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Yano Tomohiro  矢野 友啓

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… Alternative Names

YANO Tomohiro  矢野 友啓

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Researcher Number 50239828
Other IDs
External Links
Affiliation (Current) 2025: 東洋大学, 健康スポーツ科学部, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 東洋大学, 健康スポーツ科学部, 教授
2013 – 2022: 東洋大学, 食環境科学部, 教授
2010 – 2012: 東洋大学, 生命科学部, 教授
2008: National Institute of Health and Nutrition, 食品保険機能プログラム, プロジェクトリーダー
2007: National Institute of Health and Nutrition, National Institute of Health and Nutrition, Project Reader … More
2004 – 2006: 独立行政法人国立健康・栄養研究所, 室長
2005: National Institute of Health and Nutrition, Applied Food Research, Section Chief, 食品表示分析・規格研究部, 室長
1995 – 1996: 国立健康・栄養研究所, 応用食品部, 主任研究官 Less
Review Section/Research Field
Principal Investigator
Eating habits, studies on eating habits / Basic Section 59040:Nutrition science and health science-related / Eating habits / Home economics/Human life / Applied veterinary science / 家政学
Except Principal Investigator
Basic Section 59020:Sports sciences-related / Basic Section 08030:Family and consumer sciences, and culture and living-related
Keywords
Principal Investigator
BBI / コネキシン43 / connexin 43 / 前立腺癌 / 大豆由来成分 / 癌予防食材 / 前立腺がん予防法 / TRAIL/DR5経路 / STAT3 / 免疫チェックポイント … More / MICA/MICB / NKG2D / TRAIL/DR5 / 殺細胞効果 / NK細胞 / 前立腺がん幹細胞 / 中皮腫予防 / 機能性食素材 / 3次元培養 / 幹細胞マーカー / アポトーシス / Nrf1 / 細胞死 / トコトリエノール誘導体 / オートファジー / プロテオソーム / 小胞体ストレス / 薬剤耐性 / Tumorsphere / 中皮腫幹細胞 / 遺伝子多型 / MTHFR / MTHFR遺伝子多型 / 抗酸化成分 / 骨芽細胞 / ペントシジン / ホモシステイン / リジルオキシダーゼ / MTHFR遺伝子多型 / 骨折 / 骨質劣化 / ファイトケミカル / 低酸素条件 / 癌予防・治療 / 癌幹細胞 / がん予防食素材 / 前立腺がん / がん幹細胞 / cancer prevention foor / food compnent form soybeans / 癌予防食品 / gap junctions / intercellular communication / tumor suppressor gene / connexin 26 / canine mammary tumors / コネキシン26 / ギャップ結合 / 細胞間情報伝達 / 癌抑制遺伝子 / コンキシン26 / 犬乳腺腫瘍 / Cell proliferation / Ornithine decarboxylase / ras gene / Vitamin E / Chemoprevention / Lung adenocarcinoma / 細胞増殖 / オルニチン脱炭酸酵素 / ras遺伝子 / ビタミンE / 化学予防 / 肺腺がん / 癌予防食素材 / 分子標的予防 / ELISA法 / 生体利用性 / 中皮腫 … More
Except Principal Investigator
一塩基多型 / 女性アスリート / 疲労骨折 / ホモシステイン / メタボロミクス / 骨格筋 / 乳酸菌 / サルコペニア / ポストバイオティクス / Homocysteine / 血漿Hcy濃度 / 一過性運動 / メタボローム解析 / メチレンテトラヒドロ葉酸還元酵素 Less
  • Research Projects

    (13 results)
  • Research Products

    (97 results)
  • Co-Researchers

    (12 People)
  •  ポストバイオティクスに立脚したサルコペニア予防食品素材の開発

    • Principal Investigator
      石田 達也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Toyo University
  •  Investigation of genetic variation and exercise-induced Hcy metabolic kinetics for the prevention of stress fractures in female athletes.

