Seiki Makoto 清木誠

… Alternative Names

SEIKI Makoto 清木誠

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Researcher Number	50226619
Other IDs
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 山口大学, 大学院医学系研究科, 教授 2016: 山口大学, 医学(系)研究科(研究院), 教授 2007: 京大, 再生医科学研究所, 助教授 2006: 熊本大学, 生命資源研究・支援センター, 教授 2006: Kyoto University, JST, Kondoh differentiation Signaling Project, Group Leader 1990: 東京大学, 医学部(医), 助手 1990: University of Tokyo, Associate Professor, 医学部・医学科, 助手
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / General anatomy (including Histology/Embryology) / Basic Section 48040:Medical biochemistry-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Biological Sciences / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Complex systems / Surgery of the organs maintaining homeostasis and related fields / General medical chemistry / General anatomy (including histology/embryology) … More Except Principal Investigator … More Basic Section 56030:Urology-related / Basic Section 56060:Ophthalmology-related / Urology / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 49010:Pathological biochemistry-related / Basic Section 55020:Digestive surgery-related / Basic Section 49030:Experimental pathology-related / Basic Section 56020:Orthopedics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 53010:Gastroenterology-related / Dermatology / Risk sciences of radiation/Chemicals / Immunology Less
Keywords	Principal Investigator YAP / メカノホメオスターシス / オルガノイド / 細胞外基質 / 再生 / メダカ / YAP メカノホメオスターシス / フィードバック / 力学恒常性 / がん免疫 … More / 立体臓器 / 重力 / 発生医学 / Hippoシグナル / 人工精巣 / 非閉塞性無精子症 / ゼブラフィッシュ / ECM / 数理モデル / 3次元臓器 / YAPメカノホメオスターシス / 免疫チェックポイント / 腸内細菌叢 / 人工腸管 / 臓器形成 / 時空間的ダイナミクス制御 / 体の 3D 建築工法 / コラーゲン / 力学特性 / 免疫チェックポイント療法 / リンパ節 / ARHGAP11A / 形態形成 / ３次元培養 / 炎症性サイトカイン / 角強膜線維柱帯細胞 / 力学制御 / 臓器 / ARHGAP / 脳の3次元構築 / 三次元構築 / KTR プローブ / 運命地図 / 細胞系譜 / 幹細胞 … More Except Principal Investigator 薬剤感受性 / YAP / 一次繊毛 / 繊毛病 / 薬剤感受性試験 / 免疫逃避 / 癌微小環境 / 膀胱癌 / オルガノイド / リプログラミング / ARAT / 骨微小環境 / 前立腺癌 / 去勢抵抗性前立腺癌 / Hippo経路 / 食物アレルギー / 食物蛋白誘発胃腸症 / 3次元電子顕微鏡 / 外節トリミング / 網膜変性 / ペルオキシソーム / がんオルガノイド / イメージング・マスサイトメトリー / メカノホメオスターシス / YAPレポーターマウス / magnetic tweezers法 / CODEX法 / 磁気ピンセット法 / PhenoCycler / がん免疫微小環境 / YAPの活性化 / メカノホメオスターシス / YAP活性化 / がん発症・進展 / 染色体異数性レスキュー / ゲノム編集 / 染色体異数性可塑性 / 染色体数レスキュー / 繊毛抑制遺伝子 / Patau症候群 / 13番染色体 / トリソミーレスキュー / iPS細胞 / in vitroモデル / 原発巣微小環境 / アビラテロン / CRPC / リン酸化制御酵素 / Zebrafish / 幹細胞活性化 / シグナル伝達 / 内在性網膜前駆細胞 / リン酸化制御 / CRMP / アクチンダイナミクス / タンパク質リン酸化 / タンパク質 / 内在性幹細胞 / 網膜再生 / がん免疫環境ニッチ / 3Dがんオルガノイド / 筋層浸潤性 / 3次元培養 / 癌オルガノイド / CTC / 血中循環腫瘍細胞 / 膵臓がん / 膵がん / 腸炎 / サイトカイン / 感染 / IL8 / 感染免疫 / IL-8 / サルモネラ / MHC / MST1/2 / ribD / Francisella tularensis / MAIT cell / Hippo / 網膜自己再生 / 再生医療 / 網膜再生医療 / 自然炎症 / 網膜前駆細胞 / 低分子化合物 / 眼炎症 / 網膜 / 自然再生 / 骨微少環境 / 骨芽細胞 / スフェロイド / 癌 / デルタ4アビラテロン / エンザルタミド / アパルタミド / M0CRPC / 前立腺がん / 腫瘍学 / delta 4 abiraterone / 去勢抵抗性前立腺癌前立腺 / 薬剤選択マーカー / リキッドバイオプシー / ３Ｄオルガノイド / ARHGAP18 / バイオマーカー / ARHGAP29 / 神経内分泌癌 / 3Dオルガノイド / 皮膚生理・生物学 / YAP/TAZ / 尋常性乾癬 / Revl / TLS DNA polvmerase / Medaka / Mutagenesis / Reverse Genetics / 紫外線 / 環境変動 / 逆遺伝学(Reverse Genetics) / 放射線 / 環境変異原 / 逆遺伝学 / メダカ / TILLING / 突然変異体 / Signal transduction / Ca^<2+> influx / Helper T cell / Suppressor T cell / Major histocompatibility complex / I-J / 拘束特異性 / 細胞間相互作用 / 抗原認識 / 二次元ゲル / 適応分化 / T細胞レセプタ- / シグナルトランスダクション / Caイオンの流入 / ヘルパ-T細胞 / 抑制性T細胞 / 主要組織適合遺伝子複合体 / IーJ Less

