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Moribe Kunikazu  森部 久仁一

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MORIBE Kunikazu  森部 久仁一

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Researcher Number 50266350
Other IDs
Affiliation (Current) 2023: 千葉大学, 大学院薬学研究院, 教授
Affiliation (based on the past Project Information) *help 2015 – 2022: 千葉大学, 大学院薬学研究院, 教授
2014 – 2015: 千葉大学, 薬学研究科(研究院), 教授
2011 – 2013: 千葉大学, 薬学研究科(研究院), 准教授
2007 – 2012: 千葉大学, 大学院・薬学研究院, 准教授
2007: Chiba University, 大学院・葉学研究院, 准教授
2006: 千葉大学, 大学院薬学研究院, 助教授
2004 – 2005: 千葉大学, 大学院・薬学研究院, 助教授
Review Section/Research Field
Principal Investigator
Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Except Principal Investigator
Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Biomedical engineering/Biological material science / Medical pharmacy
Keywords
Principal Investigator
NMR / ナノ微粒子 / テラヘルツ / 固体分散体 / 相互作用 / ポリマー / AFM / 混合粉砕 / ポリビニルピロリドン / ドデシル硫酸ナトリウム … More / ヒドロキシプロピルメチルセルロース / 固体NMR / プロブコール / 計算科学 / 複合体 / cocrystal / 非破壊 / 結晶工学 / 溶液構造 / 原子間力顕微鏡 / 溶液 / 分子状態 / 可溶化 / 構溶液造 / 過飽和 / 固体分散体過飽和 / 原子間力顕微鏡(AFM) / ナノ粒子 / 力学特性 / 構造評価 / 透過型電子顕微鏡(TEM) / 原子間力顕微鏡(AFM / 液中測定 / ナノ / 溶解性改善 / SAXS / 運動性 / 難水溶性薬物 / 溶解 … More
Except Principal Investigator
難水溶性薬物 / 溶解性改善 / 非晶質 / 分子間相互作用 / NMR / Cryo-TEM / 安定性 / 有機ナノチューブ / 放出制御 / 固体NMR / 結晶多形 / 固液界面 / 運動性 / 湿式粉砕 / 脂質ナノ粒子 / 非晶質ナノ粒子 / suspended-state NMR / 人工血管 / 徐放剤 / 内膜肥厚 / 再生医療 / 経口製剤 / 固体分散体 / 刺激応答性 / 分子製剤学 / シクロデキストリン / 分子状態 / 薬物溶解性 / 超分子複合体 / 溶出速度 / ナノチューブ / ポリシュードロタキサン / 薬物封入 / 薬物ナノ懸濁液 / Suspended state NMR / 薬物ナノ粒子 / 多形 / indomethacin / piroxicam / poloxamer / ナノ懸濁液 / suspended state NMR / 表面構造 / 分散安定性 / Indometacin / Poloxamer / ナノ粒子 / バイセル / DDS / 脂質構造体 / 構造解析 / 薬学 / 非晶質固体分散体 / 界面活性剤 / 安定化 / STEM-EDX / 表面エネルギー / 溶解性 / cryo-TEM / 薬物濃縮相 / 液-液相分離 / 過飽和 / 界面 Less
  • Research Projects

    (14 results)
  • Research Products

    (162 results)
  • Co-Researchers

    (17 People)
  •  Development of drug-rich phase-coexisting lipid nanoparticle formulations based on elucidation of molecular mechanism of liquid-liquid phase separation phenomenon of drugs

    • Principal Investigator
      植田 圭祐
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Chiba University
  •  Structural evaluation of solid-liquid interface of drug nanoamorphous by suspended-state NMR

    • Principal Investigator
      東 顕二郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Chiba University
  •  Drug dissolution mechanism based on evaluation of polymer structure, mobility, and intermolecular interactionPrincipal Investigator

    • Principal Investigator
      森部 久仁一
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Chiba University
  •  Design of drug amorphous nanosuspension to achieve a pharmaceutical formulation of poorly water-soluble drug

    • Principal Investigator
      Higashi Kenjirou
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Chiba University
  •  Pharmaceutical application of novel lipid nanocarrier bicelle

    • Principal Investigator
      Itai Shigeru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      University of Shizuoka
  •  Refined structural analysis and mechanical property of drug nano-formulation by AFM in aqueous meidaPrincipal Investigator

    • Principal Investigator
      MORIBE KUNIKAZU
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  Evaluation of molecular state of drug nanosuspensions by suspended-state NMR spectroscopy

    • Principal Investigator
      Higashi Kenjirou
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  Design of supramolecular complexes to form asymmetry nanotube structure and the application for controlled release carrier

    • Principal Investigator
      Yamamoto Keiji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  Structure of supersaturated solution of poorly water-soluble drug indexed by mobility and diffusibility and the correlation with membrane permeabilityPrincipal Investigator

    • Principal Investigator
      MORIBE Kunikazu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  Encapsulation of a poorly water-soluble drug with large molecular size into organic nanotube

    • Principal Investigator
      YAMAMOTO Keiji
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  Structural evaluation of drug solution by ATR terahertz, NMR, DSC, and viscometryPrincipal Investigator

    • Principal Investigator
      MORIBE Kunikazu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  Healing of Dacron graft : role of bFGF and extracellular matrix using agarose hydrogel particles as a controlled release reservoir

    • Principal Investigator
      ISHIDA Atsushi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Jikei University School of Medicine
      Chiba University
  •  Evaluation of molecular states of drug in solid dispersion by terahertz spectroscopy and computational calculationPrincipal Investigator

    • Principal Investigator
      MORIBE Kunikazu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
  •  混合粉砕法による自己乳化型医薬品封入ナノ微粒子の開発Principal Investigator

    • Principal Investigator
      森部 久仁一
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 Other

All Journal Article Presentation Book

  • [Book] ナノ・マイクロ微粒子の分散評価技術 核磁気共鳴(分担)2020

    • Author(s)
      東 顕二郎、植田 圭祐、森部 久仁一 (分担)
    • Total Pages
      227
    • Publisher
      シーエムシー出版
    • ISBN
      9784781314907
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Book] 粉体の表面処理・複合化技術集大成2018

    • Author(s)
      東顕二郎、植田圭祐、森部久仁一 分担執筆、内藤 牧男 監修
    • Total Pages
      752
    • Publisher
      テクノシステム
    • ISBN
      9784924728813
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Book] 難水溶性薬物の経口製剤化技術最前線2016

    • Author(s)
      東 顕二郎, 森部 久仁一
    • Total Pages
      14
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Book] ナノ結晶化技術の基礎と医薬品開発の現状, 難水溶性薬物の経口製剤化技術最前線2016

    • Author(s)
      東顕二郎, 森部久仁一(分担)
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Book] 医薬ジャーナル:各種ポリマーによる難水溶性薬物の溶解性改善機構の解明と製剤化への応用 (特集 実用可能な新しい製剤技術の進歩と将来展望)2014

    • Author(s)
      植田 圭祐, 東 顕二郎, 森部 久仁一
    • Total Pages
      256
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Journal Article] Transition from Amorphous Cyclosporin A Nanoparticles to Size-Reduced Stable Nanocrystals in a Poloxamer 407 Solution2022

    • Author(s)
      Chen Ziqiao、Higashi Kenjirou、Ueda Keisuke、Moribe Kunikazu
    • Journal Title

      Molecular Pharmaceutics

      Volume: 19 Pages: 188-199

    • DOI

      10.1021/acs.molpharmaceut.1c00721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16334, KAKENHI-PROJECT-21K06509
  • [Journal Article] Nanostructure and molecular-level characterization of aminoalkyl methacrylate copolymer and the impact on drug solubilization ability.2021

    • Author(s)
      Okamoto Yuta、Higashi Kenjirou、Morita Takeshi、Ueda Keisuke、Mukaide Sayaka、Takeda Junpei、Karashima Masatoshi、Ikeda Yukihiro、Moribe Kunikazu
    • Journal Title

      Mol. Pharm.

