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Kimura Toru  木村 透

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… Alternative Names

KIMURA Tohru  木村 透

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Researcher Number 50280962
Other IDs
External Links
Affiliation (Current) 2025: 北里大学, 理学部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 北里大学, 理学部, 教授
2012 – 2014: 北里大学, 理学部, 教授
2010 – 2012: 大阪大学, 生命機能研究科, 准教授
2010: 大阪大学, 大学院・生命機能研究科, 准教授
2007 – 2009: Osaka University, 医学系研究科, 准教授 … More
2008: Osaka University, 医学系・研究科, 准教授
2004 – 2006: 大阪大学, 医学系研究科, 助教授
2004: Osaka University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2001 – 2004: 大阪大学, 微生物病研究所, 助教授
1999 – 2000: 大阪大学, 微生物病研究所, 助手
1996 – 1998: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Experimental pathology / Virology / Basic Section 42030:Animal life science-related / Biological Sciences
Except Principal Investigator
General medical chemistry / Basic Section 43050:Genome biology-related / Basic Section 50010:Tumor biology-related / Laboratory animal science / Hematology … More / Otorhinolaryngology / Cell biology / Stem cell biology and medical science / Biological Sciences / Pathological medical chemistry Less
Keywords
Principal Investigator
始原生殖細胞 / ES細胞 / 幹細胞 / 生殖細胞 / PI3K / Wnt / EG細胞 / 幹細胞システム / PTEN / 生殖系列 … More / Aktシグナル / Akt signal / β-catenin signal / ES cell / β-cateninシグナル / germ cell-less / primordial germ cells / Cre / EGFP / Oct-3 / coiled-coil / AIDS / HIV / 減数分裂 / iPS細胞 / 多能性 / 初期化 / 胚性幹細胞 / シグナル伝達 / 転写因子 / SWI/SNF複合体 / クロマチンリモデリング / de novo DNAメチル化 / 性分化 / 配偶子形成 / 有性生殖 / stem cell system / EG cell / primordial germ ce;; / 発癌 / 表皮幹細胞 / stem cell / germ cell / primordial germ cell / P13キナーゼ / tumor suppressor / stem cells / pluripotency / EG cells / クロマチン・リモデリング / germ cell-less遺伝子 / 胚性生殖細胞 / テラトーマ / Pten遺伝子 / 精子形態形成 / 癌抑制遺伝子 / 分化全能性 / loxP system / transgenic mice / 4 gene / TNAP gene / Germ lineage / germ cell-less(gcl)遺伝子 / 生殖質 / loxP系 / loxPシステム / トランスジェニックマウス / 4遺伝子 / TNAP遺伝子 / protein trafficking / Nafl (Nef-associated factor 1) / CD4 downregulation / 活性化T細胞 / Nef結合因子 / SH3ドメイン / Naf1(Nef-associated factor1) / タンパク輸送 / Naf1(Nef-associated factor 1) / Nef / 相互転換 / シグナル / 分化誘導 / 精子形成 / レトロトランスポゾン / PIWIファミリー / マウス / PIWI / 小分子RNA / piRNA / 対合 / 相同染色体 / DNAメチル化 / 分化可塑性 / 中胚葉分化 / 中胚葉誘導 / 胚性幹細胞(ES細胞) / ERKシグナル / 再生医学 / リン酸化シグナル / 生殖幹細胞 / 毛包幹細胞 / 上皮幹細胞 / GSK3β / 間葉系幹細胞 / 軟骨 / Akt / 脱分化 / 組織幹細胞 / リン酸化酵素 / インターフェロン / ISGF3 / p48 / IRF-1 / 転写制御 / 感染 / ウイルス … More
Except Principal Investigator
PTEN / 幹細胞 / 細胞分化 / 精子形成 / DNAメチル化 / 始原生殖細胞 / エピゲノム / エピジェネティクス / GATA-2 / 転写因子 / 胚性幹細胞 / 胚性生殖細胞 / 脱分化 / 生殖細胞 / レトロトランスポゾン / エピゲノム編集 / ゲノムインプリンティング / 代謝産物 / state transition / グリオブラストーマ / 膠芽腫 / AKTシグナル / がん幹細胞 / Totipotency / Primordial germ cells / Chromosome mapping / Teratoma candidate / KO mouse / Testicular teratomas / Mouse / 精巣性奇形腫(テラトーマ) / 生殖細胞増殖 / 生殖細胞特異遺伝子 / マッピング / 奇形腫(テラトーマ) / 分化全能性 / 染色体マッピング / 奇形腫原因遺伝子 / 遺伝子改変マウス / 奇形腫高発系 / マウス / megakaryocyte / erythrocyte / macrophage / embryonic stem cell / transcription factor / hematopoiesis / stem cell / cell differentiation / 転写調節 / 巨核球 / 赤血球 / マクロファージ / 造血システム / Stroma Cell / Gene Regulation / Transcription Factor / Cell Differentiation / Embryonic Stem Cell / Hematopoiesis / Myb転写因子 / GATA転写因子 / 造血 / 分化誘導 / 造血幹細胞 / Oogenesis / Germ cell-less / Embryonic germ cell / Teratoma / Spermatogenesis / Primordial germ cell / 遺伝子破壊 / 奇形腫 / がん抑制遺伝子 / 生殖系列 / 遺伝子ターゲティング / PI3/Aktシグナル伝達系 / convergent extension / PTEN cko マウス / PI3K/Aktシグナル経路 / 蝸牛 / PI3K/Aktシグナル径路 / 有毛細胞 / 感覚上皮予定領域 / 内耳発生 / ほ乳類 / PTEN ckoマウス / Pi3K/Aktシグナル伝達系 / 細胞内情報伝達 / メンブレントラフィック / リソソーム / 非コードRNA / GS細胞 / IAP / 生殖幹細胞 / piRNA / 小分子RNA / germ cell less / 遺伝子ターゲティングマウス / RNAi / mili / 遺伝子操作 / シグナル伝達 / 細胞文化 / インプリンティング / small RNA / インプリンディング / 初期胚 / 遺伝子発現制御 / エピジェネヒィック制御 / germ cell-less(gcl) / Cre / TAT融合タンパク / protein transduction Less
  • Research Projects