    • Principal Investigator
      峰松 明也子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Toyo University
  •  Factors influencing plasma homocysteine levels for the prevention of stress fractures in female athletes

    • Principal Investigator
      Minematsu Ayako
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kinjo Gakuin University
  •  Establishment of a new preventive strategy based on the interaction of NK cells and prostate cancer stem cellsPrincipal Investigator

    • Principal Investigator
      Yano Tomohiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Toyo University
  •  Establishment of new functional food ingredients which are effective for prevention of mesothelioma due to regulation of mesothelioma stem cellsPrincipal Investigator

    • Principal Investigator
      Yano Tomohiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Toyo University
  •  Establishment of a screening system to select cancer preventive ingredient based on a new carcinogenesis theoryPrincipal Investigator

    • Principal Investigator
      YANO TOMOHIRO
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Eating habits
    • Research Institution
      Toyo University
  •  Establishment of a new approach to prevent fracture caused by loss of bone qualityPrincipal Investigator

    • Principal Investigator
      YANO TOMOHIRO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Home economics/Human life
    • Research Institution
      Toyo University
  •  Establishment of a new food ingredient for cancer prevention based on molecular targeting prevetionPrincipal Investigator

    • Principal Investigator
      YANO TOMOHIRO
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Eating habits
    • Research Institution
      Toyo University
  •  Bioavailability evaluation on a new food component from soybeansPrincipal Investigator

    • Principal Investigator
      YANO Tomohiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Toyo University
  •  新たな食素材を用いた中皮腫予防食品の開発Principal Investigator

    • Principal Investigator
      矢野 友啓
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      National Institute of Health and Nutrition
  •  Possibility of a new functional food component from soybeansPrincipal Investigator

    • Principal Investigator
      YANO Tomohiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      National Institute of Health and Nutrition
  •  Determination of connexin gene contributing to suppression of canine mammary carcinogenesis and investigation of the mechanismPrincipal Investigator

    • Principal Investigator
      YANO Tomohiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      National Institute of Health and Nutrition
  •  THE ESTIMATION OF A USEFUL LEVEL OF VITAMINE INTAKE AGAINST THE PREVENTION OF LUNG ADENOCARCINOMAPrincipal Investigator

    • Principal Investigator
      YANO Tomohiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      家政学
    • Research Institution
      THE NATIONAL INSTITUTE OF HEALTH&NUTRITION

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] ビタミンE研究の進歩XVII2016

    • Author(s)
      塩澤伸哉、佐藤知晶、並木梢、金子沙妃、佐藤綾美、佐藤洋美、矢野友啓
    • Total Pages
      148
    • Publisher
      ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Book] ビタミンE研究の進歩XVII2016

    • Author(s)
      河野翔、山田和佳奈、石塚綾、関根美季、太田昌子。矢野友啓
    • Total Pages
      148
    • Publisher
      ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Journal Article] Changes in homocysteine and non-mercaptoalbumin levels after acute exercise: a crossover study2023

    • Author(s)
      Akiho Shinagawa, Tomoki Yamazaki, Ayako Minematsu, Naho Serizawa, Yuri Hosoi, Yusuke Ninomiya, Yuichi Miyakoshi, Tomohiro Yano, Masako Ota
    • Journal Title

      BMC Sports Science, Medicine and Rehabilitation

      Volume: 15 Issue: 1

    • DOI

      10.1186/s13102-023-00656-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11347
  • [Journal Article] α-Tocotrienol and Redox-Silent Analogs of Vitamin E Enhances Bortezomib Sensitivity in Solid Cancer Cells through Modulation of NFE2L12023

    • Author(s)
      Ishii K, Hido M, Sakamura M, Virgona N, Yano T.
    • Journal Title

      Int J Mol Sci

      Volume: 24 Issue: 11 Pages: 9382-9382

    • DOI

      10.3390/ijms24119382

    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Journal Article] CHEMORESISTANCE RELATED TO HYPOXIA ADAPTATION IN MESOTHELIOMA CELLS FROM TUMOR SPHEROIDS2022

    • Author(s)
      Endoh D, Ishii K, Kohno K, Virgona N, Miyakoshi Y, Yano T, Ishida T.
    • Journal Title

      Exp Oncol

      Volume: 44 Issue: 2 Pages: 121-125

    • DOI

      10.32471/exp-oncology.2312-8852.vol-44-no-2.18045

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Journal Article] Short-Term Combined Intake of Vitamin B2 and Vitamin E Decreases Plasma Homocysteine Concentrations in Female Track Athletes2022

    • Author(s)
      Akiho Shinagawa, Naho Serizawa, Tomoki Yamazaki, Ayako Minematsu, Yuichi Miyakoshi, Tomohiro Yano, Masako Ota
    • Journal Title

