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KUGE Sayuri  久下 小百合

ORCIDConnect your ORCID iD *help
Researcher Number 50260104
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 九州大学, 理学研究院, 学術研究員
2014 – 2015: 九州大学, 理学(系)研究科(研究院), 学術研究員
2014: 九州大学, 大学院理学研究院, 学術研究員
2000: SASAKI INSTITUTE, Dept.of Biochemistry, Researcher, 生化学部, 研究員
1999: 財団法人 佐々木研究所, 生化学部, 研究員 … More
1999: SASAKI INSTITUTE, Dept. of Biochemistry, Researcher, 生化学部, 研究員
1998: 佐々木研究所, 生化学部, 研究員
1994 – 1996: (財)佐々木研究所, 生化学部, 研究員
1995: (財)佐々木研究所, 生化学的, 研究員 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Basic / Social brain science
Except Principal Investigator
Structural biochemistry / Biological Sciences / Neuroscience in general
Keywords
Principal Investigator
VIP36 / intracellular transport / high-mannose type sugar chain / lectin / MDCK cell / 細胞内輸送 / 高マンノース型糖鎖 / レクチン / MDCK細胞 / epsilon-COP … More / Coatomer / Vesicle Transport / ζ-COP / _ε-COP / coatmer / ε-COP / coatomer / 小胞輸送 / インバース / 線虫 / 神経活動 / カルシウムプローブ … More
Except Principal Investigator
lectin / MDCK cell / VIP36 / MDCK細胞 / 線虫 / イメージング / 神経科学 / レクチン様活性 / 学習 / 嗅覚 / 行動 / 行動遺伝学 / カルシウムイメージング / 忘却 / 記憶 / photoaffinity labeling / secretion / N-acetylalactosamine / N-linked sugar chain / 細胞内輸送 / フォトアフィニティーラベル / 分泌 / N-アセチルガラクトサミン / レクチン / N-結合型糖鎖 / VIP 36 / N-linked oligosaccharide / sorting / polariry / ソーティング / GPI-アンカー / Vip36 / N-結合糖鎖 / 選別 / 極性 / 情報処理 / アルカリ性ホスファターゼ / マンノース-6ーリン酸 / インターロイキン-1β / GPIアンカー / type2鎖 / 硫酸化糖鎖 / アスパラギン-N-結合型糖鎖 / 組織染色 / キカラスウリレクチン-I / 癌胎児性抗原 / 大腸癌 / 腫瘍マーカー Less
  • Research Projects

    (9 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (13 People)
  •  Development of new inverse-type calcium probe for analysis of inhibitory neuronal activitiesPrincipal Investigator

    • Principal Investigator
      Kuge Sayuri
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Basic / Social brain science
    • Research Institution
      Kyushu University
  •  Memory dynamism elucidated by studying on the mechanisms of forgetting in C. elegans

    • Principal Investigator
      Ishihara Takeshi
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Establishing a new method to analyze neuronal activities of all individual neurons of C. elegans CNS.

    • Principal Investigator
      ISHIHARA Takeshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neuroscience in general
    • Research Institution
      Kyushu University
  •  Synthesis of photo-affinity oligosaccharide probe and LacdiNAc sequence specific for secretory glycoproteins in MDCK cells

    • Principal Investigator
      OHKURA Takashi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      SASAKI INSTITUTE
  •  Function analysis of VIP36 related to protein sorting in intracellular transportPrincipal Investigator

    • Principal Investigator
      KUGE Sayuri
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      SASAKI INSTITUTE
  •  種々のサイトカインのレクチン様活性とその生理的意義に関する研究

    • Principal Investigator
      山下 克子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sasaki Institute
  •  A FUNCTIONAL ROLE OF N-GLYCANS AS SORTING SIGNALS FOR GLYCOPROTEINS IN EPITHELIAL CELLS

    • Principal Investigator
      OAMURA Takashi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      SASAKI INSTITUTE
  •  糖蛋白質糖鎖の変化を応用したがん個性の質的診断法に関する基礎研究