    (22 results)
  • Research Products

    (110 results)
  • Co-Researchers

    (26 People)
  •  Exploration and Analysis of Epigenome Control Core Using DNA Methylation Editing Technology

    • Principal Investigator
      関田 洋一
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      Kitasato University
  •  雌雄の生殖細胞の性分化を推進させるクロマチンリモデリング複合体の解析Principal Investigator

    • Principal Investigator
      木村 透
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42030:Animal life science-related
    • Research Institution
      Kitasato University
  •  Elucidation of epigenomic and metabolic control by Akt signaling in the development of cancer stem cells

    • Principal Investigator
      Sekita Yoichi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kitasato University
  •  Reciprocal conversion between germ cells and pluripotent stem cellsPrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kitasato University
  •  マウスPIWIファミリーによる減数分裂期の染色体構造の制御Principal Investigator

    • Principal Investigator
      木村 透
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
      Osaka University
  •  Regulation of cellular function by late endosomal kinase signaling

    • Principal Investigator
      NADA Shigeyuki
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Osaka University
  •  Functional analysis of the PI3K/Akt signaling pathway during the mammalian inner ear development and its application for regenerative medicine

    • Principal Investigator
      MURATA junko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Juntendo University
  •  Analysis of phosphoryl at ionsignals in regulation of stem cell systemPrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  Analysis of germ stem cells and small RNAs

    • Principal Investigator
      MIYAGAWA Satomi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Stem cell biology and medical science
    • Research Institution
      Osaka University
  •  Roles of phosphorylation signals in regulation of stem cell systemsPrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  Mechanisms regulating mouse germline establishment and stem cell systemsPrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  生殖細胞の成立と分化における分子基盤

    • Principal Investigator
      仲野 徹
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Analysis of mouse primordial germ cell development and stem cell systemsPrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  MOLECULAR BASIS OF STEM CELL SYSTEMS AND ITS APPLICATION

    • Principal Investigator
      NAKANO Toru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      OSAKA UNIVERSITY
  •  GENETIC AND DEVELOPMENTAL ANALYSIS OF MECHANISMS UNDERLYING TERATOCARCINOGENESIS IN THE MOUSE GERM CELLS.

    • Principal Investigator
      NOGUCHI Motoko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Shizuoka University
  •  Analysis of molecules involved in mouse primordial germ cell developmentPrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  タンパク導入法を用いた遺伝子欠損の実験的治療

    • Principal Investigator
      NAKANO Toru
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Molecular Mechanisms for Maintaining Stem Cell Immaturity

    • Principal Investigator
      NAKANO Toru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  Manipulation of hematopoietic cells for regenerative medicine

    • Principal Investigator
      NAKANO Toru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  Analysis of molecules involved in mouse primordial germ cell development using transgenic micePrincipal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  Structural and Functional Analysis of Nef Protein of Human Immunodeficiency Virus (HIV)Principal Investigator

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical and Dental University
  •  ウイルス感染による免疫応答異常における、転写制御及びシグナル伝達機構の異常の解析Principal Investigator

    • Principal Investigator
      木村 透
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2015 2014 2013 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] Regulatory Networks in Stem Cells2009

    • Author(s)
      Kimura, Nakano
    • Publisher
      Humana/Springer Press(in press)
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Book] Regulation of stem cell systems by PI3K/Akt signaling2009

    • Author(s)
      Kimura T, and Nakano T.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Book] Regulatory Networks in Stem Cells2009

    • Author(s)
      Kimura, Nakano
    • Total Pages
      9
    • Publisher
      Humana/Springer
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Book] Testicular Teratomas: Back to Pluripotent Stem Cells in Developmental Biology of Neoplastic Growth2005

    • Author(s)
      Kimura T, Murayama K, Nakamura T, Watanabe S, Umehara H, Tomooka M, Nakano T
    • Total Pages
      15
    • Publisher
      Springer, Berlin
    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Human intestinal organoid-derived PDGFRα?+?mesenchymal stroma enables proliferation and maintenance of LGR4?+?epithelial stem cells2024

    • Author(s)
      Chen JunLong、Horiuchi Shinichiro、Kuramochi So、Kawasaki Tomoyuki、Kawasumi Hayato、Akiyama Saeko、Arai Tomoki、Morinaga Kenichi、Kimura Tohru、Kiyono Tohru、Akutsu Hidenori、Ishida Seiichi、Umezawa Akihiro
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 15 Issue: 1 Pages: 16-16

    • DOI

      10.1186/s13287-023-03629-5

    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Journal Article] Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells2023

    • Author(s)
      Akiyama Saeko、Saku Noriaki、Miyata Shoko、Ite Kenta、Nonaka Hidenori、Toyoda Masashi、Kamiya Akihide、Kiyono Tohru、Kimura Tohru、Kasahara Mureo、Umezawa Akihiro
    • Journal Title