      Dietetics

      Volume: 1 Issue: 3 Pages: 216-226

    • DOI

      10.3390/dietetics1030019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11347
  • [Journal Article] Endurance exercise increases next-day fasting plasma homocysteine concentrations in female long-distance runners2022

    • Author(s)
      Ayako Minematsu, Naho Serizawa, Akiho Shinagawa, Tomoki Yamazaki, Yuichi Miyakoshi, Tomohiro Yano, Masako Ota
    • Journal Title

      Journal of Clinical Physiology

      Volume: 52 Pages: 151-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K11347
  • [Journal Article] 喫煙による肺発がんに対するalphaートコフェロールの抑制効果2021

    • Author(s)
      石田達也、矢野友啓
    • Journal Title

      ビタミン

      Volume: 95

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Journal Article] Effects of Alpha-Connexin Carboxyl-Terminal Peptide (aCT1) and Bowman-Birk Protease Inhibitor (BBI) on Canine Oral Mucosal Melanoma (OMM) Cells.2021

    • Author(s)
      Sato A, da Fonseca IIM, Nagamine MK, de Toledo GF, Olio R, Hernandez-Blazquez FJ, Yano T, Yeh ES, Dagli MLZ.
    • Journal Title

      Front Vet Sci.

      Volume: 8 Pages: 670451-670451

    • DOI

      10.3389/fvets.2021.670451

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Journal Article] NK Cells Can Preferentially Target Prostate Cancer Stem-like Cells via the TRAIL/DR5 Signaling Pathway2021

    • Author(s)
      Seki T, Shimizu Y, Ishii K, Takahama Y, Kato K, Yano T.
    • Journal Title

      Biomolecules

      Volume: 11 Issue: 11 Pages: 1702-1702

    • DOI

      10.3390/biom11111702

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Journal Article] The effect of Bowman-Birk inhibitor from soybeans on the sensitivity of prostate cancer stem-like cells to anti-androgen agent2020

    • Author(s)
      Endo D, Kaneko S, Kohno S, Sato A, Nantiga V, Yano T.
    • Journal Title

      Food Science and Technology

      Volume: 26

    • NAID

      130007904094

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Journal Article] A Redox-Inactive Derivative of Tocotrienol Suppresses Tumor Growth of Mesothelioma Cells in a Xenograft Model2019

    • Author(s)
      Sato A, Arai T, Fusegi M, Ando A, Yano T.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 42 Issue: 6 Pages: 1034-1037

    • DOI

      10.1248/bpb.b18-00924

    • NAID

      130007657679

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2019-06-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Journal Article] Combination Effect of Bowman-Birk Inhibitor and α-Tocopheryl Succinate on Prostate Cancer Stem-Like Cells2019

    • Author(s)
      Kaneko S, Yamazaki T, Kohno K, Sato A, Kato K, Yano T.
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 65 Issue: 3 Pages: 272-277

    • DOI

      10.3177/jnsv.65.272

    • NAID

      130007670195

    • ISSN
      0301-4800, 1881-7742
    • Year and Date
      2019-06-30
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11058, KAKENHI-PROJECT-19K07719
  • [Journal Article] A Succinate Ether Derivative of Tocotrienol Enhances Dickkopf-1 Gene Expression through Epigenetic Alterations in Malignant Mesothelioma Cells2018

    • Author(s)
      Sato Ayami、Ueno Haruka、Fusegi Momoka、Kaneko Saki、Kohno Kakeru、Virgona Nantiga、Ando Akira、Sekine Yuko、Yano Tomohiro
    • Journal Title

      Pharmacology

      Volume: 102 Issue: 1-2 Pages: 26-36

    • DOI

      10.1159/000489128

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Journal Article] Inhibitory effect of a redox-silent analogue of tocotrienol on hypoxia adaptation in prostate cancer cells.2017

    • Author(s)
      shiozawa N, Yano T et al.
    • Journal Title

      Anticancer Drugs

      Volume: 28 Issue: 3 Pages: 289-297

    • DOI

      10.1097/cad.0000000000000460

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Journal Article] Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat32015

    • Author(s)
      Sugahara R, Yano T et al.
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 61 Issue: 6 Pages: 497-501

    • DOI

      10.3177/jnsv.61.497

    • NAID

      130005125488

    • ISSN
      0301-4800, 1881-7742
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Journal Article] 前立腺がん発症率に対するビタミンE摂取の影響ーその無作為化比較「試験のメタ分析による評価2013

