Kimura Toru 木村透

… Alternative Names

KIMURA Tohru 木村透

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Researcher Number	50280962
Other IDs
External Links
Affiliation (Current)	2025: 北里大学, 理学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 北里大学, 理学部, 教授 2012 – 2014: 北里大学, 理学部, 教授 2010 – 2012: 大阪大学, 生命機能研究科, 准教授 2010: 大阪大学, 大学院・生命機能研究科, 准教授 2007 – 2009: Osaka University, 医学系研究科, 准教授 … More 2008: Osaka University, 医学系・研究科, 准教授 2004 – 2006: 大阪大学, 医学系研究科, 助教授 2004: Osaka University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2001 – 2004: 大阪大学, 微生物病研究所, 助教授 1999 – 2000: 大阪大学, 微生物病研究所, 助手 1996 – 1998: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Experimental pathology / Virology / Basic Section 42030:Animal life science-related / Biological Sciences Except Principal Investigator General medical chemistry / Basic Section 43050:Genome biology-related / Basic Section 50010:Tumor biology-related / Laboratory animal science / Hematology … More / Otorhinolaryngology / Cell biology / Stem cell biology and medical science / Biological Sciences / Pathological medical chemistry Less
Keywords	Principal Investigator 始原生殖細胞 / ES細胞 / 幹細胞 / 生殖細胞 / PI3K / Wnt / EG細胞 / 幹細胞システム / PTEN / 生殖系列 … More / Aktシグナル / Akt signal / β-catenin signal / ES cell / β-cateninシグナル / germ cell-less / primordial germ cells / Cre / EGFP / Oct-3 / coiled-coil / AIDS / HIV / 減数分裂 / iPS細胞 / 多能性 / 初期化 / 胚性幹細胞 / シグナル伝達 / 転写因子 / SWI/SNF複合体 / クロマチンリモデリング / de novo DNAメチル化 / 性分化 / 配偶子形成 / 有性生殖 / stem cell system / EG cell / primordial germ ce;; / 発癌 / 表皮幹細胞 / stem cell / germ cell / primordial germ cell / P13キナーゼ / tumor suppressor / stem cells / pluripotency / EG cells / クロマチン・リモデリング / germ cell-less遺伝子 / 胚性生殖細胞 / テラトーマ / Pten遺伝子 / 精子形態形成 / 癌抑制遺伝子 / 分化全能性 / loxP system / transgenic mice / 4 gene / TNAP gene / Germ lineage / germ cell-less(gcl)遺伝子 / 生殖質 / loxP系 / loxPシステム / トランスジェニックマウス / 4遺伝子 / TNAP遺伝子 / protein trafficking / Nafl (Nef-associated factor 1) / CD4 downregulation / 活性化T細胞 / Nef結合因子 / SH3ドメイン / Naf1(Nef-associated factor1) / タンパク輸送 / Naf1(Nef-associated factor 1) / Nef / 相互転換 / シグナル / 分化誘導 / 精子形成 / レトロトランスポゾン / PIWIファミリー / マウス / PIWI / 小分子RNA / piRNA / 対合 / 相同染色体 / DNAメチル化 / 分化可塑性 / 中胚葉分化 / 中胚葉誘導 / 胚性幹細胞(ES細胞) / ERKシグナル / 再生医学 / リン酸化シグナル / 生殖幹細胞 / 毛包幹細胞 / 上皮幹細胞 / GSK3β / 間葉系幹細胞 / 軟骨 / Akt / 脱分化 / 組織幹細胞 / リン酸化酵素 / インターフェロン / ISGF3 / p48 / IRF-1 / 転写制御 / 感染 / ウイルス … More Except Principal Investigator PTEN / 幹細胞 / 細胞分化 / 精子形成 / DNAメチル化 / 始原生殖細胞 / エピゲノム / エピジェネティクス / GATA-2 / 転写因子 / 胚性幹細胞 / 胚性生殖細胞 / 脱分化 / 生殖細胞 / レトロトランスポゾン / エピゲノム編集 / ゲノムインプリンティング / 代謝産物 / state transition / グリオブラストーマ / 膠芽腫 / AKTシグナル / がん幹細胞 / Totipotency / Primordial germ cells / Chromosome mapping / Teratoma candidate / KO mouse / Testicular teratomas / Mouse / 精巣性奇形腫(テラトーマ) / 生殖細胞増殖 / 生殖細胞特異遺伝子 / マッピング / 奇形腫(テラトーマ) / 分化全能性 / 染色体マッピング / 奇形腫原因遺伝子 / 遺伝子改変マウス / 奇形腫高発系 / マウス / megakaryocyte / erythrocyte / macrophage / embryonic stem cell / transcription factor / hematopoiesis / stem cell / cell differentiation / 転写調節 / 巨核球 / 赤血球 / マクロファージ / 造血システム / Stroma Cell / Gene Regulation / Transcription Factor / Cell Differentiation / Embryonic Stem Cell / Hematopoiesis / Myb転写因子 / GATA転写因子 / 造血 / 分化誘導 / 造血幹細胞 / Oogenesis / Germ cell-less / Embryonic germ cell / Teratoma / Spermatogenesis / Primordial germ cell / 遺伝子破壊 / 奇形腫 / がん抑制遺伝子 / 生殖系列 / 遺伝子ターゲティング / PI3/Aktシグナル伝達系 / convergent extension / PTEN cko マウス / PI3K/Aktシグナル経路 / 蝸牛 / PI3K/Aktシグナル径路 / 有毛細胞 / 感覚上皮予定領域 / 内耳発生 / ほ乳類 / PTEN ckoマウス / Pi3K/Aktシグナル伝達系 / 細胞内情報伝達 / メンブレントラフィック / リソソーム / 非コードRNA / GS細胞 / IAP / 生殖幹細胞 / piRNA / 小分子RNA / germ cell less / 遺伝子ターゲティングマウス / RNAi / mili / 遺伝子操作 / シグナル伝達 / 細胞文化 / インプリンティング / small RNA / インプリンディング / 初期胚 / 遺伝子発現制御 / エピジェネヒィック制御 / germ cell-less(gcl) / Cre / TAT融合タンパク / protein transduction Less

