Masutani Hiroshi 増谷弘

… Alternative Names

Masutani HIroshi 増谷弘

MASUTANI Hiroshi 増谷弘

増谷弘マスタニヒロシ

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Researcher Number	50252523
Other IDs
External Links
Affiliation (Current)	2025: 天理大学, 医療学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 天理医療大学, 医療学部, 教授 2011 – 2015: 京都大学, ウイルス研究所, 准教授 2008 – 2009: Kyoto University, ウイルス研究所, 准教授 2003 – 2006: 京都大学, ウイルス研究所, 助教授 2001 – 2002: 京都大学, ウイルス研究所, 助手 1997 – 1999: 京都大学, ウイルス研究所, 助手 1998: INSTITUTE FOR VIRUS RESEARCH,KYOTO UNIVERSITY, ASSISTANT PROFESSOR, ウィルス研究所, 助手
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Pathological medical chemistry / Basic Section 49010:Pathological biochemistry-related / Biological Sciences / Biological Sciences Except Principal Investigator Experimental pathology / General medical chemistry / Digestive surgery / General surgery / Biological Sciences
Keywords	Principal Investigator Nrf2 / thioredoxin / Txnip / 癌 / 糖尿病 / アルファアレスチン / 酸化ストレス / lncRNA / RNA / NGF … More / CRE / ARE / シグナル伝達 / ヘミン / 転写因子 / p53 / プロモーター / ダイオキシン / アポトーシス / 低分子化合物 / インスリン抵抗性 / TBP-2 / トリプルネガティブ / リボヌクレオプロテイン複合体 / オートファジー / 層別診断法 / 乳癌 / Autophagy / triple negative / breast cancer / CDK5 / リボヌクレオプロテイン / 代謝 / 神経保護作用 / αアレスチン / Tau / アルツハイマー / プロテオミクス / アレスチン / long non coding RNA / 高分子複合体 / アルツハイマー病 / signal transduction / promoter / Oxidative stress / 神経突起伸長 / NFG / 3-methylcholanthrene / CANCER / PROMOTER / DIOXIN / APOPTOSIS / THIOREDOXIN / OXIDATIVE STRESS / 低分子化合物スクリーニング / 化合物スクリーニング / イノベーション / 癌抑制 / 創薬 / ケミカルバイオロジー / スクリーニング / 脂肪細胞分化 / 筋肉 / 脂肪蓄積制御 / エネルギー代謝制御 / TBP-2/Txnip / oxidative stress / cell cycle / metabolism / cancer / thioredoxin 2 / arrestin / cyclin D1 / apoptosis / redox / thioredoxin 2 (TRX2) / thioredoxin binding protein-2 (TBP-2) / thioredoxin (TRX) … More Except Principal Investigator チオレドキシン / thioredoxin / レドックス / redox / 抗癌剤 / レドックス制御 / modified protein / lipid rafts / redox regulation / レドックス(酸化還元) / ストレスシグナル / 改変体 / リピッドラフト / tumor growth / recombinant protein / anti-cancer drug / tumor / 遺伝子組み換え蛋白質 / 腫瘍増殖 / 遺伝子組換え蛋白質 / 固形腫瘍 / metabolic syndrome / vitamin D / Reye syndrome / cancer / aging / thioredoxin binding protein 2 / チオレドキシン結合タンパク質 / 遺伝子改変マウス / 細胞増殖 / シオレドキシン結合タンパク質 / 絶食 / 高脂血症 / 癌抑制 / 糖脂質代謝 / メタボリックシンドローム / ビタミンD / ライ症候群 / 癌 / 老化 / レドツクス / TBP-2 / Biological response / Apoptosis / Surgical stresses / Redox regulation / Thioredoxin / Glutathione / 生体応答 / アポトーシス / 外科的ストレス / チオレドキン / グルタチオン / 膵島 / 細胞・組織 / 糖尿病 / 移植・再生医療 / ストレス / 生体防御 / 感染 / トランスジェニックマウス / ウイルス / プロテオーム Less

