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UCHIDA Shinichi  内田 信一

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Researcher Number 50262184
Other IDs
Affiliation (Current) 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 教授
2016: 東京医科歯科大学, 医歯学総合研究科, 教授
2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授
2011 – 2013: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授
2007 – 2012: Tokyo Medical and Dental University, Deptt of Nephrology, Associate Professor … More
2009 – 2010: Tokyo Medical and Dental University, 医歯学総合研究科, 准教授
2007: 東京医科歯科大学, 医歯学総合研究科, 准教授
2006: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授
2005 – 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助教授
2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授
2004 – 2005: Tokyo Medical and Dental University, Department of Nephrology, Associate professor, 医歯学総合大学院, 助教授
2003 – 2004: 東京医科歯科大学, 大学院・医学研究科, 講師
2001 – 2004: 東京医科歯科大学, 医学部附属病院, 講師
2000 – 2001: 東京医科歯科大学, 医学部・附属病院, 講師
1995 – 1998: Tokyo Medical and Dental University, School of Medicine, Instructor, 医学部, 助手
1994: 東京医科歯科大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Kidney internal medicine / Biological Sciences / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53040:Nephrology-related
Except Principal Investigator
Kidney internal medicine / Kidney internal medicine / Pediatrics / Embryonic/Neonatal medicine
Keywords
Principal Investigator
クロライドチャネル / 高血圧 / WNKキナーゼ / 腎臓 / ノックアウトマウス / 水チャネル / キナーゼ / CLCクロライドチャネル / 塩分感受性高血圧 / 尿崩症 … More / 膜輸送体 / ノックインマウス / リン酸化酵素 / ケミカルライブラリー / 創薬 / ソーティング / トランスジェニックマウス / MDCK細胞 / CLC chloride channel / in situ hybridization / AQP水チャネル / アルドステロン / 遺伝子改変マウス / AKAP / 遺伝子組み換えマウス / 偽性低アルドステロン症II型 / claudin / Na-Cl共輸送体 / 蛋白複合体 / 細胞内局在 / 尿濃縮 / 上皮輸送 / 免疫沈降 / AQP water channel / sorting / transgenic mice / trans-epithelial transport / バーター症候群 / Bartter syndrome / AKAPs / 先天性腎性尿崩症 / 肥満症 / ORCC / CFTR / CIC-3 / cAMP / CIC-5 / patch-clamp / Antisense / KLF / ジーンターデティング / マウス / 転写因子 / RT-PCR / 酵母two-hybrid法 / 水・電解質代謝学 / リン酸化 / 輸送体 / 遺伝子改変動物 / WNK4ノックアウトマウス / SGKノックアウトマウス / 細胞容積調節 / 水 / 電解質代謝学 / メタボリックシンドローム / 塩分ストレス / 次世代シークエンサー / 脂肪分化 / ストレス / 内科 / E3ユビキチンリガーゼ / シグナル伝達 / WNK キナーゼ / キナーゼ阻害薬 / 免疫組織化学 / 遺伝子 / FISH法 / イオントランスポート / chloride channel / immunohistochemistry / human gene / FISH method / アクアポリン / 酵母 / 集合管 / 膜輸送 / タンパク構造 / AQP2 / バゾプレシン / 利尿剤 / 尿濃縮機構 / 集合尿細管 / Aquaporin / Water transport / Yeast / Kidney / Collecting duct / Membrane transport / Protein Structure / CLCファミリー / ジーンターゲッティング / In situ hybridization / 特発性尿細管性たんぱく尿症 / Choride channel / CLC family / gene targeting / in citu hybridization / diabetes insidipus / MPCK細胞 / 細胞内膜系 / クロライドチャンネル / 対向流系 / chloride Channel / counter current system / knockout mice / ゴルジ体 / エンドソーム / ライソゾーム / neuronal ceroid lipofuscinosis / F1F0-ATPase / Iysosomal storage disease / intracellular sorting / Golgi / MDCK cells / immunoprecipitation / バーチン / Xenous oocyte / barttin / phosphorylation / hypertension / pseudohypoaldosteronism / knockin mouse / thiazide / 水・電荷室 / E3リガーゼ / ユビキチンE3リガーゼ / Kelch-like protein / WNK kinase / WNKシグナル / 生活習慣病 / メタボリック症候群 / 炎症性サイトカイン / TNFα / WNK4 / 3T3-L1 / CRISPR/Cas9 / 質量分析 / protein kinase A / AKAPs-PKA結合阻害 / PKA / 腎性尿崩症 / Protein Kinase A / 腎性尿放送 / AQP2 water channel / 結合阻害薬 / 褐色脂肪細胞 / Protein kinase A … More
Except Principal Investigator
腎臓 / クロライドチャネル / アクチン / パッチクランプ / 水チャネル / アクアポリン / 嚢胞腎 / チャネル / ADH / 輸送体 / クローニング / Dent's病 / AQP-2 / AQP-3 / CLC-K1 / CLC-K2 / CRE / GATA / 尿濃縮機構 / urine concentrating mechanism / カリウムチャネル / 細胞骨格 / 蛋白-蛋白相互作用 / 酵母2ハイブリッド / 水輸送 / 尿崩症 / 膵炎 / リン脂質結合蛋白 / トロポミオシン / 蛍光相関分光 / 遺伝子改変マウス / リト脂質結合蛋 / AKAP / 酵母two-hybrid法 / 細胞内輸送 / プロテオミクス / グリセロール / 膜蛋白質 / 微小単離尿細管灌流法 / 経上皮電位 / アポトーシス / 中心繊毛 / 管腔内圧 / ヘンレの太い上行脚 / 皮質部集合管 / ARPKD / PCKラット / 徴小単離尿細管灌流 / 抗利尿ホルモン / ヘンレループ / 慢性腎不全 / 腎尿細管 / 移植・再生医療 / 医療・福祉 / 解剖学 / 細胞・組織 / 病理学 / 腎嚢胞 / イオン輸送 / イオンチャンネル / 絨毛 / 小児末期腎不全 / 利尿薬 / 多嚢胞腎 / 集合管 / 細いヘンレの上行脚 / 細胞間隙 / ナトリウムイオン輸送 / ナトリウム輸送 / ATL / インスリン / 尿細管 / クローディン4 / アルドステロン / 拡散電位 / 国際情報交流 / 尿濃縮 / 膜タンパク / 腎輸送体 / Water channel / Aquaporin / Chloride channel / Kidney / クロライド / PCR / CIC-5 / マイクロインジェクション / chloride / channel / cloning / patch-clamp / kidney / molecular biology / プロモーター / Gリッチエレメント / 転写調節 / 核内タンパク / 遺伝子制御 / Promoter / purine-rich sequence / CIC-5クロライドチャネル / 細胞内小胞 / エンドサイトーシス / H^+-ポンプ / 低分子タンパク尿 / モノクロナール抗体 / ClC-5 / CLCN5 / ゲノムDNA / Dent病 / CIC-5 chloride channel / cytoplasmic vesicle / endocytosis / H^+-ATPase / low molecular V proteinuria weight / monoclonal antibody / Dent's disease / 希釈セグメント / 系統発生 / 個体発生 / 新生児 / 質的転換 / NaCl輸送体 / 出生 / 腎機能 / 成熟過程 / 腎髄質部 / 尿素 / 在胎日数 / ヘンレの細い上行脚 / 形質転換 / diluting segments / phylogeny / ontogeny / neonatology / transformation / NaCl tranporters / birth / イオン輸送体 / カルシウム代謝 / 尿細管機能異常症 / 微笑灌流法 / 顕微蛍光測光法 / 微小灌流法 / ion transporters / calcium metabolism / renal tubular dysfunction / microperfusion / microfluorometry / ストレス / 脳発達 / WNK / KCC2 / GABA / コルチコステロン / GAD / 低栄養 / 塩分負荷 / CRH Less
  • Research Projects

    (31 results)
  • Research Products

    (369 results)
  • Co-Researchers

    (71 People)
  •  病態に直結するPKAシグナル伝達機構の解明と治療法開発Principal Investigator

    • Principal Investigator
      内田 信一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Application of AKAPs-PKA disruptors in the treatment of PKA-related diseasesPrincipal Investigator

    • Principal Investigator
      Uchida Shinichi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of novel preventive drugs for lifestyle disease by inhibiting WNK4 signalingPrincipal Investigator

    • Principal Investigator
      Shinichi Uchida
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  KLHL2/3 as molecular targets to modulate WNK kinasesPrincipal Investigator

    • Principal Investigator
      UCHIDA SHINICIH
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Models for developmental disorder induced by interaction of maternal stress and fetal factors

    • Principal Investigator
      Fukuda Atsuo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Hamamatsu University School of Medicine
  •  Salt stress-induced responses in health and disease: the role of WNK kinases and new therapeutic strategiesPrincipal Investigator

    • Principal Investigator
      UCIDA Shinichi
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  WNKキナーゼの制御機構とその破綻病態の解明Principal Investigator

    • Principal Investigator
      内田 信一
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of SPAK kinase inhibitorsPrincipal Investigator

    • Principal Investigator
      UCHIDA SHINICHI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of paracellular sodium ion transport in the thin ascending limb of Henle's loop

    • Principal Investigator
      MORIMOTO TETSUJI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Nihon University
  •  Efficient chemical library screening for WNK signaling inhibitors byinhibiting WNK-SPAK interactionPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  A novel WNK signal cascade regulating renal transportersPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi (UCHIDA Sinichi)
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular physiological analyses of renal failure in pediatric cystic renal diseases

    • Principal Investigator
      KONDO Yoshiaki
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Nihon University
      Tohoku University
  •  Analysis of abnormal chloride transport in the pathogenesis of renal electrolyte disordersPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification of renal transportsomes by analyzing disease-causing mutants of transporters and their regulators.Principal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Function and regulatory system of water transporting aquaporin channels

    • Principal Investigator
      SASAKI Sei
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Tokyo Medical and Dental University
  •  Regulation of CLC chloride channels by their beta-subunitsPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Developmental analyses of Ca transporters and Ca sensing receptors in the kidneys

    • Principal Investigator
      KONDO Yoshiaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tohoku University
  •  腎臓の発生分化におけるKruppel-like転写因子の役割の解明Principal Investigator

    • Principal Investigator
      内田 信一
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies on the physiological roles of intracellular OLO chloride channelsPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Ontogenetic and Phylogenelic anaylses of factors affecting the developmental process in crine concentrating mechanism

    • Principal Investigator
      KONDO Yoshiaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tohoku University
  •  Intracellular trafficking mechanisms of renal C1C and AQP channelsPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of urine concentrating mechanisms using the CLC-K1 null mice.Principal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      TOKYO MEDEICAL AND DENTAL UNIVERSITY
  •  アクチン細胞骨格を介するABCトランスポーターとイオンチャネルの機能共役

    • Principal Investigator
      古川 哲史
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  Cellular and Subcellular Immunolocalization of CIC-5 Chloride Channel in the mouse Kidney : Colocalization with H^+-ATPase

    • Principal Investigator
      SAKAMOTO Hisato
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  CLC Chloride channels and diseasesPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      TOKYO MEDICAL AND DENTAL UNIVERSITY
  •  カルシウム感受性外向き整流性クロライドチャネルの構造・機能相関Principal Investigator

    • Principal Investigator
      内田 信一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  Transcriptional regulation of kidney-specific genes

    • Principal Investigator
      INASE Naohiko, 佐々木 成
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of membrane permeation inhibitors which are specific for kidney collecting duct, based on protein structure-function analysis.Principal Investigator

    • Principal Investigator
      UCHIDA Shinichi, 丸茂 文昭
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Roles of cloned chloride channels in kidney chloride transportPrincipal Investigator

    • Principal Investigator
      UCHIDA Shinichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular biological examination of Calcium-sensitive Chloride Channel expressed in the kidney

    • Principal Investigator
      SAKAMOTO Hisato
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Cloning of kidney membrane transport proteins and characterization of its function

    • Principal Investigator
      SASAKI Sei
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo Medical and Dental University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2001 2000 Other

All Journal Article Presentation Book Patent

  • [Book] 脱水腎と透析2012

    • Author(s)
      笠木祐里,内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 細胞工学2012

    • Author(s)
      内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 日本臨床別冊腎臓症候群(上)2012

    • Author(s)
      高橋大栄,内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 今日の治療指針2011 急性腎不全2011

    • Author(s)
      内田信
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] トランスポートソームの世界2011

    • Author(s)
      日比野浩,内田信一,野村尚弘
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 遺伝子医学MOOK19トランスポートソーム生体膜輸送機構の全体像に迫る2011

    • Author(s)
      須佐紘一郎,内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 医学のあゆみ2011

    • Author(s)
      三澤慕子,内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 内分泌・糖尿病・代謝内2011

    • Author(s)
      若林麻衣,内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 2-6非興奮性細胞(非興奮性組織)のイオンチャネル2-6-2上皮.トランスポートソームの世界.金井好克/竹島浩/森泰生/久保義弘編著2011

    • Author(s)
      日比野浩, 内田信一, 野村尚弘
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] 2-2膜電位とイオンチャネル2-2-4「膜電位とチャネル」クロライド.トランスポートソームの世界.金井好克/竹島浩/森泰生/久保義弘編著2011

    • Author(s)
      内田信一, 野村尚弘
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] 腎疾患・透析 最新の治療2011-2013(尿崩症)2011

    • Author(s)
      内田信
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] バソプレシンと病態形成の関わり2011

    • Author(s)
      野村尚弘,内田信一
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] トランスポートソームの世界. 金井好克/竹島浩/森泰生/久保義弘編著2011

    • Author(s)
      内田信一, 野村尚弘.
    • Total Pages
      471
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Book] 電解質輸送体の調節機構についての新たな進展Anuual Reciew 腎臓20102010

    • Author(s)
      太田哲人、内田信一
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] 医学スーパラーニングシリーズ 腎臓内科学 (内分泌機能、水電解質の代謝)2010

    • Author(s)
      内田信
    • Publisher
      シュプリンガー・ジャパン
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] Annual Review 腎臓2010(電解質輸送体の調節機構についての新たな進展)2010

    • Author(s)
      太田哲人、内田信
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] Neural roles of CLC chloride channels.(Handbook of Neurochemistry and Molecular Neurobiology.)(3rd Edition.)(Editor : Abel Lajha)2009

    • Author(s)
      Uchida S, Sasaki S.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Book] 今日の治療指針2007、輸液療法2007

    • Author(s)
      内田 信一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Book] 今日の治療指針2007、輸液療法2007

    • Author(s)
      内田 信一
    • Publisher
      医学書院
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Book] 今日の治療指針2007、輸液療法2007

    • Author(s)
      内田 信一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Book] 偽性低アルドステロン症II型

    • Author(s)
      森崇寧,内田信一
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Generation of NPHP1 knockout human pluripotent stem cells by a practical biallelic gene deletion strategy using CRISPR/Cas9 and ssODN2022