      Volume: 18 Pages: 4111-4121

    • DOI

      10.1021/acs.molpharmaceut.1c00526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16334, KAKENHI-PROJECT-20K06985
  • [Journal Article] Revealing the mechanism of morphological variation of amorphous drug nanoparticles formed by aqueous dispersion of ternary solid dispersion2021

    • Author(s)
      Zhao Zhijing、Higashi Kenjirou、Ueda Keisuke、Moribe Kunikazu
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 607 Pages: 120984-120984

    • DOI

      10.1016/j.ijpharm.2021.120984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16334, KAKENHI-PROJECT-21K06509
  • [Journal Article] Clarification of the Dissolution Mechanism of an Indomethacin/Saccharin/Polyvinylpyrrolidone Ternary Solid Dispersion by NMR Spectroscopy2020

    • Author(s)
      Kosaka Mami、Higashi Kenjirou、Nishimura Misaki、Ueda Keisuke、Moribe Kunikazu
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 109 Pages: 3617-3624

    • DOI

      10.1016/j.xphs.2020.09.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K06985, KAKENHI-PROJECT-19K16334
  • [Journal Article] Cryo-TEM and AFM observation of the time-dependent evolution of amorphous probucol nanoparticles formed by the aqueous dispersion of ternary solid dispersions2019

    • Author(s)
      Zhao Z, Katai H, Higashi K, Ueda K, Kawakami K, Moribe K
    • Journal Title

      Molecular Pharmaceutics

      Volume: 印刷中 Pages: 2184-2198

    • DOI

      10.1021/acs.molpharmaceut.9b00158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08190, KAKENHI-PROJECT-18K06592, KAKENHI-PROJECT-19K16334
  • [Journal Article] Nano-scale and molecular-level understanding of wet-milled indomethacin/poloxamer 407 nanosuspension with TEM, suspended-state NMR, and Raman measurements2018

    • Author(s)
      Kuroiwa Yosuke、Higashi Kenjirou、Ueda Keisuke、Yamamoto Keiji、Moribe Kunikazu
    • Journal Title

      International journal of pharmaceutics

      Volume: 537 Pages: 30-39

    • DOI

      10.1016/j.ijpharm.2017.12.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Determination of Nonspherical Morphology of Doxorubicin-Loaded Liposomes by Atomic Force Microscopy.2018

    • Author(s)
      Takahashi N, Higashi K, Ueda K, Yamamoto K, Moribe K.
    • Journal Title

      J Pharm Sci.

      Volume: 107 Pages: 717-726

    • DOI

      10.1016/j.xphs.2017.10.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Journal Article] Morphological and physicochemical evaluation of two distinct glibenclamide/hypromellose amorphous nanoparticles prepared by the antisolvent method.2018

    • Author(s)
      Yonashiro, H., Higashi, K., Morikawa, C., Ueda, K., Itoh, T., Ito, M., Masu, H., Noguchi, S., Moribe, K.
    • Journal Title

      Molecular Pharamceutics

      Volume: 15(4) Pages: 1587-1597

    • DOI

      10.1021/acs.molpharmaceut.7b01122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Journal Article] Combination of Roll Grinding and High-Pressure Homogenization Can Prepare Stable Bicelles for Drug Delivery2018

    • Author(s)
      Matsuo S, Higashi K, Moribe K, Kimura SI, Itai S, Kondo H, Iwao Y
    • Journal Title

      Nanomaterials (Basel)

      Volume: 8 Pages: 998-998

    • DOI

      10.3390/nano8120998

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08455
  • [Journal Article] A solid-phase mediated methodology to incorporate drug into intermolecular spaces of CD columns in the PEG/CD-polypseudorotaxanes by cogrinding and subsequent heating2017

    • Author(s)
      Ogawa, M., Higashi, K., Namiki, S., Liu, N. Ueda, K., Limwikrant, W., Yamamoto, K., Moribe, K.
    • Journal Title

      Cryst. Growth Des.

      Volume: 17(3) Pages: 1055-1068

    • DOI

      10.1021/acs.cgd.6b01410

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Effect of guest drug character encapsulated in the cavity and intermolecular spaces of γ-cyclodextrins on the dissolution property of ternary γ-cyclodextrin complex2017

    • Author(s)
      Liu Nan、Higashi Kenjirou、Ueda Keisuke、Moribe Kunikazu
    • Journal Title

      International journal of pharmaceutics

      Volume: 531 Pages: 543-549

    • DOI

      10.1016/j.ijpharm.2017.04.049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Structural elucidation of a novel transglycosylated compound α-glucosyl rhoifolin and of α-glucosyl rutin by NMR spectroscopy2017

    • Author(s)
      Aoki Chisa、Takeuchi Yoshihiro、Higashi Kenjirou、Okamoto Yuta、Nakanishi Akihito、Tandia Mahamadou、Uzawa Jun、Ueda Keisuke、Moribe Kunikazu
    • Journal Title

      Carbohydrate Research

      Volume: 443-444 Pages: 37-41

    • DOI

      10.1016/j.carres.2017.03.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Composition-dependent structural changes and antitumor activity of ASC-DP/DSPE-PEG nanoparticles.2016

    • Author(s)
      Higashi, K., Mibu, F., Saito, K., Limwikrant, W., Yamamoto, K., Moribe, K.
    • Journal Title

      Eur. J. Pharm. Sci.

      Volume: 99 Pages: 24-31

    • DOI

      10.1016/j.ejps.2016.11.029

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Journal Article] Molecular-level understanding of the encapsulation and dissolution of poorly water-soluble ibuprofen by functionalized organic nanotubes using solid-state NMR spectroscopy.2016

    • Author(s)
      Liu, N., Higashi, K., Kikuchi, J., Ando, S., Kameta, N., Ding, W., Masuda, M., Shimizu, T., Ueda, K., Yamamoto, K., Moribe, K.
    • Journal Title

      J. Phys. Chem B

      Volume: 120(19) Pages: 4496-4507

    • DOI

      10.1021/acs.jpcb.6b00939

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Crystallization of probucol in nanoparticles revealed by AFM analysis in aqueous solution2015

    • Author(s)
      Egami, K., Higashi, K., Yamamoto, K., Moribe, K.
    • Journal Title

      Molecular Pharmaceutics

      Volume: 12 (8) Pages: 2972-2980

    • DOI

      10.1021/acs.molpharmaceut.5b00236

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Direct evaluation of molecular states of piroxicam/poloxamer nanosuspension by suspended-state NMR and Raman spectroscopies2015

    • Author(s)
      Hasegawa, Y., Higashi, K., Yamamoto, K., Moribe, K.
    • Journal Title

      Molecular Pharmaceutics

      Volume: 12 (5) Pages: 1564-1572

    • DOI

      10.1021/mp500872g

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Journal Article] Inhibition mechanism of hydroxypropyl methylcellulose acetate succinate on drug crystallization in gastrointestinal fluid and drug permeability from a supersaturated solution2014

    • Author(s)
      Ueda, K., Higashi, K., Kataoka, M., Yamashita, S., Yamamoto, K., Moribe, K.
    • Journal Title

      Eur. J. Pharm. Sci.