Development of stratified diagnostic method of breast cancer and elucidation of the regulatory mechanism of RNA based on Txnip researchPrincipal Investigator
- Principal Investigator
  
  Masutani Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tenri Health Care University
Metabolic regulation and cancer suppression by Thioredoxin interacting protein (Txnip) ribonucleoprotein complexPrincipal Investigator
- Principal Investigator
  
  Masutani HIroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tenri Health Care University
Elucidation of the molecular mechanism of insulin resistance by investigating TBP-2/Txnip and chemical biologyPrincipal Investigator
- Principal Investigator
  
  MASUTANI Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
アルファアレスチンによる絶食応答・脂肪蓄積制御Principal Investigator
- Principal Investigator
  
  増谷弘
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Establishment of a next generation cell therapy for diabetes based on Thioredoxin and C5a inhibitory peptide
- Principal Investigator
  
  GOTO Masafumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
レドックス制御分子による癌細胞の増殖・死の調節機構の研究Principal Investigator
- Principal Investigator
  
  増谷弘
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Analysis of the mechanism and biological function of the internalization of thioredoxin into cells via lipid raft.
- Principal Investigator
  
  YODOI Junji, 近藤則彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Effect of oxidative stress and redox-regulating proteins on tumor growth and chemosensitivity
- Principal Investigator
  
  UEDA Shugo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The Tazuke Kofukai Medical Reserch Institute
  Kyoto University
The study on the regulation of cellular growth and aging process by thioredoxin binding protein
- Principal Investigator
  
  YODOI Junji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
チオレドキシンシステムのプロテオーム解析による感染宿主応答分子機構の研究
- Principal Investigator
  
  NAKAMURA Hajime
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Investigation of biological function of thioredoxin by construction of thioredoxin knock down micePrincipal Investigator
- Principal Investigator
  
  MASUTANI Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
ANALYSIS OF OXIDATIVE STRESS INDUCED APOPTOSIS MECHANISM AND THE BINDING PROTEINS TO THE OXIDATIVE RESPONSIVE ELEMENTPrincipal Investigator
- Principal Investigator
  
  MASUTANI Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
ANALYSIS AND ITS CLINICAL APPLICATION OF REDOX REGULATION MECHANISM FOR SURGICAL STRESS
- Principal Investigator
  
  TAKABAYASHI Arimichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tazuke Kofukai Medical Institute

[Book] 酸化ストレスの医学2014
- Author(s)
  増谷　弘
- Total Pages
  10
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25460386
[Journal Article] Thioredoxin-Interacting Protein in Cancer and Diabetes.2021
- Author(s)
  Hiroshi Masutani
- Journal Title
  
  Antioxid Redox Signal.
  
  Volume: - Issue: 13-15 Pages: 311-316
- DOI
  10.1089/ars.2021.0038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07347
[Journal Article] TXNIP induces growth arrest and enhances ABT263-induced apoptosis in mixed-lineage leukemia-rearranged acute myeloid leukemia cells.2020
- Author(s)
  Mina Noura, Hidemasa Matsuo, Asami Koyama, Souichi Adachi, Hiroshi Masutani.
- Journal Title
  
  FEBS openbio
  
  Volume: 10 Issue: 8 Pages: 1532-1541
- DOI
  10.1002/2211-5463.12908
- NAID
  120006879474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07347, KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19K17875
[Journal Article] IL-2/IL-2 Receptor Pathway Plays a Crucial Role in the Growth and Malignant Transformation of HTLV-1-Infected T Cells to Develop Adult T-Cell Leukemia.2020
- Author(s)
  Maeda M, Tanabe-Shibuya J, Miyazato P, Masutani H, Yasunaga JI, Usami K, Shimizu A, Matsuoka M.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 11 Pages: 356-356
- DOI
  10.3389/fmicb.2020.00356
- NAID
  120006936325
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07166, KAKENHI-PROJECT-17K08658, KAKENHI-PROJECT-17K19610, KAKENHI-PROJECT-16H05336, KAKENHI-PROJECT-19H03689
[Journal Article] Metabolic regulation of Thioredoxin interacting protein (Txnip)-containing high molecular protein complexes2020
- Author(s)
  Cristiane Lumi Hirata, Kanari Nishioka, Sae Ashida, Yoichi Mizutani, Hiroshi Masutani
- Journal Title
  