    • Author(s)
      谷畑尚吾、小林三那子、関根美季、松谷紀枝子、太田昌子、佐藤綾美、矢野友啓
    • Journal Title

      ビタミン

      Volume: 87 Pages: 359-363

    • NAID

      110009624884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560040
  • [Journal Article] ビタミンE摂取によるがん発症率及び死亡率への影響ー無作為化比較試験のシステマチイックレビュー・メタ分析ー2013

    • Author(s)
      小林三那子、関根美季、先崎裕美、太田昌子、矢野友啓、卓興鋼
    • Journal Title

      Clinical and Functional Nutriology

      Volume: 5 Pages: 85-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560040
  • [Journal Article] Yes is a central mediator of cell growth in malignant mesothelioma cells.2012

    • Author(s)
      Ayami Sato(Tomohiro Yano)
    • Journal Title

      Onocology Reports

      Volume: 28 Pages: 1889-1893

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Journal Article] Yes is a central mediator of cell growth in malignant mesothelioma cells.2012

    • Author(s)
      Sato A, Sekine M, Virgona N, Ota M, Yano T.
    • Journal Title

      Oncol Rep.

      Volume: 28 Issue: 5 Pages: 1889-1893

    • DOI

      10.3892/or.2012.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Journal Article] owman-birk preotease inihitor from soybeans enhaces cisplatin-induced cytotoxicity inhuman mesothelioma ce2011

    • Author(s)
      Kashiwagi K, Yano T, et al
    • Journal Title

      Exp Ther Med

      Volume: 2 Issue: 4 Pages: 719-724

    • DOI

      10.3892/etm.2011.270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Journal Article] Bowman-Birk protease inhibitor from soybeans enhances cisplatin-induced cytotoxicity in human mesothelioma cells.2011

    • Author(s)
      Kashiwagi K, Virgona N, Yamada J, Sato A, Ota M, Yazawa T, Yano T.
    • Journal Title

      Exp Ther Med.

      Volume: 2 Pages: 719-724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Journal Article] 大豆由来のBowman-birk protease inhibitor(BBI)の抗がん作用について2011

    • Author(s)
      矢野友啓
    • Journal Title

      ILSI Japan

      Volume: 104 Pages: 17-21

    • NAID

      40018766285

    • Data Source
      KAKENHI-PROJECT-22500754
  • [Journal Article] Bowman-birk protease inhibitor from soy beans enhances cisplatin-Induced cytotoxicity in human mesothelioma cells2011

    • Author(s)
      Kashiwagi K, Yano T, et al.
    • Journal Title

      Exp.Ther.Med.

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Journal Article] Cx43-dependent tumor-suppressing effect of the Bowman-Birk protease inhibitor on M5076 ovarian sarcoma-bearing mice2008

    • Author(s)
      Sakurai N, Yano T, et al.
    • Journal Title

      Molecular Medicine reports 1

      Pages: 689-693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20650122
  • [Journal Article] Effects of a single-dose administration of Bowman-Birk in-Hibitor concentrate on anti-proliferation and inhabitation Of metastasis in M5076 ovarian sarcoma-bearing mice2008

    • Author(s)
      Sakurai N, Yano T, et al.
    • Journal Title

      Molecular Medicine reports 1

      Pages: 903-907

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20650122
  • [Journal Article] がん抑制遺伝子(コネキシン43)の発現・機能回復による中皮腫発生抑制に関する研究-大豆由来のBowman-Birk protease inhibitorを用いた検討-2007

    • Author(s)
      矢野友啓、柏木維人、佐藤洋美
    • Journal Title

      大豆たん白質研究 10

      Pages: 110-115

    • NAID

      40015776893

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean: involvement of conenxin 432007

    • Author(s)
      Saito T, Yano T, et. al.
    • Journal Title

      Cancer Letters 253

      Pages: 249-257

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] がん抑制遺伝子(コネキシン43)の発現・機能回復による中皮腫発生抑制に関する研究-大豆由来のBowman-Birk protease inhibitorを用いた検討-2007

    • Author(s)
      矢野 友啓、柏木 維人、佐藤 洋美
    • Journal Title

      大豆たん白質研究 10

      Pages: 110-115

    • NAID

      40015776893

    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 432007

    • Author(s)
      Saito T, Yano T et al.
    • Journal Title

      Cancer Letters (In press)

    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] Negative growth contiol of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean: involvement of conenxin 432007