Exploration and Analysis of Epigenome Control Core Using DNA Methylation Editing Technology
- Principal Investigator
  
  関田洋一
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Kitasato University
雌雄の生殖細胞の性分化を推進させるクロマチンリモデリング複合体の解析Principal Investigator
- Principal Investigator
  
  木村透
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Kitasato University
Elucidation of epigenomic and metabolic control by Akt signaling in the development of cancer stem cells
- Principal Investigator
  
  Sekita Yoichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kitasato University
Reciprocal conversion between germ cells and pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kitasato University
マウスＰＩＷＩファミリーによる減数分裂期の染色体構造の制御Principal Investigator
- Principal Investigator
  
  木村透
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
  Osaka University
Regulation of cellular function by late endosomal kinase signaling
- Principal Investigator
  
  NADA Shigeyuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
Functional analysis of the PI3K/Akt signaling pathway during the mammalian inner ear development and its application for regenerative medicine
- Principal Investigator
  
  MURATA junko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Analysis of phosphoryl at ionsignals in regulation of stem cell systemPrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
Analysis of germ stem cells and small RNAs
- Principal Investigator
  
  MIYAGAWA Satomi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Stem cell biology and medical science
- Research Institution
  Osaka University
Roles of phosphorylation signals in regulation of stem cell systemsPrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
Mechanisms regulating mouse germline establishment and stem cell systemsPrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
生殖細胞の成立と分化における分子基盤
- Principal Investigator
  
  仲野徹
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis of mouse primordial germ cell development and stem cell systemsPrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
MOLECULAR BASIS OF STEM CELL SYSTEMS AND ITS APPLICATION
- Principal Investigator
  
  NAKANO Toru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  OSAKA UNIVERSITY
GENETIC AND DEVELOPMENTAL ANALYSIS OF MECHANISMS UNDERLYING TERATOCARCINOGENESIS IN THE MOUSE GERM CELLS.
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shizuoka University
Analysis of molecules involved in mouse primordial germ cell developmentPrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
タンパク導入法を用いた遺伝子欠損の実験的治療
- Principal Investigator
  
  NAKANO Toru
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Molecular Mechanisms for Maintaining Stem Cell Immaturity
- Principal Investigator
  
  NAKANO Toru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Manipulation of hematopoietic cells for regenerative medicine
- Principal Investigator
  
  NAKANO Toru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Analysis of molecules involved in mouse primordial germ cell development using transgenic micePrincipal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
Structural and Functional Analysis of Nef Protein of Human Immunodeficiency Virus (HIV)Principal Investigator
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University
ウイルス感染による免疫応答異常における、転写制御及びシグナル伝達機構の異常の解析Principal Investigator
- Principal Investigator
  
  木村透
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University

[Book] Regulatory Networks in Stem Cells2009
- Author(s)
  Kimura, Nakano
- Publisher
  Humana/Springer Press(in press)
- Data Source
  KAKENHI-PROJECT-19390113
[Book] Regulation of stem cell systems by PI3K/Akt signaling2009
- Author(s)
  Kimura T, and Nakano T.
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-19390113
[Book] Regulatory Networks in Stem Cells2009
- Author(s)
  Kimura, Nakano
- Total Pages
  9
- Publisher
  Humana/Springer
- Data Source
  KAKENHI-PROJECT-21390119
[Book] Testicular Teratomas: Back to Pluripotent Stem Cells in Developmental Biology of Neoplastic Growth2005
- Author(s)
  Kimura T, Murayama K, Nakamura T, Watanabe S, Umehara H, Tomooka M, Nakano T
- Total Pages
  15
- Publisher
  Springer, Berlin
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Human intestinal organoid-derived PDGFRα?+?mesenchymal stroma enables proliferation and maintenance of LGR4?+?epithelial stem cells2024
- Author(s)
  Chen JunLong、Horiuchi Shinichiro、Kuramochi So、Kawasaki Tomoyuki、Kawasumi Hayato、Akiyama Saeko、Arai Tomoki、Morinaga Kenichi、Kimura Tohru、Kiyono Tohru、Akutsu Hidenori、Ishida Seiichi、Umezawa Akihiro
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 15 Issue: 1 Pages: 16-16
- DOI
  10.1186/s13287-023-03629-5
- Data Source
  KAKENHI-PROJECT-22K06046
[Journal Article] Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells2023
- Author(s)
  Akiyama Saeko、Saku Noriaki、Miyata Shoko、Ite Kenta、Nonaka Hidenori、Toyoda Masashi、Kamiya Akihide、Kiyono Tohru、Kimura Tohru、Kasahara Mureo、Umezawa Akihiro
- Journal Title
  