    • Author(s)
      Nakano Yuta、Susa Koichiro、Yanagi Tomoki、Hiraoka Yuichi、Suzuki Takefumi、Mori Takayasu、Ando Fumiaki、Mandai Shintaro、Fujiki Tamami、Rai Tatemitsu、Uchida Shinichi、Sohara Eisei
    • Journal Title

      In Vitro Cellular & Developmental Biology - Animal

      Volume: 58 Pages: 85-95

    • DOI

      10.1007/s11626-022-00655-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H01049, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-21K08223
  • [Journal Article] Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney2021

    • Author(s)
      Takahashi Naohiro、Kikuchi Hiroaki、Usui Ayaka、Furusho Taisuke、Fujimaru Takuya、Fujiki Tamami、Yanagi Tomoki、Matsuura Yoshiaki、Asano Kenichi、Yamamoto Kouhei、Ando Fumiaki、Susa Koichiro、Mandai Shintaro、Mori Takayasu、Rai Tatemitsu、Uchida Shinichi、Arita Makoto、Sohara Eisei
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 25 Pages: 445-455

    • DOI

      10.1007/s10157-021-02021-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03672, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-19H01049, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K16181, KAKENHI-PROJECT-21K20710
  • [Journal Article] Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A)2021

    • Author(s)
      Nanamatsu Azuma、Mori Takayasu、Ando Fumiaki、Furusho Taisuke、Mandai Shintaro、Susa Koichiro、Sohara Eisei、Rai Tatemitsu、Uchida Shinichi
    • Journal Title

      Hypertension

      Volume: In press Pages: 1953-1963

    • DOI

      10.1161/hypertensionaha.121.17127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03672, KAKENHI-PROJECT-19K17733, KAKENHI-PROJECT-19H01049, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-21H02933, KAKENHI-PROJECT-21K08249
  • [Journal Article] 【水電解質】先天性腎性尿崩症の治療薬開発の現状2020

    • Author(s)
      安藤 史顕, 内田 信一
    • Journal Title

      日本腎臓学会誌

      Volume: 62 Pages: 798-802

    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Journal Article] Renal TNFα activates the WNK phosphorylation cascade and contributes to salt-sensitive hypertension in chronic kidney disease2020

    • Author(s)
      Furusho T, Sohara E, Mandai S, Kikuchi H, Takahashi N, Fujimaru T, Hashimoto H, Arai Y, Ando F, Zeniya M, Mori T, Susa K, Isobe K, Nomura N, Yamamoto K, Okado T, Rai T, Uchida S
    • Journal Title

      Kidney International

      Volume: 97 Pages: 713-727

    • DOI

      10.1016/j.kint.2019.11.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15970, KAKENHI-PROJECT-18K15995, KAKENHI-PROJECT-19K21299, KAKENHI-PROJECT-20K17244, KAKENHI-PROJECT-20K17276, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-19H03672
  • [Journal Article] Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease.2019

    • Author(s)
      Kikuchi H, Sasaki E, Nomura N, Mori T, Minamishima YA, Yoshizaki Y, Takahashi N, Furusho T, Arai Y, Mandai S, Yamashita T, Ando F, Maejima Y, Isobe K, Okado T, Rai T, Uchida S, Sohara E
    • Journal Title

      Kidney International

      Volume: 95 Pages: 123-137

    • DOI

      10.1016/j.kint.2018.08.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15995, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-16K09642, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-18K15970, KAKENHI-PROJECT-16H04723
  • [Journal Article] Tacrolimus ameliorates the phenotypes of type 4 Bartter syndrome model mice through activation of sodium?potassium?2 chloride cotransporter and sodium?chloride cotransporter2019

    • Author(s)
      Matsuura Yoshiaki、Nomura Naohiro、Shoda Wakana、Mori Takayasu、Isobe Kiyoshi、Susa Koichiro、Ando Fumiaki、Sohara Eisei、Rai Tatemitsu、Uchida Shinichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 517 Pages: 364-368

    • DOI

      10.1016/j.bbrc.2019.07.086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-19H03672, KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15970, KAKENHI-PROJECT-18K15995
  • [Journal Article] Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation2019

    • Author(s)
      Fujiki Tamami、Ando Fumiaki、Murakami Kana、Isobe Kiyoshi、Mori Takayasu、Susa Koichiro、Nomura Naohiro、Sohara Eisei、Rai Tatemitsu、Uchida Shinichi
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 9245-9245

    • DOI

      10.1038/s41598-019-45539-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16501, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-19H03672, KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15970
  • [Journal Article] Clinical importance of potassium intake and molecular mechanism of potassium regulation.2019

    • Author(s)
      Nomura N, Shoda W, Uchida S
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 23 Pages: 1175-1180

    • DOI

      10.1007/s10157-019-01766-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15995
  • [Journal Article] Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.2018

    • Author(s)
      Yoshida S, Araki Y, Mori T, Sasaki E, Kasagi Y, Isobe K, Susa K, Inoue Y, Bomont P, Okado T, Rai T, Uchida S, Sohara E
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 22 Pages: 1251-1257

    • DOI

      10.1007/s10157-018-1593-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15970, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-16K09642
  • [Journal Article] Role of ClC-K and barttin in low potassium-induced sodium chloride cotransporter activation and hypertension in mouse kidney2018

    • Author(s)
      Nomura Naohiro、Shoda Wakana、Wang Yuanlong、Mandai Shintaro、Furusho Taisuke、Takahashi Daiei、Zeniya Moko、Sohara Eisei、Rai Tatemitsu、Uchida Shinichi
    • Journal Title

      Bioscience Reports

      Volume: 38 Pages: 20171243-1243

    • DOI

      10.1042/bsr20171243

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-16K19478, KAKENHI-PROJECT-18K15995, KAKENHI-PROJECT-17K16076, KAKENHI-PROJECT-17K16077
  • [Journal Article] Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter2018

    • Author(s)
      Hashimoto Hiroko、Nomura Naohiro、Shoda Wakana、Isobe Kiyoshi、Kikuchi Hiroaki、Yamamoto Kouhei、Fujimaru Takuya、Ando Fumiaki、Mori Takayasu、Okado Tomokazu、Rai Tatemitsu、Uchida Shinichi、Sohara Eisei
    • Journal Title

      Metabolism

      Volume: 85 Pages: 23-31

    • DOI

      10.1016/j.metabol.2018.02.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09642, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15970, KAKENHI-PROJECT-18K15995, KAKENHI-PROJECT-16H05314
  • [Journal Article] WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.2018

    • Author(s)
      Mandai S, Mori T, Nomura N, Furusho T, Arai Y, Kikuchi H, Sasaki E, Sohara E, Rai T, Uchida S
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 9101-9101

    • DOI

      10.1038/s41598-018-27414-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15995, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-19K21299, KAKENHI-PROJECT-16K09642
  • [Journal Article] AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrognic diabetes insipidus.2018

    • Author(s)
      Ando Fumiaki、Mori Shuichi、Yui Naofumi、Morimoto Tetsuji、Nomura Naohiro、Sohara Eisei、Rai Tatemitsu、Sasaki Sei、Kondo Yoshiaki、Kagechika Hiroyuki、Uchida Shinichi
    • Journal Title

      Nature communications

      Volume: 9 Pages: 1-11

    • DOI

      10.1038/s41467-018-03771-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-15K09286, KAKENHI-PROJECT-18K08233, KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-18K15995, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-17H06656, KAKENHI-PROJECT-15K09301, KAKENHI-PROJECT-16K09642
  • [Journal Article] Kidney enlargement and multiple liver cyst formation implicate mutations in PKD1/2 in adult sporadic polycystic kidney disease2018

    • Author(s)
      Fujimaru T.、Mori T.、Sekine A.、Mandai S.、Chiga M.、Kikuchi H.、Ando F.、Mori Y.、Nomura N.、Iimori S.、Naito S.、Okado T.、Rai T.、Hoshino J.、Ubara Y.、Uchida S.、Sohara E.
    • Journal Title

      CLINICAL GENETICS

      Volume: 印刷中 Pages: 125-131

    • DOI

      10.1111/cge.13249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-16H05314
  • [Journal Article] Na-Cl cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats2018

    • Author(s)
      Yamauchi Takahiro、Doi Shigehiro、Nakashima Ayumu、Doi Toshiki、Sohara Eisei、Uchida Shinichi、Masaki Takao
    • Journal Title

      American Journal of Physiology-Renal Physiology

      Volume: 印刷中

    • DOI

      10.1152/ajprenal.00504.2016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Journal Article] Activation of AQP2 water channels without vasopressin: therapeutic strategies for congenital nephrogenic diabetes insipidus2018

    • Author(s)
      Ando F, Uchida S
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 22 Pages: 501-507

    • DOI

      10.1007/s10157-018-1544-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19534, KAKENHI-PROJECT-17H06656
  • [Journal Article] WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL32017

    • Author(s)
      Susa Koichiro、Sohara Eisei、Takahashi Daiei、Okado Tomokazu、Rai Tatemitsu、Uchida Shinichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 491 Pages: 727-732

    • DOI

      10.1016/j.bbrc.2017.07.121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09642, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-16K15467
  • [Journal Article] Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to?high potassium intake2017

    • Author(s)
      Shoda W, Nomura N, Ando F, Mori Y, Mori T, Sohara E, Rai T, Uchida S.
    • Journal Title

      Kidney International

      Volume: 91 Pages: 402-411

    • DOI

      10.1016/j.kint.2016.09.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-16H06772, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-16K19478
  • [Journal Article] The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-β12017

    • Author(s)
      Zeniya Moko、Mori Takayasu、Yui Naofumi、Nomura Naohiro、Mandai Shintaro、Isobe Kiyoshi、Chiga Motoko、Sohara Eisei、Rai Tatemitsu、Uchida Shinichi
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 13086-13086

    • DOI

      10.1038/s41598-017-13486-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16076, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16K15467
  • [Journal Article] Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice2017

    • Author(s)
      Kasagi Y, Takahashi D, Aida T, Nishida H, Nomura N, Zeniya M, Mori T, Sasaki E, Ando F, Rai T, Uchida S, Sohara E.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 487 Pages: 368-374

    • DOI

      10.1016/j.bbrc.2017.04.068

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-15H06183, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-16K07085, KAKENHI-PROJECT-16K09642, KAKENHI-PROJECT-17K16076, KAKENHI-PROJECT-16K19478
  • [Journal Article] KLHL3 knockout mice reveal the physiological role of KLHL3 and the pathophysiology of PHAII caused by mutant KLHL3.2017

    • Author(s)
      Sasaki E, Susa K, Mori T, Isobe K, Araki Y, Inoue Y, Yoshizaki Y, Ando F, Mori Y, Mandai S, Zeniya M, Takahashi D, Nomura N, Rai T, Uchida S, Sohara E.
    • Journal Title

      Molecular and Cellular Biology

      Volume: 27 Pages: 1-13

    • DOI

      10.1128/mcb.00508-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-15H06183, KAKENHI-PROJECT-16H06772, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-16K09642, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-17K16076
  • [Journal Article] Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy2017

    • Author(s)
      Mandai S, Furukawa S, Kodaka M, Hata Y, Mori T, Nomura N, Ando F, Mori Y, Takahashi D, Yoshizaki Y, Kasagi Y, Arai Y, Sasaki E, Yoshida S, Furuichi Y, Fujii NL, Sohara E, Rai T, Uchida S.
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 46369-46369

    • DOI

      10.1038/srep46369

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K16489, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-16K09642
  • [Journal Article] Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy2017

    • Author(s)
      Yoshizaki Yuki、Mori Takayasu、Ishigami-Yuasa Mari、Kikuchi Eriko、Takahashi Daiei、Zeniya Moko、Nomura Naohiro、Mori Yutaro、Araki Yuya、Ando Fumiaki、Mandai Shintaro、Kasagi Yuri、Arai Yohei、Sasaki Emi、Yoshida Sayaka、Kagechika Hiroyuki、Rai Tatemitsu、Uchida Shinichi、Sohara Eisei
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 3945-3945

    • DOI

      10.1038/s41598-017-04233-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16076, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-16K15467
  • [Journal Article] Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells2017

    • Author(s)
      Arai Y, Takahashi D, Asano K, Tanaka M, Oda M, Ko SBH, Ko MSH, Mandai S, Nomura N, Rai T, Uchida S, Sohara E.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 46580-46580

    • DOI

      10.1038/srep46580

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-15K14431, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-16K09642, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-15H04812, KAKENHI-PROJECT-17H04068
  • [Journal Article] WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice2017

    • Author(s)
      Takahashi D, Mori T, Sohara E, Tanaka M, Chiga M, Inoue Y, Nomura N, Zeniya M, Ochi H, Takeda S, Suganami T, Rai T, Uchida S.
    • Journal Title

      EBioMedicine.

      Volume: 18 Pages: 118-127

    • DOI

      10.1016/j.ebiom.2017.03.011

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01633, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-15H06183, KAKENHI-PROJECT-15H06184, KAKENHI-PROJECT-26713048, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K15545, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-16K09642, KAKENHI-PROJECT-17K16076, KAKENHI-PROJECT-17K16077, KAKENHI-PUBLICLY-17H05500, KAKENHI-PROJECT-15K09423, KAKENHI-PROJECT-16K15234
  • [Journal Article] Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway2016

    • Author(s)
      Ando F, Sohara E, Morimoto T, Yui N, Nomura N, Kikuchi E, Takahashi D, Mori T, Vandewalle A, Rai T, Sasaki S, Kondo Y, Uchida S.
    • Journal Title

      Nat Commun

      Volume: 7 Pages: 1-12

    • DOI

      10.1038/ncomms13636

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K09286, KAKENHI-PROJECT-15K09301, KAKENHI-PROJECT-16K15467
  • [Journal Article] Involvement of selective autophagy mediated by p62/SQSTM1 in KLHL3-dependent WNK4 degradation.2015

    • Author(s)
      Mori Y, Mori T, Wakabayashi M, Yoshizaki Y, Zeniya M, Sohara E, Rai T, Uchida S.
    • Journal Title

      Biochemical J

      Volume: 472 Pages: 33-41

    • DOI

      10.1042/bj20150500

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-26860629
  • [Journal Article] Discovery of novel SPAK inhibitors that block WNK kinase signaling to cation chloride transporters.2015

    • Author(s)
      Kikuchi E, Mori T, Zeniya M, Isobe K, Ishigami-Yuasa M, Fujii S, Kagechika H, Ishihara T, Mizushima T, Sasaki S, Sohara E, Rai T, Uchida S
    • Journal Title

      J. Am. Soc. Nephrol.

      Volume: 26 Pages: 1525-1536

    • DOI

      10.1681/asn.2014060560

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-26670428
  • [Journal Article] Kelch-like protein 2 mediates angiotensin II-with no lysine 3 signaling in the regulation of vascular tonus2015

    • Author(s)
      Zeniya M, Morimoto N, Takahashi D, Mori Y, Mori T, Ando F, Araki Y, Yoshizaki Y, Inoue Y, Isobe K, Nomura N, Oi K, Nishida H, Sasaki S, Sohara E, Rai T, Uchida S
    • Journal Title

      J Am Soc Nephrol.