時空間ダイナミクス計測による臓器形成・再生におけるYAP力学恒常性制御機構の解明Principal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yamaguchi University
Mechanistic analysis of pathogenesis by systems analysis of YAP activation dynamics regulationPrincipal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yamaguchi University
Peroxisome-mediated trimming of outer segment in the retina for photoreceptor
- Principal Investigator
  
  宮本達雄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Yamaguchi University
Clarification of pathophysiology and risk factors for onset of food protein-induced enterocolitis syndrome
- Principal Investigator
  
  長谷川俊史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Yamaguchi University
Generation of an artificial testis to overcome azoospermiaPrincipal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Yamaguchi University
The body construction by you push me I push you back YAP mechanohomeostasisPrincipal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yamaguchi University
Analysis of YAP-mechanohomeostasis mediated regenerationPrincipal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yamaguchi University
膀胱癌における一次繊毛の中心体制御メカニズム解明による新たな治療戦略の創出
- Principal Investigator
  
  松本洋明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
A mini-organ culture system with cancer immune microenvironment recapitulating in vivoPrincipal Investigator
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
Pathological mechanism of ciliopathy in Patau syndrome using aneuploidy rescue technology
- Principal Investigator
  
  Miyamoto Tatsuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Yamaguchi University
Elucidation of molecular feedback mechanisms underlying mechano-homeostasis governing 3D organ formation and regenerationPrincipal Investigator
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yamaguchi University
がん発症・進展過程におけるYAPの活性化の機械的制御機構の解明
- Principal Investigator
  
  田尾嘉誉
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Development of new immunotherapy for metastatic pancreatic cancer by applying organoids derived from circulating tumor cells in blood.
- Principal Investigator
  
  Tanabe Tsuyoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Yamaguchi University
Development of a bladder cancer drug-sensitivity platform based on cancer niche formation including immune cell components
- Principal Investigator
  
  Matsumoto Hiroaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
Endogenous stem cell activation for retinal regeneration with minimal risk - Phosphorylation regulation of CRMP group -
- Principal Investigator
  
  Tokuda Kazuhiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Yamaguchi University
Development of opitimal drug screening using 3D in vitro prostate cancer organoid
- Principal Investigator
  
  Matsuyama Hideyasu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yamaguchi University
Interplay of brain morphogenesis and delelopmental clock by YAP mechano-homeostasisPrincipal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
Creation of lyph node organoids enabling mechanical control of immunityPrincipal Investigator
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
3D intestinal development and carcinogenesis by Hippo-YAP pathway
- Principal Investigator
  
  MUTSUNORI SHIRAI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
The induction of retinal progenitor cells by the control of natural inflammation
- Principal Investigator
  
  Sonoda Koh-Hei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
YAPメカノホメオスターシスによるほ乳類脳の3次元構築メカニズムの解明Principal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
Mechanism of YAP control of whole organ mechanical propertyPrincipal Investigator
- Principal Investigator
  
  SEIKI Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Yamaguchi University
A novel tissue culture system recapitulating in vivo physical propertiesPrincipal Investigator
- Principal Investigator
  
  SEIKI MAKOTO
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
Investigation of bone microenvironment using 3D-organoid model.
- Principal Investigator
  