      Progress in Molecular Biology and Translational Science

      Volume: 199 Pages: 155-178

    • DOI

      10.1016/bs.pmbts.2023.02.009

    • ISBN
      9780443134111
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Journal Article] Genetic variation in the Y chromosome and sex-biased DNA methylation in somatic cells in the mouse.2023

    • Author(s)
      Batdorj E, AlOgayil N, Galvez JH, Zhuang QK, Bauermeister K, Nagata K, Kimura T, Ward M, Taketo T, Bourque G, and Naumova AK
    • Journal Title

      Mammalian Genome

      Volume: 34 Issue: 1 Pages: 44-55

    • DOI

      10.1007/s00335-022-09970-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Journal Article] Spatiotemporal changes of tissue glycans depending on localization in cardiac aging2023

    • Author(s)
      Itakura Yoko、Hasegawa Yasuko、Kikkawa Yurika、Murakami Yuina、Sugiura Kosuke、Nagai-Okatani Chiaki、Sasaki Norihiko、Umemura Mariko、Takahashi Yuji、Kimura Tohru、Kuno Atsushi、Ishiwata Toshiyuki、Toyoda Masashi
    • Journal Title

      Regenerative Therapy

      Volume: 22 Pages: 68-78

    • DOI

      10.1016/j.reth.2022.12.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-22K06046, KAKENHI-PROJECT-20K17136, KAKENHI-PROJECT-21K19754, KAKENHI-PROJECT-22K11794
  • [Journal Article] Stem cell challenges and opportunities2023

    • Author(s)
      Ite Kenta、Toyoda Masashi、Akiyama Saeko、Enosawa Shin、Yoshioka Saeko、Yukitake Takaaki、Yamazaki-Inoue Mayu、Tatsumi Kuniko、Akutsu Hidenori、Nishina Hiroshi、Kimura Toru、Otani Naoko、Nakazawa Atsuko、Fukuda Akinari、Kasahara Mureo、Umezawa Akihiro
    • Journal Title

      Progress in Molecular Biology and Translational Science

      Volume: 199 Pages: 379-395

    • DOI

      10.1016/bs.pmbts.2023.03.004

    • ISBN
      9780443134111
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Journal Article] Mechanism of promotion of cell reprogramming by AKT signal2023

    • Author(s)
      関田 洋一、木村 透
    • Journal Title

      生化学

      Volume: 95 Issue: 1 Pages: 66-71

    • DOI

      10.14952/SEIKAGAKU.2023.950066

    • ISSN
      0037-1017
    • Year and Date
      2023-02-25
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Journal Article] Switching defective/sucrose non‐fermenting chromatin remodeling complex coordinates meiotic gene activation via promoter remodeling and Meiosin activation in female germline2022

    • Author(s)
      Ito Toshiaki、Ohta Masami、Osada Atsuki、Nishiyama Akira、Ishiguro Kei‐Ichiro、Tamura Tomohiko、Sekita Yoichi、Kimura Tohru
    • Journal Title

      Genes to Cells

      Volume: 28 Issue: 1 Pages: 15-28

    • DOI

      10.1111/gtc.12990

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-22K06046, KAKENHI-PROJECT-21H02954
  • [Journal Article] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2022

    • Author(s)
      Kojima Shin、Shiochi Naoya、Sato Kazuki、Yamaura Mamiko、Ito Toshiaki、Yamamura Nodoka、Goto Naoki、Odamoto Mika、Kobayashi Shin、Kimura Tohru、Sekita Yoichi
    • Journal Title

      Nucleic Acids Research

      Volume: 50 Issue: 9 Pages: 5080-5094

    • DOI

      10.1093/nar/gkac344

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-22K06046
  • [Journal Article] A RUNX?CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes2021

    • Author(s)
      Murakami Koichi、Sasaki Haruka、Nishiyama Akira、Kurotaki Daisuke、Kawase Wataru、Ban Tatsuma、Nakabayashi Jun、Kanzaki Satoko、Sekita Yoichi、Nakajima Hideaki、Ozato Keiko、Kimura Tohru、Tamura Tomohiko
    • Journal Title

      Nature Immunology

      Volume: 22 Issue: 3 Pages: 301-311

    • DOI

      10.1038/s41590-021-00871-y

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07372, KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-16H06279
  • [Journal Article] Five multicopy gene family genes expressed during the maternal-to-zygotic transition are not essential for mouse development2021

    • Author(s)
      Wakabayashi Mizuki、Tamura Shiori、Kanzaki Satoko、Kosugi Mayuko、Yoshimura Yuki、Ito Toshiaki、Nagata Kei、Sato Kazuha、Takada Shuji、Sekita Yoichi、Kimura Tohru
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 534 Pages: 752-757

    • DOI

      10.1016/j.bbrc.2020.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Journal Article] AKT signaling is associated with epigenetic reprogramming via the upregulation of TET and its cofactor, alpha-ketoglutarate during iPSC generation2021

    • Author(s)
      Sekita Y, Sugiura Y, Matsumoto A, Kawasaki Y, Akasaka K, Konno R, Shimizu M, Ito T, Sugiyama E, Yamazaki T, Kanai E, Nakamura T, Suematsu M, Ishino F, Kodera Y, Kohda T, Kimura T.
    • Journal Title

      Stem Cell Res Ther.

