Ikawa Shuntaro 井川俊太郎

… Alternative Names

IKAWA Shuntaro 井川俊太郎

IKAWA Shuntar 井川俊太郎

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Researcher Number	50241576
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2022: 東北大学, 加齢医学研究所, 准教授 2013: 東北大学, 加齢医学研究所, 准教授 2010: 東北大学, 加齢医学研究所, 准教授 2007 – 2009: Tohoku University, 学際科学国際高等研究センター, 准教授 2005 – 2006: 東北大学, 学際科学国際高等研究センター, 助教授 … More 2000 – 2006: Institute of Development, Aging, and Cancer, TOHOKU UNIVERSITY, ASSOCIATE PROFESSOR, 加齢医学研究所, 助教授 1998 – 2000: 東北大学, 加齢医学研究所, 助手 1993 – 1996: 東北大学, 加齢医学研究所, 助手 1992: 東北大学, 抗酸菌病研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Cell biology / Tumor biology / Molecular biology / Human genetics Except Principal Investigator Dermatology / Risk sciences of radiation and chemicals / Hematology / Biological Sciences
Keywords	Principal Investigator 癌抑制遺伝子 / p73 / p53 / p51 / p63 / 転写因子 / アポトーシス / 分化 / 細胞周期 / 遺伝子治療 … More / p53ファミリー遺伝子 / シグナル伝達 / DNA損傷 / NFkB関連遺伝子 / p53関連遺伝子 / がん抑制遺伝子 / 誘導発現 / プロモーター / RB / 発生 / 生殖細胞 / p53ファミリー / miRNA / エストロゲン受容体 / 放射線 / 乳がん / 2）始源生殖細胞 / 幹細胞 / 始源生殖細胞 / 乳癌 / promoter / chimeric gene / gene therapy / tumor suppressor gene / キメラ遺伝子 / cell cycle / inducible expression / differential display / RB gene / tumor suppresser gene / ディファレンシャルディスプレー法 / NFκB関連潰云子 / NFκB関連遺伝子 / NFkB / IKK / ストレス / IKKシグナルソーム / NFκB / 皮膚分化 / ユビキチン化 / Ikkα / 縮重PCR / S変移 / G1 … More Except Principal Investigator p51 / Notch / p53 / 表皮細胞 / Keratinocytes / GATA-1 / 分化 / 乾癬 / シグナル伝達 / p63 / 細胞増殖 / 間質細胞 / 造血幹細胞 / 血液細胞分化 / 転写因子 / 発癌感受性 / P450IIE1 / DNA 損傷 / microRNA / 放射線 / 生物影響 / 始原生殖細胞 / Dermatology / 皮膚 / 皮膚科 / Differentiation / Epithelial cells / 発癌 / 上皮細胞 / transgenic mouse / erythropoiesis / stromal cells / hematopoietic stem cells / hematopoiesis / トランスジェニックマウス / 赤血球分化 / 有棘細胞癌 / 増殖 / 表皮 / Runx / Bach / Perp / Desmoplakin / p51/p63 / デスモプラキン / 細胞死 / 細胞周期 / ポリコーム / 転写制御 / がん抑制遺伝子 / 乳がん / Haplo-insufficiency / ガン抑制遺伝子 / ポリコーム遺伝子群 / 蛋白質複合体 / 発がん / クロマチン / エピジェネティックス / C-myc / 分化決定 / C-Myc / 分化誘導 / MEL細胞 / 血液細胞合化 / YY-1 / c-myc / ヒト臍帯血幹細胞 / MIDA-1 / Id / Arnt / Ahリセプター / 転写活性化ドメイン / ダイマー形成 / PAS蛋白質 / PASドメイン / ダイオキシン / ヒト遺伝子の多型 / P450IA1 / チトクロームP450遺伝子 / ヒト遺伝子のRFLP / チトクローム P-450遺伝子 Less

