Nakamura Shiro 中村志郎

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NAKAMURA Shiro 中村志郎

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Researcher Number	50271185
Other IDs
Affiliation (Current)	2022: 大阪医科薬科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021: 大阪医科薬科大学, 医学部, 教授 2020: 大阪医科大学, 医学部, 教授 2015 – 2019: 兵庫医科大学, 医学部, 教授 2002 – 2004: 大阪市立大学, 大学院・医学研究科, 講師 2001: 大阪市立大学, 大学院・医学研究科, 助手 1995 – 2000: 大阪市立大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / Basic Section 47040:Pharmacology-related Except Principal Investigator Gastroenterology / Gastroenterology
Keywords	Principal Investigator クローン病 / 炎症性腸疾患 / 潰瘍性大腸炎 / 肉芽腫 / ケモカイン / NUDT15 / チオプリン / 個別化医療 / 遺伝子多型 / 細胞接着分子 … More / リンパ管 / 細胞培養分子 / リンパ球 / B細胞 / 形質細胞 / 増殖 / 免疫組織化学 / IBD(炎症性腸疾患) / Ki67 / basal plasmacytosis / plasmacytosis / 腸間膜リンパ節 / inflammatory bowel disease / ulcerative colitis / Crohn's disease / lymphocyte / B cell / plasma cell / prolifaration / immunohistochemistry / オーダーメイド医療 / Pharmacogenetics / ゲノム薬理学 / 遺伝子多型検査 / 遺伝薬理学 / ファーマコゲノミクス / 白血球減少症 … More Except Principal Investigator クローン病 / 炎症性腸疾患 / 粘膜免疫 / 肉芽腫 / Crohn's disease / 潰瘍性大腸炎 / 炎症性陽疾患 / Th1細胞 / 特異抗原 / Th1 / クローナリティー / T細胞レセプター / clonality / 腸間膜リンパ節 / 粘膜固有層リンパ球 / INFLAMMATORY BOWEL DISEASE / CROHN'S DISEASE / MUCOSAL IMMUNITY / GRANULOMA / TH1 CELLS / SPECIFIC ANTIGENS / ケモカイン / T細胞 / 樹状細胞 / ホーミングレセプター / MAdCAM-1 / 疾患特異抗原 / T細胞抗原レセプター / インテグリン / NKT細胞 / ボーミングレセプター / Chemokines / T cells / Dendritic cells / Homing receptors / 特発性炎症性腸疾患 / 抗原ペプチド / 質量分析 / アミノ酸配列 / 特発生炎症性腸疾患 / HLA-DR / 抗ペプチド / HLA-DP / 免疫吸着カラム / Inflammatory bowel disease / ulcerative colitis / class II MHC / antigenic peptide / tandem mass analysis / amino acid sequence / 疾患感受性遺伝子 / NKX2.3 / 実験動物モデル / 遺伝子改変マウス / NKX2-3 / 感受性遺伝子 Less

チオプリン製剤服用妊婦より産まれた児の副作用とNUDT15遺伝子多型の影響の調査Principal Investigator
- Principal Investigator
  
  中村志郎
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Hyogo Medical University
感受性遺伝子NKX2-3の基礎・臨床的解析による炎症性腸疾患の病態解明と臨床応用
- Principal Investigator
  
  高川哲也
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
Precision medicine using NUDT15 variant for thiopurine therapy in inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  Nakamura Shiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo Medical University
Role of class II MHC bound antigenic peptide in the pathogenesis of inflammatory bowel disease.
- Principal Investigator
  
  OSHITANI Nobuhide
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Mechanism of T/NKT cells activation in granuloma of Crohn's disease
- Principal Investigator
  
  MASTUMOTO Takayuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hyogo College of Medicine
  Osaka City University
Immunohistochemical study of disease-specific immune reaction in inflammatory bowel disease.Principal Investigator
- Principal Investigator
  
  NAKAMURA Shiro
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University Graduate School of Medicine
DISEASE SPECIFIC ANTIGENS AND T CELLS IN INFLAMMATORY BOWEL DISEASES
- Principal Investigator
  
  MATSUMOTO Takayuki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  OSAKA CITY UNIVERSITY MEDICAL SCHOOL
クローン病病変粘膜における肉芽腫起因性細胞性免疫反応の免疫組織化学的研究Principal Investigator
- Principal Investigator
  