      Volume: - Issue: 1 Pages: 510-510

    • DOI

      10.1186/s13287-021-02578-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05374, KAKENHI-PROJECT-19H00978, KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-20K20584
  • [Journal Article] SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline2021

    • Author(s)
      Ito Toshiaki、Osada Atsuki、Ohta Masami、Yokota Kana、Nishiyama Akira、Niikura Yuichi、Tamura Tomohiko、Sekita Yoichi、Kimura Tohru
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 24074-24074

    • DOI

      10.1038/s41598-021-03538-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Journal Article] Involvement of Nlrp9a/b/c in mouse preimplantation development2020

    • Author(s)
      Kanzaki Satoko, Tamura Shiori, Ito Toshiaki, Wakabayashi Mizuki, Saito Koji, Kato Shigeki, Ohta Yasutaka, Sekita Yoichi, Kimura Tohru
    • Journal Title

      Reproduction

      Volume: 160 Issue: 2 Pages: 181-191

    • DOI

      10.1530/rep-19-0516

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06227, KAKENHI-PROJECT-20K07577
  • [Journal Article] Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds.2015

    • Author(s)
      Kimura T et al.
    • Journal Title

      Stem Cells

      Volume: 33 Issue: 1 Pages: 45-55

    • DOI

      10.1002/stem.1838

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390097, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-26112515, KAKENHI-PROJECT-26250025
  • [Journal Article] Induction of Primordial Germ Cell-Like Cells From Mouse Embryonic Stem Cells by ERK Signal Inhibition.2014

    • Author(s)
      Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujikawa K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T.
    • Journal Title

      Stem Cells

      Volume: 32 Issue: 10 Pages: 2668-2678

    • DOI

      10.1002/stem.1781

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24390097, KAKENHI-PROJECT-24500490, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25293067
  • [Journal Article] The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase2014

    • Author(s)
      Mori S, Nada S, Kimura H, Tajima S, Takahashi Y, Kitamura A, Oneyama C, Okada M.
    • Journal Title

      PLos ONE

      Volume: 9(2) Issue: 2 Pages: e88891-e88891

    • DOI

      10.1371/journal.pone.0088891

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22240088, KAKENHI-PROJECT-23370087, KAKENHI-PUBLICLY-24116515, KAKENHI-PROJECT-24659150, KAKENHI-PUBLICLY-25117716, KAKENHI-PROJECT-25650007, KAKENHI-PROJECT-26640078
  • [Journal Article] Induction of pluripotency in primordial germ cells.2011

    • Author(s)
      Kimura, et al.
    • Journal Title

      Histol.Histopatho.

      Volume: (印刷中)

    • NAID

      40019072189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of Tffrogulatory factor 2(Trf2) in trypsinogen5 gene transcription2011

    • Author(s)
      Hayashi H, Kohno T, Yasui K, Murota H, Kimura T, Duncan GS, Nakashima T, Yamamoto K, Katayama. I, Ma. Y, Chua. KJ, Suematsu T, himokawa T, Akira S, Kubo Mak TW, and Matsuyama. T
    • Journal Title

      Proc. Natl. Acad. Sci, USA

      Volume: 108(46) Pages: 18766-18771

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] Induction of pluripotency in primordial germ cells2011

    • Author(s)
      Kimura. T, and Nakano T
    • Journal Title

      Histol. Histopatho

      Volume: 26(5) Pages: 643-650

    • NAID

      40019072189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] Induction of pluripotency in primordial germ cells2011

    • Author(s)
      Kimura, et al.
    • Journal Title

      Histol.Histopatho.

      Volume: 26 Pages: 643-650

    • NAID

      40019072189

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23125508
  • [Journal Article] Induction of pluripotency in primordial germ cells2011

    • Author(s)
      Kimura, et al
    • Journal Title

      Histol.Histopatho.

      Volume: 26 Pages: 643-650

    • NAID

      40019072189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] MVH in piRNA processing and gene silencing of retrotransposons2010

    • Author(s)
      Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Kimura T, Nakatsuji N, Noce T, Sasaki H, and Nakano T
    • Journal Title

      Genes Dev

      Volume: 24(9) Pages: 887-892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] MVH in piRNA Processing and Gene Silencing of Retrotransposons2010

    • Author(s)
      Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T.
    • Journal Title

      Genes Dev. 23

      Pages: 887-892

    • Data Source
      KAKENHI-PROJECT-20610002
  • [Journal Article] Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation2010

    • Author(s)
      Yamano N, Kimura. T, Watanabe-Kushima S, Shinohara. T, and Nakano T
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 392(3) Pages: 311-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] Associations between PIWI Proteins and TDRD1/ MTR-1 are critical for integrated subcellular localization in murine male germ cells2009

    • Author(s)
      Kojima K, Kuramochi-Miyagawa S, Chuma S, Tanaka T, Nakatsuji N, Kimura T, and Nakano T
    • Journal Title

      Genes Cells

      Volume: 14(10) Pages: 1155-1165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Journal Article] Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.2009

    • Author(s)
      Kojima K.Kuramochi-Miyagawa S.Chuma S.Tanaka T.Nakatsuji N.Kimura T.Nakano T.
    • Journal Title

      Genes to Cells. 14(10)

      Pages: 1155-1165

    • Data Source
      KAKENHI-PROJECT-20610002
  • [Journal Article] PI3K/Akt signaling as a key regulatory pathway for chondrocyte terminal differentiation2008

    • Author(s)
      Kita K, Kimura T, Nakamura N, Yoshikawa H, and Nakano T.
    • Journal Title

      Genes Cells 13(8)

      Pages: 839-850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes2008

    • Author(s)
      Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M , Asada N, Kojima K, Yamaguchi Y, Ijiri T, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, and Nakano T.
    • Journal Title

      Genes Dev 22(7)

      Pages: 908-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] Effects of Akt signaling on nuclear reprogramming2008