  Bulletin of Tenri Health Care University
  
  Volume: 8 Pages: 16-16
- NAID
  130007903379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08658
[Journal Article] Thioredoxin as a novel sensitive marker of biological stress response in smoking2020
- Author(s)
  Soyama Tomonori、Masutani Hiroshi、Lumi Hirata Cristiane、Iwai-Kanai Eri、Inamoto Takashi
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 67 Issue: 3 Pages: 228-231
- DOI
  10.3164/jcbn.19-108
- NAID
  130007934181
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08609, KAKENHI-PROJECT-20K07347, KAKENHI-PROJECT-19K18196
[Journal Article] Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.2019
- Author(s)
  Hirata CL, Ito S, Masutani H
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 677 Pages: 108159-108159
- DOI
  10.1016/j.abb.2019.108159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08658
[Journal Article] Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes.2019
- Author(s)
  Hirata CL, Ito S, Masutani H
- Journal Title
  
  Data Brief
  
  Volume: 28 Pages: 104893-104893
- DOI
  10.1016/j.dib.2019.104893
- NAID
  120006784424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08658
[Journal Article] 癌・病態におけるThioredoxin、Txnip、ARRDC3研究の最近の展開2018
- Author(s)
  増谷　弘、Cristiane Lumi HIRATA
- Journal Title
  
  天理医療大学紀要
  
  Volume: 印刷中
- NAID
  130007674666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08658
[Journal Article] 癌・病態におけるThioredoxin, Txnip, ARRDC3研究の最近の展開2018
- Author(s)
  増谷　弘、Cristiane Lumi HIRATA
- Journal Title
  
  天理医療大学紀要
  
  Volume: 6 Pages: 14-20
- NAID
  130007674666
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08658
[Journal Article] Anti-Inflammatory Thioredoxin Family Proteins for Medicare, Healthcare and Aging Care2017
- Author(s)
  Yodoi Junji, Matsuo Yoshiyuki, Tian Hai, Masutani Hiroshi, Inamoto Takashi
- Journal Title
  
  Nutrients
  
  Volume: 9 Issue: 10 Pages: 1081-1081
- DOI
  10.3390/nu9101081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10975, KAKENHI-PROJECT-17K08658
[Journal Article] Establishment of a Therapeutic Anti-Pan HLA-Class II Monoclonal Antibody That Directly Induces Lymphoma Cell Death via Large Pore Formation.2016
- Author(s)
  Matsuoka S, Ishii Y, Nakao A, Abe M, Ohtsuji N, Momose S, Jin H, Arase H, Sugimoto K, Nakauchi Y, Masutani H, Maeda M, Yagita H, Komatsu N, Hino O
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 3 Pages: e0150496-e0150496
- DOI
  10.1371/journal.pone.0150496
- NAID
  120005838168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-25460386, KAKENHI-PROJECT-26670475, KAKENHI-PROJECT-15H02545, KAKENHI-PROJECT-15F15115, KAKENHI-PROJECT-26290059
[Journal Article] A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS2015
- Author(s)
  Nagano S, Takahashi Y, Yamamoto K, Masutani H, Fujiwara N, Urushitani M, Araki T
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 0n line Issue: 12 Pages: 1-13
- DOI
  10.1093/hmg/ddv093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460386, KAKENHI-PROJECT-26290023, KAKENHI-PROJECT-25461302
[Journal Article] 酸化ストレスシグナルと酸化ストレス防御2015
- Author(s)
  増谷　弘
- Journal Title
  