  Progress in Molecular Biology and Translational Science
  
  Volume: 199 Pages: 155-178
- DOI
  10.1016/bs.pmbts.2023.02.009
- ISBN
  9780443134111
- Data Source
  KAKENHI-PROJECT-22K06046
[Journal Article] Genetic variation in the Y chromosome and sex-biased DNA methylation in somatic cells in the mouse.2023
- Author(s)
  Batdorj E, AlOgayil N, Galvez JH, Zhuang QK, Bauermeister K, Nagata K, Kimura T, Ward M, Taketo T, Bourque G, and Naumova AK
- Journal Title
  
  Mammalian Genome
  
  Volume: 34 Issue: 1 Pages: 44-55
- DOI
  10.1007/s00335-022-09970-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06046
[Journal Article] Spatiotemporal changes of tissue glycans depending on localization in cardiac aging2023
- Author(s)
  Itakura Yoko、Hasegawa Yasuko、Kikkawa Yurika、Murakami Yuina、Sugiura Kosuke、Nagai-Okatani Chiaki、Sasaki Norihiko、Umemura Mariko、Takahashi Yuji、Kimura Tohru、Kuno Atsushi、Ishiwata Toshiyuki、Toyoda Masashi
- Journal Title
  
  Regenerative Therapy
  
  Volume: 22 Pages: 68-78
- DOI
  10.1016/j.reth.2022.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-22K06046, KAKENHI-PROJECT-20K17136, KAKENHI-PROJECT-21K19754, KAKENHI-PROJECT-22K11794
[Journal Article] Stem cell challenges and opportunities2023
- Author(s)
  Ite Kenta、Toyoda Masashi、Akiyama Saeko、Enosawa Shin、Yoshioka Saeko、Yukitake Takaaki、Yamazaki-Inoue Mayu、Tatsumi Kuniko、Akutsu Hidenori、Nishina Hiroshi、Kimura Toru、Otani Naoko、Nakazawa Atsuko、Fukuda Akinari、Kasahara Mureo、Umezawa Akihiro
- Journal Title
  
  Progress in Molecular Biology and Translational Science
  
  Volume: 199 Pages: 379-395
- DOI
  10.1016/bs.pmbts.2023.03.004
- ISBN
  9780443134111
- Data Source
  KAKENHI-PROJECT-22K06046
[Journal Article] Mechanism of promotion of cell reprogramming by AKT signal2023
- Author(s)
  関田洋一、木村透
- Journal Title
  
  生化学
  
  Volume: 95 Issue: 1 Pages: 66-71
- DOI
  10.14952/SEIKAGAKU.2023.950066
- ISSN
  0037-1017
- Year and Date
  2023-02-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07577
[Journal Article] Switching defective/sucrose non‐fermenting chromatin remodeling complex coordinates meiotic gene activation via promoter remodeling and Meiosin activation in female germline2022
- Author(s)
  Ito Toshiaki、Ohta Masami、Osada Atsuki、Nishiyama Akira、Ishiguro Kei‐Ichiro、Tamura Tomohiko、Sekita Yoichi、Kimura Tohru
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 1 Pages: 15-28
- DOI
  10.1111/gtc.12990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-22K06046, KAKENHI-PROJECT-21H02954
[Journal Article] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2022
- Author(s)
  Kojima Shin、Shiochi Naoya、Sato Kazuki、Yamaura Mamiko、Ito Toshiaki、Yamamura Nodoka、Goto Naoki、Odamoto Mika、Kobayashi Shin、Kimura Tohru、Sekita Yoichi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 9 Pages: 5080-5094
- DOI
  10.1093/nar/gkac344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-22K06046
[Journal Article] A RUNX?CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes2021
- Author(s)
  Murakami Koichi、Sasaki Haruka、Nishiyama Akira、Kurotaki Daisuke、Kawase Wataru、Ban Tatsuma、Nakabayashi Jun、Kanzaki Satoko、Sekita Yoichi、Nakajima Hideaki、Ozato Keiko、Kimura Tohru、Tamura Tomohiko
- Journal Title
  
  Nature Immunology
  
  Volume: 22 Issue: 3 Pages: 301-311
- DOI
  10.1038/s41590-021-00871-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07372, KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-16H06279
[Journal Article] Five multicopy gene family genes expressed during the maternal-to-zygotic transition are not essential for mouse development2021
- Author(s)
  Wakabayashi Mizuki、Tamura Shiori、Kanzaki Satoko、Kosugi Mayuko、Yoshimura Yuki、Ito Toshiaki、Nagata Kei、Sato Kazuha、Takada Shuji、Sekita Yoichi、Kimura Tohru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 752-757
- DOI
  10.1016/j.bbrc.2020.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07577
[Journal Article] AKT signaling is associated with epigenetic reprogramming via the upregulation of TET and its cofactor, alpha-ketoglutarate during iPSC generation2021
- Author(s)
  Sekita Y, Sugiura Y, Matsumoto A, Kawasaki Y, Akasaka K, Konno R, Shimizu M, Ito T, Sugiyama E, Yamazaki T, Kanai E, Nakamura T, Suematsu M, Ishino F, Kodera Y, Kohda T, Kimura T.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: - Issue: 1 Pages: 510-510
- DOI
  10.1186/s13287-021-02578-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05374, KAKENHI-PROJECT-19H00978, KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-20K20584
[Journal Article] SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline2021
- Author(s)
  Ito Toshiaki、Osada Atsuki、Ohta Masami、Yokota Kana、Nishiyama Akira、Niikura Yuichi、Tamura Tomohiko、Sekita Yoichi、Kimura Tohru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 24074-24074
- DOI
  10.1038/s41598-021-03538-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07577
[Journal Article] Involvement of Nlrp9a/b/c in mouse preimplantation development2020
- Author(s)
  Kanzaki Satoko, Tamura Shiori, Ito Toshiaki, Wakabayashi Mizuki, Saito Koji, Kato Shigeki, Ohta Yasutaka, Sekita Yoichi, Kimura Tohru
- Journal Title
  