  MATSUYAMA Hideyasu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Yamaguchi University
Analysis of gene regulartory network dynamics governing tissue mechanicsPrincipal Investigator
- Principal Investigator
  
  SEIKI Makoto
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Yamaguchi University
Elucidation of the Hippo-Yes-YAP pathway in psoriasis vulgaris using a three-dimensional skin model
- Principal Investigator
  
  FURUMOTO Hiroko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Yamaguchi University
Development of novel markers for drug screening and descovery of mechanism to neuroendocrine differentiation in castration resistant prostate cancer
- Principal Investigator
  
  MATSUMOTO Hiroaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Yamaguchi University
重力に抗した3D 臓器形成機構の解析Principal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Yamaguchi University
生体での神経幹細胞のふるまいを制御する遺伝学的基盤の解明Principal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto University
生体内での細胞動態のリアルタイム解析による幹細胞可塑性評価系の開発Principal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto University
生体内でのリアルタイム細胞系譜解析による幹細胞のプロスペクティブな同定Principal Investigator
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kumamoto University
Establishment of Reverse Genetics in Medaka : Screening for Induced Point Mutations in Medaka with TILLING
- Principal Investigator
  
  TODO Takeshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Molecular Identification and Immunological Significance of I-J Molecule.
- Principal Investigator
  
  TADA Tomio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  University of Tokyo

All 2022 2021 2020 2018 2017 2016 2006 2004

All Journal Article Presentation Book

[Book] The Hippo Pathway : Methods and Protocols (Methods in Molecular Biology)　14. Studying YAP-Mediated 3D Morphogenesis Using Fish Embryos and Human Spheroids2018
- Author(s)
  Hergovich, Alexander 他（分担）Yoichi Asaoka, Hitoshi Morita, Hiroko Furumoto, Carl-Philipp Heisenberg, and Makoto Furutani-Seiki
- Total Pages
  268
- Publisher
  Humana Pr Inc
- Data Source
  KAKENHI-PROJECT-16K10127
[Journal Article] AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells2022
- Author(s)
  Takao Kitagawa, Daiki Kobayashi, Byron Baron, Hajime Okita, Tatsuo Miyamoto, Rie Takai, Durga Paudel, Tohru Ohta, Yoichi Asaoka, Masayuki Tokunaga, Koji Nakagawa, Makoto Furutani-Seiki, Norie Araki, Yasuhiro Kuramitsu, Masanobu Kobayashi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 10 Pages: 0269077-0269077
- DOI
  10.1371/journal.pone.0269077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06899, KAKENHI-PROJECT-22K10229, KAKENHI-PROJECT-21H02718, KAKENHI-PROJECT-19K07352, KAKENHI-PROJECT-20K21845, KAKENHI-PUBLICLY-20H05037, KAKENHI-PROJECT-19H03772, KAKENHI-PROJECT-22F22111
[Journal Article] An intracellular pathogen Francisella tularensis escapes from host immunity by metabolic reprogramming.2022
- Author(s)
  Kensuke Shibata, Takashi Shimizu, Mashio Nakahara, Francois Legoux,Sho Yamasaki, Makoto Furutani-Seiki, Olivier Lantz, Masahisa Watarai, Mutsunori Shirai
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08424
[Journal Article] Gravity sensing in plant and animal cells.2021
- Author(s)
  Takahashi K, Takahashi H, Furuichi T, Toyota M, Furutani-Seiki M, Kobayashi T, Watanabe-Takano H, Shinohara M, Numaga-Tomita T, Sakaue-Sawano A, Miyawaki A, Naruse K.
- Journal Title
  
  NPJ Microgravity
  
  Volume: 7 Issue: 1 Pages: 2-2
- DOI
  10.1038/s41526-020-00130-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-20K08956, KAKENHI-PROJECT-20K21896, KAKENHI-PLANNED-18H05491, KAKENHI-PROJECT-19H03140, KAKENHI-PROJECT-18K09050, KAKENHI-PROJECT-18K19291, KAKENHI-PROJECT-19H03991
[Journal Article] ARHGAP29 expression may be a novel prognostic factor of cell proliferation and invasion in prostate cancer2020
- Author(s)
  Shimizu Kosuke、Matsumoto Hiroaki、Hirata Hiroshi、Ueno Koji、Samoto Masahiro、Mori Junichi、Fujii Nakanori、Kawai Yoshihisa、Inoue Ryo、Yamamoto Yoshiaki、Yano Seiji、Shimabukuro Tomoyuki、Furutani-Seiki Makoto、Matsuyama Hideyasu
- Journal Title
  