    • Author(s)
      Saito T, Yano T, et. al.
    • Journal Title

      Cancer Letters 253

      Pages: 249-253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean:involvement of conenxin 432007

    • Author(s)
      Saito T, Yano T, et. al.
    • Journal Title

      Cancer Letters 253

      Pages: 249-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] Negative growth control of BBI from soybean against mesothelioma based on restoration of connexin 43-dependent tumor-suppressive effect.2007

    • Author(s)
      Yano T, Kashiwagi K, Sato H
    • Journal Title

      Soy Protein Research 10

      Pages: 115-11119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Journal Article] Expression patterns of connexin 26 and connexin 43 mRNA in canine benign and malignant mammary tumors.2006

    • Author(s)
      Gotoh H, Asano R, Yano T et al.
    • Journal Title

      The Veterinary Journal (In press)

    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Expression patterns of connexin 26 and connexin 43 mRNA in canine benign and malignant mammary tumors.2006

    • Author(s)
      Gotoh H, Asano R, Yano T et al.
    • Journal Title

      The Veterinary Journal (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] 癌抑制遺伝子(コネキシン)の機能回復をターゲットにした癌化学予防に関する研究(II)-大豆由来のBowman-Birk inhibitorを用いた検討-2006

    • Author(s)
      矢野友啓, 鈴木一由, 浅野隆司
    • Journal Title

      大豆たんぱく質研究 (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Restoration of connexin 43 by Bowman-Birk protease inhibitor in M5076 bearing mice.2005

    • Author(s)
      Suzuki K, Asano R, Yano T et al.
    • Journal Title

      Oncology Reports 13

      Pages: 1247-1250

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] 癌抑制遺伝子(コネキシン)の機能回復をターゲットにした癌化学予防に関する研究-大豆由来のBowman-Birk inhibitorを用いた検討-2005

    • Author(s)
      矢野友啓, 鈴木一由, 浅野隆司
    • Journal Title

      大豆たんぱく質研究 8

      Pages: 113-116

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Connexin 32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell line2005

    • Author(s)
      Fujimoto E., Yano T et al.
    • Journal Title

      Oncogene (In press)

    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Chemoprevention of Bowman-Birk inhibitor from soy bean against cancers based on restoration of connexin 43-dependent tumor-suppressive effect.2005

    • Author(s)
      Yano T, Suzuki K, Asano R
    • Journal Title

      Soy Protein Research 8

      Pages: 113-116

    • NAID

      40015330119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Cytotoxic effect of Her-2/Her-1 inhibitor PKI-166 on renal cancer cells expressing connexin 32 gene2005

    • Author(s)
      Fujimot E., Yano T et al.
    • Journal Title

      J.Pharmacol.Sci. (In press)

    • NAID

      10025726292

    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] A Src family inhibitor (PP1) potentiates tumor-suppressive effect of connexin 32 gene in renal cancer cells2005

    • Author(s)
      Fujimoto E., Yano T et al.
    • Journal Title

      Life Sciences (In press)

    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Expression patterns of connexin 26 and connexin 43 mRNA in canine benign and malignant mammary tumors

    • Author(s)
      Gotoh H, Asano R, Yano T et al.
    • Journal Title

      Veterinary J (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Journal Article] Chemoprevention of Bowman-Birk inhibitor from soy bean against cancers based on restoration of connexin 43-dependent tumor-suppressive effect (II).

    • Author(s)
      Yano T, Suzuki K, Asano R
    • Journal Title

      Soy Protein Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580259
  • [Patent] 抗中皮腫用剤の殺細胞効果増強剤2007

    • Inventor(s)
      矢野 友啓
    • Industrial Property Rights Holder
      矢野 友啓
    • Filing Date
      2007-09-25
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Patent] 抗中皮腫用剤の殺細胞効果増強剤2007

    • Inventor(s)
      矢野 友啓
    • Industrial Property Rights Holder
      矢野 友啓
    • Filing Date
      2007-09-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] 去勢抵抗性前立腺がん、すい臓がんにおけるトコトリエノールのNRF3阻害効果と補完代替成分としての可能性2023

    • Author(s)
      石井亨太、矢野友啓
    • Organizer
      第21回日本機能性食品医用学会
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Presentation] ヒト前立腺がん細胞におけるδートコトリエノールによるHIF阻害効果の検討2023