  中村志郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
クローン病の腸管粘膜における病変の進展と異所性リンパ装置形成に関する免疫学的研究Principal Investigator
- Principal Investigator
  
  中村志郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University

All 2020 2017 2005 2001 2000

All Journal Article Presentation

[Journal Article] NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases2017
- Author(s)
  佐藤寿行、高川哲也、角田洋一、西尾昭宏、河合幹夫、上小鶴孝二、横山陽子、木田裕子、宮嵜孝子、飯室正樹、樋田信幸、堀和敏、池内浩基、中村志郎
- Journal Title
  
  Intestinal Research
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08976
[Journal Article] NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases2017
- Author(s)
  Sato Toshiyuki、Takagawa Tetsuya、Kakuta Yoichi、Nishio Akihiro、Kawai Mikio、Kamikozuru Koji、Yokoyama Yoko、Kita Yuko、Miyazaki Takako、Iimuro Masaki、Hida Nobuyuki、Hori Kazutoshi、Ikeuchi Hiroki、Nakamura Shiro
- Journal Title
  
  Intestinal Research
  
  Volume: 15 Pages: 328-328
- DOI
  10.5217/ir.2017.15.3.328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08976
[Journal Article] Augmented expression of secondary lymphoid of tissue chemokine and EBIl ligand chemokine in Crohn's disease.2005
- Author(s)
  Kawashima D, Oshitani N, Jinno Y, Watanabe K, Nakamura S, Higuchi K, Arakawa T.
- Journal Title
  
  J Clin Pathol 58
  
  Pages: 1057-1063
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Mycobacterial trehalose 6, 6' -dimycolate preferentially induces type 1 helper T cell responses through signal transducer and activator of transcription 4 protein.2005
- Author(s)
  Oiso R, Fujiwara N, Yamagami H, Maeda S, Matsumoto S, Nakamura S, Oshitani N, Matsumoto T, Arakawa T, Kobayashi K
- Journal Title
  
  MicrobPathogenesis 39
  
  Pages: 35-43
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Mycobacterial trehalose 6,6'-dimycolate preferentially induces type 1 helper T cell responses through signal transducer and activator of transcription 4 protein.2005
- Author(s)
  Oiso R, Fujiwara N, Yamagami H, Maeda S, Matsumoto S, Nakamura S, Oshitani N, Matsumoto T, Arakawa T, Kobayashi K
- Journal Title
  
  MicrobPathogenesis 39
  
  Pages: 35-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease.2005
- Author(s)
  Oshitani N, Watanabe K, Nakamura S, Fujiwara Y, Higuchi K, Arakawa T.
- Journal Title
  
  Int J Mol Med 1
  
  Pages: 407-410
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease.2005
- Author(s)
  Oshitani N, Watanabe K, Nakamura S, Fujiwara Y, Higuchi K, Arakawa T.
- Journal Title
  
  Int J Mol Med 15
  
  Pages: 407-410
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Significance of increased proliferation of immature plasma cells in the appendix of patients with ulcerative colitlis.2005
- Author(s)
  Kawachiya T, Oshitani N, Jinno Y, Watanabe K, Nakamura S, Fujiwara Y, Higuchi K, Maeda K, Nishiguchi Y, Hirakawa K, Matsumoto T, Arakawa T.
- Journal Title
  
  Int J Mol Med 15
  
  Pages: 417-423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Mycobacterial trehalose 6,6'-dimycolate preferentially induces type 1 helper T cell responses through signal transducer and activator of transcription 4 protein.2005
- Author(s)
  Oiso R, Rujiwara N, Yamagami H, Maeda S, Matsumoto S, Nakamura S, Oshitani N, Matsumoto T, Arakawa T, Kobayashi K
- Journal Title
  
  MicrobPathogenesis 39
  
  Pages: 35-43
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Augmented expression of secondary lymphoid tissue chemokine and EBI1 ligand chemokine in Crohn's disease.2005
- Author(s)
  Kawashima D, Oshitani N, Jinno Y, Watanabe K, Nakamura S, Higuchi K, Arakawa T
- Journal Title
  