  別冊医学のあゆみ、レドックスUPDATE
  
  Volume: 1 Pages: 10-14
- Data Source
  KAKENHI-PROJECT-25460386
[Journal Article] Protective effects of oral administration of yeast thioredoxin against gastric mucosal injury2014
- Author(s)
  Taketani, Y., Kinugasa, K., Kitajima, R., Nishiumi, S., Ashida, H., Nakamura, H., Fujita, T., Kanzaki, K., Masutani, H., Yodoi, J
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 78 Pages: 1221-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460386
[Journal Article] Thioredoxin-1 attenuates early graft loss after intraportal islet transplantation in mice2013
- Author(s)
  Asami K, Inagaki A, Imura T, Sekiguchi S, Fujimori K, Masutani H, Y odoi J, Satomi S, Ohuchi N, Got o M
- Journal Title
  
  PLOS ONE
  
  Volume: 8(8) Issue: 8 Pages: e70259-e70259
- DOI
  10.1371/journal.pone.0070259
- NAID
  130005548951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390310, KAKENHI-PROJECT-25460386
[Journal Article] Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization2013
- Author(s)
  Ogata FT, Batista WL, Sartori A, Gesteira TF, Masut ani H, Arai RJ, Y odoi J, Stern A, Monteiro HP
- Journal Title
  
  PLOS ONE
  
  Volume: 8(12) Issue: 12 Pages: e84588-e84588
- DOI
  10.1371/journal.pone.0084588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390310, KAKENHI-PROJECT-25460386
[Journal Article] アルファアレスチンファミリー欠損マウスの解析から判明したエネルギー代謝調節機構と肥満・糖尿病の新たな治療法開発TBP-2: 糖尿病の悪化に関与するキー分子 (review).2012
- Author(s)
  増谷弘
- Journal Title
  
  遺伝子MOOK
  
  Volume: 22 Pages: 147-152
- Data Source
  KAKENHI-PUBLICLY-23126512
[Journal Article] Thioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus2011
- Author(s)
  Masutani, H., Yoshihara, E., Masaki, S., Chen, Z., Yodoi, J
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 50 Issue: 1 Pages: 23-34
- DOI
  10.3164/jcbn.11-36SR
- NAID
  130004466667
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23126512
[Journal Article] Thioredoxin Binding Protein-2 (TBP-2)/ Txnip is a Criticat Regulator of Insulin Secretion and PPAR Function2009
- Author(s)
  Oka S, Yoshihara E, Bizen-Abe A, Liu W, Watanabe M, Yodoi J, and Masutani H.
- Journal Title
  
  Endocrinology 150
  
  Pages: 1225-1234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013019
[Journal Article] Fragrant Unsaturated Aldehydes Elicit Activation of the Keapl/ Nrf2 System Leading to the Up-regulation Of Thioredoxin Expression and Protection against Oxidative Stress2009
- Author(s)
  Masutani H, Otsuki R, Yamaguchi Y, Takenaka M, Kanoh N, Takatera K, Kunimoto
- Journal Title
  
  Antioxid Redox Signal
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013019
[Journal Article] Fragrant unsaturated aldehydes elicit activation of the Keapl/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress.2009
- Author(s)
  Masutani H, et al.
- Journal Title
  
  Antioxid Redox Signal 11
  
  Pages: 949-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013019
[Journal Article] Thioredoxin-1 promotes survival of cells exposed to S-nitrbsoglutathione : Correlation with reduction of intracellular levels of nitrosothiols and up-regulation of the ERK1/2 MAP Kinases2008
- Author(s)
  Arai RJ, Ogata FT, Batista WL, Masutani H, Yodoi J. Debbas V, Augusto O, Stern A, Monteiro HP.
- Journal Title
  
  Toxicology and Applied Pharmacology 233
  
  Pages: 227-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013019
[Journal Article] Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses2008
- Author(s)
  Son A, Nakamura H, Okuyama-H, Oka S, Yoshihara E, Liu W, Matsuo Y,Koads N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1358-1367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013019
[Journal Article] Involvement of thioredoxin-binding protein 2 in the antitumor activity of CD4372008
- Author(s)
  Matsuoka S, Tsuchiya H, Sakabe T, Watanabe Y, Hoshikawa Y, Kurimasa A, Itamochi H, Harada T, Terakawa N, Masutani H, Yodoi J. Shiota G
- Journal Title
  