      Volume: 26 Pages: 2129-2138

    • DOI

      10.1681/asn.2014070639

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-26860628
  • [Journal Article] Generation and analysis of knock-in mice carrying pseudohypoaldosteronism type II-causing mutations in the cullin 3 gene2015

    • Author(s)
      Araki Y, Rai T, Sohara E, Mori T, Inoue Y, Isobe K, Kikuchi E, Ohta A, Sasaki S, Uchida S.
    • Journal Title

      Biol Open.

      Volume: 4 Pages: 1509-1517

    • DOI

      10.1242/bio.013276

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25461243, KAKENHI-PROJECT-26670428
  • [Journal Article] Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL32015

    • Author(s)
      Yoshizaki Y, Mori Y, Tsuzaki Y, Mori T, Nomura N, Wakabayashi M, Takahashi D, Zeniya M, Kikuchi E, Araki Y, Ando F, Isobe K, Nishida H, Ohta A, Susa K, Inoue Y, Chiga M, Rai T, Sasaki S, Uchida S, Sohara E.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 467 Pages: 229-234

    • DOI

      10.1016/j.bbrc.2015.09.184

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25461243, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-15K19445, KAKENHI-PROJECT-26860628, KAKENHI-PROJECT-26860629
  • [Journal Article] Generation of Hypertension-Associated STK39 Polymorphism Knockin Cell Lines With the Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 System.2015

    • Author(s)
      Mandai S, Mori T, Sohara E, Rai T, Uchida S.
    • Journal Title

      Hypertension.

      Volume: 66 Pages: 1199-1206

    • DOI

      10.1161/hypertensionaha.115.05872

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-26670428
  • [Journal Article] Genetic knockout and pharmacologic inhibition of NCX2 cause natriuresis and hyper-calciuria.2015

    • Author(s)
      Gotoh Y, Kita S, Fujii M, Tagashira H, Horie I, Arai Y, Uchida S, Iwamoto T
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 456 (2) Pages: 230-238

    • DOI

      10.1016/j.bbrc.2014.12.016

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25136722, KAKENHI-PROJECT-25460350, KAKENHI-PROJECT-26460351, KAKENHI-PROJECT-26893317, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-25221306
  • [Journal Article] Regulation of blood pressure and renal electrolyte balance by Cullin-RING ligases.2014

    • Author(s)
      Uchida S.
    • Journal Title

      Curr Opin Nephrol Hypertens.

      Volume: 23 Pages: 487-493

    • DOI

      10.1097/mnh.0000000000000049

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] WNK4 is the major WNK kinase positively regulating NCC in the mouse kidney.2014

    • Author(s)
      Takahashi D, Mori T, Nomura N, Khan MZ, Araki Y, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S
    • Journal Title

      Biosci Rep.

      Volume: 34 (3) Pages: 195-205

    • DOI

      10.1042/bsr20140047

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-26670428
  • [Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.2014

    • Author(s)
      Susa K, Sohara E, Rai T, Zeniya M, Mori Y, Mori T, Chiga M, Nomura N, Nishida H, Takahashi D, Isobe K, Inoue Y, Takeishi K, Takeda N, Sasaki S, Uchida S
    • Journal Title

      Hum Mol Genet.

      Volume: 23 (19) Pages: 5052-5060

    • DOI

      10.1093/hmg/ddu217

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-26860628, KAKENHI-PROJECT-221S0001
  • [Journal Article] Aberrant Glycosylation and Localization of Polycystin-1 Cause Polycystic Kidney in an AQP11 Knockout Model2014

    • Author(s)
      Inoue Y, Sohara E, Kobayashi K, Chiga M, Rai T, Ishibashi K, Horie S, Su X, Zhou J, Sasaki S, Uchida S.
    • Journal Title

      J Am Soc Nephrol

      Volume: 25 Pages: 2789-2799

    • DOI

      10.1681/asn.2013060614

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591243, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-26670428
  • [Journal Article] Selective loss of parvalbumin-positive GABAergic interneurons in the cerebral cortex of maternally stressed Gad1-heterozygous mouse offspring.2014

    • Author(s)
      Uchida, T., Furukawa, T., Iwata, S., Yanagawa, Y. and *Fukuda, A.
    • Journal Title

      Translational Psychiatry

      Volume: 4

    • DOI

      10.1038/tp.2014.13

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293052, KAKENHI-PUBLICLY-26110705, KAKENHI-PROJECT-26670512
  • [Journal Article] Regulation of with-no-lysine kinase signaling by Kelch-like proteins.2014

    • Author(s)
      Uchida S, Sohara E, Rai T, Sasaki S
    • Journal Title

      Biol Cell.

      Volume: 106(2) Pages: 45-56

    • DOI

      10.1111/boc.201300069

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.2013

    • Author(s)
      Chu PY, Cheng CJ, Wu YC, Fang YW, Chau T, Uchida S, Sasaki S, Yang SS, Lin SH.
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0072969

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II.2013

    • Author(s)
      Zeniya M, Sohara E, Kita S, Iwamoto T, Susa K, Mori T, Oi K, Chiga M, Takahashi D, Yang SS, Lin SH, Rai T, Sasaki S, Uchida S
    • Journal Title

      Hypertension

      Volume: 62(5) Pages: 872-8

    • DOI

      10.1161/hypertensionaha.113.01543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-23590319, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PUBLICLY-25136722, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25460350, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-25860670
  • [Journal Article] KLHL2 interacts with and ubiquitinates WNK kinases.2013

    • Author(s)
      Takahashi D, Mori T, Wakabayashi M, Mori Y, Susa K, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 437(3) Pages: 457-62

    • DOI

      10.1016/j.bbrc.2013.06.104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] Phosphorylation regulates NCC stability and transporter activity in vivo.2013

    • Author(s)
      Yang SS, Fang YW, Tseng MH, Chu PY, Yu IS, Wu HC, Lin SW, Chau T, Uchida S, Sasaki S, Lin YF, Sytwu HK, Lin SH.
    • Journal Title

      J Am Soc Nephrol.

      Volume: 24 Pages: 1587-97

    • DOI

      10.1681/asn.2012070742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] Development of enzyme-linked immunosorbent assays for urinary thiazide-sensitive Na-Cl cotransporter (NCC) measurement.2013

    • Author(s)
      Isobe K, Mori T, Asano T, Kawaguchi H, Nonoyama S, Kumagai N, Kamada F, Morimoto T, Hayashi M, Sohara E, Rai T, Sasaki S, Uchida S.
    • Journal Title

      Am J Physiol Renal Physiol.

      Volume: 305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670406
  • [Journal Article] Development of enzyme-linked immunosorbent assays for urinary thiazide-sensitive Na-Cl cotransporter (NCC) measurement.2013

    • Author(s)
      Isobe K, Mori T, Asano T, Kawaguchi H, Nonoyama S, Kumagai N, Kamada F, Morimoto T, Hayashi M, Sohara E, Rai T, Sasaki S, Uchida S.
    • Journal Title

      Am J Physiol Renal Physiol.

      Volume: 305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Journal Article] Immunolocalization and translocation of aquaporin-5 water channel in sweat glands2013

    • Author(s)
      Inoue R, Sohara E, Rai T, Satoh T, Yokozeki H, Sasaki S, Uchida S.
    • Journal Title

      J Dermatol Sci

      Volume: 70 Pages: 26-33

    • DOI

      10.1016/j.jdermsci.2013.01.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-24659413, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] ImpairedKLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension2013

    • Author(s)
      Wakabayashi M, Mori T, Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, NomuraN, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S
    • Journal Title

      Cell Rep

      Volume: 3(3) Pages: 858-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Decrease of WNK4 ubiquitination by disease-causing mutations of KLHL3 through different molecular mechanisms.2013

    • Author(s)
      Mori Y, Wakabayashi M, Mori T, Araki Y, Sohara E, Rai T, Sasaki S, Uchida S
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 439(1) Pages: 30-4

    • DOI

      10.1016/j.bbrc.2013.08.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy2013

    • Author(s)
      Mori, T.; Kikuchi, E.; Watanabe, Y.; Fujii, S.; Ishigami-Yuasa, M.; Kagechika, H.; Sohara, E.; Rai, T.; Sasaki, S.; Uchida, S.
    • Journal Title

      Biochem J

      Volume: 455 Pages: 339-345

    • DOI

      10.1042/bj20130597

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-25670406
  • [Journal Article] Treatment with 17-allylamino-17-demethoxygeldanamycin ameliorated symptoms of Bartter syndrome type IV caused by mutated Bsnd in mice.2013

    • Author(s)
      Nomura N, Kamiya K, Ikeda K, Yui N, Chiga M, Sohara E, Rai T, Sasaki S, Uchida S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 441 Pages: 544-49

    • DOI

      10.1016/j.bbrc.2013.10.129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-24659413, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25293351, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-25670721
  • [Journal Article] Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension2013

    • Author(s)
      Wakabayashi M
    • Journal Title

      Cell Reports.

      Volume: 28 Pages: 858-68

    • DOI

      10.1016/j.celrep.2013.02.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047, KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24659413, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
  • [Journal Article] Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination2012

    • Author(s)
      Hossain Khan MZ, Sohara E, Ohta A, ChigaM, Inoue Y, Isobe K, Wakabayashi M, Oi K, Rai T, Sasaki S, Uchida S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 425 Pages: 456-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates itsubiquitination2012

    • Author(s)
      Hossain Khan MZ, Sohara E, Ohta A, Chiga M, Inoue Y, Isobe K, Wakabayashi M, Oi K, Rai T, Sasaki S, Uchida S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 425 Pages: 456-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Does a β2-adrenergicreceptor-WNK4-Na-Cl co-transporter signal cascade exist in the in vivo kidney?2012

    • Author(s)
      Uchida S, Chiga M, Sohara E, Rai T, Sasaki S
    • Journal Title

      Nat.Med

      Volume: 18 Pages: 1324-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] A new role for aquaporin 7 in insulin secretion2012

    • Author(s)
      Louchami K, Best L, Brown P, Virreira M, Hupkens E, Perret J, Devuyst O, Uchida S, Delporte C, Malaisse WJ, Beauwens R, SenerA
    • Journal Title

      Cell Physiol. Biochem

      Volume: 29 Pages: 65-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells2012

    • Author(s)
      Hara-Chikuma M, Sugiyama Y, Kabashima K, Sohara E, Uchida S, Sasaki S, Inoue S, Miyachi Y
    • Journal Title

      FASEB J

      Volume: 26 Pages: 211-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice2012

    • Author(s)
      Nishida H, Sohara E, Nomura N, Chiga M, Alessi DR, Rai T, Sasaki S, Uchida S
    • Journal Title

      Hypertension

      Volume: 60 Pages: 981-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney2012

    • Author(s)
      Naguro I, Umeda T, Kobayashi Y, Maruyama J, Hattori K, Shimizu Y, Kataoka K, Kim-Mitsuyama S, Uchida S, Vandewalle A, Noguchi T, Nishitoh H, Matsuzawa A, Takeda K, Ichijo H
    • Journal Title

      Nat. Commun

      Volume: 3 Pages: 1285-1285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Accumulation of autofluorescent storage material in brain is accelerated byischemia in chloride channel 3gene-deficient mice2012

    • Author(s)
      Ohtaki H, Ohara K, Song D, Miyamoto K, Tsumuraya T, Yofu S, Dohi K, Tanabe S, Sasaki S, Uchida S, Matsunaga M, Shioda S
    • Journal Title

      J. Neurosci. Res

      Volume: 90 Pages: 2163-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Phosphatidylinositol 3-kinase/Akt signaling pathway activates theWNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice2012

    • Author(s)
      Nishida H, Sohara E, Nomura N, Chiga M, Alessi DR, Rai T, Sasaki S, Uchida S
    • Journal Title

      Hypertension

      Volume: 60 Pages: 981-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Does a β2-adrenergic receptor-WNK4-Na-Cl co-transporter signal cascade exist in the in vivo kidney?2012

    • Author(s)
      Uchida S, Chiga M, Sohara E, Rai T, Sasaki S
    • Journal Title

      Nat. Med

      Volume: 18 Pages: 1324-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] A new role for aquaporin 7 in insulinsecretion2012

    • Author(s)
      Louchami K, Best L, Brown P, Virreira M, Hupkens E, Perret J, Devuyst O, Uchida S, Delporte C, Malaisse WJ, Beauwens R, Sener A
    • Journal Title

      Cell Physiol. Biochem

      Volume: 29 Pages: 65-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] WNK-OSR1/SPAK-NCC signal cascade has circadian rhythmdependent on aldosterone2012

    • Author(s)
      Susa K, Sohara E, Isobe K, Chiga M, Rai T, Sasaki S, Uchida S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 427 Pages: 743-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo2012

    • Author(s)
      Oi K, Sohara E, Rai T, Misawa M, ChigaM, Alessi DR, Sasaki S, Uchida S
    • Journal Title

      Biol.Open

      Volume: 1 Pages: 120-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Accumulation of autofluorescent storage material in brain is accelerated by ischemia in chloride channel 3 gene-deficient mice2012

    • Author(s)
      Ohtaki H, Ohara K, Song D, Miyamoto K, Tsumuraya T, Yofu S, Dohi K, Tanabe S,Sasaki S, Uchida S, Matsunaga M, Shioda S
    • Journal Title

      J. Neurosci. Res

      Volume: 90 Pages: 2163-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] A minor role of WNK3 in regulating phosphorylation ofrenal NKCC2 and NCC co-transporters in vivo2012

    • Author(s)
      Oi K, Sohara E, Rai T, Misawa M, Chiga M, Alessi DR, Sasaki S, Uchida S
    • Journal Title

      Biol.Open

      Volume: 1 Pages: 120-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Does a β(2)-adrenergic receptor - WNK4 - Na-Cl co-transporter signal cascade exist in the in vivo kidney?2012

    • Author(s)
      Uchida S
    • Journal Title

      Nat Med

      Volume: 18 Pages: 1324-1325

    • DOI

      10.1038/nm.2809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047, KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-23659439, KAKENHI-PROJECT-24659413, KAKENHI-PROJECT-24790836
  • [Journal Article] Involvement of aquaporin-7 inthe cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells2012

    • Author(s)
      Hara-Chikuma M, Sugiyama Y, Kabashima K, Sohara E, Uchida S, Sasaki S, Inoue S, Miyachi Y
    • Journal Title

      FASEB J

      Volume: 26 Pages: 211-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney2012

    • Author(s)
      Naguro I, Umeda T, Kobayashi Y, MaruyamaJ, Hattori K, Shimizu Y, Kataoka K,Kim-Mitsuyama S, Uchida S, Vandewalle A, Noguchi T, Nishitoh H, Matsuzawa A, Takeda K, Ichijo H
    • Journal Title

      Nat. Commun

      Volume: 3 Pages: 1285-1285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Effect of heterozygousdeletion of WNK1 on the WNK-OSR1/SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels2012

    • Author(s)
      Susa K, Kita S, Iwamoto T, Yang SS, LinSH, Ohta A, Sohara E, Rai T, Sasaki S, Alessi DR, Uchida S
    • Journal Title