    • Author(s)
      田内優乃、石井亨太、河野翔、矢野友啓
    • Organizer
      第21回日本機能性食品医用学会
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Presentation] ナチュラルキラー(NK)細胞は去勢抵抗性前立腺がん幹細胞を優先的に傷害する2022

    • Author(s)
      関大河、矢野友啓
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Presentation] 悪性胸膜中皮腫スフェロイドの治療抵抗性上昇は低酸素ストレスに起因するか?2021

    • Author(s)
      遠藤大輝、矢野友啓
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] Death receptor pathway in NK cells regulate prostate cancer stem cells2021

    • Author(s)
      関大河、矢野友啓
    • Organizer
      第80回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Presentation] NK Cells Preferentially Target Prostate Cancer Stem-like Cells2021

    • Author(s)
      Seki T, Yano T
    • Organizer
      Sydney Cancer Conference 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K11638
  • [Presentation] 3次元培養システムによる悪性胸膜中皮腫スフェロイドとがん幹細胞性との関連2020

    • Author(s)
      遠藤大輝、矢野友啓
    • Organizer
      2020年癌学会総会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] Can T3E overcome chemoresistance of mesothelioma cells via the inhibition of endoplasmic reticulum stress?2020

    • Author(s)
      Ishii K, Yano T
    • Organizer
      2020 annual meeting of JCA
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] 悪性中皮腫細胞株における低酸素誘導因子HIFを標的としたアナト-由来トコトリエノールの腫瘍抑制作用解析2020

    • Author(s)
      河野翔、矢野友啓
    • Organizer
      日本ビタミン学会大72回大会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] タンパク関連メカニズムに焦点をあてたビタミンE誘導体T3Eの抗中皮腫作用の検討2020

    • Author(s)
      伏木桃花、河野翔、中野渡真奈、矢野友啓
    • Organizer
      第31回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] ビタミンE同族体の悪性胸膜中皮腫細胞への影響2020

    • Author(s)
      荒井恒毅、矢野友啓
    • Organizer
      2020年癌学会総会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] 低酸素環境下の中皮腫細胞株を標的にしたトコトリエノールの抗がん作用解析2020

    • Author(s)
      河野翔、矢野友啓
    • Organizer
      第31回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] A new preventive strategy for targeting gap junction in prostate cancer stem cells2019

    • Author(s)
      Endo D, Yano T. Kaneko S, Kato K, Amano T
    • Organizer
      The International Gap Junction Conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] T3Eは悪性中皮腫細胞の化学療法抵抗性を克服するために有効か?2019

    • Author(s)
      伏木桃花、矢野友啓
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] ビタミンE誘導体による遺伝子多型に基づいた悪性中皮腫細胞死耐性の克服2019

    • Author(s)
      伏木桃花、河野翔、矢野友啓
    • Organizer
      第30回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] Can MTHFR C677T SNP affect anti-mesothelioma effect via ER stress?2018

    • Author(s)
      Momoka Fusegi, Kakeru Kohno, Tomohiro Yano
    • Organizer
      Sydney Cancer Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] MTHFR C677T SNPは小胞体ストレスを介した抗中皮腫効果に影響を及ぼすか?2018

    • Author(s)
      伏木桃花、矢野友啓
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K11058
  • [Presentation] 骨芽細胞培養系を用いたオリーブポリフェノールにおけるリジルオキシダーゼmRNAレベルに及ぼす影響2017

    • Author(s)
      山田和佳奈, 河野翔, 石塚綾, 太田昌子, 矢野友啓
    • Organizer
      第15回日本機能性食品医用学会
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] The effect of Advanced glycation end-products on bone-quality deterioration and possible prevention with Tocotrienol2017

    • Author(s)
      Aya Ishistuka, Masako Ota. Tomohiro Yano
    • Organizer
      10th Asia Pacific Conference on Clinical Nutrition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] がん幹細胞仮説に基づく前立腺がんのTRFによる根本的予防の検討2017

    • Author(s)
      塩澤伸哉、矢野友啓他
    • Organizer
      第28回ビタミンE研究会
    • Place of Presentation
      東洋大学白山キャンパス(東京都文京区)
    • Year and Date
      2017-01-21
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] Examination of risk factors related to stress fractures in female, long-distance runners2017

    • Author(s)
      Ayako Minematsu, Tomohiro Yano, Masako Ota
    • Organizer
      10th Asia Pacific Conference on Clinical Nutrition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] Effects of olive polyphenol on prevention of deterioration of bone quality2017