  Reproduction
  
  Volume: 160 Issue: 2 Pages: 181-191
- DOI
  10.1530/rep-19-0516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06227, KAKENHI-PROJECT-20K07577
[Journal Article] Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds.2015
- Author(s)
  Kimura T et al.
- Journal Title
  
  Stem Cells
  
  Volume: 33 Issue: 1 Pages: 45-55
- DOI
  10.1002/stem.1838
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390097, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-26112515, KAKENHI-PROJECT-26250025
[Journal Article] Induction of Primordial Germ Cell-Like Cells From Mouse Embryonic Stem Cells by ERK Signal Inhibition.2014
- Author(s)
  Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujikawa K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T.
- Journal Title
  
  Stem Cells
  
  Volume: 32 Issue: 10 Pages: 2668-2678
- DOI
  10.1002/stem.1781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24390097, KAKENHI-PROJECT-24500490, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25293067
[Journal Article] The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase2014
- Author(s)
  Mori S, Nada S, Kimura H, Tajima S, Takahashi Y, Kitamura A, Oneyama C, Okada M.
- Journal Title
  
  PLos ONE
  
  Volume: 9(2) Issue: 2 Pages: e88891-e88891
- DOI
  10.1371/journal.pone.0088891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22240088, KAKENHI-PROJECT-23370087, KAKENHI-PUBLICLY-24116515, KAKENHI-PROJECT-24659150, KAKENHI-PUBLICLY-25117716, KAKENHI-PROJECT-25650007, KAKENHI-PROJECT-26640078
[Journal Article] Induction of pluripotency in primordial germ cells.2011
- Author(s)
  Kimura, et al.
- Journal Title
  
  Histol.Histopatho.
  
  Volume: (印刷中)
- NAID
  40019072189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of Tffrogulatory factor 2(Trf2) in trypsinogen5 gene transcription2011
- Author(s)
  Hayashi H, Kohno T, Yasui K, Murota H, Kimura T, Duncan GS, Nakashima T, Yamamoto K, Katayama. I, Ma. Y, Chua. KJ, Suematsu T, himokawa T, Akira S, Kubo Mak TW, and Matsuyama. T
- Journal Title
  
  Proc. Natl. Acad. Sci, USA
  
  Volume: 108(46) Pages: 18766-18771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] Induction of pluripotency in primordial germ cells2011
- Author(s)
  Kimura. T, and Nakano T
- Journal Title
  
  Histol. Histopatho
  
  Volume: 26(5) Pages: 643-650
- NAID
  40019072189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] Induction of pluripotency in primordial germ cells2011
- Author(s)
  Kimura, et al.
- Journal Title
  
  Histol.Histopatho.
  
  Volume: 26 Pages: 643-650
- NAID
  40019072189
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23125508
[Journal Article] Induction of pluripotency in primordial germ cells2011
- Author(s)
  Kimura, et al
- Journal Title
  
  Histol.Histopatho.
  
  Volume: 26 Pages: 643-650
- NAID
  40019072189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] MVH in piRNA processing and gene silencing of retrotransposons2010
- Author(s)
  Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Kimura T, Nakatsuji N, Noce T, Sasaki H, and Nakano T
- Journal Title
  
  Genes Dev
  
  Volume: 24(9) Pages: 887-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] MVH in piRNA Processing and Gene Silencing of Retrotransposons2010
- Author(s)
  Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T.
- Journal Title
  
  Genes Dev. 23
  
  Pages: 887-892
- Data Source
  KAKENHI-PROJECT-20610002
[Journal Article] Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation2010
- Author(s)
  Yamano N, Kimura. T, Watanabe-Kushima S, Shinohara. T, and Nakano T
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 392(3) Pages: 311-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] Associations between PIWI Proteins and TDRD1/ MTR-1 are critical for integrated subcellular localization in murine male germ cells2009
- Author(s)
  Kojima K, Kuramochi-Miyagawa S, Chuma S, Tanaka T, Nakatsuji N, Kimura T, and Nakano T
- Journal Title
  
  Genes Cells
  
  Volume: 14(10) Pages: 1155-1165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390119
[Journal Article] Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.2009
- Author(s)
  Kojima K.Kuramochi-Miyagawa S.Chuma S.Tanaka T.Nakatsuji N.Kimura T.Nakano T.
- Journal Title
  
  Genes to Cells. 14(10)
  
  Pages: 1155-1165
- Data Source
  KAKENHI-PROJECT-20610002
[Journal Article] PI3K/Akt signaling as a key regulatory pathway for chondrocyte terminal differentiation2008
- Author(s)
  Kita K, Kimura T, Nakamura N, Yoshikawa H, and Nakano T.
- Journal Title
  
  Genes Cells 13(8)
  
  Pages: 839-850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes2008
- Author(s)
  Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M , Asada N, Kojima K, Yamaguchi Y, Ijiri T, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, and Nakano T.
- Journal Title
  
  Genes Dev 22(7)
  