    • Author(s)
      Nakamura T, Inoue K, Ogawa S, Umehara H, Ogonuki N, Miki H, Kimura T, Ogura A, and Nakano T.
    • Journal Title

      Genes Cells 13(12)

      Pages: 1269-1277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] AKT signaling promotes derivation of embryonic germ cells form primordial germ cells2008

    • Author(s)
      Kimura T, Tomooka M, Yamano N, Murayama K, Matoba S, Umehara H, Kanai Y, and Nakano T.
    • Journal Title

      Development 135(5)

      Pages: 869-879

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] Akt signaling promotes derivation of embryonic germ cells from primordial germ cells2008

    • Author(s)
      Kimura, T・Tomooka, M・Yamano, N, 3名, Kanai, Y・Nakano, T
    • Journal Title

      Development (In press)

    • NAID

      120004837399

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] AKT signaling promotes derivation of embryonic germ cells form primordial germ cells.2008

    • Author(s)
      Kimura, et al.
    • Journal Title

      Development 135

      Pages: 2705-2711

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] PGC7/Stella protects against DNA demethylation in early embryogenesis2007

    • Author(s)
      Nakamura T, Arai Y, Umehara H, Masuhara M, Kimura T, Taniguchi H, Sekimoto T, Ikawa M, Yoneda Y, Okabe M, Tanaka S, Shiota K, and Nakano T.
    • Journal Title

      Nature Cell Biol 9(1)

      Pages: 64-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] Efficient derivation of embryonic stem cells by inhibition of glycogen synthasekinase-32007

    • Author(s)
      Umehara, H・Kimura, T・Ohtsuka, S, 4名, Niwa, H・Nakano, T
    • Journal Title

      Stem Cells 25

      Pages: 2705-2711

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Akt mediates self-renewal division of mouse spermatogonial stem cells2007

    • Author(s)
      Lee J, Shinohara-Kanatsu M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Kimura T, Nakano T, Ogura A, and Shinohara T.
    • Journal Title

      Development 134(10)

      Pages: 1853-1859

    • NAID

      120004837569

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] Akt activation induces epidermal hyperplasia and proliferation epidermal progenitors2007

    • Author(s)
      Murayama, K・Kimura, T・Tarutani, M, 5名, Katayama, I・Nakano, T
    • Journal Title

      Oncogene 26

      Pages: 4882-4888

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase 32007

    • Author(s)
      Umehara H, Kimura T, Ohtsuka S, Nakamura T, Kitajima K, Ikawa M, Okabe M, Niwa H, and Nakano T.
    • Journal Title

      Stem Cells 25(11)

      Pages: 2705-2711

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors2007

    • Author(s)
      Murayama K, Kimura T, Tarutani M, Tomooka M, Hayashi R, Okabe M, Nishida K, Itami S, Katayama I, and Nakano T.
    • Journal Title

      Oncogene 26(33)

      Pages: 4882-4888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] AKT signaling promotes derivation of embryonic germ cells form primordial germ cells.2007

    • Author(s)
      Kimura, et. al.
    • Journal Title

      Development 135

      Pages: 869-879

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Journal Article] Differential Effects of GATA-1 on Proliferation and Differentiation of Erythroid Lineage Cells2006

    • Author(s)
      Zheng J, Kitajima J, Sakai E, Kimura T, Minegishi N, Yamamoto M, Nakano T
    • Journal Title

      Blood 107

      Pages: 520-527

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Activation of Akt Signaling is Sufficient to Maintain Pluripotency in Mouse and Primate Embryonic Stem Cells2006

    • Author(s)
      Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T
    • Journal Title

      Oncogene 25

      Pages: 2697-2707

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Differential Effects of GATA-1 on Proliferation and Differentiation of Erythroid Lineage Cells2006

    • Author(s)
      Zheng J, Kitajima K, Sakai E, Kimura T, Minegishi N, Yamamoto M, Nakano T
    • Journal Title

      Blood 107

      Pages: 520-527

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Stabilization of β-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression.2006

    • Author(s)
      Kimura et al.
    • Journal Title

      Dev.Biol. 300 (1)

      Pages: 545-553

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590344
  • [Journal Article] Stabilization of β-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression.2006

    • Author(s)
      Kimura et al.
    • Journal Title

      Dev. Biol. 300巻・1号

      Pages: 545-553

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590344
  • [Journal Article] mili, a mammalian member of piwi family gene, is essential for spermatogenesis2004

    • Author(s)
      Kuramochi-Miyagawa K, Kimura T, (10 authors), Nakano T
    • Journal Title

      Development 131

      Pages: 839-849

    • NAID

      120004837540

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Journal Article] Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.2004

    • Author(s)
      Kuramochi-Miyagawa S, Kimura T, Ijiri T, Asada N, Fujita Y, Ikawa M, Isobe T, Iwai N, Okabe M, Deng W, Lin H, Matsuda Y, Nakano T.
    • Journal Title

      Development 131

      Pages: 839-849

    • NAID

      120004837540

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Stage-specific expression of mouse germ cell-less-1 (mGCL-1) and multiple deformation during mgcl-1 deficient spermatogenesis leading to reduced fertility.2004

    • Author(s)
      Maekawa M, Ito C, Toyama Y, Suzuki-Toyota F, Kimura T, Nakano T, Toshimori K.
    • Journal Title

      Arch.Histol.Cytol. 67

      Pages: 335-347

    • NAID

      10014259520

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003

    • Author(s)
      Kimura, T.
    • Journal Title

      Development 130(8)

      Pages: 1691-1700

    • NAID

      120004837477

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380381
  • [Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003