      Clin. Exp. Nephrol

      Volume: 16 Pages: 530-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Immunolocalization of WNK4 in mouse kidney2011

    • Author(s)
      Ohno M, Uchida K, Ohashi T, Nitta K, Ohta A, Chiga M, Sasaki S, Uchida S
    • Journal Title

      Histochem. Cell Biol

      Volume: 136 Pages: 25-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney2011

    • Author(s)
      Sohara E, Rai T, Yang SS, Ohta A, NaitoS, Chiga M, Nomura N, Lin SH, VandewalleA, Ohta E, Sasaki S, Uchida S
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Calcium and calcimimetics regulate paracellular Na+transport in the thin ascending limb of Henle's loop in mouse kidney2011

    • Author(s)
      Sugawara, N., Morimoto, T., Farajov, E. I., Kumagai, N., Aslanova, U. F. Rai, T., Uchida, S., Sasaki, S., Tsuchiya, S., Kondo, Y
    • Journal Title

      Pflugers Arch

      Volume: 460(1) Pages: 197-205

    • Data Source
      KAKENHI-PROJECT-19390279
  • [Journal Article] Generation and analyses of R8L barttin knockin mouse2011

    • Author(s)
      Nomura N, Tajima M, Sugawara N, Morimoto T, Kondo Y, Ohno M, Uchida K, Mutig K, Bachmann S, Soleimani M, Ohta E, Ohta A, Sohara E, Okado T, Rai T, Jentsch TJ, Sasaki S, UchidaS
    • Journal Title

      Am. J. Physiol. Renal. Physiol

      Volume: 301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Generation and analyses of R8L barttin knockin mouse2011

    • Author(s)
      Nomura N, Tajima M, Sugawara N, Morimoto T, Kondo Y, Ohno M, Uchida K, Mutig K, Bachmann S, Soleimani M, Ohta E, Ohta A, Sohara E, Okado T, Rai T, JentschTJ, Sasaki S, Uchida S
    • Journal Title

      Am. J. Physiol. Renal. Physiol

      Volume: 301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCCco-transporters in vivo2011

    • Author(s)
      Oi K, Sohara E, Rai T, Misawa M, ChigaM, Alessi DR, Sasaki S, Uchida S
    • Journal Title

      Biology Open

      Volume: 1(2) Pages: 120-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on theWNK-OSR1/SPAK kinase cascade2011

    • Author(s)
      Chiga M, Rafiqi FH, Alessi DR, Sohara E, Ohta A, Rai T, Sasaki S, Uchida S
    • Journal Title

      J. Cell Sci

      Volume: 124 Pages: 1391-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on theWNK-OSR1/SPAK kinase cascade2011

    • Author(s)
      Chiga M, Rafiqi FH, Alessi DR, Sohara E, Ohta A, Rai T, Sasaki S, Uchida S
    • Journal Title

      J. Cell Sci

      Volume: 124 Pages: 1391-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Dexamethasone increases the phosphorylation of nephrin in cultured podocytes2011

    • Author(s)
      Ohashi T, Uchida K, Uchida S, Sasaki S, Nitta K
    • Journal Title

      Clin. Exp. Nephrol

      Volume: 15 Pages: 688-93

    • NAID

      10030340996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Regulation of WNK1 kinase by extracellular potassium2011

    • Author(s)
      Naito S, Ohta A, Sohara E, Ohta E, Rai T, Sasaki S, Uchida S
    • Journal Title

      Clin. Exp. Nephrol

      Volume: 15 Pages: 195-202

    • NAID

      10029005115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1deficiency manifests hypotension and Bartter-like syndrome2011

    • Author(s)
      Lin SH, Yu IS, Jiang ST, Lin SW, Chu P, Chen A, Sytwu HK, Sohara E, Uchida S, Sasaki S, Yang SS
    • Journal Title

      Proc. Natl. Acad. Sci. U S A

      Volume: 108 Pages: 17538-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Dexamethasone increases the phosphorylation of nephrin in culturedpodocytes2011

    • Author(s)
      Ohashi T, Uchida K, Uchida S, SasakiS, Nitta K
    • Journal Title

      Clin. Exp. Nephrol

      Volume: 15 Pages: 688-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Journal Article] Immunolocalization of WNK4 in mouse kidney2011

    • Author(s)
      Ohno M, Uchida K, Ohashi T, Nitta K, Ohta A, Chiga M, Sasaki S, UchidaS
    • Journal Title

      Histochem. Cell Biol

      Volume: 136 Pages: 25-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1deficiency manifests hypotension and Bartter-like syndrome2011

    • Author(s)
      Lin SH, Yu IS, Jiang ST, Lin SW, Chu P, Chen A, Sytwu HK, Sohara E, Uchida S, Sasaki S, Yang SS
    • Journal Title

      Proc. Natl. Acad. Sci. U S A

      Volume: 108 Pages: 17538-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Generation and analyses of R8L barttin knockin mouse2011

    • Author(s)
      Nomura, N., Tajima, M., Sugawara, N., Morimoto, T., Kondo, Y., Ohno, M., Uchida, K., Mutig, K., Bachmann, S., Soleimani, M., Ohta, E., Ohta, A., Sohara, E., Okado, T., Rai, T., Jentsch, T. J., Sasaki, S., Uchida, S
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 301(2)

    • Data Source
      KAKENHI-PROJECT-19390279
  • [Journal Article] Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney2011

    • Author(s)
      Sohara E, Rai T, Yang SS, Ohta A, NaitoS, Chiga M, Nomura N, Lin SH, Vandewalle A, Ohta E, Sasaki S, Uchida S
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney2010

    • Author(s)
      Talati G, Ohta A, Rai T, Sohara E, Naito S, Vandewalle A, Sasaki S, Uchida S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 393 Pages: 844-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Calcium and calcimimetics regulate paracellular Na+ transport in the thin ascending limb of Henle's loop in mouse kidney2010

    • Author(s)
      Sugawara N, Morimoto T, Farajov EI, Kumagai N, Aslanova UF, Rai T, Uchida S, Sasaki S, Tsuchiya S, Kondo Y
    • Journal Title

      Pflugers Arch

      Volume: 460 Pages: 197-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Pathophysiological roles of WNK kinases in the kidney2010

    • Author(s)
      Uchida S
    • Journal Title

      Pflugers Arch

      Volume: 460 Pages: 695-702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice2010

    • Author(s)
      Yang SS, Hsu YJ, Chiga M, Rai T, Sasaki S, Uchida S, Lin SH
    • Journal Title

      Endocrinology

      Volume: 151 Pages: 1829-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Generation and analysis of the thiazide-sensitive Na+ -Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome2010

    • Author(s)
      Yang SS, Lo YF, Yu IS, Lin SW, Chang TH, Hsu YJ, Chao TK, Sytwu HK, Uchida S, Sasaki S, Lin SH
    • Journal Title

      Hum. Mutat

      Volume: 31 Pages: 1304-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Pathophysiological roles of WNK kinases in the kidney.2010

    • Author(s)
      Uchida S.
    • Journal Title

      Pflugers Arch. 460

      Pages: 695-702

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney.2010

    • Author(s)
      Talati G, Ohta A, Rai T, Sohara E, Naito S, Vandewalle A, Sasaki S, Uchida S.
    • Journal Title

      Biochem. Biophys. Res.Commun. 393

      Pages: 844-848

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction2010

    • Author(s)
      Yang SS, Lo YF, Wu CC, Lin SW, Yeh CJ, Chu P, Sytwu HK, Uchida S, Sasaki S, Lin SH
    • Journal Title

      J. Am. Soc. Nephrol

      Volume: 21 Pages: 1868-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Phosphorylation of aquaporin-2 regulates its water permeability.2010

    • Author(s)
      Eto K, Noda Y, Horikawa S, Uchida S, Sasaki S.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 40777-40784

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation2010

    • Author(s)
      Mutig K, Saritas T, Uchida S, Kahl T,Borowski T, Paliege A, Bohlick A, Bleich M, Shan Q, Bachmann S
    • Journal Title

      Am. J. Physiol. Renal Physiol

      Volume: 298 Pages: 502-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Pathophysiological roles of WNK kinases in the kidney.2010

    • Author(s)
      Uchida s
    • Journal Title

      Pflugers Arch.

      Volume: 460 Pages: 695-702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Phosphorylation of aquaporin-2 regulates its water permeability2010

    • Author(s)
      Eto K, Noda Y, Horikawa S, Uchida S, Sasaki S
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 40777-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Expression and phosphorylation of the Na^+-Clcotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am. J.Physiol.2009

    • Author(s)
      Vallon V, Schroth J, Lang F, Kuhl D, Uchida S.
    • Journal Title

      Renal Physiol. 297

      Pages: 704-712

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis2009

    • Author(s)
      Ohta E, Itoh T, Nemoto T, Kumagai J, Ko SB, Ishibashi K, Ohno M, Uchida K, Ohta A, Sohara E, Uchida S, Sasaki S, Rai T.
    • Journal Title

      Am.J.Physiol.Cell Physiol. 297

      Pages: 1368-78

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] FAPP2 is required for aquaporin-2 apical sorting at trans-Golgi network in polarized MDCK cells.2009

    • Author(s)
      Yui N, Okutsu R, Sohara E, Rai T, Ohta A, Noda Y, Sasaki S, Uchida S.
    • Journal Title

      Am.J.Physiol.Cell Physiol. 297

      Pages: 1389-1396

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.2009

    • Author(s)
      Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S.
    • Journal Title

      Hum.Mol.Genet. 18

      Pages: 3978-86

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Aquaporin-2 regulates cell volume recovery via tropomyosin2009

    • Author(s)
      Li YH, Eto K, Horikawa S, Uchida S, Sasaki S, Li XJ, Noda Y
    • Journal Title

      Int. J. Biochem. Cell Biol

      Volume: 41 Pages: 2466-2476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure2009

    • Author(s)
      Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S.
    • Journal Title

      Hum.Mol.Genet. 18

      Pages: 3978-86

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo isregulated by dietary salt, potassium, and SGK12009

    • Author(s)
      Vallon V, Schroth J, Lang F, Kuhl D, Uchida S
    • Journal Title

      Am. J. Physiol. Renal Physiol

      Volume: 297 Pages: 704-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis.2009

    • Author(s)
      Ohta E, Itoh T, Nemoto T, Kumagai J, Ko SB, Ishibashi K, Ohno M, Uchida K, Ohta A, Sohara E, Uchida S, Sasaki S, Rai T.
    • Journal Title

      Am. J. Physiol. Cell Physiol. 297

      Pages: 1368-78

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis2009

    • Author(s)
      Ohta E, Itoh T, Nemoto T, Kumagai J, Ko SB, Ishibashi K, Ohno M, Uchida K, Ohta A, Sohara E, Uchida S, Sasaki S, Rai T
    • Journal Title

      Am. J. Physiol. Cell Physiol

      Volume: 297 Pages: 1368-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] FAPP2 is required for aquaporin-2 apical sorting at trans-Golgi network in polarized MDCK cells2009

    • Author(s)
      Yui N, Okutsu R, Sohara E, Rai T, Ohta A, Noda Y, Sasaki S, Uchida S.
    • Journal Title

      Am.J.Physiol.Cell Physiol. 297

      Pages: 1389-1396

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] FAPP2 is required for aquaporin-2 apical sorting attrans-Golgi network in polarized MDCK cells2009

    • Author(s)
      Yui N, Okutsu R, Sohara E, Rai T, OhtaA, Noda Y, Sasaki S, Uchida S
    • Journal Title

      Am. J. Physiol. Cell Physiol

      Volume: 297 Pages: 1389-1396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Function of aquaporin-7 in the kidney and the male reproductive system2009

    • Author(s)
      Sohara E, Uchida S, Sasaki S
    • Journal Title

      Handb ExpPharmacol

      Pages: 219-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] FAPP2 is required for aquaporin-2 apical sorting at trans-Golgi network in polarized MDCK cells.2009

    • Author(s)
      Yui N, Okutsu R, Sohara E, Rai T, Ohta A, Noda Y, Sasaki S, Uchida S.
    • Journal Title

      Am. J. Physiol. Cell Physiol. 297

      Pages: 1389-1396

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Targeted disruption of the Wnk4 genedecreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure2009

    • Author(s)
      Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S
    • Journal Title

      Hum. Mol. Genet

      Volume: 18 Pages: 3978-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.2009

    • Author(s)
      Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S.
    • Journal Title

      Hum. Mol. Genet. 18

      Pages: 3978-86

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] AKAP220 colocalizes with AQP2 in the inner medullary collecting ducts2008

    • Author(s)
      Okutsu R, Rai T, Kikuchi A, Ohno M, Uchida K, Sasaki S, Uchida S
    • Journal Title

      Kidney Int

      Volume: 74 Pages: 1429-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] AKAP220 colocalizes with AQP2 in the inner medullary collecting ducts.2008

    • Author(s)
      Okutsu R, Rai T, Kikuchi A, Ohno M, Uchida K, Sasaki S, Uchida S.
    • Journal Title

      Kidney Int. 74

      Pages: 1429-1433

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Intracellular ClC-3 chloride channels promote bone resorption in vitro through organelle acidification in mouse osteoclasts2008

    • Author(s)
      Okamoto F, Kajiya H, Toh K, Uchida S, Yoshikawa M, Sasaki S, Kido MA, Tanaka T, Okabe K
    • Journal Title

      Am. J .Physiol. Cell Physiol

      Volume: 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.2008

    • Author(s)
      Chiga M, Rai T, Yang SS, Ohta A, Takizawa T, Sasaki S, Uchida S.
    • Journal Title

      Kidney Int. 74

      Pages: 1403-1409

    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.2008

    • Author(s)
      Chiga M, Rai T, Yang S-S, Ohta A, Takizawa T, Sasaki S, Uchida S.
    • Journal Title

      Kidney Int. 74

      Pages: 1403-1409

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone2008

    • Author(s)
      Chiga M, Rai T, Yang SS, Ohta A, Takizawa T, Sasaki S, Uchida S
    • Journal Title

      Kidney Int

      Volume: 74 Pages: 1403-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Journal Article] Molecular pathogenesis of pseudohypoaldosteronism type II : generation and analysis of a Wnk4 D561A/+ knock-in mouse model2007

    • Author(s)
      Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin S-H, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.
    • Journal Title

      Cell Metab 5

      Pages: 331-344

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] Molecular pathogenesis of pseudohypoaldosteronism type II : generation and analysis of a Wnk4(D561A/+) knockin mouse model2007

    • Author(s)
      Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.
    • Journal Title

      Cell Metab 5(5)

      Pages: 331-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Journal Article] Barttin binds to the outer lateral surface of the C1C-K2 chloride channel2007

    • Author(s)
      Tajima M, Hayama A, Rai T, Sasaki S, Uchida S.
    • Journal Title

      Biochem Biophys Res Commun 3 ; 362(4)