  Pages: 908-917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] Effects of Akt signaling on nuclear reprogramming2008
- Author(s)
  Nakamura T, Inoue K, Ogawa S, Umehara H, Ogonuki N, Miki H, Kimura T, Ogura A, and Nakano T.
- Journal Title
  
  Genes Cells 13(12)
  
  Pages: 1269-1277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] AKT signaling promotes derivation of embryonic germ cells form primordial germ cells2008
- Author(s)
  Kimura T, Tomooka M, Yamano N, Murayama K, Matoba S, Umehara H, Kanai Y, and Nakano T.
- Journal Title
  
  Development 135(5)
  
  Pages: 869-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] Akt signaling promotes derivation of embryonic germ cells from primordial germ cells2008
- Author(s)
  Kimura, T・Tomooka, M・Yamano, N, 3名, Kanai, Y・Nakano, T
- Journal Title
  
  Development (In press)
- NAID
  120004837399
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] AKT signaling promotes derivation of embryonic germ cells form primordial germ cells.2008
- Author(s)
  Kimura, et al.
- Journal Title
  
  Development 135
  
  Pages: 2705-2711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] PGC7/Stella protects against DNA demethylation in early embryogenesis2007
- Author(s)
  Nakamura T, Arai Y, Umehara H, Masuhara M, Kimura T, Taniguchi H, Sekimoto T, Ikawa M, Yoneda Y, Okabe M, Tanaka S, Shiota K, and Nakano T.
- Journal Title
  
  Nature Cell Biol 9(1)
  
  Pages: 64-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] Efficient derivation of embryonic stem cells by inhibition of glycogen synthasekinase-32007
- Author(s)
  Umehara, H・Kimura, T・Ohtsuka, S, 4名, Niwa, H・Nakano, T
- Journal Title
  
  Stem Cells 25
  
  Pages: 2705-2711
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Akt mediates self-renewal division of mouse spermatogonial stem cells2007
- Author(s)
  Lee J, Shinohara-Kanatsu M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Kimura T, Nakano T, Ogura A, and Shinohara T.
- Journal Title
  
  Development 134(10)
  
  Pages: 1853-1859
- NAID
  120004837569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] Akt activation induces epidermal hyperplasia and proliferation epidermal progenitors2007
- Author(s)
  Murayama, K・Kimura, T・Tarutani, M, 5名, Katayama, I・Nakano, T
- Journal Title
  
  Oncogene 26
  
  Pages: 4882-4888
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase 32007
- Author(s)
  Umehara H, Kimura T, Ohtsuka S, Nakamura T, Kitajima K, Ikawa M, Okabe M, Niwa H, and Nakano T.
- Journal Title
  
  Stem Cells 25(11)
  
  Pages: 2705-2711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors2007
- Author(s)
  Murayama K, Kimura T, Tarutani M, Tomooka M, Hayashi R, Okabe M, Nishida K, Itami S, Katayama I, and Nakano T.
- Journal Title
  
  Oncogene 26(33)
  
  Pages: 4882-4888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] AKT signaling promotes derivation of embryonic germ cells form primordial germ cells.2007
- Author(s)
  Kimura, et. al.
- Journal Title
  
  Development 135
  
  Pages: 869-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390113
[Journal Article] Differential Effects of GATA-1 on Proliferation and Differentiation of Erythroid Lineage Cells2006
- Author(s)
  Zheng J, Kitajima J, Sakai E, Kimura T, Minegishi N, Yamamoto M, Nakano T
- Journal Title
  
  Blood 107
  
  Pages: 520-527
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Activation of Akt Signaling is Sufficient to Maintain Pluripotency in Mouse and Primate Embryonic Stem Cells2006
- Author(s)
  Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T
- Journal Title
  
  Oncogene 25
  
  Pages: 2697-2707
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Differential Effects of GATA-1 on Proliferation and Differentiation of Erythroid Lineage Cells2006
- Author(s)
  Zheng J, Kitajima K, Sakai E, Kimura T, Minegishi N, Yamamoto M, Nakano T
- Journal Title
  
  Blood 107
  
  Pages: 520-527
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Stabilization of β-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression.2006
- Author(s)
  Kimura et al.
- Journal Title
  
  Dev.Biol. 300 (1)
  
  Pages: 545-553
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590344
[Journal Article] Stabilization of β-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression.2006
- Author(s)
  Kimura et al.
- Journal Title
  
  Dev. Biol. 300巻・1号
  
  Pages: 545-553
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590344
[Journal Article] mili, a mammalian member of piwi family gene, is essential for spermatogenesis2004
- Author(s)
  Kuramochi-Miyagawa K, Kimura T, (10 authors), Nakano T
- Journal Title
  
  Development 131
  
  Pages: 839-849
- NAID
  120004837540
- Data Source
  KAKENHI-PROJECT-15080206
[Journal Article] Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.2004
- Author(s)
  Kuramochi-Miyagawa S, Kimura T, Ijiri T, Asada N, Fujita Y, Ikawa M, Isobe T, Iwai N, Okabe M, Deng W, Lin H, Matsuda Y, Nakano T.
- Journal Title
  
  Development 131
  
  Pages: 839-849
- NAID
  120004837540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Stage-specific expression of mouse germ cell-less-1 (mGCL-1) and multiple deformation during mgcl-1 deficient spermatogenesis leading to reduced fertility.2004
- Author(s)
  Maekawa M, Ito C, Toyama Y, Suzuki-Toyota F, Kimura T, Nakano T, Toshimori K.
- Journal Title
  