  Oncology Reports
  
  Volume: 44 Issue: 6 Pages: 2735-2745
- DOI
  10.3892/or.2020.7811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08956
[Journal Article] Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt12020
- Author(s)
  Iwanami Norimasa、Takeshita Kohei、Lawir Divine-Fondzenyuy、Suetake Isao、Tajima Shoji、Sikora Katarzyna、Trancoso In?s、?Meara Connor、Siamishi Iliana、Takahama Yousuke、Furutani-Seiki Makoto、Kondoh Hisato、Yonezawa Yasushige、Schorpp Michael、Boehm Thomas
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 7 Pages: 101260-101260
- DOI
  10.1016/j.isci.2020.101260
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05620, KAKENHI-PROJECT-18K06095, KAKENHI-PROJECT-20K08956
[Journal Article] Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model.2018
- Author(s)
  Shinagawa-Kobayashi Y, Kamimura K, Goto R, Ogawa K, Inoue R, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Sugitani S, Yanagi M, Fujisawa K, Nozawa Y, Koyama N, Nishina H, Furutani- Seiki M, Sakaida I, Terai S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496 Issue: 2 Pages: 556-561
- DOI
  10.1016/j.bbrc.2018.01.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19701, KAKENHI-PUBLICLY-16H01643, KAKENHI-PUBLICLY-17H05769, KAKENHI-PROJECT-17H04043, KAKENHI-PROJECT-16K15424, KAKENHI-PROJECT-17K09408, KAKENHI-PLANNED-26114005
[Journal Article] 再生医療-重力に抗した複雑な立体臓器の構築機構2017
- Author(s)
  浅岡　洋一, 古谷-清木　誠
- Journal Title
  
  季刊腎と骨代謝
  
  Volume: 30 Pages: 227-232
- Data Source
  KAKENHI-PROJECT-17K19701
[Journal Article] 再生医療-重力に抗した複雑な立体臓器の構築機構2017
- Author(s)
  浅岡　洋一, 古谷-清木　誠
- Journal Title
  
  季刊腎と骨代謝
  
  Volume: 30 Pages: 227-232
- Data Source
  KAKENHI-PUBLICLY-17H05769
[Journal Article] YAP is essential for 3D organogenesis withstanding gravity.2017
- Author(s)
  Asaoka Y, Nishina H, Furutani-Seiki M.
- Journal Title
  
  Dev Growth Differ.
  
  Volume: 59 Issue: 1 Pages: 52-58
- DOI
  10.1111/dgd.12338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15172, KAKENHI-PROJECT-15K09568, KAKENHI-PROJECT-16K08588, KAKENHI-PUBLICLY-16H01644, KAKENHI-PUBLICLY-17H05996, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H03982, KAKENHI-PUBLICLY-16H01643
[Journal Article] YAP mediated mechano-homeostasis ― conditioning 3D animal body shape2017
- Author(s)
  Yoichi Asaoka, Makoto Furutani-Seiki
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 49 Pages: 64-70
- DOI
  10.1016/j.ceb.2017.11.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08588, KAKENHI-PROJECT-17K19701, KAKENHI-PUBLICLY-16H01643, KAKENHI-PUBLICLY-16H01644, KAKENHI-PUBLICLY-17H05769, KAKENHI-PROJECT-17H04043, KAKENHI-PROJECT-15K09568
[Journal Article] 再生医療-重力に抗した複雑な立体臓器の構築機構2017
- Author(s)
  浅岡　洋一, 古谷-清木　誠
- Journal Title
  
  季刊腎と骨代謝
  
  Volume: 30 Pages: 227-232
- Data Source
  KAKENHI-PUBLICLY-16H01643
[Journal Article] 再生医療-重力に抗した複雑な立体臓器の構築機構2017
- Author(s)
  浅岡　洋一, 古谷-清木　誠
- Journal Title
  
  季刊腎と骨代謝
  
  Volume: 30 Pages: 227-232
- Data Source
  KAKENHI-PROJECT-17H04043
[Journal Article] Generation of medaka gene knockout models by target-selected mutagenesis.2006
- Author(s)
  Taniguchi Y, Furutani-Seiki M, Kamei Y, Todo T, Mitani H, et. al.
- Journal Title
  
  Genome Bid. 7(12)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201011
[Journal Article] A systematic genome-wide screen for mutations affecting organog enesis in Medaka,Oryzias latipes2004
- Author(s)
  M.Furutani-Seiki
- Journal Title
  
