YAMAMOTO Daisuke 山本大助

Researcher Number	50240106
Other IDs
Affiliation (based on the past Project Information) *help	2007 – 2012: 大阪医科大学, 医学部, 准教授 2010: 大阪医科科大学, 医学部, 准教授 2004 – 2005: 大阪医科大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Functional biochemistry / Laboratory medicine / Digestive surgery / Chemical pharmacy / General physiology
Keywords	Except Principal Investigator catalytic mechanism / energy barrier / amine oxidase / aminotransferase / tunneling / driving force / proton transfer / pyridoxal 5'-phosphate / 触媒反応 / 理論計算 … More / コンフォメーション変化 / 蛋白質 / 触媒反応機構 / エネルギー障壁 / アミン酸化酵素 / アミノ基転移酵素 / トンネル効果 / 駆動力 / プロトン移動 / ピリドキサールリン酸 / アミロイド原性獲得 / 凝集体形成 / 質量イメージング / ラジカル反応 / アミロイド / 手術ビデオ / 外科教科書 / WebSurg Japan / 欧州消化器癌研究所 / 国際交流 / 外科医教育 / インターネット / WebSurg日本版(www.websurg.jp) / 内視鏡外科 / e-learnin / コラーゲン / コアセルベーション / ゲル化 / 結晶化 / CD / βアミノ酸 / 構造活性相関 / ゲーテイング / ATP 加水分解 / Nucleotide Bindin Domain / 二量体化 / アニオン / ゲーティング / ATP加水分解 / Nucleotide Binding Domain / チャネル / CFTR / ABCトランスポータ Less

Investigation of the molecular mechanism of the radical reaction to induce the amyloid fibril derived from the transthyretin
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
外科医教育のためのe-learning用内視鏡外科教材Websurgの充実と発展
- Principal Investigator
  
  谷川允彦
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka Medical College
Development of dosage form using elastin fragments by incorporation of β-amino acids
- Principal Investigator
  
  DOI Mitsunobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Mechanism of Nucleotide Binding Domain engine in ABC transporters
- Principal Investigator
  
  SOHMA Yoshiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Keio University
  Osaka Medical College
Studies on the proton transfer processes in pyridoxal enzymes
- Principal Investigator
  
  HAYASHI Hideyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka Medical College

All 2012 2010 2006 2005

All Journal Article Book

[Book] A critical study of the isosteres of 10^<th> cysteine residue of transthyretin induced with cysteine-S-sulfonate by ultra-high resolutio mass spectrometry. In : Amyloids : Composition, Functions and Pathology(Irene P.Halcheck and Nancy R.Vernon)2012
- Author(s)
  Nakanishi T, Iwasaki N, Saito K, Yoshioka M, Yamamoto D, Tsuji M, Nirasawa T, Takubo T
- Total Pages
  70
- Publisher
  NOVA Science
- Data Source
  KAKENHI-PROJECT-22590540
[Book] A critical study of the isosteres of 10th cysteine residue of transthyretin induced withcysteine-S-sulfonate by ultra-high resolutio mass spectrometry.2012
- Author(s)
  Nakanishi T, Iwasaki N, Saito K, Yoshioka M, Yamamoto D, Tsuji M, Nirasawa T, Takubo T.
- Publisher
  In: Amyloids: Composition, Functions and Pathology. NOVA Publisher (Irene P. Halcheck and Nancy R. Vernon)
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] A critical study of the isosteres of 10th cysteine residue of transthyretin induced with cysteine-S-sulfonate by ultra-high resolutio mass spectrometry.2012
- Author(s)
  Nakanishi T, Iwasaki N, Saito K, Yoshioka M, Yamamoto D, Tsuji M, Nirasawa T, Takubo T.
- Journal Title
  
  In: Amyloids: Composition, Functions and Pathology
  
  Volume: 無し Pages: 165-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.2012
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biochim.Biophys Acta
  
  Volume: 1804 Pages: 1449-1456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.2010
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biochim.Biophys Acta.
  