  Arch.Histol.Cytol. 67
  
  Pages: 335-347
- NAID
  10014259520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003
- Author(s)
  Kimura, T.
- Journal Title
  
  Development 130(8)
  
  Pages: 1691-1700
- NAID
  120004837477
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380381
[Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003
- Author(s)
  Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T.
- Journal Title
  
  Development 130
  
  Pages: 1691-1700
- NAID
  120004837477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Mouse germ cell-less as an essential component for nuclear integrity.2003
- Author(s)
  Kimura T.Ito C, Watanabe S, Takahashi T, Ikawa M, Yomogida K, Fujita Y, Ikeuchi M, Asada N, Matsumiya K, Okuyama A, Okabe M, Toshimori K, Nakano T.
- Journal Title
  
  Mol.Cell.Biol. 23
  
  Pages: 1304-1315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Mouse germ cell-less as an essential component for nuclear integrity2003
- Author(s)
  Kimura, T., et al.
- Journal Title
  
  Mol.Cell.Biol. 23(4)
  
  Pages: 1304-1315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380381
[Journal Article] Cadherin-mediated cell interaction regulate germ cell determination in mice.2003
- Author(s)
  Okamura D, Kimura T, Nakano T, Matsui Y.
- Journal Title
  
  Development 130
  
  Pages: 6423-6430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003
- Author(s)
  Kimura et al.
- Journal Title
  
  Development 130,8
  
  Pages: 1691-1700
- NAID
  120004837477
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.2003
- Author(s)
  Kimura, T., et al.
- Journal Title
  
  Development 130(8)
  
  Pages: 1691-1700
- NAID
  120004837477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380381
[Journal Article] Mouse germ cell-less as an essential component for nuclear integrity.2003
- Author(s)
  Kimura, T.
- Journal Title
  
  Mol. Cell. Biol. 23(4)
  
  Pages: 1304-1315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380381
[Journal Article] Mouse germ cell-less as an essential component for nuclear integrity.2003
- Author(s)
  Kimura et al.
- Journal Title
  
  Mol.Cell.Biol. 23,4
  
  Pages: 1304-1315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.2003
- Author(s)
  Masuhara M, Nagao K, Nishikawa M, Kimura T, Nakano T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 308
  
  Pages: 927-932
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590343
[Journal Article] Activation of Akt Signaling is Sufficient to Maintain Pluripotency in Mouse and Primate Embryonic Stem Cells
- Author(s)
  Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T
- Journal Title
  