  Cancer Sci 99
  
  Pages: 2485-2490
- NAID
  10024014472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013019
[Journal Article] チオレドキシンによるレドックスとストレスシグナル制御2006
- Author(s)
  増谷弘
- Journal Title
  
  特集活性酸素・フリーラジカル機能と病態解明への新たな展開 : バイオスピンとシグナル伝達細胞工学 25
  
  Pages: 143-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590247
[Journal Article] チオレドキシンによるレドックスとストレスシグナル制御2006
- Author(s)
  増谷弘, 淀井淳司
- Journal Title
  
  特集活性酸素・フリーラジカル機能と病態解明への新たな展開 : バイオスピンとシグナル伝達細胞工学 25
  
  Pages: 143-148
- Data Source
  KAKENHI-PROJECT-17590247
[Journal Article] Redox regulation of human thioredoxin netwaork.2006
- Author(s)
  Kondo N, Nakamura H, Masutani H, Yodoi J
- Journal Title
  
  Antioxid Redox Signal 8
  
  Pages: 1881-1890
- Data Source
  KAKENHI-PROJECT-17590247
[Journal Article] The thioredoxin system in retroviral infection and apoptosis2005
- Author(s)
  Masutani H et al.
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 991-998
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590311
[Journal Article] The thioredoxin system in retroviral infection and apoptosis2005
- Author(s)
  Masutani H 他
- Journal Title
  
  Cell Death Differ. 12
  
  Pages: 991-998
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590311
[Journal Article] The thioredoxin system in retroviral infection and apoptosis2005
- Author(s)
  Masutani H 他
- Journal Title
  
  Cell Death Differ. (印刷中)
- Data Source
  KAKENHI-PROJECT-16590311
[Journal Article] Cytoprotective effects of geranylgeranylacetone against retinal photooxidative damage.2005
- Author(s)
  Tanito M, Kwon YW, Kondo N, Bai J, Masutani H, Nakamura H, Fujii J, Ohira A, Yodoi J.
- Journal Title
  
  Journal of Neuroscience 25(9)
  