    • Author(s)
      Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T.
    • Journal Title

      Development 130

      Pages: 1691-1700

    • NAID

      120004837477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Mouse germ cell-less as an essential component for nuclear integrity.2003

    • Author(s)
      Kimura T.Ito C, Watanabe S, Takahashi T, Ikawa M, Yomogida K, Fujita Y, Ikeuchi M, Asada N, Matsumiya K, Okuyama A, Okabe M, Toshimori K, Nakano T.
    • Journal Title

      Mol.Cell.Biol. 23

      Pages: 1304-1315

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Mouse germ cell-less as an essential component for nuclear integrity2003

    • Author(s)
      Kimura, T., et al.
    • Journal Title

      Mol.Cell.Biol. 23(4)

      Pages: 1304-1315

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380381
  • [Journal Article] Cadherin-mediated cell interaction regulate germ cell determination in mice.2003

    • Author(s)
      Okamura D, Kimura T, Nakano T, Matsui Y.
    • Journal Title

      Development 130

      Pages: 6423-6430

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003

    • Author(s)
      Kimura et al.
    • Journal Title

      Development 130,8

      Pages: 1691-1700

    • NAID

      120004837477

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003

    • Author(s)
      Kimura, T., et al.
    • Journal Title

      Development 130(8)

      Pages: 1691-1700

    • NAID

      120004837477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380381
  • [Journal Article] Mouse germ cell-less as an essential component for nuclear integrity.2003

    • Author(s)
      Kimura, T.
    • Journal Title

      Mol. Cell. Biol. 23(4)

      Pages: 1304-1315

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380381
  • [Journal Article] Mouse germ cell-less as an essential component for nuclear integrity.2003

    • Author(s)
      Kimura et al.
    • Journal Title

      Mol.Cell.Biol. 23,4

      Pages: 1304-1315

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.2003

    • Author(s)
      Masuhara M, Nagao K, Nishikawa M, Kimura T, Nakano T.
    • Journal Title

      Biochem.Biophys.Res.Commun. 308

      Pages: 927-932

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590343
  • [Journal Article] Activation of Akt Signaling is Sufficient to Maintain Pluripotency in Mouse and Primate Embryonic Stem Cells

    • Author(s)
      Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T
    • Journal Title

      Oncogene 2006(In press)

    • Data Source
      KAKENHI-PROJECT-15080206
  • [Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.2023

    • Author(s)
      Yoichi Sekita, Shin Kojima, Naoya Shiochi, Tohru Kimura
    • Organizer
      Genomic Imprinting, from Biology to Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.2023

    • Author(s)
      Yoichi Sekita, Shin Kojima, Naoya Shiochi, Tohru Kimura
    • Organizer
      The 21st Takeda Science Foundation Symposium on Bioscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2023

    • Author(s)
      Sekita Y, Kojima S, Shiochi N, Kimura T
    • Organizer
      第21回武田科学振興財団生命科学シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2023

    • Author(s)
      Sekita Y, Kojima S, Shiochi N, Kimura T
    • Organizer
      Genomic Imprinting from Biology to Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] STELLAによるZFP57の制御機構の解析2022

    • Author(s)
      御園杏里、山崎瑛司、中村肇伸、木村透、関田洋一
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] Nlrp5及びNlrp9の雌マウスの生殖能における役割2022

    • Author(s)
      横田佳奈、田村史織、永田圭、神崎理子、 関田洋一、木村透
    • Organizer
      第45回分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] レクチンマイクロアレイを用いたマウス心臓糖鎖における局在と加齢変化2022

    • Author(s)
      板倉陽子、吉川友里香、杉浦功祐、岡谷(永井)千晶、佐々木紀彦、木村透、久野敦、豊田雅士
    • Organizer
      第41回 日本糖質学会
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] 染色体がコードするヒストン脱メチル化酵素KDM5CとKDM5Dのマウス胚発生における機能的差異と相同性2022

    • Author(s)
      永田圭、小杉真由子、大谷舞衣、池田優美、吉川友里香、板倉陽子、豊田雅士、関田洋一、木村透
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] Nlrp5およびNlrp9の雌マウスの生殖能における役割2022

    • Author(s)
      横田佳奈、田村史織、永田圭、神﨑理子、伊藤駿瑛、若林美月、関田洋一、木村透
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] 性染色体がコードするヒストン脱メチル化酵素KDM5CとKDM5Dのマウス胚発生における機能的差異と相同性2022

    • Author(s)
      永田圭、小杉真由子、大谷舞衣、池田優美、吉川友里香、板倉陽子、豊田雅士、関田洋一、木村透
    • Organizer
      第45回分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] STELLAによるZFP57の制御機構の解析2022

    • Author(s)
      御園杏里、山﨑瑛司、中村肇伸、木村透、関田洋一
    • Organizer
      第45回分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] SWI/SNFクロマチンリモデリング複合体による生殖細胞の性分化開始機構2022

    • Author(s)
      太田昌美、伊藤駿瑛、長田純輝、 西山晃、石黒啓一郎、田村智彦、関田洋一、木村透
    • Organizer
      第45回分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] SWI/SNFクロマチンリモデリング複合体による生殖細胞の性分化開始機構の解明2022

    • Author(s)
      太田昌美、伊藤駿瑛、長田純輝、西山晃、石黒啓一郎、田村智彦、関田洋一、木村透
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] エピゲノム編集によるDlk1-Dio3インプリントドメインでのDNAメチル化の機能解析2022

    • Author(s)
      関田洋一、児島進、塩地直弥、小林慎、木村透
    • Organizer
      第15回 エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-22K06046
  • [Presentation] SWI/SNFクロマチンリモデリング複合体による始原生殖細胞の性分化制御機構2020