  Mech Dev 121
  
  Pages: 647-58
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16201011
[Journal Article] A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes.2004
- Author(s)
  Furutani-Seiki M, Todo T, et al.
- Journal Title
  
  Mech Dev. 121・7-8
  
  Pages: 647-658
- Data Source
  KAKENHI-PROJECT-16201011
[Journal Article] Identification of radiation-sensitive mutants in the Medaka, Oryzias latipes.2004
- Author(s)
  K. Aizawa, H. Mitani, T. Todo, M. Furutani-Seiki, et. al.
- Journal Title
  
  Mech Dev. 121(7-8)
  
  Pages: 895-902
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201011
[Journal Article] A systematic genome-wide screen for mutations affecting organogenesis in Medaha, Oryzias latipes.2004
- Author(s)
  M. Furutani-Seiki, T. Todo, H. Mitani, et. al.
- Journal Title
  
  Mech Dev. 121(7-8)
  
  Pages: 647-58
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201011
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body/organ shape2017
- Author(s)
  Masayuki Tokunaga, Yoichi Asaoka, Carl-Philipp Heisenberg,Hiroshi Nishina, Makoto Furutani-Seiki et al.
- Organizer
  The Hippo pathway across species and disciplines (EMBO workshop)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01643
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body/organ shape2017
- Author(s)
  Masayuki Tokunaga, Yoichi Asaoka, Carl-Philipp Heisenberg,Hiroshi Nishina, Makoto Furutani-Seiki et al.
- Organizer
  The Hippo pathway across species and disciplines (EMBO workshop)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04043
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body/organ shape2017
- Author(s)
  Masayuki Tokunaga, Yoichi Asaoka, Carl-Philipp Heisenberg, Hiroshi Nishina, Makoto Furutani-Seiki et al.
- Organizer
  The Hippo pathway across species and disciplines (EMBO workshop)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19701
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body/organ shape2017
- Author(s)
  Masayuki Tokunaga, Yoichi Asaoka, Carl-Philipp Heisenberg,Hiroshi Nishina, Makoto Furutani-Seiki et al.
- Organizer
  The Hippo pathway across species and disciplines (EMBO workshop)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05769
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body shape.2016
- Author(s)
  Furutani-Seiki M
- Organizer
  EMBO Symposium, Organoids
- Place of Presentation
  EMBL, Heidelberg, Germany
- Year and Date
  2016-10-12
- Data Source
  KAKENHI-PROJECT-16K15172
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body shape.2016
- Author(s)
  Furutani-Seiki M
- Organizer
  Santa Cruz Developmental Biology meeting
- Place of Presentation
  UC Santa Cruz, USA
- Year and Date
  2016-08-13
- Data Source
  KAKENHI-PROJECT-16K15172
[Presentation] YAP is essential for tissue tension to ensure vertebrate 3D body shape.2016
- Author(s)
  Furutani-Seiki M
- Organizer
  EMBO Symposium, Actin in Action
- Place of Presentation
  EMBL, Heidelberg, Germany
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K15172

1. 浅岡洋一 (10436644)

# of Collaborated Projects: 11 results

# of Collaborated Products: 7 results
2. MATSUYAMA Hideyasu (70209667)

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3. Miyamoto Tatsuo (40452627)

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5. FURUMOTO Hiroko (70311818)

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6. MATSUMOTO Hiroaki (60610673)

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7. 硲彰一 (50253159)

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51. 冨田拓郎

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Seiki Makoto 清木 誠

SEIKI Makoto 清木 誠

Research Projects

Research Products

Co-Researchers

時空間ダイナミクス計測による臓器形成・再生におけるYAP力学恒常性制御機構の解明Principal Investigator

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Mechanistic analysis of pathogenesis by systems analysis of YAP activation dynamics regulationPrincipal Investigator

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Generation of an artificial testis to overcome azoospermiaPrincipal Investigator

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The body construction by you push me I push you back YAP mechanohomeostasisPrincipal Investigator

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Analysis of YAP-mechanohomeostasis mediated regenerationPrincipal Investigator

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A mini-organ culture system with cancer immune microenvironment recapitulating in vivoPrincipal Investigator

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Elucidation of molecular feedback mechanisms underlying mechano-homeostasis governing 3D organ formation and regenerationPrincipal Investigator

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Seiki Makoto 清木誠

SEIKI Makoto 清木誠