  Pages: 2398-2404
- Data Source
  KAKENHI-PROJECT-17590247
[Presentation] レドックスラベルによる赤血球酸化ストレスモニター法の検討2020
- Author(s)
  曽山奉教, 平田クリスチアネ, 増谷弘
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07347
[Presentation] P-10喫煙における生物学的ストレス反応の新規高感度マーカーとしてのチオレドキシン2020
- Author(s)
  曽山奉教、増谷弘、平田クリスチアネ、金井恵理、稲本俊
- Organizer
  第73回　日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-20K07347
[Presentation] Thioredoxin interacting protein (Txnip) high molecular complexes contains differentially expressed mRNAs and IncRNAs.2020
- Author(s)
  Hirata Lumi Cristiane, Hiroshi Masutani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07347
[Presentation] アルファアレスチンによる白血病予後・代謝・細胞外小胞制御2018
- Author(s)
  増谷　弘
- Organizer
  第110回近畿血液学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08658
[Presentation] Thioredoxin interacting protein (Txnip)を応用した糖尿病・認知症治療薬の開発2018
- Author(s)
  増谷　弘, クリスチアネ　ルミ　ヒラタ, 大石真也, 藤井信孝
- Organizer
  第71回日本酸化ストレス学術集会
- Data Source
  KAKENHI-PROJECT-17K08658
[Presentation] レドックスシグナル研究からアルファアレスチンを応用した癌・糖尿病・認知症研究へ2018
- Author(s)
  増谷　弘
- Organizer
  Kyoto 60 Medical meeting
- Invited
- Data Source
  KAKENHI-PROJECT-17K08658
[Presentation] Thioredoxin interacting protein (Txnip) High order complex formation in cancer cells2018
- Author(s)
  Cristiane Lumi Hirata, Kanari Nishioka, Sae Ashida, Yoichi Mizutani, Shinji Ito, Iwai-Kanai Eri, Takashi Inamoto, Hiroshi Masutani
- Organizer
  第27回日本Cell Death 学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08658
[Presentation] Thioredoxin interacting protein (Txnip) High order complex formation in cancer cells2017
- Author(s)
  Cristiane Lumi Hirata, Kanari Nishioka, Sae Ashida, Yoichi Mizutani, Shinji Ito,　Hiroshi Masutani
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08658
[Presentation] thioredoxin interacting proteinによる癌抑制・糖代謝制御とケミカルバイロジー2016
- Author(s)
  増谷　弘
- Organizer
  第11回レドックス・ライフイノベーションシンポジウム
- Place of Presentation
  東京
- Year and Date
  2016-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-25460386
[Presentation] Regulation of glucose metabolism and protein degradation by Txnip in cancer suppression.2015
- Author(s)
  Hirata, C.L., Tateiri, K., Mizutani, Y., Ito, S., Masutani, H.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460386
[Presentation] アルファアレスチン分子TBP-2/Txnipによるエネルギー代謝制御と脂肪蓄積制御2012
- Author(s)
  増谷弘
- Organizer
  第33回日本肥満学会
- Place of Presentation
  京都
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] Deficiency of Thioredoxin binding protein-2 enhances TGF-beta signaling.2012
- Author(s)
  増谷弘
- Organizer
  第65回日本酸化ストレス学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] Thioredoxin binding protein-2 (TBP-2)/ Txnip/ VDUP1 with multifunctional biostress signal regulatory activities.2012
- Author(s)
  Masutani H
- Organizer
  Society for Free Radical Research International, 16th Biennial Meeting
- Place of Presentation
  ロンドン、イギリス
- Year and Date
  2012-09-06
- Invited
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] Deficiency of Thioredoxin binding protein-2 enhances TGF-beta signaling.2012
- Author(s)
  増谷弘
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] アルファアレスチン分子TBP-2/Txnipによる絶食応答・脂肪蓄積制御2011
- Author(s)
  増谷弘
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] Deficiency of Thioredoxin binding protein-2 (TBP-2) enhances TGF-beta signaling and contributes to TGF-beta-induced epithelial to mesenchymal transition2011
- Author(s)
  正木聡、淀井淳司、増谷弘
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] アルファアレスチン分子Thioredoxin binding protein-2 (TBP-2)/Txnipとメタボリック/酸化ストレス2011
- Author(s)
  増谷弘
- Organizer
  第22回日本眼科酸化ストレス研究会
- Place of Presentation
  大阪
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] 2型糖尿病モデルにおけるThioredoxin binding protein-2の役割2011
- Author(s)
  吉原栄治、藤本新平、稲垣暢也、大川克也、正木聡、淀井淳司、増谷弘
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PUBLICLY-23126512
[Presentation] Thioredoxin Binding Protein-2 is a key regulator of mitochondrial energy production and membrane potential2009
- Author(s)
  Yoshihara E, Fujimoto. S, Inagaki N, Yodoi J, and Masutani H
- Organizer
  Keystone symposium, Cell Death Pathways
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-20013019
[Presentation] Thioredoxin and thioredoxin binding protein-2 (TBP-2) Txnip in oncology and metabolism.2009
- Author(s)
  増谷弘
- Organizer
  SFRR international Free Radical School in Japan
- Place of Presentation
  Joetsu, Niigata
- Data Source
  KAKENHI-PROJECT-20013019
[Presentation] Thioredoxin regulates cell cycle via the ERK1/2-Cyclin D1 pathway.2009
- Author(s)
  増谷弘
- Organizer
  5^<th> Joint meeting of the societies for free radical research Australasia and Japan
- Place of Presentation
  Sydney Australia
- Data Source
  KAKENHI-PROJECT-20013019
[Presentation] Transmembrane thioredoxin-related protein in the endoplasmic reticulum : substrate recognition by TMX and its role in the inflammatory response2008
- Author(s)
  Yoshiyuki Matsuo, Kana Suzuki, Aoi Son, Hiroaki Okayama, Hajime Nakamura, Hiroshi Masutani, Junji Yodoi
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸(神戸国際会議場)
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20013019
[Presentation] TBP-2欠損の肥満・糖尿病モデルマウスは肥満になるが、高血糖にはならない2008
- Author(s)
  吉原栄治、藤本新平、稲垣暢也、淀井淳司、増谷弘
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸(神戸国際会議場)
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20013019
[Presentation] Thioredoxin binding protein-2 (TBP-2) is a multifunctional biostress signal regulator
- Author(s)
  Cristiane Lumi Hirata and Hiroshi MASUTANI
- Organizer
  Society for Free Radical Research International
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460386
[Presentation] Thioredoxin binding protein-2 (TBP-2)/Txnip is a critical regulator of energy balance
- Author(s)
  Hiroshi MASUTANI
- Organizer
  Society for Free Radical Research International, satellite meeting
- Place of Presentation
  Kyoto
- Invited
- Data Source
  KAKENHI-PROJECT-25460386
[Presentation] Development of redox modulating approaches against cancer and diabetes by Thioredoxin binding protein-2 (TBP-2) /Txnip
- Author(s)
  Hiroshi MASUTANI and Cristiane Lumi Hirata
- Organizer
  Society for Free Radical Research International
- Place of Presentation
  Kyoto
- Invited
- Data Source
  KAKENHI-PROJECT-25460386