  Volume: 1804(4) Pages: 1449-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] S-sulfonation of transthyretin is animportant trigger step in the formation of transthyretin-related amyloid fibril. Biochim.2010
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biophys Acta.
  
  Volume: 1804(4) Pages: 1449-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] Quantum mechanical hydrogen tunneling in bacterial copper amine oxidase reaction.2006
- Author(s)
  Murakawa, T., Okajima, T., Kuroda, S., Nakamoto, T., Taki, M., Yamamoto, Y., Hayashi, H., Tanizawa, K.
- Journal Title
  
  Biochem Biophys Res Commun 342
  
  Pages: 414-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570125
[Journal Article] Kinetic and Structural Studies on the Catalytic Role of the Aspartic Acid Residue Conserved in Copper Amine Oxidase.2006
- Author(s)
  Chiu, Y.C., Okajima, T., Murakawa, T., Uchida, M., Taki, M., Hirota, S., Kim, M., Yamaguchi, H., Kawano, Y., Kamiya, N., Kuroda, S., Hayashi, H., Yamamoto, Y., Tanizawa, K.
- Journal Title
  
  Biochemistry 45
  
  Pages: 41055-4120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570125
[Journal Article] L565M mutation in HIV-1 glycoprotein 41 stabilizes the coiled-coil structure.2005
- Author(s)
  Yamamoto, D.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 335(1)
  
  Pages: 112-116
- Data Source
  KAKENHI-PROJECT-16570125

1. SOHMA Yoshiro (60268183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KUBOTA Takahiro (10084906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SOHMIYA Koichi (20319544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. DOI Mitsunobu (10183500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ASANO Akiko (40291801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKANISHI Toyofumi (10247843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. TAKUBO Takayuki (60163359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. TSUJI Motomu (60144466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. NAITO Yasuhide (40237186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAYASHI Hideyuki (00183913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 谷川允彦 (00111956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 奥田準二 (20278518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 林道廣 (90314179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中慶太朗 (40330071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宮本好晴 (20368096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HWANG T.-c

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAMOTO Daisuke 山本 大助

Research Projects

Research Products

Co-Researchers

Investigation of the molecular mechanism of the radical reaction to induce the amyloid fibril derived from the transthyretin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

外科医教育のためのe-learning用内視鏡外科教材Websurgの充実と発展

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of dosage form using elastin fragments by incorporation of β-amino acids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of Nucleotide Binding Domain engine in ABC transporters

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the proton transfer processes in pyridoxal enzymes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] A critical study of the isosteres of 10^<th> cysteine residue of transthyretin induced with cysteine-S-sulfonate by ultra-high resolutio mass spectrometry. In : Amyloids : Composition, Functions and Pathology(Irene P.Halcheck and Nancy R.Vernon)2012

Author(s)

Total Pages

Publisher

Data Source

[Book] A critical study of the isosteres of 10th cysteine residue of transthyretin induced withcysteine-S-sulfonate by ultra-high resolutio mass spectrometry.2012

Author(s)

Publisher

Data Source

[Journal Article] A critical study of the isosteres of 10th cysteine residue of transthyretin induced with cysteine-S-sulfonate by ultra-high resolutio mass spectrometry.2012

Author(s)

Journal Title

Data Source

[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.2012

Author(s)

Journal Title

Data Source

[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.2010

Author(s)

Journal Title

Data Source

[Journal Article] S-sulfonation of transthyretin is animportant trigger step in the formation of transthyretin-related amyloid fibril. Biochim.2010

Author(s)

Journal Title

Data Source

[Journal Article] Quantum mechanical hydrogen tunneling in bacterial copper amine oxidase reaction.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Kinetic and Structural Studies on the Catalytic Role of the Aspartic Acid Residue Conserved in Copper Amine Oxidase.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] L565M mutation in HIV-1 glycoprotein 41 stabilizes the coiled-coil structure.2005

Author(s)

Journal Title

Data Source

YAMAMOTO Daisuke 山本大助