    • Principal Investigator
      山下 克子
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sasaki Institute
  •  FUNCTION ANALYSIS OF COATOMER IN VESICLE TRANSPORTPrincipal Investigator

    • Principal Investigator
      KUGE Sayuri
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      SASAKI INSTITUTE

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] An improved inverse-type Ca2+ indicator can detect putative neuronal inhibition in Caenorhabditis elegans by increasing signal intensity upon Ca2+ decrease2018

    • Author(s)
      Hara-Kuge S, Nishihara T, Matsuda T, Kitazono T, Teramoto T, Nagai T and Ishihara T
    • Journal Title

      PLOS ONE

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25115009
  • [Journal Article] Multiple Signaling Pathways Coordinately Regulate Forgetting of Olfactory Adaptation through Control of Sensory Responses in Caenorhabditis elegans2017

    • Author(s)
      Kitazono T, Hara-Kuge S, Matsuda O, Inoue A, Fujiwara M, Ishihara T
    • Journal Title

      J Neurosci

      Volume: 37(42) Issue: 42 Pages: 10240-10251

    • DOI

      10.1523/jneurosci.0031-17.2017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07503, KAKENHI-PLANNED-25115009, KAKENHI-PROJECT-16K19219, KAKENHI-PROJECT-17H06113
  • [Journal Article] Accurate Automatic Detection of Densely Distributed Cell Nuclei in 3D Space.2016

    • Author(s)
      Toyoshima Y, Tokunaga T, Hirose O, Kanamori M, Teramoto T, Jang MS, Kuge S, Ishihara T, Yoshida R, Iino Y.
    • Journal Title

      PLoS Comput Biol.

      Volume: 12 Issue: 6 Pages: 1-20

    • DOI

      10.1371/journal.pcbi.1004970

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25115009, KAKENHI-PLANNED-25115010, KAKENHI-PROJECT-26291069, KAKENHI-PROJECT-15K16021, KAKENHI-PROJECT-26830006, KAKENHI-PUBLICLY-16H01418
  • [Journal Article] The peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II2015

    • Author(s)
      Jiang, L., Hara-Kuge, S., Yamashita, S., and *Fujiki, Y.
    • Journal Title

      Genes to Cells

      Volume: 20 Issue: 1 Pages: 36-49

    • DOI

      10.1111/gtc.12198

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24247038, KAKENHI-PUBLICLY-25112518, KAKENHI-PUBLICLY-25116717, KAKENHI-PLANNED-26116007, KAKENHI-PROJECT-15K14511, KAKENHI-PROJECT-26560461
  • [Journal Article] Automated detection and tracking of many cells by using 4D live-cell imaging data2014

    • Author(s)
      Terumasa Tokunaga, Osamu Hirose, Shotaro Kawaguchi, Yu Toyoshima, Takayuki Teramoto, Hisaki Ikebata, Sayuri Kuge, Takeshi Ishihara, Yuichi Iino, Ryo Yoshida
    • Journal Title

      Bioinformatics

      Volume: 5;30(12) Issue: 12 Pages: 43-51

    • DOI

      10.1093/bioinformatics/btu271

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24570009, KAKENHI-PROJECT-24650167, KAKENHI-PLANNED-25115009
  • [Presentation] 抑制性神経活動を検出する消光型蛍光カルシウムプローブタンパク質2017

    • Author(s)
      久下 小百合、西原 知伸、松田 知己、寺本 孝行、永井 健治、石原 健
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PLANNED-25115009
  • [Presentation] An inverse-type of fluorescent Ca2+ indicator for detecting neuronal inhibition2017

    • Author(s)
      Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Takayuki Teramoto, Takeharu Nagai and Takeshi Ishihara
    • Organizer
      21st International C.elegans Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25115009
  • [Presentation] 線虫C. elegansにおいて、嗅覚順応の忘却は複数のシグナル伝達経路による感覚応答の調節により、協調的・時間的に制御される2017