      Volume: 62 Pages: 290-300

    • DOI

      10.1016/j.ejps.2014.06.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J03968, KAKENHI-PROJECT-24590045
  • [Journal Article] Encapsulation of poorly water-soluble drugs into organic nanotubes for improving drug dissolution2014

    • Author(s)
      Moribe, K., Makishima, T., Higashi, K, Liu, N., Limwikrant, W., Ding, W., Masuda, M., Shimizu, T., Yamamoto, K.
    • Journal Title

      Int. J. Pharm.

      Volume: 469 (1) Pages: 190-196

    • DOI

      10.1016/j.ijpharm.2014.04.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Journal Article] The effect of HPMCAS functional groups on drug crystallization from the supersaturated state and dissolution improvement2014

    • Author(s)
      Ueda, K., Higashi, K., Yamamoto, K., Moribe, K
    • Journal Title

      Int. J. Pharm.

      Volume: 464 (1-2) Pages: 205-213

    • DOI

      10.1016/j.ijpharm.2014.01.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J03968, KAKENHI-PROJECT-24590045
  • [Journal Article] Application of intermolecular spaces between polyethylene glycol/γ-cyclodextrin-polypseudorotaxanes as a host for various guest drugs2014

    • Author(s)
      Higashi, K., Waraya, H., Lin, L. K., Namiki, S., Ogawa, M., Limwikrant, W., Yamamoto, K., Moribe, K.
    • Journal Title

      Cryst. Growth Des.

      Volume: 14 (6) Pages: 2773-2781

    • DOI

      10.1021/cg401934v

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Journal Article] Structural evaluation of probucol nano particles in water by atomic force microscopy2012

    • Author(s)
      K. Moribe, W. Limwikrant, K. Higashi, K. Yamamoto
    • Journal Title

      Int J Pharm

      Volume: 427 Pages: 365-371

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Yellow coloration phenomena of incorporated indomethacin into folded sheet mesoporous materials2012

    • Author(s)
      S. Tanabe, K. Higashi, M. Umino, W. Limwikrant, K. Yamamoto, K. Moribe
    • Journal Title

      Int. J. Pharm

      Volume: 429 Pages: 38-45

    • Data Source
      KAKENHI-PROJECT-23659017
  • [Journal Article] Structural evaluation of probucol nanoparticles in water by atomic force microscopy2012

    • Author(s)
      K.Moribe, W.Limwikrant, K.Higashi, K.Yamamoto
    • Journal Title

      Int J Pharm

      Volume: 427 Pages: 365-371

    • DOI

      10.1016/j.ijpharm.2012.02.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Molecular-level characterization ofprobucol nanocrystal in water by insitu solid-state NMR spectroscopy.2012

    • Author(s)
      J. Zhang, K. Higashi, W. Limwikrant, K. Moribe, K. Yamamoto
    • Journal Title

      Int. J. Pharm

      Volume: 423 Pages: 571-576

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Stabilization of a Supersaturated Solution of Mefenamic Acid from a Solid Dispersion with EUDRAGIT(R)EPO2012

    • Author(s)
      Kojima, K. Higashi, T. Suzuki, K. Tomono, K. Moribe, K. Yamamoto
    • Journal Title

      Pharm Res

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Transglycosylated rutin-specific non-surface-active nanostructure affects absorption enhancement of flurbiprofen.2012

    • Author(s)
      Yuichi Tozuka
    • Journal Title

      Eur J Pharm Biopharm.

      Volume: 82 Pages: 120-126

    • DOI

      10.1016/j.ejpb.2012.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790041, KAKENHI-PROJECT-24590045
  • [Journal Article] Stabilization of a supersaturated solution of mefenamic acid from a solid dispersion with EUDRAGIT^[○!R] EPO2012

    • Author(s)
      T.Kojima, K.Higashi, T.Suzuki, K.Tomono, K.Moribe, K. Yamamoto
    • Journal Title

      Pharmaceutical Research

      Volume: (印刷中) Pages: 2777-2791

    • DOI

      10.1007/s11095-011-0655-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038, KAKENHI-PROJECT-22590149, KAKENHI-PROJECT-24790041
  • [Journal Article] Molecular-level characterization of probucol nanocrystal in water by in situ solid-state NMR spectroscopy2012

    • Author(s)
      J.Zhang, K.Higashi, W. Limwikrant, K.Moribe, K.Yamamoto
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 423 Pages: 571-576

    • DOI

      10.1016/j.ijpharm.2011.11.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038, KAKENHI-PROJECT-21790032, KAKENHI-PROJECT-24790041
  • [Journal Article] Yellow coloration phenomena of incorporated indomethacin into folded sheet mesoporous materials.2012

    • Author(s)
      S.Tanabe
    • Journal Title

      Int. J. Pharm.

      Volume: (印刷中) Pages: 38-45

    • DOI

      10.1016/j.ijpharm.2012.03.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790032, KAKENHI-PROJECT-23659017
  • [Journal Article] Mechanistic differences in permeation behavior of supersaturated and solubilized solutions of carbamazepine revealed by nuclear magnetic resonance measurements2012

    • Author(s)
      Ueda K, Higashi K, Limwikrant W, Sekine S, Horie T, Yamamoto K, Moribe K.
    • Journal Title

      Mol Pharm

      Volume: 9 Pages: 3023-3033

    • DOI

      10.1021/mp300083e

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249003, KAKENHI-PROJECT-23659073, KAKENHI-PROJECT-23790172, KAKENHI-PROJECT-24590045
  • [Journal Article] Structural evaluation of crystalline ternary γ-cyclodextrin complex.2011

    • Author(s)
      K.Higashi, S.Ideura, H.Waraya, K.Moribe, K.Yamamoto
    • Journal Title

      J.Pharm.Sci.

      Volume: 100 Pages: 325-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Guest molecular size-dependent inclusion complexation of parabens with cholic acid by cogrinding2011

    • Author(s)
      K.Moribe, M.Masaki, R.Kinoshita, J.Zhang, W.Limwikrant, K.Higashi, Y.Tozuka, T.Oguchi, K.Yamamoto
    • Journal Title

      Int.J.Pharm

      Volume: 420 Pages: 191-197

    • DOI

      10.1016/j.ijpharm.2011.08.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] NMR investigation of a novel excipient, α-glucosylhesperidin, as a suitable solubilizing agent for poorly water-soluble drugs2011

    • Author(s)
      J. Zhang, Y. Tozuka, H. Uchiyama, K. Higashi, K. Moribe, H. Takeuchi, K. Yamamoto
    • Journal Title

      J. Pharm.Sci

      Volume: 100 Pages: 4421-4431

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Guest molecular size-dependent inclusion complexation of parabens with cholic acid by cogrinding2011

    • Author(s)
      K. Moribe, M. Masaki, R. Kinoshita, J. Zhang, W. Limwikrant, K. Higashi, Y. Tozuka, T. Oguchi, K. Yamamoto
    • Journal Title