Normal and tumor suppressive function of p53 family genes and their therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  Ikawa Shuntaro
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
マウス胎児期生殖細胞の放射線応答遺伝子群とmicroRNA群の機能解析
- Principal Investigator
  
  藤村維子
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tohoku University
Transcription factors Runx regulates differentiation and proliferation of keratinocyte
- Principal Investigator
  
  OKUYAMA Ryuhei
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University
Regulation mechanism in keratinocyte growth and differentiation by p53 homologue p51/p63 and Maf
- Principal Investigator
  
  OKUYAMA Ryuhei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tohoku University
Deregulation of Cancer Cell Differentiation and p53 Family GeneSignalinPrincipal Investigator
- Principal Investigator
  
  IKAWA Shuntaro
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
p53 homologue, p51/p63, controls keratinocyte proliferation/differentiation due to Notch activity
- Principal Investigator
  
  OKUYAMA Ryuhei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tohoku University
p53 homolog, p51/p63, maintains keratinocytes under undifferentiated state through suppression of Notch activity.
- Principal Investigator
  
  OKUYAMA Ryuhei
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tohoku University
p53関連遺伝子の細胞周期停止および細胞分化の調節機能Principal Investigator
- Principal Investigator
  
  井川俊太郎
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
転写制御の異常と増殖制御の破綻
- Principal Investigator
  
  菅野雅元
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
癌抑制遺伝子p53の新規類似遺伝子の検索およびクローニングPrincipal Investigator
- Principal Investigator
  
  井川俊太郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku University
血液細胞分化決定を制御する遺伝子の解析
- Principal Investigator
  
  OBINATA Masuo
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
Analyses and Therapeutic Applications of p53 Family Genes, p53, p51, and p73Principal Investigator
- Principal Investigator
  
  IKAWA Shuntaro
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
TITLE OF PROJECT : REGULATION OF ERYTHROPOIETIC DIFFERENTIATION OF IMMORTALIZED HEMATOPOIETIC STEM CELLS
- Principal Investigator
  
  OBINATA Masuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  TOHOKU UNIVERSITY
癌抑制遺伝子p53の新規類似遺伝子p51のクローニングおよび生物学的解析Principal Investigator
- Principal Investigator
  
  井川俊太郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Tohoku University
Ahリセプターの転写因子としての作用と発がん感受性
- Principal Investigator
  
  十川和博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Analysis of cell cycle controlled by Rb tumor suppresser genePrincipal Investigator
- Principal Investigator
  
  IKAWA Shuntar
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
ヒトP450IIE1,IA1の遺伝子多形と癌発生への感受性
- Principal Investigator
  
  渡辺民朗
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
細胞周期における癌抑制遺伝子RB産物の役割Principal Investigator
- Principal Investigator
  
  井川俊太郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
誘導可能なプロモーターを用いた細胞周期の研究Principal Investigator
- Principal Investigator
  
  井川俊太郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
ヒトP450IIE1の遺伝子多型と癌発生への感受性
- Principal Investigator
  
  渡辺民朗
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University

[Book] 癌とシグナル(編修佐竹正延、菅原和夫, シグナル伝達病を知る, p 53)(遺伝子医学MOOK)2006
- Author(s)
  井川俊太郎
- Publisher
  株式会社メディカルドウ
- Data Source
  KAKENHI-PROJECT-17014005
[Book] ファミリーのシグナル伝達による癌抑制のメカニズム(シグナル伝達研究2005-2006, 編修山本雅/仙波憲太郎, p 53)(実験医学)2005
- Author(s)
  井川俊太郎
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Draxin-mediated Regulation of Granule Cell Progenitor Differentiation in the Postnatal Hippocampal Dentate Gyrus.2020
- Author(s)
  Tawarayama H, Yamada H, Amin R, Morita-Fujimura Y, Cooper HM, Shinmyo Y, Tanaka H, Ikawa S.
- Journal Title
  
  Neuroscience
  
  Volume: 431 Pages: 184-192
- DOI
  10.1016/j.neuroscience.2020.02.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19376, KAKENHI-PROJECT-17K07152, KAKENHI-PROJECT-18K09434
[Journal Article] Early BBB breakdown and subacute inflammasome activation and pyroptosis as a result of cerebral venous thrombosis.2018
- Author(s)
  Rashad S, Niizuma K, Sato-Maeda M, Fujimura M, Mansour A, Endo H, Ikawa S, Tominaga T.
- Journal Title
  
  Brain Res.
  