    • Author(s)
      Wakana Yamada, Masako Ota, Tomohiro Yano
    • Organizer
      10th Asia Pacific Conference on Clinical Nutrition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] 糖化ストレスによる骨質劣化への影響とトコトリエノールによる予防の可能性2017

    • Author(s)
      石塚綾、矢野友啓他
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-25
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] 終末糖化産物のリジルオキシダーゼを標的とした骨質劣化作用に対するトコトリエノールの予防効果2017

    • Author(s)
      石塚綾, 河野翔, 山田和佳奈, 宮西伸光, 矢野友啓
    • Organizer
      第15回日本機能性食品医用学会
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] ビタミンE同族体における骨質改善作用としての可能性の検証2017

    • Author(s)
      山田和佳菜、矢野友啓他
    • Organizer
      第28回ビタミンE研究会
    • Place of Presentation
      東洋大学白山キャンパス(東京都文京区)
    • Year and Date
      2017-01-20
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] Possibility of prostate cancer prevention based on cancer stem cell theory2016

    • Author(s)
      Shiozawa N, Yano T et al.
    • Organizer
      AACR2016
    • Place of Presentation
      New orleans, LA, USA
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] Tocotrienol-rich fraction の骨質劣化予防成分としての可能性の検討2016

    • Author(s)
      河野翔、山田和菜奈、太田昌子、矢野友啓
    • Organizer
      第27回ビタミンE研究会
    • Place of Presentation
      香川県民ホール(香川県高松市)
    • Year and Date
      2016-01-08
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] Possibility of prosate cancer prevention with aatrgeting cancer stem theory2016

    • Author(s)
      Shiozawa N, Yano T et al.
    • Organizer
      JCA2016
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] がん幹細胞仮説に基づくTRFによる前立腺がん予防の可能性2016

    • Author(s)
      塩澤伸哉、矢野友啓他
    • Organizer
      日本ビタミン学会第68回大会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] がん幹細胞を標的にしたtocotrienol-rich fraction による前立腺がん予防の可能性2016

    • Author(s)
      塩澤伸哉、菅原綾介、佐藤知晶、矢野友啓
    • Organizer
      第27回ビタミンE研究会
    • Place of Presentation
      香川県民ホール(香川県高松市)
    • Year and Date
      2016-01-08
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] 骨芽細胞培養系を用いたアナトー由来トコトリエノールの骨質改善作用の検討2016

    • Author(s)
      河野翔、矢野友啓他
    • Organizer
      日本ビタミン学会第68回大会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] Investigating the possibility of tocotrienol-rich fraction in the maintenance of bone quality-a preliminary study2015

    • Author(s)
      Kono K, Ota M, Yano T
    • Organizer
      12th Asia Congress of Nutrition
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-05-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02885
  • [Presentation] がん幹細胞を標的とした前立腺がん予防法の可能性2015

    • Author(s)
      塩澤伸哉、矢野友啓
    • Organizer
      第62回日本栄養改善学会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] A possible role of tocotrienol-rich fraction as an anti-cancer agent in prostate cancer2015

    • Author(s)
      Shiozawa S, Sugahara A, Sato Y, Uchida A, Sato A, Ota M, Yano T
    • Organizer
      12th Asia Congress of Nutrition
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12329
  • [Presentation] ビタミンE摂取によるがん発症率及び死亡率への影響ー無作為化比較試験のシステマチイックレビュー・メタ分析ー2013

    • Author(s)
      小林三那子、佐藤綾美、矢野友啓
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-25560040
  • [Presentation] 前立腺癌におけるビタミンEの効果ー無作為化比較試験と in vitro study-2013

    • Author(s)
      谷畑尚吾、矢野友啓
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-25560040
  • [Presentation] キモトリプシン阻害活性を指標とする大豆食品中のBBIの定量2012

    • Author(s)
      佐藤綾美、矢野善久、矢野友啓
    • Organizer
      2012食品分析研究会
    • Place of Presentation
      東洋大学白山キャンパス(東京)
    • Year and Date
      2012-09-05
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Presentation] Bowman-birk protease inhibitorによる中皮腫の持つシスプラチン耐性改善効果2012

    • Author(s)
      矢野友啓, 他
    • Organizer
      日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Presentation] Bowman-birk protease inhibitor による中皮腫の持つシスプラチン耐性改善効果2012