      Pages: 858-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Journal Article] Molecular pathogenesis of pseudohypoaldosteronism type II : generation and analysis of a Wnk4 (D 561A/+) knockin mouse model2007

    • Author(s)
      Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.
    • Journal Title

      Cell Metab 5 (5)

      Pages: 331-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390279
  • [Journal Article] Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4 D561A/+ knock-in mouse model.2007

    • Author(s)
      Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin S-H, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.
    • Journal Title

      Cell Metab 5

      Pages: 331-344

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Molecular pathogenesis of pseudohypoaldosteronism type II : generation and analysis of a Wnk4(D561A/+) knockin mouse model2007

    • Author(s)
      Yang, S. S., Morimoto, T., Rai, T., Chiga, M., Sohara, E., Ohno, M., Uchida, K., Lin, S. H., Moriguchi, T., Shibuya, H., Kondo, Y., Sasaki, S., Uchida, S
    • Journal Title

      Cell Metab

      Volume: 5(5) Pages: 331-44

    • Data Source
      KAKENHI-PROJECT-19390279
  • [Journal Article] Morphologic and functional analysis of sperm and testes in aquaporin 7 knockout mice2007

    • Author(s)
      Sohara E, Ueda O, Tachibe T, Hani T, Jishage K, Rai T, Sasaki S, Uchida S.
    • Journal Title

      Fertil Steril 87(3)

      Pages: 671-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Journal Article] Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers.2006

    • Author(s)
      Suzuki T, Rai T, Hayama A, Sohara E, Suda S, Itoh T, Sasaki S, Uchida S
    • Journal Title

      J Cell Physiol 206

      Pages: 792-798

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation2006

    • Author(s)
      Sohara E, Rai T, Yang SS, Uchida K, Nitta K, Horita S, Ohno M, Harada A, Sasaki S, Uchida S.
    • Journal Title

      Proc Natl Acad Sci USA 103

      Pages: 14217-14222

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] The polarized trafficking of the aquaporin-3 water channel is mediated by an N-Terminal Sorting Signal.2006

    • Author(s)
      Rai T, Sasaki S, Uchida S.
    • Journal Title

      Am J Physiol Cell Physiol. 290(1)

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] The polarized trafficking of the aquaporin-3 water channel is mediated by an N-Terminal Sorting Signal2006

    • Author(s)
      Rai T, Sasaki S, Uchida S.
    • Journal Title

      Am J Physiol Cell Physiol. 290(1)

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] The polarized trafficking of the aquaporin-3 water channel is mediated by an N-terminal sorting signal.2006

    • Author(s)
      Rai T, Sasaki S, Uchida S
    • Journal Title

      Am J Physiol Cell Physiol 290(1)

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] The polarized trafficking of the aquaporin-3 water channel is mediated by an N-terminal sorting signal.2006

    • Author(s)
      Rai T, Sasaki S, Uchida S
    • Journal Title

      Am J Physiol Cell Physiol 290(1)

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers.2006

    • Author(s)
      Suzuki T, Rai T, Hayama A, Sohara E, Suda S, Itoh T, Sasaki S, Uchida S
    • Journal Title

      J Cell Physiol 206

      Pages: 792-798

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation.2006

    • Author(s)
      Sohara E, Rai T, Yang SS, Uchida K, Nitta K, Horita S, Ohno M, Harada A, Sasaki S, Uchida S.
    • Journal Title

      Proc Natl Acad Sci U S A. 103

      Pages: 14217-14222

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Postonatal expression of KLF12 in the inner medullary colleting ducts of kidney and its trans-activation of UT-Al urea transporter promoter2006

    • Author(s)
      Suda S, Rai T, Sohara E, Sasaki S, Uchida S.
    • Journal Title

      Biochem Biophys Res Commun 344

      Pages: 246-252

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Journal Article] ClC-3 Chloride channels facilitate endosomal acidification and chloride accumulation.2005

    • Author(s)
      Hara-Chikuma M, Uchida S, et al.
    • Journal Title

      J Biol Chem 280(2)

      Pages: 1241-1247

    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Function of chloride channels in the kidney.2005

    • Author(s)
      Uchida S et al.
    • Journal Title

      Annu Rev Physiol 67

      Pages: 759-778

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Function of chloride channeils in the kidney.2005

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Annu. Rev. Physiol. 67

      Pages: 759-778

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Mol. Cell Biol 25

      Pages: 7357-7363

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] Progressive adipocyte hypertrophy in aquaporin-7 deficient mice : Adipocyte glycerol permeability as a novel regulator of fat accumulation2005

    • Author(s)
      Hara-Chikuma M, Sohara E, Rai T, Ikawa M, Okabe M, Sasaki S, Uchida S, Verkman AS.
    • Journal Title

      J Biol Chem. 280(16)

      Pages: 15493-15496

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S, Sohara E, Rai T, Ikawa M, Okabe M, Sasaki S
    • Journal Title

      Mol Cell Biol 25

      Pages: 7357-7363

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice2005

    • Author(s)
      Sohara E, Rai T, Miyazaki J, Verkman AS, Sasaki S, Uchida S.
    • Journal Title

      Am J Physiol Renal Physiol. 289(6)

    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Journal Article] ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.2005

    • Author(s)
      Hara-Chikuma M, Yang B, Sonawane ND, Sasaki S, Uchida S, Verkman AS
    • Journal Title

      J Biol Chem 280

      Pages: 1241-1247

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] CIC-3 Chloride channels facilitate endosomal acidification and chloride accumulation.2005

    • Author(s)
      Hara-Chikuma M, Uchida S, et al.
    • Journal Title

      J Biol Chem 280(2)

      Pages: 1241-1247

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Mol Cell Biol 25(16)

      Pages: 7357-7363

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.2005

    • Author(s)
      Sohara E, Rai T, Miyazaki J, Verkman AS, Sasaki S, Uchida S.
    • Journal Title

      Am J Physiol Renal Physiol. 289(6)

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells.2005

    • Author(s)
      Yang S-S, Yamauchi K, Rai T, Hayama A, Sohara E, Suzuki T, Itoh T, Suda S, Sasaki S, Uchida S
    • Journal Title

      Biochem Biophys Res Com 330

      Pages: 410-414

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Defective water and glycerol transportin the proximal tubules of AQP7 knockout mice.2005

    • Author(s)
      Sohara E, Rai T, Miyazaki J, Ikawa M, Okabe M, Verkman A.S., Sasaki S, Uchida S
    • Journal Title

      Am J Physiol Renal Physiol 289

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Impaired urea accumulationin the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S et al.
    • Journal Title

      Mol Cell Biol 25

      Pages: 7357-7363

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Mol Cell Biol 25(16)

      Pages: 7357-7363

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Function of chloride channels in the kidney.2005

    • Author(s)
      Uchida S, Sasaki S
    • Journal Title

      Annu Rev Physiol 67

      Pages: 759-778

    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S, Sohara E, Rai T, Ikawa M, Okabe M, Sasaki S
    • Journal Title

      Mol Cell Biol 25

      Pages: 7357-7363

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells.2005

    • Author(s)
      Yang S-S, Yamauchi K, Rai T, Hayama A, Sohara E, Suzuki T, Itoh T, Suda S, Sasaki S, Uchida S
    • Journal Title

      Biochem Biophys Res Com 330

      Pages: 410-414

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.2005

    • Author(s)
      Hara-Chikuma M, Yang B, Sonawane ND, Sasaki S, Uchida S, Verkman AS
    • Journal Title

      J Biol Chem 280

      Pages: 1241-1247

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Function of chloride channels in the kidney.2005

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Annu Rev Physiol 67

      Pages: 759-778

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Impaired urea accumulationin the inner medulla of mice lacking the urea transporter UT-A2.2005

    • Author(s)
      Uchida S et al.
    • Journal Title

      Mol Cell Biol 25

      Pages: 7357-7363

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Function of chloride channels in the kidney.2005

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Annu Rev Physiol 67

      Pages: 759-778

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Defective water and glycerol transportin the proximal tubules of AQP7 knockout mice.2005

    • Author(s)
      Sohara E, Rai T, Miyazaki J, Ikawa M, Okabe M, Verkman A.S., Sasaki S, Uchida S
    • Journal Title

      Am J Physiol Renal Physiol 289

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Progressive adipocyte hypertrophy in aquaporin-7 deficient mice: Adipocyte glycerol permeability as a novel regulator of fat accumulation.2005

    • Author(s)
      Hara-Chikuma M, Sohara E, Rai T, Ikawa M, Okabe M, Sasaki S, Uchida S, Verkman AS.
    • Journal Title

      J Biol Chem. 280(16)

      Pages: 15493-15496

    • Data Source
      KAKENHI-PROJECT-17081009
  • [Journal Article] Function of chloride channels in the kidney.2005

    • Author(s)
      Uchida S et al.
    • Journal Title

      Annu Rev Physiol 67

      Pages: 759-778

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Function of chloride channels in the kidney.2005

    • Author(s)
      Uchida S, Sasaki S
    • Journal Title

      Annu Rev Physiol 67

      Pages: 759-778

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] 1.Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins.:,2004.2004

    • Author(s)
      Yamauchi K, Uchida S, Sasaki S, et al.
    • Journal Title

      Proc Natl Acad Sci U S A. 101

      Pages: 4690-4694

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] ClC-3-independent, PKC-dependent activity of volume-sensitive Cl- channel in mouse ventricular cardiomyocytes.2004

    • Author(s)
      Gong WQ, Uchida S, Sasaki S et al.
    • Journal Title

      Cell Physiol Biochem 14

      Pages: 213-224

    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins.:, 2004.2004

    • Author(s)
      Yamauchi K, Uchida S, Sasaki S, et al.
    • Journal Title

      Proc Natl Acad Sci U S A. 101

      Pages: 4690-4694

    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] ClC-3-independent, PKC-dependent activity of volume-sensitive Cl- channel in mouse ventricular cardiomyocytes.2004

    • Author(s)
      Gong WQ, Uchida S, Sasaki S et al.
    • Journal Title

      Cell Physiol Biochem 14

      Pages: 213-224

    • Data Source
      KAKENHI-PROJECT-16390241
  • [Journal Article] Isolation of a novel zinc finger repressor that regulates the kidney-specific CLC-K1 promoter.2001

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Kidney Int 60(2)

      Pages: 416-421

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Isolation of a novel zinc finger repressor that regulates the kidney-specific CLC-K1 promoter.2001

    • Author(s)
      Uchida S et al.
    • Journal Title

      Kidney Int 60(2)

      Pages: 416-421

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Transcriptional regulation of the CLC-K1 promoter by myc-associatedzinc finger protein and kidney-enriched Kruppel-like factor, a novel zinc finger repressor.2000

    • Author(s)
      Uchida S et al.
    • Journal Title

      Mol Cell Biol 20(19)

      Pages: 7319-7331

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Journal Article] Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc fingerprotein and kidney-enriched Kruppel-like factor, a novel zinc finger repressor.2000

    • Author(s)
      Uchida S, et al.
    • Journal Title

      Mol Cell Biol 20(19)

      Pages: 7319-7331

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144204
  • [Patent] 化合物又はその塩、医薬、抗利尿薬及びプロテインキナ-ゼA活性化薬2020

    • Inventor(s)
      内田 信一、影近 弘之、安藤 史顕、森 修一
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-097124
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] バソプレシンはPKA活性化を介してuromodulin尿中分泌を促進する2021

    • Author(s)
      七松東, 森崇寧, 安藤史顕, 古荘泰佑, 萬代新太郎, 須佐紘一郎, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第64回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] Alox15 knock-outマウスは、腎臓におけるPGD2の増加を介してCKDの腎障害及び線維化を改善2021

    • Author(s)
      高橋直宏, 蘇原映誠, 有田誠, 菊池寛昭, 安藤史顕, 須佐紘一郎, 萬代新太郎, 森崇寧, 頼建光, 内田信一
    • Organizer
      第64回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] PKA活性化薬は白色脂肪のベージュ化を促進し、高脂肪食負荷マウスで体重増加を抑制する2021

    • Author(s)
      藤木珠美、安藤史顕、萬代新太郎、須佐紘一郎、森崇寧、蘇原映誠、頼建光、内田信一.
    • Organizer
      第64回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] Development of Novel Therapeutic Strategies for Congenital NDI and Other PKA-Related Diseases2020

    • Author(s)
      Ando F, Uchida S
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] TNFαは腎臓でのWNK1分解を抑制して塩分感受性を亢進させる2019

    • Author(s)
      古荘泰佑, 蘇原映誠, 萬代新太郎, 菊池寛昭, 新井洋平, 安藤史顕, 銭谷慕子, 森崇寧, 須佐絋一郎, 磯部清志, 野村尚弘, 岡戸丈和, 頼建光, 内田信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Tolvaptan and Bardoxolone Methyl Synergistically Activate the Nrf2/HO-1 pathway.2019

    • Author(s)
      Fujiki T, Ando F, Mandai S, Isobe K, Susa K, Mori T, Nomura N, Sohara E, Rai T, Uchida S
    • Organizer
      ASN Kidney Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Derivatives of FMP-API-1/27 Robustly Activate AQP2 Water Channels Independently of Vasopressin2019

    • Author(s)
      Ando F, Yui N, Mandai S, isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S
    • Organizer
      ASN Kidney Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] Derivatives of FMP-API-1/27 Robustly Activate AQP2 Water Channels Independently of Vasopressin.2019

    • Author(s)
      Ando F, Yui N, Mandai S, isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S
    • Organizer
      ASN Kidney Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Renal TNFα activates WNK phosphorylation cascade and contributes to salt-sensitive hypertension in CKD2019

    • Author(s)
      Furusho T, Mandai S, Kikuchi H, Takahashi N, Fujimaru T, Hashimoto H, Arai Y, Ando F, Mori T, Susa K, Isobe K, Nomura N, Okado T, Rai T, Yamamoto K, Uchida S, Sohara E
    • Organizer
      ASN Kidney Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] 低タンパク食はAMPKのAMP/ATP比感知障害改善を介して腎保護効果を発揮する2019

    • Author(s)
      菊池寛昭, 蘇原映誠, 野村尚弘, 森崇寧, 頼建光, 内田信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] PKA活性化薬の開発と先天性腎性尿崩症治療への応用2019

    • Author(s)
      安藤 史顕, 磯部 清志, 森 崇寧, 須佐 紘一郎, 野村 尚弘, 蘇原 映誠, 頼 建光, 内田 信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] AMPK activation bypassing AMP sensing mechanism is a novel therapeutic strategy for chronic kidney disease2019

    • Author(s)
      Kikuchi H, Sohara E, Nomura N, Mori T, Minamishima YA, Takahashi N, Furusho T, Ando F, Isobe K, Susa K, Rai T, Uchida S
    • Organizer
      ASN Kidney Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] PKA活性化薬の開発と先天性腎性尿崩症治療への応用2019

    • Author(s)
      安藤史顕, 磯部清志, 森崇寧, 須佐紘一郎, 野村尚弘, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] トルバプタンはPERKのリン酸化を介してNrf2/HO-1を活性化する2019