  Volume: 1699 Pages: 54-68
- DOI
  10.1016/j.brainres.2018.06.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07152
[Journal Article] Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis.2018
- Author(s)
  Tawarayama H, Yamada H, Amin R, Morita-Fujimura Y, Cooper HM, Shinmyo Y, Kawata M, Ikawa S, Tanaka H.
- Journal Title
  
  Sci Rep.
  
  Volume: 8(1) Issue: 1 Pages: 840-840
- DOI
  10.1038/s41598-018-19346-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06733, KAKENHI-PROJECT-17K07152
[Journal Article] The chemorepellent draxin is involved in hippocampal mossy fiber projection.2018
- Author(s)
  Tawarayama H, Yamada H, Shinmyo Y, Tanaka H, Ikawa S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 500 Issue: 2 Pages: 217-223
- DOI
  10.1016/j.bbrc.2018.04.043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07152, KAKENHI-PROJECT-18K09434, KAKENHI-PROJECT-18K19376, KAKENHI-PROJECT-16H04654
[Journal Article] Transient Global Cerebral Ischemia Induces RNF213, a Moyamoya Disease Susceptibility Gene, in Vulnerable Neurons of the Rat Hippocampus CA1 Subregion and Ischemic Cortex.2017
- Author(s)
  Sato-Maeda M, Fujimura M, Rashad S, Morita-Fujimura Y, Niizuma K, Sakata H, Ikawa S, Tominaga T.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: 26 Issue: 9 Pages: 1904-1911
- DOI
  10.1016/j.jstrokecerebrovasdis.2017.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07152, KAKENHI-PROJECT-17K10815
[Journal Article] Opposing functions of Fbxw7 in keratinocyte growth-differentiation and skin tumorigesis mediated through negative regulation of c-Myc and Notch2013
- Author(s)
  Ishikawa Y, Hosogane M, Okuyama R, Aoyama S, Onoyama I, Nakayama K, Nakayama K
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 15 Pages: 1921-1932
- DOI
  10.1038/onc.2012.213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591615
[Journal Article] Epidermal FABP (FABP5) regulates keratinocyte differentiation via 13(S)-HODE-mediated activation of the NF-κB signaling pathway2011
- Author(s)
  Ogawa E, Owada Y, Ikawa S, Adachi Y, Egawa T, Nemoto K, Suzuki K, Hishinuma T, Kawashima H, Kondo H, Muto M, Aiba S, Okuyama R
- Journal Title
  
  J Invest Dermatol
  
  Volume: 131 Pages: 604-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591615
[Journal Article] Epidermal FABP (FABP5) regulates keratinocyte differentiation via 13(S)-HODE-mediated activation of the NF-kB signaling pathway.2011
- Author(s)
  Ogawa E, Owada Y, Ikawa S, Adachi Y, Egawa T, Nemoto K, Suzuki K, Hishinuma T, Kawashima H, Kondo H, Muto M, Aiba S, Okuyama R.
- Journal Title
  
  J Invest Dermatol 131
  
  Pages: 604-612
- Data Source
  KAKENHI-PROJECT-20591314
[Journal Article] Calchiphylaxis with POEMS syndrome2011
- Author(s)
  Yoshikawa M, Uhara H, Arakura F, Murata H, Kubo H, Takata M, Yoshida K, Okuyama R
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 91 Issue: 1 Pages: 98-99
- DOI
  10.2340/00015555-0968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591615
[Journal Article] Expression analysis of p51/p63 in enamel organ epithelial cells2010
- Author(s)
  Matsuura T., Nagoshi H., Tomooka Y., Ikawa S., Sasaki K.
- Journal Title
  
