FUJIMURA Takao 藤村響男

… Alternative Names

藤村響男フジムラタカオ

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Researcher Number	50209087
Other IDs
External Links
Affiliation (Current)	2025: ヤマザキ動物看護専門職短期大学, 動物トータルケア学科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: ヤマザキ動物看護専門職短期大学, 動物トータルケア学科, 教授 2019 – 2022: 北里大学, 医学部, 講師 2011 – 2015: 北里大学, 医学部, 講師 2003 – 2006: 北里大学, 医学部, 講師 1994 – 1995: Kitasato Univ. Sch. of Med. Assistant, 医学部, 助手 1988: 新潟大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related / Dermatology Except Principal Investigator Dermatology / Basic Section 58080:Gerontological nursing and community health nursing-related / 細菌学 / Dermatology / Eating habits, studies on eating habits
Keywords	Principal Investigator 侵入蛋白 / AIDA / 感染様式 / ワクチン / らい菌 / ハンセン病 / Virulence factor / Mammalian cell entry / mce1A gene / Mycobacterium leprae … More / mce / 病原因子 / 高度免疫血清 / 抗mce抗体 / 感染防御ワクチン / らい菌侵入抑制 / mce蛋白 / 抗mec抗体 / 遅延型過敏反応 / インターロイキン10 / インターフェロンγ / 細胞性免疫 / 免疫応答 / 慢性粘膜皮膚カンジダ症 … More Except Principal Investigator LAK / rIL-2 / 皮膚バリア / 細菌 / 殺菌 / 手指衛生 / 抗ウイルス活性 / 抗真菌活性 / 抗菌活性 / 看護師 / 手湿疹 / スキンバリア / 角層水分量 / 抗菌 / TEWL / 噴霧型 / オゾン水 / T cell / Macrophages / IL-1 (Interleukin-1) / Hemolysin / Intracellular bacteria / Listeria monocytogenes / 感染抵抗性T細胞 / 遅延型過敏反応 / 感染防御免疫 / リステリア菌 / 細胞性免疫 / T細胞 / マクロファ-ジ / IL-1(インタ-ロイキン-1) / ヘモリシン / 細胞内寄生性細菌 / リステリア / adoptive immunotherapy / killer cells / helper / bispecific antibody / Malignant hemangioendo-thwlioma / キラー / ペルパー / 悪性血管内皮細胞 / 養子免疫療法 / キラー細胞 / ヘルパー / バイスペシフィック抗体 / 悪性血管内皮細胞腫 / 細胞侵入因子 / 遅発育性抗酸菌 / mce1A遺伝子 / 細胞内侵入 / 病原因子 / 細胞内侵入因子 / mce遺伝子 / ハンセン病 / らい菌 / リガンド / ナチュラルリガンド / インバリアントNKT細胞 / 構造 / スフィンゴ糖脂質 / 米糠 / Rice bran / Sphingoglycolipid / Natural ligand / Invariant NKT cell / Thai53株 / ヒト血管肉腫 / 超低増殖細胞 / 16S rRNA primer / 28℃ / SLG細胞 / ライ菌 Less

ハンセン病の感染様式に関る分子機構の解明とそれを標的とした感染防御ワクチンの開発Principal Investigator
- Principal Investigator
  
  藤村響男
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  ヤマザキ動物看護専門職短期大学
   Kitasato University
Medical applications of portable ozone water device for both maintenance of skin barrier function and hand hyagene in hospital-based nurses
- Principal Investigator
  
  NAKANO Toshiaki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  St. Luke's International University
Development of Vaccine for Hansen's Disease-Targeting the M.leprae Molecular Mechanism for Entry into Nasal Mucosal Epithelial CellsPrincipal Investigator
- Principal Investigator
  
  Fujimura Takao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Kitasato University
Development of gene replacement system in slow growth mycobacteria to express green fluorescent protein and knock out the mce1A gene in recombinant strains of Mycobacterium leprae
- Principal Investigator
  
  SATO NAOYA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Kitasato University
Identification of natural ligand for invariant NKT cells
- Principal Investigator
  
  EMOTO Masashi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Gunma University
内皮系超低増殖細胞によるライ菌の長期体外培養法の樹立
- Principal Investigator
  
  増澤真実子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Kitasato University
Recombinant expression and functional analysis of the protein encoded by Mce 1A region of Mycobacterium leoraePrincipal Investigator
- Principal Investigator
  