    • Author(s)
      北園 智弘、久下 小百合、井上 明俊、藤原 学、石原 健
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PLANNED-25115009
  • [Presentation] 線虫C. elegansにおいて、記憶の忘却は、感覚応答をコントロールを介して、複数のシグナル伝達経路により、協調的・時期特異的に行われる2017

    • Author(s)
      北園 智弘、久下 小百合、井上 明俊、藤原 学、石原 健
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-25115009
  • [Presentation] 抑制性神経活動を検出する消光型蛍光カルシウムプローブタンパク質2015

    • Author(s)
      久下小百合、西原知伸、松田知己、古家博信、寺本孝行、永井健治、石原健
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] 線虫C.elegansの頭部神経系全体のGCaMP6fを用いた活動解析2015

    • Author(s)
      大江紗、寺本孝行、徳永旭将、広瀬修、豊島有、久下小百合、飯野雄一、吉田亮、石原健
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] Quenching-type of fluorescent Ca2+ indicator for detecting neuronal inhibition2015

    • Author(s)
      Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Hironobu Furuie, Takayuki Teramoto, Takeharu Nagai, Takeshi Ishihara
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] Ca2+ dependent negative feedback loop in AWC olfactory neurons2015

    • Author(s)
      Mamoru Usuyama, Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara, YUishi Iwasaki
    • Organizer
      C.elegans 2015 20th International Meeting
    • Place of Presentation
      University of California
    • Year and Date
      2015-06-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] A quenching-type of fluorescent Ca2+ indicator for detecting neuronal inhibition2015

    • Author(s)
      Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Hironobu Furuie, Takayuki Teramoto, Takeharu Nagai, Takeshi Ishihara
    • Organizer
      C.elegans 2015 20th International Meeting
    • Place of Presentation
      University of California
    • Year and Date
      2015-06-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] 線虫、C. elegansの単一神経細胞におけるカルシウムダイナミクス

    • Author(s)
      久下(原) 小百合、寺本 孝行、 石原 健
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650167
  • [Presentation] Tracking of Ca2+ dynamics in a whole single neuron

    • Author(s)
      Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara
    • Organizer
      Neuronal Development, Synaptic Function and Behavior
    • Place of Presentation
      University of Wisconsin-Madison
    • Year and Date
      2014-07-07 – 2014-07-10
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] 単一ニューロンにおけるCa2+ダイナミクス

    • Author(s)
      久下 小百合、 寺本 孝行、 石原 健
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-03 – 2013-12-06
    • Data Source
      KAKENHI-PLANNED-25115009
  • [Presentation] Tracking of Ca2+ dynamics in a whole single neuron

    • Author(s)
      Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara
    • Organizer
      2014 C. elegans topic meeting: Neuronal Development, Synaptic Function and behavior
    • Place of Presentation
      米国 マディソン
    • Year and Date
      2014-07-07 – 2014-07-09
    • Data Source
      KAKENHI-PROJECT-24650167
  • [Presentation] 線虫、C.elegansの単一神経細胞におけるカルシウムダイナミクス

    • Author(s)
      久下小百合、寺本孝行、石原健
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] Electrodifusion model for Ca2+ dynamics in a whole single neuron

    • Author(s)
      Yuishi Iwasaki, Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara
    • Organizer
      Neuronal Development, Synaptic Function and Behavior
    • Place of Presentation
      University of Wisconsin-Madison
    • Year and Date
      2014-07-07 – 2014-07-10
    • Data Source
      KAKENHI-PROJECT-26560461
  • [Presentation] 線虫、C.elegansの単一神経細胞におけるカルシウムダイナミクス

    • Author(s)
      久下 小百合、 寺本 孝行、 石原 健
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PLANNED-25115009
  • 1.  OAMURA Takashi (50183223)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  ISHIHARA Takeshi (10249948)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 3.  TERAMOTO Takayuki (90571836)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 4.  山下 克子 (70030905)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  福島 慶子 (10250010)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAGAI Takeharu (20311350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  MATSUDA Tomoki (50419206)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  FUJIWARA Manabi (70359933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  SAWATARI Etsuko (60456605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ARAI Miari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KITAZONO Tomohiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  山下 俊英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  藤木 幸夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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