  Interface oral health science 2009 36
  
  Pages: 133-136
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Expression analysis of p51/p63 in enamel organ epithelial cells2010
- Author(s)
  Matsuura T., Nagoshi H., Tomooka Y., Ikawa S., Sasaki K.
- Journal Title
  
  Interface oral health scienoe 2009
  
  Pages: 133-136
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes2010
- Author(s)
  Okada, S., Muto, A., Ogawa, E., Nakanome, A., Katoh, Y., Ikawa, S., Aiba, S., Igarashi, K., Okuyama, R.
- Journal Title
  
  Journal of Biological Chemistry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes.2010
- Author(s)
  Okada S, Muto A, Ogawa E, Nakanome A, Katoh Y, Ikawa S, Aiba S, Igarashi K, Okuyama R.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 23581-23589
- Data Source
  KAKENHI-PROJECT-20591314
[Journal Article] Bach1-dependent and-independent regulation of heme oxygenase 1 in keratinocytes.2010
- Author(s)
  Okada S, Muto A, Ogawa E, Nakanome A, Katoh Y, Ikawa S, Aiba S, Igarashi K, Okuyama R.
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 23581-23589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591314
[Journal Article] Ectopic expression of the p53 homologue p63 is linked to squamous metaplasia in extramammary Paget's disease with invasive adenocarcinoma2009
- Author(s)
  Okuyama R, Ogawa E, Egawa T, Nagoshi H, Tagami H, Ikawa S, Aiba S.
- Journal Title
  
  Histopahology 54(2009)
  
  Pages: 378-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Ectopic expression of the p53 homologue p63 is linked to squamous metaplasia in extramammary Paget's disease with invasive adenocarcinoma2009
- Author(s)
  Ogawa E, Okuyama R, Egawa T, Nagoshi H, Tagami H, Ikawa S, Aiba S.
- Journal Title
  
  Histopathology 54
  
  Pages: 378-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Ectopic expression of the p53 homologue p63 is linked to squamous metaplasia in extramammary Paget's disease with invasive adenocarcinoma.2009
- Author(s)
  Okuyama R, Ogawa E, Egawa T, Nagoshi H, Tagami H, Ikawa S, Aiba S.
- Journal Title
  
  Histopahology 54
  
  Pages: 378-381
- Data Source
  KAKENHI-PROJECT-20591314
[Journal Article] Expression analysis of p51/p63 in enamel organ epithelial cells2009
- Author(s)
  Matsuura T., Nagoshi H., Tomooka Y., Ikawa S., Sasaki K.
- Journal Title
  
  Journal of oral biosciences 36
  
  Pages: 51-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Ectopic expression of the p53 homologue p63 is linked to squamous metaplasia in extramammary Paget's disease with invasive adenocarcinoma2009
- Author(s)
  Ogawa E, Okuyama R, Egawa T, Nagoshi H, Tagami H, Ikawa S, Aiba S
- Journal Title
  
  Histopathology 54
  
  Pages: 378-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Expression analysis of p51/p63 in enamel organ epithelial cells2009
- Author(s)
  Matsuura T., Nagoshi H., Tomooka Y., Ikawa S., Sasaki K.
- Journal Title
  
  Journal of Oral Biosciences 36
  
  Pages: 51-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p51/p63 inhibits ultraviolet B-induced apoptosis via Akt activation.2008
- Author(s)
  Okuyama R, Ogawa E, Ikawa S, Nagoshi H, Egawa T, Kurihara A, Yabuki M, Tagami H, Obinata M, Aiba S.
- Journal Title
  
  Oncogene 27
  
  Pages: 848-856
- Data Source
  KAKENHI-PROJECT-20591314
[Journal Article] p51/p63 Inhibits ultraviolet B-induced apoptosis via Akt activation2008
- Author(s)
  Ogawa E, Okuyama R, Ikawa S, Nagoshi H, Egawa T, Kurihara A, Yabuki M, Tagami H, Obinata M, Aiba S
- Journal Title
  