  FUJIMURA Takao
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kitasato University
表在性カンジダ症と慢性粘膜皮膚カンジダ症に於けるサイトカイン及びNO産生能の比較Principal Investigator
- Principal Investigator
  
  藤村響男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Dermatology
- Research Institution
  Kitasato University
Basic study of anti-CD3 X anti-tumor bispecific antibody therapy using helper/killer cells for malignant hemangioentothelioma.
- Principal Investigator
  
  MASUZAWA Mikio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kitasato University School of Medicine
Analysis of virulence factor and the mechanisms for induction of cell-mediated immunity by intracellular bacterium, Listeria monocytogenes.
- Principal Investigator
  
  MITSUYAMA Masao
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Niigata University School of Medicine

All 2016 2013 2011 2007 2006 Other

All Journal Article Presentation Patent

[Journal Article] Recombinant Mycobacterium leprae protein associated with entry into mammalian cell of respiratory and skin components2007
- Author(s)
  Naoya Sato, Takao Fujimura, et. al.
- Journal Title
  
  Journal of Dermatological Science 46
  
  Pages: 101-110
- NAID
  10024116033
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591190
[Journal Article] Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin components2007
- Author(s)
  Naoya Sato, Takao Fujimura, et al.
- Journal Title
  
  Journal of Dermatological Science online
  
  Pages: 10-10
- NAID
  10024116033
- Data Source
  KAKENHI-PROJECT-15591190
[Journal Article] Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin components.2007
- Author(s)
  Naoya Sato, Takao Fujimura, Mikio Masuzawa, Yasuko Yogi, Masanori Matsuoka, Maha Kanoh, Lee W. Riley, Kensei Katsuoka
- Journal Title
  
  Journal of Dermatological Science(Epub) 46(2)
  
  Pages: 101-10
- NAID
  10024116033
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591190
[Journal Article] らい菌mce1A遺伝子にコードされる蛋白はヒト上皮細胞への侵入に関与する重要な病原因子である2006
- Author(s)
  佐藤直哉, 藤村響男, ら
- Journal Title
  
  北里医学 36
  
  Pages: 65-73
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591190
[Journal Article] らい菌mce1A遺伝子にコードされる蛋白はヒト上皮細胞への侵入に関与する重要な病原因子である2006
- Author(s)
  佐藤直哉, 藤村響男 et al.
- Journal Title
  
  北里医学 36
  
  Pages: 65-73
- Data Source
  KAKENHI-PROJECT-15591190
[Journal Article] Mycobacterium leprae protein encoded by the mcelA gene is an important virulence factor associated with mammalian epithelial cell entry.2006
- Author(s)
  Naoya Sato, Takao Fujimura, Yasuko Yogi, Maho Kanoh, Mikio Masuzawa, Kensei Katsuoka
- Journal Title
  
