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NAKASHIMA manabu  中島 学

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中島 学  ナカシマ マナブ

NAKASHIMA Manabu  中島 学

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Researcher Number 50198074
Other IDs
Affiliation (Current) 2025: 独立行政法人国立病院機構福岡東医療センター(臨床研究部), 独立行政法人国立病院機構福岡東医療センター臨床研究部, 医師
Affiliation (based on the past Project Information) *help 2009 – 2014: Fukuoka University, 薬学部, 教授
2007: 福岡大学, 医学部, 教授
2007: Fukuoka University, Faculty of Pharmaceutical Sciences, Department of Clinical Pharmacology, Professor
2006: 福岡大学, 医学部, 助教授
2004: 福岡大学, 薬学部, 助教授
1997 – 2003: 九州大学, 生体防御医学研究所, 助手
1991 – 1993: 九州大学, 生体防御医学研究所, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Immunology / Laboratory medicine
Except Principal Investigator
Obstetrics and gynecology / Hematology / Immunology
Keywords
Principal Investigator
RCAS1 / 免疫学 / 膵液 / 抗体 / 癌 / cytokine production / gene targeting / B cells / Th2 cells / Th1 cell … More / signal transduction / antigen receptor / G protein coupled receptor / Th2バランス / TH1 / Gタンパク結合型受容体(GPCR) / ZAP-7 / Btk / ヒスタミンHI受容体欠損マウス / サイトカイン産生 / ジーンターゲティング / B細胞 / Th2細胞 / Th1細胞 / シグナル伝達 / 抗原受容体 / Gタンパク結合型受容体 / gene expression / Transgenic mouse / silencer / enhancer / Immunoglobulin gene / 転写調節 / サイレンサ- / イントロン・エンハンサ- / 遺伝子発現調節 / トランスジェニックマウス / サイレンサー / エンハンサー / 免疫グロブリン遺伝子 / 単クローン抗体 / 腫瘍検査学 / シアリル化ルイス a 抗原 / Tn 抗原 / 膵癌 / 単クローナル抗体 / 癌マーカー / 診断 / 臨床 / Cell cycle arrest / Tyrosine Phosphorylation / Signal pathway / K562 / receptor / 細胞周期 / シグナル / 細胞死(Apoptosis) / 腫瘍関連抗原 / II型膜タンパク / モノクローナル抗体 / 癌の浸潤・転移 / 細胞増殖 / アポトーシス / 22-1-1抗体 / 腫瘍免疫 … More
Except Principal Investigator
RCAS1 / アポトーシス / siRNA / ectodomain shedding / ELISA / apoptosis / Akt / Ly49 / 腫瘍免疫 / 癌浸潤 / ヒト癌抗原 / 癌免疫療法 / サイトカイン / tareeting therapy / tumorigenesis / tumor stromal tissue / lymphocyte apoptosis / bioactive marker / 細胞内シグナル伝達機構 / 婦人科癌 / 治療標的分子 / 造腫瘍性 / 腫瘍間質組織 / リンパ球アポトーシス / progenitors / erythroid / macrophages / macrophage / hematopoiesis / サラセミア / 赤血球 / マクロファージ / 赤芽球系前駆細胞 / phosphataseu / Negative regulation / tyrosine phosphorylation / autoantibody / gene targeting / Lyn kinase / Golgi膜 / PITPnm / 2 / SHP1 / 抗原受容体シグナル / B1細胞 / 自己免疫性貧血 / トランスジェニックマウス / フォスファターゼ / 負の制御 / チロシンリン酸化 / 自己抗体産生 / ジーンターゲンティング / Lynキナーゼ / RCAS1受容体 / 細胞増殖抑制 / 免疫病からのエスケープ / RCASI受容体 / RCASI / II型膜タンパク / モノクロナール抗体 / 癌マーカー / 細胞死 / リンパ球 / 受容体 / cDNAクローニング / 腫瘍関連抗原 / 癌抗原ペプチド / 自家腫瘍特異的CTL / メラノーマ / 抗原ペプチド / ヒトヘルパーT細胞 / ヒトT細胞長期培養 / ヒトCTL / 腫瘍特異抗原 Less
  • Research Projects

    (16 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (13 People)
  •  Research of established monoclonal antibodies against tumor related molecules in a pancreatic juicePrincipal Investigator

    • Principal Investigator
      NAKASHIMA manabu
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Fukuoka University
  •  癌性膵液を用いたサブトラクティブ免疫法による新規単クローン抗体の作製と応用Principal Investigator

    • Principal Investigator
      中島 学
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Fukuoka University
  •  Manufacture of novel RCAS1-targeting therapy against gynecologic cancer

    • Principal Investigator
      SONODA Kenzo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kyushu University
  •  RCAS1抗原に対する生体反応の検出とその臨床的意義の検討Principal Investigator

    • Principal Investigator
      中島 学
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Fukuoka University
  •  癌の免疫学的監視機構からの逸脱におけるRCAS1分子の意義Principal Investigator

    • Principal Investigator
      中島 学
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Study on regulatory mechanism of hematopoiesis by RCAS-1 ; Application in hematopoietic stem cell transplantation.