  Oncogene 27
  
  Pages: 848-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article]2008
- Author(s)
  Okuyama R, Ogawa E, Egawa T, Nagoshi H, Obinata M, Tagami H, Ikawa S, Aiba S.
- Journal Title
  
  Journal of Biological Chemistry 283(2008)
  
  Pages: 34241-34249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article]2008
- Author(s)
  Okuyama R, Ogawa E, Ikawa S, Nagoshi H, Egawa T, Kurihara A, Yabuki M, Tagami H, Obinata M, Aiba S.
- Journal Title
  
  Oncogene 27
  
  Pages: 848-856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p63-induced onset of keratinocyte differentiation via the c-Jun-N terminal kinase pathway is counteracted by keratinocyte growth factor.2008
- Author(s)
  Okuyama R, Ogawa E, Egawa T, Nagoshi H, Obinata M, Tagami H, Ikawa S, Aiba S.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 34241-34249
- Data Source
  KAKENHI-PROJECT-20591314
[Journal Article] p51/p63 inhibits ultraviolet B-induced apoptosis via Akt activation.2008
- Author(s)
  Ogawa, E, Okuyama, R., Ikawa, S., Nagoshi, H., Egawa, T., Kurihara, A., Yabuki, M., Tagami, H., Obinata, M., and, Aiba, S.
- Journal Title
  
  Oncogene (accepted). (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor2008
- Author(s)
  Ogawa E, Okuyama R, Egawa T, Na goshi H, Obinata M, Tagami H, Ikawa S, Aiba S
- Journal Title
  
  J Biol Chem 283
  
  Pages: 34241-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Ser46 phosphorylation of p53 is not always sufficient to induce apoptosis: multiple mechanisms of regulation of p53-dependent apoptosis.2007
- Author(s)
  Kurihara A, Nagoshi H, Yabuki M, Okuyama R, Obinata M, Ikawa S.
- Journal Title
  
  Genes Cells 12(7)
  
  Pages: 853-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity2007
- Author(s)
  Okuyama, R., Ogawa, E., Nagoshi, H., Yabuki, M., Kurihara, A., Terui, T., Aiba, S., Obinata, M., Tagami, H., Ikawa, S.
- Journal Title
  
  Oncogene 26
  
  Pages: 4478-4488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity.2007
- Author(s)
  Okuyama R, Ogawa E, Nagoshi H, Yabuki M, Kurihara A Terui T, Aiba S, Obinata M, Tagami H, Ikawa S.
- Journal Title
  
  Oncogene 5;26(31)
  
  Pages: 4478-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p53 Homologue, p51/p63, Maintains the Immaturity of Keratinocyte Stem Cells by Inhibiting Notch1 Activity.2007
- Author(s)
  Okuyama R, Ogawa E, Nagoshi H, Yabuki M, Kurihara A, Terui T, Aiba S, Obinata M, Tagami H, Ikawa S.
- Journal Title
  
  Oncogene (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591154
[Journal Article] Ser46 phosphorylation of p53 is not always sufficient to induce apoptosis: multiple mechanisms of regulation of p53-dependent apoptosis2007
- Author(s)
  Kurihara, A., Nagoshi, A., Yabuki, M., Okuyama, R., Obinata, M., Ikawa, S.
- Journal Title
  
  Genes Cells 12
  
  Pages: 853-861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p51/p63, a novel p53 homologue, potentiates p53 activity and is a human cancer gene therapy candidate2006
- Author(s)
  Kunisaki, R., Ikawa, S., Maeda, R., Nakazaki, Y., Kurita, R., Harata, M., Shutoh, Y., Bai, S.Y., Tanabe, T., Dohi, T., Kato, R., Ikawa, Y., Sekihara, H., Asano, S., Tani, K
- Journal Title
  