    • Author(s)
      藤木珠美, 安藤史顕, 磯部清志, 須佐紘一郎, 森崇寧, 野村尚弘, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] タクロリムスはNCCのリン酸化を亢進し4型Bartter症候群の症状を改善する。2019

    • Author(s)
      松浦喜明, 野村尚弘, 正田若菜, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] NCX1を介したNCCの脱リン酸化と尿中カリウム排泄機構の解明2019

    • Author(s)
      正田若菜, 野村尚弘, 安藤史顕, 田頭秀章, 岩本隆宏, 太田哲人, 磯部清志, 森崇寧, 須佐紘一郎, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] 先天性腎性尿崩症の新規治療薬の開発2019

    • Author(s)
      安藤 史顕, 内田 信一
    • Organizer
      第54回日本小児腎臓病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01049
  • [Presentation] Genomic Background of Adults with Suspected Ciliopathy on Renal Biopsy.2018

    • Author(s)
      Fujimaru T, Mori T, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Nagatsuji K, Nagahama K, Mishima E, Mochizuki T, Sekine A, Hoshino J, Ubara Y, Uchida S, Sohara E
    • Organizer
      The 52nd Annual Meeting of American Society of Nephrology, Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] WNK1キナーゼはFOXO4の細胞核内局在,転写活性を調節し,骨格筋肥大を制御する2018

    • Author(s)
      萬代 新太郎, 森 崇寧, 野村 尚弘, 古荘 泰佑, 新井 洋平, 菊池 寛昭, 佐々木 絵美, 蘇原 映誠, 頼 建光, 内田 信一
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] WNK1はマクロファージにおいてLPS誘導性サイトカイン産生を抑制する2018

    • Author(s)
      新井 洋平, 蘇原 映誠, 浅野 謙一, 田中 正人, 頼 建光, 内田 信一
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Amelioration of Renal Fibrosis and Tubulointerstitial Damage in Fat-1 Transgenic CKD Mice by Compensation of Decreased Omega-3 Fatty Acids in the Kidney2018

    • Author(s)
      Takahashi N, Kikuchi H, Ishihara T, Arita M, Furusho T, Ando F, Mori T, Isobe K, Susa K, Nomura N, Rai T, Uchida S, Sohara E
    • Organizer
      The 52nd Annual Meeting of American Society of Nephrology, Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Role of ClC-K and Barttin in Low-Potassium induced Sodium-Chloride Cotransporter Activation and Hypertension in Mouse Kidney2018

    • Author(s)
      Naohiro Nomura, Wakana Shoda, Yuanlong Wang, Daiei Takahashi, Moko Zeniya, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
    • Organizer
      ISN Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 高カリウム負荷によるナトリウム-クロライド共輸送体の脱リン酸化機構の解明2018

    • Author(s)
      正田 若菜, 野村 尚弘, 安藤 史顕, 磯部 清志, 森 崇寧, 蘇原 映誠, 頼 建光, 内田 信一
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] 腎臓病領域における希少疾患と指定難病 尿細管疾患領域における希少難病のトランスレーショナルリサーチ2018

    • Author(s)
      内田 信一
    • Organizer
      第61回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] 家族歴のない成人多発性腎嚢胞患者における網羅的遺伝子解析を用いた遺伝子診断と臨床所見の検討2018

    • Author(s)
      藤丸拓也, 森崇寧, 関根章成, 萬代新太郎, 千賀宗子, 菊池寛昭, 安藤史顕, 森雄太郎, 野村尚弘, 飯盛聡一郎, 内藤省太郎, 岡戸丈和, 頼建光, 星野純一, 乳原善文, 蘇原映誠, 内田信一
    • Organizer
      第28回バゾプレシン研究会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] WNK1-OSR1/SPAK-NCCシグナルの亢進が慢性腎臓病モデルマウスの塩分感受性高血圧に関与する2018

    • Author(s)
      古荘 泰佑, 蘇原 映誠, 萬代 新太郎, 菊池 寛昭, 銭谷 慕子, 野村 尚弘, 森 崇寧, 頼 建光, 内田 信一
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Association between Body Mass Index and In-hospital Mortality in Emergently Hospitalized Dialysis-Independent CKD Patients; A Nationwide Retrospective Cohort Study in Japan2018

    • Author(s)
      Hiroaki Kikuchi, Eiichiro Kanda, Fumiaki Ando, Hidehiko Sato, Kiyoshi Isobe, Takayasu Mori, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Eisei Sohara, Tomokazu Okado, Shinichi Uchida, Kiyohide Fushimi and Tatemitsu Rai
    • Organizer
      ISN Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Genomic diagnosis of adult polycystic kidney disease with no family history2018

    • Author(s)
      Takuya Fujimaru, Takayasu Mori, Akinari Sekine, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Soichiro Iimori, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Junichi Hoshino, Yoshifumi Ubara, Shinichi Uchida, Eisei Sohara
    • Organizer
      ISN Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] WNK1-SPAK-NCC signaling cascade is involved in salt sensitive hypertension induced by aristolochic acid nephropathy.2018

    • Author(s)
      Furusho T, Sohara E, Mandai S, Kikuchi H, Ando F, Zeniya M, Mori T, Nomura N, Rai T, Uchida S
    • Organizer
      The 52nd Annual Meeting of American Society of Nephrology, Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] メトホルミンは腎NCCのリン酸化を低下させ塩分排泄を促進する2018

    • Author(s)
      橋本 博子, 蘇原 映誠, 野村 尚宏, 正田 若菜, 磯部 清志, 菊池 寛昭, 安藤 史顕, 森 崇寧, 頼 建光, 内田 信一
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] Tolvaptan activates Nrf2/HO-1 pathway through PERK phosphorylation2018

    • Author(s)
      Fujiki T, Ando F, Isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S
    • Organizer
      The 52nd Annual Meeting of American Society of Nephrology, Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19534
  • [Presentation] 新規腎線維化改善薬としてのbortezomibの検討2017

    • Author(s)
      銭谷慕子, 森崇寧, 油井直史, 野村尚弘, 千賀宗子, 高橋大栄, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Translational researches in the field of water and electrolyte disorders2017

    • Author(s)
      Shinichi Uchida
    • Organizer
      The annual meeting of the American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] KLHL2は腎臓でWNK4蛋白の分解を行う2017

    • Author(s)
      笠木祐里,蘇原映誠,相田知海,高橋大栄,西田秀範,野村尚弘,銭谷慕子,森崇寧,佐々木絵美,安藤史顕,頼建光,内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Generation and Analysis of KLHL2 Knockout Mice2017

    • Author(s)
      Yuri Kasagi, Daiei Takahashi, Tomomi Aida, Hidenori Nishida, Naohiro Nomura, Moko Zeniya, Takayasu Mori, Emi Sasaki, Fumiaki Ando, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
    • Organizer
      The 50th Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] WNK4 Deletion Inhibits Adipogenesis In Vitro and In Vivo2017

    • Author(s)
      Daiei Takahashi, Shinichi Uchida
    • Organizer
      The 50th Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 変異CUL3によるPHAIIの発症にはKLHL3の発現低下が関与する2017

    • Author(s)
      吉田紗矢香, 蘇原映誠, 荒木雄也, 笠木祐里, 佐々木絵美, 須佐紘一郎, 森崇寧, 井上佑一, 磯部清志, 頼建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Role of ClC-K and Barttin in Low-Potassium induced Sodium-Chloride Cotransporter Activation and Hypertension in Mouse Kidney2017

    • Author(s)
      Naohiro Nomura, Wakana Shoda, Yuanlong Wang, Daiei Takahashi, Moko Zeniya, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
    • Organizer
      The 50th Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Decreased protein expression of KLHL3 is involved in the pathogenesis of PHAII caused by CUL3 mutation in vivo.2017

    • Author(s)
      Sayaka Yoshida, Yuya Araki, Takayasu Mori, Emi Sasaki, Yuri Kasagi, Kiyoshi Isobe, Koichiro Susa, Yuichi Inoue, Tatemitsu Rai, Shinichi Uchida,Eisei Sohara.
    • Organizer
      The 51th Annual Meeting of American Society of Nephrology.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 高カリウムはカリシニューリンを活性化しNa-Cl共輸送体(NCC)を脱リン酸化して尿中カリウム排泄を促進する.2017

    • Author(s)
      正田若菜, 野村尚弘, 安藤史顕, 森雄太郎, 森崇寧, 蘇原映誠, 頼建光, 内田信一.
    • Organizer
      第27回バゾプレシン研究会.
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 次世代シークエンサーにおける嚢胞性腎疾患遺伝子診断パネルの構築2017

    • Author(s)
      藤丸拓也, 蘇原映誠, 森崇寧, 萬代新太郎, 千賀宗子, 菊池寛昭, 安藤史顕, 森雄太郎, 野村尚弘, 内藤省太郎, 岡戸丈和, _建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 塩は近位尿細管細胞においてJAK/STAT系を介してIFNgamma関連ケモカインを抑制する2017

    • Author(s)
      新井洋平, 蘇原映誠, 高橋大栄, 浅野謙一, 田中正人, 小田真由美、洪繁、洪実, 萬代新太郎, 野村尚弘, 頼建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] ループ利尿薬はマウス骨格筋細胞分化および運動による筋肥大効果を抑制する2017

    • Author(s)
      萬代新太郎, 古川晋, 小高愛未, 畑裕, 森崇寧, 野村尚弘, 蘇原映誠, 頼建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Excitatory roles of WNK3 in layer V pyramidal neurons in the prefrontal cortex.2017

    • Author(s)
      Sinha Adya S, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S and Fukuda A.
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県・浜松市)
    • Year and Date
      2017-03-29
    • Data Source
      KAKENHI-PROJECT-26670512
  • [Presentation] CIC-Kチャネルはカリウム摂取不足時のNCC活性化と血圧上昇に重要である2017

    • Author(s)
      野村 尚弘, 正田 若菜, 高橋 大栄, 銭谷 慕子, 蘇原 映誠, 頼 建光, 内田 信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] WNK4は脂肪細胞分化の制御因子である2017

    • Author(s)
      高橋大栄, 森崇寧, 蘇原映誠. 田中都, 千賀宗子, 井上佑一, 野村尚弘, 銭谷慕子, 越智広樹, 竹田秀, 菅波孝祥, 頼建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] A High Salt Diet Suppressed CXCL9 and CXCL10 in Proximal Tubules through the IFNγ-JAK1-STAT1 Signaling Pathway2017

    • Author(s)
      Yohei Arai, Shinichi Uchida et al.
    • Organizer
      The 50th Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Association between Body Mass Index and In-hospital Mortality in Emergently Hospitalized Dialysis-Independent CKD Patients; A Nationwide Retrospective Cohort Study in Japan2017

    • Author(s)
      Hiroaki Kikuchi, Eiichiro Kanda, Fumiaki Ando, Hidehiko Sato, Kiyoshi Isobe, Takayasu Mori, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Eisei Sohara, Tomokazu Okado, Shinichi Uchida, Kiyohide Fushimi and Tatemitsu Rai
    • Organizer
      The 50th Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 保存期慢性腎臓病患者におけるサルコペニアの危険因子の検討2017

    • Author(s)
      石川聖子, 内藤省太郎, 銭谷慕子, 高橋大栄, 佐藤英彦, 飯盛聡一郎, 野村尚弘, 蘇原映誠, 神田英一郎, 岡戸丈和, 頼建光, 内田信一.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] WNK1はマクロファージにおけるLPS誘導性サイトカイン産生を抑制する2017

    • Author(s)
      新井洋平, 蘇原映誠, 浅野謙一, 田中正人, 頼建光, 内田信一
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] 次世代シークエンサーを用いた遺伝性腎疾患の解析2017

    • Author(s)
      蘇原映誠, 森崇寧, 内田信一.
    • Organizer
      第60回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Genomic background of adult polycystic kidney disease patients without a family history2017

    • Author(s)
      Takuya Fujimaru, Takayasu Mori, Akinari Sekine, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi , Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Junichi Hoshino, Yoshifumi Ubara, Shinichi Uchida, Eisei Sohara
    • Organizer
      The 50th Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Generation and analysis of KLHL3 knockout mice2016

    • Author(s)
      Emi Sasaki, Koichiro Susa, Takayasu Mori, Kiyoshi Isobe, Yuya Araki, Yuichi Inoue, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Sodium chloride suppresses interferon-gamma inducible chemokines through the JAK/STAT signaling pathway in proximal tubular epithelial cells2016

    • Author(s)
      Yohei Arai, Daiei Takahashi, Kenichi Asano, Masato Tanaka, Mayumi Oda, Shigeru B.H. Ko, Minoru S.H. Ko, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] Drug Repositioning Screening for the Discovery of Inhibitors of Keap1-Nrf2 Interaction Inhibitors by Using Fluorescent Correlation Spectroscopy2016

    • Author(s)
      Yuki Yoshizaki, Takayasu Mori, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Yuya Araki, Yutaro Mori, Fumiaki Ando, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara.
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] The Pseudohypoaldosteronism type II-causing mutant Cul3 Protein forms dimer with KLHL3 and inhibits the degradation of WNK4 dominant-negatively.2016

    • Author(s)
      Yuya Araki, Tatemitsu Rai, Eisei Sohara, Sayaka Yoshida, Takayasu Mori, Yuichi Inoue, Kiyoshi Isobe, Yutaro Mori, and Shinichi Uchida
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Excitatory roles of WNK3 in layer V pyramidal neurons in the prefrontal cortex.2016

    • Author(s)
      Sinha Adya S, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S, Fukuda A.
    • Organizer
      第63回中部日本生理学会
    • Place of Presentation
      生理学研究所(愛知県・岡崎市)
    • Year and Date
      2016-11-04
    • Data Source
      KAKENHI-PROJECT-26670512
  • [Presentation] Generation and analysis of KLHL3 knockout mice2016

    • Author(s)
      Emi Sasaki, Koichiro Susa, Takayasu Mori, Kiyoshi Isobe, Yuya Araki, Yuichi Inoue, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] Excitatory roles of WNK3 in layer V pyramidal neurons in the prefrontal cortex.2016

    • Author(s)
      Sinha Adya S, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S, Fukuda A.
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-22
    • Data Source
      KAKENHI-PROJECT-26670512
  • [Presentation] Sodium chloride suppresses interferon-gamma inducible chemokines through the JAK/STAT signaling pathway in proximal tubular epithelial cells2016

    • Author(s)
      Yohei Arai, Daiei Takahashi, Kenichi Asano, Masato Tanaka, Mayumi Oda, Shigeru B.H. Ko, Minoru S.H. Ko, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Drug Repositioning Screening for the Discovery of Inhibitors of Keap1-Nrf2 Interaction Inhibitors by Using Fluorescent Correlation Spectroscopy2016

    • Author(s)
      Yuki Yoshizaki, Takayasu Mori, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Yuya Araki, Yutaro Mori, Fumiaki Ando, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara.
    • Organizer
      Annual Meeting of the American Society of Nephrology, Kidney Week 2016
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] The KLHL proteins, the WNKs and renal Na+ transport.2015