      Int. J. Pharm

      Volume: 420 Pages: 191-197

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] NMR Investigation of a Novel Excipient, α-Glicosylhesperidin as a Suitable Solubilizing Agent for Poorly Water-Soluble Drugs2011

    • Author(s)
      J.Zhang, Y.Tozuka, H.Uchiyama, K.Higashi, K.Moribe, H.Takeuchi, K.Yamamoto
    • Journal Title

      Journal of Pharmaceutical Sciemces

      Volume: 100 Pages: 4421-4431

    • DOI

      10.1002/jps.22606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038, KAKENHI-PROJECT-22790041
  • [Journal Article] Structural evaluation of crystalline ternaryγ-cyclodextrin complex2011

    • Author(s)
      K. Higashi, S. Ideura, H. Waraya, K. Moribe, K. Yamamoto
    • Journal Title

      J. Pharm.Sci

      Volume: 100 Pages: 325-333

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Ascorbyl dipalmitate/PEG-lipid nanoparticles as a novel carrier for hydrophobic drugs2010

    • Author(s)
      K. Moribe, S. Maruyama, Y. Inoue, T. Suzuki, T. Fukami, K. Tomono, K. Higashi, Y. Tozuka, K. Yamamoto
    • Journal Title

      Int. J. Pharm

      Volume: 387 Pages: 236-243

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Simultaneous dissolution of naproxen and flurbiprofen from a novel ternary gamma-cyclodextrin complex.2010

    • Author(s)
      K.Higashi, S.Ideura, H.Waraya, W.Limwikrant, K.Moribe, K.Yamamoto
    • Journal Title

      Chem.Pharm.Bull.

      Volume: 58 Pages: 769-772

    • NAID

      130000255846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Ascorbyl dipalmitate/PEG-lipid nanoparticles as a novel carrier for hydrophobic drugs2010

    • Author(s)
      K.Moribe, S.Maruyama, Y.Inoue, T.Suzuki, T.Fukami, K.Tomono, K.Higashi, Y.Tozuka, K.Yamamoto
    • Journal Title

      Int.J.Pharm. 387

      Pages: 236-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Effect of particle size on skin permeation and retention of piroxicam in aqueous suspension2010

    • Author(s)
      K. Moribe, M. Shibata, T. Furuishi, K. Higashi, K. Tomono, K. Yamamoto
    • Journal Title

      Chem. Pharm. Bull

      Volume: 58 Pages: 1096-1099

    • NAID

      130000299822

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Effect of particle size on skin permeation and retention of piroxicam in aqueous suspension2010

    • Author(s)
      K.Moribe, M.Shihata, T.Furuishi, K.Higashi, K.Tomono, K.Yamamoto
    • Journal Title

      Chem.Pharm.Bull.

      Volume: 58 Pages: 1096-1099

    • NAID

      130000299822

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] alicylicacid/γ-cyclodextrin2:1 and 4:1 complex formation by sealed-heating method2010

    • Author(s)
      K. Higashi, Y. Tozuka, K. Moribe, K. Yamamoto
    • Journal Title

      J. Pharm. Sci

      Volume: 99 Pages: 4192-4200

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Simultaneous dissolution of naproxen and flurbiprofen from anovel ternary gamma-cyclodextrin complex2010

    • Author(s)
      K. Higashi, S. Ideura, H. Waraya, W. Limwikrant, K. Moribe, K. Yamamoto
    • Journal Title

      Chem. Pharm. Bull

      Volume: 58 Pages: 769-772

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Prednisolone multicomponent nanoparticle preparation by aerosol solvent extraction system.2009

    • Author(s)
      K.Moribe, M.Fukino, Y.Tozuka, K.Higashi, K.Yamamoto
    • Journal Title

      Int.J.Pharm. 380

      Pages: 201-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Characterization of ofloxacin-oxalic acid complex byPXRD, NMR, and THz spectroscopy2009

    • Author(s)
      W. Limwikrant, K. Higashi, K. Yamamoto, K. Moribe
    • Journal Title

      Int. J. Pharm

      Volume: 382 Pages: 50-55

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Characterization of ofloxacin-oxalic acid complex by PXRD, NMR, and THz spectroscopy2009

    • Author(s)
      W.Limwikrant, K.Higashi, K.Yamamoto, K.Moribe
    • Journal Title

      Int.J.Pharm. 382

      Pages: 50-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Nanoparticle formation from probucol/PVP/sodium alkyl sulfate co-ground mixture2009

    • Author(s)
      C.Wanawongthai, A.Pongpeerapat, K.Higashi, Y.Tozuka, K.Moribe, K.Yamamoto
    • Journal Title

      Int.J.Pharm. 376

      Pages: 169-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Prednisolone multicomponent nanoparticle preparation by aerosol solvent extraction system2009

    • Author(s)
      K. Moribe, M. Fukino, Y. Tozuka, K. Higashi, K. Yamamoto
    • Journal Title

      Int. J. Pharm

      Volume: 380 Pages: 201-205

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Nanoparticle formation from probucol/PVP/sodium alkyl sulfate co-ground mixture2009

    • Author(s)
      C. Wanawongthai, A. Pongpeerapat, K. Higashi, Y. Tozuka, K. Moribe, K. Yamamoto
    • Journal Title

      Int. J.Pharm

      Volume: 376 Pages: 169-75

    • Data Source
      KAKENHI-PROJECT-21590038
  • [Journal Article] Morphology and surface states of colloidal probucol nanoparticles evaluated by atomic force microscopy2008

    • Author(s)
      K. Moribe, C. Wanawongthai, J. Shudo, K. Higashi, K.Yamamoto
    • Journal Title

      Chem.Pharm.Bull 56

      Pages: 878-880

    • NAID

      110006684296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Journal Article] Physicochemical, morphological and therapeutic evaluation of agarose hydrogel particles as a reservoir for basic fibroblast growth factor2008

    • Author(s)
      Moribe, K., Nanizu, N., Izukura, S., Yamamoto, K., Tozuka, Y., Sakurai, M, Ishida, A., 他
    • Journal Title

      Pharm Dev Technol 13

      Pages: 541-547

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500379
  • [Journal Article] Morphology and surface states of solloidal probucol nanoparticles evaluated by atomic force microscopy2008

    • Author(s)
      K. Moribe, C. Wanawongthai, J. Shudo, K. Higashi, K. Yamamoto
    • Journal Title

      Chem. Pharm. Bull. 56

      Pages: 878-880

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Journal Article] Physicochemical, morphological and therapeutic evaluation of agarose hydrogel particles as a reservoir for basic fibroblast growth factor2008

    • Author(s)
      Moribe, K., Nomizu, N., Izukura, S., Yamamoto, K., Tozuka, Y., Sakurai, M., Ishida, A., 他
    • Journal Title

      Pharm Dev Technol 13

      Pages: 541-547

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500379
  • [Journal Article] Drug nanoparticle formation from Drug/HPMC/SDS ternary ground mixtures2006

    • Author(s)
      Moribe K., Pongpeerapat A., Tozuka Y., Yamamoto K.
    • Journal Title

      Pharmazie 61

      Pages: 97-101

    • Data Source
      KAKENHI-PROJECT-16790031
  • [Journal Article] Molecular interaction among probucol/PVP/SDS multicomponent system investigated by solid-state NMR.2006

    • Author(s)
      Pongpeerapat A., Higashi K., Tozuka Y., Moribe, K., Yamamoto, K.
    • Journal Title