  J Gene Med 8
  
  Pages: 1120-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p51/p63, a novel p53 homologue, potentiates p53 activity and is a human cancer gene therapy candidate.2006
- Author(s)
  Kunisaki, R., Ikawa, S., Maeda, R., Nakazaki, Y., Kurita, R., Harata, M., Shutoh, Y., Bai, S.Y., Tanabe, T., Dohi, T., Kato, R., Ikawa, Y., Sekihara, H., Asano, S., Tani, K.
- Journal Title
  
  J Gene Med. 8
  
  Pages: 1120-1130
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] p51/p63, a novel p53 homologue, potentates p53 activity and is a human cancer gene therapy candidate.2006
- Author(s)
  Kunisaki R, Ikawa S, Maeda T, Nakazaki Y, Kurita R.Harata M, Shutoh Y, Bai YS, Soda Y, Tanabe T, Dobi T, Kato R, Ikawa Y, Asano S, Tani K.
- Journal Title
  
  j Gene Med 8
  
  Pages: 1121-1130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591154
[Journal Article] Stimulation of Dmc1-mediated DNA strand exchange by the human Rad54B protein.2006
- Author(s)
  Sarai N, Kagawa W, Kinebuchi T, Kagawa A, Tanaka K, Miyagawa K, Ikawa S, Shibata T, Kurumizaki H, Yokoyama S.
- Journal Title
  
  Nucleic Acids Res 34
  
  Pages: 4429-4437
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591154
[Journal Article] Identification and characterization of Xenopus laevis homologs of mammalian TRAF6 and its binding protein TIFA.2005
- Author(s)
  Inoue, JI., Yagi, S., Ishikawa, K., Azuma, S., Ikawa.S., Semba, K
- Journal Title
  
  Gene 358
  
  Pages: 53-59
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Structure and the evolutionary implication of the triplicated complement factor B genes of a urochordate ascidian, Ciona intestinalis2005
- Author(s)
  Yoshizaki, FY., Ikawa, S., Satake, M., Satoh, N., Nonaka, M.
- Journal Title
  
  Immunogenetics. Immunogenetics 56
  
  Pages: 930-942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Identification and characterization of Xenopus laevis homologs of mammalian TRAF6 and its binding protein TIFA2005
- Author(s)
  Inoue, JI., Yagi, S., Ishikawa, K., Azuma, S., Ikawa, S., Semba, K.
- Journal Title
  
  Gene 358
  
  Pages: 53-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Identification of DRG family regulatory proteins (DFRPs): specific regulation of DRG1 and DRG2.2005
- Author(s)
  Ishikawa, K., Azuma, S., Ikawa, S., Semba, K., Inoue, J.
- Journal Title
  
  Genes Cells. 10
  
  Pages: 139-150
- Data Source
  KAKENHI-PROJECT-13216006
[Journal Article] Structure and the evolutionary implication of the tripicated complement factor B genes of a urochordate ascidian, Ciona intestinalis.2005
- Author(s)
  Yoshizaki, FY., Ikawa S., Satake, M., Satoh, N., Nonaka, M
- Journal Title
  
  Immunogenetics 56
  
  Pages: 930-942
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Identification of DRG family regulatory proteins (DFRPs) : specific regulation of DRG1 and DRG2.2005
- Author(s)
  Ishikawa, K., Azuma, S., Ikawa S., Semba, K., Inoue, J
- Journal Title
  
  Genes Cells 10
  
  Pages: 139-150
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Identification of DRG family regulatory proteins (DFRPs): specific regulation of DRG1 and DRG22005
- Author(s)
  Ishikawa, K., Azuma, S., Ikawa, S., Semba, K., Inoue, J.
- Journal Title
  
  Genes Cells 10
  
  Pages: 139-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Reporter gene stimulation by MIDA1 through its DnaJ homology region.2004
- Author(s)
  Yoshida, M, Inoue, T, Shoji W, Ikawa S, Obinata, M.
- Journal Title
  