  J Clin Pathol 58
  
  Pages: 1057-1063
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease.2005
- Author(s)
  Oshitani N, Watanabe K, Nakamura S, Fujiwara Y, Higuchi K, Arakawa T
- Journal Title
  
  Int J Mol Med 15
  
  Pages: 407-410
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Significance of increased proliferation of immature plasma cells in the appendix of patients with ulcerative colitis.2005
- Author(s)
  Kawachiya T, Oshitani N, Jinno Y, Watanabe K, Nakamura S, Fujiwara Y, Higuchi K, Maeda K, Nishiguchi Y, Hirakawa K, Matsumoto T, Arakawa T
- Journal Title
  
  Int J Mol Med 15
  
  Pages: 417-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Journal Article] Augmented expression of secondary lymphoid tissue chemokine and EBII ligand chemokine in Crohn's disease.2005
- Author(s)
  Kawashima D, Oshitani N, Jinno Y, Watanabe K, Nakamura S, Higuchi K, Arakawa T.
- Journal Title
  
  J Clin Pathol 58
  
  Pages: 1057-1063
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590676
[Presentation] 妊娠中チオプリン服用を継続した炎症性腸疾患患者より生まれた児における副作用の検討2020
- Author(s)
  高川哲也, 角田洋一, 小島健太郎, 小柴良司, 藤本晃士, 佐藤寿行, 河合幹夫, 上小鶴孝二, 横山陽子, 宮嵜孝子, 樋田信幸, 渡辺憲治, 中村志郎
- Organizer
  第28回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-19K07113
[Presentation] Thiopurine-induced Leukopenia Is Associated with a Variant in NUDT15, but Not FTO and RUNX1 in Japanese Patients with Inflammatory Bowel Diseases2017
- Author(s)
  Toshiyuki Sato, Tetsuya Takagawa, Shiro Nakamura
- Organizer
  The 5th Annual Meeting of AOCC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08976
[Presentation] Immunohistochemistrical analysis of lymph and antigen presenting cells in Crohn's disease2001
- Author(s)
  Shiro Nakamura
- Organizer
  The 86th Annual meeting of the japanese society of Gastroenterology
- Place of Presentation
  Niigata
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670545
[Presentation] クローン病におけるリンパ管と抗原提示細胞の動態に関する免疫組織化学的研究2000
- Author(s)
  中村志郎, 他
- Organizer
  第86回日本消化器病学会総会
- Place of Presentation
  新潟
- Year and Date
  2000-04-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670545

1. MATSUMOTO Takayuki (10209637)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. WATANABE Kenji (70382041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. 高川哲也 (20444614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. OSHITANI Nobuhide (20231235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. 佐藤寿行 (20836225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Nakamura Shiro 中村 志郎

NAKAMURA Shiro 中村 志郎

Research Projects

Research Products

Co-Researchers

チオプリン製剤服用妊婦より産まれた児の副作用とNUDT15遺伝子多型の影響の調査Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

感受性遺伝子NKX2-3の基礎・臨床的解析による炎症性腸疾患の病態解明と臨床応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Precision medicine using NUDT15 variant for thiopurine therapy in inflammatory bowel diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of class II MHC bound antigenic peptide in the pathogenesis of inflammatory bowel disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of T/NKT cells activation in granuloma of Crohn's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunohistochemical study of disease-specific immune reaction in inflammatory bowel disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DISEASE SPECIFIC ANTIGENS AND T CELLS IN INFLAMMATORY BOWEL DISEASES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クローン病病変粘膜における肉芽腫起因性細胞性免疫反応の免疫組織化学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クローン病の腸管粘膜における病変の進展と異所性リンパ装置形成に関する免疫学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases2017

Author(s)

Journal Title

Data Source

[Journal Article] NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Augmented expression of secondary lymphoid of tissue chemokine and EBIl ligand chemokine in Crohn's disease.2005

Author(s)

Journal Title

Data Source

[Journal Article] Mycobacterial trehalose 6, 6' -dimycolate preferentially induces type 1 helper T cell responses through signal transducer and activator of transcription 4 protein.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Mycobacterial trehalose 6,6'-dimycolate preferentially induces type 1 helper T cell responses through signal transducer and activator of transcription 4 protein.2005

Author(s)

Journal Title

Nakamura Shiro 中村志郎

NAKAMURA Shiro 中村志郎