    • Author(s)
      Uchida S
    • Organizer
      8Th FAOPS (Federation of the Asian and Oceanian Physiological Societies) Congress 2015
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2015-11-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] Dual effects of serotoninergic inputs on the local circuits regulating the corticotropin-releasing factor neurons in the paraventricular nucleus of the hypothalamus: an electrophysiological study using the CRF-VenusΔNeo mouse.2015

    • Author(s)
      Sato, T., Sugiya, T., Fuse, T., Uchida, K., Sugimoto, N., Abe, M., Yamazaki, M., Fukuda, A., Sakimura, K. and Itoi, K.
    • Organizer
      Society for Neuroscience 2015
    • Place of Presentation
      Chicago(USA)
    • Year and Date
      2015-10-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670512
  • [Presentation] The Major Contribution of WNK4 to the Pathogenesis of Pseudohypoaldosteronism Type II (PHAII) Caused by the KLHL3 Mutation R528H.2015

    • Author(s)
      Susa K, Sohara E, Takahashi D, Rai T, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] Generation of Hypertension-Associated STK39 Polymor- phism Knockin Cell Lines with the CRISPR/Cas9 System.2015

    • Author(s)
      Mandai S, Mori T, Sohara E, Rai T, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] Functional regulation of neuronal K+-Cl−cotransporter KCC2.2015

    • Author(s)
      Watanabe, M., Iwata, S., Furukawa, T., Kumada, T., Uchida, T., Hirose, S. and Fukuda, A.
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場・展示場(兵庫県・神戸市)
    • Year and Date
      2015-03-23
    • Data Source
      KAKENHI-PROJECT-26670512
  • [Presentation] Generation of Hypertension-Associated STK39 Polymor- phism Knockin Cell Lines with the CRISPR/Cas9 System.2015

    • Author(s)
      Mandai S, Mori T, Sohara E, Rai T, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Potassium-induced dephosphorylation of renal sodium-chloride cotransporter is NOT dependent on the anions.2015

    • Author(s)
      Nomura N, Shoda W, Sohara E, Rai T, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Potassium-induced dephosphorylation of renal sodium-chloride cotransporter is NOT dependent on the anions.2015

    • Author(s)
      Nomura N, Shoda W, Sohara E, Rai T, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] The Major Contribution of WNK4 to the Pathogenesis of Pseudohypoaldosteronism Type II (PHAII) Caused by the KLHL3 Mutation R528H.2015

    • Author(s)
      Susa K, Sohara E, Takahashi D, Rai T, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Generation and Analysis of Knock-In Mice Carrying Pseudohypoaldosteronism Type II-Causing Mutations in the Cullin 3 Gene.2015

    • Author(s)
      Araki Y, Rai T, Sohara E, Mori T, Inoue Y, Kikuchi E, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Generation and Analysis of Knock-In Mice Carrying Pseudohypoaldosteronism Type II-Causing Mutations in the Cullin 3 Gene.2015

    • Author(s)
      Araki Y, Rai T, Sohara E, Mori T, Inoue Y, Kikuchi E, Uchida S.
    • Organizer
      The 48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15327
  • [Presentation] The KLHL proteins, the WNKs and renal Na+ transport.2015

    • Author(s)
      Uchida S
    • Organizer
      8Th FAOPS (Federation of the Asian and Oceanian Physiological Societies) Congress 2015
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2015-11-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] WNK3 Regulates Blood Pressure Through the Regulation of Vascular OSR1/SPAK-NKCC1 Phosphorylation Cascade.2013

    • Author(s)
      Zeniya M, Sohara E, Kita S, Iwamoto T, Susa K, Mori T, Oi K, Chiga M, Takahashi D, Yang SS, Lin SH, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25670406
  • [Presentation] Chemical library screening for WNK signaling inhibitors by using fluorescent correlation spectroscopy.2013

    • Author(s)
      Mori T, Eriko K, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25670406
  • [Presentation] Impaired KLHL3-mediated ubiquitination of WNK4 activates OSR1 and SPAK kinases-NaCl cotransporter (NCC) signaling and causes hypertension.2013

    • Author(s)
      Wakabayashi M, Mori T, Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25670406
  • [Presentation] Impaired KLHL3-mediated ubiquitination of WNK4 activates OSR1 and SPAK kinases-NaCl cotransporter (NCC) signaling and causes hypertension.2013

    • Author(s)
      Wakabayashi M, Mori T, Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Clinical Significance of Urinary Thiazide-Sensitive Na-Cl Cotransporter (NCC) Measurement by Newly Development Enzyme-Linked Immunosorbent Assays.2013

    • Author(s)
      Isobe K, Mori T, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25670406
  • [Presentation] Clinical Significance of Urinary Thiazide-Sensitive Na-Cl Cotransporter (NCC) Measurement by Newly Development Enzyme-Linked Immunosorbent Assays.2013

    • Author(s)
      Isobe K, Mori T, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Chemical library screening for WNK signaling inhibitors by using fluorescent correlation spectroscopy.2013

    • Author(s)
      Mori T, Eriko K, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] KLHL2 interacts with and ubiquitinates WNK kinases.2013

    • Author(s)
      Takahashi D, Mori T, Wakabayashi M, Mori Y, Susa K, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] KLHL2 interacts with and ubiquitinates WNK kinases.2013

    • Author(s)
      Takahashi D, Mori T, Wakabayashi M, Mori Y, Susa K, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25670406
  • [Presentation] WNK3 Regulates Blood Pressure Through the Regulation of Vascular OSR1/SPAK-NKCC1 Phosphorylation Cascade.2013

    • Author(s)
      Zeniya M, Sohara E, Kita S, Iwamoto T, Susa K, Mori T, Oi K, Chiga M, Takahashi D, Yang SS, Lin SH, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 46th Annual meeting of American Society of Nephrology
    • Place of Presentation
      アトランタ, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Chemical library screening for direct SPAK inhibitors by a newly developed ELISA system2012

    • Author(s)
      Kikuchi E, Mori T, Isobe K, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Development of sandwich enzyme linked immunosorbent assay (ELISA) formeasurement of urinary total and phosphorylated Na-Cl cotransporter (NCC) protein2012

    • Author(s)
      Isobe K, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Chemical library screening for drugs to correct intracellular mislocalization of R8L mutant barttin.2012

    • Author(s)
      Uchida S
    • Organizer
      2012 International Ion Channel Conference.
    • Place of Presentation
      Shilla Hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Generation and analysis of WT-WNK4 transgenic mice revealed the physiological role of WNK42012

    • Author(s)
      Mori T, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Chemical library screening for drugs to correct intracellular mislocalization of R8L mutant barttin.2012

    • Author(s)
      Uchida S
    • Organizer
      2012 International Ion Channel Conference.
    • Place of Presentation
      the Shilla Hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates itsubiquitination2012

    • Author(s)
      Hossain Khan MZ, Sohara E, Ohta A, Chiga M, Inoue Y, Isobe K, Wakabayashi M, Naito S, Oi K, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] WNK4-OSR1/SPAK-NCC signal cascade has circadian rhythm dependent on aldosterone2012

    • Author(s)
      Susa K, Sohara E, Isobe K, Chiga M, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Dietary salt intake and angiotensin II regulates WNK-SPAK-NKCC1 phosphorylation cascade in mouse aorta2012

    • Author(s)
      Zeniya M, Sohara E, Oi K, Chiga M, SusaK, Mori T, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Chemical library screening for direct SPAK inhibitors by a newly developed ELISA system2012

    • Author(s)
      Kikuchi E, Mori T, Isobe K, Sohara E,Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of AmericanSociety of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Hereditary nephrogenic diabetes insipidus (NDI) in Japanese patients: Analysis of 73 families2012

    • Author(s)
      Sasaki S, Chiga M, Kikuchi E, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Role of WNK kinases in the blood pressure regulation.2012

    • Author(s)
      Uchida S
    • Organizer
      Taiwan Society of Nephrology 2012
    • Place of Presentation
      China Medical University
    • Invited
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] WNK4-OSR1/SPAK-NCC signal cascade has circadian rhythm dependent on aldosterone2012

    • Author(s)
      Susa K, Sohara E, Isobe K, Chiga M, RaiT, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination2012

    • Author(s)
      Hossain Khan MZ, Sohara E, Ohta A, Chiga M, Inoue Y, Isobe K, Wakabayashi M, Naito S, Oi K, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Development of sandwich enzyme linked immunosorbent assay (ELISA) for measurement of urinary total and phosphorylated Na-Clcotransporter (NCC) protein2012

    • Author(s)
      Isobe K, Sohara E, Rai T, Sasaki S,Uchida S
    • Organizer
      The 45th Annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Role of WNK kinases in the blood pressure regulation.2012

    • Author(s)
      Uchida S
    • Organizer
      Taiwan Society of Nephrology 2012
    • Place of Presentation
      China Medical University
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Generation and analysis of WT-WNK4 transgenic mice revealed the physiological role of WNK42012

    • Author(s)
      Mori T, Sohara E, Rai T, Sasaki ,Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Role of WNK kinases in the blood pressure regulation2012

    • Author(s)
      Uchida S
    • Organizer
      Taiwan Society of Nephrology 2012
    • Place of Presentation
      China Medical University, Taichung, Taiwan
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Hereditary nephrogenic diabetes insipidus (NDI) in Japanese patients: Analysis of 73 families2012

    • Author(s)
      Sasaki S, Chiga M, Kikuchi, EUchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Chemical library screening for drugs to correct intracellular mislocalization of R8L mutant barttin2012

    • Author(s)
      Uchida S
    • Organizer
      2012 International Ion Channel Conference
    • Place of Presentation
      The New world of anion and cation channels. Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Dietary salt intake and angiotensin II regulates WNK-SPAK-NKCC1 phosphorylation cascade in mouse aorta2012

    • Author(s)
      Zeniya M, Sohara E, Oi K, Chiga M, Susa K, Mori T, Rai T, Sasaki S, Uchida S
    • Organizer
      The 45th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Urinary excretion of Na-ClCotransporter in exosomes is increased by high salt diet as well as low salt diet2011

    • Author(s)
      Kahn MZH, Sohara E, Ohta A, Naito S, Chiga M, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] CFTR is highly expressed in the cyst-lining epithelial cells of the AQP11knockout mouse kidney2011

    • Author(s)
      Kobayashi K, Uchida S, Sasaki S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Chemical library screening for drugs to correct intracellular mislocalization of R8L mutant barttin2011

    • Author(s)
      Nomura N, Naito S, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Increased protein abundance of the mutant WNK4 may be a cause of the increased WNK4 kinase activity in the mouse model of pseudohypoaldosteronism type II2011

    • Author(s)
      Wakabayashi M, Naito S, Sohara E, RaiT, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] High throughput screening of drugs that inhibit WNK-OSR1/SPAK signaling cascade2011

    • Author(s)
      Mori T, Ohta A, Sohara E, Rai T, SasakiS, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Increased protein abundance of the mutant WNK4 may be a cause of the increased WNK4 kinase activity inthe mouse model of pseudohypoaldosteronism type II2011

    • Author(s)
      Wakabayashi M, Naito S, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Increased Na-Cl cotransporter phosphorylation in hyperinsulinemic db/db mice is regulated by insulin/PI3K pathway2011

    • Author(s)
      Nishida H, Sohara E, Alessi DR, NomuraN, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of AmericanSociety of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] WNK-OSR1/SPAK-SLC12A phosphorylation cascade in the WNK1 (+/-) mice2011

    • Author(s)
      Susa K, Ohta A, Sohara E, Rai T, KitaS, Iwamoto T, Alessi DR, Sasaki S, UchidaS
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] High throughput screening of drugs that inhibit WNK-OSR1/SPAK signaling cascade2011

    • Author(s)
      Mori T, Ohta A, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Development of new systems to measure total and phosphorylated Na-Cl cotransporter(NCC)protein in human urine2011

    • Author(s)
      Isobe K, Ohta A, Sohara E, Rai T, SasakiS, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Generation and analyses of AQP11 BAC transgenic mice2011

    • Author(s)
      Inoue Y, Sohara E, Kobayashi K, Rai T, Ishibashi K, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Renal phenotype of WNK3 knockout mouse2011

    • Author(s)
      Oi K, Sohara E, Rai T, Chiga M, Alessi DR, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] CFTR is highly expressed in the cyst-lining epithelial cells of the AQP11 knockout mouse kidney2011

    • Author(s)
      Kobayashi K, Uchida S, Sasaki S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Renal phenotype of WNK3 knockout mouse2011

    • Author(s)
      Oi K, Sohara E, Rai T, Chiga M, AlessiDR, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Development of new systems to measure total and phosphorylated Na-Cl cotransporter(NCC)protein in human urine2011

    • Author(s)
      Isobe K, Ohta A, Sohara E, Rai T, SasakiS, Uchida S.
    • Organizer
      The 44th Annual Meeting of AmericanSociety of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] WNK-OSR1/SPAK-SLC12A phosphorylation cascade in the WNK1 (+/-) mice2011

    • Author(s)
      Susa K, Ohta A, Sohara E, Rai T, Kita S, Iwamoto T, Alessi DR, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society ofNephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Increased Na-Cl cotransporter phosphorylation in hyperinsulinemic db/db mice is regulated by insulin/PI3K pathway2011

    • Author(s)
      Nishida H, Sohara E, Alessi DR, Nomura N, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Urinary excretion of Na-Cl Cotransporter in exosomes is increased by high salt diet as well as low salt diet2011

    • Author(s)
      Kahn MZH, Sohara E, Ohta A, Naito S, Chiga M, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Acute insulin stimulation inducesphosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney2011

    • Author(s)
      Sohara E, Rai T, Yang SS, Ohta A, Chiga M, Nomura N, Lin SH, Vandewalle A, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] A new signal cascade in kidney regulating blood pressure and ion homeostasis2011

    • Author(s)
      Uchida S
    • Organizer
      The 23^<rd> Annual Meeting of the Korean Society for Molecular and Cellular Biology
    • Place of Presentation
      COEX, Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Chemical library screening for drugs to correct intracellular mislocalization of R8L mutant barttin2011

    • Author(s)
      Nomura N, Naito S, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney2011

    • Author(s)
      Sohara E, Rai T, Yang SS, Ohta A, Chiga M, Nomura N, Lin SH, Vandewalle A, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Generation and analyses of AQP11 BAC transgenic mice2011

    • Author(s)
      Inoue Y, Sohara E, Kobayashi K, Rai T,Ishibashi K, Sasaki S, Uchida S
    • Organizer
      The 44th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] よくわかるシリーズ(遺伝子改変動物を用いた腎臓病研究).2010

    • Author(s)
      内田信
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Treatment of Bartter syndrome type IV caused by R8L barttin mutation2010

    • Author(s)
      Nomura N, Masato T, Ohta E, Ohta A, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 43nd Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Denver (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] 腎臓でのNaCl およびK 出納調節におけるWNK キナーゼの役割2010

    • Author(s)
      内田信一
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] 腎臓でのNaClおよびK出納調節におけるWNKキナーゼの役割.2010