1. YODOI Junji (80108993)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. NAKAMURA Hajime (70303914)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. GOTO Masafumi (50400453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OKADA Hidechika (30160683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUJII Nobutaka (60109014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OISHI Sinya (80381739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITOH Shinji (50362512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TAKABAYASHI Arimichi (00226911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IWATA Shogo (80291904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NABESHIMA Yo-ichi (60108024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UEDA Shugo (80372580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 薄井裕治 (70260164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 広田喜一 (00283606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 近藤則彦 (50378949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松尾禎之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 安永純一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中尾篤人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masutani Hiroshi 増谷 弘

Masutani HIroshi 増谷 弘

MASUTANI Hiroshi 増谷 弘

増谷 弘 マスタニ ヒロシ

Research Projects

Research Products

Co-Researchers

Development of stratified diagnostic method of breast cancer and elucidation of the regulatory mechanism of RNA based on Txnip researchPrincipal Investigator

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Metabolic regulation and cancer suppression by Thioredoxin interacting protein (Txnip) ribonucleoprotein complexPrincipal Investigator

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Elucidation of the molecular mechanism of insulin resistance by investigating TBP-2/Txnip and chemical biologyPrincipal Investigator

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アルファアレスチンによる絶食応答・脂肪蓄積制御Principal Investigator

Principal Investigator

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Establishment of a next generation cell therapy for diabetes based on Thioredoxin and C5a inhibitory peptide

Principal Investigator

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レドックス制御分子による癌細胞の増殖・死の調節機構の研究Principal Investigator

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Analysis of the mechanism and biological function of the internalization of thioredoxin into cells via lipid raft.

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Effect of oxidative stress and redox-regulating proteins on tumor growth and chemosensitivity

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The study on the regulation of cellular growth and aging process by thioredoxin binding protein

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チオレドキシンシステムのプロテオーム解析による感染宿主応答分子機構の研究

Principal Investigator

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Investigation of biological function of thioredoxin by construction of thioredoxin knock down micePrincipal Investigator

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ANALYSIS OF OXIDATIVE STRESS INDUCED APOPTOSIS MECHANISM AND THE BINDING PROTEINS TO THE OXIDATIVE RESPONSIVE ELEMENTPrincipal Investigator

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ANALYSIS AND ITS CLINICAL APPLICATION OF REDOX REGULATION MECHANISM FOR SURGICAL STRESS

Masutani Hiroshi 増谷弘

Masutani HIroshi 増谷弘

MASUTANI Hiroshi 増谷弘

増谷弘マスタニヒロシ