  Biochem Biophys Res Commun 324
  
  Pages: 326-332
- Data Source
  KAKENHI-PROJECT-13216006
[Journal Article] TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain.2004
- Author(s)
  Matsumura, T., Semba, K., Azuma, S., Ikawa, S., Gohda, J., Akiyama, T., Inoue, J
- Journal Title
  
  Biochem.Biophys.Res.Comm. 317
  
  Pages: 230-234
- Data Source
  KAKENHI-PROJECT-13216006
[Journal Article] p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notchl activity.
- Author(s)
  Okuyama, R., Ogawa, E., Nagoshi, H., Yabuki, M., Kurihara, A., Terui, T., Aiba, S., Obinata, M., Tagami, H., Ikawa, S.
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Ser46 phosphorylation of p53 is not always sufficient to induce apoptosis : multiple mechanisms of regulation of p53-dependent apoptosis.
- Author(s)
  Kurihara, A., Nagoshi, A., Yabuki, M., Okuyama, R., Obinata, M., Ikawa, S.
- Journal Title
  
  Genes Cell (in press)
- Data Source
  KAKENHI-PROJECT-17014005
[Journal Article] Structure and the evolutionary implication of the triplicated complement factor B genes of a urochordate ascidian, Ciona intestinalis.
- Author(s)
  Yoshizaki, FY., Ikawa, S., Satake, M., Satoh.N., Nonaka, M.
- Journal Title
  
  Immunogenetics. (In press.)
- Data Source
  KAKENHI-PROJECT-13216006
[Patent] p53 ファミリーのキメラ遺伝子及びキメラタンパク2009
- Inventor(s)
  井川洋二、井川俊太郎、帯刀益夫
- Industrial Property Rights Holder
  井川洋二、大塚製薬株式会社
- Filing Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-17014005
[Patent] p53ファミリーのキメラ遺伝子及びキメラタンパク2009
- Inventor(s)
  井川洋二、井川俊太郎、帯刀益夫
- Industrial Property Rights Holder
  井川洋二、大塚製薬株式会社
- Acquisition Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] マウス胎児期生殖細胞の放射線応答遺伝子群とmicroRNA群の同定2016
- Author(s)
  藤村維子、アミンルフル、俵山寛司、前田郁麻、松居靖久、井川俊太郎
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K00539
[Presentation] A regulation of keratinocyte differentiation and proliferation by transcription factors Runx1 and Runx32013
- Author(s)
  Uchiyama R, Ogawa E, Kiniwa Y, Uhara H, Wong WF, Kofu K, Ikawa S, Satake M, Okuyama R
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-23591615
[Presentation] A regulation of keratinocyte differentiation and proliferation by transcription factors Runx1 and Runx32013
- Author(s)
  Uchiyama R, Ogawa E, Kiniwa Y, Uhara H, Wong WF, Kofu K, Ikawa S, Satake M, Okuyama R
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-23591615
[Presentation] Transcription factors Runx1 and Runx3 regulate differentiation and proliferation of keratinocyte2012
- Author(s)
  Uchiyama R, Ogawa E, Kiniwa Y, Uhara H, Wong WF, Kofu K, Ikawa S, Satake M, Okuyama R
- Organizer
  日本研究皮膚科学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23591615
[Presentation] 歯胚発生におけるp51/p63遺伝子の役割2009
- Author(s)
  松裏貴史, 名越弘和, 友岡康弘, 井川俊太郎, 佐々木啓一
- Organizer
  第51回歯科基礎医学会
- Place of Presentation
  新潟
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] Notch2 down-regulation in wound healing is contributed to acceleration of cell motility.2009
- Author(s)
  Okuyama R, Saito R, Ogawa E, Ikawa S, Aiba S.
- Organizer
  日本研究皮膚科学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20591314
[Presentation] Notch2 down-regulation in wound healing is contributed to acceleration of cerll motility2009
- Author(s)
  斉藤るみ子、奥山隆平、小川英作、井川俊太郎、饗庭節也
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] p63 prevents growth arrest via sonic hedgehog induction.2009
- Author(s)
  Ogawa E, Okuyama R, Okada S, Ikawa S, Aiba S.
- Organizer
  日本研究皮膚科学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20591314
[Presentation] 骨格筋分化におけるp53類似遺伝子p51の役割2009
- Author(s)
  小川静香、井川俊太郎、永富良一
- Organizer
  第64回日本体力医学会大会
- Place of Presentation
  新潟
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] Cell fate determination by IkB kinase g-p51 ubiquitin ligase-p51 pathway in Response to DNA damaging Stimuli.2007
- Author(s)
  Nagoshi, H., Ikawa. S.
- Organizer
  98th annual meeting of American Association for Cancer Research.
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] Cell Fate Determination by IKK gamma-p53 family pathway in Response to DNA Damaging Stimuli.2007
- Author(s)
  名越弘和、栗原祥、矢吹仁人、帯刀益夫、井川俊太郎
- Organizer
  第66回日本癌学会総会一般口演
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] 98th annual meeting of American Association for Cancer Research2007
- Author(s)
  Nagoshi, H., Ikawa, S.
- Organizer
  97th annual meeting of American Association for Cancer Research (mini symposium, Ito-en young investigator award)
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] The p53 family gene chimeras: a new resource for potent gene therapy of cancer2006
- Author(s)
  Yabuki, M., Kaneshiro, K., Nagoshi, H., Kurihara, A., Aburatani, H., Obinata, M., Ikawa, S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japa
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] Regulation of Apoptosis by IkB kinase g -p51 ubiquitin ligase - p51pathway in Response to DNA damaging Stimuli2006
- Author(s)
  Nagosh, H., Ikawa, S.
- Organizer
  97th annual meeting of American Association for Cancer Research (mini symposium, Ito-en young investigator award)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-17014005
[Presentation] Mechanisms of Cell Fate Determination in Response to DNA Damage by p53 Family Proteins2006
- Author(s)
  Kurihara, A., Nagoshi, H., Yabuki, M., Obinata, M., Ikawa, S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17014005
[]