    • Author(s)
      矢野友 啓 、佐藤綾美、関根美季、太田昌子
    • Organizer
      第132回日本薬学会
    • Place of Presentation
      北海道大学(札 幌)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Presentation] BBIによる中皮腫の薬剤耐性改善作用2010

    • Author(s)
      柏木維人、矢野友啓
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Presentation] BBIによる中皮腫の薬剤耐性の改善作用2010

    • Author(s)
      柏木維人、矢野友啓
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22500754
  • [Presentation] New Mechanism on Anti-carcinogenic Effect of Bowman-Birk Protease Inhibitor(BBI)from Soybeans2007

    • Author(s)
      Yano T、Saito T、Kashiwagi K、Hagiwara H、Sato H
    • Organizer
      100th Amual Meeting of American Association for Cancer Research
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2007-04-17
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] Fast D, Roh-Schmidt H, Restoration of connexin 43-dependent tumor-suppressive effect by Bowman-Birk protease inhibitor from soybeans.2007

    • Author(s)
      Yano T, Kashiwagi K, Sato H
    • Organizer
      ICoFF2007
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-11-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] A New Mechanism on Anti-carcinogenic Effect of Bowman-Birk Protease Inhibitor(BBI) from Soybeans2007

    • Author(s)
      Yano T, Saito T, Kashiwagi K, Hagiwara H, Sato H
    • Organizer
      100th AACR
    • Place of Presentation
      LA,USA
    • Year and Date
      2007-04-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] New Mechanism on Anti-carcinogenic Effect of Bowman-Birk Protease Inhibitor (BBI) from Soybeans2007

    • Author(s)
      Yano T、 Saito T、 Kashiwagi K、 Hagiwara H、 Sato H
    • Organizer
      100th Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2007-04-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] Anti-tumor effects of Bowman-Birk protease inhibitor from soybean : involvement of connexin 43.2007

    • Author(s)
      Yano T
    • Organizer
      36th UJNR
    • Place of Presentation
      Tsukuba
    • Year and Date
      2007-10-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] Contribution of connexin 43 to BBI-dependent growth control of osteosarcoma U2OS cells.2006

    • Author(s)
      Saito T, Sato H, Hagiwara H, Virgona NSuzuki K, Yano T
    • Organizer
      International Conference on Physiologocal and Pathological Importance.
    • Place of Presentation
      Gap Junctions
    • Year and Date
      2006-11-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] The effects of Bowman-Birk Protease inhibitor concentrate BBIC) on anti-proliferation and inhbition of metastasis in M5076 bearing mice.2006

    • Author(s)
      Sano Y, Yoshimura H, Nishimura Y, Sakurai N, Suzuki , Yano T
    • Organizer
      International Conference on Physiologocal and Pathological Importance.
    • Place of Presentation
      Gap Junctions
    • Year and Date
      2006-11-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500618
  • [Presentation] Tocotrienol-rich fraction from annatto acts as an anti-cancer agent against prostate cancer

    • Author(s)
      Ryosuke Sugahara, Ayami Sato, Tomohiro Yano
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25560040
  • [Presentation] 前立腺がんに対するトコトリエノール高含有フラクションの抗がん作用の解析

    • Author(s)
      菅原綾介、佐藤綾美、太田昌子、矢野友啓
    • Organizer
      第26回ビタミンE研究会
    • Place of Presentation
      北里大学薬学部(東京都、港区)
    • Year and Date
      2015-01-09 – 2015-01-10
    • Data Source
      KAKENHI-PROJECT-25560040
  • [Presentation] キモトリプシン阻害活性を指標とする大豆食品中のBBIの定量

    • Author(s)
      佐藤綾美(矢野友啓)
    • Organizer
      食品分析研究会
    • Place of Presentation
      東洋大学白山キャンパス(東京)
    • Data Source
      KAKENHI-PROJECT-22500754
  • 1.  Minematsu Ayako (40712998)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  太田 昌子 (40442058)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 3.  YANO Yoshihisa (20230287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 4.  ICHIKAWA Tomio (10028839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  ASANO Ryuji (40151047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 6.  YAMADA Kazuhiko (60158178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  佐藤 洋美 (30506887)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  宮越 雄一 (00343533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  加藤 和則 (60233780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  石田 達也 (90356262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  根建 拓 (50375200)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KOHNO Kakeru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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