  Oncogene 2006(In press)
- Data Source
  KAKENHI-PROJECT-15080206
[Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.2023
- Author(s)
  Yoichi Sekita, Shin Kojima, Naoya Shiochi, Tohru Kimura
- Organizer
  Genomic Imprinting, from Biology to Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.2023
- Author(s)
  Yoichi Sekita, Shin Kojima, Naoya Shiochi, Tohru Kimura
- Organizer
  The 21st Takeda Science Foundation Symposium on Bioscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2023
- Author(s)
  Sekita Y, Kojima S, Shiochi N, Kimura T
- Organizer
  第21回武田科学振興財団生命科学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2023
- Author(s)
  Sekita Y, Kojima S, Shiochi N, Kimura T
- Organizer
  Genomic Imprinting from Biology to Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] STELLAによるZFP57の制御機構の解析2022
- Author(s)
  御園杏里、山崎瑛司、中村肇伸、木村透、関田洋一
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] Nlrp5及びNlrp9の雌マウスの生殖能における役割2022
- Author(s)
  横田佳奈、田村史織、永田圭、神崎理子、関田洋一、木村透
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] レクチンマイクロアレイを用いたマウス心臓糖鎖における局在と加齢変化2022
- Author(s)
  板倉陽子、吉川友里香、杉浦功祐、岡谷（永井）千晶、佐々木紀彦、木村透、久野敦、豊田雅士
- Organizer
  第41回日本糖質学会
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] 染色体がコードするヒストン脱メチル化酵素KDM5CとKDM5Dのマウス胚発生における機能的差異と相同性2022
- Author(s)
  永田圭、小杉真由子、大谷舞衣、池田優美、吉川友里香、板倉陽子、豊田雅士、関田洋一、木村透
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] Nlrp5およびNlrp9の雌マウスの生殖能における役割2022
- Author(s)
  横田佳奈、田村史織、永田圭、神﨑理子、伊藤駿瑛、若林美月、関田洋一、木村透
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] 性染色体がコードするヒストン脱メチル化酵素KDM5CとKDM5Dのマウス胚発生における機能的差異と相同性2022
- Author(s)
  永田圭、小杉真由子、大谷舞衣、池田優美、吉川友里香、板倉陽子、豊田雅士、関田洋一、木村透
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] STELLAによるZFP57の制御機構の解析2022
- Author(s)
  御園杏里、山﨑瑛司、中村肇伸、木村透、関田洋一
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] SWI/SNFクロマチンリモデリング複合体による生殖細胞の性分化開始機構2022
- Author(s)
  太田昌美、伊藤駿瑛、長田純輝、西山晃、石黒啓一郎、田村智彦、関田洋一、木村透
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] SWI/SNFクロマチンリモデリング複合体による生殖細胞の性分化開始機構の解明2022
- Author(s)
  太田昌美、伊藤駿瑛、長田純輝、西山晃、石黒啓一郎、田村智彦、関田洋一、木村透
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] エピゲノム編集によるDlk1-Dio3インプリントドメインでのDNAメチル化の機能解析2022
- Author(s)
  関田洋一、児島進、塩地直弥、小林慎、木村透
- Organizer
  第15回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-22K06046
[Presentation] SWI/SNFクロマチンリモデリング複合体による始原生殖細胞の性分化制御機構2020
- Author(s)
  長田純輝、伊藤駿瑛、西山晃、田村智彦、関田洋一、木村透
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] DNA脱メチル化ツールを用いたIG-DMRにおけるDNAメチル化の機能解析2020
- Author(s)
  児島進、塩地直弥、木村透、関田洋一
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] PTEN Plays Multiple Roles by Regulating Both PI3K/Akt and MEK/Erk Signaling Pathway During the Mammalian Inner Ear Development2013
- Author(s)
  Murata J, Sakuraba M, Kimura T, Suzuki A, Mak T, Okano H, Nakano T, Ikeda K
- Organizer
  The 36th Annual Midwinter Meeting of ARO
- Place of Presentation
  Baltimore Marriott Waterfront Hotel, Baltimore, Maryland)
- Data Source
  KAKENHI-PROJECT-23592496
[Presentation] PTEN Plays Multiple Roles by Regulating Both PI3K/Akt and MEK/Erk Signaling Pathway During the Mammalian Inner Ear Development2013
- Author(s)
  Junko Murata, Mayumi Sakuraba, Tohru Kimura, Akira Suzuki, Tak Mak, Hideyuki Okano, Toru Nakano, Katsuhisa Ikeda
- Organizer
  The 36th Annual Midwinter Meeting of the Association for Research in Otolaryngology
- Place of Presentation
  Baltimore Marriott Waterfront Hotel, Baltimore, Maryland
- Data Source
  KAKENHI-PROJECT-23592496
[Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by manipulation of signaling pathways2011
- Author(s)
  Kimura T, Saitou M, Shinohara T, and Nakano T
- Organizer
  The 9th Stem Cell Research Symposium
- Place of Presentation
  東京都泉ガーデンギャラリー
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by manipulation of signaling pathways2011
- Author(s)
  木村透
- Organizer
  The 9^<th> Stem Cell Research Symposium
- Place of Presentation
  泉ガーデンギャラリー(東京都)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PUBLICLY-23125508
[Presentation] リン酸化シグナルによる生殖細胞と多能性幹細胞の相互転換2011
- Author(s)
  木村透
- Organizer
  第12回長崎障害者支援再生医療研究会
- Place of Presentation
  長崎大学(長崎県)(招待講演)
- Year and Date
  2011-08-02
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] 多能性幹細胞と始原生殖細胞の相互転換機構2011
- Author(s)
  木村透
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  京王プラザホテル(招待講演)
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] リン酸化シグナルによる生殖細胞と多能性幹細胞の相互転換2011
- Author(s)
  木村透
- Organizer
  第12回長崎障害者支援再生医療研究会
- Place of Presentation
  長崎大学
- Year and Date
  2011-08-02
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by manipulation of signaling pathways2011
- Author(s)
  木村透
- Organizer
  The 9^<th> Stem Cell Research Symposium
- Place of Presentation
  泉ガーデンギャラリー(東京都)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] リン酸化シグナルによる生殖細胞と多能性幹細胞の相互転換2011
- Author(s)
  木村透
- Organizer
  第12回長崎障害者支援再生医療研究会
- Place of Presentation
  長崎大学(長崎県)(招待講演)
- Year and Date
  2011-08-02
- Data Source
  KAKENHI-PUBLICLY-23125508
[Presentation] 多能性幹細胞と始原生殖細胞の相互転換機構2011
- Author(s)
  木村透、李坤鵬、山野範子、仲野徹
- Organizer
  第10回日本再生医療学会シンポジウム「iPS・ES細胞の万能性と維持機構の解明～PluriPCtencyの正体とは～」
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] Metastable primordial germ cell-like stata induced from mouse embryonic stem cells by Akt activation2010
- Author(s)
  Kimura. T, Yamano.N, Shinohara T, and Nakano T
- Organizer
  The 8^<th> Stem Cell Researeh Sympogium
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.2010
- Author(s)
  Kimura T.
- Organizer
  第8回幹細胞シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] piRNA生合成におけるMVHの役割2010
- Author(s)
  宮川-倉持さとみ、渡部聡朗、高松加奈、中馬新一郎、後藤健吾、小島-北加奈子、城本悠助、伊藤大介、木村透、野瀬俊明、佐々木裕之、仲野徹
- Organizer
  第12回日本RBA学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20610002
[Presentation] Induction of the primordial germ cell-like states from mouse embryonic stem cells by manipulation of signaling pathways.2010
- Author(s)
  Kimura T, Yamano N, Li K-P, Sai tou M, Shinohara T, and Nakano T
- Organizer
  特定領域研究「生殖系列の世代サイクルとエピゲノムネットワーク」による国際シンポジウムInternational symposium on" Epigenome Network, Developmenta. and Reprogramming of Germ Cells"
- Place of Presentation
  九州大学
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] Induction of the primordial germ cell-like states from mouse embryonic stem cells by manipulation of signaling pathways.2010
- Author(s)
  Kimura T.
- Organizer
  International symposium on "Epigenome Network, Development and Reprogramming of Germ Cells"
- Place of Presentation
  九州大学医学部100年講堂
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] small RNAs and gene silencing in spermatogenesis2009
- Author(s)
  宮川(倉持)さとみ、後藤健吾、小島加奈子、高松可奈、勝俣明子、城本悠助、浅田徳子、木村透、野瀬俊明、仲野徹
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20610002
[Presentation] An Akt-signal dependent metastable pluripotency state showing primordial germ cell-like gene expression2009
- Author(s)
  Kimura. T, Yamano N, and Nakano T
- Organizer
  Cold Spring Harbor Symposium Stem Cell Biology Meeting
- Place of Presentation
  Cold Spring Harbor Laboratory, USA
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] PI3K/ Aktシグナルによる生殖細胞分化と幹細胞システムの制御2009
- Author(s)
  木村透
- Organizer
  国立成育医療センター研究所セミナー
- Place of Presentation
  国立成育医療センター研究所
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] An Akt-signal dependent metastable pluripotency stare showing primordial germ cell-like gene expression.2009
- Author(s)
  木村透
- Organizer
  Cold Spring Harbor Symposium
- Place of Presentation
  Cold Spring Harbor Lab (NY, USA)
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] マウス始原生殖細胞とその幹細胞性の制御2009
- Author(s)
  木村透
- Organizer
  日本受精着床学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] マウス始原生殖細胞とその幹細胞性の制御2009
- Author(s)
  木村透、山野範子、仲野徹
- Organizer
  第27回日本受精着床学会総会・学術講演会シンポジウム「生殖医療におけるstem cell biologyとその可能性」
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21390119
[Presentation] 分化多能性の獲得と維持におけるPI3K/Aktシグナルの機能2008
- Author(s)
  木村透、中村肇伸、山野範子、鈴木聡、仲野徹
- Organizer
  第6回幹細胞シンポジウム
- Place of Presentation
  学術総合センター
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] PI3K/Aktシグナルによる多能性幹細胞システムの制御2008
- Author(s)
  木村透、中村肇伸、山野範子、山本敏之、鈴木聡、仲野徹
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会合同学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] Regulation of Pluripotency in Mouse Primordial Germ Cells2008
- Author(s)
  Kimura T, Yamano N, Yamamoto T, and Nakano T.
- Organizer
  Cold Spring Harbor Symposium Germ Cell Meeting
- Place of Presentation
  Cold Spring Harbor Laboratory
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] PI3K/Aktシグナルによる多能性幹細胞システムの制御2008
- Author(s)
  木村透
- Organizer
  第31回曰本分子生物学会年会第81回日本生化学会合同学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] PI3K-Aktシグナルによる幹細胞システム制御2007
- Author(s)
  木村透、鈴木聡、仲野徹
- Organizer
  第40回日本発生生物学会、第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] Aktシグナルによる表皮幹細胞の活性化と前駆細胞の増幅2007
- Author(s)
  木村透、村山一茂、樽谷勝仁、林竜平、岡部勝、板見智、片山一朗、仲野徹
- Organizer
  第5回幹細胞シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] PI3K-Aktシグナルによる幹細胞システム制御2007
- Author(s)
  木村透
- Organizer
  第40回日本発生生物学会、第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19390113
[Presentation] Promotion of iPS cell induction by Akt signaling activation.
- Author(s)
  Fujikawa K & Kimura T
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  九州大学
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24390097
[Presentation] 始原生殖細胞の分化と脱分化
- Author(s)
  木村　透
- Organizer
  京都大学霊長類研究所研究会　「霊長類への展開に向けた幹細胞・生殖細胞・エピゲノム研究」
- Place of Presentation
  京都大学
- Year and Date
  2014-08-26 – 2014-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-24390097
[Presentation] Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds.
- Author(s)
  Kimura T et al.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  九州大学
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24390097
[Presentation] Induction of primordial germ cell-like cells from mouse embryonic stem cells by ERK signal inhibition.
- Author(s)
  Odamoto M & Kimura T et al.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  九州大学
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24390097