    • Author(s)
      内田信
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Molecular pathogenesis of Bartter syndrome caused by R8L barttin mutation.2009

    • Author(s)
      Uchida S, Nomura N, Sugawara N, Morimoto T, Kondo Y, Naito S, Yui N, Oi K, Talat G, KMZ Hossain, Wakabayashi M, Nishida H, Ohta E, Ohta A, Sohara E, Rai T, Sasaki S.
    • Organizer
      40th NIPS International Symposium & Physiology of anion transport and cell volume regulation (PAT-CVR 2009)
    • Place of Presentation
      Okazaki
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Molecular pathogenesis of Bartter syndrome caused by R8L barttin mutation2009

    • Author(s)
      Uchida S, Nomura N, Sugawara N, Morimoto T, Kondo Y, Naito S, Yui N, Oi K, Talat G , KMZ Hossain, Wakabayashi M, Nishida H, Ohta E, Ohta A, Sohara E, Rai T, Sasaki S
    • Organizer
      The 40th NIPS International Symposium & Physiology of anion transport and cell volume regulation (PAT-CVR 2009)
    • Place of Presentation
      Okazaki
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] 輸送体研究の新展開:新しい解析技術による創薬標的の実体と病態の解明. 疾患起因性変異ノックインマウスの解析による腎臓の水・電解質輸送機構の解明2009

    • Author(s)
      内田信一
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Generation and analysis of the BsndR8L/R8L knockin mice2009

    • Author(s)
      Nomura N, Masato T, Morimoto T, Kondo Y, Ohta E, Ohta A, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 42nd Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] WNKキナーゼによる腎臓での新たな塩分出納調節機構2009

    • Author(s)
      内田信一
    • Organizer
      第44回日本小児腎臓病学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] トランスポーター研究のパラダイムシフト:ヒトシステムの理解を目指して.ヒト遺伝性高血圧症原因遺伝子の機能解析から明らかになった腎臓での新たなNaCl出納調節系2009

    • Author(s)
      内田信一
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] WNK キナーゼの腎尿細管における役割2009

    • Author(s)
      内田信一
    • Organizer
      第31回腎臓セミナー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] シンポジウム トランスポーター研究のパラダイムシフト:ヒトシステムの理解を目指して.ヒト遺伝性高血圧症原因遺伝子の機能解析から明らかになった腎臓での新たなNaCl 出納調節系2009

    • Author(s)
      内田信一
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Calcium, Magnesium, and Calcimimetics Decrease Paracellular Na+Permeability in Mouse Thin Ascending Limb of Henle's Loop2009

    • Author(s)
      Morimoto T, Sugawara N, Uchida S, Farajov EI, Kamada F, Kumagai N, Aslanova UF, Sasaki S, Tsuchiya S, Kondo Y
    • Organizer
      第42回アメリカ腎臓学会
    • Place of Presentation
      San Diego
    • Year and Date
      2009-10-11
    • Data Source
      KAKENHI-PROJECT-19390279
  • [Presentation] Effect of angiotensin II on WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney2009

    • Author(s)
      Talati G, Ohta A, Rai T, Sohara E, Naito S, Vandewalle A, Sasaki S, Uchida S
    • Organizer
      The 42st Annual Meetingof American Society of Nephrology
    • Place of Presentation
      SanDiego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] トランスポーター研究のパラダイムシフト:ヒトシステムの理解を目指して.ヒト遺伝性高血圧症原因遺伝子の機能解析から明らかになった腎臓での新たなNaCl出納調節系2009

    • Author(s)
      内田信一
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] トランスポーター研究のパラダイムシフト:ヒトシステムの理解を目指して. ヒト遺伝性高血圧症原因遺伝子の機能解析から明らかになった腎臓での新たなNaCl出納調節系2009

    • Author(s)
      内田信一
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Epithelial transport: bridges between molecules and function. WNK kinases and cation-chloride cotransporters, novel transportsomes regulating blood pressure2009

    • Author(s)
      Uchida S. Symposium.
    • Organizer
      The 36th International Congress of Physiological Sciences (IUPS2009)
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] WNKキナーゼによる腎臓での新たな塩分出納調節機構2009

    • Author(s)
      内田信一
    • Organizer
      第44回日本小児腎臓病学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] WNKキナーゼによる腎臓での新たな塩分出納調節機構2009

    • Author(s)
      内田信一
    • Organizer
      第44回日本小児腎臓病学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Targeted disruption of pancreatic-specific water-Channel, aquaporin-12, results in increased susceptibility to drug-induced acute pancreatitis2009

    • Author(s)
      Ohta E, Itoh T, Nemoto T, Kumagai J, Ko S, Ishibashi K, Kawashima M, Uchida K, Ohta A, Rai T, Uchida S, Sasaki S.
    • Organizer
      World Congress of Nephrology 2009
    • Place of Presentation
      Milan
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] Investigation of the localization of mouse WNK3 in kidney2009

    • Author(s)
      Oi K, Sohara E, Ohta A, Ohta E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 42nd Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Regulation of WNK1 activation by extracellular ionic conditions2009

    • Author(s)
      Naito S, Ohta A, Ohta E, Sohara E, Rai T, Sasaki S, Uchida S
    • Organizer
      The 42nd Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego(USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Novel insulin-WNK4-NCC phosphorylation cascade is involved in pathogenesis of PHA II caused by WNK4R1185C mutation2009

    • Author(s)
      Sohara E, Rai T, Ohta A, Ohta E, Sasaki S and Uchida S
    • Organizer
      The 42nd Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] 教育講演 WNK キナーゼによる腎臓での新たな塩分出納調節機構2009

    • Author(s)
      内田信一
    • Organizer
      第44回日本小児腎臓病学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Increased phosphorylation of Na-Cl cotransporter (NCC) in the mouse model of pseudohypoaldosteronism type II was dependent on both OSR1 and SPAK kinase activity2009

    • Author(s)
      Chiga M, Ohta A, Rai T, Sohara E, Ohta E, Rafiqi FH, Alessi DR, Sasaki S, Uchida S
    • Organizer
      The 42nd Annual Meeting ofAmerican Society of Nephrology
    • Place of Presentation
      San Diego(USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] シンポジウム 輸送体研究の新展開:新しい解析技術による創薬標的の実体と病態の解明.疾患起因性変異ノックインマウスの解析による腎臓の水・電解質輸送機構の解明2009

    • Author(s)
      内田信一
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] The primary cilia of the AQP11 knockout mouse kidney2008

    • Author(s)
      Kobayashi K, Uchida S, Sasaki S
    • Organizer
      The 41st Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] "Transport regulation by phosphorylation" Phosphorylation- dependent regulation of NCC by WNKs.2008

    • Author(s)
      Uchida S
    • Organizer
      The 41^<st> Annual meeting of AmericanSociety of Nephrology
    • Place of Presentation
      フィラデルフィア
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] Basic and Clinical Science Symposium, "Transport regulation by phosphorylation"Phosphorylation-dependent regulation of NCC by WNKs2008

    • Author(s)
      Uchida S
    • Organizer
      The 41st Annual meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Analysis of pancreatic exocrine function ofaquaporin-12 knockout mice2008

    • Author(s)
      Ohta E, Itoh T, Nemoto T, Kumagai J, Ko SBH, Ishibashi K, Ohno M, Uchida K, Ohta A, Rai T, Uchida S, Sasaki S
    • Organizer
      The 41st Annual meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Basic and Clinical Science Symposium, "Transport regulation by phosphorylation" Phosphorylation-dependent regulation of NCC by WNKs.2008

    • Author(s)
      Uchida S.
    • Organizer
      The 41st Annual meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] "Transport regulation by phosphorylation" Phosphorylation- dependent regulation of NCC by WNKs.2008

    • Author(s)
      Uchida S
    • Organizer
      The 41^<st> Annual meeting of AmericanSociety of Nephrology
    • Place of Presentation
      フィラデルフィア
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] Basic and Clinical Science Symposium, "Transport regulation by phosphorylation" Phosphorylation-dependent regulation of NCC by WNKs.2008

    • Author(s)
      Uchida S.
    • Organizer
      The 41st Annual meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Targeted disruption of the Wnk4 gene reduced the phospholylation of OSR1/SPAK and Na-Cl cotransporter in mice2008

    • Author(s)
      Ohta A, Chiga M, Tajima M, Yang SS, Naito S, Rai T, Uchida S, Sasaki S
    • Organizer
      The 41st Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia (USA)
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] "Transport regulation by phosphorylation" Phosphorylation- dependent regulation of NCC by WNKs.2008

    • Author(s)
      Uchida S
    • Organizer
      The 41^<st> Annual meeting of AmericanSociety of Nephrology
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2008-11-09
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Generation and analysis of Wnk4D561A/+ knock-in mice2007

    • Author(s)
      Yang S, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin S, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.
    • Organizer
      ISN - Nature Genetics Forefronts Symposium on Nephrogenetics : from Development to Physiology
    • Place of Presentation
      Danvers, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Presentation] シンポジウム 遺伝子改変マウスを用いた水・電解質異常症の分子病態の解祈.2007

    • Author(s)
      内田 信一
    • Organizer
      第84回日本生理学会大会
    • Place of Presentation
      大阪国際交流センター
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Presentation] シンポジウム遺伝子改変マウスを用いた水・電解質異常症の分子病態の解析.2007

    • Author(s)
      内田 信一
    • Organizer
      第84回日本生理学会大会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Generation and analysis of Wnk4D561A/+ knock-in mice.2007

    • Author(s)
      Yang S, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin S, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.
    • Organizer
      ISN- Nature Genetics Forefronts Symposium on Nephrogenetics: from Development to Physiology
    • Place of Presentation
      Danvers, USA
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] シンポジウム遺伝性高血圧尿細管機能異常症に学ぶ腎臓の電解質輸送の最新の知見.2007

    • Author(s)
      内田 信一
    • Organizer
      第37回日本腎臓学会東部学術大会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] シンポジウム 遺伝性高血圧尿細管機能異常症に学ぶ腎臟の電解質輸送の最新の知見2007

    • Author(s)
      内田 信一
    • Organizer
      第37回日本腎臟学会東部学術大会
    • Place of Presentation
      埼玉県大宮市
    • Year and Date
      2007-10-06
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] シンポジウム 遺伝子改変マウスを用いた水・電解質異常症の分子病態の解析2007

    • Author(s)
      内田 信一
    • Organizer
      第84回日本生理学会大会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2007-03-21
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] シンポジウム 遺伝性高血圧尿細管機能異常症に学ぶ腎臓の電解質輸送の最新の知見.2007

    • Author(s)
      内田 信一
    • Organizer
      第37回日本腎臓学会東部学術大会
    • Place of Presentation
      大宮
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Presentation] シンポジウム遺伝性高血圧尿細管機能異常症に学ぶ腎臓の電解質輸送の最新の知見2007

    • Author(s)
      内田 信一
    • Organizer
      第37回日本腎臓学会東部学術大会
    • Place of Presentation
      大宮
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390246
  • [Presentation] Identification of protein complex isolated with a mutant AQP2 that causes autosominal dominant nephrogenic diabetes insipidus.2006

    • Author(s)
      Araki Y, Sohara E, Rai T, Sasaki S, Uchida S.
    • Organizer
      The 39th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice2005

    • Author(s)
      Sohara E, Rai T, Verkman A. S., Sasaki S, Uchida S.
    • Organizer
      38^<th> Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Philadelphia
    • Year and Date
      2005-11-11
    • Data Source
      KAKENHI-PROJECT-17GS0312
  • [Presentation] Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.2005

    • Author(s)
      Sohara E, Rai T, Verkman AS, Sasaki S, Uchida S.
    • Organizer
      4th International Conference on Aquaporins
    • Place of Presentation
      Brussels
    • Data Source
      KAKENHI-PROJECT-17081009
  • [Presentation] Epithelial transport: bridges between molecules and function

    • Author(s)
      Uchida S
    • Organizer
      WNK kinases and cation-chloride cotransporters, novel transportsomes regulating blood pressure
    • Data Source
      KAKENHI-PROJECT-20249047
  • [Presentation] A new signal cascade in kidney regulating blood pressure and ion homeostasis.

    • Author(s)
      Uchida S
    • Organizer
      The 23rd Annual Meeting of the Korean Society for Molecular and Cellular Biology(招待講演)
    • Place of Presentation
      COEX, Seoul, Korea.
    • Data Source
      KAKENHI-PROJECT-23659439
  • [Presentation] Impaired KLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension.

    • Author(s)
      Uchida S.
    • Organizer
      The 47th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      フィラデルフィア、米国
    • Year and Date
      2014-11-13 – 2014-11-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221306
  • [Presentation] Impaired KLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension.

    • Author(s)
      Uchida S.
    • Organizer
      The 47th Annual Meeting of American Society of Nephrology
    • Place of Presentation
      フィラデルフィア、米国
    • Year and Date
      2014-11-13 – 2014-11-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670406
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    # of Collaborated Projects: 7 results
    # of Collaborated Products: 85 results
  • 2.  KONDO Yoshiaki (00221250)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 3.  FUJIWARA Ikuma (10271909)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  OHURA Toshihiro (10176828)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  MUNAKATA Mitsutoshi (30312573)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  FUSHIMI Kiyohide (50270913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SAKAMOTO Hisato (80187046)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  INASE Naohiko (60262185)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  IINUMA Kazuie (80004927)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  河崎 雅暢
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  ISHIBASHI Kenichi (80223022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  KOBAYASHI Katsuki (40415451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NODA Yumi (30372436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  MORIMOTO TETSUJI (10344657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 18.  AKITA Tenpei (00522202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 19.  WATANABE Miho (10399321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  MUTOH Hiroki (60443040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 21.  HATA Kenichiro (60360335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  古川 哲史 (80251552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  丸茂 文昭 (00050443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SOHARA Eisei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 40 results
  • 25.  ASANO Kenichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 26.  AIDA Tomomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  ISHIDA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  MORI shuichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  KO Shigeru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  FUJII Makoto
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  OHARA Osamu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  有田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  頼 建光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 28 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 10 results
  • 35.  磯部 清志
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    # of Collaborated Products: 6 results
  • 36.  南嶋 洋司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  銭谷 慕子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 38.  高橋 大栄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 39.  若林 麻衣
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    # of Collaborated Products: 2 results
  • 40.  岩本 隆宏
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    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 42.  大井 克征
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 2 results
  • 44.  橋本 博子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  森 崇寧
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  安藤 史顕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 47.  油井 直史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 48.  井上 佑一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 49.  藤井 晋也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 50.  西田 秀範
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 51.  森 満
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  竹田 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  高橋 悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  佐々木 泰史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 55.  高橋 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  井上 純一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  須佐 紘一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 58.  畑 裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 59.  古市 泰郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 60.  太田 哲人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 61.  小田 真由美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 62.  田中 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 63.  影近 弘之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 64.  越智 広樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 65.  菅波 孝祥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 66.  田中 都
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 67.  後藤 雄輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 68.  田頭 秀章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 69.  神谷 和作
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 70.  池田 勝久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 71.  野々山 恵章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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