      Pharm. Res. 23

      Pages: 2566-2574

    • Data Source
      KAKENHI-PROJECT-16790031
  • [Journal Article] Formation and stability of drug nanoparticles obtained from drug/PVP/SDS ternary ground mixture2004

    • Author(s)
      Pongpeerapat A., Itoh K., Tozuka Y., Moribe K., Oguchi T., Yamamoto K.
    • Journal Title

      Journal of Drug Delivery Science and Technology 14・6

      Pages: 441-447

    • Data Source
      KAKENHI-PROJECT-16790031
  • [Presentation] Eudragit E POの構造がfelodipineの結晶化抑制作用に及ぼす影響2022

    • Author(s)
      向出 彩華, 植田 圭祐, 東 顕二郎, 森部 久仁一
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] Eudragit E POの液中構造が薬物の結晶成長抑制作用に及ぼす影響2021

    • Author(s)
      向出 彩華,植田 圭祐, 東 顕二郎, 森部 久仁一
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] Mechanistic and structural understanding of drug/excipients in the formulation to develop functional pharmaceutical product and to assure the quality2021

    • Author(s)
      Kunikazu Moribe
    • Organizer
      1st Bandung International Teleconference on Pharmacy (BITP)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] Eudragit Eの液中構造がフェロジピンの結晶成長抑制作用に及ぼす影響2021

    • Author(s)
      向出 彩華, 植田 圭祐, 東 顕二郎, 森部 久仁一
    • Organizer
      日本薬剤学会 第36年会
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] Eudragit E POの液中構造がフェロジピンの結晶化抑制作用に及ぼす影響2021

    • Author(s)
      向出 彩華, 植田 圭祐, 東 顕二郎, 森部 久仁一
    • Organizer
      第38回製剤と粒子設計シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] 製剤の液中物性分析 ‐現象を理解するための構造評価‐2021

    • Author(s)
      森部久仁一
    • Organizer
      創剤研究コンソーシアム 第6回オンライン創剤技術セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] 溶液NMR測定を用いたPVPによる薬物結晶核生成抑制メカニズムの評価2020

    • Author(s)
      山本 根生、植田 圭祐、東 顕二郎、森部 久仁一
    • Organizer
      日本薬剤学会第35年会
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] Eudragit E POの液中構造が薬物の結晶化抑制作用に及ぼす影響2020

    • Author(s)
      向出 彩華, 植田 圭祐, 東 顕二郎, 森部 久仁一
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K06985
  • [Presentation] 調製条件がglibenclamide非晶質ナノ粒子の物理的安定性に及ぼす影響2020

    • Author(s)
      東 顕二郎、森川  千佳子、植田 圭祐、森部 久仁一
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] Preparation of amorphous nanoparticles for drugs with mid-molecular weight by wet bead milling and its characterization2019

    • Author(s)
      Chen, Z., Ueda, K., Higashi, K., Moribe, K.
    • Organizer
      The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] Effect of molecular state of ternary solid dispersion on the physical property and stability of amorphous drug nanoparticles formed by aqueous dispersion2019

    • Author(s)
      Zhao, Z., Katai, H., Ueda, K., Higashi, K., Moribe, K.
    • Organizer
      The 1st Pharmaceutial Sciences Asia Conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] Effect of surfactant in ternary solid dispersion on the formation of amorphous probucol nanoparticles by aqueous dispersion2019

    • Author(s)
      Zhao, Z., Ueda, K., Higashi, K., Moribe, K.
    • Organizer
      The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] Molecular-level understanding of stabilization mechanism of amorphous cyclosporin A nanosuspension prepared by wet bead milling with Pluronic F1272018

    • Author(s)
      Ziqiao Chen, Keisuke Ueda, Kenjirou Higashi, Kunikazu Moribe
    • Organizer
      第35回製剤と粒子設計シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] 分子製剤学の視点に基づく医薬品の構造及び機構解明2018

    • Author(s)
      森部久仁一
    • Organizer
      薬の未来を考える記念シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] 難溶性薬物Nobiletinの封入脂質ナノ粒子製剤の調製と経口製剤としての有用性の評価2018

    • Author(s)
      松尾 聖羅, 岩尾 康範, 東 顕二郎, 森部 久仁一, 金子 雪子, 木村 晋一郎, 近藤啓
    • Organizer
      製剤機械技術学会第28回大会 (大阪)
    • Data Source
      KAKENHI-PROJECT-17K08455
  • [Presentation] Effect of preparation method of ternary solid dispersion on the evolution of amorphous probucol nanoparticles formed after aqueous dispersion2018

    • Author(s)
      Zhijing Zhao, Hiroaki Katai, Keisuke Ueda, Kenjirou Higashi, Kunikazu Moribe
    • Organizer
      製剤機械技術学会第28回大会
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] コアシェル構造を有するオレイン酸コレステリル/g-シクロデキストリンナノ粒子の調製2018

    • Author(s)
      石本 有沙, 植田 圭祐, 笹子 浩史, 東 顕二郎, 神山 和夫, 森部 久仁一
    • Organizer
      第35回シクロデキストリンシンポジウム
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] Oral formulation development of lipid nanoparticles encapsulated nobiletin, a poorly water-soluble compound2018

    • Author(s)
      Seira Matsuo, Kenjirou Higashi, Kunikazu Moribe, Yukiko Kaneko, Shin-ichiro Kimura, Shigeru Itai, Yasunori Iwao, Hiromu Kondo
    • Organizer
      6th International Conference on Pharmaceuticals, Nutraceuticals and Cosmetic Science 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08455
  • [Presentation] Preparation of cholesteryl oleate/g-cyclodextrin nanoparticles by solvent diffusion method2018

    • Author(s)
      Ishimoto, A., Ueda, K., Higashi, K., Sasako, H., Koyama, K., Moribe, K.
    • Organizer
      The 19th International Cyclodextrin Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06592
  • [Presentation] Eudragit Eの液中構造が薬物可溶化能に及ぼす影響2018

    • Author(s)
      岡本 裕太、植田 圭祐、東 顕二郎、森部 久仁一
    • Organizer
      日本薬剤学会 製剤創剤セミナー
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Application of AFM for structural and morphological evaluation of drug-incorporated nanoparticles2017

    • Author(s)
      Moribe, K., Egami, K., Takahashi, N., Ueda K., Higashi, K.
    • Organizer
      Gordon Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] AFMを用いた水溶液中におけるEudragit® Eのナノ構造体評価2017

    • Author(s)
      岡本 裕太, 植田 圭祐, 東 顕二郎, 森部 久仁一
    • Organizer
      第61回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Glibenclamide非晶質ナノ粒子の構造評価:HPMC添加方法の影響2017

    • Author(s)
      東 顕二郎, 與那城 葉月、 植田 圭祐, 森部 久仁一、伊藤 努武、桝飛雄真、伊藤雅隆、野口修治
    • Organizer
      第34回製剤と粒子設計シンポジウム計シンポジウム
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] 機能性製剤の開発に貢献する添加剤2017

    • Author(s)
      森部 久仁一
    • Organizer
      第16回 医薬品添加剤セミナー
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Cryo-TEM及びAFMによる脂質ナノ粒子の構造解析2017