    • Author(s)
      長田純輝、伊藤駿瑛、西山晃、田村智彦、関田洋一、木村透
    • Organizer
      第43回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] DNA脱メチル化ツールを用いたIG-DMRにおけるDNAメチル化の機能解析2020

    • Author(s)
      児島進、塩地直弥、木村透、関田洋一
    • Organizer
      第43回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K07577
  • [Presentation] PTEN Plays Multiple Roles by Regulating Both PI3K/Akt and MEK/Erk Signaling Pathway During the Mammalian Inner Ear Development2013

    • Author(s)
      Murata J, Sakuraba M, Kimura T, Suzuki A, Mak T, Okano H, Nakano T, Ikeda K
    • Organizer
      The 36th Annual Midwinter Meeting of ARO
    • Place of Presentation
      Baltimore Marriott Waterfront Hotel, Baltimore, Maryland)
    • Data Source
      KAKENHI-PROJECT-23592496
  • [Presentation] PTEN Plays Multiple Roles by Regulating Both PI3K/Akt and MEK/Erk Signaling Pathway During the Mammalian Inner Ear Development2013

    • Author(s)
      Junko Murata, Mayumi Sakuraba, Tohru Kimura, Akira Suzuki, Tak Mak, Hideyuki Okano, Toru Nakano, Katsuhisa Ikeda
    • Organizer
      The 36th Annual Midwinter Meeting of the Association for Research in Otolaryngology
    • Place of Presentation
      Baltimore Marriott Waterfront Hotel, Baltimore, Maryland
    • Data Source
      KAKENHI-PROJECT-23592496
  • [Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by manipulation of signaling pathways2011

    • Author(s)
      Kimura T, Saitou M, Shinohara T, and Nakano T
    • Organizer
      The 9th Stem Cell Research Symposium
    • Place of Presentation
      東京都泉ガーデンギャラリー
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by manipulation of signaling pathways2011

    • Author(s)
      木村透
    • Organizer
      The 9^<th> Stem Cell Research Symposium
    • Place of Presentation
      泉ガーデンギャラリー(東京都)
    • Year and Date
      2011-05-13
    • Data Source
      KAKENHI-PUBLICLY-23125508
  • [Presentation] リン酸化シグナルによる生殖細胞と多能性幹細胞の相互転換2011

    • Author(s)
      木村透
    • Organizer
      第12回長崎障害者支援再生医療研究会
    • Place of Presentation
      長崎大学(長崎県)(招待講演)
    • Year and Date
      2011-08-02
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] 多能性幹細胞と始原生殖細胞の相互転換機構2011

    • Author(s)
      木村透
    • Organizer
      第10回日本再生医療学会
    • Place of Presentation
      京王プラザホテル(招待講演)
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] リン酸化シグナルによる生殖細胞と多能性幹細胞の相互転換2011

    • Author(s)
      木村透
    • Organizer
      第12回長崎障害者支援再生医療研究会
    • Place of Presentation
      長崎大学
    • Year and Date
      2011-08-02
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by manipulation of signaling pathways2011

    • Author(s)
      木村透
    • Organizer
      The 9^<th> Stem Cell Research Symposium
    • Place of Presentation
      泉ガーデンギャラリー(東京都)
    • Year and Date
      2011-05-13
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] リン酸化シグナルによる生殖細胞と多能性幹細胞の相互転換2011

    • Author(s)
      木村透
    • Organizer
      第12回長崎障害者支援再生医療研究会
    • Place of Presentation
      長崎大学(長崎県)(招待講演)
    • Year and Date
      2011-08-02
    • Data Source
      KAKENHI-PUBLICLY-23125508
  • [Presentation] 多能性幹細胞と始原生殖細胞の相互転換機構2011

    • Author(s)
      木村透、李坤鵬、山野範子、仲野徹
    • Organizer
      第10回日本再生医療学会シンポジウム「iPS・ES細胞の万能性と維持機構の解明~PluriPCtencyの正体とは~」
    • Place of Presentation
      京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] Metastable primordial germ cell-like stata induced from mouse embryonic stem cells by Akt activation2010

    • Author(s)
      Kimura. T, Yamano.N, Shinohara T, and Nakano T
    • Organizer
      The 8^<th> Stem Cell Researeh Sympogium
    • Place of Presentation
      淡路夢舞台国際会議場
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.2010

    • Author(s)
      Kimura T.
    • Organizer
      第8回 幹細胞シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] piRNA生合成におけるMVHの役割2010

    • Author(s)
      宮川-倉持さとみ、渡部聡朗、高松加奈、中馬新一郎、後藤健吾、小島-北加奈子、城本悠助、伊藤大介、木村透、野瀬俊明、佐々木裕之、仲野徹
    • Organizer
      第12回日本RBA学会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20610002
  • [Presentation] Induction of the primordial germ cell-like states from mouse embryonic stem cells by manipulation of signaling pathways.2010

    • Author(s)
      Kimura T, Yamano N, Li K-P, Sai tou M, Shinohara T, and Nakano T
    • Organizer
      特定領域研究「生殖系列の世代サイクルとエピゲノムネットワーク」による国際シンポジウムInternational symposium on" Epigenome Network, Developmenta. and Reprogramming of Germ Cells"
    • Place of Presentation
      九州大学
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] Induction of the primordial germ cell-like states from mouse embryonic stem cells by manipulation of signaling pathways.2010