1. OKUYAMA Ryuhei (80292332)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. OBINATA Masuo (10099971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YANAI Nobuaki (80200525)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 渡辺民朗 (40006101)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 阿部達也 (70222651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 金丸龍之介 (70152783)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OGAWA EISAKU (20451586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. SATAKE Masanobu (50178688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 十川和博 (80175421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 藤井義明 (00098146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 菊地康夫 (10004467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 東海林互 (40250831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 菅野雅元 (40161393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 二宮裕一 (70334175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤村維子 (80291087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 桑原義和 (00392225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 俵山寛司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 新明洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ikawa Shuntaro 井川 俊太郎

IKAWA Shuntaro 井川 俊太郎

IKAWA Shuntar 井川 俊太郎

Research Projects

Research Products

Co-Researchers

Normal and tumor suppressive function of p53 family genes and their therapeutic applicationPrincipal Investigator

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Deregulation of Cancer Cell Differentiation and p53 Family GeneSignalinPrincipal Investigator

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p53関連遺伝子の細胞周期停止および細胞分化の調節機能Principal Investigator

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癌抑制遺伝子p53の新規類似遺伝子の検索およびクローニングPrincipal Investigator

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Analyses and Therapeutic Applications of p53 Family Genes, p53, p51, and p73Principal Investigator

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癌抑制遺伝子p53の新規類似遺伝子p51のクローニングおよび生物学的解析Principal Investigator

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Ikawa Shuntaro 井川俊太郎

IKAWA Shuntaro 井川俊太郎

IKAWA Shuntar 井川俊太郎

[Book] 癌とシグナル(編修佐竹正延、菅原和夫, シグナル伝達病を知る, p 53)(遺伝子医学MOOK)2006

[Book] ファミリーのシグナル伝達による癌抑制のメカニズム(シグナル伝達研究2005-2006, 編修山本雅/仙波憲太郎, p 53)(実験医学)2005