    • Author(s)
      松尾聖羅, 岩尾 康範, 東 顕二郎,森部 久仁一, 木村 晋一郎, 板井 茂
    • Organizer
      第42年会製剤・創剤セミナー (淡路島)
    • Data Source
      KAKENHI-PROJECT-17K08455
  • [Presentation] 分子レベルからデザイン!超分子構造体を基盤とした固体医薬品製剤の開発2017

    • Author(s)
      東 顕二郎、植田 圭祐、森部 久仁一
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] Characterization of glibenclamide amorphous nanoparticles prepared by antisolvent method: Effect of hypromellose addition method2017

    • Author(s)
      Higashi, K., Yonashiro, H., Ueda K., Itoh, T., Itoh, Masataka, Masu, H., Noguchi, S., Moribe, K.
    • Organizer
      Asian federation pharmaceutical sciences 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] 微粒子製剤の調製と構造評価2017

    • Author(s)
      森部久仁一
    • Organizer
      特別講演会「DDSの現状と将来」
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Cryo-TEM及びAFMによる脂質ナノ粒子の構造解析2017

    • Author(s)
      松尾聖羅, 岩尾 康範, 東 顕二郎,森部 久仁一, 木村 晋一郎, 板井 茂
    • Organizer
      第34回製剤と粒子設計シンポジウム (小倉)
    • Data Source
      KAKENHI-PROJECT-17K08455
  • [Presentation] Characterization of amorphous cyclosporin A nanosuspension prepared by wet bead milling with poloxamer 4072017

    • Author(s)
      Ziqiao CHEN, Keisuke UEDA, Kenjirou HIGASHI, Kunikazu MORIBE
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] 分光法及び顕微鏡法を用いた薬物ナノ懸濁液の構造・分子状態の直接評価2017

    • Author(s)
      東 顕二郎, 植田 圭祐, 森部 久仁一
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      宮城
    • Year and Date
      2017-03-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] 初期の薬物結晶形が湿式粉砕したナノ粒子の物性に及ぼす影響2016

    • Author(s)
      森部 久仁一, 黒岩 洋佑, 植田 圭祐, 東 顕二郎, 山本 恵司
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] Supersaturation strategy for enhanced absorption of poorly water-soluble drugs2016

    • Author(s)
      Moribe, K.
    • Organizer
      2nd Int. Seminar Pharm. Sci. Tech
    • Place of Presentation
      Jatinangor, Indonesia
    • Year and Date
      2016-11-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Supersaturation strategy for enhanced absorption of poorly water-soluble drugs2016

    • Author(s)
      Moribe, K.
    • Organizer
      FAPA2016
    • Place of Presentation
      Bangkok, Thaniland
    • Year and Date
      2016-11-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] AFM observation of morphological changes of doxorubicin-loaded liposomes2016

    • Author(s)
      東 顕二郎, 高橋 尚樹, 植田 圭祐, 山本 恵司, 森部 久仁一
    • Organizer
      第59回顕微鏡学会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2016-11-18
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] 機能性製剤の創製に貢献する添加物2016

    • Author(s)
      森部 久仁一
    • Organizer
      第43回 日本毒性学会学術年会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-06-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Effect of solid properties on drug dissolution from the solid formulation2016

    • Author(s)
      Moribe, K.
    • Organizer
      Asian Graduate Congress on Pharmaceutical Technology
    • Place of Presentation
      Singapore, Singapore
    • Year and Date
      2016-07-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] AFM及びcryo-TEMを用いたドキソルビシン封入リポソームの形態評価2016

    • Author(s)
      森部 久仁一、高橋 尚希、植田 圭祐、東 顕二郎、山本 恵司
    • Organizer
      第32回日本DDS学会学術集会
    • Place of Presentation
      静岡
    • Year and Date
      2016-06-30
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Characterization of the mechanism of drug dissolution enhancement by saccharin addition from phenytoin/Eudragit E PO solid dispersion2016

    • Author(s)
      Higashi, K., Ueda, K., Kanaya, H., Yamamoto, K., Moribe, K.
    • Organizer
      58th Annual International Industrial Pharmaceutical Research and Development Conference
    • Place of Presentation
      Madison,USA
    • Year and Date
      2016-06-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] 3 成分 γ-シクロデキストリン複合体の溶解特性に及ぼすゲスト薬物の影響2016

    • Author(s)
      劉 楠, 植田 圭祐, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 固体分散体からの薬物溶出に影響を及ぼす因子2016

    • Author(s)
      森部 久仁一
    • Organizer
      オレオナノサイエンス部会シンポジウム2016
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08190
  • [Presentation] Indomethacinナノ懸濁液中における薬物結晶形の直接評価2015

    • Author(s)
      黒岩 洋佑, 植田 圭祐, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      第32回製剤と粒子設計シンポジウム
    • Place of Presentation
      豊橋
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] Aggregation and crystallization behavior of probucol from the ternary spray-dried sample solution evaluated by AFM2015

    • Author(s)
      Moribe, K., Egami, K., Higashi, K., Ueda, K., Yamamoto, K.
    • Organizer
      2015AAPS Annual Meeting and Exposition
    • Place of Presentation
      Oralnd USA
    • Year and Date
      2015-10-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] チューブ状及びロッド状構造を形成する ASC-DP ナノ粒子の物性評価2015

    • Author(s)
      東 顕二郎, 重久 友紀, 山本 恵司, 森部 久仁一
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 懸濁ナノ粒子中のindomethacin結晶形の直接評価2015

    • Author(s)
      黒岩 洋佑, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15K07885
  • [Presentation] Control of drug dissolution rate by crystalline ternary g-cyclodextrin complex formation2015

    • Author(s)
      Liu, N., Higashi, K., Yamamoto, K., Moribe, K.
    • Organizer
      Joint Conference of 8th Asian Cyclodextrin Conference and 32nd Cyclodextrin Symposium
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] Solid state NMR study of three polymorphs of SA/(PEG/g-CD-PPRX) complex2015

    • Author(s)
      Higashi, K., Takamizawa, M., Katai, H., Yamamoto, K., Moribe, K.
    • Organizer
      Joint Conference of 8th Asian Cyclodextrin Conference and 32nd Cyclodextrin Symposium
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 混合粉砕及び加熱処理によるPEG/a-CD-PPRXへの薬物封入2015

    • Author(s)
      小川 茉里奈, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 3種類のサリチル酸/(PEG/g-CD-PPRX)複合体多形中におけるサリチル酸の溶解性及び分子状態評価2014

    • Author(s)
      高見澤 誠, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      第31回シクロデキストリンシンポジウム
    • Place of Presentation
      島根
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 3種類のサリチル酸-擬ロタキサン複合体多形からの薬物溶出性評価2014

    • Author(s)
      高見澤 誠, 東 顕二郎, 森部 久仁一, 山本 恵司
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      埼玉
    • Year and Date
      2014-05-20
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 有機ナノチューブに封入されたIbuprofenの溶解性評価2014

    • Author(s)
      劉 楠、東 顕二郎、森部 久仁一、丁 武孝、亀田 直弘、増田 光俊、清水 敏美、山本 恵司
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 混合粉砕及び加熱によるサリチル酸のPEG/a-CD-PPRXへの封入2014

    • Author(s)
      小川 茉里奈, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      第31回シクロデキストリンシンポジウム
    • Place of Presentation
      島根
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 薬物結晶化抑制作用に及ぼすHPMC-AS置換基比率の影響:溶液NMRによる評価2013