    • Author(s)
      Kimura T.
    • Organizer
      International symposium on "Epigenome Network, Development and Reprogramming of Germ Cells"
    • Place of Presentation
      九州大学 医学部100年講堂
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] small RNAs and gene silencing in spermatogenesis2009

    • Author(s)
      宮川(倉持)さとみ、後藤健吾、小島加奈子、高松可奈、勝俣明子、城本悠助、浅田徳子、木村透、野瀬俊明、仲野徹
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-20610002
  • [Presentation] An Akt-signal dependent metastable pluripotency state showing primordial germ cell-like gene expression2009

    • Author(s)
      Kimura. T, Yamano N, and Nakano T
    • Organizer
      Cold Spring Harbor Symposium Stem Cell Biology Meeting
    • Place of Presentation
      Cold Spring Harbor Laboratory, USA
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] PI3K/ Aktシグナルによる生殖細胞分化と幹細胞システムの制御2009

    • Author(s)
      木村透
    • Organizer
      国立成育医療センター研究所セミナー
    • Place of Presentation
      国立成育医療センター研究所
    • Year and Date
      2009-09-04
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] An Akt-signal dependent metastable pluripotency stare showing primordial germ cell-like gene expression.2009

    • Author(s)
      木村透
    • Organizer
      Cold Spring Harbor Symposium
    • Place of Presentation
      Cold Spring Harbor Lab (NY, USA)
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] マウス始原生殖細胞とその幹細胞性の制御2009

    • Author(s)
      木村透
    • Organizer
      日本受精着床学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] マウス始原生殖細胞とその幹細胞性の制御2009

    • Author(s)
      木村透、山野範子、仲野徹
    • Organizer
      第27回日本受精着床学会総会・学術講演会シンポジウム「生殖医療におけるstem cell biologyとその可能性」
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-21390119
  • [Presentation] 分化多能性の獲得と維持におけるPI3K/Aktシグナルの機能2008

    • Author(s)
      木村透、中村肇伸、山野範子、鈴木聡、仲野徹
    • Organizer
      第6回幹細胞シンポジウム
    • Place of Presentation
      学術総合センター
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] PI3K/Aktシグナルによる多能性幹細胞システムの制御2008

    • Author(s)
      木村透、中村肇伸、山野範子、山本敏之、鈴木聡、仲野徹
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会合同学会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] Regulation of Pluripotency in Mouse Primordial Germ Cells2008

    • Author(s)
      Kimura T, Yamano N, Yamamoto T, and Nakano T.
    • Organizer
      Cold Spring Harbor Symposium Germ Cell Meeting
    • Place of Presentation
      Cold Spring Harbor Laboratory
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] PI3K/Aktシグナルによる多能性幹細胞システムの制御2008

    • Author(s)
      木村 透
    • Organizer
      第31回 曰本分子生物学会年会 第81回日本生化学会合同学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] PI3K-Aktシグナルによる幹細胞システム制御2007

    • Author(s)
      木村透、鈴木聡、仲野徹
    • Organizer
      第40回日本発生生物学会、第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] Aktシグナルによる表皮幹細胞の活性化と前駆細胞の増幅2007

    • Author(s)
      木村透、村山一茂、樽谷勝仁、林竜平、岡部勝、板見智、片山一朗、仲野徹
    • Organizer
      第5回幹細胞シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] PI3K-Aktシグナルによる幹細胞システム制御2007

    • Author(s)
      木村 透
    • Organizer
      第40回日本発生生物学会、第59回日本細胞生物学会 合同大会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2007-05-30
    • Data Source
      KAKENHI-PROJECT-19390113
  • [Presentation] Promotion of iPS cell induction by Akt signaling activation.

    • Author(s)
      Fujikawa K & Kimura T
    • Organizer
      The 12th Stem Cell Research Symposium
    • Place of Presentation
      九州大学
    • Year and Date
      2014-05-29 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-24390097
  • [Presentation] 始原生殖細胞の分化と脱分化

    • Author(s)
      木村 透
    • Organizer
      京都大学霊長類研究所研究会 「霊長類への展開に向けた幹細胞・生殖細胞・エピゲノム研究」
    • Place of Presentation
      京都大学
    • Year and Date
      2014-08-26 – 2014-08-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390097
  • [Presentation] Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds.

    • Author(s)
      Kimura T et al.
    • Organizer
      The 12th Stem Cell Research Symposium
    • Place of Presentation
      九州大学
    • Year and Date
      2014-05-29 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-24390097
  • [Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by ERK signal inhibition.

    • Author(s)
      Odamoto M & Kimura T et al.
    • Organizer
      The 12th Stem Cell Research Symposium
    • Place of Presentation
      九州大学
    • Year and Date
      2014-05-29 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-24390097
  • 1.  NAKANO Toru (00172370)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 15 results
  • 2.  NADA Shigeyuki (50291448)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  TARUTANI Masahito (30301261)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  IKAWA Masahito (20304066)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  Sekita Yoichi (20431950)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 6.  鈴木 聡 (10311565)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KITAJIMA Kenji (10346132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  MIYAGAWA Satomi (90291153)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MURATA junko (80332740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  SHINOHARA Takashi (30322770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NOGUCHI Motoko (40021951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TOKUMOTO Toshinobu (30273163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NOZAKI Masami (30189394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  岡部 勝 (30089875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  松本 俊英 (10623184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OSAWA Masaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MATSUMOTO Kayoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  大沢 匡毅
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ISOTANI Ayako
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  ITAKURA Yoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  SATO Koji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  NAKAMURA Toshinobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  西山 晃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  倉持 敏美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 25.  岡田 雅人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  太田 安隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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