    • Principal Investigator
      MUTA Koichiro
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyushu University
  •  ヒト癌抗原RCAS1による細胞周期停止の機構とその受容体の構造の解析Principal Investigator

    • Principal Investigator
      中島 学
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  免疫細胞に細胞死を誘導するヒト癌抗原RCAS1分子とその受容体の機能の解析Principal Investigator

    • Principal Investigator
      中島 学
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  細胞死誘導活性を示すヒト癌抗原分子とその受容体の機能

    • Principal Investigator
      渡邊 武
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  Regulatory mechanism on B cell antigen receptor-mediated signal transduction and gene expression.

    • Principal Investigator
      WATANABE Takeshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  Role of G protein coupled receptor (GPCR)-mediated signals in the activation of immune cell.Principal Investigator

    • Principal Investigator
      NAKASHIMA Manabu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  細胞死誘導活性を示すヒト癌抗原分子(RCASI)とそのリガンドの機能解析

    • Principal Investigator
      渡邊 武
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  接着因子活性を有する新しい腫瘍関連抗原分子の機能解析

    • Principal Investigator
      渡邊 武
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  免疫ネットワークを用いたヒト癌免疫療法の開発と応用

    • Principal Investigator
      渡辺 武
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  免疫細胞ネットワークを用いたヒト癌免疫療法の開発

    • Principal Investigator
      WATANABE Takeshi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  Identification of Transcriptional Factor(s) which regulates Ig gene expressionPrincipal Investigator

    • Principal Investigator
      NAKASHIMA Manabu
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      KYUSYU UNIVERSITY

All 2012 2011

All Journal Article Presentation

  • [Journal Article] The utility of a novel antibody in the pathological diagnosis of pancreatic acinar cell carcinoma2012

    • Author(s)
      M Yasumoto,M Hamabashiri,J Akiba,S Ogasawara,Y Naito,T Taira,M Nakayama,A Daicho,F Yamasaki,K Shimamatsu,Y Ishida,R Kaji,Y Okabe,O Nakashima,K Ohshima,M Nakashima,M Sata,H Yano
    • Journal Title

      J Clin Pathol.

      Volume: 65 Pages: 327-332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590698
  • [Journal Article] Novel monoclonal antibodies against pancreatic juice from pancreatic cancer patients and their possible application in differential diagnosis.2011

    • Author(s)
      Masato Hamabashiri, Aya Daichou, Makiko Yasumoto, Sachiko Ogasawara,Takuya Nishinakagawa, Munechika Enjoji, Kouichi Ohshima, Hirohisa Yano and Manabu Nakashima
    • Journal Title

      Int J Mol Med.

      Volume: 28 Pages: 599-603

    • NAID

      110009552409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590698
  • [Presentation] Tn抗原に対する新規モノクローナル抗体6P-3-2-4と22-1-1との反応性の比較2012

    • Author(s)
      濱走優人、桑水流裕太、安元真希子、秋葉 純、小笠原幸子、西中川拓也、矢野博久、中島 学
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌(北海道大学)
    • Data Source
      KAKENHI-PROJECT-23590698
  • [Presentation] A novel monoclonal antibody against Tn antigen and comparison of reactivity with 22-1-12011

    • Author(s)
      M. Hamabashiri, M. Yasumoto, T. Nishinakagawa, S. Ogasawara, M. Enjoji, K. Ohshima,H. Yano, M. Nakashima
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Data Source
      KAKENHI-PROJECT-23590698
  • 1.  WATANABE Takeshi (40028684)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  KITAMURA Daisuke (70204914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  MUTA Koichiro (50229928)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ABE Yasunobu (90304774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SONODA Kenzo (30294929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MIYAMOTO Shingo (40209945)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  高橋 三津雄 (70299543)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YANO Hirohisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 9.  OHSHIMA Kouichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 10.  YASUMOTO Makiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  NISHINAKAGAWA Takuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  HAMABASHIRI Masato
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  DAICHO Aya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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