    • Author(s)
      植田圭祐、東顕二郎、森部久仁一、山本恵司
    • Organizer
      製剤機械技術学会 第23回大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] 異なる内側表面構造をもつ有機ナノチューブへのIbuprofenの封入検討2013

    • Author(s)
      劉 楠、東 顕二郎、森部 久仁一、丁 武孝、亀田 直弘、増田 光俊、清水 敏美、山本 恵司
    • Organizer
      日本薬剤学会 第28年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 置換基比率の異なる各種HPMC-ASによる結晶化抑制作用の比較2013

    • Author(s)
      植田圭祐、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第30回 製剤と粒子設計シンポジウム
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] Solution NMR study of permeation mechanism of carbamazepine from supersaturated and solubilized solution2013

    • Author(s)
      K. Ueda, K. Moribe, K. Higashi, K. Yamamoto
    • Organizer
      The 5th Asian Arden Conference
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] ASC-DP含有率の高いASC-DP/DSPE-PEGナノ微粒子の調製及び構造評価2013

    • Author(s)
      設樂 竜平、壬生 総子、東 顕二郎、森部 久仁一、山本 恵司
    • Organizer
      日本薬剤学会 第28年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 過飽和溶液中におけるHPMC及びPVPによるフェニトイン誘導体結晶化抑制メカニズムの解明2013

    • Author(s)
      大塚直哉、植田圭祐、清水梢、片山和明、熊本卓哉、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第30回 製剤と粒子設計シンポジウム
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] ASC-DPナノ微粒子形成に及ぼすDSPE-PEGの影響2013

    • Author(s)
      設樂 竜平、壬生 総子、東 顕二郎、森部 久仁一、山本 恵司
    • Organizer
      第57回 日本薬学会関東支部
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25460032
  • [Presentation] 混合粉砕と加熱によるCD-polypseudorotaxane同士で形成される空間への薬物封入2012

    • Author(s)
      並木祥恵、WareeLimwikrant、東顕二郎、森部久仁一、山本恵司
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-23659017
  • [Presentation] 過飽和溶液中でのHPMC-ASによるCarbamazepine結晶化抑制メカニズムの解明2012

    • Author(s)
      植田圭祐、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第29回製剤と粒子設計シンポジウム
    • Place of Presentation
      豊橋
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] FSM細孔内のインドメタシン着色メカニズムの検討2012

    • Author(s)
      東顕二郎、田邉修一、WareeLimwikrant、森部久仁一、山本恵司
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道
    • Data Source
      KAKENHI-PROJECT-23659017
  • [Presentation] 混合粉砕によるpiroxicamのPEG/-CD-polypseudorotaxaneへの封入2012

    • Author(s)
      並木祥恵、Waree Limwikrant、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第29回シクロデキストリンシンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23659017
  • [Presentation] 1H-NMRによるCarbamazepine/HPMC-AS過飽和溶液中の薬物分子状態の解明2012

    • Author(s)
      植田圭祐、Waree Limwikrant、東顕二郎、森部久仁一、山本恵司
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] 非晶質製剤及びナノ結晶製剤を利用した難溶性薬物の溶解性改善2012

    • Author(s)
      森部久仁一
    • Organizer
      第8回ナノ製剤技術研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] 混合粉砕によるpiroxicamのPEG/・-CD-polypseudorotaxaneへの封入2012

    • Author(s)
      並木祥恵、WareeLimwikrant、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第29回シクロデキストリンシンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23659017
  • [Presentation] 有機ナノチューブを用いたヒドロコルチゾンの溶解性改善2012

    • Author(s)
      牧島隆史、東顕二郎、WareeLimwikrant、森部久仁一、丁武考、増田光俊、清水敏美、山本恵司
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道
    • Data Source
      KAKENHI-PROJECT-23659017
  • [Presentation] 混合粉砕と加熱によるCD-polypseudorotaxane 同士で形成される空間への薬物封入2012

    • Author(s)
      並木祥恵、Waree Limwikrant、東顕二郎、森部久仁一、山本恵司
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-23659017
  • [Presentation] Structural evaluation of probucol nano suspension by AFM2011

    • Author(s)
      K. Moribe, W. Limwikrant, K. Higashi, K. Yamamoto
    • Organizer
      AsianFederation for Pharmaceutical Sciences Conference 2011. BO-005
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Structural evaluation of probucol nano suspension by AFM2011

    • Author(s)
      K.Moribe, W.Limwikrant, K.Higashi, K.Yamamoto.
    • Organizer
      Asian Federation for Pharmaceutical Sciences Conference 2011
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2011-12-11
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] 混合粉砕による薬物のナノ粒子化と製剤応用2011

    • Author(s)
      森部久仁一
    • Organizer
      第48回 薬剤学懇談会研究討論会
    • Place of Presentation
      かみの山、山形(招待講演)
    • Year and Date
      2011-07-07
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Physicochemical characterization of drug nanoparticles in solid and suspended states2011

    • Author(s)
      K. Moribe
    • Organizer
      Particulate Processes in the Pharmaceutical Industry III
    • Place of Presentation
      Goldcoast, Australia
    • Year and Date
      2011-07-27
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] AFM測定による製剤のナノ構造評価2011

    • Author(s)
      森部久仁一
    • Organizer
      日本薬剤学会第26年会
    • Place of Presentation
      船堀、東京
    • Year and Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] くすりの溶解について2011

    • Author(s)
      森部久仁一
    • Organizer
      日本薬剤学会経口吸収フォーカスグループ第1回合宿討論会
    • Place of Presentation
      沼津
    • Year and Date
      2011-02-15
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Preparation and physicochemical characterization of ofloxacin-dicarboxylic acid complex2011

    • Author(s)
      K.Moribe, W.Limwikrant, K.Higashi, K.Yamamoto
    • Organizer
      International Congress of Analytical Sciences 2011
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Structural investigation of supersaturated solution from solid dispersion of mefenamic acid and Eudragit EPO2011

    • Author(s)
      K. Moribe, T. Kojima, K. Higashi, T. Suzuki, K. Tomono., K. Yamamoto
    • Organizer
      International Symposium on BA/BE of Oral Drug Products. P11
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2011-07-01
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Physicochemical characterization of drug nanoparticles in solid and suspended states2011

    • Author(s)
      K.Moribe
    • Organizer
      Particulate Processesin the Pharmaceutical Industry III
    • Place of Presentation
      Gold Coast, Australia(招待講演)
    • Year and Date
      2011-07-27
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] 溶液中での薬物及び添加剤の物性評価2011

    • Author(s)
      森部久仁一
    • Organizer
      日本薬剤学会経口吸収フォーカスグループ第2回合宿討論会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-06
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] FM測定による製剤のナノ構造評価2011

    • Author(s)
      森部久仁一
    • Organizer
      日本薬剤学会第26年会、シンポジウム「界面化学で理解する経口吸収」
    • Place of Presentation
      東京
    • Year and Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] アスコルビン酸誘導体/DSPE-PEGナノ微粒子の構造評価及び細胞障害性2010

    • Author(s)
      森部久仁一, 壬生総子, 齋藤謙悟, 東顕二郎, 白澤浩, 山本恵司
    • Organizer
      第26回日本DDS学会2-B-23
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] EVALUATION OF DRUG NANOPARTICLES IN SOLID AND SDSPENSION BY HIGH RESOLUTION SEM AND LIQUID AFM2010

