)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YADA Yukari (00296089)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. OHNIWA Ryosuke (30447883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. YOKOTA Shinichi (10325863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIRAI Makoto (10007792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKI Tatuo (70049097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIRAIASHI Hirohiko (40187521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KIKUCHI Ken (60214748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 渋谷泰寛 (20187420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YANASE Haruka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 長崎幸夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Shinji 斎藤 慎二

斎藤 慎二 サイトウ シンジ

SAITOH Shinji 斎藤 慎二

SAITOH Sinji 齋藤 慎二

SAITO Shinji 斎藤 慎二

Research Projects

Research Products

Co-Researchers

The construction of the human nasal epithelium environment model and search of novel allergic regulationPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathophysiologic influence of Staphylococcus aureus and other flora on allergic rhinitis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of signaling molecules involved in macrophage activation by bacterial lipopolysaccharidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細菌感染,細菌内毒素によるマクロファージ活性化に関与するシグナル伝達分子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細菌感染,細菌内毒素によるマクロファージ活性化における分子機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細菌感染,細菌内毒素によるマクロファージ活性化における分子機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マクロファージの刺激応答および活性化における分子機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Saito Shinji 斎藤慎二

斎藤慎二サイトウシンジ

SAITOH Shinji 斎藤慎二

SAITOH Sinji 齋藤慎二

SAITO Shinji 斎藤慎二