1. NAKANO Toru (00172370)

# of Collaborated Projects: 9 results

# of Collaborated Products: 15 results
2. NADA Shigeyuki (50291448)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TARUTANI Masahito (30301261)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. IKAWA Masahito (20304066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. Sekita Yoichi (20431950)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
6. 鈴木聡 (10311565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KITAJIMA Kenji (10346132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. MIYAGAWA Satomi (90291153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MURATA junko (80332740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. SHINOHARA Takashi (30322770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NOGUCHI Motoko (40021951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TOKUMOTO Toshinobu (30273163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NOZAKI Masami (30189394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 岡部勝 (30089875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 松本俊英 (10623184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OSAWA Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MATSUMOTO Kayoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大沢匡毅

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ISOTANI Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. ITAKURA Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. SATO Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. NAKAMURA Toshinobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 西山晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 倉持敏美

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
25. 岡田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 太田安隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Toru 木村 透

KIMURA Tohru 木村 透

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雌雄の生殖細胞の性分化を推進させるクロマチンリモデリング複合体の解析Principal Investigator

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Reciprocal conversion between germ cells and pluripotent stem cellsPrincipal Investigator

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マウスＰＩＷＩファミリーによる減数分裂期の染色体構造の制御Principal Investigator

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Analysis of phosphoryl at ionsignals in regulation of stem cell systemPrincipal Investigator

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Roles of phosphorylation signals in regulation of stem cell systemsPrincipal Investigator

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Mechanisms regulating mouse germline establishment and stem cell systemsPrincipal Investigator

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Analysis of mouse primordial germ cell development and stem cell systemsPrincipal Investigator

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Kimura Toru 木村透

KIMURA Tohru 木村透