  Kitasato Medicine 36
  
  Pages: 65-73
- NAID
  110006405960
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591190
[Patent] 細胞内に侵入する能力を有するペプチド及び核酸、物質を細胞内に侵入させるための物質移送用剤及び物質移送方法、並びに、らい菌による感染症を予防又は治療するためのワクチン、抗体及び医薬2006
- Inventor(s)
  藤村, 響男
- Industrial Property Rights Holder
  北里学園
- Industrial Property Number
  2006-347090
- Filing Date
  2006-12-25
- Data Source
  KAKENHI-PROJECT-15591190
[Patent] 細胞内に侵入する能力を有するペプチド及び核酸, 物質を細胞内に侵入させるための物質移送用剤及び物質移送方法, 並びに, らい菌による感染症を予防又は治療するためのワクチン, 抗体及び医薬2006
- Inventor(s)
  藤村響男
- Industrial Property Rights Holder
  北里学園
- Industrial Property Number
  2006-347090
- Filing Date
  2006-12-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591190
[Presentation] Unique regions in the Mycobacterium leprae Mce1A protein associated with the initial transmission of leprosy2016
- Author(s)
  Viesta baby Fadlitha, Naoya Sato, Idris Irfan, Fatulrachman, Takao Fujimura, Hiroaki Takimoto
- Organizer
  The 89th Annual Meeting of the Japanese society of Bacteriology
- Place of Presentation
  大阪国際交流センター、大阪市天王寺区
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-25670505
[Presentation] Endothelial cell invasion of a Mycobacterium leprae Mce1A protein expressed by the Escherichia coli AIDA autotransporter2013
- Author(s)
  Haslindah Dahlan, Naoya Sato, Fauzan Azhari Marzuki, Ahmad Haykal Abdurahman, Takao Fujimura
- Organizer
  The 16th Annual Meeting of Kitasato Microbial Academy
- Place of Presentation
  北里大学（相模原キャンパス）
- Year and Date
  2013-08-08
- Data Source
  KAKENHI-PROJECT-23659553
[Presentation] Vascular endothelial cell entry activity of Mycobacterium leprae depends on Mce1A protein2011
- Author(s)
  Ahmad Haykal Abdurahman, Naoya Sato, Sanako Tajima, Takao Fujimura, Kensei Katsuoka
- Organizer
  The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23659553
[Presentation] Mycobacterium leprae can invade in the human microvascular endothelial cells through the Mce1A protein2011
- Author(s)
  Tajima Sanako, Naoya Sato, Ahmad Haykal Abdurahman, Takao Fujimura, Kensei Katsuoka
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23659553
[Presentation] Invasion of human microvascular endothelial cells by Mycobacterium leprae through Mce1A protein2011
- Author(s)
  Naoya Sato, Ahmad Haykal Abdurahman, Toshiko Miyata, Takao Fujimura, Kensei Katsuoka
- Organizer
  Internal Union of Microbiological Societies 2011 Congress XIII International Congress of Bacteriology and Applied Microbiology
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23659553
[Presentation] The nasal epithelial cell invasion of Mycobacterium leprae may depend on unique amino acid redidues within the Mce1A protein
- Author(s)
  Haslindah Dahlan , Naoya Sato, Viesta Fadlitha Beby, Hiroaki Takimoto, Takao Fujimura.
- Organizer
  第43回日本免疫学会総会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-25670505
[Presentation] らい菌Mce1A蛋白外膜表示大腸菌の培養ヒト微小血管内皮細胞に対する侵入能の検討
- Author(s)
  佐藤直哉、藤村響男、Abdurahman Ahmad Haykal、Marzuki Fauzan Azhari、Bakri Haslindah Dahlan、勝岡憲生
- Organizer
  日本皮膚科学会第844回東京地方会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23659553

1. MASUZAWA Mikio (30129267)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. YOGI Yasuko (10210600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. SATO NAOYA (50276119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. MIYATA Toshiko (30260855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. EMOTO Masashi (70232981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAIKI Yoshikazu (10434622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KITA Eiji (90133199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FUKUDA Toshio (00173352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. AMANO Takafumi (30212567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJITA Yuhsuke (20238588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MITSUYAMA Masao (10117260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHIKAI Yasunobu (90158402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAWAMURA Ikuo (20214695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FUJITA Masashi (40115069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKANO Toshiaki (70306588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 増澤真実子 (20365084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 天野隆文 (50255288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 滝本博明 (00253534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. EMOTO Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. WATANABE Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KOYAMA Yu-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NYU Kiyosato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KIYAMA Takajyu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NISHIO Kazumasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. DAHLAN Haslindah

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. Viesta fadlitha beby

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. IDRIS Irfan

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. Fatulrachman

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. HURWITZ Robert

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KAUFMANN Stefan H.E.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. MOLLENKOPF Hans

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJIMURA Takao 藤村 響男

藤村 響男 フジムラ タカオ

Research Projects

Research Products

Co-Researchers

ハンセン病の感染様式に関る分子機構の解明とそれを標的とした感染防御ワクチンの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Medical applications of portable ozone water device for both maintenance of skin barrier function and hand hyagene in hospital-based nurses

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Vaccine for Hansen's Disease-Targeting the M.leprae Molecular Mechanism for Entry into Nasal Mucosal Epithelial CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene replacement system in slow growth mycobacteria to express green fluorescent protein and knock out the mce1A gene in recombinant strains of Mycobacterium leprae

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of natural ligand for invariant NKT cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内皮系超低増殖細胞によるライ菌の長期体外培養法の樹立

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Recombinant expression and functional analysis of the protein encoded by Mce 1A region of Mycobacterium leoraePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

表在性カンジダ症と慢性粘膜皮膚カンジダ症に於けるサイトカイン及びNO産生能の比較Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study of anti-CD3 X anti-tumor bispecific antibody therapy using helper/killer cells for malignant hemangioentothelioma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of virulence factor and the mechanisms for induction of cell-mediated immunity by intracellular bacterium, Listeria monocytogenes.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Recombinant Mycobacterium leprae protein associated with entry into mammalian cell of respiratory and skin components2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin components2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin components.2007

Author(s)

Journal Title

NAID

FUJIMURA Takao 藤村響男

藤村響男フジムラタカオ