    • Author(s)
      K.Moribe, C.Wanawongthai, K.Higashi, K.Yamamoto
    • Organizer
      AAPS-FIP World Congress 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] 3成分シクロデキストリセ複合体形成によるflurbiprofenの溶出制御2010

    • Author(s)
      東顕二郎, 出浦小織, 森部久仁一, 山本恵司
    • Organizer
      第27回シクロデキストリンシンポジウム
    • Place of Presentation
      金沢市文化ホール
    • Year and Date
      2010-09-06
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] 薬物/(PEG-v-CD-polypseudorotaxane)複合体の構造変化が薬物の分子状態に及ぼす影響2010

    • Author(s)
      藁谷美香, 東顕二郎, 森部久仁一, 山本恵司
    • Organizer
      第27回シクロデキストリンシンポジウム
    • Place of Presentation
      金沢市文化ホール
    • Year and Date
      2010-09-06
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Evaluation of Drug Nanoparticles in Aqueous Solution by AFM Image and Force Curve Analysis2010

    • Author(s)
      K. Moribe, A. Ogino, K. Higashi, K. Yamamoto
    • Organizer
      FIP Pharmaceutical Sciences 2010 World Congress, New Orleans, M1329
    • Place of Presentation
      LA, USA
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Drug-loaded ascorbyl dipalmitate/DSPE-PEG nanoparticulate system2009

    • Author(s)
      S. Maruyama, K. Moribe, T. Suzuki, K. Tomono, K. Higashi, K. Yamamoto
    • Organizer
      11^<th>International Symposium on Microencapsulation
    • Place of Presentation
      Naogya,Japan
    • Year and Date
      2009-09-30
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Ascorbyl dipalmitate/DSPE-PEG nanoparticulate system as a novel drug delivery carrier2009

    • Author(s)
      K. Moribe, S. Maruyama, K. Higashi, K. Yamamoto
    • Organizer
      2009 American Association Pharmaceutical Sciences Annual Meeting and Exposition,W4246, Los angles
    • Place of Presentation
      California, USA
    • Year and Date
      2009-11-11
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] A Novel Complex Formation of salicylic acid and Y-cyclodextrin-polypseudorotaxane2009

    • Author(s)
      K. Higashi, H. Waraya, K. Moribe, K. Yamamoto
    • Organizer
      Asian Federation for Pharmaceutical Sciences
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2009-10-17
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] テラヘルツスペクトル分光法によるオフロキサシン-シュウ酸複合体形成の評価2009

    • Author(s)
      Limwikrant Waree, 東顕二郎, 森部久仁一, 山本恵司
    • Organizer
      日本薬学会第129回年会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] Physicochemical characterization of phenytoin derivative nanoparticles prepared by cogrinding2009

    • Author(s)
      K. Moribe, A. Ogino, K. Higashi, K. Yamamoto
    • Organizer
      Pharmaceutical Sciences
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2009-10-17
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] テラヘルツスペクトル分光法によるオフロキサシン-シュウ酸複合体形成の評価2009

    • Author(s)
      Limwikrant Waree、東顕二郎、森部久仁一、山本恵司
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] PHYSICOCHEMICAL CHARACTERIZATION OF PHENYTOIN DERIVATIVE NANOPARTICLES PREPARED BY COGRINDING2009

    • Author(s)
      K.Moribe, A.Ogino, K.Higashi, K.Yamamoto
    • Organizer
      Asian Federation of Pharmaceutical Science
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2009-10-17
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] Drug-loaded Ascorbyl dipalmitate/DSPE-PEG nanoparticulate system2009

    • Author(s)
      K.Moribe, S.Maruyama, K.Higashi, Y.Tozuka, K.Yamamoto
    • Organizer
      17^<th> International Symposium of Microencapsulation
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-09-29
    • Data Source
      KAKENHI-PROJECT-21590038
  • [Presentation] テラヘルツ・遠赤外吸収スペクトル測定によるエテンザミド-チオ尿素複合体形成の評価2008

    • Author(s)
      森部久仁一、Limwikrant Waree、東顕二郎、山本恵司、畑晶之、笹倉大督
    • Organizer
      第25回製剤と粒子設計シンポジウム
    • Place of Presentation
      琵琶湖ホテル
    • Year and Date
      2008-11-13
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] テラヘルツスペクトル測定によるテオフィリンとジカルボン酸類のcocrystal形成の評価2008

    • Author(s)
      Limwikrant Waree、森部久仁一、田中耕一郎、東顕二郎、山本恵司
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] 医薬品と尿素化合物との複合体形成:テラヘルツ分光法による評価2007

    • Author(s)
      Limwikrant Waree, 森部 久仁一, 安藤 茂, 東顕 二郎, 山本 恵司, 畑 昌之
    • Organizer
      第24回製剤と粒子設計シンポジウム
    • Place of Presentation
      浜松アクトシティー
    • Year and Date
      2007-11-14
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] 医薬品と尿素化合物との複合体形成 : テラヘルツ分光法による評価2007

    • Author(s)
      Limwikrant Waree、森部久仁一、安藤茂、東顕二郎、山本恵司、畑晶之
    • Organizer
      第24回製剤と粒子設計シンポジウム
    • Place of Presentation
      浜松アクトシティー
    • Year and Date
      2007-11-14
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] テラヘルツ分光法による尿素及びチオ尿素と医薬品との複合体形成の評価2007

    • Author(s)
      森部久仁一、安藤茂、畑晶之、戸塚裕一、山本恵司
    • Organizer
      日本薬剤学会第22年会
    • Place of Presentation
      大宮ソニックホール
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19590035
  • [Presentation] HPMC及びPVPの薬物結晶化抑制機構の違いが膜透過性に及ぼす影響

    • Author(s)
      大塚 直哉, 植田 圭祐, 清水 梢, 片川 和明, 熊本 卓也, 東 顕二郎, 山本 恵司, 森部 久仁一
    • Organizer
      製剤機械技術学会第24回大会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-10-08 – 2014-10-09
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] Phenytoin/Eudragit S100 固体分散体の物性と溶出挙動との関連

    • Author(s)
      林大基、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第57回 日本薬学会関東支部大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] HPMC-AS の薬物結晶化抑制作用に及ぼす胆汁酸及び脂質の影響

    • Author(s)
      植田 圭祐, 東 顕二郎, 片岡 誠, 山下 伸二, 山本 恵司, 森部 久仁一
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-24590045
  • [Presentation] Phenytoin過飽和溶液のCaco-2細胞透過改善メカニズムの解明

    • Author(s)
      大塚直哉、植田圭祐、清水梢、片山和明、熊本卓哉、東顕二郎、森部久仁一、山本恵司
    • Organizer
      第57回 日本薬学会関東支部大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590045
  • 1.  HIGASHI Kenjirou (40451760)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 136 results
  • 2.  YAMAMOTO Keiji (50110341)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 85 results
  • 3.  植田 圭祐 (40755972)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 28 results
  • 4.  MIYAZAKI Masaru (70166156)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  LIMWIKRANT Waree (50595907)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 6.  ISHIDA Atsushi (70334183)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  Itai Shigeru (80453059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  畑 晶之 (50241972)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 9.  岩尾 康範 (30433022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 10.  近藤 啓 (10825110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  木村 晋一郎 (20791338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  WANAWONGTHAI Chalermphon
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  丸山 直
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUZUKI Toyofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  SEKINE Shuichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  HORIE Toshiharu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  戸塚 裕一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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